LOCUS       DAVLIK010000001        82111 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLIK010000001 DAVLIK010000000
VERSION     DAVLIK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 82111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82111
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.001"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..158
                     /locus_tag="VXE87_000001"
     CDS             <1..158
                     /locus_tag="VXE87_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV0841629.1"
                     /translation="PNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYT
                     RGIWIRD"
     gene            554..1417
                     /locus_tag="VXE87_000002"
     CDS             554..1417
                     /locus_tag="VXE87_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0841630.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            1703..1903
                     /locus_tag="VXE87_000003"
     CDS             1703..1903
                     /locus_tag="VXE87_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0841631.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            1970..2635
                     /locus_tag="VXE87_000004"
     CDS             1970..2635
                     /locus_tag="VXE87_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0841632.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            2707..3933
                     /locus_tag="VXE87_000005"
     CDS             2707..3933
                     /locus_tag="VXE87_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0841633.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            4386..5042
                     /locus_tag="VXE87_000006"
     CDS             4386..5042
                     /locus_tag="VXE87_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0841634.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            5032..5355
                     /locus_tag="VXE87_000007"
     CDS             5032..5355
                     /locus_tag="VXE87_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0841635.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMILFILVKHKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            5460..6290
                     /locus_tag="VXE87_000008"
     CDS             5460..6290
                     /locus_tag="VXE87_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0841636.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            6444..7298
                     /locus_tag="VXE87_000009"
     CDS             6444..7298
                     /locus_tag="VXE87_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0841637.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            7398..8771
                     /locus_tag="VXE87_000010"
     CDS             7398..8771
                     /locus_tag="VXE87_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0841638.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            8764..9825
                     /locus_tag="VXE87_000011"
     CDS             8764..9825
                     /locus_tag="VXE87_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0841639.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            9827..10519
                     /locus_tag="VXE87_000012"
     CDS             9827..10519
                     /locus_tag="VXE87_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0841640.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(10549..11118)
                     /locus_tag="VXE87_000013"
     CDS             complement(10549..11118)
                     /locus_tag="VXE87_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0841641.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            11253..11867
                     /locus_tag="VXE87_000014"
     CDS             11253..11867
                     /locus_tag="VXE87_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0841642.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLVGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            11869..13515
                     /locus_tag="VXE87_000015"
     CDS             11869..13515
                     /locus_tag="VXE87_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0841643.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEF
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            13527..14813
                     /locus_tag="VXE87_000016"
     CDS             13527..14813
                     /locus_tag="VXE87_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0841644.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            14865..15398
                     /locus_tag="VXE87_000017"
     CDS             14865..15398
                     /locus_tag="VXE87_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0841645.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            15476..15946
                     /gene="nrdI"
                     /locus_tag="VXE87_000018"
     CDS             15476..15946
                     /gene="nrdI"
                     /locus_tag="VXE87_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0841646.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(16239..17501)
                     /locus_tag="VXE87_000019"
     CDS             complement(16239..17501)
                     /locus_tag="VXE87_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0841647.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDAVFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(17811..18269)
                     /locus_tag="VXE87_000020"
     CDS             complement(17811..18269)
                     /locus_tag="VXE87_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0841648.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(18266..18706)
                     /locus_tag="VXE87_000021"
     CDS             complement(18266..18706)
                     /locus_tag="VXE87_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0841649.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19062..21011
                     /gene="mutL"
                     /locus_tag="VXE87_000022"
     CDS             19062..21011
                     /gene="mutL"
                     /locus_tag="VXE87_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0841650.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(21336..21803)
                     /locus_tag="VXE87_000023"
     CDS             complement(21336..21803)
                     /locus_tag="VXE87_000023"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0841651.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(21804..23009)
                     /locus_tag="VXE87_000024"
     CDS             complement(21804..23009)
                     /locus_tag="VXE87_000024"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0841652.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(23029..23664)
                     /gene="ribE"
                     /locus_tag="VXE87_000025"
     CDS             complement(23029..23664)
                     /gene="ribE"
                     /locus_tag="VXE87_000025"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0841653.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(23649..24749)
                     /gene="ribD"
                     /locus_tag="VXE87_000026"
     CDS             complement(23649..24749)
                     /gene="ribD"
                     /locus_tag="VXE87_000026"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0841654.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVQQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(24883..24997)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25154..25747
                     /gene="ruvA"
                     /locus_tag="VXE87_000027"
     CDS             25154..25747
                     /gene="ruvA"
                     /locus_tag="VXE87_000027"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0841655.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            25757..26320
                     /locus_tag="VXE87_000028"
     CDS             25757..26320
                     /locus_tag="VXE87_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0841656.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQA
                     GLSWETVLNKRQAFREVFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            26317..26994
                     /locus_tag="VXE87_000029"
     CDS             26317..26994
                     /locus_tag="VXE87_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0841657.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(27149..28180)
                     /locus_tag="VXE87_000030"
     CDS             complement(27149..28180)
                     /locus_tag="VXE87_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0841658.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCPKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(28435..29118)
                     /locus_tag="VXE87_000031"
     CDS             complement(28435..29118)
                     /locus_tag="VXE87_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0841659.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(29130..30074)
                     /locus_tag="VXE87_000032"
     CDS             complement(29130..30074)
                     /locus_tag="VXE87_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0841660.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            30206..33037
                     /gene="uvrA"
                     /locus_tag="VXE87_000033"
     CDS             30206..33037
                     /gene="uvrA"
                     /locus_tag="VXE87_000033"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0841661.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKADVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            33030..34091
                     /locus_tag="VXE87_000034"
     CDS             33030..34091
                     /locus_tag="VXE87_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0841662.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            34223..34621
                     /gene="spx"
                     /locus_tag="VXE87_000035"
     CDS             34223..34621
                     /gene="spx"
                     /locus_tag="VXE87_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0841663.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            34687..35256
                     /locus_tag="VXE87_000036"
     CDS             34687..35256
                     /locus_tag="VXE87_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0841664.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKIYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            35343..35609
                     /locus_tag="VXE87_000037"
     CDS             35343..35609
                     /locus_tag="VXE87_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0841665.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            35613..36032
                     /gene="ruvX"
                     /locus_tag="VXE87_000038"
     CDS             35613..36032
                     /gene="ruvX"
                     /locus_tag="VXE87_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0841666.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            36048..36353
                     /locus_tag="VXE87_000039"
     CDS             36048..36353
                     /locus_tag="VXE87_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0841667.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            36608..37858
                     /locus_tag="VXE87_000040"
     CDS             36608..37858
                     /locus_tag="VXE87_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0841668.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTEELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            37855..38400
                     /locus_tag="VXE87_000041"
     CDS             37855..38400
                     /locus_tag="VXE87_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0841669.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            38546..40078
                     /gene="cls"
                     /locus_tag="VXE87_000042"
     CDS             38546..40078
                     /gene="cls"
                     /locus_tag="VXE87_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0841670.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            40336..41874
                     /locus_tag="VXE87_000043"
     CDS             40336..41874
                     /locus_tag="VXE87_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0841671.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            41994..44201
                     /gene="nrdD"
                     /locus_tag="VXE87_000044"
     CDS             41994..44201
                     /gene="nrdD"
                     /locus_tag="VXE87_000044"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0841672.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            44213..44353
                     /locus_tag="VXE87_000045"
     CDS             44213..44353
                     /locus_tag="VXE87_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841673.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKYSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            44397..44903
                     /locus_tag="VXE87_000046"
     CDS             44397..44903
                     /locus_tag="VXE87_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0841674.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            44896..45486
                     /gene="nrdG"
                     /locus_tag="VXE87_000047"
     CDS             44896..45486
                     /gene="nrdG"
                     /locus_tag="VXE87_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0841675.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            45483..46100
                     /locus_tag="VXE87_000048"
     CDS             45483..46100
                     /locus_tag="VXE87_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0841676.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTLAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRFARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            46355..46663
                     /gene="rpsJ"
                     /locus_tag="VXE87_000049"
     CDS             46355..46663
                     /gene="rpsJ"
                     /locus_tag="VXE87_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0841677.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            46879..47505
                     /gene="rplC"
                     /locus_tag="VXE87_000050"
     CDS             46879..47505
                     /gene="rplC"
                     /locus_tag="VXE87_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0841678.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            47530..48153
                     /gene="rplD"
                     /locus_tag="VXE87_000051"
     CDS             47530..48153
                     /gene="rplD"
                     /locus_tag="VXE87_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0841679.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            48153..48449
                     /locus_tag="VXE87_000052"
     CDS             48153..48449
                     /locus_tag="VXE87_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0841680.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            48467..49300
                     /gene="rplB"
                     /locus_tag="VXE87_000053"
     CDS             48467..49300
                     /gene="rplB"
                     /locus_tag="VXE87_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0841681.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            49404..49685
                     /gene="rpsS"
                     /locus_tag="VXE87_000054"
     CDS             49404..49685
                     /gene="rpsS"
                     /locus_tag="VXE87_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0841682.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            49697..50041
                     /gene="rplV"
                     /locus_tag="VXE87_000055"
     CDS             49697..50041
                     /gene="rplV"
                     /locus_tag="VXE87_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0841683.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            50054..50707
                     /gene="rpsC"
                     /locus_tag="VXE87_000056"
     CDS             50054..50707
                     /gene="rpsC"
                     /locus_tag="VXE87_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0841684.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            50711..51124
                     /gene="rplP"
                     /locus_tag="VXE87_000057"
     CDS             50711..51124
                     /gene="rplP"
                     /locus_tag="VXE87_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0841685.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            51134..51340
                     /locus_tag="VXE87_000058"
     CDS             51134..51340
                     /locus_tag="VXE87_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0841686.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            51365..51625
                     /gene="rpsQ"
                     /locus_tag="VXE87_000059"
     CDS             51365..51625
                     /gene="rpsQ"
                     /locus_tag="VXE87_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0841687.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            51651..52019
                     /gene="rplN"
                     /locus_tag="VXE87_000060"
     CDS             51651..52019
                     /gene="rplN"
                     /locus_tag="VXE87_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0841688.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            52097..52402
                     /gene="rplX"
                     /locus_tag="VXE87_000061"
     CDS             52097..52402
                     /gene="rplX"
                     /locus_tag="VXE87_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0841689.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            52426..52968
                     /gene="rplE"
                     /locus_tag="VXE87_000062"
     CDS             52426..52968
                     /gene="rplE"
                     /locus_tag="VXE87_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0841690.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            52986..53255
                     /gene="rpsN"
                     /locus_tag="VXE87_000063"
     CDS             52986..53255
                     /gene="rpsN"
                     /locus_tag="VXE87_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0841691.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            53540..53938
                     /gene="rpsH"
                     /locus_tag="VXE87_000064"
     CDS             53540..53938
                     /gene="rpsH"
                     /locus_tag="VXE87_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0841692.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGSNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            54130..54666
                     /gene="rplF"
                     /locus_tag="VXE87_000065"
     CDS             54130..54666
                     /gene="rplF"
                     /locus_tag="VXE87_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0841693.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            54750..55106
                     /gene="rplR"
                     /locus_tag="VXE87_000066"
     CDS             54750..55106
                     /gene="rplR"
                     /locus_tag="VXE87_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0841694.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            55124..55618
                     /gene="rpsE"
                     /locus_tag="VXE87_000067"
     CDS             55124..55618
                     /gene="rpsE"
                     /locus_tag="VXE87_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0841695.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            55590..55814
                     /gene="rpmD"
                     /locus_tag="VXE87_000068"
     CDS             55590..55814
                     /gene="rpmD"
                     /locus_tag="VXE87_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0841696.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            55959..56399
                     /gene="rplO"
                     /locus_tag="VXE87_000069"
     CDS             55959..56399
                     /gene="rplO"
                     /locus_tag="VXE87_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0841697.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            56412..57722
                     /gene="secY"
                     /locus_tag="VXE87_000070"
     CDS             56412..57722
                     /gene="secY"
                     /locus_tag="VXE87_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0841698.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            57873..58511
                     /locus_tag="VXE87_000071"
     CDS             57873..58511
                     /locus_tag="VXE87_000071"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0841699.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            58628..58846
                     /gene="infA"
                     /locus_tag="VXE87_000072"
     CDS             58628..58846
                     /gene="infA"
                     /locus_tag="VXE87_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0841700.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            58871..58987
                     /gene="rpmJ"
                     /locus_tag="VXE87_000073"
     CDS             58871..58987
                     /gene="rpmJ"
                     /locus_tag="VXE87_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0841701.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            59005..59370
                     /gene="rpsM"
                     /locus_tag="VXE87_000074"
     CDS             59005..59370
                     /gene="rpsM"
                     /locus_tag="VXE87_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0841702.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            59388..59771
                     /gene="rpsK"
                     /locus_tag="VXE87_000075"
     CDS             59388..59771
                     /gene="rpsK"
                     /locus_tag="VXE87_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0841703.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            59814..60749
                     /locus_tag="VXE87_000076"
     CDS             59814..60749
                     /locus_tag="VXE87_000076"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0841704.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGIDTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            60761..61147
                     /gene="rplQ"
                     /locus_tag="VXE87_000077"
     CDS             60761..61147
                     /gene="rplQ"
                     /locus_tag="VXE87_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0841705.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            61412..61678
                     /locus_tag="VXE87_000078"
     CDS             61412..61678
                     /locus_tag="VXE87_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0841706.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            61688..63025
                     /locus_tag="VXE87_000079"
     CDS             61688..63025
                     /locus_tag="VXE87_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0841707.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            63269..63961
                     /locus_tag="VXE87_000080"
     CDS             63269..63961
                     /locus_tag="VXE87_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0841708.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(64064..65716)
                     /locus_tag="VXE87_000081"
                     /pseudo
     CDS             complement(64064..65716)
                     /locus_tag="VXE87_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(65706..66011)
                     /locus_tag="VXE87_000082"
                     /pseudo
     CDS             complement(65706..66011)
                     /locus_tag="VXE87_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            complement(66138..66797)
                     /locus_tag="VXE87_000083"
     CDS             complement(66138..66797)
                     /locus_tag="VXE87_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841709.1"
                     /translation="MSEIKIINAKKIYHDVPVIENLNITIPKGSLFTLLGPSGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMNEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            complement(66810..67931)
                     /locus_tag="VXE87_000084"
                     /pseudo
     CDS             complement(66810..67931)
                     /locus_tag="VXE87_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(68148..68345)
                     /locus_tag="VXE87_000085"
     CDS             complement(68148..68345)
                     /locus_tag="VXE87_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0841710.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(68420..69196)
                     /locus_tag="VXE87_000086"
     CDS             complement(68420..69196)
                     /locus_tag="VXE87_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0841711.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            69318..70064
                     /locus_tag="VXE87_000087"
     CDS             69318..70064
                     /locus_tag="VXE87_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0841712.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            70077..71057
                     /locus_tag="VXE87_000088"
     CDS             70077..71057
                     /locus_tag="VXE87_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0841713.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            71252..71572
                     /locus_tag="VXE87_000089"
     CDS             71252..71572
                     /locus_tag="VXE87_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0841714.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            71618..71926
                     /locus_tag="VXE87_000090"
     CDS             71618..71926
                     /locus_tag="VXE87_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0841715.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            71943..73241
                     /locus_tag="VXE87_000091"
     CDS             71943..73241
                     /locus_tag="VXE87_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0841716.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            73392..75830
                     /locus_tag="VXE87_000092"
     CDS             73392..75830
                     /locus_tag="VXE87_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0841717.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            75849..76517
                     /locus_tag="VXE87_000093"
     CDS             75849..76517
                     /locus_tag="VXE87_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0841718.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            76535..77623
                     /locus_tag="VXE87_000094"
     CDS             76535..77623
                     /locus_tag="VXE87_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0841719.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            78078..80579
                     /locus_tag="VXE87_000095"
     CDS             78078..80579
                     /locus_tag="VXE87_000095"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0841720.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTS
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIVAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFVQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVIAVPNKLVNIVVK"
     gene            80774..81469
                     /locus_tag="VXE87_000096"
     CDS             80774..81469
                     /locus_tag="VXE87_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0841721.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQESVADMEELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPKLRGTRIGTEAQYLLARYVFEELNYRRYEWKCDSL
                     NLPSRRAAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKARLEAWLTPENF
                     DKTGQQYKSLREL"
     gene            81481..81897
                     /locus_tag="VXE87_000097"
     CDS             81481..81897
                     /locus_tag="VXE87_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0841722.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YVALDGDAVVGLIRLVGDGFSSVFVQDLIVLPNYQRQGIGSLLMKEALKDYKDAYQVQ
                     LVTEETEKNVRFYRSMGFEALSTYDCIGMTWVNREK"
BASE COUNT        24819 a        14942 c        17881 g        24469 t
ORIGIN      
        1 aaccaaattt aaacgttagt atagataacg taatttttga aaagaatttt gaactattta
       61 caaaacaaag tgatctaatt gttgcaaata gatgggatag gggccttgaa gcttataaag
      121 ataaagttta cacaaggggg atctggataa gagattaact attgatatta aaaaggcaat
      181 aatttataaa atttgtacaa aaaaatgtta aattttcaca ttttcatagt atactgttta
      241 atagaaagta ggttctttgt aaccgctcca ttataaaatc ctttcactct tccggtatac
      301 tattaggaaa aacataactg gaggatattt tgagctcaca cctcatcgtt ccagtggctg
      361 ttccccaagc tcgtgtactg cccaaaaaag ttagacattc tatttagaac gaggattgag
      421 ttctgtattg tacaaggctc ggtcctttta gagtcagctt aaggctggct tttttatttt
      481 ttctaactat cagaatattt tgacaaatga acacaaataa tgatataata tgcaaaagct
      541 aggaggtggt aggatgattg aaaaaatgga attgggggaa ttttacaagg aattacgttt
      601 ggcgagaaag ctcaagcagt cagatgtggc ttgtgacggg ctaacagctt ctcagttgtc
      661 caagtttgag ctagggcagt ccatgttgtc tgctgataag ctcatattag ccatccaagg
      721 gatcaatgtg acctttgatg agtttgggca caagctcaac aactatcaag aatctccaca
      781 tatgcagatt ggtagaaagg ttgtggatcg ctttgctcat caagatatag ctggcttaga
      841 gcaactgttg gaggaagtcg agcaagaaca gatggcagag acttatcgtc gtttgaatgc
      901 tattgtaatc aaagatgcca tccactcact agataaaagc tacccactag cagaggagga
      961 tagcgagttt ttgaccacct atctctatgc tatcgagtct tggacctggt ttgaactcta
     1021 tctcttttgc aatactctgc ccttcttgag caatcaagat ctgatctttt tatcaacctc
     1081 cttactcgaa aaatccaaag aatttaaaga gttagtacac aatcgattgt atatgaagca
     1141 aggactctta aatatcatct cagagctcat ggagcgcaaa cttttttctt atatcccaat
     1201 ctttgaagcc gagctggaga gtatgctccg tccatacgat gtttttgaga aagtgttgtg
     1261 gcagttttta aagaagatga gcattttcct tcaaactaag ggaagcaatc aaaaagagat
     1321 tgaacacttt atccaatctc tgcaagtatt agaaaatcca caattaatag ccctttttga
     1381 attgcgtttg cagcaataca aaaagcttat cgattagtta gaaatggcaa aataataata
     1441 atctcagcaa cgattttcaa taatgttaaa atttgtttct tcatatttct ccactcctca
     1501 ttagtagtaa ctttattata ccagagaagt aatcaaattc accaaaatcg caaatctgaa
     1561 atttctataa gaaaaaatat caaatatgcg attttctaaa ataagccaat tttcgtgtta
     1621 tactgtactt gtaaagcact tgaagcaaat cctaggtcac agaagtggtt tacaaatgaa
     1681 gataattgaa ggagtgtaaa agatgttaaa tttacaattt gcagaaacaa tggaattgac
     1741 agaagctgag ttggagatag tttatggagg ggaatttggg aataatgctg ttatcccagc
     1801 cggtgcttgg ggagggttcg ggacaccttg gtcaatcact aatttctgga agaaaaattt
     1861 taacgataga cctgactttg attctgaccg ccgtcgttat taatatccaa agcccttgcc
     1921 ttttcttggg taggggctgt ctttatttca tagtatagga ggaaatagaa tgaaaaagat
     1981 aatctcacac cgctacttta ttatagtttt tctactagtt attgctgacc agaagttcag
     2041 tgttctagtt ttacgcagcg accttgttac tgggctatct gactttgcct attatctgtc
     2101 ggatatgatg ttgaattttc ttgtggtttt atttgctctt attgctatga tttggtcggg
     2161 gaaatggcag aaaatcaata gtagaaagtt taaaggatcc tatcttttct attccttcct
     2221 agctctgctt gcttttgttg tttggaattt cgttaccttt tttcttttcc cacctactcg
     2281 aaatgaaatt tcttatcaac atgctgctcc gacttttaca ggggctacag catttttgat
     2341 gtattttttc tatcctgtga ttgcaggtcc catttttgaa gagataatcc atcggggatt
     2401 ggtgatgaca gctctggaaa aaggaaagaa atgggggcta gatgtacttg gctctgctat
     2461 tttatttggg gtctcgcaca ttagtaatca cggttgggtc ttgacagact ttgtcttcta
     2521 tatgggtgga ggtcttatat ttgcagtctt atttagaatg acaaagtcaa tttattggcc
     2581 tattggactg catatagtct acaatggtat tggtcagctt ttgatgttac tgtaattttg
     2641 gttgttagta gtatcgcggt ctattcttgg ggaaagattc ccatttgaac ttaagaagga
     2701 gttgtaatga aagtatttct tcaaaataga gattttaggc aattaactat caaccagtgg
     2761 atttcaacgc ttggggatac gattttttat ctggccttcc tgaattatgt ggcagatgcg
     2821 tcttttgccc ctttggcgat tttacttatc acgatttcag aaacccttcc ccaagttcta
     2881 caaatctttc tgggagtttt ggcggatttt caacatcatc gtgtcttgaa atacacagtc
     2941 attagtttta caaaattttt gctttactct atagtgtccc tatcgctttc agggcagtct
     3001 ttttccttgt tgctagtaac ctttatttgt atgattaacc tcttgtctga cacattgagt
     3061 tatttttcag gcgccatgct cactccgatt ttcattagaa ttattgggca agatcatctg
     3121 gcagaagcta ttggatttaa acagtcaact gttagtttag tgaaaacaat cagtaatatc
     3181 ctaggaggag tcttactagg tattctatcc atccagttta tttccttact gaacgctctt
     3241 acctttttaa tcgcattttt aggtatcctc ttcataaaaa ctgacctctt gaaagtagaa
     3301 aaaacgatta gctatcaaga aggactctct gtaaaatcct tttgccagca tttgctccaa
     3361 tcatcgaaat tgatatggaa tatgaataag gtgctcttgg ttttgtttat tatctctact
     3421 agtcaagcag tgataaatgt tacagttcct gtctctactc tatttttgag gaatcaaccc
     3481 tttttgaatt tacaaacagg tcaatctctt gccttgctat ccacttttga actgtcagcc
     3541 ctgattgtcg gaagccttgt aagtggctat ctgcaacata ccatttccat aaaaacagct
     3601 ctctatgcct cacttgtcat ccagttgctt cttctagtag gatttgccac agttcgtttt
     3661 gactggattc tcatctttag taccttggat gcctttttcg caggtgttct ctctcctaga
     3721 ttgcaagaac tcgtctttaa acaaatacct gaggagtcaa tgggagcagt tcaatcttct
     3781 atcagtgcca ttacggttgt tttacctagc ttatttacaa tatctttggt aaccattgct
     3841 actagctttg gaactctggc agttagcttt gttttattgc tatttcttct agttgccttt
     3901 gttatgcttc tgaatattcg tgaaagtatt tagtggagaa tttctataat atatgtttga
     3961 gactggattg ccagtctttt tatgatggtc aaaatcaaca gactttttct cttttctgaa
     4021 tgtgttatag tagactgaat ctaaaatagt acgaaacaat tgctaaaaca tttatagaaa
     4081 ttaattttac tttcccaatc gatttgttct catcttattt caatctgcta tataatagtc
     4141 catgctgtgg ctggattctt ttcagcctac ttatactctt cgaaactctc ttcaaaccac
     4201 gtcagcttca ccttgccgta tatgtgttac tgacttcgtc agttctatcc acaacctcaa
     4261 aacggtgttt tgagcaacct gcggctagtt tcctagtttg ctctttgatt ttcattgagt
     4321 attattaaaa caatatgagg agaaagatga aagaaaaagg attttaggag ggggcgcagg
     4381 cagccatgcc aacggctctt ggctatgtca gtatcggcct ggcctgtggg actatcggtg
     4441 ctccctatgt gacacctgtt gagatgggct tgatgagtct ctttgtttat gctgggagtg
     4501 cccagtttgc catgttggca ctgattgtgg ttcaagctcc tgtggcagct attgctatga
     4561 cggtttttct aatcaacttg cgtctctttt tgttgagttt acacgcatcg acttatttcc
     4621 gtcataccag tctttggtac aatatcggta tgtctagtat cttgacagat gagacctatg
     4681 gcgttttgat gggtgaattg gcccatacag acaaggtaaa tcctatgtgg atgcacggga
     4741 acaatctcaa cagctatgtg gcttggtttg tggggacagt agtcggaacg gctctgggtg
     4801 gcctgctacc aaatccagaa atctttggct tggattttgc cctggttggg atgtttattg
     4861 gtatttttgc ttcgcaattt cagattatgc aaagacggat tcctgtccgc aatctgctca
     4921 ttatcctagc agttgttgcg gtgtccttct ttttgctctt gacagtggtg tctcagtcac
     4981 tagctgttct gtttgcgacg ctacttggtt gtagcatggg ggtggtttta gatggtcagt
     5041 aagtatcttt tattagcagt tattttctct ggtcttgtga cctggattcc ccgtatgatt
     5101 ctcttcatct tggtcaagca taagggcctg cctgcgattg ttgagcgttt tttgaagttt
     5161 ttgcctgttt ccattatctt tgccttgatt ctttcaagcg tagtgacagg taaggttggg
     5221 agccttcctc aaattaaatg gctagacttc ttagccgtct ttccaacagc ttgggtagcc
     5281 tttcgctacc gcaatctagt cggaacagtt ctctttggag tggtcttgat tgccatcttg
     5341 cgtttggtct tttaaattac ccataaaaaa aaacttatca cagagataga tatcatataa
     5401 tggcgtaaat gctctttttc tgttaagatt ataaggtatt ctattttgga ggaaatgaca
     5461 tgaaaaaaat cgttaaatac tcatctcttg cagcccttgc tcttgttgct gcaggtgtgc
     5521 ttgcggcttg ctcaggtggt gctaagaaag aaggacaagc agctagcaag aaagaaatca
     5581 tcgttgcaac caatggatca ccaaggccat ttatctatga agaaaatggc gaattgactg
     5641 gttacgagat tgaagtcgtt cgcgctatct ttaaagattc tgacaaatat gatgtcaagt
     5701 ttgaaaagac agaatggtca ggtgtctttg ctggtcttga cgctgaccgt tacaatatgg
     5761 ctgtcaacaa tcttagctac actaaagaac gtgcggagaa atacctctat gccgcaccaa
     5821 ttgcccaaaa tcctaatgtc cttgtcgtga agaaagatga ctctagtatc aagtctctcg
     5881 atgatatcgg tggaaaatcg acggaagtcg ttcaagccac tacatcagct aagcagttag
     5941 aagcatacaa cgctgaacac acggacaacc caactatcct taactatact aaggcagatt
     6001 tccaacaaat catggtacgt ttgagcgatg gacaatttga ctataagatt tttgataaaa
     6061 tcggtgttga aacagtgatc aagaaccaag gtttggacaa cttgaaagtt atcgaacttc
     6121 caagcgacca acaaccgtac gtttacccac ttcttgctca gggtcaagat gagttgaaat
     6181 cgtttgtaga caaacgcatc aaagaacttt ataaagatgg aactcttgaa aaattgtcta
     6241 aacaattctt cggagacact tatctaccgg cagaagctga tattaaataa tttcttgaaa
     6301 tcatccattc tgagtaagat gggtggtttc tcagttttta gggatatagt tttaaactat
     6361 atatctgact atctaataac aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt
     6421 attattttta aggagaaaga atcatgaaaa tcaaaaaatg gcttggtcta gcagcccttg
     6481 ctacagtcgc aggtttggct cttgcagctt gcggaaactc agaaaagaaa gcagacaatg
     6541 caacaactat caaaatcgca actgttaacc gtagcggttc tgaagaaaaa cgttgggaca
     6601 aaatccaaga attggttaaa aaagacggaa ttaccttgga atttacagag ttcacagact
     6661 actcacaacc aaacaaagca actgctgatg gcgaagtaga tttgaacgct ttccaacact
     6721 ataacttctt gaacaactgg aacaaagaaa acggaaaaga ccttgtagcg attgcagata
     6781 cttacatctc tccaatccgc ctttactcag gtttgaatgg aagtgccaac aagtacacta
     6841 aagtagaaga catcccagca aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa
     6901 gccgtgcgct ttacttgctt caatcagctg gcttgattaa attggatgtt tctggaactg
     6961 ctcttgcaac agttgccaac atcaaagaaa atccaaagaa cttgaaaatc actgaattgg
     7021 acgctagcca aacagctcgt tcattgtcat cagttgacgc tgccgttgta aacaatacct
     7081 tcgttacaga agcaaaattg gactacaaga aagcactttt caaagaacaa gctgatgaaa
     7141 actcaaaaca atggtacaac atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg
     7201 ctgatgctat caagaaagta atcgcagctt accacacaga tgacgtgaaa aaagttatcg
     7261 aagaatcatc agacggtttg gatcaaccag tttggtaata agaaacaggg aggtgggaga
     7321 gagaattcca cctcttgctt ttgtatagag cacggagtgt aaagaagact attcgttcat
     7381 agaaaggtag agagaatatg gtttttccta gcgaacaaga acagattgaa aaatttgaaa
     7441 aggatcatgt agcccagcat tattttgagg ttttgcgtac cttgatttct aagaaatcag
     7501 tctttgccca gcaggttgga ctcaaggaag tcgcaaatta tctgggtgag attttcaagc
     7561 gtgttggagc tgaagtggag attgatgaga gctatacagc gccctttgtc atggcacatt
     7621 tcaagagttc gcgtccagat gccaagacct tgattttcta taaccactat gacactgtgc
     7681 cagcggatgg ggatcaggtc tggacagagg atccttttac gctttcggtc cgcaatggct
     7741 tcatgtatgg gcgtggagtt gatgacgaca agggtcatat cacagctcgc ttgagtgctt
     7801 tgagaaaata tatgcagcac catgatgatt tacctgtcaa tatcagcttt atcatggagg
     7861 gagcggagga atcggcttca acagacctag ataagtattt ggaaaagcat gcagacaaac
     7921 tccgtggggc ggatttgttg gtctgggaac aagggaccaa aaatgccttg gaacagctgg
     7981 aaatttctgg tggcaataag gggattgtga cctttgatgc caaggtaaaa agcgctgatg
     8041 tggatatcca ctcgagttat ggtggtgttg tggaatcagc tccttggtat ctcctccaag
     8101 ccttacagtc tcttcgtgct gcggatggcc gtatcttggt tgaaggcttg tacgaagaag
     8161 tacaagagcc caatgaacga gaaatggcct tgctagaaac ttatggtcaa cgaaacccag
     8221 aggaagttag tcggatttat ggattggagt tgcctctctt acaggaggag cggatggcct
     8281 ttctaaaacg tttctttttc gagccagcgc ttaatatcga aggaatccag tctggttatc
     8341 aaggtcaggg tgtgaagact attttacctg cagaagccag tgccaagcta gaggttcgtc
     8401 tggttccggg cctagaaccg catgatgttc tggaaaaaat tcggaaacag ctagacaaaa
     8461 atggctttga taaggtagaa ttatactata ccttgggaga gatgagctat cgaagcgata
     8521 tgagcgcacc agccattctc aatgtgatcg agttggccaa gaaattctat ccacagggcg
     8581 tttcagtctt gccgacgaca gcggggacag gacctatgca tacggtcttt gatgccctag
     8641 aggtaccaat ggttgcattc ggtctaggaa atgccaatag ccgagaccac ggtggagatg
     8701 aaaatgtgcg aatcgctgat tattacaccc atatcgaatt agtagaggag ctgattagaa
     8761 gctatgagta gagatattat caagttagat cagatcgatg tgacttttca ccaaaagaag
     8821 agaaccatca cagcggttaa ggatgtgacc attcacatcc aagaagggga tatctacgga
     8881 atcgttggat attctggagc agggaaatca acccttgtac gggtgattaa tctcttgcaa
     8941 aaaccatctg cagggaaaat taccattgac gacgatgtga tttttgatgg taaggtcacc
     9001 ttgacggcag agcagttgcg tcgtaaacgt caagatatcg ggatgatttt ccagcatttt
     9061 aacctgatga gtcaaaagac agcagaggag aatgtagcct ttgcccttaa acactctgga
     9121 ctcagcaagg aagaaaagaa ggctaaagta gctaagttgt tggacttggt tggtttggca
     9181 gatcgtgctg aaaactaccc ttcacaatta tctggagggc aaaaacagcg tgtggcaatt
     9241 gcgcgtgcct tggccaatga tccaaaaatc ttgatttcag acgagtcaac ttctgccctt
     9301 gaccctaaga caaccaagca gattttggcc ttgttgcaag atttgaacca aaaattaggc
     9361 ttgactgttg tcttgattac gcatgaaatg cagattgtca aagacattgc caaccgtgtt
     9421 gcagttatgc aggatgggca tttgattgaa gagggtagtg tgcttgaaat cttctcaaac
     9481 cctaaacaac ctttgactca agactttatc tcaacagcta caggtattga cgaagccatg
     9541 gtcaaaatcg agaagcaaga aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa
     9601 ctcaagtacg ctggagcttc aacagacgag ccacttttga atgaattgta caagcattac
     9661 caagtaatgg ctaatattct ctatgggaat atcgaaattc tcgatggtac tcctgttgga
     9721 gaattggtgg tggttttgtc aggtgaaaaa gcagcgttgg caggtgccca agaagccatt
     9781 cgtcaagcag gtgtacaact aaaagtattg aagggagtac agtaagatgg aatcattgat
     9841 tcaaacctat ttaccaaatg tctataaaat gggttgggct ggtcaggcag gctggggaac
     9901 ggctatctac ttaactcttt atatgacagt tctttccttc attatcggag gcttcttggg
     9961 gctagtggca ggtctctttc tcgtcttgac agcgccaggt ggtgtcttgg agaataaagt
    10021 cgtattctgg attttagaca aaattacctc aatttttcgt gcggttccct ttatcatcct
    10081 cttggcaatc ttgtcaccac tttctcactt gattgttaaa acaagtatcg ggccaaatgc
    10141 agcccttgtc ccactttctt ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt
    10201 cttggctgaa ttggatggcg gtgtcattga ggcggctcaa gcgagcggag cgactttctg
    10261 ggacatcgtg ggtgtttacc tatcagaagg tcttccagat ttgatccgtg tgacgactgt
    10321 gaccttgatt tcccttgttg gggaaacagc tatggccggt gcggttggag ctggtggtat
    10381 cggtaacgta gccatcgctt atggatttaa ccgctacaat cacgatgtga ccatcttggc
    10441 aaccatcatt atcattttga ttatctttgc aatccaattc ttgggagatt tcttgactaa
    10501 gaaattgagc cataaataaa aaagagccgc gtggctcttt ttaactgatc agattttctg
    10561 tgcaaatttt ttactcaagg cttgtccaat caaggcaccc actagggctc cgatgacaat
    10621 acttgcgata aatagaagga cagttccagg gtttggagcg accatgatgc ggtcgatata
    10681 ttcttgggat tttcctcttg ccagaagagt agccatatag gctttgggcg caatccacat
    10741 aagcaagatt ggtcctgttg tactaaaggc gaaaataatg aaagaaagga agttctttgt
    10801 tttgtccttg tattttccta aatgagctac ttcatctgct aggaggccac agataattcc
    10861 aggaaggaag gaaccagcac cgtgtttagt tcccaagaaa aagagggcaa tgacaaggcc
    10921 gatagtggta atggctccaa agcgcggaac ttttgcgact aggatcatat agacgctacc
    10981 gccgacaagg gcagtaaagg caggcgcata aaacatgttt ccagtttggt caaagagatt
    11041 gcccaaaagg acaccaatcc ccatgcagag gaagtaaaga actgcaaaaa gcagtgtagt
    11101 taagatagat ttcttcatga attgtctcct gataattttt tcacaattct cattgtacca
    11161 cggtttggtg ggattgtaaa tggatactag aagtttttga aaacgcttga aatatgatat
    11221 aatggtttca tagttatttt taggggaata tcatgggtag atttttagac tttgtcttta
    11281 atcgtttctt tttagggatg attgcgacag ccttcttttg gctattaact ttagtaggag
    11341 ggattatcct tggtctagcg ccagctagtg ccaccttgat gagcttatat gcagaacatg
    11401 gttatagctt tcgggaatac agtttgaagg aggcttggtc tctttacaag caaaattttg
    11461 tctcaagcaa cctgattttc tatagctttt taggtgtggg tctagttttg acctatggtt
    11521 tgtatctctt ggtgcaattg cctcatcaga ccattgttca tttgattgcg acccttttga
    11581 atgtcctagt agttgccctg atctttttgg cttatacagt atctttaaaa ttacaagttt
    11641 attttgcctt gtcctatcga aatagtctca aattatcctt gattggcatc tttatgagtc
    11701 tagcagctgt ggccaagatt ctccttggga ctgtgctact tgtagcaatt ggttactata
    11761 tgcctgccct gctatttttt gtaggaattg ggatgtggca tttctttatc agtgatatgt
    11821 tggaacctgt ctatgaaatc atccatgaaa aattggcgac aaaatagaat gaagcacttt
    11881 tggctacata cgcttctaag aacctatagt tcagtgatga tcattatcat tgcgagtttt
    11941 gcaatcttac tctcttacgc tgactgggat tcacgtgaaa aggaagccca gagagtagcc
    12001 cagcgtgtaa ctgctagaac agtgagtgaa attgaatatt accatagaga gtcaacccag
    12061 atagctcagg ctttagttga aaaccaagct cgtattgagg gaatctataa atactttagc
    12121 cttagcatgc cagactattt ttactggcaa ttagagcgga aagcttcgcc ttatatatca
    12181 gtctctctgt atgaaaatgt tgatgacctc tatgttcgaa atgattttgt aactggggtg
    12241 gccattgctt ttcaagatta caaggaagtc tatgtttcta ctaaagacaa acgtagtgga
    12301 gaaaaaatca gggctgagga tttcaaacca gcaggaaata gttttgccat tccggtgtca
    12361 gatccagtgt cagatcaaga tttaggagtg atttacatct ccttggatcc tgctgtttta
    12421 taccatgcca ttgataatac tagaggtcat actccgatgg cagtaacagt gacctcacct
    12481 tttgatacgg agatttttca tattggtgag acagttgata gggagagtga aaattggcta
    12541 gttggcttaa cttctcatgg atatcaggtt caggtggcag ttcctaaaaa ctttgtttta
    12601 caaggaacag tgactagctc tgctttgatt gtgggtttga gccttctctt tattgtcatt
    12661 ctttatctga ctttgaggca gacttttgct aattaccaaa agcaggtagt ggatttagta
    12721 gaatccattc aagtcattgc tcaaggcgaa gaggggcgtc ggattgacat ttccgagaaa
    12781 gatcaggaat tactcctaat cgcggagacg accaatgata tgttggatcg attggaaaag
    12841 aatatccatg atatttacca gttagagttt agtcaaaaag atgccaatat gcgagccttg
    12901 caggcgcaaa tcaatcctca ttttatgtat aatacgctgg agttcttgcg catgtatgca
    12961 gttatgcaga gtcaagatga gttggcagat atcatttatg aattcagtag tctcttgcgt
    13021 aacaatattt ccgacgaaag agagaccctc ctcaaacagg aattagaatt ttgccgtaaa
    13081 tacagctatc tctgcatggt tcgctatccc aagtccattg cctatggttt caagatagat
    13141 ccagagttag agaatatgaa gattcccaag tttaccttgc aaccgctggt agaaaactat
    13201 ttcgcgcatg gtgttgacca caggcggaca gataatgtga ttagcatcaa ggctcttaaa
    13261 caggatggtt ttgtggaaat tttggtggtc gataatggta gaggaatgtc ggctgaaaag
    13321 ttggcaaata tccgagaaaa attaagtcag agatattttg aacaccaagc cagctacagt
    13381 gatcaaaggc agtctatcgg gattgtcaat gtacacgagc gttttgtgct ctattttgga
    13441 gaccgctatg ccattactat agagtctgca gagcaagccg gtgttcagta tcgtattaca
    13501 attcaagatg agtagaaagg gagaaaatgt ataaagtatt attagtagat gatgagtaca
    13561 tggtgacaga aggtctgaag cgtttgattc cctttgataa gtgggatatg gaggttgtcg
    13621 caacagccag tcatgccgat gaagctctag aatatgttca ggaaaatcct gtcgatgtca
    13681 tcatttccga tgtcaatatg ccagacaaaa cagggcttga tatgattcgg gagatgaaag
    13741 agatcttacc agatgctgcc tatatcctgc tctcaggtta tcaggagttt gattatgtaa
    13801 aaagagcaat gaaccttagt gtggtggact atttggtcaa gcctgttgat aaggtagagc
    13861 tgggaaatct gctggagaag attgcaggtc agctcggcga gagagggaag aaaagtcaga
    13921 ctcttagtca agaattagac gaggctggat ttgttagtta tttaggggat aaggagaatt
    13981 ggtggatagg tctatccaag gaaaaacaag gttccttcac cattccctac tatgtcttgg
    14041 gccaagactg gcagattttc atttctggcc aacctctaga tggtttagtc gttacacctt
    14101 ttgaagctcc ttatcaagaa cactttgaac gctggaagct gaatgctgag aaaaccctct
    14161 tttacggttc tgtaaatttg cagcagtctg agagtctctt tgcctattac gaaccgattt
    14221 atagggttat cattcaggga aatctcaatc aaatcgtaga agagttaaat ctcttggaga
    14281 aggtagttct tgaaaatacg ccgcgtgttc cgattactaa acagcttttt attcagtttg
    14341 tcatggatgt tttccattta tttgaacatc tcaaagctga tgacctgaca gacatcgtca
    14401 aaaccattca tgctattcaa tccttcgatg aattggtttc ttatatcaag gaaactctga
    14461 tcagcttttt cggtcaatac cgtatgaatg aaaatgtggt cagtgtgctg gaagtcattg
    14521 gtcgtgatta ccaaaaagag ctttccctca aggatatcag taaggctctc tttatcaatc
    14581 ctgtctatct agggcagttg attaagcgtg aaaccgattc gacctttgca gagttactaa
    14641 acaaacaacg tattaaggct gcccaacaac ttttgctttc aactagtgac agcatcgaag
    14701 atatttgtta tgctgttggt tacagtaacc ttggatattt ctataaagtt ttccgaaaat
    14761 tgtgcggaaa atcgccaaaa gcctaccgaa aacaggtaga aactatacta taaaatttgt
    14821 attcctttac aaaaggtgct ataatattat caggaggttc tatcatgaaa aagaaaccaa
    14881 tttatctatg ggtcttgcta atcttgtctg cccttatttc agttccgtct ctgtttggaa
    14941 ttgtgagtcc cttgcctagt aaggaagccc ttcgtgctgc tcagaaacaa gttgcagggg
    15001 tcaatgctca gcaattagaa gaccagctta attataccta tagagtagca gaagcatctc
    15061 attctatttt taatgttgct ttgattgtgc tatctactat tttagtggtc gtagcgattg
    15121 tcttccttgt tcgtaaaaat ttgcaatatg caaactatac ttacgttggc tatgttttgt
    15181 tagctattat tggttcgatt tatggctatg ttggtttaca agacgctgtg cagttggttc
    15241 aagatgagag catgcgtttg acagtgagta ttggttcaaa agctgttagc attttctata
    15301 tcgtcatcaa tgttctcttc ctagcccttg tcttctataa gatgtggcga caacagaaag
    15361 ccttggcaga agaagaggaa acagaagagc ttgcctaagt attgacaaaa aagaactatc
    15421 aagatacaat cttggtagtt gttttttgat tatagataaa atcatggagg tacatatgaa
    15481 gacaatttct ttagtttata ttagtttgag tggcaacact gaaagttttg tgacgcgctt
    15541 gaaagactat ctcttgtccc agtacaaagg gattgaggtt caaaagattc atatcaagga
    15601 tttagtcaag gaaggcaaaa atttctatga aatggaccat ccctatgtcg cttttttgcc
    15661 gacctatctc gaaggtggga atggcgtgga taacggagat gttgagattt tgacgacacc
    15721 ggtgggagat tttattgcct atggtaacaa tgctagtaag tgttttggtg tggttgggtc
    15781 aggaaatcgt aactttaata accaatactg cctaacagcc aagcaataca gtcaacgctt
    15841 tggctttcct gtattggctg actttgaaat gcgaggcatg ctggaagata tcaaacatgt
    15901 cgcagctatt atcgcagatt tgtatgagtt ggaaaaggag aattaatact caatgaaaat
    15961 caaagagcaa actaggaagc tagtcgcagg ttgctcaaag cacagctttg aggttgcaga
    16021 tagagctgac gtggtttgaa gagattctcg aatagtataa agttcttata agaggtggtt
    16081 gaagttgttc aactgttttt tgagtataaa cagtctttaa gaacgtaaaa aagcataagt
    16141 tcaggtcttc aaaaccttgt tcttatgctt tttatcatag aaatatttgc tgaattttct
    16201 cttgaaatga aaccttatct tcatctcgcg cttgtccctt accctgcttt tccgattgcg
    16261 agtgcgtaga taaagaagat ggcgaagcca aagaggaaaa tcaatcccgc aatggcaagg
    16321 tgtttgagcc aagaaggaag atttttgttt tcacgcgtta ccaaggcgta attcaaaaga
    16381 gcaaagaaag gtgttgtcag gaaagagcca atcatggcaa agcggagcat ggttgaaacc
    16441 tgaccagcga agaacttgat aatgacgata ccgatgatag cagtgatggt catccagatg
    16501 ttcaaagatt tacgattgtc ctctttttga ctgattagca gtcggagaga ttcctgatta
    16561 acgcgagaat agccatcgat aacagttata actgttccaa agatacagag gaaggcaata
    16621 aaggtaatca agtaacggga ccattcgcca agaacagagg catacatgcc cacgaattga
    16681 gagatgtatt tggctgaagc agcttcaacc gcctgccctg taggatactg aatcagtgct
    16741 cccagtgcca caaagaagac ggctaggata gctgttccaa tataaccagt gttaaagtca
    16801 aacacagcgt cttctgtgtt aaagttgacg gtctttctct tttcagctga ccaaagtgaa
    16861 ttgatggctg aaatttcaat aggagccggc atccatccta ggagggagac gatgaagggc
    16921 agagctgcca tttgccaagg tgtcttctcg acaaaatcag aactgtattc tggatgcttg
    16981 accgccgcaa tgataactgc aagaacagtc gcaatggtta aggcagacat aatccatttg
    17041 accatgccgt ctaaaagttt gtagcctcca aagagtagca tagcccaaat gattgcaacg
    17101 agaatgaggg accactgagt aatgctaagt ccaatcattg ggaaggcact ggcgatgata
    17161 gctgagcaca gaatggcaac accagccgtg ttgaccatag ccgaaaagac attgaggata
    17221 aagaaaatcc agagatagag ttttcctttt tcggcataac cttcaaccaa agtctttcca
    17281 gtatcagctg tgtattcagc accaaaacgg aaaaatggat atttaaagac attggctaag
    17341 atgaccaaga gaagtagaga ccaaccgtaa gaaccgccag cttgagttga ggatacaatg
    17401 tgggaacctc caacagcggc agttgccatt aggattccag gtcccattgc ttttagcttg
    17461 cttgcccagg ttgattgatt taaggaaata gcttgcgaca tgataaatac tcctttttga
    17521 attttcagaa taatctgtat atgtaatcta tattctacaa aaaattttgg aaaaatgcaa
    17581 gagtattttg aaaaaagata gaaaatttac aaagaaaatc tgaaataact gttatgatat
    17641 agcagattga aactagaata gtacactttt gcttctaaaa cattgttaga aatcgatttg
    17701 actgtcctga ttgatttacc ctgttcttat ttcatttcac tatagtaagg tgcagcagga
    17761 taaagcaaaa ccgagaagtt tctttctcgg ttttgcttat tatgaggttc ctattttcta
    17821 tgctccaaga gttgattgat gtgatctact tttttagcct ctcttttata gagaatagcc
    17881 cagatgatga gatagacaat cgcaaactcg ataatgagct ggaggtagaa aatccagtgg
    17941 aaggggaacc aaccagcaag agttgctagt gggacaaagc cagccagcat aaggaagaaa
    18001 tgagtcagag tggcacgaag catgctccag tcacggctga ataagcggtt gccaaagttg
    18061 aagagcatac cgatggctgc ccagataagt gtgcagtaga gcaagaccag ggcaccgtga
    18121 acctgatgct gatccatcac ttggccgatg agagagtagg gatttagtgg tgcgtaggta
    18181 tttggtgcat aaatgagtga aaagaggatg gagaggatga ggccgataag aacaccggca
    18241 gctgcatcgt gaaatacttg ttttttcata gttctaattt ctccttgatg gtttttagat
    18301 aacggcgtga agagtaggtg aagctttcgt ttttcaagaa aatttctacc agaccgtttg
    18361 gcgtgagctt gaggtgagag atggaatcga tattgatgat ttctgattgg gaaatttgga
    18421 taaaattggt tggcaagagt ttaagaacct gatagagtcg caaatcaatg ctgtaggtct
    18481 gactcgcggt ttctgctaga accttccgat tctcgatata gaagcgctga atcttgccaa
    18541 tctcaactag atagacctga tcatcgattt ttcctttgat tttttctctt tggtccagat
    18601 tttctgcgaa ctcgatgact ttctggactt tttcggtttc ttgaggtgct tggacaatca
    18661 gcttttcctc ctcgtaagtc tcactaatct gtagttctac tttcataaat ttctctcctt
    18721 gtttttcata caaaattaat ctcacttctt gtacaccttt attaatactc ttcaaaaatc
    18781 tcttcaaacc acgtcagcgt cgtcttgccg taggatagtt gttgactttg tcagttttat
    18841 ctacaacctc aaaacagtgt tttgagctgt ctgcgtctag ctttctagtt tgctctttga
    18901 tttttattga gtataccact attttactcc ctctggcaag ggactttgtc tatgtggagg
    18961 gattgggctc ctatgtggtg gagtttttct gttctttctg aaatatggta taatagcact
    19021 aattaatttc taggaaaata gatacagaaa ggggctgaaa gatgtctcat attattgaat
    19081 tgccagagat gctggcaaac caaatcgcag ctggggaggt cattgaacgt cctgccagtg
    19141 tggttaaaga gttggtagaa aatgccattg acgcgggctc tagtcagatt atcattgaga
    19201 ttgaggaagc tggtctcaag aaggttcaaa tcacggataa cggtcatgga attgcccacg
    19261 atgaggtgga gttggccctg cgtcgccatg cgaccagtaa gataaaaaat caagcagatc
    19321 tctttcggat tcggacgctt ggttttcgtg gtgaagcctt gccttctatt gcgtctgtta
    19381 gtgtcttgac tctgttaacg gcggtggatg gtgctagtca tggaaccaag ttagtcgcgc
    19441 gtgggggtga agttgaggaa gtcatcccag cgactagtcc tgtgggaacc aaggtttgtg
    19501 tggaggatct ctttttcaac acgcctgccc gtctcaagta tatgaagagc cagcaagcgg
    19561 agttgtctca tatcattgat attgtcaacc gtctgggctt ggcccatcct gagatttctt
    19621 ttagcttgat tagtgatggc aaggaaatga cgcggacagc agggactggt caattgcgcc
    19681 aagcaatcgc agggatttac ggtttggtca gtgccaagaa gatgattgaa attgagaact
    19741 ctgacctaga tttcgaaatt tcaggttttg tgtctttacc tgagttgact cgggctaacc
    19801 gcaattatat cagcctcttc atcaatggcc gttatatcaa gaacttcctg ctcaatcgtg
    19861 ctattttgga tggtttcgga agcaagctta tggttggacg ttttccactg gctgtcattc
    19921 acatccatat cgacccttat ctagcggatg tcaatgtgca tccaactaag caagaggtgc
    19981 ggatttccaa ggaaaaagaa ctgatgaccc tggtttcaga agctattgca aatagtctca
    20041 aggaacaaac cttgattcca gatgccttgg aaaatcttgc caaatcgacc gtgcgcaatc
    20101 gtgagaaggt ggagcaaact attctcccac tcaaagaaaa tacgctctac tatgagaaaa
    20161 ctgagccgtc aagacctagt caaactgaag tagctgatta tcaggtagaa ttgactgatg
    20221 aagggcagga tttgaccctg tttgccaagg aaaccttgga ccgattgacc aagccagcaa
    20281 aactgcattt tgcagagaga aagcctgcta actacgacca gctagaccat ccagagttag
    20341 atcttgctag catcgataag gcttatgaca aactggagcg agaagaagca tccagcttcc
    20401 cagagttgga gtttttcgga caaatgcacg ggacttatct ctttgcccaa gggcgagatg
    20461 gactttacat catagatcag cacgctgctc aggaacgggt caagtacgag gagtaccgtg
    20521 aaagcattgg caatgttgac cagagccagc agcaactcct agtgccctat atctttgaat
    20581 ttcctgcgga tgatgccctg cgtctcaagg aaagaatgcc tctcttagag gaagtgggcg
    20641 tctttctagc agagtacgga gaaaatcaat ttattctacg tgaacatcct atttggatgg
    20701 cagaagaaga gattgaatca ggcatctatg agatgtgcga catgctcctt ttgaccaagg
    20761 aagtttctat caagaaatac cgagcagagc tggctatcat gatgtcttgc aagcgatcta
    20821 tcaaggccaa tcatcgtatt gatgatcatt cagctagaca actcctctat cagctttctc
    20881 aatgtgacaa tccctataac tgtcctcacg gacgtcctgt tttggtgcat tttaccaagt
    20941 cggatatgga aaagatgttc cgacgtattc aggaaaatca caccagtctc cgtgagttgg
    21001 ggaaatatta aaagtataaa aaagtctggg aaaaattttc aaaatcagaa aaacgcataa
    21061 aatcaggtgt tcaaaaacct tgattttatg cgttttatca tagaaatatt tacttcatgt
    21121 tttcctaatt cttttcgaaa ctctttttaa accacgtcag ttttatcagt aatctcaaaa
    21181 cagtgttttg agctaatttt gccagttttg tctgtaacat cgaagttgtg tttgaccact
    21241 ctgcgactgg tttcctagtt tgctctatga ttttcacaga gtattaaatt gcgattttgc
    21301 caagtttctt tattcgtcta aaagtagagt ctgttctatg cgtctaatgt acgaattagg
    21361 ttgaccattt caatagctcc ttgtgcacac tcagaaccct tatttcctgc tttagtgcca
    21421 gctcgttcta tggcttgttc aattgtatct gtcgttagca caccaaacat aacaggaatt
    21481 tcgctattta aactgatttg ggcgattccc ttagatacct cgctacatac ataatcataa
    21541 tgacttgtat tccctctaat gacagctccc aagcagataa ttgcatcata ttttttactt
    21601 tttgccattt ttgatgcaat cagtggtatt tcaaaagctc ctggaaccca ggctacctct
    21661 atatctttct cgtttacatt ctctcttttg agattatcta gtgctccaga taataatttt
    21721 gaagttataa attcattaaa tctcgctaca acaataccta ttttaatatt gtttgctact
    21781 aaattacctt cataagtgtt catttatttt tcctccatat ttaaaatgtg acccattcga
    21841 tttttctttg tttctaaata aaaactatcg taaggattgg cttctatttc gattgatatt
    21901 ctactggaaa tggtaattcc atatttttct aactgttcaa ccttgtcagg attatttgtc
    21961 agtaaatgaa gtgactgaag tcccagatct ttaagcattt gtgctccaat atgatattct
    22021 cttaaatcac cttcaaagcc taatgcaaga ttggcatcaa gcgtatccat gccttgatct
    22081 tgtaaatgat aggcttttaa tttattgata agtccaattc ctcgtccctc ctgtcgcaag
    22141 taaagtaaga cacccgaacc attctcaaca atcattttca tagctttatc gaattgctgt
    22201 ccacaatcgc aacgtaagga gcctaaaaca tcccctgtta aacattcgga gtggacccga
    22261 cataatacat tggcttcatc ctctatgttt cccataataa gagcaagatg atgttcccca
    22321 tttagtttat ctatatagct aattgctttg aaattaccgt atctagtagg catattgaca
    22381 gttgaaactc gttctaccag ctgatcatat acttttctat attcttgtaa ttctttgatg
    22441 gtaattagtg gaatgttgtg tttcttcgag aactgaatta aatcatctgt tctcatcatt
    22501 ttgccatcat gattcattat ttcacaacat aggccacact cttttagtcc agctaatttt
    22561 aataaatcaa cagttgcttc tgtgtgtcca cttctttcta gaacaccacc tttttttgca
    22621 attaaaggaa acatgtgtcc tggcctgcga aaatcagagg gtgttatatc ttcagctaca
    22681 cacatacgtg cggtcagtcc tctttcctcg gcagaaatac ctgtggtcgt ttctttataa
    22741 tcaattgaaa ctgtaaaagc agtcttatga ttatctgtat tgttttcaac cataggtgaa
    22801 agcattaatt gattagctaa actttcgctc ataggcatac aaattaatcc tttggcataa
    22861 gtagccataa aattaacatt ttctgttgta gctgcttgtg cagaacaaat taagtctcct
    22921 tcattttctc tatccttgtc gtctataaca agaacaagtc gtcccttctg caatgcttct
    22981 aatgcttctt gtatttttcg atattccatt gactgattat cctttctgct aaaatccatt
    23041 ttgatataat agttccttag atatttctga ttttggagag ttatccatca gtttttgcac
    23101 atatttacct aagatatcat tttcaagatt tactgtactc ccgacttgtt tactcttaag
    23161 aatggtttgt tccaaggtat gagggataac agatactgaa aagtttactt tggagacttt
    23221 agcgacagtc agactaatgc cgtcaattgt aatagatcct ttttcaacta ttaaatctaa
    23281 aatttctttt tgtgtgttga tttgatacca tacagcatta tcatcttttt ttattgacga
    23341 gatttttcct gtaccatcaa tgtgtcctgt aacgacgtga cccccaagtc gaccgttgac
    23401 agataaggct ctttctagat tcacctcact tccatgtttt aatagagtaa gagctgttcg
    23461 actccatgtt tcattcatta catcaactgt aaaggattga tgattgaaat gagtaactgt
    23521 aagacagata ccatttactg ctatactatc gcctaaatgg atatccgtta atatttttga
    23581 ggctttaatt gatagtttac aattacgaga gtctttctgt attctttcaa cttttccgat
    23641 ttcttcaatt attcctgtga acatggataa atcacttcac tttctatgag atagtcattt
    23701 cctatttgag aaaatgcata aggtttcaat ctaatagcgt catttggcaa agaaatacct
    23761 tcacctccga caggaaactt ggcactacct ccaaaaattt ttggtgcaat atatattttc
    23821 agctcatcaa caatttgttg ttccaaagca ctccaattca ttagactgcc cccttctaga
    23881 actaggctat caatctgcat gtttcctaga tgttgcatta aactcgataa gtctatatga
    23941 ttgccttttt tctttatgga aagtatttca cagccatgat tttgatatag cttcatttta
    24001 tttttgtctt cagaggaagt ggcaatgtaa gttttaatat catttgctgt ttttacgatt
    24061 ttagaggtaa gaggagttcg taaatgtgta tcgcatatga tacggatagg atttttccct
    24121 tcctccaatc tacatgtcag caaaggatcg tcttgaataa cagtattgac tcccaccata
    24181 attgcactaa catggtgtcg taactgctgc acatgctttc ttgcttcttc ttcagtaatc
    24241 catttggatt gatttgtttt agtggctatt tttccatcca ttgacattgc atatttcata
    24301 aaaacatagg gtacatgctg ggtaatatac tttctaaaac tttttattaa gttaagacac
    24361 tcattttcta aaattccaac agtaacttga agattatttt cctcaagtat ctttactcct
    24421 tttccagata caataggatt acagtctagg cttccaatga ctactcttgt aataccacta
    24481 tcgattatag catctataca gggaggtgtt ttcccgaagt gacaacaggg ttcaagtgtt
    24541 acataaagcg tcgctccgac aggggattct ctacagtttt taagagcatt tctctcagca
    24601 tgtgggccac caaaaaactc atgataacct tgtccgataa tgtgattatc ttttacaata
    24661 actgcgccga ccataggatt gggattgacg taaccagccc ctttttgtgc cagttttatt
    24721 gctaatttca tatattttga atcgctcatc tcactacctc caaaaaaata tgccttgaat
    24781 aggggactac tcaaggcata caaaagaaaa cttatgcgat taacaaaaat gctctgaaat
    24841 gacaagtaat catttcagag cacgcaaaaa gcacaaatat acttttatct tctttcatcc
    24901 agactatact gtcggctttg gaatttcacc aaatcatgcc tttcggctcg tgggctatac
    24961 caccggtagg gaattgcacc ctgccctgaa gatagttatt caattacaga tgattatagt
    25021 acttaatttt gaatatgtca acagataaat accgattgtt tttgatatac tgtatttgtg
    25081 ataatcgatt ctcgctcctc ggataaagaa aatatgatat actagataaa cgaaataaga
    25141 gagaaggaat actatgtacg catatttaaa aggaatcatt accaaaatta ctgccaaata
    25201 cattgttctt gaaaccaatg gtattggtta tatcctgcat gtggccaatc cttatgccta
    25261 ttcaggtcag gttaatcagg aggctcagat ttatgtgcat caggttgtgc gtgaggacgc
    25321 ccatttgctt tatggatttc gctcagagga tgagaaaaag ctctttctta gtctgatttc
    25381 ggtctctggg attggtcctg tatcagctct tgctattatc gctgctgatg acaatgctgg
    25441 cttggttcaa gccattgaaa ccaagaacat cacctacttg accaagttcc ctaaaattgg
    25501 caagaaaaca gcccagcaga tggtgctgga cttggaaggc aaggtagtag ttgcaggaga
    25561 tgaccttcct gccaaggtcg cagtgcaagc aagtgctgaa aaccaagaat tggaagaagc
    25621 tatggaagcc atgttggctc tgggctacaa ggcaacagag ctcaagaaaa tcaagaaatt
    25681 ctttgaagga acgacagata cagctgagaa ctatatcaag tcggccctta aaatgttggt
    25741 caaataggag cagagaatga caaaacgttg ttcgtgggtc aagatgacca acccgctcta
    25801 catcgcctat catgatgagg agtggggcca gcccctccat gatgaccaag tattgtttga
    25861 gttgttgtgt atggaaacct atcaggcagg cctgtcttgg gaaacggtac tcaacaaacg
    25921 ccaagctttc cgagaagtct ttcatagcta tcaaattcac tcagtcgcag agatgactga
    25981 cactgaattg gaagccatgc tggagaatcc agctatcatt cgaaatagag ccaagctttt
    26041 tgctacacgc gctaacgccc aagtctttct acagttacag gcagagtacg gctcttttga
    26101 tgcctatctt tggtcttttg ttgaggggaa aactgtcgtt aacgatgttc ctgattatcg
    26161 ccaagcgcca gctaaaacac ccttatctga gaaattagcc aaagatctca aaaaacgagg
    26221 cttcaagttc acaggcccag tcgccgtatt gtcttttcta caggctgcag ggctagttga
    26281 tgaccacgag aatgattgtg agtggaaagg tcttaaatga tgtctaacaa aaataaggga
    26341 attctgattt ttgcgattct ctatacagtc ctctttgtgt ttgatggcgt taaattgctg
    26401 gcttctttaa tgccatctgt cattgcaaat tatcttgttt atgtagtttt agctttatat
    26461 ggctccttct tgttcaagga tagattgatc caacaatgga aggagattag aaagactaaa
    26521 agaaaattct tctttggcgt cttaacagga tggctctttc tcattctgat gactgttgtc
    26581 tttgaatttg tatcagagat gttgaagcag tttgtgagac tagatggaca aggtctaaat
    26641 cagtctaata ttcaaagtac ctttcaagaa caaccactac tgatagctgt ttttgcttgt
    26701 gtcattggac ctctggtaga agaattattt ttccgtcagg tcttattgca ttacttgcag
    26761 gaacggttgc caggtttact aagcattatt ctggtaggac ttgtttttgc tttgactcat
    26821 atgcacagtt tggctctatc agagtggatt ggtgcagttg gttacttagg tggaggcctt
    26881 gccttttcta ttatttatgt gaaagaaaaa gagaatatct actatcccct acttgttcac
    26941 atgttaagca acagcctctc cttaatcatt ttagctatca gtatagtaaa atgaaataag
    27001 aacaggacaa atcaatcagg acagtcaaat cgatttctaa caatgtttta gaagtagagg
    27061 tgtactattc tagtttcaat acactgtaac atgtgatgaa aatgccagta atgataccga
    27121 gaaaaaagct gagaaacttt tcccagcttt atttgttata gtcaaagcga atgacttgtt
    27181 cctgtgcatc tacatgagca tggaccccaa agggtacaat tgctcttgga gttgcgtggc
    27241 cgacattcag attatagaca atcgggatat tgctgtcaat gatatctaat agtgcctctt
    27301 tatagtcgtc atggaaagtt tcatccatag gttttccgac caagagtcca ttgatgaccg
    27361 cgaatatgcc agtgtccttt aaagttagca acatcttttt gaagtcttct ggcttaggct
    27421 tttcttcgct tgtttcgagc aagaggattt tcccttccca gtctgacaag tcagggaaaa
    27481 gtttgtattt tgggcagagt tccgtgctat ctgcgtatcg agagttgtca aagatatcgt
    27541 agagggattc gaggcaacca ccgaggattt tcccctcgaa ctgagcactt ccttgcaaca
    27601 agtcaaaacc tgtatttgta tgactgacac gaggtgttcc cagggccgtg ggactaaaat
    27661 cagttcgttc ctcataccaa acgtcactag ggcggatttc tgaaattctt cccgtctcaa
    27721 tcaattcttt aaagtagtga aggctatagg ctagcatttc tttgtctaat tcacaaatgt
    27781 ctgctaaaaa ggattgacca taaaaagtct tgattcctaa tttatgcaac atgaggtggt
    27841 tcatggttgt atccgagaag ccaagaaaaa ttttttgctt gataaccttt tggagttggt
    27901 cattttcaaa aagataaggt agcaagcgat aggtatcgtc tccaccgatg gcacatagga
    27961 tcatgtcgat gctatcatca gaaaaggcat gaatcaaatc ctctgcacga gcttcaggat
    28021 ggtccttgat aaagtctaat ccttttaacg aatggggcaa aaagatggga ttgagtccca
    28081 gatccttgag acgttggata cccaagtcca cttcgtgttt gacaaaatcc tctccgataa
    28141 tgccactaga taaactaaca ataccaatag tagaaaccat atctcatcct cctagaaata
    28201 gattgagcct attttatcac aaaatataag agaaagctat gtgggatttc agaagaatac
    28261 ttttaatact cttcgaaaat ctcttcaaac cacgtcagtt ttatctgcaa cctcaaagct
    28321 gtgctttgag caacctgcag ctagcttcct agtttgctct ttgattttca ttgaatataa
    28381 ctcaaaaaag taagtgaaaa agcaaccgca cctgcagttg cttttatcgt tttcttattc
    28441 ttgatagcgt gttggtcctg cacttgcact acggatattc aagcgtttct tgagatagaa
    28501 gcgaagggct aggagggctg ctccaataat agctagtggc aatggatcca gtactgggtt
    28561 aaggctagct ggtaggaagc ttgttgcaaa gaagacaagc aaccaaagga acatagaagc
    28621 taggataact agtacagatt tccagaaagg tggacgttga ctgcgatcca tatctggtcc
    28681 atagtattgg taaacaaagt agtacatcaa gtagaaggca aatccaccaa ccagtccaac
    28741 taatagaaga gtaatcaatc catagccgaa agcttgatct gccgcaaaga aggttgtgag
    28801 ggcgctgaca agggcaaaga ggctagtgat gaaaagagct gagtccataa tcatcagttt
    28861 tggatcatca ttttcttttg gatgctcttt ttcgtactgc tctttgacag tgaagctatg
    28921 agcccaatga gttggtgcgc cgtataggga acgggcagtt gtacctttag attgctcctc
    28981 aaggatttgg ggaatgactt cctcaaaaat agtctggatt tcagcgtctg ttttcccatc
    29041 tttgatgaat tgttgggtag caatgtggac aaactcttgg tttttcttag ttaatttttg
    29101 tagatcaatt tgagacatag gaactcctct tagaaccatt ttttatggat gagatagaga
    29161 gtgagcgaga cactcatagc aaaggcgata aagacgatta accagaaggc atttggctct
    29221 ccgtttaggg ggatttcatt atccttaaag ttcatcccgt aggcagaaaa gaccatggtt
    29281 gggatggaca tgacgatggt cacaagggcc aaggttttca tgatgttgtt ctggttgtta
    29341 gaaatgatag aggcaaaggt ctctgtcata gaatgcaaga cgtttccata aatatctgcc
    29401 atctcgatgg cctgttgggt ttcaatcagg gtgtcttcaa gcaggtcttc gtcctcaagg
    29461 tatttcttga tattgctggt tgaactggtc aatttcttaa tcacgcgctc atttgttttg
    29521 agggaggcct tgaaatagac gatagttttt tccaattcca tgagctcaat caattcttca
    29581 ttacgagttg attgatgcag ttgactttcg atttgttcac tcttgcggtc gattgaacga
    29641 agggctgtta ggtaaagctc tgcattgcga taaagaattt gaaagataaa acgtgaacgc
    29701 atgaaggtat agaaattacg caatcgacgg ttgataaaga catcaaggac aggtagtggt
    29761 tccaaacacg tagtgataat ggtttcctca gtgatgataa taccaagcgg gatggttacg
    29821 tagtaggtgc ggttatttct ttcctccgtg accggcacgt ctacgataat cagggtatac
    29881 tcgtcttcaa tggtaatacg agacatttct tccgcatcga gcggtgctcg aaggtcggca
    29941 atatcaatat cgaaggtgtt ggcgatttcg agtgattcat tttgagtcgg attgacgaga
    30001 ttgatccaag tacccggttc aagcgtatcg atctctttaa attcagttgt tgtagagaga
    30061 aaaacttgtt tcatatccct tatcctttct catttttcag attttttcac actgtactat
    30121 tatactacaa aatcggcctt ttgggtaata gaatctcact ttttttggta taatggtaag
    30181 caataatgga ctagaaagaa caaagatgca agataaaatt gtcattcatg gggcgcgtgc
    30241 ccataattta aaaaatattg atgtggagat tccgcgagac aagctggttg tcgtgacagg
    30301 tttgtcaggt tcagggaaat ccagtctggc ctttgatacc ctctatgcgg agggacaacg
    30361 tcgctatgta gagagtttgt cagcctatgc tcgtcaattc ttaggaaata tggagaaggc
    30421 ggatgtggat gccattgatg gtctcagtcc agctatttct atcgaccaga aaacgactag
    30481 caaaaaccct cgctcgacgg tgggaacaac gactgaaatc aatgactatc tgcgtctcct
    30541 ctacgcacgt gtggggacgc cttactgtat caacggacat ggagctatca atgcttcttc
    30601 tgtggagcaa atcgttgata aggttttgga gttacctgaa cgccagcgct tgcagatctt
    30661 ggcccctgtc atccgcaaga aaaaaggcca acataagagt gttatcgaga aggttcagaa
    30721 agacgggtat gttcgtgtcc gtgtggatgg ggaagtctat gatgtgaccg aagtgccaga
    30781 gttgtctaag agcaagcaac acaatatcga tgtcgtggtt gaccgtattg ttatcaagga
    30841 gggcattcgt agtcgtctct ttgattccat tgaggctgcc cttcgtattg cagaaggtta
    30901 tgtcattatc gacaccatgg acgactctga gttgttgttc tctgagcatt atgcctgtcc
    30961 agtttgtggt tttactgtcc cagagttaga gcctcgtctc ttctctttca atgctccttt
    31021 tggctcttgt agtgagtgtg acggcttggg catcaagctg gaggtggata ctgatttggt
    31081 agtgccagat gccagcaaaa ccttacgtga gggagcgtta gcaccttgga atcctatctc
    31141 atccaactac tatccaaaca tgttagagca ggccatgaaa gtctttggag tggctatgga
    31201 taagcctttt gaggacctgt cagaagaaga taagaacttg attctctatg ggtcagatgg
    31261 taaggaattc catttccact atgagaatga atttggtggc gtgcgcgata tcgacattcc
    31321 gtttgaggga gttatcaata atatcaaacg tcgttaccat gaaaccaata gcgattacac
    31381 tcgcactcag atgcgtctct acatgaatga gctgacctgc ggaacctgtc aaggctatcg
    31441 tctcaatgac caggccttgt ctgtccgtgt gggcggccag caagggccac atattggaga
    31501 aatctcagac ctgtctatcg ctgaccactt ggacttggtg agccagttaa ctttgtctga
    31561 aaatgaagcc atcattgctc gtcccattct caaggaaatc aaggatcgtt tgaccttcct
    31621 taataatgtg ggtcttaact atctaaccct gtcacgttca gcaggaaccc tttcaggtgg
    31681 ggaaagtcag cgcattcgtt tggcaaccca gattggttcc aacctatcag gcgtcctcta
    31741 tatcctagac gagccgtcaa tcggtcttca ccagagagac aatgaccgcc tgattgccag
    31801 tctgaaaaag atgcgtgact tgggcaatac tcttatcgtg gtggaacacg acgaagatac
    31861 catgcgtgaa gctgattatc tgattgacgt tggtcctggt gccggtgttt ttggtggtga
    31921 gattgttgca gcaggtacac ctaagcaagt ggctcgcaac agcaagtcta tcacaggtca
    31981 gtacttgtca ggcaaacgtg tcatcccagt accagaagag cgccgtgtcg gaaatggtcg
    32041 ttttattgaa gtgataggag cgcgtgagaa caacttgcaa aatgtcacgg ctcgctttcc
    32101 actaggaaaa tttatcgcag tgacaggtgt gtcgggttca gggaaatcga ctctaatcaa
    32161 cagcattctt aaaaaagcca ttgcccagaa gctcaaccgt aattcagaca aacctggtaa
    32221 gtttaagact attacaggga ttgagcatgt cgaccgtttg attgatattg accagagccc
    32281 tatcggacgg acgccgaggt ctaacccagc tacctataca ggagtttttg acgatatacg
    32341 tgaccttttt gctcagacaa atgaagccaa gattcgaggc tacaagaagg ggcgcttcag
    32401 tttcaacgtc aagggaggtc gctgtgaagc ttgctcaggt gacgggatta tcaagattga
    32461 gatgcacttc ttgccagatg tttatgtggc ttgtgaagtt tgccacggaa cccgctataa
    32521 cagtgaaacc ctagaagttc actacaagga aaagaatatt tcgcaggtct tggatatgac
    32581 ggtcaacgat gcggtagaat ttttccaaca cattccgaaa attcaacgca aactccagac
    32641 catcaaggat gtagggctag gctatgtgac cttgggacag ccagctacca ccctttctgg
    32701 gggagaagcc caacgtatga agttagctag cgaactccac aaacgctcga caggaaaatc
    32761 tttctacatt ctggatgagc cgacgacagg gcttcataca gaggacattg ctcgcctgct
    32821 caaggtttta gctcgctttg tagacgatgg caatacagtc ctcgtcatcg agcacaatct
    32881 ggatgttatc aagacggcag accatatcat tgacttggga cctgagggcg gtgtcggtgg
    32941 tggaaccatc atcgtaacag gaactccaga agaagtagct gccaatgaag ccagctatac
    33001 aggacactat ttgaaaggaa agttacatca tgaataaacg cgtacaagca tttctagcta
    33061 aaatgcaaga aaaagaacta gatggtatca tcatcaacaa tcttaaaaac gtctattatt
    33121 tgactggttt ttggggctca aacggaacag tctttatcag ccgtgaccgt caggtcttag
    33181 tgacagactc tcgctatatc atcgcagcta agcaagaaac cagtggtttt gagattgtgg
    33241 ctgatcgtga tgaattggct gtcattgcag gaattgttaa ggacatgggc ttgactcgta
    33301 tcggttttga agatgagatt tcagtatctt attaccaccg tatgcaggca gcttttgcag
    33361 gtttggactt gcttccacaa actcaatttg tggaaggtct tcgtatgatt aaggatgagg
    33421 cagagattgc agcgattcgc aaggcttgtt ctatctcaga ccaagctttc cgcgatgcgc
    33481 ttgactttat caaaccagga aaaactgaaa ttgaaattgc caacttcctt gatttccgca
    33541 tgcgtgagtt gggagcatct agcttatctt ttgatacgat cctagctagc ggtatcaatt
    33601 cttctaaacc ccatgcccat ccaatgcaca aaccagtgga gttgggagaa gccattacca
    33661 tggacttcgg ctgtctctat gaccactatg tcagtgatat gacccggact atctatctag
    33721 ggcatgttag cgatgagcag gcagagattt acaatacggt tctaaaagct aaccaagcct
    33781 tgattgacca agctaaggca ggcttaggtt tccgtgactt tgacaaaatc cctcgtgata
    33841 ttatcattga ggcaggttat ggcgactact ttactcacgg cattggccac ggtattggtc
    33901 tggatatcca tgaggaaccc tactttagcc agacttctac agaaactatt aagacaggta
    33961 tggccttgac cgatgaacca ggtatctata tcgaaggcaa atatggcgtt cgtatcgagg
    34021 atgatatcct gattacagag acaggttgtg aattattgac cctagctcca aaagagttga
    34081 tagtcattta gttgtttgtc aagaaaaaag tacgaaaatg acgaaaaaag tcaaaaaaaa
    34141 ttaaaaatag gtcgcaagtc ggatgttttt tatggtataa tagactaaac tgatagtaac
    34201 atgtagcgaa aggggtaggt acatgattaa aatttataca gtctcaagtt gtactagctg
    34261 taaaaaagca aaaacctggc tcaatgccca ccagttaagt tataaagaac aaaaccttgg
    34321 taaagaagga attacgagag aagaattact ggatattcta accaaaacag ataacggaat
    34381 agccagcatc gtttcgtcta aaaatcgcta tgccaaagcc cttggagtgg atattgaaga
    34441 tttgagtgtc aatgaagttc tcaatctgat tatggaaaca ccgagaattt taaagagccc
    34501 aatccttgta gatgaaaaac gcctgcaagt tggctacaag gaagacgata ttcgtgcctt
    34561 cctaccacgc tctgtccgta atgtagaaaa tgcagaagca cgtttacgtg cagctctata
    34621 aacatcaagg ctgggagcac ttcccagtct tattctattt taatttcaaa aagaaagaag
    34681 agagaaatga aaaaaatagt tcttgttagt ctagctttcc tttttgtcct ggttggttgc
    34741 ggacagaaaa aagaaactgg aacagctaca aaaacagaaa aggatacgct tcagtcggca
    34801 ttgccagtta ttgaaaatgc cgagaagaat acagttgtaa ccaagacttt ggtcttgccc
    34861 aagtcagatg atggtagcca gcaaactcaa accattacat acaaggacaa gacttttttg
    34921 agcttaacga ttcaacaaaa acgtccagtt tctgatgagt tgaagattta tatcgaccaa
    34981 catggagtgg aagaaactca aaaagctctt cttgaagcgg aggagaagga taagtctatc
    35041 attgaagctc gtaaattggc aggtttcaaa cttgaaacaa aactattgag cgcaacggaa
    35101 cttcaaacaa cgactagttt tgattttcaa gttctggatg tcaagaaggc ttcccagttg
    35161 gaacatctga agaatattgg tttggaaaat cttttgaaaa atgaaccaag caaatatatt
    35221 tcagatagat tggcaaatgg cgcgacagaa caatagaaaa tccaaataaa tagactgcct
    35281 gaattgtaga aggtaaggaa ttatgctata atggtactat tctaaggaaa gagggtgtta
    35341 gaatgggatt tactgaagaa acagtacgtt ttaaattgga cgattccaat aaaaaagaaa
    35401 ttagcgaaac tttgacagat gtttatgctt cgttgaacga taagggttac aacccaatta
    35461 accaaatcgt aggttacgta ttgagtggag accctgccta cgttcctcgt tataataatg
    35521 cacgaaatca aatccgtaag tatgagcgtg atgaaatcgt tgaggaattg gttcgctact
    35581 acctaaaagg acaaggagtc gatctataac ctatgagaat tatgggattg gacgtcggtt
    35641 caaaaacggt aggggtggcg attagcgatc cgcttggttt tacagctcaa gggcttgaaa
    35701 tcatccagat aaatgaagaa caaggccaat ttggttttga ccgcgttaag gaattggttg
    35761 atacttacaa ggtggaacga tttgtagtgg gcttgcctaa aaacatgaac aatacaagtg
    35821 gaccgcgcgt agaagctagt caagcctacg gagcaaagct agaagagttt tttggtttac
    35881 cagtagacta tcaggatgaa cgcttgacaa cagtggctgc tgagcgcatg ttgattgaac
    35941 aagcagatat cagtcgcaat aagcgcaaga aagtcattga taagttagca gctcagctga
    36001 ttttacaaaa ttatttagat agaaaatttt aatataaagg agaggctatg tcacacgatc
    36061 ataaccacga ccacgaagaa cgtgaactaa tcacactagt agatgagcaa ggaaatgaaa
    36121 ccttgtttga aatccttttg acaattgatg gaaaagaaga atttggtaaa aactatgttc
    36181 ttctagtacc agttaacgca gaagaagacg aagacggaca agttgaaatc caagcttact
    36241 cattcattga aaatgaagat ggaacagaag gcgaattgca accaatccca gaagactcag
    36301 aagacgaatg gaacatgatt gaagaagtct tcaacagctt tatggaggag taaaaacgtc
    36361 cgggggacgt ttttagccct gcgctagaaa ttagaaacgc aggtagtctg ggagactgta
    36421 tcagcccaac tccagaaatg gggaagagtt ggaacgtcca gtgaacattt ttaccccata
    36481 ttcacattca tagtagctag ttattagcta accaggtaag aggtcgggac gaaaatcctg
    36541 gccttgtttt tattagtaac catactttaa tgcgataatt gattggactt ttgtcaagga
    36601 gatgtgtatg tttgaagtag aagaatggct ccatagtcgg attggtttga attttcgatc
    36661 aggtttgggc cgaatgcagc aagcggtgga tttgttagga aatcctgagc agtcttaccc
    36721 tattatccac gtaacaggga ctaatgggaa aggatctacc attgctttta tgagggaatt
    36781 atttatgggg catggcaaaa aagttgcgac ctttacctcc cctcatatcg tctctatcaa
    36841 tgaccgaatc tgcattaatg ggcaacctat agcagacgca gactttatcc gtttgactga
    36901 tcaggtcaag gagatggaga aaacgcttct gcaaactcct gcccagttgt ccttttttga
    36961 attgctgacc ttagttgctt ttctttattt tagggagcaa gaggtggatt tggttttatt
    37021 agaagtggga attggtggct tacttgacac gaccaatgtg gtaactgaag agcttgctgt
    37081 catcacctcc attgggcttg accatcaaga aaccttgggt gatagtctag aagcaattgc
    37141 agagcagaaa gctggtattt tcaaggctgg taagaaggca gtgattgcga aattgcctcc
    37201 agaagctagg cttgtctgtc agaaaaaagc cgaatcttta gctgttaacc tttatcaggc
    37261 aggtcaagat tttttaatgc tgaatggtga tttttcaagc tctttactaa atctttcaca
    37321 gctgaacata ggcttagaag gagtctatca gcaggagaat gcagccttgg cgttgcaaac
    37381 ttttcttctt tttatgggag aaggaaagga agctgttgat gaacaggctg taagaaaggc
    37441 cttggaacag acccattggg ctggtcgctt ggagcgtatt cgcccacaga tttacttgga
    37501 tggtgctcat aacctccctg ccttgactcg cttggttgag tttatcaaag aaaaagagca
    37561 ggaaggctat cgacctcaaa tcctttttgg agccttgaaa cggaaggatt atcaagggat
    37621 gttaggttac ctgactgaaa aattgcctca ggtggaactc aaggtgaccg gctttgacta
    37681 tcagggggct ttggacgaaa gggatgtgac aggttacgat atagtttctt cttaccgaga
    37741 atttatcagc gattttgaag aaagagcaga tgctcaggat ttgctgttcg ttacagggtc
    37801 tctctatttt atctcagaag tacggggcta cctgctggac cgtgagcaga taaattgacc
    37861 cccttgtttg aacttgttat actaggggaa ttgctggtta gagaaaattt ctctaaattg
    37921 gtagcagaaa ggaaattcat catgaaatta aaaagattca cactttctct tgcttctcta
    37981 gcaagtttta gtctcttagt agcttgttca caaagagctc aacaggttca acagcctgtt
    38041 gctcagcagc aggtccaaca gcctgctcaa cagaatacca atactgcaaa tgcaggaggt
    38101 aaccaaaatc aagcggctcc agtacaaaac caacctgttg ctcaaccgac cgatattgat
    38161 gggacttata ctggtcagga tgacggagac cgtatcactt tagtggtaac tggaacgact
    38221 ggtacatgga ctgagctcga atctgacggg gatcagaaag tcaaacaggt tacatttgat
    38281 tcagcaaatc aacgcatgat tattggcgat gatgtcaaaa tttacactgt aaacggtaat
    38341 caaatcgtcg tagatgatat ggatagagac ccatcggacc aaatcgtttt aactaaataa
    38401 gactatgcaa gtagaaaggg ctggattttt cagccttttt acttttacct agaaaataat
    38461 cataaatact tgccttctac cgaatacctg cgttatacta gtatcaatta cttgttttta
    38521 gcattcaaac tatcaaggag gggatatgaa atataggaaa tttcaattat tgatgtccaa
    38581 gtatggcttt agtctttcga ttatgctact tgaactttgt cttgtttttg gtctctttct
    38641 ttatttagga cgcatggctc ccattttatg gattactgtc ctcattctac tgagtatcat
    38701 cacaatcatt tcgatagtca accgtaatac gactcctgag aataaggtaa cctggttgtt
    38761 agtagccttt gtgccagtat ttggtccctt gctctatctg atgtttggtg aaaggcgatt
    38821 gtccaaaaaa gaaatcaaac aactgaagaa gctaggctct atgcatttcc aagaagcaaa
    38881 tagccagcta ctaaaagaga aattaaaaga aagtgacaag gcagcttatg gagtcatcaa
    38941 gtccttattg agtatggata ccaatgctga catctatgat caaactgcct ctacattttt
    39001 tcctaacgga gaagctatgt ggaaaaagat ggtagaagat cttaaaaagg ctgagaaatt
    39061 tattttcttg gaatattaca ttatagaaga aggtttgatg tggaatcgca tactagatat
    39121 actagagcaa aaggtagctc agggtgtaga ggttaagatg ctctatgatg atatcggctg
    39181 tatggctact ttaacaggag attatgcaca tcgacttcgt cagctgggca tcgaggccca
    39241 taaattcaat aaagttattc ctcgtttgac agtggcttat aataacagag atcatagaaa
    39301 aatattgatt gttgatggtc agatagccta tactggtggg gtcaatctgg cagatgagta
    39361 cattaaccac gtcgagagat ttggttattg gaaggatagt ggaattcgct tagacggact
    39421 agcagtaaaa gctctgacac gcttattttt gaccacttgg tacattaatc gaggagaaat
    39481 tagtgatttt gatcaatatc atttagaaaa tcattctatc ccgagtgacg gtttaaccat
    39541 tccatacgga agtggaccca agccaatttt tcgagcgcag gtagggaaaa aagtttatca
    39601 gagtttaatc aatcaagcaa cagaatcggt ctatattacg acaccttatt tgattataga
    39661 ttatgattta acagagacaa tcaaaaatgc agctatgaga ggggtcgatg ttcgaattat
    39721 caccccttac ataccagata agaagttcat tcagttagtc acgagaggag cttatcccga
    39781 ccttctttct gctggtgttc ggatttatga gtatagtcca ggttttattc atagtaagca
    39841 gatgttggta gacgaagatt ttgcggtggt ggggacaatc aatctcgact accggagctt
    39901 ggtacaccat tatgaaaatg cagtcttact ctataaaact ccttctataa gggaaatcgc
    39961 ccgagatttt cgaaatatat ttgcagattc tcaggaagtc tatcctcatt ctatcaaaac
    40021 gagctggtat caaaagcttg taaaagaaat cgcccagcta ttcgccccta tcttataaga
    40081 aatctagaac ttaggataca aaccagacct atttttcttg tcttttacga atagaaagaa
    40141 agaggagggg aattcatgct aactaaggaa gaagtgaatg atatgattga gttcaaacgg
    40201 acacatttac accgctttcg ggaaattgaa acctttgtga aactatgcaa aaaatcactc
    40261 aaacagccat cgcaagctga caatcctagg actttttgat atactaagac agataaattg
    40321 aacaggagaa acgatatgag tgtgtatggt agagtagaag aagttcataa ggagaatcgt
    40381 gaacctctag aataccaaat cgaacaagaa tcgcatcatc gtgaatcaag tcgtcttcct
    40441 ttggtgaaaa ttttactatg gagtacgctt gtaacgggga taactctagg agtaccgcta
    40501 ttactcgact taatgagtgc acaagaagtg caggattttt atgcaggttg ggcgcttcat
    40561 cagacaggga agatttacag cgactattat ggaagtcaag gtttgcttta ttatttgctg
    40621 acttacgtga gtcagggcgg atttttcttt gccatctttg agtggttagc cttggtagca
    40681 ggaggatttt tcctttttag atcagcggac accttgacag agcaaggaga ccaagctgga
    40741 catctggtga ctatttttta catgctagtt acaggtcttg cttttggtgg aggctatgcg
    40801 actcttttag cgcttccttt cttattcgca gcctttagtt tagttgcggc ttacctaagc
    40861 aatccaagcc atgataaggg atttgtacgg attgggctag ctttggcagg cggatttttc
    40921 tttgctccct tatcatcgct cctgtttatt gctgtagtga gtttaggctt gttggtcttt
    40981 aaccttgggc atagacgttt tgtgcatggg ttttatcagt ttcttgcagt ggctttaggt
    41041 ttttcacttg tcttttatcc aactgcctac tatagtgctg caacaggaag ttttggggat
    41101 gcgattagtg gtattcgtta tcctattgac agtattcgct ttgattttac ttctaaaatt
    41161 ttagagaata tgttttttta tggcttgttg tcccttggtt tgggatttgt ggtttgtatc
    41221 tttttaggtc tctttcaatc caaacccttt aaactatacg tcatttcggt tcctgcaagt
    41281 cttgtggtaa ttttaggttt gattttactt ttcttttcac aagagcctct gcacgcttct
    41341 tatttgatgg tcgtcttccc tgttttccta cttttattgg taaccaatat taagagtcaa
    41401 cagagggggc gtagtgctag aagaagccga agagaaacgc cagttagcct atggagtcgt
    41461 ttcttcaaag gaaatctata tctgctagtt tttgggtttg tctatctttt gtctgttcct
    41521 tttttgatga agtttgtcct ttatccagta ccttatcaag aacgtaatcg tcttgctgat
    41581 ttggtaaaag aggagacaaa tacggaagat gctatctatg catgggatga tactgcgact
    41641 ctttatcgta agagtgagcg cttgtcgcca tcggcgattt tgtccccgtt gcactataca
    41701 gcaactgaag aaaatcgtaa taagttactt aatgacttga aagaaaaaca acctaaggtg
    41761 attgtggtaa atgacaaggt ggtagtctgg tctgaagtgg aaacactctt aaaagaaaat
    41821 taccaacaag taaagactga ttactcagag tttaaagtct ataaaattaa ataaccaaat
    41881 caatatcttg tgtattttta aaaattttag gatttttaac acaagatatt gatttttctt
    41941 tttagagtgg tataatactt tttagaaaga acattttaga aaagagcatg catatgattg
    42001 cactagaaga aaaaattaca attttgccaa ctctcttcgt cgagaaacga gatgggagac
    42061 gtgttgtatt tgatgtggac aagattgaca aggctctcca caaggcggct gacaaggtta
    42121 tggatgtgac acccttggtt gaaaaacgcc tcaatgatct gactgagcga attattacag
    42181 aaattcatag tcgctttcca cagggaatta agatttacga aattcaaaat atcgtagaac
    42241 atgaactcct tgaagccaaa gaatatgcgc tggctgagga gtatattact tatcggacac
    42301 agagggattt tgagcgctca aaagcgacgg atatcaactt tagtattcat aaacttctca
    42361 acaaagacca gacagttgtc aatgaaaatg ctaataaaga cagtgatgtc tttaacactc
    42421 agcgtgattt gacagcaggg attgttggga aatcaatcgg actgcaaatg cttcctaagc
    42481 acgtagccaa tgcccaccaa aagggggata tccactatca cgatttggac tacagtccct
    42541 atacccctat gaccaactgc tgtttgattg attttaaggg tatgttggaa aatggtttta
    42601 agattggaaa tgcagaggta gagagtccca agtctatcca gactgcgaca gcacagattt
    42661 ctcaaatcat tgccaacgtt gcttctagcc agtacggtgg ctgttcagct gaccgtatcg
    42721 atgaaatttt ggcgccttat gcagagaaga actatcaaaa acatctcaaa gatgcagaag
    42781 agtgggtatt gcctgaaaaa cgggaagatt acgcttggaa gaaaacgcaa aaggacatct
    42841 acgatgccat gcaatctctt gagtatgaga tcaatactct cttcacttca aatggacaaa
    42901 caccttttac ttcgttaggt tttggtctgg gaaccagtcg ttttgaacga gaaattcaaa
    42961 aagctatttt aaacattcgc atcaagggtc ttggttcaga acaccgtacg gctatctttc
    43021 ctaaacttat tttcactctg aaaagaggcc ttaatttaga ggaaggaact cccaactacg
    43081 acatcaagca gttggctctt gagtgtgcaa ccaaacggat gtatccagat gttttatctt
    43141 acgataagat tgttgacttg acaggatcct tcaaggtgcc tatgggttgc cgttctttcc
    43201 tccaaggatg gaaggatgaa aatggtgtag aagtcaattc aggtcgcatg aatctgggtg
    43261 ttgtgacggt taatctgcct cgtattgctc ttgagtctga aggtgatatg aataagttct
    43321 gggaaatctt caacgagcga atgaatatcg cagaagatgc tcttgtttac cgtgtcgaac
    43381 gcactaaaga ggcgacacca gcgaatgctc ctattcttta tcagtacggt gcttttggcc
    43441 atcgtctagg taaagaagaa agtgttgacc agctctttaa gaatcgtcgt gcgaccgttt
    43501 cgctgggcta tatcggcttg tatgaagtag cgacagtttt ctttggtaac agctgggaaa
    43561 gtaatccaga tgctaaggaa ttcacgctag acatcattca cgatatgaaa cgccgtgtag
    43621 aagagtggtc agaccaatat ggctaccatt tctctatcta ctcaacacca tccgaaagtc
    43681 tgacagaccg tttctgccga ctagatatag acaagtttgg ctctattcct gatatcacag
    43741 acaaggaata ctacaccaac tctttccact acgatgttcg taaaaatcca acaccgtttg
    43801 aaaaattgga ctttgagaaa gtctatccag aagcaggtgc gtcaggtggt ttcatccatt
    43861 attgtgagta tccagtcctt cagcaaaatc caaaggcctt ggaagctgtc tgggattatg
    43921 cttatgaccg tgtaggctat ctaggcacca atactccgat tgaccgttgc tacaagtgtg
    43981 actttgaagg ggattttgaa ccaactgaga gagggtttgc ttgtccaaac tgtggcaata
    44041 gcgatcctaa aacagtagac gttgttaaac ggacttgtgg ctatcttggc aatcctcaag
    44101 cgagaccgat ggttaacggg cgtcacaagg aaatcgctgc gcgtgtcaaa catatgaatg
    44161 gttcaacgat taaaatagct gggcatcaag taacaaatta gaaagaaatg aaatgggaaa
    44221 atatcaacta gacgataagg ggcgcgcaca agtgacccgt tatcacgaga aatactctaa
    44281 aggtggagct ggtaagaaag aacgcttgct tagcttcaga gaacaatttt taaacaagaa
    44341 caagaaaaaa taaaagtgag agccagctct cgcttttctc atagtgggag gtagggatgg
    44401 aattacgcag accaagatta gcggataaga aagctgtttt agatatgatg acagagtttg
    44461 aaaagagcca atcagcccat gatggaggat tttgggatac agagaacttt gtgtatgaag
    44521 agtggttgga aagcaatcag gaacaggaaa tggggattaa tctgcctgaa ggatgggttc
    44581 ctgcaattca gttagtggct ttttctgaga aaggtcaagc agttggattt cttaatctcc
    44641 ggttgcgcct cagtaacttt ctactagaag aaggtgggca cattggctac tccatccgtc
    44701 catctgaaag aggcaagggt tatgcaaaag agactctccg tcagggcttg caagttgcta
    44761 aggaaaagaa catcaagaaa gctctggtga cctgtagcgt gaataatcct gctagcagag
    44821 cagtcattct agcaaatggt ggaatatttg aggatgctcg caatggagtc gagcgttatt
    44881 ggatagaggt agcgaatgaa taatccaaaa ccacaagaat ggaaaagcga ggaacttagt
    44941 caaggtcgta tcattgacta caaggccttt aactttgttg atggcgaagg cgtgcgtaac
    45001 tctctctatg tagcaggctg tatgtttcac tgcgagggat gttataatgt tgcgacttgg
    45061 tcttttaatg ctggcattcc ctatacagca gaattagaag agcagatcat ggcagatctt
    45121 gctcagccct atgttcaagg tttgactttg ttgggagggg agccttttct caatactggc
    45181 attctcttgc cacttgttaa gcggattcgg aaagaattgt cagacaagga catctggtcc
    45241 tggaccggct acacttggga agaaatgatg ttggaaactc cagataaact ggaactcttg
    45301 tcactgattg atattcttgt cgatggaaga tatgatcgaa ctaagagaaa tcttatgctc
    45361 cagtttcgag gttcgtctaa ccaacgaatt atcgatgtgc aaaaatcgct caaaagtggg
    45421 caagtagtga tttgggacaa gctcaatgac ggaaaagaaa gctatgaaca ggtgaagaga
    45481 gaatgaagaa aaaagactta gtagaccaac tagtctcaga gatcgagacg gggaaagtca
    45541 ggacactggg aatatacggt catggagctt caggtaaatc aacccttgca caggaattgt
    45601 cccaagcttt agattctact acagtaaatt tgctagaaac agatccctat atcacctccg
    45661 gacgctattt ggtagtaccc aaggacgcgc cgaatcaaaa ggtgacagcc agtctgccag
    45721 tggcgtatga actggagagt ttgcagagag atatccttgc cttgcaggcg ggtatggatg
    45781 tcttgacaat tgaagaacct tggaaggcta gtgaagtctt gtctggagcc aaaccaattt
    45841 tgattgtcga agggatgtct gttggttttc tacccaagga actctttgaa aaaaccatct
    45901 gtttctacac ggatgaggag accgaattaa agcgacgctt tgctagagat acgactgtga
    45961 gaaatcgcga tgcatccttt atattggcta gccatcagat gagacgggag cagtatctgc
    46021 gatactataa agaaactgag tctaaggcgg atatcttagt ggaccaatca gaagataaat
    46081 ttgatgtcaa gaggacttaa cttatgtata gaagaaaatc cctaatttta gaaagaaaaa
    46141 gtaggaaaac agtttcatcc caaaaaaacg aaaaaaccta acaaatccct tgcaatcgca
    46201 ggggatttgt gttattctat tatggtgctg taaattacag ccttagtttt gatgcaagag
    46261 gttgcgacac gctcggttgc attgccacgc aacaccgcgt cggttttctt gtggagctag
    46321 cctattatct taaatagacg aaaaggagaa aaagatggca aacaaaaaaa tccgtatccg
    46381 tttgaaagct tacgaacacc gtacgcttga cacagcggct gcaaaaatcg tagaatcagc
    46441 tactcgtaca ggtgcacaag ttgcgggtcc aatcccactt ccaactgaac gtagcctcta
    46501 cacaatcatt cgtgcgactc acaaatacaa agactctcgc gaacaatttg aaatgcgtac
    46561 acacaaacgt ttgatcgata tcgttaaccc aactcaaaaa acagttgatg ccttgatgaa
    46621 attggatctt ccaagtggtg taaacgtaga aatcaaactt taatctaaaa tataaaagag
    46681 cagaggctgg tgtttcaatc taattgaaca cgggctaaac tcggtgtgaa aaagataaac
    46741 ttcctagtgt ctgctagaca ctgcgtcagt ttcctatttt cacgttgagt ttgacgccct
    46801 ttgtatctta gacttgagca taaaaaacgc tcgttaaaaa ctttttgaat aaaaatatag
    46861 aaaaggaact attttctcat gacaaaagga atcttaggga aaaaagtggg aatgactcaa
    46921 atcttcactg aagctggcga attgatccct gtaacagtta ttgaagcaac tccaaacgtt
    46981 gttcttcaag ttaaaactgt tgaaacagac ggatacaacg ctatccaagt tggtttcgat
    47041 gacaaacgcg aagtattgag caacaaacct gctaaaggac atgtagcgaa agctaacacg
    47101 gctcctaagc gcttcattcg tgaattcaaa aacgttgaag gcttggaagt tggtgctgaa
    47161 attacagttg aaacattcgc agctggagac gttgttgacg taactggtac ttctaaaggt
    47221 aaaggtttcc aaggtgttat caaacgccac ggacaatcac gtggaccaat ggctcacggt
    47281 tctcgttacc accgtcgtcc aggttctatg ggacctgttg cacctaaccg cgtattcaaa
    47341 ggtaaaaacc ttgcaggacg tatgggtggt gaccgcgtaa caattcaaaa tcttgaagtt
    47401 gtacaagttg ttccagaaaa gaacgttatc cttatcaaag gtaacgtacc aggtgctaag
    47461 aaatctctta tcactatcaa atcagcagtt aaagctggta aataataaag aaaggggaaa
    47521 tcagtcacaa tggcaaacgt aacattattt gaccaaactg gtaaagaagc tggccaagtt
    47581 gttcttagcg atgcagtatt tggtatcgaa ccaaatgaat cagttgtgtt tgatgtaatc
    47641 atcagccaac gcgcaagcct tcgtcaagga acacacgctg ttaaaaaccg ctctgcagta
    47701 tcaggtggtg gacgcaaacc atggcgtcaa aaaggaactg gacgtgctcg tcaaggttct
    47761 atccgctcac cacaatggcg tggtggtggt gttgtcttcg gaccaactcc acgttcatac
    47821 ggctacaaac ttccacaaaa agttcgtcgc ctagctctta aatcagttta ctctgaaaaa
    47881 gttgctgaaa acaaattcgt agctgtagac gctctttcat ttacagctcc aaaaactgct
    47941 gaatttgcaa aagttcttgc agcattgagc atcgattcta aagttcttgt tatccttgaa
    48001 gaaggaaatg aattcgcagc tctttcagct cgtaaccttc caaacgtgaa agttgcaact
    48061 gctacaactg caagtgttct tgacatcgca aatagcgaca aacttcttgt cacacaagca
    48121 gctatctcta aaatcgagga ggttcttgca taatgaattt gtatgatgtt atcaaaaaac
    48181 ctgtcatcac tgaaagctca atggctcaac ttgaagcagg aaaatatgta tttgaagttg
    48241 acactcgtgc acacaaactt ttgatcaagc aagctgttga agctgctttc gaaggtgtta
    48301 aagttgccaa tgttaacaca atcaacgtaa aaccaaaagc taaacgtgtt ggacgttaca
    48361 ctggttttac taacaaaact aaaaaagcta tcatcacact tacagctgat tctaaagcaa
    48421 tcgagttgtt tgctgctgaa gctgaataat ctaaggagga aatatcgtgg gaattcgtgt
    48481 ttataaacca acaacaaacg gtcgccgtaa tatgacttct ttggatttcg ctgaaatcac
    48541 aacaagcact cctgaaaaat cattgcttgt tgcattgaag agcaaggctg gtcgtaacaa
    48601 caacggtcgt atcacagttc gtcaccaagg tggtggacac aaacgtttct accgtttggt
    48661 tgacttcaaa cgtaataaag acaacgttga agcagttgtt aaaacaatcg agtacgatcc
    48721 aaaccgttct gcaaacatcg ctcttgtaca ctacactgac ggtgtgaaag catacatcat
    48781 cgctccaaaa ggtcttgaag taggtcaacg tatcgtttca ggtccagaag cagatatcaa
    48841 agtcggaaac gctcttccac ttgctaacat cccagttggt actttgattc acaacatcga
    48901 gttgaaacca ggtcgtggtg gtgaattggt acgtgctgct ggtgcatctg ctcaagtatt
    48961 gggttctgaa ggtaaatacg ttcttgttcg tcttcaatca ggtgaagttc gtatgattct
    49021 tggaacttgc cgtgctacag ttggtgttgt cggaaacgaa caacatggac ttgtaaacct
    49081 tggtaaagca ggacgtagcc gttggaaagg tatccgccca acagttcgtg gttctgtaat
    49141 gaaccctaac gatcacccac acggtggtgg tgaaggtaaa gcaccagttg gtcgtaaagc
    49201 accatctact ccatggggca aacctgctct tggtcttaaa actcgtaaca agaaagcgaa
    49261 atctgacaaa cttatcgttc gtcgtcgcaa cgagaaataa tattaaacta gtcgcttaag
    49321 caactagtaa atccgccagc tcggtagcgc tccataggag tgcaagccgc tgtggtacaa
    49381 catttaaagg agaaaatata aaaatgggac gcagtcttaa aaaaggacct ttcgtcgatg
    49441 agcatttgat gaaaaaagtt gaagctcaag ctaacgacga aaagaaaaaa gttattaaaa
    49501 cttggtcacg tcgttcaacg atcttcccaa gtttcattgg ttacactatt gcagtttatg
    49561 acggacgtaa acacgtacct gtttacatcc aagaagacat ggtaggccac aaacttggtg
    49621 aatttgcacc aactcgtact tacaaaggtc acgctgcaga cgacaagaaa acacgtagaa
    49681 aataaggaga acataaatgg cagaaattac ttcagctaaa gcaatggctc gtacagtacg
    49741 tgtttcacct cgtaaatcac gtcttgttct tgataacatc cgtggtaaaa gcgtagccga
    49801 tgcaatcgca atcttgacat tcactccaaa caaagctgct gaaatcatct tgaaagtttt
    49861 gaactcagct gtagctaacg ctgaaaacaa ctttggtttg gataaagcta acttggtagt
    49921 atctgaagca ttcgcaaacg aaggaccaac tatgaaacgt ttccgtccac gtgcgaaagg
    49981 ttcagcttca ccaatcaaca aacgtacagc tcacatcact gtagctgttg cagaaaaata
    50041 aggaggtaaa atcgtgggtc aaaaagtaca tccaattggt atgcgtgtcg gcatcatccg
    50101 tgattgggat gccaaatggt atgctgaaaa agaatacgcg gattaccttc atgaagatct
    50161 tgcaatccgt aaattcgttc aaaaagaact tgctgacgca gcagtttcaa ctattgaaat
    50221 cgaacgcgca gtaaacaaag ttaacgtttc acttcacact gctaaaccag gtatggttat
    50281 cggtaaaggt ggtgctaacg ttgatgcact ccgtgcaaaa cttaacaaat tgactggaaa
    50341 acaagtacac atcaacatca tcgaaatcaa acaacctgat ttggatgctc accttgtagg
    50401 tgaaggaatt gctcgtcaat tggagcaacg tgttgctttc cgtcgtgcac aaaaacaagc
    50461 aatccaacgt gcaatgcgtg ctggagctaa aggaatcaaa actcaagtat caggtcgttt
    50521 gaacggtgca gatatcgccc gtgctgaagg atactctgaa ggaactgttc cgcttcacac
    50581 acttcgtgca gatatcgatt acgcttggga agaagcagat actacatacg gtaaacttgg
    50641 tgttaaagta tggatctacc gtggtgaagt tcttccagct cgtaaaaaca ctaaaggagg
    50701 taaataacca atgttagtac ctaaacgtgt taaacaccgt cgtgaattcc gtggaaaaat
    50761 gcgcggtgaa gcaaaaggtg gaaaagaagt agcattcggt gaatacggtc ttcaagctac
    50821 aactagccac tggatcacta accgccaaat cgaagctgct cgtatcgcca tgactcgtta
    50881 catgaaacgt ggtggtaaag tttggattaa aatcttccca cacaaatcat acactgctaa
    50941 agctatcggt gtgcgtatgg gatctggtaa aggggcacct gaaggttggg tagcaccagt
    51001 taaacgtggt aaagtgatgt tcgaaatcgc tggtgtatct gaagagattg cacgtgaagc
    51061 gcttcgactt gctagccaca aattgccagt taaatgtaaa ttcgtaaaac gtgaagcaga
    51121 ataaggagaa ggcatgaaac ttaatgaagt aaaagaattt gttaaagaac ttcgtggtct
    51181 ttctcaagaa gaactcgcga agcgcgaaaa cgaattgaaa aaagaattgt ttgaacttcg
    51241 tttccaagct gctactggtc aattggaaca aacagctcgc ttgaaagaag ttaaaaaaca
    51301 aatcgctcgt atcaaaacag ttcaatctga agcgaaataa tagactaggg aaggagaaat
    51361 ttcaatggaa cgcaataatc gtaaagttct tgttggacgt gttgtatctg acaaaatgga
    51421 caagacaatc acagttgtag ttgaaacaaa acgtaaccac ccagtctatg gtaaacgtat
    51481 taactactct aaaaaataca aagctcatga tgaaaacaat gttgccaaag aaggtgatat
    51541 cgtacgtatc atggaaactc gcccgctttc agctacaaaa cgtttccgtc ttgtagaagt
    51601 tgttgaagaa gcggtcatca tctaatcaaa cctgaaagga gaaaactgaa atgattcaaa
    51661 cagaaactcg tttgaaagtc gcagacaaca gcggtgctcg cgaaatcttg actatcaaag
    51721 ttcttggtgg ttcaggacgt aaatttgcaa acatcggtga tgttatcgtg gcatctgtaa
    51781 aacaagctac tcctggtggt gcggttaaaa aaggtgacgt tgttaaagca gttatcgttc
    51841 gtactaaatc aggtgctcgt cgtgctgatg gttcatacat caaatttgac gaaaacgcag
    51901 cagttatcat ccgtgaagac aaaactcctc gcggaacacg tatctttggc ccagttgcac
    51961 gtgaattgcg tgaaggtggt ttcatgaaga tcgtgtcact tgctccagaa gtactttaat
    52021 ttttaggaac aaactagtcc cctagcttca agctagggtg cccttatggg cgtaagaaaa
    52081 atcaaggaga aacctaatgt ttgtaaaaaa aggcgacaaa gttcgcgtaa tcgctggtaa
    52141 agataaggga acagaagctg ttgtccttac tgcccttcca aaagtaaaca aagttatcgt
    52201 tgaaggtgtt aacattgtta agaaacacca acgtccaact aacgagcttc ctcaaggtgg
    52261 tatcatcgag aaagaagcag ctatccacgt atcaaatgtt caagttttgg acaaaaatgg
    52321 tgtagctggt cgtgttggtt acaaatttgt agacggtaaa aaagttcgct acaacaaaaa
    52381 atcaggcgaa gtgcttgatt aatcacgaag gaaaggagaa gtataatggc aaatcgttta
    52441 aaagaaaaat atcttaatga agtagttcct gctttgacag aacaattcaa ctactcatca
    52501 gtgatggctg tgcctaaagt agataagatt gttttgaaca tgggtgttgg tgaagctgta
    52561 tcaaacgcta aaagccttga aaaagctgct gaagaattgg cacttatctc aggtcaaaaa
    52621 ccacttatca ctaaagctaa aaaatcaatc gccggcttcc gtcttcgtga aggtgttgcg
    52681 atcggtgcaa aagttaccct tcgtggtgaa cgtatgtacg aattcttgga taaattggta
    52741 tcagtttcac ttccacgtgt acgtgacttc cacggtgtcc caacaaaatc atttgatgga
    52801 cgcgggaact acacacttgg tgtgaaagaa caattaatct tcccagaaat caacttcgat
    52861 gacgttgaca aaactcgtgg tcttgacatc gttatcgtaa caactgctaa cactgacgaa
    52921 gagtcacgtg cattgcttac aggccttgga atgccttttg caaaataata taggaggtaa
    52981 atctaatggc taaaaaatca atggtagcta gagaggctaa acgccaaaaa attgttgacc
    53041 gttatgctga aaaacgtgct gcattaaagg cggcagggga ctacgaaggt ttatctaaat
    53101 tacctcgcaa cgcctcaccg actcgtttac ataatcgttg tagagttacg gggcgcccac
    53161 attcagttta ccgcaaattt ggtctgagtc gtatcgcttt tcgcgaactt gcgcataaag
    53221 gtcaaattcc tggtgtaaca aaagcatctt ggtaatttaa gatatcaagg gtgtcaaaac
    53281 tccaagtaaa aataggaaac ttgacgaaga aactaaagtt tctaggaaag tttatctttt
    53341 tcacacagag tttagcccgg gttcaattgg gcttgccaat ttgaacccga gctacagctt
    53401 tggcaaaaaa gaccaatttg ctttggagca ttgcttctgc attaaattgt ctatttttgc
    53461 tcgtgctgtt acgctctttg tatcatgtat taactagcaa gtgcaacttg caaactacta
    53521 gtaagaggag aaaaacaaaa tggttatgac tgacccaatc gcagacttcc taactcgtat
    53581 tcgtaatgct aaccaagcta aacacgaagt acttgaagta cctgcatcaa acatcaaaaa
    53641 agggattgct gaaatcctta aacgcgaagg ttttgtaaaa aacgttgaaa tcattgaaga
    53701 tgacaaacaa ggcgtcatcc gtgtatttct taaatacgga tcaaatggtg agaaagttat
    53761 cactaacttg aaacgtgttt ctaaaccagg acttcgtgtc tacaaaaaac gtgaagacct
    53821 tccaaaagtt cttaacggac ttggaattgc catcctttca acttctgaag gtttgcttac
    53881 tgataaagaa gcacgccaaa agaatgttgg tggtgaggtt atcgcttacg tttggtaaaa
    53941 tcaagataca aagctcgtaa agaacaaagc aaaattagga agttggagaa gtttgtttac
    54001 aaacaagcca acttatctat tttgcacagt tcttagagcg tgttcagttc agctcttgaa
    54061 ctaaataagt atctgaaccc cgtgaaaact ggccgttctg gcctgacaat ttaacaggag
    54121 aaaataaaca tgtcacgtat tggtaataaa gttatcgtgt tgcctgctgg tgttgaactc
    54181 gctaacaatg acaacgttgt aactgtaaaa ggacctaaag gagaacttac tcgtgagttc
    54241 tcaaaagata ttgaaatccg tgtggaaggt actgaaataa ctcttcaccg tccaaacgat
    54301 tcaaaagaaa tgaaaactat ccacggaact actcgtgccc ttttgaacaa catggttgtt
    54361 ggtgtatcag aaggattcaa gaaagaactt gaaatgcgtg gggttggtta ccgtgcacag
    54421 cttcaaggat ctaaacttgt tttggctgtt ggtaaatctc atccagacga agttgaagct
    54481 ccagaaggaa ttacttttga acttccaaat ccaacaacaa tcgttgttag cggaatttca
    54541 aaagaagtag ttggtcaaac agctgcttac gtacgtagcc ttcgttcacc agaaccatat
    54601 aaaggtaaag gtatccgtta cgttggtgaa ttcgttcgcc gtaaagaagg taaaacaggt
    54661 aaataatgtt gagtggttga tcatcaacca ccaacctatt ttccaacttt gtgcatagca
    54721 cacgatttaa aactaaagag gtgaaaactg tgatttcaaa accagataaa aacaaactcc
    54781 gccaaaaacg ccaccgtcgc gttcgcggaa aactctctgg aactgctgat cgcccacgtt
    54841 tgaacgtatt ccgttctaat acaggcatct acgctcaagt gattgatgac gtagcgggtg
    54901 taacgctcgc aagtgcttca actcttgata aagaagtttc aaaaggaact aaaactgaac
    54961 aagccgttgc tgtcggtaaa ctcgttgcag aacgtgcaaa cgctaaaggt atttcagaag
    55021 tggtgttcga ccgcggtgga tatctatatc acggacgtgt gaaagctttg gctgatgcag
    55081 ctcgtgaaaa cggattgaaa ttctaatagg aggacactag aaaatggcat ttaaagacaa
    55141 tgcagttgaa ttagaagaac gcgtagttgc tgtcaaccgt gttacaaaag ttgttaaagg
    55201 tggacgtcgt cttcgtttcg cagctcttgt tgttgttggt gaccacaatg gtcgcgtagg
    55261 atttggtact ggtaaagctc aagaagttcc agaagcaatc cgtaaagcag tagatgatgc
    55321 taagaaaaac ttgatcgaag ttcctatggt tggaacaaca atcccacacg aagttctttc
    55381 agaattcggt ggagctaaag tattgttgaa acctgctgta gaaggttctg gagttgccgc
    55441 tggtggtgca gttcgtgccg ttgtggaatt ggcaggtgtg gcagatatta catctaaatc
    55501 acttggttct aacactccaa tcaacattgt tcgtgcaact gttgaaggtt tgaaacaatt
    55561 gaaacgcgct gaagaaattg ctgcccttcg tggtatttca gtttctgatt tggcataaga
    55621 aaggggataa aatggctcaa attaaaatta ctttgactaa gtctccaatc ggacgcattc
    55681 catcacaacg taaaactgtt gtagcacttg gacttggcaa attgaacagc tctgttatta
    55741 aagaagataa cgctgctatc cgtggtatga ttacagcagt atctcactta gtaacagttg
    55801 aagaagtaaa ctaatgaagt tttaggggat gtgcactgta ccatccccta aaactagata
    55861 tagtcatcta tgatgacatc gtataggcga gttgatgggg gagacaacct tttctccctt
    55921 atcggcgcta gcattttaca aaagaggaga aaataaaaat gaaacttcat gaattgaaac
    55981 ctgcagaagg ttctcgtaaa gtacgtaacc gcgttggtcg tggtacttca tcaggtaacg
    56041 gtaaaacatc tggtcgtggt caaaaaggtc aaaaagctcg tagcggtggc ggagttcgcc
    56101 ttggttttga aggtggacaa actccattgt tccgtcgtct tccaaaacgt ggattcacta
    56161 acatcaacgc taaagaatac gcaattgtga accttgacca attgaacgtc tttgaagatg
    56221 gtgctgaagt aactccagtt gttcttatcg aagcaggaat tgttaaagct gaaaagtcag
    56281 gtattaaaat tcttggtaac ggtgagttga ctaagaaatt gactgtgaaa gcagctaaat
    56341 tctctaaatc agctgaagaa gctatcactg ctaaaggtgg ttcagtagaa gtcatctaag
    56401 agaggtgacc tatgtttttt aaattattaa gagaagctct taaagtcaag caggttcgat
    56461 caaaaatttt atttacaatt tttatcgttt tggtctttcg tatcggaact agcattacag
    56521 ttcctggtgt gaatgccaat agcttgaatg ctttaagtgg attatccttc ttaaacatgt
    56581 tgagcttggt gtcggggaat gccctaaaaa acttttcgat ttttgcccta ggagttagtc
    56641 cctatatcac cgcttctatt gttgtccaac tcttgcaaat ggatatttta cccaagtttg
    56701 tagagtgggg taaacaaggg gaagtaggtc gaagaaaatt gaatcaagct actcgttata
    56761 ttgctctagt tctcgctttt gtgcaatcta tcgggattac agctggtttt aataccttgg
    56821 ctggagctca attgattaaa actgctttaa ctccacaagt ttttctgacg attggtatca
    56881 tcttaacagc tggtagtatg attgtcactt ggttgggtga gcaaattaca gataagggat
    56941 acggaaacgg tgtttccatg attatctttg ccgggattgt ttcctcaatt ccagagatga
    57001 ttcagggcat ctatgtggac tactttgtga acgtcccaag tagccgtatc acttcatcta
    57061 tcattttcgt aatcattttg attattactg tattgttgat tatttacttt acaacttatg
    57121 ttcaacaagc agaatacaaa attccaatcc aatatactaa ggttgcacaa ggtgctccat
    57181 ctagctctta ccttccgtta aaggtaaacc ctgctggagt tatccctgtt atctttgcca
    57241 gttcgattac tgcagcgcct gcggctattc ttcagttttt gagtgccaca ggtcatgatt
    57301 gggcttgggt aagggtagca caagagatgt tggcaactac ttctccaact ggtattgcca
    57361 tgtatgcttt gttgattatt ctctttacat tcttctatac gtttgtacag attaatcctg
    57421 aaaaagcagc agagagccta caaaagagtg gtgcctatat ccatggagtt cgtcctggta
    57481 aaggtacaga agaatatatg tctaaacttc ttcgtcgtct tgcaactgtt ggttccctct
    57541 tccttggtgt gatttccatt ttaccgattg cagctaaaga tgtatttggt ctttctgatg
    57601 ttgttgcctt tggtggaaca agtctcttga tcattatctc tacaggtatc gaaggaatca
    57661 agcaattgga aggttaccta ttgaaacgta agtatgttgg tttcatggac agaacagaat
    57721 aaaagtattt actgaatcag taaatactga gggagtggag gtttaaactc tgacatttgt
    57781 aagagttgga tctcccctct tctattttgt ttttaaatag gggtgaaaag actttttgct
    57841 tctatttaaa aataaaataa ggagatcaaa tcatgaatct tttgattatg ggcttacctg
    57901 gtgcaggtaa gggaactcaa gcagcaaaaa tcgtagaaca attccatgtt gcacatatct
    57961 caacaggtga tatgttccgc gctgcaatgg caaatcaaac tgaaatgggt gttcttgcta
    58021 agtcatatat tgacaagggt gaattggttc ctgacgaagt tacaaatgga atcgtaaaag
    58081 aacgcctttc acaagatgat attaaagaaa caggattctt attggatggt tacccacgta
    58141 caattgaaca agctcatgcc ttggacaaaa cattggctga acttggcatt gaactagaag
    58201 gtgttatcaa tattgaagtg aaccctgaca gcctcttgga acgtttgagt ggccgtatca
    58261 tccaccgcgt aactggagaa actttccaca aggtctttaa cccaccagtt gactataaag
    58321 aagaagatta ctaccaacgt gaagatgata agcctgagac agtaaaacgt cgtttggatg
    58381 ttaatattgc tcaaggagaa ccaatcattg ctcactaccg tgccaaaggt ttggttcatg
    58441 acatcgaagg taatcaagat atcaatgatg tcttctcaga tattgaaaaa gtattgacaa
    58501 atttgaaata aagcgttttt cacacttgca aaaatccgct acaaatgtta tactgagata
    58561 gtctgactta taattgttgt ctctgtgtct agaggcatcg aatcgaaatt tatggaggtg
    58621 cttttgcgtg gcaaaagacg atgtgattga agttgaaggc aaagtagttg atacaatgcc
    58681 gaatgcaatg tttacggttg aacttgaaaa tggacatcag attttagcaa cagtttctgg
    58741 taaaattcgt aaaaactata ttcgtatttt agcgggagat cgtgttactg tcgaaatgag
    58801 tccatatgac ttgacacgtg gacgtatcac ttaccgcttt aaataatcga aaaacttgga
    58861 gggataagaa atgaaagtaa gaccatcggt caaaccaatt tgcgaatact gtaaagttat
    58921 tcgtcgtaat ggtcgtgtta tggtaatttg cccagcaaat ccaaaacaca aacaacgtca
    58981 aggataagat agaaaggaga aaacatggct cgtattgctg gagttgatat tccaaatgac
    59041 aaacgcgtag taatctcatt gacttatgtt tatggtatcg gacttgcaac atctaagaaa
    59101 attttggctg ctgctggaat ctcagaagat gttcgtgtac gtgatcttac atcagatcaa
    59161 gaagatgcta tccgtcgtga agtggatgca atcaaagttg aaggtgacct tcgtcgtgaa
    59221 gtaaacttga acatcaaacg tttgatggaa atcggttcat accgtggtat ccgtcaccgt
    59281 cgtggacttc ctgtccgtgg acaaaacact aaaaacaacg ctcgcactcg taaaggtaaa
    59341 gctgttgcga ttgctggtaa gaaaaaataa tataggaggt aaaagtcttg gctaaaccaa
    59401 cacgtaaacg tcgtgtgaaa aagaatatcg aatctggtat tgctcatatt cacgctacat
    59461 ttaataacac tattgttatg attactgatg tgcatggtaa tgcaattgct tggtcatcag
    59521 ctggtgctct tggtttcaaa ggttctcgta aatctacacc attcgctgct caaatggctt
    59581 ctgaagctgc tgctaaatct gcacaagaac acggtcttaa atcagttgaa gttactgtaa
    59641 aaggtccagg ttctggtcgt gagtcagcta ttcgtgcgct tgctgccgct ggtcttgaag
    59701 taacagcaat tcgtgatgtg actccagtgc cacacaatgg tgctcgtcct ccaaaacgtc
    59761 gccgtgtata atcatcgcat tacactgctt ttcgtttaag agggagtaac taaatgatcg
    59821 agtttgaaaa accaaatata acaaaaattg atgaaaataa agattatggc aagtttgtaa
    59881 tcgaaccact tgaacgtggc tacggtacaa ctcttggtaa ctctcttcgt cgtgtacttc
    59941 tagcttctct accaggagca gctgtgacat ctatcaacat tgatggtgtg ttacatgagt
    60001 ttgacacagt tccaggtgtt cgtgaagacg tgatgcaaat cattctgaac attaaaggaa
    60061 ttgcagtgaa atcgtacgtt gaagacgaaa aaatcatcga actggatgtt gaaggtcctg
    60121 ctgaagtaac agctggtgac attttgacag atagcgatat tgaaattgta aatccagatc
    60181 attatctctt tacaatcggt gaaggttctt ctctaaaagc gactatgact gttaacagtg
    60241 gtcgtggata tgtacctgct gatgaaaata aaaaggataa tgcaccagtt ggaacacttg
    60301 ctgtagattc tatttataca ccagttacaa aagtcaacta tcaagtggaa cctgctcgtg
    60361 taggtagcaa tgatggtttc gacaaattaa cccttgaaat cttgacaaat ggaacaatta
    60421 ttccagaaga tgctttaggg ctttcagcac gtattttgac agaacatctt gatttgttta
    60481 caaatcttac tgagattgct aagtcaactg aagtgatgaa agaagctgat actgaatctg
    60541 acgaccgtat tttagatcgt acgattgagg aactggactt gtctgtgcgt tcatacaact
    60601 gtttaaaacg tgccggtatc gatactgtgc atgatttgac agaaaaatct gaagcagaga
    60661 tgatgaaagt acgaaatctt ggacgcaaga gtttggaaga agtgaaactc aaactcattg
    60721 atttgggtct tggattaaaa gataaataaa ggaggaatac atggcttacc gtaaactagg
    60781 acgcactagc tcacaacgta aagcaatgct tcgcgatttg acaactgacc ttttgatcaa
    60841 cgaatcaatc gtgacaactg aagctcgtgc taaagaaatc cgtaaaactg ttgaaaaaat
    60901 gattactcta ggtaaacgtg gtgatttgca tgcacgtcgt caagcagctg ctttcgtacg
    60961 taatgaaatc gcatctgaaa actatgatga agcaactgat aagtacactt ctactacagc
    61021 acttcaaaaa ttgttctcag aaatcgcacc tcgttatgct gaacgtaacg gtggatacac
    61081 tcgtatcctt aaaactgaac cacgtcgtgg tgatgcagcg ccaatggcga tcatcgaatt
    61141 agtataaaat catcaatttt gttgagtgtt atgatgatgg agtcttgtgc tcttagtcta
    61201 gctctggtct accgctagga tttcggtcct agcgggaaca ctcatcataa gttgggatag
    61261 tagacgcttg tttacgaaat tgtttttttc ttaagaacaa cttcgtaagc aggcgttttt
    61321 gagtattttc gttagaatta tgctatacta tttgaaaaga atcctgttta atgttaaggt
    61381 ttcttatttt aagaagaatt ggagtttact tatgaaagcg attataactg ttgttggtaa
    61441 agataaatct ggaattgttg caggtgtttc tggtaaaatt gcagaattag gattgaatat
    61501 tgacgatatc tctcaaactg tattggatga atattttacg atgatggctg ttgtatctag
    61561 tgatgaaaag caagatttta cctatcttcg taatgaattt gaagcttttg ggcaaacttt
    61621 gaatgtaaaa atcaatattc agagtgcagc gattttcgaa gctatgtata atatctagga
    61681 ggtcatcatg gatattagac aagttactga aaccatcgcc atgattgagg agcaaaactt
    61741 cgatattaga accattacca tggggatttc tcttttggac tgtatcgatc caaatatcaa
    61801 tcgtgctgcg gagaaaatct atcaaaaaat tacgacaaag gcggctaatt tagtagctgt
    61861 tggtgatgaa attgcggctg agttgggaat tcctatcgtt aataagcgtg tatcggtgac
    61921 acctatttct ctgattgggg cagcgacaga tgcgacggac tacgtggttc tggcaaaagc
    61981 gcttgataag gctgcgaaag agattggtgt ggactttatt ggtggttttt ctgccttagt
    62041 acaaaaaggt tatcaaaagg gagatgagat tctcatcaat tccattcctc gcgctttggc
    62101 tgagacggat aaggtctgct cgtcagtcaa tatcggctca accaagtctg gtattaatat
    62161 gacggctgtg gcagatatgg gacgaattat caaggaaaca gcaaatcttt cagatatggg
    62221 agtggccaag ttggttgtat tcgctaatgc tgttgaggac aatccattta tggcgggtgc
    62281 ctttcatggt gttggggaag cagatgttat catcaatgtc ggagtttctg gtcctggtgt
    62341 tgtgaaacgt gctttggaaa aagttcgtgg acagagcttt gatgtagtag ccgaaacagt
    62401 taagaaaact gcctttaaaa tcactcgtat cggtcaattg gttggtcaaa tggccagtga
    62461 gagactgggt gtggagtttg gtattgtgga cttgagtttg gcaccaaccc ctgcggttgg
    62521 agactctgtg gcacgtgtcc ttgaggaaat ggggctagaa acagttggca cgcatggaac
    62581 gacggctgcc ttggccctct tgaacgacca agttaaaaag ggtggagtga tggcctgcaa
    62641 ccaagtcggt ggtttatctg gtgcctttat ccctgtttct gaggatgaag gaatgattgc
    62701 tgcagtgcaa aatggctctc ttaatttaga aaaactagaa gctatgacgg ctatctgttc
    62761 tgttggattg gatatgattg ccatcccaga agatacgcct gctgaaacca ttgcggctat
    62821 gattgcggat gaagcagcaa tcggtgttat caacatgaaa acaacagctg ttcgtatcat
    62881 tcccaaagga agagaaggcg atatgattga gtttggtggt ctattaggaa ctgcacccgt
    62941 tatgaaggtt aatggggctt catctgtcga cttcatctct cgcggtggac aaatcccagc
    63001 accaattcat agttttaaaa attaagaaaa taggagaaat tttaagttct atttaagatt
    63061 agatgtgtat actataatca ttaaataaag acctcctaat attatttgaa acagataaca
    63121 ctgaattagt ttgaatttga ttttcatcta atatctttat ttaatgaact cctaaacttt
    63181 ttcataataa tctccttcaa aagtcgcctg tatgggtggc ttttatttta tcattcatga
    63241 tataatagaa gcaaacggag gacggaaaat ggtaaaagta cgattgtatt tggtacgtca
    63301 tggcaagacc atgtttaaca cgattggtcg cgcgcaaggt tggagcgata ctcccttaac
    63361 tgctgaaggt gaacgaggga ttcaagagtt aggaattggt ttgcgagaat ctgatctaca
    63421 gtttgagcgc gcttattcga gtgattctgg tcgtaccatt cagaccatgg gaattatcct
    63481 tgaagagctt ggcttgcagg ggaaaatccc ttatcgcatg gacaagcgta tcagagaatg
    63541 gtgtttcggt agttttgatg gagcctatga tggcgatctt ttcatgggca ttattcctcg
    63601 tatctttaat gtggaccacg ttcaccaatt gtcttatgct gaactggctg agggcttggt
    63661 agaggtcgat acagctggtt gggctgaagg ctgggaaaaa ctcagtggcc gaattaagga
    63721 aggctttgaa atgattgcaa aagaaatgga agatcaaggt ggaggtaacg cccttgttgt
    63781 cagccatgga atgactattg gaaccattgt ttatctgatt aatggcatgc atccgcatgg
    63841 tctagataat ggtagcgtga cgattcttga atatgaggac ggtcagttta gggttgaagt
    63901 tgtcggtgac cgtagttacc gagagctagg acgtgagaag atggaagaag gctctattta
    63961 atcagtctag acttgcttgc catgagctag ggatttgata agaatatcaa gataagaaaa
    64021 aacagccgag ggtactcctt tcggctgttt ttgatgtgga aaactaaagt gtaatgctat
    64081 tgcttttaga gattttcata aacaagagca aggaacctac tgttagaaca gtcaggatag
    64141 ttgacaaggc tgcggctaca ccgtaatttc ctctgagaac ctctgtataa atagctacag
    64201 tcattgttct tgttttgaca ttgtagagga ggatagagga tagaagtaga gagttctgaa
    64261 atcagtgtga cccaagatag gatggctcca gaaataatac ccgatagcat cattggagtt
    64321 gtaatcttag caaaggtatt gagacgacta cttcctaagc tttcagcagc ttcttcaata
    64381 cttggtgcta tttgttgtaa gctagcaaca gatgagcgaa tagtataagg taatcttctg
    64441 acagatagag acataatcaa gatgaaagca gtccctgtaa tcataagaaa tccacttcca
    64501 aatagaccag tattgaagga agaaatgaag gcaatcccta gaacggttcc tgatacaata
    64561 taaggtacca tactgaggct gtcaattaag tttgtaaaca aattccgttt tctaacggct
    64621 aggtaggaga taaatgtcgc aaatagaaca actagaacta aggcaatcaa agggatacga
    64681 atggtattga aaatagcaga tcccatacga ttgaaagcta ccttgtaact gtttggagaa
    64741 taacctttaa caaataccat acctgatgtt tttaggaaag aggtataaat taagtagatt
    64801 tgaggtaaaa cagagataaa gataattccg tagactgttg cataaatggc agccattttt
    64861 ccttttgtag tttttttagg ctcaattgga tggagcggat tcatgctgaa actgtagcgg
    64921 tttgcaatgt gtttttggat aaggaaaatt gccaaggcaa tgataatcgc cataattgca
    64981 aaagcagaat ttcctccaac ctcgctaata aattgggtat aaatcaggac agggaaagtc
    65041 cgatatcctt cgccaatcaa cataggcgtt ccaaagtctg agaatgctct cataaataca
    65101 agcaaggagc tgctagtaag gttggaacta gaagaggtaa aacaaccgtt acgataggtt
    65161 taaatccgaa ggaccccatg ctttcagctg cttcaagtag agaattgtca atactgttca
    65221 ttgttccagc aacatataga aataccagtg ggaatagttg cagtgtaaag acaagtacaa
    65281 ttcctttgaa tccataaata tcgatagctg gaagatgaag ggcatttgtc aaaaatttag
    65341 tgatgccccc atttcgtccc agcaagagaa cccaggagta ggctcctacg aaaggagctg
    65401 acatggaagc aatgataatc aatatttgta gaaatttctt ccccttgaag tcatacatag
    65461 agaagagata agctaatagg gttcctacaa ctaaggaagt gacagtagcg gtaatggaaa
    65521 ccctgaaact gttgactagt gtctcagagt agtaggcttt actaaagaaa gtgacaaaat
    65581 tagatagtga gaattgtcct tcatgtataa gtgcttgctt gagcacggta acgataggat
    65641 aaacgagaaa gacaagatag gtaagaaaga tgaagaaaga ggaggctgtc caaatattta
    65701 gttttttaca ttccatggtt gactcctttt atcaggtttt gggaaccatc tacagaaaag
    65761 atgtttaatt tttgcgtatt gattcgtaga cgaatacgat tgcctttttg tagttcttct
    65821 tcaaaagttg attcttcact aacttaaatt tttgaggcaa aacctgtctc aatgaaatac
    65881 tccgtattta gtccaagata gacgctatcg ctaatagttc cttcgatatc tccagattca
    65941 tctttgataa actcttcggg acgaatgctt acatgaatag cttgctcctc aacctgatca
    66001 agagctggca ttcgaagggc atagccatct gaaaagacga tataagcgcc gtcgctccgt
    66061 ttttcaagat tggcagggat aatatttgtg cgtccgataa aggttgccac aaactcatta
    66121 gctggtttat gatagagtta ttttggtcgg ccgatttgtt ggatcacccc atctttcata
    66181 acagcaattt ggtctgaaat agccatggct tcttcttggt cgtgggttac ataaacagtt
    66241 gtaattccca cttcgtgttg gatttctcgg atggcttgac gcatatccaa gcgaagtttg
    66301 gcctccagat tactaagtgg ctcgttcatg aggagaacac ttggattaac cgctaaggcg
    66361 catgccaagg tgacacgttg ttgttgtcca ccactgagtt tatcgggctt tcgatccgca
    66421 tattgagcaa tttgcatgag ttcaagatac ttgttggtct gttgaatcaa ttcttctttt
    66481 ggaaccttct tttgcataag accaaaagca acgttgtctc ggacagtcaa atgtgggaaa
    66541 atagcgtagt tttggaaaac catcccgata ttgcgtttgc tgggttccat attattgatt
    66601 tttgtatcat cgaagtaaaa ttctccacct tcgatactgt tgaaacctgc aatcatacga
    66661 agaagggtcg ttttcccaca tcctgaaggt ccaagaaggg taaagagact tccttttgga
    66721 attgtaatgt tcaaattctc aataacaggg acatcgtggt agattttttt ggcgttaata
    66781 attttgatct cactcatagt gaacctcttt tactgtttag attggatatc tgtaaagact
    66841 tcgttgtatt tcttaacgat atctgattta ttcttgatga cataatcata atcttcagtg
    66901 agtgttttga ttttgtcaat tggtttcatg ttttcgcttg ttttagcatt tttacgaaca
    66961 ggacggttag tagtggttgt accaagtgta tcttgtactt cttgagagat aataaaatcg
    67021 ataaatttct tggcattttc catattttta gattttttaa cgatagcagc actagcaggt
    67081 aggaagacgg ttccttcttt tggatagact accttaatgt tagctccgtc atttaagagt
    67141 ttaactgctg gatcttcata agagagacca acagtcattt ctccatcagc gactgcttta
    67201 tagacaccag atgaacttaa accgatttta tagtatattg aaactagaat agtacacatc
    67261 tacttctaaa acattgttag aaatcgattt gactgtcctg attaatttgt cttgttctta
    67321 tttcatttta ctataccatc aataagtgtg aaaagatctt ttacataaga ccaagcctta
    67381 tcatctttgt aaccaccttg agcttgtagc atatttgtta attgagcaaa ggcgctagaa
    67441 gagtttgctg ggtcagcagt tgcgattttt ccttttagtt caggtttgag aaggtcgcta
    67501 tatccttcga tgttcatgcc tttagttaaa tcagggtgga cgattaaaac actaccatct
    67561 agtgtataag gagtagagaa gccagttgtg ttttgatatt ctttgataac attatcattt
    67621 tcttttgaaa tatagttttc aaagagttct ccgtgggtag catattgtgt ataagaacca
    67681 ccaaagataa catcagctac aggaacttct ttttctgact ctagtttttt gaaaagttct
    67741 ccagtaccag cttgaatcag ttctattttg ataccatatt tttcttcaaa ggcaggaata
    67801 gttgctccaa ttaagccttc tgagtttggt gaataaacga ctagcgaacc accgtctcct
    67861 ttatcagatg aactgtcatc ggcagattca ttagaagaac aagcagcata atacatccat
    67921 ttctttttca tgatggatac ctccgttgtg ttatttaagt ttattttaaa acaatataag
    67981 cgtttttaaa acctacaatt ctatcctata gtgtattgaa tctataacag tacactttga
    68041 ctgctaaaat atttctataa attaatttga ctttcctgat agagatgttc acatcttatt
    68101 tcaattcact atattagagt aaaattctct acaaaaagaa gaatagccta tttgactatt
    68161 cttccgagtg atttcaattt ctttggggaa atatggagat actttttaaa tactttggca
    68221 aaatatttat agtctgaaaa tccaacttgg tcagagatag cgcttaaagg ggagttggga
    68281 gattcagcca tcttatctat agcttgtttc aggcgatatt gtaagatata ttcatttaga
    68341 gtcatgggga agtcttcttt gataacctta tatagatgct tgttatctgc aaatagctag
    68401 agcatttcaa ggaaatgaac tagaaataac aattaatatg gtggttcaga aatacctttt
    68461 gataatcaat aagatcttca ggatgaagtg cgttgactcc atccatttca tatttccgat
    68521 ttaataaacg atatttgttt tcaccaaatt gatgaaaagg gagtagttga acttggtcga
    68581 tatttaatga gttaaataga gtagcgaatt tttctgcatc ctctaaacta ttgttaaaat
    68641 taggaataac tgggattctt aaaacgatag ttttattttg agaaaaagca taatgaatgt
    68701 ttttaataat catttgatta aaaaccccag tcactttttt atgttttata gaattataat
    68761 gttttaggtc tgtgtagata aaatccacat attgaattaa atcaataaat ttttcatgat
    68821 caacaaaggc agtagtttca atggcagtgt gtatgtgatg ttctttagct gattttaaga
    68881 tggctttagc aaattcaaac tgagcaaata tttcacctcc tgataaagtt aaacctccac
    68941 cggattcttc gtaaaattct ttgtctttta atacctctgt aataatttct tctacagtct
    69001 tttcttcacc gactaaggtg aatttctctc gttgagcatc tttcattttt tcaggtttca
    69061 ttctttgaga ttcaggatta gaacaccatg gacagcgcag aggacatcct tttaaaaaaa
    69121 cagttgtacg aatacccggg ccgtcatgaa ttgaaaagtg ttgaatatta aaaataattc
    69181 ctttagatat ttccataaga gttcctcctc ttcataagtc tatcctatca caaaaacgaa
    69241 agaaaaacaa ttacgaacga aagtttaatt tgttgttttt tgctttttat tttggtagaa
    69301 taaaacggag gtgtaaaatg aaaagattgg aacaaattat taaattagta tcagaatatg
    69361 aaaagatcga cgttaataca ttatcggaaa aattaaatgt atcgaaagta acgattagaa
    69421 aagatttaga taaattagag tcaaaaggtt tattacacag agagcatgga tatgctgtat
    69481 taaatagtgg agatgactta aatgtacgtt tgtcaattaa ttatgaaatt aagagaaaaa
    69541 ttgttcagga agcagtaaaa ttggtgtcag ataatgaaac aataatgata gaatctggat
    69601 cgacctgtgc tttacttgct gaggaaattt gcaagcaaaa aagaaatgtt acgattgtaa
    69661 caaattcatt ttttatagca aattttgtga gagcttatga ttcatgtcgt attattgttc
    69721 ttggtggaga gtttcagaag gattcacagg ttactgtggg acctttatta aaagaaatga
    69781 tacagacttt tcatgtgcgt caagcttttg ttgggacaga tggctacgat aaagagatgg
    69841 gctttacagg aaaagattta atgcgcagtg aggtagttca atatatttca gcagcgtcgg
    69901 ataaagtcat tgtactaact gactcaagta aatttgataa aaggggtaca gtaagaagat
    69961 ttgctttaag tcaagtctat gaagtaataa cagacgaaaa actttctaaa caaaatatag
    70021 ctacattaga aaatgctggg ataatggtta aggtagtttc gtaagaggtt aagtgtatga
    70081 atcaagatag gaataaactg ctttctaaaa ttgcttatct gtattatatt gaaaacttaa
    70141 atcagtcaca aatagcagca aaattaggaa tttatagaac ctctattagt agaatgttaa
    70201 cagaagcaag gaatgcagga attgttaaaa ttgaaataga gaattttgat acaaatatgt
    70261 ttaagttgga aaattatgta aaagaaaaat atggtctgga aagtttagaa attattccaa
    70321 atgaatttga tgataatcca acaattttat ctgaaagaat ttctcaagtt gcagcaggtg
    70381 tccttaggaa tttaattgat gataatatga aaattggctt ttcttggggg aaaagtttaa
    70441 gtaatttagt agatttaatt cacagtaaaa gtgtccgaaa tgttcacttc tatcctctag
    70501 caggtggtcc tagtcacata cacgctaaat accatgtgaa tacactgatt tatgaaatgt
    70561 ctagaaaatt tcatggagag tgtacattta tgaatgcaac gattgtgcaa gaaaataaat
    70621 tgttagcaga tggtattttg caatcaagat attttgaaaa tttgaaaaat agttggaaag
    70681 atttagatat agctgtagtc ggaattggtg attttagcaa taaaggaaaa catcaatggt
    70741 tagacatgct tacagaggat gactttaaag aattgaccaa agttaaaact gtaggagaaa
    70801 tttgttgtcg attttttgat tcaaaaggta aagaagtcta tgaaaactta caggaaagaa
    70861 cgatagcaat ctctttggaa gatttaaaaa atattcctca aagtttagct gttgcttacg
    70921 gtgatacgaa agtatcttcg attctttctg tcttgcgtgc taatttagta aatcatttga
    70981 ttacagacaa aaatacaatt ttaaaagttt tggaagaaga tggggatttg acttttagag
    71041 agattctagg tgagtgaaaa tgatagactg atcagtttat cgttttttct ttttagtcga
    71101 ttgcacattt gtgctcatat aaacaaaaat agtttatctg ttgtttttgg attgacaact
    71161 ttattatgta gttgtattct atagttacaa aagaaaattt taaaatttca aatgaaaaaa
    71221 gctttttaca tagtgaaatg aggaggaatt tatggaaatt attgttccag atcaaattat
    71281 catgggttta attttatatg ctggtgatgc gaaacaacat atttataaag cgttagatta
    71341 cataaaaaat ggtacatgtg aacggtgtga agaagaaatc cagttagctg atgccgcctt
    71401 attagaagcc cataatctac aaacaaaatt cttggcacaa gaagcgtctg gtacaaagac
    71461 agaaattaca gctctctttg ttcattcaca agatcatctc atgactagta tgacggagat
    71521 taatttaatc aaagaaatta ttagtttgag aaaagaactt cataaaaaat aatactagag
    71581 tattatcatt gttattaaca tagaggagga aaacataatg gtgaagattg gtttgttttg
    71641 tgcagcaggt ttttctactg gtatgcttgt aaataatatg aaaattgcag cgcaagctag
    71701 tggagttgag gcagaaatag aggcgttttc tcagtctaaa ttagcggatt atgcgccaaa
    71761 tatagatgtt gcactattgg gtccacaagt tgcttataca ttagataaat caaaagaaat
    71821 ttgtgataag tgtgatgttc cgatagctgt tattccgatg atggactatg gtatgttaga
    71881 tggaaaaaaa gtattagatt tggccctatc tttgattagt gggtaagaaa aggagattta
    71941 ttatggcaaa gatggatgtt cagaaaatca ttgcaccgat gatgaagttt gtgaatatgc
    72001 gtggcattat agctctaaaa gatgggatgt tagcaatttt gccattgaca gtagttggta
    72061 gtttattctt gattatggga caattgccgt tcgaaggatt aaataagagc attgctagtg
    72121 tttttggagc taattggaca gagccgttta tgcaagtata ttcaggaact tttgctatta
    72181 tgggtctaat ttcttgtttt tcaattgcct attcttatgc taagaatagc ggagtagagg
    72241 ctttaccagc tggagttcta tctgtatctg cattctttat tttgctaaga tcatcttata
    72301 tccctaaaca aggtgaggca attggggatg ctattagtaa agtttggttt ggaggtcaag
    72361 gaattatcgg tgctatcatt ataggtttgg tagtaggaag tatttatacc ttctttataa
    72421 agagaaaaat tgttattaag atgccagaac aagttccaca agctattgcc aaacagtttg
    72481 aagcaatgat tccagcattt gtaattttct tactttctat gattgtatat attttagcga
    72541 agtcattgac taatggcgga acattcatag aaatgattta ttctgctatt caagttccat
    72601 tgcaaggttt aactggatct tggtatggtg caattggaat tgcattcttt atatcatttt
    72661 tgtggtggtt tggtgttcat ggacaatcgg tagtaaatgg agtagtgaca gctctgcttt
    72721 tatctaatct tgatgctaat aaagctatgt tagcctctgg taatctatca ttagaaaatg
    72781 gtgcacatat tgttactcaa caatttttag attcattttt aattctatca ggttcaggga
    72841 ttacgtttgg tcttgtagtt gccatgcttt ttgcagcaaa atcaaaacaa taccaagcct
    72901 taggaaaagt tgccgctttt ccagcaatat ttaacgtaaa tgagccagtt gtatttggat
    72961 ttccgattgt catgaatcca gttatgtttg tacctttcat tcttgttcct gtacttgcag
    73021 ctgtgatagt atatggagct attgcaacag gtttcatgca gccattctca ggggtaacat
    73081 tgccttggag tacaccagct attttatcag gatttttggt gggtggatgg caaggagtta
    73141 ttactcagct ggtgatatta gcgatgtcta cattggttta ttttccattc tttaaagtac
    73201 aggatcgttt agcttaccaa aatgaaatca aacaatctta gaggtatttg tgtgttactg
    73261 ttaaactcac acatttgtgc taaaaattag agagttaaaa tttttctagt taaaagcttg
    73321 aaaatttcta taaaaatcgg tattatattt tcgaaagaaa taaaaatatt ttcgaaagaa
    73381 aggtggttac gatggtaaat acagaagtag caagaacaac aatcaagaca gaatattttg
    73441 gcagccttac tgaaaggatg aacaaatatc gagaagatgt tttaaataaa aaaccttata
    73501 ttgatgctga gagagcagtt ctagcaacac gcgcctatga acgatacaag gaacaaccta
    73561 atgtcctaaa acgtgcatat atgctgaaag aaattttgga aaatatgact atctatattg
    73621 aagaagaatc tatgattggg ggaaatcaag cttcttccaa taaagatgct cctatttttc
    73681 cggaatatac gctagaattt gttctcaatg agttggatct ttttgaaaag cgtgatggag
    73741 atgttttcta tattacagaa gaaacaaaag aacaacttag aagtattgct ccgttttggg
    73801 aaaataataa tttacgtgct agagctggtg ccttattacc tgaagaagtg tctgtttata
    73861 tggaaacagg attcttcggt atggaaggta agatgaattc tggagatgct cacctagcag
    73921 ttaactatca gaaacttttg caatttggct taagaggttt tgaagagcgg gctcgtaaag
    73981 caaaagcagc tctagattta acagatccag caagtattga taaatatcat ttttacgact
    74041 ctatatttat cgtaatcgat gctattaaag tatatgcaaa gcgctttgtt gctcttgcta
    74101 aaagtttagc cgaaaatgca aatcctaaac gtaagaaaga attacttgag attgcagata
    74161 tttgctctag agtcccatat gaaccggcaa ctacttttgc agaagctatt caatcagttt
    74221 ggtttattca atgtatttta caaattgaat ctaatggcca ctctctttca tatggccgtt
    74281 ttgatcaata tatgtatcca tatatgaagg ctgatttaga aagtggtaaa gaaacagaag
    74341 atagcattgt tgaacgtctg acaaatcttt ggattaagac aattacaatt aataaggttc
    74401 gcagtcaatc acatacattt tcttcagcag gaagtccttt atatcaaaat gttacaattg
    74461 gtggacagac tcgagataag aaggatgctg ttaacccatt atcttatttg gtattaaaat
    74521 cagttgcaca aacccatcta ccgcaaccta atctaactgt acgttaccat gcaggtttag
    74581 atgctcgttt catgaatgag tgtattgaag tgatgaaact tggttttggt atgcctgcat
    74641 ttaataatga tgagattatt attccttctt ttattgcaaa aggagtattg gaagatgatg
    74701 cttatgatta cagtgccatt ggatgtgttg aaacggcagt tccagggaaa tggggctatc
    74761 gttgcacagg tatgagttat atgaacttcc ctaaggttct acttatcacg atgaatgatg
    74821 gaattgatcc ggcttcgggt aaacggtttg caccaagctt tggtcatttt aaggatatga
    74881 agaacttttc tgaattagaa aatgcttggg ataaaacact aagatatttg acacgaatga
    74941 gtgttattgt tgaaaattct attgatttat cattggaacg agaagttcct gatattctat
    75001 gttcagcatt gactgatgat tgtattggtc gtggaaaaca ccttaaagaa ggtggagcag
    75061 tatatgatta tatatcagga ttgcaagttg gaattgcaaa tttgtcggat tcattagctg
    75121 caattaaaaa attggtgttt gaggaagaac gtataagccc aagtcagctt tggcatgcac
    75181 tggaaacaga ttatgccgga gaagaaggta aggtcattca agaaatgttg attcatgatg
    75241 cacctaagta tggtaatgat gatgattatg ctgacaaatt ggttactgct gcttatgaca
    75301 tttatgttga tgaaattgct aaatatccta atacacgtta tggaagaggt ccaattggag
    75361 gaattcgtta ttcaggaaca tcttctatct cagccaacgt agggcaggga cgtggaacat
    75421 tagcaactcc agatggacgc aacgcgggta caccgttagc agagggttgt tcaccatcac
    75481 ataatatgga tcaacacggc cctacatctg ttttaaaatc tgtttcaaaa ttaccaacag
    75541 atgaaatcgt aggtggggtt ctcttaaatc agaaagtaaa tcctcaaacg ttagccaaag
    75601 aagaagataa attaaaacta attgctttgt tacgaacatt ctttaatcgt ttacatgggt
    75661 accatattca atacaatgtt gtttccagag agacgctgat tgacgctcag aaacatcctg
    75721 aaaaacacag agacttaatt gttcgtgttg caggatactc tgcattcttc aatgttcttt
    75781 ctaaggcaac ccaagatgac attataggac gtactgagca tactttgtaa aataaagagg
    75841 ttctttttat ggaatttatg cttgacacat taaatttaga tgagattaaa aagtggtctg
    75901 aaattttgcc gctagctggg gtaacttcaa atcccactat tgcaaaaaga gagggttcta
    75961 ttaatttttt tgaacgaatc aaagatgtaa gagaattgat tggctctaca ccctctattc
    76021 atgttcaggt gatttctcaa gattttgaag gcatcttaaa ggatgctcat aaaattcgaa
    76081 gacaagcagg agatgatata tttatcaaag tacctgttac tccagctgga ttacgtgcaa
    76141 taaaggcgct aaaaaaagag ggctaccata tcactgcaac agctatttat acagttattc
    76201 agggattatt agctatcgaa gcaggagcgg attacctagc tccatattat aatagaatgg
    76261 aaaatctgaa cattgattca aattctgtca ttcgtcaatt agctcttgct attgatagac
    76321 agaactctcc tagtaagatt ttagctgcat cctttaaaaa tgtagcacaa gtaaataatg
    76381 ctttagctgc aggtgcgcat gctgttacag caggagcgga tgtttttgaa tcagctttcg
    76441 ccatgccatc tatccaaaag gcggttgatg atttttctga cgattggttt gttattcaaa
    76501 atagtcgttc catttagata gagaggaaat acatatgaga atttttgcta gtccttctag
    76561 atatattcag ggggaaaatg ccttgtttga aaatgccaaa tcaattttgg atttgggaaa
    76621 ttaccctatt ctattatgcg atcagttggt ttatgatatt gttggaaaac gatttgaaga
    76681 ttacctacat aggtatggtt tccatattgt tctggcgcta tttaatggtg aagcttctga
    76741 caatgaaatc aatcgagttg ttgccttggc tgagaaagaa aattgtgata gtattatcgg
    76801 tcttggtggg ggaaagacga ttgatagcgc aaaagctatt gcagatttga ttgaaaagcc
    76861 tgttattatt gctccaacaa ttgcatcgac cgacgcacct gtatctgctt tatctgttat
    76921 ttatacagat gaaggtgcat ttgatcatta tctattttat tctaaaaatc cagatttagt
    76981 tttggttgat acaaaagtta tttcacaagc ccctaagcgt ttattagcgt ctggtattgc
    77041 agatggttta gcaacttggg ttgaggcgcg tgcggttatg caggcaaatg gaaaaactat
    77101 gttgggacaa cagcaaacat tggctggagt tgcaattgcg aagaaatgtg aagaaacgct
    77161 gtttgcagat ggtttacagg ctatggcagc ttgtgaagct aaagtggtga caccagcatt
    77221 agaaaatatt gttgaagcta atactttatt gagtggtcta ggttttgaaa gtggaggatt
    77281 agctgcggcg catgcaattc ataatggttt tactgcattg acaggtgaca ttcatcattt
    77341 aacacatggt gaaaaagtag cttatggaac tttagtacaa ctattattgg aaaatagacc
    77401 taaagaagaa cttgataagt atattgagtt ttacaaaaaa attggtatgc caacaactct
    77461 aaaagaaatg catttggatc aagttggata tgatgattta ataaaagttg gtaaacaagc
    77521 aactatggag ggtgagacaa ttcatcagat gccgtttaag atttcgcctt cagatgttgc
    77581 tcaagctatt atcgctgtag atgcctatgt aaattcaaaa taaacaataa ggactactgt
    77641 tttccaaatg gtagtctttt attgatccct gtattgaatt ctatagcaga ttgaaatagg
    77701 atgagaacaa atcgattggg aaagtaaaat taatttctat aaatgtttta gcaattgttt
    77761 cgtactattt cagattcagt ccactatacg ttcttcataa atcaaaaagc gacataggtt
    77821 gtcggctatt tattgtgaat acattaatta gcattccagt tttatcttcg gtctaaaata
    77881 agtattttgt gctatacgag ataagcttct tgacttactc cttgatttac tgcataacaa
    77941 tgggataaaa agtgggagat agagcaattc atagtcatca aaattaatga gatacagtat
    78001 acagtttttt ctttaaacac atttcaaatt ccctcaaaaa tggtataata gtaacatcac
    78061 aaaattggag agagaccatg agtttttaca atcataaaga aattgaacct aagtggcagg
    78121 gctactgggc agaacatcat acatttaaga caggaacaga tgcatcaaaa cctaagtttt
    78181 atgcgcttga tatgttccct tatccgtctg gagctggtct gcatgtagga cacccagaag
    78241 gttatactgc aaccgatatc ctcagtcgtt acaaacgtgc gcaaggctac aatgtccttc
    78301 acccaatggg ttgggatgct tttggtttac ctgcagagca atacgctatg gatactggta
    78361 atgacccagc agaatttaca tcggaaaaca ttgccaactt caaacgtcaa atcaatgcgc
    78421 ttggattttc ttatgactgg gatcgtgaag tcaacacaac agatccaaac tactacaagt
    78481 ggactcaatg gattttcacc aagctttacg aaaaaggctt ggcctatgaa gctgaagtgc
    78541 cagtaaactg ggttgaggaa ttgggaactg ccattgccaa tgaagaagtg cttcctgacg
    78601 gaacttctga acgtggaggc tatccagttg tccgcaaacc aatgcgccaa tggatgctca
    78661 aaatcacggc ttacgcagag cgcttgctca atgacttaga tgaactagat tggtcagagt
    78721 ctatcaagga tatgcaacgc aactggattg gtaaatcaac tggtgccaat gtaactttca
    78781 aagtaaaagg aacagacaag gaatttacag tctttactac tcgtccggac acacttttcg
    78841 gtgcgacttt cactgttttg gctcctgaac atgaattagt agatgccatc acaagcacag
    78901 agcaagcaga agcagtagca gactacaaac accaagccag ccttaagtca gacttggctc
    78961 gtaccgacct tgccaaagaa aaaactggtg tatggactgg tgcttatgcc atcaatcctg
    79021 tcaatggtaa ggaaattcca atctggattg cggattacgt tcttgctagc tatggtacag
    79081 gtgcggtaat ggctgtgcct gcccacgatc aacgtgactg ggaatttgcc aaacaatttg
    79141 accttccaat cgtcgaagta cttgaaggtg gaaatgttga agaagctgcc tacacagaag
    79201 atggccttca cgttaattca gacttcctag atggactcaa caaagaagac gctattgcca
    79261 agattgtggc ttggttggaa gaaaaaggct gtggacaaga gaaggtaacc taccgtctcc
    79321 gcgactggct ctttagccgt caacgttact ggggtgagcc aatcccaatc attcattggg
    79381 aagatggaac ttcaacagct gtccctgaaa gtgaattgcc acttgtcttg cctgtaacca
    79441 aggatatccg tccctcaggt actggtgaaa gtccactagc taacttgaca gactggcttg
    79501 aagtgactcg tgaagatggt gtcaaaggtc gtcgtgaaac aaatactatg ccacaatggg
    79561 caggttcaag ctggtactac ctccgctata ttgacccaca caatactgag aaattggctg
    79621 acgaggatct gctcaaacaa tggttgccag tagatatcta cgtgggtggt gcggaacatg
    79681 ctgtacttca cttgctttac gctcgtttct ggcataaatt cctctatgac ctcggtgttg
    79741 ttccaactaa ggaaccattc caaaaactct ttaaccaagg aatgattttg ggaacaagct
    79801 atcgtgacca ccgtggggct cttgtggcga ctgacaaggt tgaaaaacgt gatggttctt
    79861 tcttccatgt ggaaacaggg gaagagttgg agcaagcgcc agccaagatg tctaaatcgc
    79921 tcaagaacgt tgttaaccca gacgatgtgg tggaacaata cggtgccgac actcttcgtg
    79981 tttatgaaat gtttatggga ccacttgatg cttcgattgc ttggtcagaa gaaggtctag
    80041 aaggaagccg taaattcctt gaccgtgttt accgtttgat tacaagcaag gaaattgttg
    80101 cggaaaacaa tggcgctctc gacaaagttt acaacgaaac cgttaaagct gtcacagaac
    80161 aaattgagtc cctcaaattc aacacagcca ttgctcaact tatggtcttt gtcaacgctg
    80221 ccaacaagga agacaaactt tatgtagact acgccaaagg cttcgttcag ttgattgctc
    80281 catttgctcc tcacttggca gaagagctct ggcaaacagt tgcagcaaca ggagaatcta
    80341 tctcttatgt agcttggcca acttgggatg aaagcaaatt agttgaagac gaaatcgaaa
    80401 tcgtcgtcca aatcaaaggt aaagtccgtg ccaaactcat ggttgctaaa gacctgtcac
    80461 gcgaagaatt gcaagaaatt gctctcgctg atgaaaaagt caaggtagaa attgacggta
    80521 aggaaatcgt gaaagtgatt gcggtaccta acaaactcgt taatatcgtc gttaaataac
    80581 gagtttatta gctctatctg ccaccttcaa tagtccactg gactattgaa gccaactaaa
    80641 ttggttaata ttgttgtgaa ataagatagg aatccttcag agtagaatct gggggatttt
    80701 ttgaatcttc ttatgaaagt atgttatact atggtcaact ataaaatttg aaaagcgaaa
    80761 caaggggaaa gttatgccag taaatgaata tggtcagatg attggtgagt caatggaagg
    80821 ttatacacct ggtgcactgc cttctattga tttcttagaa gggcgttatg ctcgaataga
    80881 agctctttca gtggaaaagc atgcggagga tttattagct gtttatggcc ctgatacgcc
    80941 tcgggaaatg tggacctacc tctttcagga atcagtggca gatatggagg agctggttag
    81001 ccttttaaat cagatgttgg ctcgtaagga ccgtttttac tatgcaatca tagacaaggc
    81061 aactggtaag gctttgggaa ctttttctct catgcgtatt gaccagaata atcgagtaat
    81121 agaagtggga gctgtcactt tttctccaaa actcaggggg acacggatag ggacagaagc
    81181 ccagtatcta ctggcgcgct atgtctttga agagcttaac tatcgtcgct atgagtggaa
    81241 atgtgattct cttaatctgc catccagacg agcagcggaa cgtttgggat ttgtctatga
    81301 aggaaccttc cgtcaggcag tggtttataa ggggcgtacg agggatacgg attggttgtc
    81361 tatgattgat aaggactggc ctcaagtcaa agctcgattg gaagcatggc tgactcctga
    81421 aaattttgat aaaactgggc aacaatacaa gagtttgaga gaactttaag aggtgttgag
    81481 atgattacta ttaaaaagca agaaattgtc aagctagagg atgttttgca tctctatcag
    81541 gctgtcggtt ggacaaatta tacccatcaa ccagagatgc tggagcaggc cttatctcat
    81601 tcattagtga tttatgtggc gcttgatggt gatgctgtag tgggcttgat tcgtttggtt
    81661 ggagatggtt tttcatcagt ttttgtacag gatttgattg ttttgcctaa ctatcagcgc
    81721 caagggattg gtagtctctt gatgaaagag gctttaaaag attacaaaga tgcctatcaa
    81781 gtccagctgg tgacagaaga gacagaaaaa aacgtaagat tttatcgttc tatgggtttt
    81841 gaagccttat ccacctatga ttgtatagga atgacttggg tgaatcgaga aaaataacaa
    81901 aacttgtttt ttcttaagca aagtttaagg atggtctagt atcatatagt cattaaataa
    81961 agacctccta actttattta ataaaatcct aaactttttt catcacaatc tcctaatgaa
    82021 gccacccaat caggtggctt ttttgcgtgg tgaggtgctg gtgatagaaa ttttttgcaa
    82081 aatagtaaaa ttttagaaaa gttaagctag t
//
LOCUS       DAVLIK010000002        78820 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLIK010000002 DAVLIK010000000
VERSION     DAVLIK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 78820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78820
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.002"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(47..1936)
                     /locus_tag="VXE87_000098"
     CDS             complement(47..1936)
                     /locus_tag="VXE87_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0841723.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSSFERDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2074..3639
                     /locus_tag="VXE87_000099"
     CDS             2074..3639
                     /locus_tag="VXE87_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0841724.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3639..4379
                     /locus_tag="VXE87_000100"
     CDS             3639..4379
                     /locus_tag="VXE87_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0841725.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(4488..4703)
                     /locus_tag="VXE87_000101"
     CDS             complement(4488..4703)
                     /locus_tag="VXE87_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841726.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(5574..6824)
                     /gene="ilvA"
                     /locus_tag="VXE87_000102"
     CDS             complement(5574..6824)
                     /gene="ilvA"
                     /locus_tag="VXE87_000102"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0841727.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(6874..7230)
                     /locus_tag="VXE87_000103"
     CDS             complement(6874..7230)
                     /locus_tag="VXE87_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0841728.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7468..7704)
                     /locus_tag="VXE87_000104"
     CDS             complement(7468..7704)
                     /locus_tag="VXE87_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841729.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7811..8833)
                     /gene="ilvC"
                     /locus_tag="VXE87_000105"
     CDS             complement(7811..8833)
                     /gene="ilvC"
                     /locus_tag="VXE87_000105"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0841730.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(8899..9375)
                     /gene="ilvN"
                     /locus_tag="VXE87_000106"
     CDS             complement(8899..9375)
                     /gene="ilvN"
                     /locus_tag="VXE87_000106"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0841731.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9368..11068)
                     /locus_tag="VXE87_000107"
     CDS             complement(9368..11068)
                     /locus_tag="VXE87_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0841732.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11269..12936)
                     /locus_tag="VXE87_000108"
     CDS             complement(11269..12936)
                     /locus_tag="VXE87_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0841733.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALRD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(12939..13304)
                     /locus_tag="VXE87_000109"
     CDS             complement(12939..13304)
                     /locus_tag="VXE87_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0841734.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13461..13649)
                     /locus_tag="VXE87_000110"
     CDS             complement(13461..13649)
                     /locus_tag="VXE87_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0841735.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13765..13941)
                     /locus_tag="VXE87_000111"
     CDS             complement(13765..13941)
                     /locus_tag="VXE87_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0841736.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(14052..14250)
                     /locus_tag="VXE87_000112"
                     /pseudo
     CDS             complement(14052..14250)
                     /locus_tag="VXE87_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(14505..16049)
                     /locus_tag="VXE87_000113"
     CDS             complement(14505..16049)
                     /locus_tag="VXE87_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0841737.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVSGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16262..16564
                     /gene="gatC"
                     /locus_tag="VXE87_000114"
     CDS             16262..16564
                     /gene="gatC"
                     /locus_tag="VXE87_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0841738.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            16564..18030
                     /gene="gatA"
                     /locus_tag="VXE87_000115"
     CDS             16564..18030
                     /gene="gatA"
                     /locus_tag="VXE87_000115"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0841739.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18030..19472
                     /gene="gatB"
                     /locus_tag="VXE87_000116"
     CDS             18030..19472
                     /gene="gatB"
                     /locus_tag="VXE87_000116"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0841740.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19601..20161
                     /gene="efp"
                     /locus_tag="VXE87_000117"
     CDS             19601..20161
                     /gene="efp"
                     /locus_tag="VXE87_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0841741.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20183..20572
                     /locus_tag="VXE87_000118"
     CDS             20183..20572
                     /locus_tag="VXE87_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0841742.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20565..20987
                     /gene="nusB"
                     /locus_tag="VXE87_000119"
     CDS             20565..20987
                     /gene="nusB"
                     /locus_tag="VXE87_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0841743.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21036..21413)
                     /locus_tag="VXE87_000120"
     CDS             complement(21036..21413)
                     /locus_tag="VXE87_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0841744.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYLMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21776..21961)
                     /gene="briC"
                     /locus_tag="VXE87_000121"
     CDS             complement(21776..21961)
                     /gene="briC"
                     /locus_tag="VXE87_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0841745.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22120..22887)
                     /locus_tag="VXE87_000122"
     CDS             complement(22120..22887)
                     /locus_tag="VXE87_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0841746.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(22884..23750)
                     /locus_tag="VXE87_000123"
     CDS             complement(22884..23750)
                     /locus_tag="VXE87_000123"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0841747.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(23787..25154)
                     /gene="accC"
                     /locus_tag="VXE87_000124"
     CDS             complement(23787..25154)
                     /gene="accC"
                     /locus_tag="VXE87_000124"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0841748.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25166..25588)
                     /gene="fabZ"
                     /locus_tag="VXE87_000125"
     CDS             complement(25166..25588)
                     /gene="fabZ"
                     /locus_tag="VXE87_000125"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0841749.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(25585..26070)
                     /locus_tag="VXE87_000126"
     CDS             complement(25585..26070)
                     /locus_tag="VXE87_000126"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0841750.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26073..27308)
                     /gene="fabF"
                     /locus_tag="VXE87_000127"
     CDS             complement(26073..27308)
                     /gene="fabF"
                     /locus_tag="VXE87_000127"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0841751.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27330..28061)
                     /gene="fabG"
                     /locus_tag="VXE87_000128"
     CDS             complement(27330..28061)
                     /gene="fabG"
                     /locus_tag="VXE87_000128"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0841752.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(28095..29015)
                     /gene="fabD"
                     /locus_tag="VXE87_000129"
     CDS             complement(28095..29015)
                     /gene="fabD"
                     /locus_tag="VXE87_000129"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0841753.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29008..29982)
                     /gene="fabK"
                     /locus_tag="VXE87_000130"
     CDS             complement(29008..29982)
                     /gene="fabK"
                     /locus_tag="VXE87_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0841754.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30101..30325)
                     /locus_tag="VXE87_000131"
     CDS             complement(30101..30325)
                     /locus_tag="VXE87_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0841755.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30385..31359)
                     /locus_tag="VXE87_000132"
     CDS             complement(30385..31359)
                     /locus_tag="VXE87_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0841756.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31359..31793)
                     /locus_tag="VXE87_000133"
     CDS             complement(31359..31793)
                     /locus_tag="VXE87_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0841757.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(31887..32672)
                     /locus_tag="VXE87_000134"
     CDS             complement(31887..32672)
                     /locus_tag="VXE87_000134"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0841758.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            32997..34361
                     /locus_tag="VXE87_000135"
     CDS             32997..34361
                     /locus_tag="VXE87_000135"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0841759.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34364..34735
                     /locus_tag="VXE87_000136"
     CDS             34364..34735
                     /locus_tag="VXE87_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0841760.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            34949..36223
                     /gene="serS"
                     /locus_tag="VXE87_000137"
     CDS             34949..36223
                     /gene="serS"
                     /locus_tag="VXE87_000137"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0841761.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36244..37146)
                     /locus_tag="VXE87_000138"
     CDS             complement(36244..37146)
                     /locus_tag="VXE87_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0841762.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKRSS"
     gene            complement(37256..37804)
                     /locus_tag="VXE87_000139"
     CDS             complement(37256..37804)
                     /locus_tag="VXE87_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0841763.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38022..39344)
                     /locus_tag="VXE87_000140"
     CDS             complement(38022..39344)
                     /locus_tag="VXE87_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0841764.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39435..39523)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(39687..42023)
                     /locus_tag="VXE87_000141"
     CDS             complement(39687..42023)
                     /locus_tag="VXE87_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0841765.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYTNLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42127..42675)
                     /locus_tag="VXE87_000142"
     CDS             complement(42127..42675)
                     /locus_tag="VXE87_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0841766.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(42672..42974)
                     /gene="zapA"
                     /locus_tag="VXE87_000143"
     CDS             complement(42672..42974)
                     /gene="zapA"
                     /locus_tag="VXE87_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0841767.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43061..43942
                     /locus_tag="VXE87_000144"
     CDS             43061..43942
                     /locus_tag="VXE87_000144"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0841768.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            43946..44560
                     /gene="lepB"
                     /locus_tag="VXE87_000145"
     CDS             43946..44560
                     /gene="lepB"
                     /locus_tag="VXE87_000145"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0841769.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            44688..47054
                     /locus_tag="VXE87_000146"
     CDS             44688..47054
                     /locus_tag="VXE87_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0841770.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTKKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(47102..48385)
                     /locus_tag="VXE87_000147"
     CDS             complement(47102..48385)
                     /locus_tag="VXE87_000147"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0841771.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(48546..48938)
                     /locus_tag="VXE87_000148"
     CDS             complement(48546..48938)
                     /locus_tag="VXE87_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0841772.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(49237..49866)
                     /locus_tag="VXE87_000149"
     CDS             complement(49237..49866)
                     /locus_tag="VXE87_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0841773.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(49911..50150)
                     /locus_tag="VXE87_000150"
     CDS             complement(49911..50150)
                     /locus_tag="VXE87_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841774.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(50300..50566)
                     /locus_tag="VXE87_000151"
                     /pseudo
     CDS             complement(50300..50566)
                     /locus_tag="VXE87_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(50591..50902)
                     /locus_tag="VXE87_000152"
     CDS             complement(50591..50902)
                     /locus_tag="VXE87_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0841775.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(50827..51069)
                     /locus_tag="VXE87_000153"
                     /pseudo
     CDS             complement(50827..51069)
                     /locus_tag="VXE87_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(51070..51702)
                     /locus_tag="VXE87_000154"
     CDS             complement(51070..51702)
                     /locus_tag="VXE87_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0841776.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF"
     gene            complement(51716..52711)
                     /locus_tag="VXE87_000155"
     CDS             complement(51716..52711)
                     /locus_tag="VXE87_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0841777.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHNLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(52708..53406)
                     /locus_tag="VXE87_000156"
     CDS             complement(52708..53406)
                     /locus_tag="VXE87_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0841778.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(53483..54493)
                     /locus_tag="VXE87_000157"
     CDS             complement(53483..54493)
                     /locus_tag="VXE87_000157"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0841779.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(54477..55484)
                     /locus_tag="VXE87_000158"
     CDS             complement(54477..55484)
                     /locus_tag="VXE87_000158"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0841780.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(55471..56424)
                     /gene="mvaD"
                     /locus_tag="VXE87_000159"
     CDS             complement(55471..56424)
                     /gene="mvaD"
                     /locus_tag="VXE87_000159"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0841781.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(56406..57284)
                     /gene="mvk"
                     /locus_tag="VXE87_000160"
     CDS             complement(56406..57284)
                     /gene="mvk"
                     /locus_tag="VXE87_000160"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0841782.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(57406..57735)
                     /locus_tag="VXE87_000161"
     CDS             complement(57406..57735)
                     /locus_tag="VXE87_000161"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0841783.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWAQ"
     gene            58398..58756
                     /locus_tag="VXE87_000162"
                     /pseudo
     CDS             58398..58756
                     /locus_tag="VXE87_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            58656..59126
                     /locus_tag="VXE87_000163"
     CDS             58656..59126
                     /locus_tag="VXE87_000163"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841784.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            59285..60517
                     /locus_tag="VXE87_000164"
     CDS             59285..60517
                     /locus_tag="VXE87_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0841785.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(60635..61633)
                     /gene="cbpJ"
                     /locus_tag="VXE87_000165"
     CDS             complement(60635..61633)
                     /gene="cbpJ"
                     /locus_tag="VXE87_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0841786.1"
                     /translation="MKLLKKMMPIALAVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQYLGNKWYYLRSSGAMVTGW
                     YQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYYVNYNGEWVR"
     gene            complement(61732..62421)
                     /locus_tag="VXE87_000166"
     CDS             complement(61732..62421)
                     /locus_tag="VXE87_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0841787.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(62433..63857)
                     /gene="gndA"
                     /locus_tag="VXE87_000167"
     CDS             complement(62433..63857)
                     /gene="gndA"
                     /locus_tag="VXE87_000167"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0841788.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(63933..65327)
                     /gene="mapZ"
                     /locus_tag="VXE87_000168"
     CDS             complement(63933..65327)
                     /gene="mapZ"
                     /locus_tag="VXE87_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0841789.1"
                     /translation="MSKKRRNRHKKEAQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(65340..66497)
                     /locus_tag="VXE87_000169"
     CDS             complement(65340..66497)
                     /locus_tag="VXE87_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0841790.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     TIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIESVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(66582..66962)
                     /gene="rnpB"
                     /locus_tag="VXE87_000170"
     ncRNA           complement(66582..66962)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXE87_000170"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(66983..67324)
                     /gene="gpsB"
                     /locus_tag="VXE87_000171"
     CDS             complement(66983..67324)
                     /gene="gpsB"
                     /locus_tag="VXE87_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0841791.1"
                     /translation="MTSIIFSAKDIFEQEFGREVRGYSKVEVDEFLDDVIKDYETYAT
                     LVKSLRQEIADLKEELTRKPQVSSAPSPSHPDPIDVAASSSMTNFDILKRLNRLEKEV
                     FGKQILDNTDL"
     gene            complement(67394..67921)
                     /locus_tag="VXE87_000172"
     CDS             complement(67394..67921)
                     /locus_tag="VXE87_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0841792.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            67988..68584
                     /gene="recU"
                     /locus_tag="VXE87_000173"
     CDS             67988..68584
                     /gene="recU"
                     /locus_tag="VXE87_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0841793.1"
                     /translation="MVNYPHKLSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            68581..70740
                     /locus_tag="VXE87_000174"
     CDS             68581..70740
                     /locus_tag="VXE87_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV0841794.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     SIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEQETGYNLLTTGMDVYTNVDQEAQKHLWDIYNSDQYVSYPDDDLQVASTVV
                     DVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSAMKPITDYAPAIEYGVYDSTAT
                     MVNDIPYNYPGTSTPVYNWDRAYFGNITLQYALQQSRNVTAVETLNKVGLDRAKTFLN
                     GLGIDYPSMHYANAISSNTTESNKQYGASSEKMAAAYAAFANGGIYHKPMYINKVVFS
                     DGSKKEFSDVGTRAMKETTAYMMTEMMKTVLAYGTGRGAYLPWLAQAGKTGTSNYTDD
                     EIEKHIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPIVGDGFLVAAKVYRSMITY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSN
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(70907..76210)
                     /locus_tag="VXE87_000175"
     CDS             complement(70907..76210)
                     /locus_tag="VXE87_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0841795.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKHAAAKPETLKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLIQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FESLDAPAQPGEGLENAFDGNVSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(76511..78493)
                     /locus_tag="VXE87_000176"
     CDS             complement(76511..78493)
                     /locus_tag="VXE87_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0841796.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKTQEDLAKHVK"
BASE COUNT        22908 a        17987 c        14563 g        23362 t
ORIGIN      
        1 tctatcttcc attatatcat actttttcag tctatggtag ctctctttaa aaggctccga
       61 tactgccgcc acctccgcct ccagagaagc caccgccaga acttccactt ccagaagata
      121 cggagtaggt acttgctgta tttgcgacac tagcataatg gctcatttgc gcgcttgaat
      181 gataaaacat actgtgccag ccataagcta catagagatt gatatctgga ttttcaactt
      241 gaatctgatg aaccttcatc aaatgactaa ccttgtccgc atagccaaat aaggttgcat
      301 agaccaagag acgattccaa acaacaatac tttccaattc agccttatcc agtcgtgcaa
      361 tctcacgtaa catattttca aaactggtcc agagatagta gacctcagct cccgcttcat
      421 ttagaacacc atcacgatta tctagtcgaa gcttccaata atagaaaaca gacaaaacta
      481 accctagaaa accaagtatt ggcaaaggga ggtaaagata gccatgaacg tctaaactgt
      541 acaagaacaa accaaatccg ataaataggg gcaggatagt caaggcaccc atacccactt
      601 gcaaggcctt ttccccacca gttaaaggac gataataatc tgggagcccc cagaaggaaa
      661 ctcgttttct cactccttct tgcatctggt tcaatacctc ttcaaaagaa gatttgagtt
      721 gaagccctct tgcttgaatc cgtttttcat cagaaacttt ggctctacga taaagactat
      781 cagatacctt gtaatccgca aacaaattgg aaagagtttc ttctttttta cctgaaaaag
      841 ctagatttag gcagtctctc tcaaagcttg acaaaccatc ttcttttact agcctcaaac
      901 caactgcatc tccttctgaa ataatagaaa cattcccacg gtccatcaca tctagcaagg
      961 tagcttgaat aagttggtca aaagtgaatt tgccagcccc cttgactaag ggactcactt
     1021 cctccaagga ggtcgagtag acagcctctg ataaaaccat aggctctaat tccattggtg
     1081 gttcatagag acgatgattt ttggcatatt tgactgaagg agtggtcttt cttctataaa
     1141 taaaatagaa gcagacactc aataacaagg agatagaaag gatcgaaggg aggacccaag
     1201 taacaagttg tttactctga tctttttctc taacaatcga gtcttctatc ttattaaact
     1261 cttctaaacg attccctttc aatccctgat ccctagcgct agcaaaatcg gtccgaggcc
     1321 agtaggcatg caactcaact ccacgcttag ccggaagatt gtctaaacgg atagtataat
     1381 caaggttact cttttcaatc gttccctctc taaaaagttt ccctgtatgg aaaaagagtt
     1441 tttcagcccc cttgtctccc cttacatgaa attcaaactt ttcaatagac tctgaactat
     1501 ctgtcagagg ttgccaattt aattcagcga tatcatcata aaggaaaagt aaatttttta
     1561 agttccagac gaggtcaact tcaactatgt cgccctcctg acctggatta tagactctca
     1621 cagtataacc atccgcttct tctgttactt cgctagtcac atctgctagt tctgcaccgt
     1681 ttttcgcggc ctgaaccttt ggatgagggt caatgtcaaa cccgctaggc atcttaccag
     1741 cacgtccaag tcccacgatt tgtcccttaa agtcctcctc aaactggtaa actatcttct
     1801 gtctaaactc tgccgtatta tctgcatgaa tatacaaatc cccttgataa gagtttatct
     1861 tgaaatcaat ggcaaaaaca gagagtggaa gaaggcaaaa caagcctaac accagtaaga
     1921 aaaaagtttt tttcatcaac taagccccct ttttatcttt cttatcatta tagcattttt
     1981 tcgtaagtaa aggcttactt atgttgaaaa attacgcatt tttcgataaa ataggagaca
     2041 gttatttttt aatagatcag aataggagaa atcatgagaa aaatatactt atctattttc
     2101 acaagtctct tgctgatgct aggacttgtc aatgttgctc aagccgatga atatttacgc
     2161 atcgggatgg aagcagcata tgctcccttt aactggaccc aggatgatga tagcaacgga
     2221 gctgtcaaaa tcgatgggac caatcagtat gccaacggat acgatgttca aatcgccaag
     2281 aaaatcgcta aggacttagg taaagaacct ttggttgtta aaaccaagtg ggaaggtcta
     2341 gtccctgccc ttacttctgg taagattgac atgattatcg caggtatgag tccaactgca
     2401 gaacgcaaac aagaaattgc cttttcgagc agttactaca ctagcgaacc agttttgctt
     2461 gtcaaaaaag attctgccta cgcaagtgct aaatctttgg atgactttaa cggtgcaaaa
     2521 atcacttctc aacaaggggt ctacctctac gacttgattg cacaaatccc aggtgctaaa
     2581 aaagaaacag ccatgggaga cttcgctcaa atgcgacaag ctcttgaggc tggtgtcatt
     2641 gatgcttatg tttctgaacg tccagaagca ctgactgctg aagctgcgaa ctctaagttc
     2701 aagatgattc aagtagaacc tggtttcaaa actggggaag aagatacagc tatcgctatc
     2761 gggcttcgta aaaatgacaa tcgtattagc caaatcaatg ccagcattga aaccatttca
     2821 aaagatgacc aagttgcctt gatggatcgt atgatcaagg aacaacctgc cgaagctaca
     2881 acaactgaag agactagcag tagtttcttt agccaagtcg ctaaaattct ttctgaaaac
     2941 tggcaacaac tcttgcgtgg tgctggtatc actcttttaa tctctatcgt cggaaccatc
     3001 ataggtctca ttattggact tgccattggt gtcttccgta ctgctcctct ctctgaaaac
     3061 aaagccattt atggccttca aaaactagtc ggctgggttc tcaatgtcta cattgaaatt
     3121 ttccgtggta cgccaatgat tgttcaatcg atggttatct actatggaac tgcccaagct
     3181 ttcgggatca accttgaccg tacactggct gctatcttca tcgtttcaat caataccggt
     3241 gcctacatga ctgaaatcgt ccgtggtggt atcctagcag ttgacaaggg acaatttgaa
     3301 gctgcgactg ctcttggtat gacccataac cagaccatgc gtaagattgt cctacctcag
     3361 gtagtccgta acatcctacc tgcaactggt aatgaatttg tcatcaatat caaagataca
     3421 tctgtattga acgttatctc tgttgtcgaa ctttatttct caggaaatac cgtggcaaca
     3481 caaacctatc aatacttcca gacatttaca atcatcgccg tgatttactt tgtcctcacc
     3541 ttcaccgtaa cacgtatcct acgctttatc gagcgcagaa tggacatgga tacctacact
     3601 acaggtgcta accaaatgca aacggaggat ttgaaataat gacacaagca atccttgaaa
     3661 ttaaacacct caaaaaatcc tatggacaaa acgaagtgct aaaagacatt tcactcactg
     3721 tccacaaggg agaggtcatc tctatcatcg gaagctctgg aagcggaaaa tcgaccttcc
     3781 tacgctccat taacctactt gaaacaccaa ctgatggaca aatcctttat catggacaaa
     3841 acgtcctcga aaaaggctat gacctcacgc aataccgtga aaagttgggg atggttttcc
     3901 aatcctttaa cctctttgaa aatctcaatg ttcttgaaaa cacaatcgtc gctcagacaa
     3961 ctgtcctaaa acgcgaacgc acagaagctg aaaagattgc caaagaaaac ctggaaaagg
     4021 tcggcatggg agaacgctac tggcaagcca aaccaaaaca actctcaggt ggtcaaaaac
     4081 aacgtgtggc catcgctcgt gccctctcca tgaatccgga cgccattctc tttgatgaac
     4141 caacatcagc tctcgatcca gaaatggttg gagaagtcct caaaatcatg caggacctgg
     4201 ctcaggaagg cttgaccatg attgtcgtaa cccatgaaat ggaatttgcc cgtgatgtct
     4261 ctcaccgtgt tatctttatg gataagggcg tgatcgctga agaaggtaaa ccagaagacc
     4321 tcttcaccaa tcctaaagaa gaccgaacaa aagagttcct tcaacgctat ctcaaataaa
     4381 aagaaaaggc tgcatcaacc gtgcagtctt tttgctgtcc tcaaaatgaa aaggcagatt
     4441 ctctatctct actacttgaa ggtcaagaat ccgccgttat ccaaagatta atcttcaaat
     4501 ttttcataat ttttttcata gaaatcaatt aggcctaggg ctgtttcaaa tgaaatattt
     4561 tttacttttg cacgaccctg cgccagagca atgatagaca tttcacgcgc attcgtttct
     4621 ttagagatac ggtagcctgt gattttctta tcacgaaccc agccaacaac tgattctact
     4681 ttttcaaagt ttgacttagc catgtttttc tcctattttc ttctttataa tatttaattg
     4741 tatacgtttt tactactttt gtcaataaaa aaaacatata ttcaacgaaa ataattagtt
     4801 cagaattttc ttacttcctt tttaaatccg ataatatata ggttttgcta gcctctacac
     4861 cataaatatt tgctaataaa actactgtat tattaccctc ttaaggtgcg aaattattca
     4921 agttcttaaa aaatgcttct ctatttccgt aagatagctt atttcttcga tttaagaact
     4981 gaagatgata gttctaacct ttagaaatcc aagccttcac tagctcaaaa actcctatct
     5041 ttcttcctca ataaatcatc tgagagatag gtattcctta tatccttcaa attcatcact
     5101 cctttggata ttgaggtgct agcctagaag cagacacccg attatctaaa ccatccttaa
     5161 tagagatgac aagacagata agctcagtta attacttata tatcttttta atatggtata
     5221 tttgtcaaca aaaagaaatc aaatcatacc ttatactcaa tgaaaatcaa agagcaaact
     5281 aggaagctag ccgcaagttg ctcaaaacac tgttttgagg ttgcagatag agctaacgtg
     5341 gtttgaagag attttcgaag agtattaaag acagtgtgac tatgcttgtc aatagatagg
     5401 aaatcaaaat gaaggatgga aatctgagcc aaacatcata agtgctataa tgaacagaag
     5461 taagaattgc acgataagtt ttctaaaacc ataggaatcg tcccctttct tcatcttcat
     5521 tatagcacat atacatcagt tgtacaaata atatgatatt tttttattag tcctcagaca
     5581 agcatattat aaagcgtttc attaccattt aagttaatat aagctggatc aaaaccttcc
     5641 attctacgaa tcaaacctgc ataatcatgc ttatctgcta aagcgatccc aattaatact
     5701 gggcctgttc ccttgctagc tcgtttgata tactcaaaac gtgtgatatc atcatttggc
     5761 cccaggatat catttacaaa ctcacgcaaa gctcctggac gttgtgggaa attgaccaca
     5821 aagtaatgtt tgataccatc ataaatcaag gcacgctctt ccatttctgg catacggttg
     5881 atatcattat ttcctccaga aatgatacaa caaatggttt tccccttaat atattcagct
     5941 aaaacctcta aagaggcgat actagccgct ccagcaggtt ctgcgactat cccttgctta
     6001 gagtaaaggt caatcaaggt ttcagaaatc aatccctcat cgacacctac caaagtttta
     6061 atatgttgac gagttgcttc ataggtcaac tgacctacct tttgcacagc aatcccatcc
     6121 gcaaatttat caatttcctt gagtttgact ggacctccag cctcaaaggc agctttcatg
     6181 gaacgcgctc cattcgcctc tactccgata acctcaatct ctggacttgt ttccttgata
     6241 taggtagaaa ccccggcaat gagaccgcca ccaccaacag gaaccaagac agcatcaaaa
     6301 tcaatcgatt cttttcgagc ttcttctaaa atctcataag caactgttcc ttgacctgct
     6361 tgaacatgag catcatcaaa aggatcaata aaggtacgat tttcagagac tgtaaattct
     6421 tgagctgctt tggctgaggc atcaaaggta tctccaacta gtttaatagt tacaaaatcc
     6481 ccaccaaaaa agcgaacctg accaatcttt tgttgtggcg tagtaatagg cataaagata
     6541 gtagcaggaa ttttcatttc attacaagta taggctactc cctgcgcatg atttcccgca
     6601 gaagcgcaga ctaccccacg ttcacgttct tccttgctga gctgggaaat ggcataatag
     6661 gcaccacgaa ttttaaagga gcgaacacgc tgggcatttt cttttttcaa ataaatctta
     6721 gcaccatact tctccgataa ataatgatcg taatccagtg gagtattcac aaccacaccg
     6781 ttcaagacct tgtgagcctt gattatatct tttgaactta acatataaaa cctctttttc
     6841 tataaaaaac agtcactaat gactgttttt tagttattca tctccgaaaa cttcagtaac
     6901 actttcatgg tatttatgag ccatacgaat cgaaaactct ttaggaagtt cataacgatt
     6961 tgtggaaatc caatcatata accattctac caaactttct tcactatcat tacgatggaa
     7021 gataaaatag tttaaaattt ctttatattc tacatcattc aaatccaacg tgtctacaaa
     7081 ttgactacga ggaacaaaat tagaatctaa ttttcttagt tgatctgtca attctcccaa
     7141 ttgtaaatcc aactgaaaaa atagtttttg cagttgccta tcagtttcat cacatcctgt
     7201 cttgatagaa aacaaattgg taatattcat atgatttcaa cccctaaata agtacatcta
     7261 atatcccacg aatagctgaa gctaaagttt tcgcagtcca gtcatttaaa cccgattctt
     7321 tcaatccaga tgcaataatt tgctctattt gatataaacc gccatctatc gtctcattta
     7381 ttctgcgaag aggaccttca atataggata aagcttctcc gaatctaaca gctgatttag
     7441 gtcctaatga tttaccaact atatttgtta atgtttttta tttctcaaaa tccatttcgc
     7501 tatataacga gcagatttag tcgcaccagc tctctcaaac ggagaatgaa tttcaagacc
     7561 ttcttctcta gctatttgtg ccaatttgaa gaattgttca aaggtcatat gcaacctacc
     7621 atcttcaaaa ttagcatcat cataaatgtt aattacagca ttttcatcat acgaccaatc
     7681 tgctttattt tggtctgcta gcactattac cgacggtgta attacattat acaactagaa
     7741 ccaataataa cgatgcaatt tttctcataa tctttttcat aaaatcatct ccagcgctat
     7801 atatttctaa ttagttatag attttgaatg catcatcgtc gtttttacca acgaatggca
     7861 ttgctttacg caattctgca ccaacttttt caatttcaag gttagctgct tgttcacggt
     7921 aagcagtcaa ttttggacgt ccagctttat agtcatttac aaagtcattt gcaaatttac
     7981 cattttggat gtctgccaag acagccttca tattttcttt aacttgttca gtgattacac
     8041 gtggacctga tacatagtca ccgtattcag cagtgtttga aatagattga cgcattttct
     8101 tgaatccacc ttcatagatc aagtcaacga tcaatttcat ttcgtgaaga acttcaaagt
     8161 aagccaattc tggagcgtaa cctgcttctg tcaagacttc gaaacctgct tcgataaggg
     8221 cagtcaaacc accacaaagt acagcttgtt caccaaacaa atcttcttca gtttcttctt
     8281 tgtaagttgt ttcaagaaga cctacacgag ccgctccaac acctttacac cagtccatag
     8341 caatgttttt agcatttcct gttgcatctt ggtatactgc ataaagagct ggaacaccaa
     8401 atccttcttc gtaagtacga cgtaccaagt gtcctggtcc tttaggagca cacatgaaga
     8461 catctacatc cgcaggaact ttgataaatt caaagtggat gttgaaacca tgggcaaatc
     8521 caactgcgtt tccagcttcc aagtttggag cgatttctgc ttcgtacaat tcttgttgaa
     8581 tttcgtctgg cgccaagatc atgataacat cagccaactt agtagcttct gctactgtgt
     8641 aagtatcaaa tccatcttct tttgctttat caaaagattt acctggacgt acacctataa
     8701 taacgtcacg acctgaatca cgcaagtttt gagcatgcgc atgcccttgt gaaccataac
     8761 cgataacggc gattttttta ccgtcaagtg ctgctacttt aacatctttt tcatattcca
     8821 tttgaactgt catagctttt ctctcttttc tattatttat tgccttttag gctggtttaa
     8881 taaatttaag ttggattttt aatcgcgggt aaatccagtt gcacccgttc gagcaatatt
     8941 gcgaataccg tatgggcgaa tgactctcaa tagggcttcg ctcttttctg catttcccgt
     9001 catctgaatg gtaatcgagc ttggcgctac gtctaccact gttgcacgga aaggttgaat
     9061 aatcgctaaa atctcagctc tcttctcagc tggcgctgac atcttaacca aaatcacctc
     9121 gcgctccaaa tgaggcttgt ctgtaatatc tcgaatgcga atcacatcaa tctgacgatt
     9181 gagctgtttg atgatttgct ccacttcatc atgagaagca acatcaataa taatagtgat
     9241 acgcgataca ttcggatctt ctgttgctcc aacagagatg ctttcaatat taacctgacg
     9301 acgagatagg acacctgtaa agcgattgag gactcctgaa cgattttgta gttttgctgt
     9361 taacattcta cgcatggaac tgcaccccca acatctcatg attactctta ccagccggta
     9421 ccattggtaa cacctgttcc ttacgagaaa tatctacctc aattagcata ggaacatcct
     9481 cagtgatgac ttcaaggtct tgagccaagg tctcaggatt gtcaaactta tagtttttaa
     9541 tgccataagc ctgcgccatc aattggaaat caggaagggt atcaaagacc gactctgatg
     9601 ttctgccttc atagaaggat tcctgccact ggcgaaccat tccgagtgaa tgattgttca
     9661 gcataaccac cttgattggc accttgtaaa tattcaaaat agccaactcc tggttagtca
     9721 tttggaaacc accatcccca acaaacaaga ctacttcctt atctgggtta gcaattttag
     9781 caccgattgc tgctggaatt ccaaagccca ttgttcccaa accacctgaa gtcactaact
     9841 gacgttcatt ttggtaggga taatactgag ctgtccacat ttggtgttga ccaacgtctg
     9901 ttaccacaat ggcatctcca ttcgtcaatt caccaattcg ttcaataact gcttgcggtt
     9961 gaaccacacg ctctttcttg tcataagaac gaacacgatt cttgtcttta gtgactttct
    10021 caatccactt ttcagtattg ttgtgaactg ttggttctgc tagcaacatt tgcaaggcct
    10081 tcttagcatc tccaactaca ggaatgtctg cactgataat cttgccaatc tcagctgggt
    10141 caatatcaat gtgggcaacc ttagcattct tagcgaaagt cttaggattc cccgtcaaac
    10201 ggtcatcgaa acgagaacca atactaatca taaagtccgc ttccgtcatg gcaatatttg
    10261 ctgcgaatga cccgtgcatg cctcccattc caagaaagag tgggtgactc gttgcaatcg
    10321 ttccttgtcc caaaagactg gttaccactg gaatttgata gcgttctgca aattcattta
    10381 gttccgtagc agcctcagca taactaattc caccaccagc taacaagact ggctttttag
    10441 ccttggacaa ttgcttcaag attttcttga tttgcatatc attcggctca agagtcggct
    10501 gataacttgg taaattcact tctggtgaat aaatgaagtc tgtttctaaa gcagatatgt
    10561 cttttggtag gtcaattaca actggccctg gacggcctgt agttgcgata tggacagctt
    10621 ccgtaatgat acgcggaata tcagctgtct cacgaacttg gtaattgtac ttagtgattg
    10681 gcatggtaat tcctacgatg tctgcctcct gaaaggcatc cttcccaatc cctgctcgcg
    10741 ccacctgacc tgtaaagacc aaaaggggaa cgctatcgct catagcatcc gcaatccctg
    10801 taatggcatt tgttgctcct ggtccactag tgacgacggc aacacccaac tttccagttg
    10861 atttggcata accttcagct tcatgcaaac aaccttgctc atggcgccct agaatgtggc
    10921 gaatgccttt aaaattatat atcgcatcat aaaaaggcaa aaccgcacca ccaggataac
    10981 caaagatggt atcaactcct aaatcacgaa gtgtttccaa aactaggtcc gaccccgtct
    11041 taggagattc taaactgatt ttctccattg ttcccctttc tttcctctta aaaataactt
    11101 gttactatca taccattttt tcaaaatttt tcaagataaa agaagaaatt ttctgaattt
    11161 tctattttaa cgtttattta tgaatgttat ttttgttttt attaaaaaga taccgatttc
    11221 atttactaaa aaagaaaaaa gaactgattt ctcagtcctt cattaatctt attccacact
    11281 aaataggtat gggtaaacag gttgttgacc ttggtgaatc tcgacttcaa cgtcttcgaa
    11341 ttcttctacg atttcttgag cgatttcatt ggcaagttct tcgcttccgt cttcaccgac
    11401 atagaaggtt acgatttcac tgtcttcatc caacatatgt ttcaaggttt cagtcaatgt
    11461 ttggtgcata tcagggtttg acacaagaat ttttccatcc accataccta gattatcgtt
    11521 ttcatggatt tctaagccat cgatcgttgt atcacgcacg gctgttgtga cgcttccgct
    11581 aacgacatct ctaagagcag ctgtcatacg ctcttggttt tcttcaatgg acttgcttgg
    11641 atcaaaggca agaagacttg tcataccttg aggaagagtg cgagcctcta ccactactgc
    11701 tggttgctcc aaaacttctg ccgcagattg agctgccatg aagatgttct tgttgtttgg
    11761 caagaagatg atgttacggg cattgacctg ttcaacagcc ttgataaagt cttctgttga
    11821 agggttcatg gtttgaccgc cttcgataac ataatccacg ccttgagaac agaagatatc
    11881 tgctagacct ttaccagcca ccacagcaat caaagcatac tctttttctt cagccgactt
    11941 gataacttga gtagcttctt tctcaacctg tgcttcgtgt tggttacgca tattgtcaac
    12001 ttttaccttg accaagctac catatttgag accttcttgc ataacaagtc ctggatcttc
    12061 tgtatgaaca tggactttga caatttcatc atcgttaaca acgaggagag aatccccaag
    12121 ctcatccaag tagttacgga attcatcgta gtcaaaatct ttagcatagg ttggaccttg
    12181 cttaagagct accatgattt cagtacagta accaaacgtg atgtcctcag tcgctacgtg
    12241 accagctaca gacttatgat gctctacatt gatcatctca ctcatgttgg caggagtcgc
    12301 tacaaagtcc tcagatgcaa tatattcgcc agtaagggct gaaaggaaac cttcgtagat
    12361 gaagaccaat ccttgaccac ctgagtccac aacgccaact tctttcaata ctggaagcat
    12421 gtctggtgtt ttagctagag ctgttttagc accttccaag gctgcgcgca tgacttcaac
    12481 agtatcatct gtttgctcag cttttttctt agcaccgata gcagctccac gagaaactgt
    12541 caaaatcgtt ccttcaacag gtttcatcac tgccttatag gcaacttcca cacctgattg
    12601 gaaggccaga gccaagtctt gacctgttaa ctcgtcttta tccttgatag cttgggaaaa
    12661 tccacggaaa agctgagacg taatcactcc tgagttccca cgcgcaccca tcaaaagccc
    12721 tttagcaaga atgctcgcta cttctccaac tgtagaagct ggcttgtctg caacttcttt
    12781 agcaccattt tcaatggtca ttcccatatt tgtcccagta tctccatctg gaactggaaa
    12841 gacgtttaat gaattgacat attcagcttg cttattcaag cgagttgatg cagcctgcac
    12901 catttcttga aataagctag tagtaatttt tgacacggtt attctcctac aactttgata
    12961 ttttgaatgt agacatttac agtctgagca gtaattccaa gctggttttc caagctaaag
    13021 gcaacacgct cttgaatgtt ttttgacact tcactaatct ttgttccgta gcttaacacg
    13081 gtatatacat caactgcaat actgccatct tcggctgcct ttacgacgac acctttagaa
    13141 taattttcct tacctagcag ggcttggaaa ttatctttga gggcattttt actagccata
    13201 ccgaccacac caaaaatctc agttgctgct ccacctacga cggttgcaat cacttcatct
    13261 gttagttcga tttgaccatc ttttgtatta atttttacag tcatcctttt tacctcaact
    13321 agttgatact ctattttatc atatttcagc ccaagtgtaa aagcagaatg atgtatcagc
    13381 ggatatttac tctatttttc aaacgatgtt atacccacaa taaaagaaaa aagaccctaa
    13441 ggtctccttt gcttttatta ttaaacgcgt tcaactttac ctgatttcaa agcacgagct
    13501 gaagcccaaa cttttttagg tttaccatcg ataagaacag taactttttg aaggtttggt
    13561 tttacggcac gttttgtttg gttcatcgcg tgtgaacggt tgtttcctga tacagtctta
    13621 cgacctgtaa agtaacatac tttagccatt gtgttttcct cctattagat ctaatatagc
    13681 ggatgtgcta gcaccacata ccgtactatg ttatcacact ttcttgtttt ttgcaaggga
    13741 attggaagat tttttatttg tgtcttaaat caggtcttgc gtgacatttt ctgctctcca
    13801 catgccattg ttgattaaca gaacaccaga attaaaatta tgtgtataaa aatcatctct
    13861 aactgcagct aagggtatag ccgtcaagtc caaatcccac agctcatcta tcgattttct
    13921 tacaacaata tctaaatcca aatacagtac acgagactcg cttacatact ttggaataaa
    13981 atacctaaaa aagccgcata tgaaagtccc tcaaagggga gacgataacc tttcagaata
    14041 ctactgtcaa tctaaacatt cacaatctca ctattcaaag tctctagtct tttttccatc
    14101 aattggaacc attctcgcgg aaggtcatca ttaaaaacat aaaacttaag attataatag
    14161 atgaacacaa agagatttta ttgttgtttc aactttatcc atataagcat tatctgcacc
    14221 taagacaatc gcttttttct cttctttcac tctttatctc atttcttttt attcccatca
    14281 tatgtttcta cgtaaccatt attttcgccc attcgttcgt aaaaccatac cagtggagat
    14341 tttagatgaa gtcccattac ggtttacaat ttttacatta cgacacggag ttttacaaat
    14401 cgatttcatt tgccaaacgt agttagtaag gcagttagct agttcgccaa atagcgacta
    14461 gcgtccaaca atttggaact ttagttccaa ttgttggtac tgagtcacat cttctcctct
    14521 aactctacgt ctggatactt gtccgcaaac cagcggaggg caaagtcatt ttcaaagaga
    14581 aagactggtt ggtcaaaacg gtctttggct aagatattgc gacttgacga catccgttca
    14641 tccaagtcct caggcttgat ccaacgaacg gtctttttac ccattgggct catgaccact
    14701 tccgcattgt attcgccttc catacggtgt ttaaagactt caaactggag ttgaccaaca
    14761 gctcccagca tgtactcacc tgtttggtaa ttcttataaa gctgaacggc tccttcttgc
    14821 accaattgct caatcccctt gtggaaggat ttttgcttca taacattctt agcagaaact
    14881 ttcatgaaaa tttcaggagt aaaggttggc agtggttcaa attcaaactt gttttttcca
    14941 accgtcaagg tatccccaac ctgataagta ccggtatcgt aaaccccgat aatatcacct
    15001 gatacggcat tggtcacatt ctcacgactc tccgccataa actgggtaac attagatagt
    15061 ttggcaccct taccagtacg agggagattg acactcatgc cacgctcaaa ttcgcctgat
    15121 acgatacgga caaaggcaat acggtcacgg tgacgaggat ccatgttggc ttggatttta
    15181 aagacaaagc ctgagaaatc cttgtcataa ggatccacaa tttcaccgtc tgttttcttg
    15241 tgaccatgtg gttctggagc aaacttgagg aagatttcaa ggaaggtctg cacaccaaag
    15301 tttgtcaggg ctgaaccgaa aaagacaggc gtcaattctc cagccagaat agcttcctct
    15361 gaaaactcat tcccagcttc atttaaaagc tcaatgtcat ccttgacttg ctcgtagaaa
    15421 ggattgctac caaagagttt gtccccgtct tctagactgg caaaacgctc atcccctttg
    15481 taaagctcta aacgttggtt atagaggtca tacaagccct caaaggcttt ccccatcccg
    15541 ataggccagt tcatagggta gctagcaatg cccaagattt cttccaattc ttgcaagaga
    15601 tccaaaggct cacgaccgtc acggtccagc ttgttcataa aggtaaaaac tggaatgcca
    15661 cgatgtttca caacctcaaa caatttcttg gtttgagcct cgatcccctt ggcagagtcc
    15721 acgaccatga ccgcagcatc caccgccatc aaggtacgat aggtatcttc tgagaagtcc
    15781 tcgtgccctg gcgtgtctaa gatattcacg cgcttgccgt cgtagtcaaa ttgcataaca
    15841 gatgaagtaa cagaaatccc acgttgcttc tcgatatcca tccagtcaga tttagcaaaa
    15901 gtccctgttt tcttcccttt taccgtacca gcctcacgaa tctcaccccc aaagtagagt
    15961 aactgctcag tgatggttgt tttccccgcg tccgggtggg agataatggc aaaggtacga
    16021 cgtttcttaa tttcttcttg aatattcata agttctcttt ctttgattct ctatttttct
    16081 tgtttcaata gctgagaatg atttttacat tggattttac cattcctttc aacattccat
    16141 tatatcggat tttagcattt ttttcaattt ctatttcttt tcacttcccc ctcccttatt
    16201 tataggaaaa tatggtaaaa tagaacagac taaaaatcat catttcacga aaggatgcaa
    16261 gatgaaaatt acgcaagaag aggtaacaca cgttgccaat ctttcaaaat taagattctc
    16321 tgaagaagaa actgctgcct ttgcgaccac cttgtctaag attgttgaca tggttgaatt
    16381 gctgggcgaa gttgacacaa ctggtgtcgc acctactacg actatggctg accgcaagac
    16441 tgtactccgc cctgatgtgg ccgaagaagg aacagaccgt gatcgcttgt ttaaaaacgt
    16501 acctgaacaa gacaactact atatcaaggt gccagctatc ctagacgatg gaggagatgc
    16561 ctaatgactt ttaacaataa aactattgaa gagttgcaca atctccttgt ctctaaggaa
    16621 atttctgcaa cagaattgac ccaagcaaca cttgaaaata tcaagtctcg tgaggaagcc
    16681 ctcaattcat ttgtcaccat cgctgaggag caagctcttg ttcaagctaa agccattgat
    16741 gaagctggaa ttgatgctaa caatgtcctt tcaggaattc cacttgctgt taaggataac
    16801 atctctacag acggtattct cacaactgct gcctcaaaaa tgctctacaa ctatgagcca
    16861 atctttgatg cgacagctgt tgccaatgca aaaaccaaag gcatgattgt cgttggaaag
    16921 accaacatgg acgaatttgc tatgggtggt tccggtgaaa cttcacacta cggagcaact
    16981 aaaaacgctt gggaccacag caaggttcct ggtgggtcat caagtggttc tgccgcagct
    17041 gtagcctcag gacaagttcg cttgtcactt ggttctgata ctggtggttc catccgccaa
    17101 cctgctgcct tcaacggaat cgttggtctc aaaccaacct acggaacagt ttcacgtttc
    17161 ggtctcattg cctttggtag ctcattagac cagattggac cttttgctcc tactgttaag
    17221 gaaaatgccc tcttgctcaa cgctattgcc agcgaagata ctaaagactc tacttctgct
    17281 cctgtccgca tcgccgactt tacttcaaaa atcggccaag acattaaggg catgaaaatt
    17341 gctttgccta aggaatacct aggcgaagga attgatccag aggttaagga aacaatctta
    17401 aacgcggcca aacactttga aaaattgggt gctatcgtcg aagaagtcag ccttcctcac
    17461 tctaaatacg gtgttgccgt ttattacatc atcgcttcat cagaagcttc atcaaacttg
    17521 caacgttttg acggtatccg ttacggctac cgcgcagaag atgcgactaa tcttgatgaa
    17581 atctatgtaa acagccgtag ccaaggtttt ggtgaagaag tgaagcgccg tatcatgctg
    17641 ggtactttca gtctttcatc aggttactac gatgcctact acaagaaggc tggacaggtc
    17701 cgtacactta tcattcaaga tttcgaaaaa gtcttcgcgg attacgattt gattttgggt
    17761 ccaactgctc caagtgttgc ctatgacttg gattctctca accatgaccc agttgccatg
    17821 tacttagccg acctcttgac catacctgta aacttggcag gactgcctgg aatttcgatt
    17881 cctgctggat tctctcaagg tctacctgtc ggactccaat tgattggtcc caagtactct
    17941 gaggaaacca tttaccaagc tgctgctgct tttgaagcaa caacagacta ccacaaacaa
    18001 caacccgtga tttttggagg tgacaactaa tgaactttga aacagtcatc ggacttgaag
    18061 tccacgtaga gctcaacacc aattcaaaaa tcttctcacc tacttctgcc cactttggaa
    18121 atgaccaaaa tgccaacact aacgtgattg actggtcttt cccaggagtt ctaccagttc
    18181 tcaataaagg ggttgttgat gccggtatca aggctgctct tgccctcaac atggacctcc
    18241 acaaaaaaat gcactttgac cgcaagaact acttctaccc tgataatccc aaagcctacc
    18301 aaatttctca gtttgatgag ccaatcggtt ataacggctg gattgaagtc gagctagaag
    18361 acggtacgac caagaaaatt ggtatcgaac gcgcccactt agaggaagac gctggtaaaa
    18421 acacccacgg tacagacggc tactcttacg ttgaccttaa ccgccaaggg gtacctttga
    18481 ttgagattgt atctgaagcc gatatgcgtt cgccagagga ggcctatgct tatctgacag
    18541 ccctcaagga agttatccag tacgctggca tttctgacgt taagatggaa gaaggttcta
    18601 tgcgtgtgga tgccaacatc tcccttcgcc cttatggtca agaaaaattc ggtaccaaga
    18661 ctgaattgaa gaacctcaac tccttctcaa acgttcgtaa aggtcttgaa tacgaagtcc
    18721 aacgccaggc tgaaattctt cgctcaggtg gtcaaatccg ccaagaaaca cgccgttacg
    18781 atgaagctaa caaaacaacc atcctcatgc gtgtcaagga aggggctgct gactaccgct
    18841 acttcccaga accagaccta cccctctttg aaatttctga cgagtggatt gaggaaatgc
    18901 ggactgagtt gccagagttt ccaaaagaac gtcgtgcgcg ttatgtatct gaccttggtt
    18961 tatcagacta cgatgctagt cagttgactg ctaataaagt cacttctgac ttctttgaaa
    19021 aagctgttgc cctaggtggt gatgccaaac aagtctctaa ctggctccaa ggggaagtcg
    19081 ctcagttctt gaatgctgaa ggtaaaacac tggaacaaat cgaattgaca ccagaaaact
    19141 tggttgaaat gattaccatc atcgaagacg gtactatttc atctaagatt gccaagaaag
    19201 tctttgtcca tctagctaaa aatggcggtg gcgcgcgtga atacgtggaa aaagcaggta
    19261 tggttcaaat ttcagatcca gctatcttga tcccaatcat ccaccaagtc tttgccgata
    19321 acgaagctgc tgttgccgac ttcaagtcag gcaaacgtaa cgccgacaag gcctttacag
    19381 gattccttat gaaggcaacc aaaggccaag ccaacccaca agttgccctt aaactacttg
    19441 cacaggaatt ggcgaagttg aaagaaaact agacagaaca aaaccagccc taaggttggt
    19501 tttttcttct ctaccaactc ccaataacta ttttggcttt atttccagag tattttatgg
    19561 taaaatgaag agtaataata tttattaaag aggtaaaaac atgattgaag caagtaaatt
    19621 aaaagctggt atgacctttg aaacagctga cggcaaattg attcgcgttt tggaagctag
    19681 tcaccacaag ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg atgtccgtac
    19741 tggttctaca tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag ctattatcga
    19801 gactgtccca gctcaatact tgtacaaaat ggatgacaca gcatacttca tgaatacaga
    19861 aacttacgac cagtacgaaa tccctgtagt caatgttgaa aacgaattgc tttatatcct
    19921 tgaaaactct gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg tcaccgttcc
    19981 tactactgtt gagttgacag ttgctgaaac tcaaccatct atcaaaggtg ctactgttac
    20041 aggttctggc aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc cagacttcat
    20101 cgaagcagga caaaaactcg ttatcaacac tgcagaagga acttacgttt ctcgtgccta
    20161 atctctagaa agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa tcgttatcgc
    20221 cccacgtgta cttgaaaaaa tcattgctat cgctactgca aaggtagagg gtgttcactc
    20281 tttttcaaac agatcagtgt ctgataccct ttcaaaactt tcactcggcc gtggcgttta
    20341 tcttaaaaac gtggacgaag aactcacagc agatatctat ctctaccttg agtacggagt
    20401 aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg tccgtaatat
    20461 ggctgatgta gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc cagataaaac
    20521 accaaaacca gaattgaaag atctatttga cgaggacttc ctcaatgact agtccactat
    20581 tagaatctag acgccaactc cgtaaatgcg cttttcaagc tctcatgagc cttgagttcg
    20641 gtacgaatgt cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa gatacggatg
    20701 tacaacttcc agcctttttg atagacctcg tttctggtgt tcaagctaaa aaggaagaac
    20761 tagataagca aatcactcag catttaaaag taggttggac cattgaacgc ttaacgctcg
    20821 tggagagaaa cctccttcgc ttgggagttt ttgaaatcac ttcatttgac actcctcagc
    20881 tggttgctgt taatgaagct atcgagcttg caaaggactt ctccgatcaa aaatctgccc
    20941 gttttatcaa tggactgctc agccagtttg taacagaaga acaataaaaa gaaaaagtgt
    21001 ttgatagata tcaaacactt tttctttgcc tcccactatc taaaaaaatg ataatagata
    21061 taattgtaaa caaaaatcca gataggtttt gcatgattga gaaagttaaa aaaactatgg
    21121 cagagaatcg ttaatctcag attgtcggta gaacgataaa caagggcaaa aaagaaacca
    21181 atcagactat aatataataa actaattgga tctctgtgag atagtatcaa atggctaatc
    21241 ccaaagataa ggcctgataa gatgacatct aaatagtact ttgacttagg aaagaaggta
    21301 ttcatcaaat accctctatc aagagtctcc tcaaaaacag gaccgatgat tacaagcagg
    21361 acaaaagata agatagtcga taaaaaggtt ggttgtccat ttgaaagaac cacggtaaaa
    21421 tactcatcat gaatattcct atggttaatc aaatgagcat agcgtgccta aaaattaccg
    21481 agaatctgat aaaccacata cgttgcaaat aagtagaaga caaatgacca gttccagctc
    21541 tttttttcaa agataaagag catctttttc ttttttaacc tccaaatcaa tagaaggaaa
    21601 cttcccacta ataccattgt taaaataaga gaatagacat cagctcctaa ccctaaaatg
    21661 atcgtcacat acaatccaat tgtttgtggt aaataggtag atagtaaaat aataagcaaa
    21721 aatattccaa attgtcttag tttttttgtg tttctcatcg tacttttttg aaagattacc
    21781 ctgctcggaa gccgtacttc caagcatcta tataagaatt aagtgcccct tgcctcatat
    21841 agggagcaaa ttctctataa tataaccatc tactatatcc atcttcccaa acagcaagac
    21901 cacctgaagt ttgctccaag tcctcagttg aaagaactgt aaatgtattt gtacctgtca
    21961 ttgcaagtac cttcttaaaa tagattgttg taggctcaca tttatagtat atttcttttt
    22021 ttgtctattt tatagtctat ctcctcaact gtcaattttt caacctgaat tgcatttttc
    22081 cataaaaaat gagacctttc tagtctcatt tagtcattct tagtattttc taaatcgttg
    22141 atagcgttct tccagcaact cttctagcgg tttttgtgaa agtctagcca gctccgtttg
    22201 gagttctttt ttgacactct taatcagttc tttactagaa agtcctactt cagaaatcac
    22261 cttatccacc acgtccattt ctaacagttc atgcgaagtg attttcatca gttctgctgc
    22321 ttccatggcg cgagtaccgt ccttccataa aatggaagca aagccttctg gactgagaat
    22381 ggcatagata gaattttcca gcatccagac acggtccgcg acagctagag ccagagcccc
    22441 gcctgaacca ccttcaccga taataatggc gataatagga actttcaggt cactcatttc
    22501 catgagattg cgagcgatag cttccccttg accacgttct tctgctccga caccaggata
    22561 agcacctgct gtattaataa aggtcacaac tggacggcca aatttctcag cctgtttcat
    22621 caaccgcagt gcctttcggt agccttctgg atgtggttgg ccaaaattcc gtttgaggtt
    22681 gtcttgcaaa ctcttgcctt tttggatacc aacaactgtt acagcttggt ctccaagcca
    22741 accaatacca ccaacaactg caccatcatc acgaaaagaa cggtcaccat gtaattggat
    22801 aaattcatca aaaatgcctg tcgcaaagtc caaggttgtc aagcgactct gctcacgcgc
    22861 ttctctgact atttttgcaa tattcatcta ggactccctc catgcaatct gactaggcta
    22921 gcaatcgtat ctggtaagtc tcttcttttg acaatagcat ccacaaagcc atgttctaat
    22981 aggaattctg ccttttggaa atcctcaggc aagctttcac gaaccgtatt ttcaatcaca
    23041 cgacgcccag caaaaccaac caagctctgt ggttcagcca gaatgatatc gccttccata
    23101 gcgaaagaag ctgtcacacc accagtcgtt ggatctgtca aaatggtcag gtaaaagaga
    23161 ccagcatttg aatggcgttt aaccgccgca gagatcttag ccatctgcat gagactcatg
    23221 attccttcct gcatacgggc tccaccagag gctgtgaata ggacaactgg caatttttcg
    23281 acagtcgcat actcaaacaa acgagtgatt ttttcaccta caaccgtacc catagaagcc
    23341 atgataaagt tagaatccat aatcccaaga gccacagtct gacctttaat aagagcagtt
    23401 cctgtcacaa cggcttcatg cagacctgtt ttttcacgca tagatgccag tttcttttgg
    23461 taaccaggga aatgcaaggg atccttgctt tcaatccctg taaacaattc tttgaaggtt
    23521 cccatatcaa tcgtcaaagc caagcgttct tgggcagaaa tacgaaaggt atagctacag
    23581 tgcggacaga tacgttcact tcccagatcc ttctgataga tggtatgctt acagcctgga
    23641 cactgggaaa ataattcatc tggaacctct ggcttagctt gaggtttttc cctaaccgaa
    23701 cgattgggat tgattcgaat atacttatct tttttactaa atagagccat tgattcccct
    23761 tttcggttta aactcttaaa gtcattttat tctttttctt gatatttagg taagaaggtt
    23821 tccatcaaga aggaagtatc ataatcccca gcaatgacat tgcgatctga aatgaggtca
    23881 agctggaaat ctgcattggt ctgcactcct tcaatctcta attcatagag ggcacgttgc
    23941 attttcatca aggcgtcaaa acgattttcg ccgtgtacta tgattttggc aatcatacta
    24001 tcataataag gcggaatggt ataacctgga taaactgctg aatccacgcg caagccaact
    24061 ccaccacttg gcagatagag attagtaatc ttacctggac ttggagcaaa gttaaaggct
    24121 gggttttctg cattgatacg acactcgatg gcatgaccac gtaggacaat atcttcttgc
    24181 ttaacagaca aaggctgacc tgccgcaatg caaatctgtt ccttaacgat atcaacacct
    24241 gaaacaaact ctgttactgg atgttctacc tgaacacgag tattcatctc catgaaatag
    24301 aaattgctac ttgcttcatc aagaagaaat tcaatggttc ctgcattctc atagccaaca
    24361 aactctgccg ctcgaacagc agcagcacct atttcatgac gcagcgtttt tccgattgca
    24421 atcgagggac tttcttccaa aaccttttgg ttattccttt gaagagaaca atcccgttca
    24481 cccaagtgaa tcacatgtcc atgctcatca cctaggattt gaacctcaat gtgccgagct
    24541 ggatagataa cccgttctat gtacatggca ccattgccat aattggcctt ggcctcacta
    24601 gaggcagttt caaaggcaga aacgaggtca tctggttttt caaccttacg aatcccttta
    24661 ccacctccac ctgctgaagc cttgagcata acaggatagc caattttttc agcaacaatc
    24721 aaagcttctt cagagttatg cacttctcca tctgaacctg gtataacagg cacacctgct
    24781 ttaatcatct gagcacgcgc attgatctta tcccccatca tatccataac atgaccagat
    24841 ggaccgataa acttgatacc tacttcttca cacatggtcg caaatttgga attttcactg
    24901 agaaatccaa aaccagggtg aatagcttct gcctcagtca agactgcagc tgatagaact
    24961 gcattaatat tgagataaga ctctgttgcc ttgccaggac caatacaaac tgcttcatct
    25021 gccaaaagcg tatgaagagc ttccttatca gcagttgaat aaaccgctac cgtcgcaatc
    25081 cccaattcac gtgccgcacg gataatacga accgcaattt caccacgatt ggcaattaaa
    25141 atttttcgaa acatggagaa cctccttagt tcccaattgc aaaagtaagg ataccactgg
    25201 ctgcaagctt gccatccact tcagcctttg cttcaaccac agctatggtg ccacgacgtt
    25261 ttacaaaagt cgctgtcata accaattggt cgcctggtac aacttgcttc ttgaacttaa
    25321 ccttgtccat accagcgtaa aagaccagtt ttcctttatt ttcaggtttt gataactcca
    25381 acacaccagc agtttgcgcc aaggcttcca taatcagaac acctggcata actgggtatt
    25441 gaggaaagtg gccgttaaag aaaggttcgt taatggtcac atttttgata gcaacaatgg
    25501 tatcctcgct cacttccaag acacggtcca ctagaagcat aggataacgg tggggaagag
    25561 cttctttgat tccttgaata tcgatcattt gatacgtacc aatcctttac caaactcaac
    25621 catttcttcg ttagagacga gaatttccgt taccacacca tccttaggag ctgggatttc
    25681 attcatgact ttcatggctt cgataattac caatgtttga ccttttttga cactatcacc
    25741 aactgtaacg aaggcaggtt tatctggtcc agcagccaag taaaccactc caacaagtgg
    25801 actctctaca agatttccct cactagccac acttgcttca gctggagctg gaacttcttc
    25861 tgctacagtc tctgctggag cagatgtagg agctactgga ctcggtgttg ctagaacggg
    25921 tgctggagcg acttgagttg caacttcagg cacaggtctt gcttcattct tgctaaactg
    25981 caactcatcc gtcccatttt tataagaaaa ttctctcaaa cttgactggt caaattgagt
    26041 catcaagtct ttaatatcgt ttaaattcat acttatctat tctcccaacg tttgaaagca
    26101 agaactgcat tgtggcctcc aaaaccaaaa gtatttgaaa tagcgtatgg aatttctttc
    26161 tccaagcctt gtccataaac gacattagct tcgatataat ctgatacttc acttgtccca
    26221 gctgtcattg gtacaaagtt atgacgcata gcttcgatgg tgacgatagc ttctactgca
    26281 cccgcagccc ccagtaaatg tcctgtaaaa gacttggttg atgatacagg tacttcctta
    26341 ccaagaacag ctacgatagc tccactttct cctttttcat tggcaggagt tgacgttccg
    26401 tgagcattga cataggctac ttgctctgga gaaatctcag cttcttccaa ggctagtttg
    26461 atggccttga tagctccctg accttctgga tgtggagaag tcatgtggta ggcatcacaa
    26521 gtatttccgt aaccaaccac ttcagccagg atagtagctc cacgtttttc agcgtgttca
    26581 aggctttcta gaaccaacat ccctgaacct tcacccataa caaacccatt gcgatcctta
    26641 tcaaatggga tcgaagcacg agttggatcc tctgtagtag agagagctgt taaggcttgg
    26701 aaaccagcga tggcaaaagg tgtgatagaa gcttctgttc ctcccaccaa catcacatct
    26761 tggaaaccaa acttaatgga gcggaaggca tccccaatcg catcatttga tgaagagcag
    26821 gcagtattga tagatttaca aacaccgttt gcaccaaaac gcatggctac attcccagaa
    26881 gccatatttg gtaaagcttt tggaagagtc attggtttga cacgtttggg tcctttttca
    26941 tgaaggcgaa gtacctgatc ttcaatttcc ttgattccac caataccaga tgcaacgata
    27001 acaccaaaac gatccctatt aagagcctct acatcaagat tggcatgatt tacagcctct
    27061 tgggctgcat acaaggcata taaagaatag ttatcaaaac ggttggtatc tttttttaca
    27121 aagtatttat cgaacggaaa atcttggatt tctgccgcat tatgcacatc aaagtcacta
    27181 tgatcaaatt ttgtaatgcc accaatgccg attttcccag ttgctaaact attccaaaat
    27241 tcttctggtg tatttccgat tggagatgtt actccataac ctgttaccac tactcgattt
    27301 agtttcattc ttttcacctc tagctttcgc tacatactta agccaccatc aatggcaatc
    27361 acttgaccag ttagataatc ttggcctgct aaaaatactg tcaaatctgc aacctgctct
    27421 gcctgcccaa attctttcat cggaatctga gctagtgtag cttccttaat cttatctgat
    27481 aagatagctg tcatatcaga ctcaatcatt cctggagcaa tcacattgac tcgtatattc
    27541 cgactagcga cctcgcgtgc cacagacttg gtaaagccaa tcaagccagc cttagaagca
    27601 gcatagttag cttgaccaat attccccatc aaaccaacaa cactagacat attaatgata
    27661 gcaccttctc tggctttcat catcggtttc aagactgatt gtgtcatatt aaaggcacca
    27721 gtcagattga ccttgagcac tttttcaaaa tctgcttctg tcatcttgag cataagagta
    27781 tcttgggtaa tccctgcatt gttgaccaaa acatctactg aacccagttc tgcaatagct
    27841 tgatcaatca tacgcttagc gtctgcaaaa tctgatacat ctcctgaaat gggaaccacc
    27901 ttgataccat agtttgaaaa ctcagcgagc aattcttctg agattgcccc acgactgttt
    27961 aagacaatgt tggctcctgc ttgagcaaac ttgtgggcga tggcaagacc aattccacga
    28021 ctcgaacctg taataaagat atttttatgt tctagtttca tttttttcct ttcaaaactt
    28081 ctacttattt tagtctattt ttctaaaagt gctactaaac tcgcttgatc ttccacatga
    28141 gctaagtgag cagtttgatc aattttttta acaaaacctg acaagacttt ccccggtcca
    28201 atctcgataa agttgcttat gcctgcttct tgcatgaccc caatactttc atagaaacga
    28261 acgggttcct tgacctgacg cgtcaagagc tgagcaatgt cctctttttg catcacagca
    28321 gcttctgtat tgccgactag gggacaagta aaatctgaaa aacttacctg agctagagtt
    28381 tcagctagtt tctggctagc tggctcaagg agagcggtgt gaaagggacc tgacacctta
    28441 agaggaatca agcgtttggc acctgcttct tgcaaaagtt caaccgctcg atcaactgca
    28501 accacttctc cagcaatgac gatttgtgca ggtgtgttat agttggctgg agtaaccact
    28561 ccaagttcag aagctttttg acaggcttct tcaatgacct ctactggcgt attgagaact
    28621 gctaccatct tgccagagtc agcaggagcc gcttcttcca tataggctcc acgcttagct
    28681 accaaggcaa ccgcatcttc aaaatccaag gcgccgcttg ccaccaaggc agagtattct
    28741 ccaagagaca aaccagcaac catatcaggc tgatagccct tttcttgcaa taaacggtag
    28801 atagcaaccg aagtcgctag aatggctggt tgcgtatagc gggtctgatt gagtttgtct
    28861 tcttccgtat cgatgagata acgcaaatca taacctagca cctgactcgc tcgatcaatc
    28921 gtttctttaa caatcggata ctgatcatag aaatcccgtc ccatccctag atactgggca
    28981 ccttgaccag caaataaaaa ggctgtttta gtcatttctt acaactcctg cccagcgaga
    29041 ggcttcttct tgaattttct tagcggctcc gtaatacaaa tcttttagga tttcttcagc
    29101 tgtttcttct ttagaaacaa gccctgcgat ttgacctgcc atgacagagc caccatccac
    29161 atcaccgtga acaactgctt tggctagggc acctgctccc atttgttcaa agatttctaa
    29221 atcaggatct tcctgcttaa aggcatcttt ttcagccagt tcaaaatctc tagtcaactg
    29281 atttttaata gcacgaacag catgaccaaa gtgctgagct gaaatcgtag tatcaatatc
    29341 ccttgctttt aaaattttct ccttgtagtt tggatgggca ttcgactctt ttgcaactac
    29401 aaaccgtgtc cccacctgta cagcctctgc acctagcata aagccagccg cagcaccttc
    29461 accatccgca attcctcctg cagcaataac aggaatagat atagctgtgg ctacctgtcg
    29521 caccaaggtc atggttgtta atttaccgat atgcccccca gcttccattc cttctgcaat
    29581 aacagcgtct gcaccgattt tttccatgcg tttagctaaa gcgacactag gaacaacagg
    29641 aataacgatt atcccagctt catggaaacg ttccatatac ttgcttggat ttcctgctcc
    29701 tgttgtgaca actttaacac cttcttcaat aacgagatcc acgatatctt ccacaaaggg
    29761 agataagagc atgatgttga ccccaaaggg tttatcagtc aatgatttga ttttatcaat
    29821 attggccttg acaacttctt tcggggcatt tcccccaccg ataattccta atcctccagc
    29881 cttggaaaca gcccctgcca aatcaccatc agcaacccag gccatccctc cttggaaaat
    29941 aggatagtca atcttcaata attctgtaat acgcgttttc atagtgcctc caaccttcct
    30001 tgcttacgta atagttcgat ttcaccataa tttgacagtc aaactattac ctaaacaaga
    30061 gggagtgggt ttctccctac tccttctact aatattctgc ttattttgct tgctcttcaa
    30121 cgtaagcaac caagtcacca actgttttca agtcattttc tgcttcgatt tggatatcaa
    30181 aagcatcttc gatttctgag attacttgga acaagtccaa tgaatctgcg tccaaatcat
    30241 caaaagttga ttcaagtgtt acttctgatg cgtcttttcc aagttcttca acgataattt
    30301 cttgtacttt ttcaaatact gccatgatag gactccttta aaataaatag tttttttata
    30361 acaatgtgtt caccacatga ttacctaaat tgtaagaatg agcgtgcccc aggtcaagcc
    30421 tccaccgaag cctgatagaa gaacagtctg gctaccatct aaagggatga gaccttgttc
    30481 tacacactct gaaagtaaaa tcgggatact ggctgcactg gtattgccat attccatcat
    30541 attggctgga agtttggctc ggtcaacacc aatttttcta gccatcttat ccaaaatacg
    30601 gtcattggct tgatgaagta gcagataatc caagtctgtc acctctatag gagattcatc
    30661 aatagtctgc ttgatagact tggctacatc tcgaatggca aaatcaaaga ctgtgcgtcc
    30721 atccatcttc aaaaacgaat ctgcactttc ttgatctgaa aatggagaat gcaaacctga
    30781 atgcccataa gttaaacact cgctgcgact tccatcgcta ttgagactct cagctaagaa
    30841 atgctcttgc tcgctagctt ctaacaagac accaccagca ccatctccaa acaacacagc
    30901 tgttgatcga tccgaccaat cgactgcctt agagagggtt tcactaccaa tcaccaagcc
    30961 tttttgaaag cgaccagaag cgataaactt ttcagcagtt gaaagagcaa atacaaatcc
    31021 actgcaagcc gcggttaagt caaaagcaaa ggctttatta gcgccaatat tagcttgaac
    31081 acgagcagct gtagagggca tcatcgaatc tggagtaatg gtagctagga tgataaaatc
    31141 cagttctttt cctgttattc cagcttttgc catcagtttc ttagcaacct ctgtagccaa
    31201 atcactggta gattctgttc ttgaaatatg cctttgtcgt attcccgttc gacttgaaat
    31261 ccactcatca ttggtatcca taatctgagc caagtcgtga tttgtaacca cttgctctgg
    31321 cacataatga gcaacctgac ttatttttgc aaaagccatt atttcaaatc ctccaaaaat
    31381 tggtaaagat tagtcaaacc tttacccatg acagcaattt cttcctcgct catgccatca
    31441 ataatttttt ctaccatggc cttgtggaag cgtttatgca gcctatgaat caagcgaccc
    31501 ttctttgtca aatgcagatg caccacacga cgatcctgtt ctgaccgaac tcgctcaatg
    31561 tagcccttac gctctaaatt gttcaaactt gtcgtaacag ttccaagagt taccatcaac
    31621 tcttttgaca cttgacttgg agtcacgtct ggagccttac cgatgacatc aatcgtatgc
    31681 atttctttga tggagatatc cttaaaacga ctacctctca agttcacttc ctcaattaca
    31741 aggacattgt taaatataga tgttaaatat tcattgattc gttggtagtc catttttcat
    31801 atccctcctt cttcaaaaaa cttttacaat caaaacattt gacagaaaga attatatcaa
    31861 aattcaaaga atgatgcaag tattttttat tttcctgtaa atttaggtct tcttctctcc
    31921 gaatgagctc gcactccttc tttgaaatcc tctgtttgag ctaaggattt ctgtaggttc
    31981 agttctaaag tagcgtaacc ctgccagtct ttaaattggc tctcccaaac caacttctta
    32041 atggcagcat aggaattact tgaagcacgt cttaattttt taagaagctg ttctctcgtc
    32101 ttttcaagtt tttcagcttc agaaacgcga taaaccaacc cccattctag ggctttttct
    32161 gccgttaaag cctctcctgt catagctaat tgagcagcac gcgtcacacc gatactgcgg
    32221 ctcaagagat gaattccccc tgcatctgga gccaaaccaa caccaacaaa ggcttggata
    32281 aacttagcct tatccgtcgc caaacagaaa tctgccgcaa cagccatatt cgctgcggca
    32341 cctgcaacag caccgtcaac ttccattaaa acaggtttgg ctatttgctt gattttataa
    32401 gaaatcgtat tgaccaactc tgcgattttt gtcaatgatg gaatatcatc ctcatccact
    32461 gcccgcttca tctctaccaa atctccccca actgagaaga cctttccatt ggcattgatt
    32521 aagataaaat gcacagctgg attttcttct gccaaagtca gagcttctaa aatctcctca
    32581 cacatgggaa tatgaaaacc atttgcgacc tcaggacggt tcaaggtaag gattgccaag
    32641 tcctcttcaa gctgataaat aatgtgttcc atcagggctc ctttttattt tataagcagt
    32701 ttatactctt cgaaaatctc ttcaaaccgc gtcagcttcc atctgcaacc tcaaagcagt
    32761 gctttgagct gacttcggct agcttcctag tttgctcttt gattttcatt gagtgttaaa
    32821 ttatttcact gtcaaagtat atctttttta ggagcagaaa gcaagaaaaa atcgactgaa
    32881 agtgtctcag ccgataagaa aggctcgctt taggctagaa agcatcttat tttcttcatt
    32941 gaaaaaagcc tttctttctg ctataatcgt ataaaatact tactttagga gttcttatga
    33001 aagttgttaa atttggaggt agttctcttg cctctgctag tcaattagaa aaagttttaa
    33061 acatcgtcaa aagcgattca gagcgtcgtt ttgtagtcgt ttctgcgcct ggtaaacgca
    33121 atgctgaaga tactaaggtt acggatgccc tgattaaata ctaccgcgac tatgttgcgg
    33181 gtaacgatat tagcaagagc caaagctgga ttatcgaccg ctatgctgct atggttagtg
    33241 aattgggact aaaaccagct gtgctagaaa aaatttctaa aagtattcac gccttggcca
    33301 ctcttcctat tgaagaaaat gaatttctct acgatacttt cctagcagcc ggtgaaaata
    33361 acaatgccaa attgattgct gcctacttta accaaaatgg tatcgatgca cgctatatgc
    33421 accctagaga agctgggatt gtggtcacaa gtgaacctgg tcacgctcgc atcattccat
    33481 caagttatga caagattgaa gaattgacaa acaccaatga agtccttgtc attcctggtt
    33541 tctttggtgt cactaaggaa aatcaaatct gtactttctc acgtggaggt tctgatatta
    33601 caggttctat cattgctgct ggtgtcaaag ctgacctcta tgaaaacttt acggacgttg
    33661 atggtatctt tgcagcccac cctggtatta tccaccaacc acactcgatt cctgagttga
    33721 cctaccgtga aatgcgcgag ttggcctatg caggcttctc agtccttcat gacgaggctc
    33781 ttcttcctgc ctaccgtgga aaaattcctc tggttatcaa gaataccaac aaccctgacc
    33841 atccaggtac tcgtatcgtt ctaaaacaca gtaatgatga atttccagtt gtgggaattg
    33901 ctggtgactc aggctttgtc agcattaaca tgtcgaaata cctcatgaac cgtgaggttg
    33961 gatttggccg caaggttctg caaatcctgg aagaacttaa catcggttgg gaacatatgc
    34021 caacaggtat cgacgatctt tctatcattc tccgttctcg ccaactaact cccatcaagg
    34081 aagaagaaat cctgcgtcag ttggttcaaa aggctaaagt agatcatgca gaaatcgaac
    34141 acgacctttc tatcattatg attgttggtg aaaaaatgaa gagccacatc ggagtgactg
    34201 ctactgcgac acgcgctcta tctgaaaaca aaatcaacat ccagatgatg tctcaaggtt
    34261 ctagtgaagt ttctattatg tttgttgtca ataaagacca agagaaagca gcaattaaag
    34321 ccctctacaa tgcctttttt ggagaaagta aggaagacta agcatggccc aatcacttaa
    34381 caaaacagta ctcctcagta cgacaggcac ttcctacctc tctatcgctg ggaaagttgg
    34441 gaaattcctt gtcggagatc aggctttgga attttaccca gatgtcaatg tcgaacaatt
    34501 tatccagatt ccttggagcc atatcaatca gattggagcc aatgtcactg gacgcaaaat
    34561 cagccgccac ttcgaagtct ttacagacaa aggaaaattc ctctttgctt caaaagactc
    34621 aggtgccatt ctcaaaattg cacgcaaaaa actaggcaat gacaaggtcg tcaaacttcc
    34681 gaccctgatt cagacaatta gccaaaaatt taaaaatcta tttgcaaaaa agtagaaact
    34741 ttagtataat catagcaacg gataagtagg ttatcttctt ctttcagaaa gtctgcgggt
    34801 actgcgagca gataggaggg ataggtgaaa ttctaccgtt aataacaatt acatacacaa
    34861 tcaagtgcac acctgtgaag ttggatggaa ccgtggccct gccactccaa cgttttgtca
    34921 ggcgtgcttt tttcataaag gagttcttat gttagatatc aaacgtattc gtacagattt
    34981 tgaagctgtc gcagaaaaat tagctacacg tggtgtagat gctgctgtct tgaatgaaat
    35041 gaaagaaatc gatgctaaac gtcgtaacat cttggtcaag gttgaaactc tcaaagcaga
    35101 acgtaacaca gtttctgctg agattgccca agctaagcgc aacaaggaaa atacagatga
    35161 caagattgct gccatgcaaa atctatctgc tgaggttaaa gccttggatg ctgaattggc
    35221 agaaatcgat gctaaattga cagaatttac aacgactctt ccaaatatcc cagctgacag
    35281 cgttcctgtt gggactgacg aagacgacaa tgtggaagtt cgccgttggg gtactccacg
    35341 cgagtttgac ttcgaaccta aagctcactg ggatctcggt gaagaccttg gtatccttga
    35401 ctgggaacgc ggtggtaagg taacaggcgc tcgcttcctc ttctataaag gcctcggtgc
    35461 tcgtttggaa cgtgctatct acaactttat gttggatgaa catggaaaag aaggctatac
    35521 tgaagtcatc acaccttaca tagtcaacca tgattctatg tttggtactg gtcagtatcc
    35581 aaaatttaag gaagatactt ttgaactcag cgataccaac tttgtcttga ttccaactgc
    35641 tgaagttcct ctgacaaact actaccgtga tgaaatctta gacggcaaag atcttccaat
    35701 ctacttcact gctatgagtc cgtcattccg ttctgaggct ggttctgccg gtcgtgatac
    35761 gcgtggcttg atccgtttgc accaattcca caaggttgaa atggtcaaat ttgccaaacc
    35821 agaagaatct tacgaagaat tggaaaaaat gacagccaac gctgaaaaca ttcttcaaaa
    35881 actcaacctt ccataccgtg tcgttgctct ctctactgga gatatgggct tctcagctac
    35941 gaagacttac gacttggaag tgtggattcc agcacaaaac aattaccgtg aaatctcaag
    36001 ctgttcaaac acagaagatt tccaagcccg tcgtgcccaa atccgttacc gtgatgaagc
    36061 agatggcaag gtgaaactcc ttcatacctt gaacggttct ggacttgcag ttggacgtac
    36121 agtggctgca attcttgaaa attaccaaaa tgaagatggt tctgtgacca tcccagaagc
    36181 acttcgtcca tacatgggtg gagctgaagt catcaaacca taaaaaataa ggtttagcta
    36241 tttctagcta gacctttttc gtaaccaaat cagataagca cctagtacaa agaataaaat
    36301 agttaggcat ataatggttt cagccaatac caggtaatcc agaaatggaa gtttcaaaat
    36361 tccctgagcc atcttgagcg aggtcgctgt gataatggtt gggaaggtga gggctgagaa
    36421 ggctggttga aaaccttgtt ttaaaatgtt gggcagacga gttaaaacaa agaaaaagaa
    36481 ggattgagaa gccaaaatca tgacaatcaa gacccaagtc ggcaggctgg ttcctcctac
    36541 tcgaactaga gaagccaaga gtagagagaa aggagcacag tagattcctt cttgtccaag
    36601 caaggctagt gggagtggat gtttctttaa atcgctataa ataaggggat agagatagaa
    36661 ggtcaagaga aaaccaaaac tcaaggtcgc ataggcaatt tcgataatac ctaccagagg
    36721 ataggtcaag gcagccactg ctatccccac atagagaacc gtccaacttg gagtggcatg
    36781 aaccctccgc cctggacaag caaacttgat ggtaaaacca gcaatcaagg tcaaatccaa
    36841 gagaaatgaa aaccaccaaa tcccttgtgc taccaaagga agataagaga atacgcgaaa
    36901 gacataggtc gataaaatca tcccagccat aggaaaggtt gccattcctg acaaaagagg
    36961 gggcttggtc aattcttgct tggtttcttt ccaattaaag agatgcagaa ttagaaagta
    37021 aatccataaa accaaaccag tcagactaaa aagatgggat agaaccggca acgtatctaa
    37081 aataagattt ccagctcctg ccaaacctag caaacaacct gaaaatacta aggggagttt
    37141 tttcatccta acctccaata atcatgttag tttcagtata acataaaagc gcttaaatga
    37201 ggatttaaaa aaacgaagtc cgcttatttc agacttcatt ttactcagat atgaattagg
    37261 cataaggttg caattctgga ttaattggtg tattagctaa gttgttggca tagttacaga
    37321 ggattgctag gctgacacca aaaaccacat ccaaggcatt ttgttgagtg tagccagctt
    37381 ctaaaaactc agacaaggct tcatctccta cacgaccctt ggtattgata actgccaagg
    37441 taaacttagc tagggtatcc aatttaggat ctgtttcaat tggagtacga ttgcgaagag
    37501 cttgaatcaa gtcatcattc atctggattt gttttatgga aaaggctgtg tgacctgcga
    37561 cacagaaggc acaaccattg gtcacggctg ccgtgatttg caccacttca cgctcaacgg
    37621 gtgtcaggct gttgcgacgg tggatagatg agacaatttg gtaggcttct aaaacagtcg
    37681 gggcattggc caagagaccg attaggttgg gaatatagcc attgttgtct ttttctactg
    37741 tttcaagaat ttctttcact tctgctggtg ctgactctac tgtatggata gtaaatgttg
    37801 tcataagata cctcttttct tattattgac actaatatta ttggaaaatc ttataaaatc
    37861 ctgattccta agtttatcta agataaagct ttattctctc ataagatttt cgttgttata
    37921 ttagtttatc acacttccaa tcacttgcat aatatatact atatatcagg ctgataaaaa
    37981 ttatttatag gcaaaaaaat cacacgagct gtgtgattcc attatttgtc aaaatacttt
    38041 ttagtttcag caataacgac tggcgacaag accaagaggg caatcaagtt tggcagagcc
    38101 atcaaggcgt taacgatatc tgcgataatc cagaccatat ccaactcgat aaatcctcct
    38161 aacaagacca tgagcacaaa aaccacacgg tagagccaga taaagcgagc cccaaagagg
    38221 aactcaaaac agcgttctcc gtaatagttc caacctagaa tcgttgtaaa ggcaaaaagt
    38281 acaaggaaga tggtcaagag ggcaggccca aagtgtgaaa agactgttga gaaagctgac
    38341 tgagtcaagg caaccccatt caagtcacca ctccaaactc cagttaccaa gatggtcaaa
    38401 ccagttagag tacaaatgat gagggtatca ataaaggttc ctgtcatgga aatcaaacct
    38461 tgctctactg gttcatttgt cttggcagct gcagctgcaa taggagcaga acccagacca
    38521 gattcgtttg agaacacacc acgcgccaca ccattttgaa tagccatccg aacgctagca
    38581 ccagcaaatc cacctaccgc agcaagggga ctaaaagctg aggtaaagac taaagcgatt
    38641 gtgccaggga tttttccgat attaaagaaa ataactgtaa gagttcctaa gatataaatg
    38701 agggccataa aaggaacaac agtagttgaa accttagaaa tagacttgag tccaccaaag
    38761 actgcaatcg ctacaaagac agacaagacg agagctgtga tggctggcga aatcgtcgtt
    38821 gtattttgga tagattctgt aatcgagttg acttgggtga aggttccgat tcccaagaga
    38881 gcaaccaata ctcctgctac tgcaaacaaa acagcaagtg gtcgccactt ttctcccatc
    38941 cctagaagga tatagtgcat gggacctccc gctactgcac catggtcgtc cttggtgcgg
    39001 tatttgatgg ccaagagtcc ttccgcatac ttggtagcca ttccaaagaa agccgccatc
    39061 cacatccaaa atagagctcc tggtccacca accttgatag ccgtcgcaac tcctatgata
    39121 tttcctgttc caacagttga tgccaaggct gtacacagag ctgcaaaact ggatacatca
    39181 ccatgtccct tatcctggat aaaaataagc tgaaaggcct tgggcagacg caaaacctgc
    39241 aagagtccta gccgcatggt taggtaaatc cctgttccga ccaataaaat caagaggggc
    39301 ggtccccaag caaaagcatc gattgattta agcaattcta acatttcctt ctcctatcgt
    39361 ttcaacccca aaagaaagag cacatgcaag atacatgtac tctggaatgc ttagataaat
    39421 gctaaaaagc ggtctatcct agctctgtcc ttttacctga gagtttgagc agttgcctgc
    39481 cttgcccctt cggtgccttt acggtctctc cagagttccg tccatttaca gtcatggaaa
    39541 atcaaacgat tccccacttc tattaaactt cattcggtgt tggtatttaa ttgattctaa
    39601 ttttacaaaa aatgttggct tttgtcaatg tgtttattag taaaaattag ttcaacagtt
    39661 tttactttat aaagtccaga atactgctat cctttaaaag tgacaatagt cgcaccactg
    39721 cctccagcat tttgtggggc atagccgaaa ctcttgacat gtttgtttct ttgcaagtat
    39781 ttggtaactc cttcacggat gactcctgtt ccgataccat ggatgatatc aacttgagcc
    39841 atattgttaa gcaaggcttg gtcgatgaag gtatctagct cattcatggc ttcttcatag
    39901 cgcttgcctc gaagatccag tctagcttga ggtcctcgcc cagaagttcg tttcacaaca
    39961 ttgacctgtt tcttcttgac tggtttttct tgctgggctt gaacaagatc aaactctttc
    40021 tcttccaagg tcatcttaat caagccaact tgggcttccc agcgaccgtc cttgagttga
    40081 ctggtcaagg taccacgctg accataactg agaaccacga tatcatctcc cacctttgga
    40141 gctcgttttt tcttggcctt ttgaaggacc ttatttttag acaagtccac tttttcagga
    40201 gccaattttt tcaacttggc cttggcttca atgatttcgt ggggcttgag ttgggattta
    40261 ctgtggagat ttttgagaat ctggtcactt tcacttaggg ccatatccac aatctcagca
    40321 gcctgttcac gcgccttgtt aagctcggtt tccttttcac gattaagctc gttgtagagt
    40381 ttttttagcg cacggttcat cttgagattt tcttgctcca cctcacggat attgtccaaa
    40441 cgtttgcggc tttccagcgt ctgctcttct aattgctcaa tgatacgatt gacgtcattg
    40501 tcctgatcga tctgctgact ggcatctcct acgataactt cagataggcc tagacgtttg
    40561 gcaatttcaa aggcattact tcggccagga acaccctgca taaagcgata ggtcgggcga
    40621 agagttgcag tatcaaactc catactggca ttttgcacaa aggctgtctc aataccgtag
    40681 gccttgagtt ctggatagtg ggtcgtcgcc atggtcttga tttgacgcag gcgaaggtcc
    40741 tccagaatag ccatggcaag ggctgctccc tcttggggat cagtaccagc ccccaactca
    40801 tccaaaagta agagtgaatg ttggttgacc ttgccaagaa tatccacgat attggtcata
    40861 tggctagaga aggtagacaa gctctgctca atagactgct catctccaat atcagcaaag
    40921 atttcttcaa aaataccaac acgacttccc ttgtctgcta aaatcggcaa tcctgactgg
    40981 gccatgacct gtgtcaagcc cagagttttg agcatgatgg tcttcccacc tgtattggga
    41041 cctgtaatga caatagctgt taaatcttga ccaaaatgga catcatttgc gacggcattt
    41101 ttgaccaaag gatggcagac atggagcagt tgaatctctt gattttctga cagctgaggc
    41161 acgactgctt gtctttcttg gataaatcga accttggcac gaatcaagtc cagatgaccg
    41221 ataatccaag cgtcattagc aatctcagcc gcatgagggc ggacacgctc agaaatttct
    41281 tggagaatgc gaagcatttc atagcgctca tctgctcgca gactagcaat ttcttcgctc
    41341 agtttgacta cctcacgtgg ttcgatatag acggtgtttc cactagcaga aatatcatga
    41401 acgacacctg caatcttatt gcggtaggtg tttttgactg gtaaaacctg acggccattt
    41461 ctgctagcaa caattccttc cgtcaacatc tgcgcttttt gcttgagcaa gtcttgtaaa
    41521 acatcgcgta cctgactctc gctatcatgt atttttcgac ggattcgcgc caattcttca
    41581 ctggcaaaat tttcaatgaa acccgcatca ttaaaggcct gaagatttcc ttgtaattgc
    41641 ggaaaatcat gtaatttctc aaaccaaagg gctaattctt ccaagctgac attttccaga
    41701 ttggtgtaaa aattttgaag ttctcggctg gcaagaagca cgcgtttcaa gagtaggaac
    41761 tcctcgatat tgagatccgc tcccatctcc aacctcttgc agactcctgc aatttcctta
    41821 gttgagagaa tagtaaaatg cggttgctcg acgaaaagag cctgcatttc cttcatctca
    41881 gcaaaagcct gtttgatttt atctgctttg gcagtcggag ccagttgtct caattgctcc
    41941 aagccctgct cggtcaacaa atgaggctca aacaaggcct tgaccttatc gaactctaat
    42001 gtttctaata ttttcttatt catctttatt tccttgtctt tgaatgtcta ggtgtggtag
    42061 ctttttacat tctgatagat tcgagtcaaa tctgtaaaca aagggctagg aaaactcctg
    42121 ccctttttat ccgattaaat ttgtcaccca gatttgtttg agccaactgg ttgttatcgg
    42181 tatgctctgg atgatgtgtt ttgcgacgat actcttttca agaggatttt gtataactgc
    42241 catggggatg gtcgccaaga ttgtcaaggc catttgcaag acaaataagg tcaccaacat
    42301 ggacaagata cctgctgaaa cttggaacaa cttaccaccc agttttttgc taggaatcaa
    42361 gtgtaagaga agaccaagca aacgaccaat gctatagaca atcccaaata caagcaagta
    42421 gccgatacct gcataaaaga ccttatccag ctgaaagagt tgatccgatg ggaaaaagaa
    42481 agtcccctga ccttcctgcg aatttgcata agggagcaat aaatggaatt gctctccaag
    42541 ccccttataa aactggccag ccataaaagc cgatgccatg gctgaaatca ggtaataaac
    42601 ctgtaagagc aggcctctcc gatagccgat ataaaatccc caaaccaaga ccaatagaag
    42661 aaggaatgaa atcataagga atcctcaatc ttgctctgtt cttgcttaca agtcacaagc
    42721 ttgtgacgga gttcttctag ctcttgctcc ttatcgtcaa attcaatctc acggctgagc
    42781 tgagttgata aacagttgac tgccaacaaa agagcgattg tttcatcatc tgcgctaggc
    42841 atttgttctt taattgcttg gtatttttct gtcgcaacct tagcgatttc ctccataaaa
    42901 aggttatcat gttcgcttgt caaggttaac gattttttcc cgaatgtaaa tttgaatcga
    42961 tttagatttg ccataaaatt cacctcacga tattatacca aaattcgcta attttgtcag
    43021 tttttacaaa ttttactgct tttgtggtac aatagaaact atggcaagta tcacactcac
    43081 accaagcgaa aaggatattc aggcttttct tgaacactat caaaccagtc tggctcccag
    43141 taagaatccc tatatccgct actttttgaa actacctcaa gcaacggttt ctatctatac
    43201 ttctggaaaa atcttgcttc agggtgaagg ggctgagaaa tacgctagtt tctttggcta
    43261 tcaagctgta gagcaaacca gcggacaaaa tcttccttta attgggacag atgaggtggg
    43321 aaatggttcc tactttggtg ggcttgcagt tgtggctgcc tttgtcacat ctgaccagca
    43381 cgacttttta cgaaaactcg gtgtggggga ttctaagact ctgaccgacc aaaagatccg
    43441 tcagattgct cctattctca aggaaaaaat ccagcaccag gcactccttc tctcacccag
    43501 caagtacaac gaggtcatcg gagaccgcta caatgctgtt tcggttaagg ttgccctcca
    43561 taatcaggct atctatctcc tccttcaaaa aggtgttcag cctgagaaaa ttgtgattga
    43621 tgcctttacc agtgctaaaa attatgacaa gtacttggca caagaggcca atcgtttcag
    43681 caatcctatc agcttagaag aaaaggctga gggcaaatac ttgtctgtcg cagtttcttc
    43741 tgtcattgcg cgtgatctct ttctggaaaa tcttgaaaat ttgggacgag aactgggtta
    43801 tcagctccca agtggagctg gaacggcttc tgacaaggtg gctagccaga ttttgcaagc
    43861 ctatggtatg cagggactca gcttctgcgc caaattgcac tttaaaaaca ctgaaaaagc
    43921 gaaaaaacgc ttagaaaggt aagttatgaa ttcatttaaa aatttcttaa aagagtgggg
    43981 attgttcctc ctaattctgt cattactagc tttaagtcgt atcttttttt ggagcaatgt
    44041 tcgcgtagaa ggacattcca tggatccgac cctagcggat ggcgaaattc tcttcgttgt
    44101 aaaacacctt cctattgacc gttttgatat cgtggtggcc catgaggaag atggcaataa
    44161 ggacatcgtc aagcgcgtga ttggaatgcc tggcgacacc attcgttacg aaaatgataa
    44221 actctacatc aatgacaaag aaacggacga gccttatcta gcagactata tcaaacgctt
    44281 caaggatgac aaactccaaa gcacttactc aggcaagggc tttgaaggaa ataaaggaac
    44341 tttctttaga agtatcgctc aaaaagccca agccttcaca gttgatgtca actacaacac
    44401 caactttagc tttactgttc cagaaggaga ataccttctc ctcggagatg accgcttggt
    44461 ttcgagcgac agccgccacg taggtacctt caaagcaaaa gatatcacag gggaagctaa
    44521 attccgcttc tggccaatca cccgtatcgg aacattttaa gaaacctaag aggccgagaa
    44581 tcaccaatct cagcctcttc ttctatcgtg agaaaatgat tggtaactat ctaaacttac
    44641 cagaacagaa acacctcaac tctcacctat tcatgcaaag gaattttatg gaagtttatt
    44701 tttcaggaac cattgaacgg attatttttg aaaatcccag caatttttat cgcatcctcc
    44761 tcctagaaat cgacgatacg gacgcagagg attttgatga ttttgaaatc attgtcacag
    44821 gaaccatggc tgatgtaatt gagggcgaag actatacttt ttgggggcaa attgtccagc
    44881 actccaagta tggagaacaa ctgcaaatca gtcgttatga tcgcgcaaaa ccaactagta
    44941 agggcttggt caagtacttt tcaagtagcc atttcaaggg gattggtctc aagacagctc
    45001 agaaaatcgt ggatacctat ggcgaaaata ccattgacga aattttgcaa cacccagaaa
    45061 agttagaagg catcgcagga ctctctgcca aaaatcgcga ggctttcgtc tccactctcc
    45121 gtctcaacta cggaacggag atggttttgt ccaaactagc caactacggc attcccaaca
    45181 aactagcctt tcagattcaa gacttttaca aggaagaaac ccttgatgtg gttgaaaatt
    45241 atccctacca gctggttgag gatatcaagg gtttgggctt taccattgct gaccaactag
    45301 ctgaggaact aggcatcgaa agtcaggctc ctgaacgctt ccgcgccggt ctagttcaca
    45361 gtctttttca ggcctgtatg gaaacagggg acacctatgt tgaagcacgg gatttgctgg
    45421 aacaaaccct tactctcctt gagtcttccc gtcccgtgga actagacccc agccaagttg
    45481 cccaagagct ctcctacctg atcgaagaag acaaggttca gcagattgat accaagatct
    45541 ttgacaacag cctctttttc gctgaggaag gcatccgcag tcacttgatt cgtatccttg
    45601 aaaaaggaaa acagaagagt catgatttag aaaccattca aaaacatatc actactatcg
    45661 aggaagagct gggaattgag tatgataaca ttcaaaaaca ggctatctgt gatgctatcc
    45721 agaataaggt ctttatcctg acaggtggac ctggtactgg taagacaact gttatcaatg
    45781 ggatcatcgc tgtttacgcc ctgttagagg gacttgacct caggaagaaa agcaacctgc
    45841 ccattcttct tgctgctcca actggtcgag ctgctcgtcg catgaatgaa ttgacaggtt
    45901 tgcctagcgc gaccatacac cgccacttgg gaatgacagg tgacgatgat accagtcatc
    45961 tggaagatta cctagatgct gactttatca tcgtggatga attctctatg gtggatactt
    46021 ggctggccaa tcaactcttc tccaatatct cttctaacag taagatcctc atcgtaggtg
    46081 acagtgatca gctaccttct gtcagtcctg gacaggttct agcggatctg cttcatattc
    46141 ctttgattcc tcagactcgc ttggaaaaaa tttatcgaca aagcgaagaa tcaaccatcg
    46201 tcaccctagc tagtcagatt cgacagggca tcttgccagc tgatttcacc aaaaaaaaag
    46261 ctgaccgttc ctactttgaa attgctagtg gccatattcc tgccaccatt gaaaaaatct
    46321 taggtgccgc cctcagaaat ggtattcctg cccgtgatat ccaagttctg gctcctatgt
    46381 accgagggac ggcagggatt gatgctatca atcagctcat gcaagacctg ctcaatcccc
    46441 cacaaaaaga tcaactcagt tttgaagctc ctcagtgcca ctatcgtaag agagacaagg
    46501 tcattcattt ggttaacgat gctgaaatca atgtctttaa tggggattta ggagctatca
    46561 cagacctgat tcctggtaaa tacaccgaat cgaaacaaga cgagattgtc attgattttg
    46621 atggtaatga agtctcttac ccccgtaacg aatggtacaa aattcgcttg gcctatgcca
    46681 tgagtattca taagtctcag ggaagtgagt tcccagttgt catcctaccg attactagtg
    46741 ctagccgacg tatgctggag cgaaatctca tctacacagc cattacacgt gccaaaagca
    46801 aactcatctt actaggcgaa ttacaagcct tcgactatgc tacccaacac atcggaactg
    46861 cccgaaaaac ctatctgatt gaacgcttca gtgatctact ggagaatgtt gaagaaaagc
    46921 aacaagctgt ctctgaaaca gtcacatcaa gtgcctctga acaatcctac atcctaaccg
    46981 aagaaaactg ggaccgcatc ccagccatga ttgggattac agacacagac ctcaaagaga
    47041 tttttggaaa atagtgcatc agaaaaccca ccaattcagg tgggttttct gtttattaag
    47101 attattttac tgttgctgtg cttgtgatca attcaacagc ttttttgata gtgatatcat
    47161 gtttcaacat gtcagctgaa agcaagtttt gaacttgtgc aacttccatg ttgtagtctg
    47221 ctgccaattg ctcaacttct ttttggattt cttcttctga agcatcaaat ccttcagctt
    47281 tggcaactgc ttcgataaca aggttagtct tagtacgtga ctcagcttct gcttggtatt
    47341 ggttgtgaag gtcttcttga gtagttccag tgatttggaa gtacatgtca gggttgatcc
    47401 cttgacgttg caaattccca aggaattcat ttactgaacg gtgaacttct tcatggatca
    47461 tttcttctgg aagttctacg atttcagcat tttctacagc tgtatcaatt gctgcacctt
    47521 caactgcatc tttgtaagct tcttctttag cagcagccaa ttctttgcgg tatttttctt
    47581 tcaagtcagc aagtgtttca acttcttcat caatgtcttt tgcaagttca tcgtcaagag
    47641 ctggaacttc tttagctttt acttcgtgga tagttgtcac gaatttagct tctttacctg
    47701 caaggtcttc tgcttggtag tcttctggga atgttacgat aacatcaacg gtttcgccag
    47761 ctgagtgacc taccaattgg tcttcgaaac cagggatgaa ttgacctgaa ccaagtccaa
    47821 gtgagaagtt ttcacctttt ccgccgtcaa attcaacacc gtcgatagaa ccaacgaagt
    47881 cgatcacaac agtgtcgccg ttttcagcag cagcttcctt gataaccaat tcagccaggt
    47941 tgttgcgttc gcgttcgata cgctcttcaa catcagcgtc agttacttct ttttctacat
    48001 caactgatac ttcaaggttt ttgtagtcac ccaattttac ttcaggtttt gtaacgactt
    48061 cagcagcgat aacccagtct tgaccttttt ccattgaagt tacgtcaatt tttggttggg
    48121 caaccacttc aagaccagct tcttttacag ctgcttcata agcgtttggc aaaagagcgt
    48181 tcataacgtc ttggtaaagt gattcttcac caaatttttt atcgaagata ggacgtggaa
    48241 ggtgaccttt acggaaacct ggaacattaa gagatttctt cactgacttg aagacacggt
    48301 ccaattctgg tttgatttgg tcttgagaga tagtgaaagt caagacacca cggtttgttt
    48361 ctttgttttc aaatgataca gacattctgt catttctcct taaaattttt taaatacagt
    48421 ctattataac attttctata aataaaatct agactaatgc agccaattat agacaacaag
    48481 cctttttcct aactaaaaca ctcataaagt atagacaatt ttagactact ttggatatct
    48541 tttggttagt cattttccaa aactaattta tctaattttt cagttatatt tgacttcatc
    48601 ttctcagtaa catgagtata aacacttaaa atctttgttt cattagtata atctacacga
    48661 tccattatcg ctgttatagg tacttccaat tcagcaagca aacttatatg cgaatatcta
    48721 aaaacatgag cagtcaatac aaaatcatct ttcttaattt cacttttcct aaaactgttt
    48781 ttcaaaaagt aattgaaaca agttatcatt aagggagaac cattatttgt aaatatataa
    48841 tcaccttctt ctaaaagaag atattctttt aaaatttcta acactctatc actaatacca
    48901 attactctat atgaagctaa acttttcgga ctatccaaaa atacttcgtt attggacgat
    48961 tacattatag taaaacgaaa taagaacagg acaaatcgat caggacagtc aaatcaattt
    49021 ctaacaatgt tttagaagta gaggtgtact attatagttt caatctacta tacaagacaa
    49081 aattgaagaa atctttccat tataaaacgc atattatcaa ggtttttaaa cacctaataa
    49141 tatgcgtttt ttcctatttt aaagactttt atccacctat tatacaaagt taagtatcca
    49201 tcacagttta caattagcct tcattaccta acccattcac catccttcaa gagagtaacc
    49261 tttaagaacc gaataaataa atggcaaatt tcgttcattt aatttaactg cactgttaat
    49321 ttgattagct ccatctccta aagtatgcac tcctactaca cggtgactag catcataaac
    49381 tgtagatcca ctagacccct ctaaagtatc aacttggtaa tccaagaaca taccatcatc
    49441 acttaaaact tgttttttat ctgtatacat ttgatgaatt ttaaaattat atgatagata
    49501 gcctgtgata gtcacagtta ttcctgtcaa atttttttga ctagtaggaa gacccaaagt
    49561 ccctaatttt gcaccaatgg gctcttctag aattaataaa gccaagtcat attcccttgc
    49621 atccttagaa tttaaatttc taaattcctt caaataacga acttccttta ctttgatctt
    49681 tccaaatagt tcttgacttg gactaacagc cggaagaaca taaatatcat ccgcttcttt
    49741 cccatagtca tgtctgtagt agttgtgagc cgctgtaatt aacacattat ctttaataaa
    49801 attcgcactt cccctccctt ctacattcat tccatcggct actccataat acttagataa
    49861 aaccatagct gaagtcgaat acggatactg taaagtatta tcaattttaa tcaaatcatc
    49921 attaccgata atacttctga ttgcttttgg tagtatgaac catacgttgg tgaaatctca
    49981 gataatgaag aatcattaga ctctggacct ttttctagtg tctcacttac ctcatattct
    50041 tcacctgtac tagaaataac actcaaagca gatactgtcg ataactggct agccaataaa
    50101 gtactcgcaa taattgaaat acccaatttt ttataaacag ttttcttcat tattgtgtcc
    50161 tcctaatgta attatagcgt actattctaa atttcttaat ctactataga atcaagaaat
    50221 ctaccacctt ctttaaatac cctccattat cacataaaca ggtaaacttt tcaattaatg
    50281 actgcgcttt tcaatcacgc tagaggtact tacttgcttc tttgatacta agttcagcca
    50341 ttctttccct gtttttctca ataaagcatg ttacccaagt gggattcgtt ttggagtagt
    50401 ctcgcagagt ccagccaatg gctttattga taaaaaattc tgtttggttc aagttatgaa
    50461 ggagaatctt ttccattaat tgagtattgg tcttctcttt tcttaacaac tggtggtcaa
    50521 tagcgacacg tctcagccag atattatctg ataggctcca ttttatactc aatgaaaatc
    50581 aaagagcaaa ctaggaagct agccgcagat tgctcaaaac actgttttga ggttgcagat
    50641 agagctgacg tggtttgaag agattttcga agagtattaa gattatttct tctagttcag
    50701 ggtgttcata caccaaactc cctactactc gatctaggat atctaccgtg tcccaccagg
    50761 attttgtcac gactaactgc tctagcttag gcaaatcggt ttcctttaga taagactgca
    50821 ttgctttcaa atagttagca gccacatatt ggtattttct aggctccttt tcccagcaag
    50881 tgtctgcaaa atcccaatcg ataatctttg tttttttcgc ttctagtaaa tatttttata
    50941 gagtttattt ctttcaggca ccgcaatacc tagaaaagaa aattgatggc gcatataggc
    51001 ttccatggac cttgcttttt tagagtcttt tgctgcttct agctcctcaa gtaaatctgc
    51061 taaactcatc taaaactcat cttgccccac caaatggtgc tgaaaggcat agacagccgc
    51121 ctgggtacga tcgctgactt caagtttggc aagaatgttg gacacgtggg tcttgaccgt
    51181 cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct tggcgatgag
    51241 ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat gattgcggtg
    51301 gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag ctaccttact
    51361 gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt tggcaccagc
    51421 atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca aaatcttggc
    51481 ttcaggccat tctttaagga ttgctaaggt cgcgtcaatt ccattcatct caggcatgac
    51541 aatatccatg acaatgacat ctggacgcag ttccaaggcc aagtcaatcc cttgagaccc
    51601 gttggacgcc tcacccacaa cttctacatc gtcttggagg tcaaagtagc ttttcaagcc
    51661 caaacggacc atttcatggt catctactag taaaattttc atctttactc ctttatcatt
    51721 ccttatctaa caggggaata cggatatcaa ctgccagccc ttgcttggga gctgttaata
    51781 actgaaccgt ccctgccata tcttcaaccc gctccttgat atttcgcagt ccataactca
    51841 agtcgtctaa gctccctaac tggaaaccaa tcccattgtc caccaccttc agttgcaatt
    51901 caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg cggagcgtat
    51961 tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta ggcaatttcg
    52021 tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct tttaagagaa
    52081 tttgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa tgcaagagca
    52141 aaacccgcaa atccttctgg gctgtttcta aaatagctgt gacactctgc aactgggtct
    52201 gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa atcatgtggg
    52261 ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc ttccgttcct
    52321 tctcgatgat ttcctcttcc tgagcaaggc tatgattttc agctttttga agagcttctg
    52381 tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct ggatctgcaa
    52441 cctgaaccac ttcttgccct gccaataaac gcttgagatt agcctgcatt tttcttagag
    52501 aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggttatggac atgctgaaaa
    52561 ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtgcaaaaag atagaccagt
    52621 caaaatcaag tatttccagc aagttgtggg agaaaaaaaa gacaaacagg aaggaggtga
    52681 gagcaataat gacataggct tgttttttca tcctctaacc acctccacat caccaatcat
    52741 agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg tttcttgatg
    52801 atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat ccccatagag
    52861 acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg tcgttcctac
    52921 catctttctg aggataatga cattgtcatg attggttaag atgaccctct ccagatgaat
    52981 agtgtccttg cccatgaagc gaaagagatt gatatcatcg aattggcaag tctggtagct
    53041 tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg tcacgacctc
    53101 ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa gaagaaagag
    53161 gctatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca taacgatgaa
    53221 aaagaagaga atggttgccg ctactaaaag aagattattt ccctctttac cagtgtagta
    53281 gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat gctctgatac
    53341 catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga ttttaaattt
    53401 tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc acctcagtct
    53461 gaggatggaa aaaaggcgct ggttacgcct ttttcatctg atcctttgct tcttttaatt
    53521 ttccataaag aagatagtct actttttgta gatctgctat ggtggcacag ttaagggaac
    53581 acataatcaa gcgtaggtct gctttccagc cttggacaat gccaatcact tcttcaactg
    53641 tgtaggtttc aaccaattcc agaacggttc gtgacaatcc cacagactta gcaccaaaaa
    53701 ccaagcactt aatcatatcc agcggattcc gaacccctcc actaaccaag agttcgacct
    53761 tatctttcca ttcttgggca ttgagaaggg cctgcatggt agactgaccc cattgattga
    53821 ggtaatcacg ctggccacta cgacggtttt cgatataggc aaagctggtg ccaccacgac
    53881 ccgataggtc cactgtacga acaccgaatt cataggctct ttcgattgtc ttggcatcca
    53941 ttccaaagcc cacttccttg aggacaatag gaacgggaat ttgctcgcta taatctgcta
    54001 gatgcgattg ccagcttcta aacttccttt ctccctcggg catgagtaat tcctgcatga
    54061 cattgacatg cacttgcaat agaacaggat tcatctcttc tacagtctga agtcctaact
    54121 cgacaggctt gtccaatcca atattggttc caaggaggag attgggatga ctagacttga
    54181 cagaaaaaga atcatccgtt ggatttttga gggctgcgct ataagaaccc gttacaaata
    54241 aaataccaca ggattccgcc acctgagcca gcttttgatt gatttctctt cccttattac
    54301 ttccaccagt catggcattg atataaaaag gaaagtccca ctttcgacca gcaaactctg
    54361 tcgaaagatc gatttcatcc agattgtaaa gaggcaagga agaatgaatc agctccacct
    54421 catcaaagct attataggaa cttttctgct caagggcata gaggatatgc tcatccttac
    54481 gatttgtcgt catgtcctat cctttcttga tataagagct caatccccag atcggcccaa
    54541 cgatttttta aggtttcggt tgattgcgca tcaaaactca aggcgatgcc acagtcacca
    54601 ccaccagcac cactactctt ggcaacggcc tgcaaatctt gactggcttc tttcaactgt
    54661 ctaagcaaag gcgtgtaaat atctgtactc aagccttcta aaagcttgct ggctacttct
    54721 acttgctcga taactttttc ggctttcccc tgctccaagg cttcgaccaa agaaaccacc
    54781 gtttcttttg aggaacttaa aaaattttga ttgatatttt gcttgatttg ctggaccatg
    54841 tgactcgata cagccacttc cttggtccat cccactaaga aatcacattc taaagttggt
    54901 ttcacttgtg agataaaaaa tccccaatca cgctccagaa ctgtcgccaa gttttcttct
    54961 tctaaccaag cagccacctt ctggcgatca aatgactggt agagaaccaa atcctctgcc
    55021 acaatacagg caaggtcgcc catggaacca ttgtctcctc gcttgagcaa gacagcgcta
    55081 gtcagcttga acaagagatt ctgatcaacc gaaagattat agagagccag taaagccttg
    55141 acaaccaaga caacgacgct gccactagaa cctagaccaa actttttccc ttctcgttcc
    55201 attttgccac agatttttag ggaaaaaggt cttaaattct gaccgcgaac agcgaggaag
    55261 tctcccatca aagcaatcgt ttcttgaatc aagctgtagt caggattagg ccttaagtcc
    55321 actgcgaaat caaacatatc tgaatagata cggtagctgt cagaaaaagc aatttcagcc
    55381 ctcatataga tgggaatatc ctttatcaac gctaactgcc ctggctctaa aatagcatat
    55441 tcacctgccc aatagagttt tccgcaagtt ttaacagcaa tcatcttgac tcaaatcctt
    55501 tgtttttgac acaatcaagc gataacgctg accgaaaatt tctgataaat gctccaagtc
    55561 tttctcctga cagaagacct taacattggg accagcatcc atggtaaagt agcaggcctc
    55621 tcctttctca cgaagctggc gaacaaagtc catagcctca taagaggcat ccgtcagata
    55681 agaaaaggct ggactagcag tctttgtcgt agcatgcata gccagggcat ttttctccgt
    55741 taattctcca atcttggcaa aatcattttc cttgagataa atcagcatat cctgatagtc
    55801 cttctcagac tgacgaaccc agtcgtcgaa agtcgtcgag gtttccacac aaagtttcat
    55861 cccgtcacgg ctagagattg gttttttctt gtcctctagc accaacataa tcatagctag
    55921 tttcaagtct gtctctacag ggtaaatttc tccactatcc ttatcccagg ctcctagtgg
    55981 tccataaaaa ctccgagaag aagagcctga ggcaaacttg gcttcctgcg ctaactgact
    56041 tctatccaat ccaagcttga aataagcatt acaagccttg accagggcgg acaaaccact
    56101 agaacttgag gacaggcccg ctgccgtagg catattgttt tgagtatcga tacggacaaa
    56161 gccctcacca gctggacgat aacggtcaat aatcttactc atcttggcat gctcgacctc
    56221 attttgtagc tgaccattga tgtaaaattc gtcagctgtt acattggctg gtaaaggcga
    56281 caaggtcgtc tctgtataca tattttccaa agttagagaa atactgctag tagcaggcac
    56341 catctctttt tcttttttct ttccccaata tttgataata gcaatatttg cgtaggaacg
    56401 tactgttaca ggctctctat ccatgtctga acagctcctt tctcttctaa tctttctgct
    56461 agttcttgtg cgtgtgtcaa attggttacc aaggctatga tacaacctcc tagcccacca
    56521 ccgctcatct tggcacccag agcaccatgg ctaagagtcg tttcaaccaa aaagtctgcc
    56581 tcagggctac tgactccaat ttcttttaaa tgtaaatgcg cttgactgag gatttgtccc
    56641 agtccttcag catctttttg tgaaatcgca acttctgctt gctgggttaa ttctcccaag
    56701 gcatgcaaaa acggtagggc atccttgccc ttattttgaa ccacttggat ggcttcacga
    56761 gtatgaccat aaacacccgt atcggcaatc accaaatagg cggataaatc catctcaagt
    56821 tctgtaaatc ctacgttctt gataaagcga ataggttggt cactgagaca ggtcttagca
    56881 tccaaaccac taggattcat atgggcaatc atttcagctc gattgaccaa gatttctagt
    56941 acatcatgag gcagatcagc ctgatagtag tcaaataccg cacgaatggc cgctatgctg
    57001 atagccgctg acgaacccat cccccgtttc tcagggatag ccgagtcaat ctcacaacga
    57061 atgcaggctt ctgtgatatc caaatactcc agtgaggcat aaaccgccat ggacaaggta
    57121 tcctcctcat aaaggcgcca aggactctct gcaggaacta ccttacaggt cacctccacc
    57181 tccaaaagag gcagggaaat ggcaggataa ccgtaaacga ccgcatgttc ccctattaaa
    57241 attatcttac tatgtgcctg accgacacca actttttttg tcattttttc cttttactag
    57301 acgaaaaaac gtcttatttt tcatacaagt attaattctt tcctatctat tttattatat
    57361 tttcacaaaa aaagcgattg tttccattca caatcgcttc tttcattatt gagcccattc
    57421 gccattatag ttgacagaat agccatctac ggtcgtattc actgccaagg cacctgagct
    57481 ataagcgtag taccatctgc cattgacctg gaaccaacct gtcgtcatag aacgacgaaa
    57541 gaaactccat accattaagt aaagaggaaa gtcgtgaggg agcatgcgcc attgacaacc
    57601 tgttttagtg acgtacaaag tctcattaac aagtactcgt ttcggccatt tataggtgcg
    57661 gtgtttggag aaatagggtt caatcttcgc ccattcttga tcgtttaaat cagtatcata
    57721 tgctttacgt atcataactc tagtttaaca tttttttgtg aatacaggtt ctaaataatc
    57781 gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg aaacttatgc
    57841 acttaatttg acaattcaag atgtaaaaat atatactata gtagattgaa actagaatag
    57901 tacacctcta cttctaaaac atttttagaa atcgatttga ctgtcctgat cgatttgtcc
    57961 tgttattatt tcattttact ataatatttg ataagttatc ctaaaagtgt tattatgttg
    58021 ttgtgttata gattgattga atctaactaa aggatcctat tcaattacta gaactatcac
    58081 atactcaagg tcagctcaca gatgagcaac tattttggtt acaatgtcta ctaaatttaa
    58141 gtcaaacaaa taatttagtc aaaattaaaa aaatagagga acataaatat gattacaaaa
    58201 cagaatgtaa tagtgttcta cgatttttac tagataaaac tgtaaattct gaaggaagga
    58261 tcacttcttc aacagaattt ggaaatttcg taagtaattt atcattccaa cacggaatag
    58321 ctggactact gtttcctcta aataaattgt accccccaga actggattct aaaatactct
    58381 ctatcatcaa gaaggcagtg acaattagaa cgacacacac atatgaatat caatactcac
    58441 tgctatttgg tgatgcaggc tatcttttgg tgatgcaggc tatctatggt tactcctaca
    58501 tttattttct atcagtaaaa atcaatacta tctacaatta gcaaacgtca ccgctaagaa
    58561 attaatagag aattatgata ctctagagga aatagacttt gcattgggaa aatctggtgt
    58621 cctattatca ttaataaaat actatcaatt taccaatgac aatactctta aaactttcat
    58681 ccacaatagt atatggggaa atttatcatt atttcctaca aagagataca gccaaagaaa
    58741 gcattttaga ctatagcttt gctcatggat attgtgaaat tgcatatgct ttatttgcct
    58801 attctaaagt cttagaacct tctatgttct ataatgatct ccatacattc catgctgaat
    58861 taaaaaaatt attagaaaaa gttacttcta atactgaaaa tttaggaaat ttacaacttt
    58921 cttggtgcga aggaatttcc ggaataatct tatatctttg tatgtacgat tgtgacggaa
    58981 acaaagatat tattagtaaa tatcaagaat ttgtttttaa ccatcatcta aaaatgatga
    59041 caggatattg ccacggaata actagcttac tacaaaccac tgtctacaat caaaacaaat
    59101 tactgatgaa aaaatccaac aggtaatttt agcatgttct gaacgagatg atcacggttt
    59161 actgatgttt caaggagata gtggtaaaac agatttgttt gacttcggaa taggaagcat
    59221 ggggtatatt ggtgtctatt aaataataaa ttcccattcg atgtgcagac ataaggagaa
    59281 aagtatgaaa ttattttgga caaacaacat atatagacag ttgctgctaa acagctgttt
    59341 ttcatcattc ggcgacagta ttttctacct cgccattatc aattatgtgg ctcagtacaa
    59401 tttcgctccg ctagcgattt tactgatttc catttcagag atggttcccc tactatcgca
    59461 actctttctc gggattctag gagattttca agaaaataga gtcaaacacg cactctggat
    59521 tgccaaaatc aaaatcctgc tctacgctat tttgacagta tttctcgtct tgtcgccctt
    59581 ttcattagtt tcagtcatta tgattgtcat catcaacctc atctctgaca ccttgagcta
    59641 cctgtctgcc tacatgatga acgccctcta catcagtgta attaaggacg acctgcatga
    59701 tgccatgggg ttcaggcagt ctctgatgag ggttgtccac attgtcgcca atctggctgg
    59761 cgcattcctt atcaatgtta tgagtattca aactatttcc cttatcaaca ctctgacttt
    59821 tgtcattgcc tttttgggtc tgtatgttat tagacatacc ttgtatgagg ttgaaaaaag
    59881 gattgaaatg tcacatacag cactgagttt taagaaatat tttcaacatc ttaaacagtc
    59941 gctggctgtg ctcctgaggt taaaagatac cgtcatacta ctgtttctga cgaccagtat
    60001 gattgccatc ttggatgtgt cccctcggct gattgccctc cgcttcatcc aacagacact
    60061 agcacaactg agcattgggc aactcctcgc catgctctcc atcatcattt cttgtggagc
    60121 tatccttggc aatatgacca gcagtaatct atttaaaaat atccgtttca cgcacctctt
    60181 ggttttctgt gagatttccc tattggctct aataactagt atcctttgtc aagcctatat
    60241 cgtaattttc atgaccagtt tcatcagttc tacgattatc ggcattctca gccctcgcct
    60301 acaagcagct gtctttgccc atatccccag tgacaagatg gggacggtgg gctctgctct
    60361 gagcacagta gacattctcg ccccgtccct gctctcccta ttagccctgt ccatagcatc
    60421 gggcgtttcg gtgcagttag cattgatatt tttgtatctt attttgattg ctcttatctt
    60481 ttgtcaatgg ttagtcaagt tcaacactca taactaacga aaaagcatgt gtagatttca
    60541 catgctttta atctccccaa tcgtcaggtc aagtacaaca aagtcacttc tttgattaag
    60601 cgagtgttct aatataatta taagcgccct gtcattaccg aacccattcg ccattatagt
    60661 tgacgtagta gccatctacg gtcgtattca ccgccaaagc acctgagcta taagcatagt
    60721 accatttgcc attgacctgg aaccaacctg tcttcatgtc tccattacct gcatttaggt
    60781 agtaccaagt taaaccatct tgataccagc cagttaccat tgctcctgat gaacggaggt
    60841 agtaccactt gttaccaagg tattgccatc ctgttttcat atcaccattt ggctggtcta
    60901 aataatacca agtggtacct tcctgatacc agccagtggc cattgctcct gatgaacgga
    60961 ggtagtacca gttattacct agatattgcc atcctgtttg cataatacca gttgttggat
    61021 ctaaatagta ccaagtcgaa tcatcgttta tccaccccgc acgtctttca ccaccaaggt
    61081 agttttctcc attaatttcc gtcttagcta gataatacca gttagactga tcataaagcc
    61141 aacctgtctc taaagaatga ttttgattaa agtaatagtt cgtataataa cgcttctctt
    61201 ctttatcttc tgaatcttca cgtttttccc cgtactttct tccaacactg tctttagttt
    61261 taatctctaa tgttttccaa ccaacaaact cttgtagcac tccattttta tcgaagtagt
    61321 accactctga ctttggaaaa ccttctaatc tgataccatt tgggtaagga ccaattgtac
    61381 tacctttaga tggaaacggg atatattgcc agccgacaac catctctcca gatagagaat
    61441 caaaataata gtacttacca tcaatcactc gccagtaggt ttctttgagg tccccctttt
    61501 tgtagtaggt tcttccgttt tcttggacaa actgccatcc ttcagaatca tctgcaaata
    61561 ctgtactggt ccctagcaaa ccaaagaaaa agactgctaa tgcgattggc atcatttttt
    61621 tcaaaagctt cattttatat atcctcctaa aacgattgta gtaaaaacta gattgtatgt
    61681 caatatataa aaactcctca aaaaagcagt tacacaactg caactgcttt tctattcttg
    61741 catggtgtaa ccaacaccac gcacggtttt aatgtagctt ttttggcctt taacatcaag
    61801 cttgctccgt agatagcgga tatagacatc tacgatattt gtctcggtcg cactttcata
    61861 cttccaaaca ctttccaaca attgctcacg agtcaatact ttcttgcttc ccataagtgt
    61921 cgccaaaagg tcatactcac ggcgggtcag agcaatcatc tcttcaccac gataaaccgt
    61981 gtgatgttca acatctatcc taagattgcg gtaggtcctt ggaactttca tcagactgca
    62041 gtgttgatca atgaagtccc gacctcggaa gattgccgaa atacgcgcta ccagattttc
    62101 gataaagact ggcttataga tgtatgaaac tgcaaaacgc tgaacaactt ccagctcttc
    62161 ttgcaagtct tcccaatgat ctaaaatcat gatgactgag gcaggtttag ttcgactcaa
    62221 tttttctgca aaatcctgag ccatcatatc tcccagatta acgttcaata aaatcaaatc
    62281 atagtctgtc tgaagagcca tggaaagggc tttttgcccc tcctctacca gatcaacccg
    62341 atactgctct ttctggagtt ccaaacttaa aaaatgagct agatttcgtt ctttctcaag
    62401 taataaaatc cgtttcccca tggctgacct acttattttt cgtcatacca agagtagtgg
    62461 aaggttcctt ctttgtcttt acgttggtaa gtgtgagcac caaagtagtc acgttgtgct
    62521 tggatcaagt tagccggaag gtcagctgaa cggtagctat caaagtaagt aatagctgct
    62581 gagaaagttg gcactggcac accagcttga accgcaagag ctacgatatc acgcactgct
    62641 tgttgatact tagcagtaac atccaagaag tactcgtcca aaagaaggtt ggcaagatct
    62701 gcatcgcggt tgtaagcatc tgtaatcttt tgcaagaaac gagaacggat gatacagcca
    62761 tcacgccaga tagatgcgat atctgcaaat ggcaagttcc agttgttttc tttagaggct
    62821 acacgcaatt gagcaaatcc ttgtgcgtat gaaatgattt ttgagaagta aagggcttga
    62881 cggatttttt caatcaattc agccttgtct ccttcaaagt tgaaggcagc tggttttgga
    62941 agcaccttgc tagcatgtac acgttcttct ttgtaagttg aaatgtagcg tgcaaacact
    63001 gactcagtaa tcagtgacaa tggtacacca aggtcaagag atgattggct cgtccattta
    63061 ccagttccct tgttacctgc agcatcaagg atgtagtcta cgattggtcc atcttggtct
    63121 tcatcgtctt tacggctcaa gatatcagct gtgatttcga tcaagtagct atccaattca
    63181 cccttgttcc actcagtaaa gatttcagcc atatcctctg cagaaaggcc tagcaagtgt
    63241 tgcatcaagt catagctttc tgcgatcaat tgcatatcac cgtactcgat accgttgtga
    63301 accattttca catagtggcc agctccatca ggaccgatat aagtcacaca tggtttgcca
    63361 tcttctggtg ctttagctga gatttcttca agaacatccg aaaccaattc gtaggcctct
    63421 ttttgtccac caggcatgat agaaggacct tcaagggcac ctttttcacc accagaaact
    63481 ccagtaccga taaagttgat acctgagttt gccaattctt cattacgacg gatggtatct
    63541 ttgtagaaag tgtttcctcc gtcaatcaag atatcacctt tgtcaaggtg tggaagaagg
    63601 gcttggatag tagcatctgt accaggtcca gcttgaacca tcagcatgat acgacgaggt
    63661 ttttcgattg agtttacaaa actttcaacg tcatagcttg gtacaaaatt cttttcagga
    63721 tggcaagcaa tcacatcttc cgttttttct ttactacggt tgtagatagc aactgtgtaa
    63781 ccacgtgatt caatattaag ggcaaggtta cgacccatta cggccatacc tacgacacca
    63841 aagttagctt ttgtcatttg acactcctct tgtttcattt gttttatttt atcattttta
    63901 cttttgaaaa gaaagaattt tgtaacgact gcttagtagt ccaagtcatc cgcatgacca
    63961 gcgccatttc cgacaaagta gcctgtctta cagttaaggg taaagagata ggttccatct
    64021 ggcttataga ggttgtaata accattgccg ttaacgatat tgacacgttc aaggatatat
    64081 tggtctccag tgatatagcc acgtgaacgt gaagttgcta gaatttgttc caaaacacca
    64141 tccgcaaaat cccaggcaga gttattacta tcatcaatag cagactgatt ataggcaaca
    64201 cgactggcac ttctttgaac agcaacccct gcactcgaga gacccatatt gacttcactg
    64261 cgactacttc tagtctcatt tgaactactt ggttttggct cactagtcgt atttgaactt
    64321 gcttgacttg aacttgagct gctagtttga cttgaacttg agctagaagt acttgtttgc
    64381 tggctcttac caagactgat agccttatct agcactttat caagctccgt atttccagtt
    64441 ttaatatccg taaatttagc atccgatttg gctttggcat tggtatccaa cacaccatcc
    64501 acaatagctg gtttttcaaa ttgtgcattg acatcttgaa tagccttgat ttgcgttgct
    64561 agactatcat atttagattt ggcaagcgta tgttcacgac taccttccag cttatcaagt
    64621 aaagtcttga gttgactcag tttatcaaac tggctatttt tcaaagccgt tttattgcta
    64681 tttgtgtaaa aggcgtcata aagtgtatta aaatcatcca catccgactg attggctgta
    64741 gttgattgag aagtttcaat ttccttggtc gaacgagcca cttgacgata gacataataa
    64801 gcactgacac aaataattac tgatacaagc gccaaaacgg tcaaaataaa gcctttttta
    64861 cttttctttt ctgagtcctc ttgatccaga cgagaaaggt tttgctcctc ttccacttct
    64921 tcagtcattt ctgttggatt ttcatcatct agcaatagag gatccaagcc ttgctcctca
    64981 tcgtccagag gcaagggtag taagatgtct tcagaagatg gaacttcctc cgaagaagct
    65041 tctgacttct ctacagcctc acgcatctct tgaattaaat catccagact ctgagtttca
    65101 acgaactcct cttttttgta ttgacgagtc gcaaacttat ccgcctcaat ttcatctctg
    65161 tgttgcttaa catacttgtc caaaatggaa tcctcaggca agactcctgc ttccacttct
    65221 tcatttttac gaatagcttg accaactgtt agctcttttg cttcatcaaa atcaaattgc
    65281 ggttcttgag cttctttttt atgacgattt cgtctttttt tactcatgag tatccctttc
    65341 tattttacct cttgccgttt gacacgctga ccaaaatatt gatataaatc cactttcaag
    65401 gttccgttgt ataacttacg cttcttatct gcttggctac catacttgct ttcaaaagct
    65461 tcatcactag tcaggataaa tttgctccaa gttttcagcg gtgcaaatac ttgccccatc
    65521 tcagcataga gcttggtcac ccctgcatca tctgacaaac gttcaccata aggcggattg
    65581 gaaatgatta ctccattgat tttatcggaa cgtaaatcct gcacgcgcat ctgcttaaaa
    65641 gtaatgtctc ctgcaacacc agctgcctga gcattggcct tagcaatttc caccatgcga
    65701 gcatcaatat cacagcccat gatatccagc tcaagctcac gttctacttt tttagccgct
    65761 tctgtgcgca cttcttgaat caagcgatcg ctgatccagt tccattcctc aaatgcaaaa
    65821 gagcgacgaa gacctggcgc catctttcta gcaatcataa ctgactcaat acagaaagtc
    65881 cccgaaccac aggtcggatc aatcaaaggc ttgtctgggt accagttaga aagttgtaaa
    65941 atggctgctg ccatattttc cttgatagga gcgccacctt tttcggtacg ataaccacgt
    66001 ttaaagaggc tagacccggt cgtatcaatc atgacagttg ccacatcttt gagaatagag
    66061 acctcaatct taaactctgg gccattctcc atcagaggaa ccccttctgg gcgagcatag
    66121 tgtttctgca atttcttgac aacagctttc ttagaaatag cctgaacact aggctcattg
    66181 tgaagtttgg acttaacaca tttagctttt gaaatcggga accgagctcc aagtggtaaa
    66241 taattttccc aatctaaagc gaaaactccc tgaaacagct cttcaaaagt cttagctggg
    66301 aacgttccta cgataatctt gatacgatct gctgcccgaa gccacaggtt ggtttcgata
    66361 atagttctca cgtctccttg aaaacgaaca cgaccatttt caacctgaca atcgtagccc
    66421 aactctcgca cttctcgtcc cacaacagct tcaagacctg ctgccacagt tgcaattaaa
    66481 ttaaattctt ttttcatgtt acagtcttgc aagacctttc tatatgtcca ctttaaaaaa
    66541 tgaggttgag aaaatttctc agccccaacc tatatgcaat tttctataag ccatgttttg
    66601 ttccagaagt gactaggacc acttccttcg ataatcatct gtctaccact agcagctcta
    66661 gctgatagca gtcagaatac tacgttcgtt tccgcgtact ccatgccccg accaaaattt
    66721 gggttgctag cttgaggggt ttaccgcgtt ccactctctc tgtttccaga aagactccgt
    66781 cactgtggca ctttcaagcc tactctggcc tatccaagga cttagccatt tcaactgccg
    66841 taacgatttc tcgtccctag gcttatggtt tcgcctagca caaacactac aggcatcaca
    66901 gcctgtgcta gcatggactt tcctcatgag aagcaattct cctcacgcga ttatccaaaa
    66961 attgcatgta acaagacctg aattacaaat cagtattgtc taaaatttgt ttaccgaata
    67021 cttctttttc aagacgattc aagcgtttca aaatatcaaa attcgtcata gaagatgaag
    67081 cagccacatc aattggatct gggtgactag gacttggagc cgaactcact tgcggtttac
    67141 gagttaattc ttccttcaaa tccgcaatct cctgacgaag tgacttaacc aaggtagcat
    67201 aggtttcata gtccttgatg acatcgtcta aaaactcatc aacttctacc ttgctatacc
    67261 cacgaacttc acgtccaaac tcttgttcaa aaatatcttt tgctgaaaaa ataatacttg
    67321 tcatgtctct ctccattctc gcttgctagt attattatat aaaaaaaggc aaacaaaaat
    67381 caaggtcaaa gcttcaattt tcggaaaaat tttcagcaag ttcatttaat tgatcaaatg
    67441 ttaatctctt tataaaatag tcctcttgat ttttcatctt ttggtaaaaa taagctagtt
    67501 tcgtttcatt ttcttcatca taaaaaagat aggaactagt cgtgttttcc agcaaaaact
    67561 gctggtaatc tcttaactgc cccttgtgct catagcgagg ataagcatat ttgacaaagt
    67621 ctacctgctt aaaacgactc agtttcatct gattgccttc attccaattt tccccatggg
    67681 tttcaaaagc aaaaatggtg gccaactgga aaccgtactc ggttttcatc tcctgagcaa
    67741 cctctaaaac ccaatattca aaacccaaac ttcctgtaaa cacaagccaa gacaccccat
    67801 ctgctgccat agcctctaaa tctttacgta ttgctttttt tatcaattta agacgaggat
    67861 ccttatcaga aaacaaaccc aaatcaaaag cagaatagcc caaaaccaaa gctgtagcca
    67921 tttttaaccc tttctgtgca aatttatggt ataatagagt gatgttattg taccaataag
    67981 gagaattatg gtcaactatc cacataaact ttcatcacaa aaaagacaac catctctttc
    68041 tcaacccaaa aatttcgcaa atcgaggaat gtcttttgaa aagatgatca atgctaccaa
    68101 cgactactat ttgtctcagg gcttggctgt tatacacaag aaaccaactc ctattcaaat
    68161 cgtacgagtg gactatccac aacgaagtcg tgccaagatt gttgaagcct attttcgaca
    68221 agcttcaacg acggactatt ctggcgttta taatggatat tacatcgact ttgaagccaa
    68281 ggaaacaaaa caaaaacgtg cgattccgat gaaaaatttt catccacatc agattcagca
    68341 tatggaacaa gtccttgccc aacaaggaat ctgctttgtc cttcttcact tttcttctca
    68401 gcaagaaacc tacttattgc cggcattcga tttgattcgc ttctatcatc aagataaggg
    68461 acaaaaatca atgccacttg gatatattcg agaatatgga tatgaaatca aggctggtgc
    68521 cttccctcaa attccttatc tcaatgttat caaagaacat ttattaggtg gtaaaacaag
    68581 atgaacaaac caacgattct gcgcctaatc aagtatctga gcattagctt cttaagcttg
    68641 gttatcgcag ccattgtctt aggcggagga gtttttttct actacgttag caaggctcct
    68701 agcctatccg agagtaaact agttgcaaca acttctagta aaatctacga caataaaaat
    68761 caactcattg ctgacttggg ttctgaacgc cgcgtcaatg cccaagctaa tgatattccc
    68821 acagatttgg ttaaggcaat cgtttctatc gaagaccatc gcttcttcga ccacaggggg
    68881 attgattcca tccgtatcct gggagctttc ttgcgcaatc tgcaaagtaa ttccctccaa
    68941 ggtggatcaa ctctcaccca acagttgatt aagttgactt acttttcaac ctcgacttcc
    69001 gaccagacta tttctcgtaa ggctcaggaa gcttggttag cgattcagtt agaacaaaaa
    69061 gcaaccaaac aggaaatctt gacctactat ataaataagg tctacatgtc taatggcaac
    69121 tatggaatgc agacagcagc tcaaaactac tatggtaaag acctcaataa tttaagttta
    69181 cctcagttag ccttgctggc tggaatgcct caggcaccaa accaatatga cccctattca
    69241 catccagaag cagcccaaga ccgccgaaac ttggtcttat ctgaaatgaa aaatcaaggt
    69301 tacatctctg ctgaacagta tgagaaagca gtcaatacac caattactga tggactacaa
    69361 agtctcaaat cagcaagtaa ttaccctgct tacatggata attacctcaa ggaggtcatc
    69421 aatcaagtag aacaagaaac tggctataac cttctaacta ctgggatgga tgtttacaca
    69481 aatgtagacc aagaagctca aaaacatctg tgggatatct acaactccga tcaatacgtc
    69541 tcttaccctg acgatgattt gcaagtcgca tctacggtcg tagatgtttc aaatggtaaa
    69601 gtcatcgccc aacttggagc tcgtcaccaa gcaagtaacg tttcatttgg taccaaccaa
    69661 gctgtggaaa ccaatcgtga ctggggttct gctatgaaac caatcaccga ttatgcacct
    69721 gccatagaat acggtgttta tgattccact gcaactatgg ttaatgatat tccttataac
    69781 tatccgggaa caagcacacc tgtctacaac tgggatagag catatttcgg taatattact
    69841 ctgcaatatg ctcttcaaca atcacgaaat gtcacagccg ttgagacttt gaataaggtc
    69901 ggtctagata gagctaaaac cttccttaat ggtcttggta tcgactatcc aagcatgcat
    69961 tatgcaaacg ccatttcaag taatacaaca gaatctaata aacaatacgg agcaagtagt
    70021 gaaaaaatgg ctgctgctta tgctgccttt gccaacggtg gaatttacca caaacccatg
    70081 tatatcaata aggtcgtctt cagtgacggt agtaaaaaag aattttcaga tgtaggtaca
    70141 cgagctatga aagaaacaac tgcttacatg atgaccgaaa tgatgaaaac tgtcttggca
    70201 tacggaactg gtcgtggagc ctatctccca tggttagcgc aagctggtaa gacaggtact
    70261 tctaactaca cagatgatga aattgaaaaa cacatcaaga acactggcta tgtagctcca
    70321 gatgaaatgt ttgttggtta tactcgtaag tattctatgg ctgtatggac aggttattcg
    70381 aatcgtttaa ctcctatcgt tggagatggt ttcctagttg cagctaaagt ttatcgctca
    70441 atgataacgt atctgtctga aggaagcaat ccagaggatt ggaatatacc agaggggctc
    70501 tacagaaatg gagaattcgt atttaaaaat ggtgctcgtt ctacgtggag ctcacctgct
    70561 ccacaacaac ccccatcaac tgaaagttca agctcatcat cagatagttc aacttcacag
    70621 tctaactcaa ccactccaag cacaaataat agtacgacta ccaatcctaa caataatacg
    70681 caacaatcaa atacaacccc tgatcaacaa aatcagaatc ctcaaccagc acaaccataa
    70741 catttatcac ccagattttt ctgggtgatt ttttcatagc actattgtat ttatgtgctt
    70801 aacaaaagcc tgagaagata tcttcttagg ctttttctgt actataaacc tcattggaaa
    70861 agatagagac tacttccgta atcttgttaa gaggttttac taaatactag tctttcttcg
    70921 tttttactac aaagagagca gatagggcta ggctaacacc tgctaggaag agggctgtgt
    70981 cagattgact ctcacctgtt gctggcaaga tttgttcagg tgtttctggt ctagctattt
    71041 cttgcttata atctggcgtc ttaccttgat cggaagctaa agagctaagt ttaaactcag
    71101 gtttctctac agttggagca tctggtttcg tagcagaatc ttttaattgg ttgagataat
    71161 ctgcaaagta ttccaccatt ctttccgtca agagatggtt atccgtcgca tatttcatgc
    71221 ttgcctgaac gctagctact tcctcttgat tgtctttgtc tgttaatttc tgagccttag
    71281 ccaaagctgc ttcatagcct gacaagtcaa gaggtgtttc tgctacctgt ggacgagtaa
    71341 agataagttc cgctgcagat tggtatttat cgccaccatc tccgtaagtc ttagtacctg
    71401 taaggacaat tttcttagcc ttaattgtct taccaaaatc aatgtctttt ggcttattgt
    71461 tatctggcca atcagttgca gtaaaggtat gctccttgcc agactcatct gtcacaacaa
    71521 gtttcacatc acgcaagtta ccatttgaac ctgatccacg tggaacataa cgaagtccag
    71581 tgatttcagt tgcttctttc aagaccatgg ttgcaggctt gcctacatct cctccgcccc
    71641 atgatgtatg ccatagacta gacacattgc catcaaaagc attctctagg ccttcacctg
    71701 gttgagctgg cgcatccaaa ctttcaaagt cttctgctac caaagccgtt ttcttctgaa
    71761 ccaaagcatt cttcaaggct tcaatcttgg caatctctgc acgcgcttct tccacactga
    71821 tatcatcatc ggcctgactg aggttaaaga ccgcctcttt caaagcatcc atagactctt
    71881 tggtgtagtt agtcatggca accgttggca agtagttctt cagagcattt tctgtcaaca
    71941 tcttacctgt tagggtaatt tcttcgattt gaagattatc catcatgaag tcgttataac
    72001 cacggaagtt ggcatttcca ccagaatcac cacgagtatt acttgcattt ccagttgagt
    72061 agatacctac ccaagtatcc cctgtttctg cacctgtcac gaggaaggtt gccttcttgg
    72121 ctttcttaga atctgtccaa gtatttggca attcatgcat ttccaagttg cttgcttgag
    72181 tgccacgacg acctgactgg aattctccct taccgactac aaaagcatag gtattgtctg
    72241 aacctgcttc gtattcaaag gttacacggt aggtcttacc tgcttcaaaa cggaagtttt
    72301 gcggaatggt ttggtaaacc aagttacgac ggctcactag tccatttgtc ttgagtgacc
    72361 aatttccttc gataacatca tcgactttct taccgttcca accacgttgt gtatatggat
    72421 cgtgtttttc agacaagtga gtgcggttgt cttcgacacc ttcgacacca cccactacaa
    72481 atgggaagat accctgagca acattttcaa agtcttgctt gaaggtgcct ttacctgtat
    72541 catgcttgtc tccgtacatg cttgaattgt tttcaaaggt acgaatttca tcaaagtaag
    72601 ttgcttcatc accagcttca cgactcaatg tcagagtaac atttgagacg tccgatccag
    72661 ttgtaaagaa ggcgtacatg ttttggaagt aacttgtatc gtcaactgta gcattgttac
    72721 gacgtgtatt gtgggcgtag gcttttacat agttgagggc gagagactta ttggtataag
    72781 tagtcacttc tttttcacca gtattcacag tgatacttgc cttggcatta ctacggttat
    72841 cgacaccgac ataaacggca tacttagtat ttggtttcaa gccagttaat ttctgaatga
    72901 gactaacttt ttctttgttt ccttgaatac gaagcatatc gtttgcccct tgagacttga
    72961 caatttctgc cttagaagca tcaccagaaa tggtccagtg tttcaaggtt ccactgttaa
    73021 atccttggtc atagatgtgc atgccttcgc tccatgacat ttcaggattg gtttgtttcg
    73081 aacgatagag aacgtatggt tgatttgcta gaagatctag ggtaatttta ccatctttta
    73141 cagttagttc ttgctcttct gtcttacctt ggtcagttag cttgtaaagg taaaccttgc
    73201 tctttgccca atcgcttgga agggtccaag ttgttgcacc ggcctgcgta ttgaagtagt
    73261 acatcttttc cttatcagta gaaagtttct taccatttgc atcccagttc caaggagtca
    73321 agtaagctga accatcttgg atgacacgtc cgttgagcgt tactgtacgt tcgcgatatt
    73381 gtggactatt gacatcattt gacttacgag ttacaactac tttattattg tcagcatcta
    73441 ccaattccac tcgcatttct ggagtccatt tataggtgct accgttatcg gtcatagtca
    73501 ccggtgtacc attttcccat ttgcttacag tgaagtgttg gaaatacttg gtcatgacgt
    73561 catgggcaaa taagttggtt acatagccat tgtagtcact tcttccttgc cagccttcaa
    73621 agtctttcat gctgtagcca cctagcagtg gatagttggc tgcaccacca taacttctgt
    73681 agtccccaac ccaagcatct ttttggtggt tacggataaa gcgggtgatg gcactgttga
    73741 tacctttatt ggtgtagcca ccgtaggtca agtcagctgc ccagtgatgg aaggtagagt
    73801 cgtactcacc accatggccc cactcgatcg caaagcgcca gccttgtttg ttaatttctt
    73861 tagcaagaac gtgggtagcc caggcaccgt tatcacctga ttgaccatta ccccaaacgt
    73921 ccacatagat aaagtcgaga ccgtcaccaa gttttttctt caaatcttcc caacgtgcca
    73981 aacgaccatg agctaggtca taggcagcat caatgttgat accttgatct agccagttcc
    74041 aaccatagct atagcttcca tctggattct tacggagaat tttttcattg aaatatttag
    74101 actcaggata agtttctgaa gcgttaacgt ggatacctag atgagctcca tatttcttag
    74161 ccttctcaat tagggtcttg aagtcttcga caccaccgat acgcttacca atatcagcat
    74221 agttcaagtg accagagtca tgaccttcac taccatatcc tttaaggaga acaccttgcc
    74281 caagaccatc tgtgtggaga ttgattttct tgataccatc caaggtcata aggaatgggt
    74341 tttgtgcttg agaaccaaag ttcatcgcga tacggtaagc tgtgatatcc ttaacttttt
    74401 cccaaccttg agggttgttc ataatgctac gataagcaat ggcaccatct tgccaatcaa
    74461 cgttcttgtc tgcattggca tcttcagtga taacaacctt agcactcgga agttccttcg
    74521 tgtattctgg gaaaacaatg cccttataag ctttttccca ttgccattca gagctgtgga
    74581 ttcctacata gttggcattt ccgactgttt ctttataagc tgtcaaacga gtccagtcat
    74641 tcgaaccacc accatagctg ttttgagagt tactccaaac accagcagca agcttatctg
    74701 tagaaacaaa tccatacatg taacccttgg ctaggtcttt cattggattg gttacatcga
    74761 tatgatcatc tccgctgaca tgcgtattgt ttgacatggt tgccccatca aacttagcac
    74821 cagtttgatc actagaaaca gagactaaag cattgccgag gaaactaata gaagaaagta
    74881 gttttctttc gtcatcaatc ttttgacctg gagtgacttg attgtggttg acaatcttgg
    74941 tcacatcaaa gtgcaattga ttgtccacaa cttgcaagcg tactgtcatt tccgcattga
    75001 ttaagtgagc atcatcgcga agcttcatca agtactctgc tgttgtctca ttgattttct
    75061 tataagtgac ttcaggggtg attcggtggt tattgataaa gacttggttg aactgttgca
    75121 cctgtcctgg caaagtatgt ccattcaagc tgtattcctt gacacgaggg aaggcttggt
    75181 caatcactgc tttgaggacc ttagactgaa tcgtgtcata agtcaccttg ctatcatcaa
    75241 cttcaggacc tgtttctttt tcagcagggg tatcctctgt ttttaccccc tcttggttat
    75301 ccgttttaac gctaacaact gttcgctcat cgtcataaga gcccgccttg agaagaatct
    75361 tcttctcatt tttaagatgg tcattgaccg cagctggtag agtcactgtg tcaaagagat
    75421 tgacatcgtt attgctggca tttagctgac cgtctgactt gagagtgata gagagacggt
    75481 ttgttgatcc tgtttcagga gcagcaacac gactacctct ataccaagtg ctagttgttg
    75541 gagatttata ctcccagaac cagccatcct tgtcataacc gacaaaaaca ttattattgg
    75601 tatctttaaa tttcaagaag acaccaaagc gtgatttgcc cttttcagaa tcttctttga
    75661 aggttaaatc aacagttgca tttccattgg catcaacggt caagcccttc ttttcaaaca
    75721 gggctggttt gcctgcgtta tcattttgag cagttgagga tagttggttg tagcggacac
    75781 ctttttcttc tcggatagtg actgttccct gttgttcttt tttctctacc gtttgccatt
    75841 caggggttac cgtcttaagt gtttcaggtt tagcagctgc atgtttatcc tcttttggtt
    75901 tttcttcagc cggtttttct ttttcaagtg ctaatagttc ttcttctgtc ttaggtccat
    75961 ctgtgacttc tggagaacct tggtcttctc ccaccttagg cgcttcaaaa tcacgcccat
    76021 cattctcttt tgctgttgca agagcagtag ctaaatcagc tggtaagttc gccgtggaac
    76081 cagactgcac gctatctgca agaaccggac ttgtcccaaa gaatgcagct ccaatcataa
    76141 cagaagcaac acctaatgaa aatttccgaa tactatattt acaacgtttt tcaaataatc
    76201 ctttattcat aaacttctaa atcctttcat ttttgagcaa gcgtttacat tttcttttta
    76261 aaaaatactc cttcctctga aagtgcaatg cttaacccta ataaataaaa aataattata
    76321 cttttaatat aacaaataat aactgagaaa gcaataggaa acaagtaaaa ttaacaaaaa
    76381 ttttctctat tctgacaaaa agaggctcta acttttgggg gtcagtacat ttagaatctt
    76441 tctttacaaa tgtaaaaaag gattcagcat tcaagagaaa tactaaatcc tttcttatat
    76501 tttgcaacag ttatttcaca tgttttgcga gatcttcttg agtcttttta ttagactctt
    76561 ctttttcttt catccatttt tcctgagctt tttggtattc atctacagtg actgccttgt
    76621 cttgaagttc caagtattta tataagattg gttcacttgt acctttattt cctgacaatg
    76681 caaatggtat tgtaaatggt accatcttag acaagattgg gcgccctgta cgagatgtag
    76741 ttggaataat caaagcacta tctgtcaacc aagcttgggc tgcagcgtat ttatcatagc
    76801 gtttagcaac atctgtagcc tcatcaccag cctcagtgac caatttttcg tagtcatata
    76861 gacctacttt tttagcagct acattatctt cccctgagtc aaaccctaaa tatgttttag
    76921 tactttctcc tacagatggt ttgatgatat caaggtaggt tgatggatcg gcaaagtctg
    76981 gaccccaacc gacattatct gataaatccc agtcttcgcc agcagcattt tcagcaaaat
    77041 atgtaatatt gtttacttcg tctttttgta gttgttgaat atcaatgact acattatccg
    77101 ctcctaaagt tgcttccaag gattgtttca tagattggac gcgctgaact tttgtagttg
    77161 ctgtttggtc aactggcata tccaaatgaa ttgggaattg gactccttct gcttgtaagg
    77221 ctgatttagc tttagcaaat tcagccttgg ctttttctgg attgtaaaga ccatcctgag
    77281 aatctgcaag attaacatcc ttccattcat ccccataagt gaccaatttc tctttgacca
    77341 tatcgccaaa gtttttacca tctgcttgaa caaatgttgg tggcacaaag agattacgca
    77401 agattttgct tgctccagtt tgtccattca actgagaggc ataggctgta cgatcaaaac
    77461 caaaggcaat agcctgacgg aaatccttgt ttaagagagc ctttttagtc gatgcctttt
    77521 gttcgtcgct ggtcttagat gtgtatttat aggactgacg gtcaatattt gtaccaacta
    77581 gatacgtaat agagtcttgt tgagtataga caatattgtc cttcatactc ttctcaagct
    77641 ctgcgaaact tgcacttgtt ggatagagac gagctgctgt aaggctacca tctttaaagt
    77701 tttctgcagg tttgctggta tcttgaccat cccagaatga caatttaact ttgtcaacat
    77761 gcacattgtc cttatcccag tagttcggat ttttcgcaaa ttcaacagag gattttgtca
    77821 caatggattt caacaaataa ggaccgttat acaagagact acttggatcc gtcgctttgg
    77881 caaaatcatc cccttttgag ttcaaaaact cttcattaac tggcgcaagc acacccatgg
    77941 ttgtcttaga attccagaag ctttctggtt tgttcaaagt gtactgaact gtctgatcat
    78001 ccaaagcctt aattcctact tgtgagaaat ctttgatttc cccttttaca taggcatcca
    78061 accctttgat tgattcttga acaaggtaaa gagcatctga ttttttatca gcagcatatt
    78121 ttagtcctgt tacaaagtct tgagctttga ctgccgcgta ttcttcacct tcagaagtat
    78181 accattttgc atccttacgg atagtataag tgtaagtcaa tccatccttg gatacagacc
    78241 aatcctcagc catagacggc acaaagttcc cgtagcgatc attttctagc aaaccatcaa
    78301 ccacgttact ggtaatattt gctgtcgcag ccttagcagt tgtcaaatag ttgaggttat
    78361 cagggtctgt ctcataaatg tatgagaatg tcttctcacc tttagtgctt gaacctgatc
    78421 cagagcatgc agctaaagta gtcgccgcca ataatgtcac gcccgcaagg gcaaatagtt
    78481 ttgaactttt catcattttc tcctttaaaa ctttctctcc attatagact cttttcagaa
    78541 agatgtcaac agaattttca gaatttttga aaattatttt tcaaacaaca tctttgcaaa
    78601 aaatatgggc tctacaatat ttgtagtggg taaatccact atagatatta tggagcctat
    78661 ttttgtgtag aaaaaaagtc ccataagatc tataatgaaa agcgacaaaa caactcatta
    78721 gaaagattca tatggaacaa ttacatttta tcacaaaact actcgatatc aaagacacaa
    78781 atacccaaat tatagatgtc gtcaataggg attcacacaa
//
LOCUS       DAVLIK010000003        71714 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLIK010000003 DAVLIK010000000
VERSION     DAVLIK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.003"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(55..378)
                     /gene="tnpB"
                     /locus_tag="VXE87_000177"
     CDS             complement(55..378)
                     /gene="tnpB"
                     /locus_tag="VXE87_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0841797.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(359..544)
                     /locus_tag="VXE87_000178"
     CDS             complement(359..544)
                     /locus_tag="VXE87_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841798.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(848..2410)
                     /gene="guaA"
                     /locus_tag="VXE87_000179"
     CDS             complement(848..2410)
                     /gene="guaA"
                     /locus_tag="VXE87_000179"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0841799.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2552..3250
                     /locus_tag="VXE87_000180"
     CDS             2552..3250
                     /locus_tag="VXE87_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0841800.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3293..4189)
                     /locus_tag="VXE87_000181"
     CDS             complement(3293..4189)
                     /locus_tag="VXE87_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0841801.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4198..5133)
                     /locus_tag="VXE87_000182"
     CDS             complement(4198..5133)
                     /locus_tag="VXE87_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0841802.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5130..5855)
                     /locus_tag="VXE87_000183"
     CDS             complement(5130..5855)
                     /locus_tag="VXE87_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0841803.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5939..6574)
                     /locus_tag="VXE87_000184"
     CDS             complement(5939..6574)
                     /locus_tag="VXE87_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0841804.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(6576..7403)
                     /locus_tag="VXE87_000185"
     CDS             complement(6576..7403)
                     /locus_tag="VXE87_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0841805.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7425..8351)
                     /locus_tag="VXE87_000186"
                     /pseudo
     CDS             complement(7425..8351)
                     /locus_tag="VXE87_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809127.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            9002..9613
                     /locus_tag="VXE87_000187"
     CDS             9002..9613
                     /locus_tag="VXE87_000187"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0841806.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9658..10386
                     /gene="rlmB"
                     /locus_tag="VXE87_000188"
     CDS             9658..10386
                     /gene="rlmB"
                     /locus_tag="VXE87_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0841807.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10425..11336)
                     /gene="trxB"
                     /locus_tag="VXE87_000189"
     CDS             complement(10425..11336)
                     /gene="trxB"
                     /locus_tag="VXE87_000189"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0841808.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLIVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11402..11626)
                     /locus_tag="VXE87_000190"
     CDS             complement(11402..11626)
                     /locus_tag="VXE87_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0841809.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11704..12447)
                     /locus_tag="VXE87_000191"
     CDS             complement(11704..12447)
                     /locus_tag="VXE87_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0841810.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12447..13247)
                     /locus_tag="VXE87_000192"
     CDS             complement(12447..13247)
                     /locus_tag="VXE87_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0841811.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13405..13761)
                     /locus_tag="VXE87_000193"
     CDS             complement(13405..13761)
                     /locus_tag="VXE87_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0841812.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13774..14286)
                     /locus_tag="VXE87_000194"
     CDS             complement(13774..14286)
                     /locus_tag="VXE87_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0841813.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(14286..14780)
                     /locus_tag="VXE87_000195"
     CDS             complement(14286..14780)
                     /locus_tag="VXE87_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0841814.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14915..15361
                     /locus_tag="VXE87_000196"
     CDS             14915..15361
                     /locus_tag="VXE87_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0841815.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15358..16005
                     /locus_tag="VXE87_000197"
     CDS             15358..16005
                     /locus_tag="VXE87_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0841816.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLVIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(16026..16607)
                     /gene="pdxT"
                     /locus_tag="VXE87_000198"
     CDS             complement(16026..16607)
                     /gene="pdxT"
                     /locus_tag="VXE87_000198"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0841817.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16608..17483)
                     /gene="pdxS"
                     /locus_tag="VXE87_000199"
     CDS             complement(16608..17483)
                     /gene="pdxS"
                     /locus_tag="VXE87_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0841818.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17635..19014)
                     /locus_tag="VXE87_000200"
     CDS             complement(17635..19014)
                     /locus_tag="VXE87_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0841819.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19308..20231
                     /locus_tag="VXE87_000201"
     CDS             19308..20231
                     /locus_tag="VXE87_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0841820.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20291..20896
                     /locus_tag="VXE87_000202"
     CDS             20291..20896
                     /locus_tag="VXE87_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0841821.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20914..22158
                     /locus_tag="VXE87_000203"
     CDS             20914..22158
                     /locus_tag="VXE87_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0841822.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22254..22511)
                     /locus_tag="VXE87_000204"
     CDS             complement(22254..22511)
                     /locus_tag="VXE87_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0841823.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22553..24589)
                     /locus_tag="VXE87_000205"
     CDS             complement(22553..24589)
                     /locus_tag="VXE87_000205"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0841824.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24801..25718)
                     /gene="glyQ"
                     /locus_tag="VXE87_000206"
     CDS             complement(24801..25718)
                     /gene="glyQ"
                     /locus_tag="VXE87_000206"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0841825.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(26086..26847)
                     /locus_tag="VXE87_000207"
     CDS             complement(26086..26847)
                     /locus_tag="VXE87_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0841826.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLS
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(27120..27962)
                     /locus_tag="VXE87_000208"
     CDS             complement(27120..27962)
                     /locus_tag="VXE87_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0841827.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(28076..29467)
                     /locus_tag="VXE87_000209"
     CDS             complement(28076..29467)
                     /locus_tag="VXE87_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0841828.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDVSKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29702..30079)
                     /locus_tag="VXE87_000210"
     CDS             complement(29702..30079)
                     /locus_tag="VXE87_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0841829.1"
                     /translation="MLCQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLASHSFIVK"
     gene            30330..31307
                     /locus_tag="VXE87_000211"
     CDS             30330..31307
                     /locus_tag="VXE87_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0841830.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFADHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            31304..32386
                     /locus_tag="VXE87_000212"
     CDS             31304..32386
                     /locus_tag="VXE87_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0841831.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(32450..33485)
                     /locus_tag="VXE87_000213"
                     /pseudo
     CDS             complement(32450..33485)
                     /locus_tag="VXE87_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(33869..35065)
                     /gene="tuf"
                     /locus_tag="VXE87_000214"
     CDS             complement(33869..35065)
                     /gene="tuf"
                     /locus_tag="VXE87_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0841832.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(35987..36856)
                     /locus_tag="VXE87_000215"
     CDS             complement(35987..36856)
                     /locus_tag="VXE87_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0841833.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(37079..37600)
                     /locus_tag="VXE87_000216"
     CDS             complement(37079..37600)
                     /locus_tag="VXE87_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0841834.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKKDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(37572..38663)
                     /locus_tag="VXE87_000217"
     CDS             complement(37572..38663)
                     /locus_tag="VXE87_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0841835.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEVDTNSASLTGNIVSKGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKSGSQNSNLY"
     gene            complement(38774..39028)
                     /locus_tag="VXE87_000218"
     CDS             complement(38774..39028)
                     /locus_tag="VXE87_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841836.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(39386..39919)
                     /locus_tag="VXE87_000219"
     CDS             complement(39386..39919)
                     /locus_tag="VXE87_000219"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0841837.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(39906..40121)
                     /locus_tag="VXE87_000220"
     CDS             complement(39906..40121)
                     /locus_tag="VXE87_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0841838.1"
                     /translation="MGKERCEQEHIERKKRVVKNRKIPLEELKTFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(40088..40231)
                     /locus_tag="VXE87_000221"
     CDS             complement(40088..40231)
                     /locus_tag="VXE87_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV0841839.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KNT"
     gene            40465..42183
                     /locus_tag="VXE87_000222"
     CDS             40465..42183
                     /locus_tag="VXE87_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0841840.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            42294..42641
                     /locus_tag="VXE87_000223"
     CDS             42294..42641
                     /locus_tag="VXE87_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0841841.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(42919..43755)
                     /locus_tag="VXE87_000224"
     CDS             complement(42919..43755)
                     /locus_tag="VXE87_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0841842.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(43768..44397)
                     /locus_tag="VXE87_000225"
     CDS             complement(43768..44397)
                     /locus_tag="VXE87_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0841843.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(44407..45048)
                     /locus_tag="VXE87_000226"
     CDS             complement(44407..45048)
                     /locus_tag="VXE87_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0841844.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(45194..46423)
                     /locus_tag="VXE87_000227"
     CDS             complement(45194..46423)
                     /locus_tag="VXE87_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0841845.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELANLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(46413..47579)
                     /locus_tag="VXE87_000228"
     CDS             complement(46413..47579)
                     /locus_tag="VXE87_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0841846.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            47723..48736
                     /locus_tag="VXE87_000229"
     CDS             47723..48736
                     /locus_tag="VXE87_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0841847.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(48781..49200)
                     /locus_tag="VXE87_000230"
     CDS             complement(48781..49200)
                     /locus_tag="VXE87_000230"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0841848.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(49211..50617)
                     /gene="atpD"
                     /locus_tag="VXE87_000231"
     CDS             complement(49211..50617)
                     /gene="atpD"
                     /locus_tag="VXE87_000231"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0841849.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(50703..51581)
                     /locus_tag="VXE87_000232"
     CDS             complement(50703..51581)
                     /locus_tag="VXE87_000232"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0841850.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(51597..53102)
                     /locus_tag="VXE87_000233"
     CDS             complement(51597..53102)
                     /locus_tag="VXE87_000233"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0841851.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(53117..53653)
                     /locus_tag="VXE87_000234"
     CDS             complement(53117..53653)
                     /locus_tag="VXE87_000234"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0841852.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(53653..54147)
                     /gene="atpF"
                     /locus_tag="VXE87_000235"
     CDS             complement(53653..54147)
                     /gene="atpF"
                     /locus_tag="VXE87_000235"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0841853.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(54161..54877)
                     /gene="atpB"
                     /locus_tag="VXE87_000236"
     CDS             complement(54161..54877)
                     /gene="atpB"
                     /locus_tag="VXE87_000236"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0841854.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(54912..55112)
                     /locus_tag="VXE87_000237"
     CDS             complement(54912..55112)
                     /locus_tag="VXE87_000237"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0841855.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(55187..56140)
                     /locus_tag="VXE87_000238"
                     /pseudo
     CDS             complement(55187..56140)
                     /locus_tag="VXE87_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155340.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(56608..57006)
                     /locus_tag="VXE87_000239"
     CDS             complement(56608..57006)
                     /locus_tag="VXE87_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0841856.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            57134..57211
                     /locus_tag="VXE87_000240"
                     /pseudo
     CDS             57134..57211
                     /locus_tag="VXE87_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(57424..57906)
                     /gene="greA"
                     /locus_tag="VXE87_000241"
     CDS             complement(57424..57906)
                     /gene="greA"
                     /locus_tag="VXE87_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0841857.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(57977..59632)
                     /gene="mltG"
                     /locus_tag="VXE87_000242"
     CDS             complement(57977..59632)
                     /gene="mltG"
                     /locus_tag="VXE87_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0841858.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVSTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(59713..60207)
                     /locus_tag="VXE87_000243"
     CDS             complement(59713..60207)
                     /locus_tag="VXE87_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0841859.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(60204..60668)
                     /locus_tag="VXE87_000244"
     CDS             complement(60204..60668)
                     /locus_tag="VXE87_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0841860.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(60678..62012)
                     /locus_tag="VXE87_000245"
     CDS             complement(60678..62012)
                     /locus_tag="VXE87_000245"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0841861.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(62023..62640)
                     /locus_tag="VXE87_000246"
     CDS             complement(62023..62640)
                     /locus_tag="VXE87_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0841862.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(62688..65786)
                     /locus_tag="VXE87_000247"
     CDS             complement(62688..65786)
                     /locus_tag="VXE87_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0841863.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINRQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADTNLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADSHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(65879..67045)
                     /locus_tag="VXE87_000248"
     CDS             complement(65879..67045)
                     /locus_tag="VXE87_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0841864.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNESKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(67053..68147)
                     /locus_tag="VXE87_000249"
     CDS             complement(67053..68147)
                     /locus_tag="VXE87_000249"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0841865.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVFAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(68305..68850)
                     /locus_tag="VXE87_000250"
     CDS             complement(68305..68850)
                     /locus_tag="VXE87_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0841866.1"
                     /translation="MEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLV
                     TDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEILI
                     FDESTANLDAYSEYAIISILYSALKEKTVVIIAHRLSTVKDVDCIFFLEERKITGSGT
                     HKELLENHERYARFVQEQMIE"
     gene            complement(68886..69986)
                     /locus_tag="VXE87_000251"
     CDS             complement(68886..69986)
                     /locus_tag="VXE87_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841867.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALDNLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENR
                     PVLKDITCSIFKGQKLLLLDHLDQENQRLCVC"
     gene            complement(70158..71708)
                     /locus_tag="VXE87_000252"
     CDS             complement(70158..71708)
                     /locus_tag="VXE87_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001158287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HEV0841868.1"
                     /translation="MQDSVAGLDDYITGKTSDFSTVGVKALDDQTVQYTLVKPELYWN
                     SKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWD
                     AKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSM
                     QNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSE
                     GKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINFADGQDPYYNPEK
                     AKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDI
                     QQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFNTNSGGVLQNLGLE
                     PGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYADIQAWLIDSSLVLPSVSRGGT
                     PSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESNKKAQ
                     EELAKHVK"
BASE COUNT        21076 a        15824 c        13010 g        21804 t
ORIGIN      
        1 tcgatttcta acaatgtttt agaagcagag gtgtactatt ctagtttcaa tctactatat
       61 ttttggagtg atagaaaagc ctttcatcag ccaatctact tgttcaggtg cgagagcttt
      121 gacatccttt tctgtactgg gccaagtcag tctgccgttc tcaaagcgtt tatatagtag
      181 ccaaaatcct tgaccatccc agtaaagggc tttaaagcgg tctttacgtc caccacaaaa
      241 gagaaaaact tgaccggaga aaggatccaa ttcaaagtgg gttttaacca gataagccag
      301 tgaatcgatt ccttgtctca tatcagtctt cccacacacg agatagacct gccctaggct
      361 agatagatga attgtcatag agcaacacct tatccaaaag ctgttctacc atttcgagat
      421 tgagagattg aaaaaaactt acttcaagct tgccaatacg aattttaagc agaatatcat
      481 ttctcttttt agaatcaaaa ggacgagatt gtggaatctc tacaggaaca ataggttgtg
      541 gcattaaaat atcctccaat agttttactt tactaatagt atacaggagg aactccatga
      601 atgatagata ccttgttatg acgcgcttac tatattagaa agttggctct ctaattaaat
      661 taattctcat tatatatatc aaaagaccgc agtttgaaaa ctacggtcta attttttgtc
      721 caaatgtaaa tcacttggaa ctattattca atttattctt tttagtaaat gttcccgttt
      781 taatcccagt tacagttttt aatcctctgt aaccgttgat tttacaaagc ttttaatttt
      841 tttgcgatta ctcccactca actgttgcag gtggtttact tgtaatatcg tagacgatac
      901 ggttaacatg atccacttca tttacgatac gcactgagat tttttgaagt acttcccatg
      961 gaattttggc aaaatcagca gtcataccat cgatagaagt gatagcacgg attgcaatcg
     1021 tgtagtcata cgtacgaccg tcacccataa caccgactga acgaacgcct gtgttaacag
     1081 tgaagtattg ccaaatatcg cggtcaagtc cagctttagc gatttcttca cgaagaatag
     1141 cgtctgattc acgaacggtt tcaagtttct cttcagtgat ttcacccatg acacggatag
     1201 caagtcctgg tcctgggaat ggttggcgcc atacgatatg gtctggcata ccaagctctg
     1261 taccaagagc acgaacttca tccttgtaaa gagtattgag tggttcaatc aattcaaact
     1321 gcatatcttc tggaagacca cccacgttgt ggtgtgactt gatagtttga gctgtatccg
     1381 taccagactc gataacatct gtatataaag taccttgagc aaggaatttc acatctttga
     1441 gcttgcttgc ttcgtcatcg aatacataga caaactcgtt accaatgatt ttacgttttt
     1501 gttcaggatc agaaacgcca gcaagtttgt caaggaaacg tttagcagcg tctgctttga
     1561 cgatattcaa accaaactta ccaccgagca tgtccataac ttgatcagct tcgcctttac
     1621 gaagaagacc gtggtctacg aagatacaga tcaattgatc gccaatcgct ttttggagaa
     1681 gaaccccaac gacagatgag tcaacaccac ctgatagacc aagaaggaca cgtttatcac
     1741 cgacggtttc acgaattttt ttgatctgca tgtcaatgaa attatccatt gaccagtcac
     1801 ctttagcctt acaaatgtta agggcaaagt tacgaaggat atcatttccg tatacagaat
     1861 gacgaacttc tgggtggaat tggataccgt aaatgtgttt atctgggttt tcgatggctg
     1921 cgtatgggca gtcagctgat gtacctgtac gaacaaagtc agcaggaatc tcagtaaccg
     1981 catcaccatg gctcatcaaa acagtctgtt catcaggtgt tgattcaaaa agcgctgatg
     2041 gtgtgtgagt tagggttgat tgaccgtatt cacgatttcc agcatcacct gcaggaacaa
     2101 cttttcctcc aagtttatgg gtcaataact gcataccata acagattccc aaaattggaa
     2161 ttccgagttc gaagatttct gggtcaatat caaatgaacc atcttcatat acagaatttg
     2221 gaccacctga tagaataatt cctacaggat tgacttcacg aacttcagca gctgaaattt
     2281 tatggctttt tagttctgaa aaaacaccaa tctcacggat acggcgtgaa atcagctggt
     2341 tgtactggct accatagtcc aatacgatga ttttttctac atcttgcaaa tcagttgaaa
     2401 tgttgctcat ctttttcctt tctcaaaaga aatatctttt ctcaatattc tatcacaaat
     2461 aagggcgaat taccaactaa acaaggcgaa gtttgacttt ttctagttta ttggggtaca
     2521 atagagaaaa gatagaaatg aagtgaaaaa tatgctacct gcttatatga aaatccatga
     2581 tcagataaaa aaggatattg acgagcaccg ttgggctatt ggtgagaggc ttcccagtga
     2641 aagagattta gctgagcagt ttgcggtcag tcgcatgacc ctccgccaag ccgtatctct
     2701 attagtcgaa gaaggcgtct tagagcgccg tgtaggaagc ggcacctttg tttccagtac
     2761 tcgagtacaa gaaaagatgc gagggacaac cagttttact gaaattgtca aatcccaagg
     2821 taaagttccc tctagccagc tcatttccta caaaaaaacc attcccaatg agcaagaagt
     2881 tgccaagcta ggaatttttc caacggacaa tattatccga atggagcggg tccgctatgc
     2941 cgaccaagtt cccctagttt atgaagttgc ttctattcct gaaaaattca ttaaggactt
     3001 taaaaaagaa gaaatcacca gtcatttctt ccaaaccttg caaaaacatg gctatcgtat
     3061 cggtaaatcc caacagacca tctatgctcg ccttgctaaa gaaaagattg cccactattt
     3121 ggaagttgaa aaaggacatg ctattcttgg attgacccag atttcctacc tagaagatgg
     3181 tactgctttt gaatacgtaa aaagtcaata tgtaggcgaa cgctttgaat tttatcttga
     3241 aaataattag attaccacgc aaaaactctc tgtcacggac aaagagtctt ttttattttt
     3301 ctaagaataa atctttcaaa gaaatcaaag ttacagcaaa caatatcatt gccataccaa
     3361 gaaaatcaat gggataaaat tgttcattca ttattaagaa ggcaaagaaa atcgccgata
     3421 ttggctcaat tgaagccaac aagcttgact tgaccggtcc tatcagactg gctcctttaa
     3481 ggaaagctgt ataggcaaag acagtcccga taaggataat gcctgcaaac gcaaggagaa
     3541 aatcaagact agtcgggata tcggcctgta gaacccctgt aaaaggaagg gcgaccaaac
     3601 ctgctatgac cattcccaca ccaatgacca agctgctccc ccacttttta atcaaggcta
     3661 tgggtaaaat gatatacaga gcataagtca aggcagaaaa gagaccccag aacagaccag
     3721 caggtgtcat ggataactgg tccaactgcc catgtgttgc gatcaggaag gttcctccga
     3781 tggcgaatat gatggaaact atctctccca gtgtcggtgc caccctatcc ttgatacagc
     3841 tataaattaa aattccgaca ggacaaacat actgaagcac cgtcgctgtt cccgcattgg
     3901 tctcctgaat agcagacaga taggcgaatt ggttgagaaa aagaccaatc agagcaaaaa
     3961 taagaagaga cagcaaactc tttctatcct ttaaaaagac cagtatttta tcctttgcag
     4021 tagcataagc caagagcatg agaattccac cagcgattaa aagacgcaag ttagtcaaga
     4081 ccagagccga aattccgtgt gccattaggt attggccact cgttcctgac aacccccaag
     4141 caataccagc cacaactgtt agtaaagtcc cttttaaact atttgacatg tctctcctta
     4201 ctcttctttg cgaatcaagt tcatcacttg attgcggtct aatatccatt gagctctctc
     4261 gtccttttca taggtacgat tcgataggaa aatagtggct tcttgcttct gacgattcca
     4321 catgataaag gtacctgtat agcccgtatg gtctagccaa tctccttcca aattccatgc
     4381 taaagaacgt tccttgtcat ccaaaggaga aaaattttga tttaagtctc ttgcaaaatc
     4441 atctgctaaa tagtgttcta aaaagatttg taaatccttt atagtcgaaa ataaaccagc
     4501 actcccagca tgtctaccca ggagacgagc cttgggatca tgcactatgc ctgcctctac
     4561 acctctaact gttggaacag caagctcaac tggcccaaac ttggtttccg tcattcccca
     4621 aggtttccag acttgatcct ttaaaatcac atccaaatct tgattaaaaa ttctttccaa
     4681 aataaagccc aacagcaaaa aatggacatc cgaataaaga aaggctggct gacttcgtct
     4741 gttgagatga aacatcgctt cctttaattc aggggctgtt aaaagatcac gattaggaat
     4801 aaaaggatca aggtctgttg catgagtcaa gagctggcga atagtgatgt ctggataatc
     4861 actctcaggt aaaaaatcta ttaccagtct atcaatatct aattgaccta tttcccacaa
     4921 gaaggtacaa actgtgccaa ccccaacaac cttgctgaca ctagctaggt cataaactag
     4981 tcctgcctca gtctgcaagc catgctctgg gtcactctgg cctaaataga actctgtcca
     5041 ttgattgtcc ttaaaatacg caaaagaggc tccgggataa atccctgcct cgatttgttc
     5101 ttctattttt ttaataatct tggtccactt catacttctt caaaccacaa ttcaacatta
     5161 tttctatctt taccaaggaa gaatttttca gacttaggaa taaaatattc agtagactca
     5221 aacttctggc gaagacttgc tatgtctaat tcattgacca agaacttgag catagataag
     5281 tcccaggtaa ccgtattgtc cacagtcaaa tcctgcccct gagctggaat aaaatcaagg
     5341 gatgccccaa tttcagatga ttccaagaaa ctttcgatat cagttgggag atgtaattcc
     5401 atagaaatct caaatttact taaagaaatt gatgccaaat ctgtttgaaa ttcaggcttt
     5461 tctcctactt ctactagact tgctatgtca tcttccgcat gaatcaaaat caaatcatct
     5521 tctggtgaga aaatttcaaa agcgtagcca ttttgacctt tatataatcg atgaatcgaa
     5581 tctgttttag ataagattcc ttcaatttct aagggatttt ccaccttgac aatcaatcta
     5641 gctagttttt ttcttccctc taccttacga gtacgcatac tgggagcttc ttctaaaacc
     5701 agcttttcaa gacccgtttg gtcacctagt gacagaaagg ccgattcttc taacaaggcc
     5761 ttcattccaa gggtttcaat ataaaatgtt tcatttaatt ttctattatt agcttttaaa
     5821 gtaggaataa tccgtacaat ctgatttaca ttcataaatt cctccgtcac tttttatttt
     5881 aaaggatttt agaatttttt acaagatatt atgctcaaat ttaacattat ttagctattt
     5941 agtaaagata gtctttcaag gattttgaca aagcctgata accagcaata ctgaggtgca
     6001 gtccatcagt tgtatattct tttttgagtt ggcctgcttg gtctgtcaaa caatcaaata
     6061 ctggcacaaa ttccacctgc atataggcag atgcaagctc ttgataggct tgattccagt
     6121 tctgaatttt ttcattcgag cggatataga ctgcctgctg gtactcctct ctctcattga
     6181 caggcaaaat ggaaagcaat ttaatctctg tcaatggata atcgcgagca acggattgaa
     6241 tgatagcttc gagattattg agagcctcat tcacaggaac atcctttccg atatcatttg
     6301 tcccaatcag aagaaaaatt ttatctactg ctccaccata tagatgagca tcaaggttct
     6361 ctagtaacag tcctgtctga tagccacgaa ttcctcgatt gacaatcgtc tttgaagtcc
     6421 caaatagctc ctgtagagga taatactcga caatggaatc cccaataaaa agaatgtttg
     6481 gttctacaac agaaatgtga tttaggtgac gatacttagt ttgaattttt tcttgttcct
     6541 ttaggagcca attttctaat aactgtactg ccacttcatt ctcctttttc taaccagttt
     6601 tccaagactt gataaactcc tccttggctg ttggctggtg ctagagcagt cgccacagct
     6661 ttggctttct catcagcatt ttccatcgca taggcaattc cagccatttc aagcatttca
     6721 acatcatttt cactatcacc aaaagccatg atttcttggg atttcaagtc ccagcgcttg
     6781 agtaattcct ccaagcccca tgctttatga atcccagctt ggaggatatc aatgcaacca
     6841 tagccactgg atacagctcg gacacggcca tcaaagagag cattgatttc ttccaaaacc
     6901 gaactcaaac gttcctcacc aacaaccatg ctcatcttga gcacaccacc aaagaggtca
     6961 gatgttaatt catccacaaa ttgcatccgt tggtagaatt tttcaatcat ttctggagtc
     7021 ataaaacttt caagatctgt aaaaatcgta ccttccttga caaaatcacc cttcatcccc
     7081 gttacaacaa actggtcctg acacgctcga cccttgaaat gagtcaaagc cttgttgaca
     7141 atggcgtcat cccatgtctg agcctgaatc aattcattgt tttcaaaaat acgagcgcca
     7201 ttagcaacaa ccagaaccac tcgatccacc aagggactca gtagttgtct catgcggtga
     7261 atttcattgc ccgtcgcaat gacaaaacga atgccccttt gatccaactg atctaaaatc
     7321 ttttccaatc gtgggagatc aagctgacct ctagcatcca gcaaggtccc atccatatct
     7381 gtcgcaatta ccttaatcat catttacttt cctctggatt caagctaata ccacttcaat
     7441 cccacatgtt cattcatttc tttataggct gtatcaattc gttccttagt cgcttcatct
     7501 aactggtcac gatgactgcc atcctctata aaatcttcca aaatataagt ttggtaatga
     7561 tacaagggat atccttctgg tgaaaaggtt ccctttggtg ttcgattgac ccaagtagga
     7621 tgagctttag ctgttccgat agttgttttt ccatccttct tcttgatggt gacatccatg
     7681 agaacaccac gttcagtcca cttagcattc tcttcatctc ccatagattc aattcgttga
     7741 ttggaaatga agttccccat ttaatagata atgagtttct tatctccatc tttttcaacc
     7801 gtttcagatg gttcaacaac gtgaggatgc cctccaaaga taatatccgc tcccaaatcg
     7861 atcatcttgt gataaagagc tttttgttct tcagttggtt ccaatcgata ctcaacaccc
     7921 atctgaagca tgataatggt gatatctgct tccttctctg cccgttcaat ttcaaccttt
     7981 atcttatctt cgtttaaata tgaaagataa cgattatagt cttcctgaga aatatactgc
     8041 tcaattccat tgaaaccata ggaataggct aacaatgcaa ccttgatacc attcacttcc
     8101 ttaatgacca gcggagcctg atcacgtggt tcgtgcgtat aaactccgat tggagtgatt
     8161 ccagctttct caataatatc ggccgttgaa ataactccct caatttgcga atccaaaata
     8221 tgattatgag ctaaatccag cacatgataa cctgcctcct taatagcatc cataacttca
     8281 acaggagcat taaagagaag ataacccgct aaataatgat ccttattaat ggttccttca
     8341 aaatcaccaa tagctaaatc tgctgcttag tccccttgct tgagccaagg agtcacatac
     8401 tcaaaatttt catgaaagtc ataggtaccg tcttcttttt tagctgaaaa gaaaagtcca
     8461 tcgtggtaga gcaaatcccc gtgggccata attctggcag ttttttcctc ttcctactcc
     8521 tgagactttt gcttagtccc ctcttgagaa atagtatctc gtttttgact agtcaaggga
     8581 ttccttggaa gctttcaaac aacaagacca agcccattga taaaccaact gctagcaaga
     8641 gtatcgccac aaatccctta ttgctccact tgcgataact cctaaaaagt ttaccaagcc
     8701 cttcataaaa cgaaaagcta aaccaccctg atttcgattt tgtcttcttt gtatcttcgt
     8761 tctccctact ttcttatgca agccttttct ttttattata tcacagataa gtatttcttt
     8821 cacaattgaa ttgaacttcc catctatttt ctataaatcc taaatgccat aatgctttca
     8881 attcttgtca ttttgtgata tcatgtagag gaaatgaact aatccacagt ggcttattcc
     8941 aagtatacca cttgggcttt ggcagtagct aactgcacta aacataatat aaggagagaa
     9001 aatgtctgca atagaacgta ttacaaaagc tgctcactta attgatatga acgatattat
     9061 ccgtgaaggg aatcctactc tacgcacggt tgctgaggaa gtcactttcc ccctatctga
     9121 ccaggaaatc atcctaggcg aaaagatgat gcaattcctt aaacattccc aagatcctgt
     9181 catggctgaa aaaatgggac tccgcggtgg tgttggactg gctgctcccc agttagatat
     9241 ctcaaaacgc attatcgctg ttttggtacc taatattgtt gaagaaggcg aaactccaca
     9301 ggaagcctac gatttggaag ccattatgta caatccaaaa atcgtctctc actctgttca
     9361 agatgctgct cttggcgaag gagaaggttg cctgtctgtt gaccgtaacg tgcctggcta
     9421 tgttgttcgc catgcccgcg ttactgttga ctactttgac aaagatggag aaaaacaccg
     9481 tatcaaactc aaaggctaca actccattgt tgttcagcat gaaattgacc acattaacgg
     9541 tatcatgttt tacgatcgca tcaatgaaaa agacccattt gcagttaaag atggtttact
     9601 gattcttgaa taaagaaaat cccgttgcaa gacggggttt tgtgttataa tagaggcatg
     9661 aaaacaaatg atattgtcta tggtgtccac gccgttaccg aagctctcct tgcaaataca
     9721 ggaaacaaac tctacctcca agaagatctc cgaggtaaga atgttgagaa agtcaaggaa
     9781 ctagctacag aaaagaaggt gtccatttct tggacatcaa aaaaatctct ctctgagatg
     9841 actgaaggtg ctgttcatca aggttttgtt ctacgagtgt ctgaatttgc ctatagcgag
     9901 ctagattaca tccttgcaaa aacacgccaa gaagaaaatc cacttctatt gattctagat
     9961 ggtctaaccg atccccataa tctgggttct atcttgcgaa cagccgatgc gaccaatgtt
    10021 tcaggtgtca tcattcccaa gcaccgtgct gtcggagtaa ctcctgtcgt tgccaaaaca
    10081 gccacaggtg ctattgaaca cgttccaatt gcccgagtga caaacctcag tcaaacctta
    10141 gataaactca aggatgaagg cttctggacc tttggaacgg atatgaacgg tactccttgc
    10201 cacaagtgga atacaaaagg gaaaatcgcc ctcatcattg gaaatgaagg aaaaggtatc
    10261 tctagcaaca tcaaaaaaca agtcgatgag atgattacca ttccgatgaa tggacatgtt
    10321 caaagcctta atgccagtgt tgctgcggcc attctcatgt acgaagtttt ccgaaataga
    10381 ctataaaaaa gtttccagtc atctgattgg aaactttttt atgattaact atgttctgtg
    10441 ataaacttgt aggcttcttg accagcgata gctccatctc caactgctgt tgttacttgg
    10501 cgaaggtctt tcaagcgaac atctccaact gcaaagatac cgtcgactgc agtcttcatg
    10561 tggctatctg tcacaatcca gcctgcctga tcttggatat tcaattcttt aacaaaatcg
    10621 ctaagagggt ccaaaccaac atagataaag acaccaccga aggcttgttc tgtcacttga
    10681 cctgttttca cattttcaaa tacgactgat tctactcggt tttcaccctt gatttccctt
    10741 actacagaat cccagataaa gctgattttt tcattcgcaa aggcgcgatc ttgtaaaacc
    10801 ttttgggcac gaagttggtc acgacggtga acaatggtaa cagtcttagc aaaacgagtc
    10861 aagaagaggg cttcttcaac agctgaatct ccaccaccaa ctatcaataa atcttggtca
    10921 cggaagaaag caccatcaca cacagcacag taagaaacac cacgactgtt cagttcttct
    10981 tctccaggca ctcccaaagg acggtgttta gaaccagttg ctacgataac tgtacgtgtt
    11041 tcatatgttt ggtcatcagt catcactttc ttaaaatcac catggtcttc gacattttca
    11101 acataaccat aaatgtgctc aacaccaaga ttttcaagtg gttcaaacat cttttcagcc
    11161 aattcaggtc cactaatatt agcgtatcct gggtaatttt cgatatcaga tgtattattc
    11221 atctgaccac ctggcagacc accttcaatc aaagctactt ttagattgct tcgagcagca
    11281 tacaaggccg cagtcatccc tgcaggtcca gcaccgataa taatagtatc gtacatatag
    11341 attccttctt tcttgttgta actatcttta ttctaactct ttcttgtcaa tcacgcaagg
    11401 attatgcctt gaaaacaaga attaaactca taaccgcaaa ggataatact gggacaacca
    11461 agactccaat cataatcata tcatagagat gggcttggcg agccttggct gtcttatcaa
    11521 ctcccgacat ggctctcaga ccaatccaaa tccctaaaaa aatcagaaca aggatggtgg
    11581 tcaatatcaa actctcgaaa tataaagaaa atagttgcag tagcatgatt tctctcattt
    11641 ctatcttttt taaagagtaa actcagctag tccaactaac tgagttttcc tttatctatt
    11701 atatcaaata taagtccgtt tgtaactagc gaagaattct tttgtccgct cttctttagg
    11761 ggtgtggata atctcatccg gagttccaga ctcgatgatt ttccccttat ctaagaagag
    11821 aatcttatcc gcaacttggg ctacaaagga catgtcatga ctgaccaaaa tcatggtctg
    11881 acctgactta gcagcatctg caatagactt ttctacttca ccgaccaatt ctgggtcaag
    11941 ggctgaagtt ggttcgtcta agagcaaaac atctggtttc atagcaagcg cacgcgctag
    12001 ggcaacccgt tgcttctgtc cacctgataa atggcgagga taatggtttt cacggtccga
    12061 aagcccaacc ttagccaact cttccttggc aatcttagtc gcttcttggt cagataattt
    12121 cttgacaaca accaagcctt ctttcacatt atcaagtgct gttcggcgtt caaacaaatt
    12181 aaactgttgg aaaaccatag acaacttacg gcgtagggca aggatttctt cttgagtgat
    12241 tttagaaaaa tcaactgaaa aaccatcaat ctgaatagag ccactgtcag gtgtttcaag
    12301 ataattgaga ctgcgaagaa aggttgattt tccagctcct gaagaaccaa tcaaggctac
    12361 aacttcccct ttttgaatat ccaagtccag atgatccaag acagtctgtc ctgaaaagga
    12421 tttgcttaaa ttcgaaatct taatcattaa cgaaggtctc ctttcacatc tgtttgcact
    12481 gtatcaggtg cagaaatagc catttttctc tcgatgaaac gaccgaggct ttcaattccg
    12541 atattgacta cccaataaac aagggcaacg gagatgaagc gttcaaaata gcgataatca
    12601 gctccaccta gaatctgagc ttgggcaaag acttccacaa cacccgcact aaaagctaga
    12661 gatgttccct tggtcaaacc gatgagggaa ttaatcaagg ttggagtagc taccaccgct
    12721 gcattaggaa taatcactcg tcgataaact tgcgctcggg tcatacccag actgcgtgcc
    12781 gcctcaatct caccaggatt aactgagaga atggctgcac gaatggtttc actagcataa
    12841 gctgcctcat taaaggcaaa agcgacaatc gcaaaagctg cagctggaat cgcattgata
    12901 ttgagaccag ttccccattg ctgattgagg gctttcaaag ccaaagggat tccgtagtag
    12961 gtcaacatga gttgcaccaa aatcggtgtc ccttttaaga aactaacaaa gaaggcctgc
    13021 aagggatata aaatcttgac acgattgatc ttcacaatgg caaaaagaag cgccaaaacc
    13081 aagccaaaaa gggcaccacc aattgtcaac ataattgttg ttggaagttg ttggacaatt
    13141 ctagggattc catcaaagac cgaacgtagg ctaaacagct tgccatccgg aatcaattgc
    13201 atcaagtttt ggtaccaatc tgatgctaaa atcgttgtaa cattcataaa aacatcctct
    13261 tctgataatg attcattcta ccatgcttct gccgtcaatg aaattatttg ctacggtcag
    13321 atacagactt tgtctaccta ctagtttatc atactttgaa acagggaagt tatatatttt
    13381 atctatcaaa gagatagata aaaactattt cagtcccagt tcttcataag attttcgata
    13441 accgatttgc ttaacagttc cattttctac taaaatgggc cgttttaaca acataccgtc
    13501 acttgctagc aactcagccg cttcttggtt tgacaaactt cctaccttat cttttagccc
    13561 taattcacgg tatttgatac cactggtgtt gaaaaattgc ttcaattcaa atcctgaggt
    13621 ttctagccaa ttcaaaatga cttcttggct aggtgtttct tccacgatat ggacggcttt
    13681 atagtccaca cctaattgat ttaattcttg ttttgctttt ttacaagttg aacatttggg
    13741 gtattcgata aattctaaca tgtgcttctc cttctatttg tttatatctt taaaatctac
    13801 gccttcatgc tccaagagcc aagctttctt ttccactcct gcagcatagc ctgtcagacg
    13861 cttgcctgct cccaacacac gatgacaagg tactaggata gaccaaggat tgcgtcccac
    13921 tgctccacca attgcttgag cagaagccac ttgcaggtct tgagcaattt gtccataggt
    13981 cactgtctga ccataaggaa tgccctgtaa atagtcccaa actctctttt caaaattcgt
    14041 tccgattggc gccaagagca agttggataa atcctgaggc ttgcctttaa agtaatcatc
    14101 taagcaagca ataactgggt ctaaaatagg atgactaaca acttcttcta tcgtttcatc
    14161 tcctagtccc ctctcaaaat gcttctgctc ctgaacccaa attccataca aataatggtc
    14221 atcagctaca agtgatagaa taccaattgg tgaggagtag agtattttta catacttctt
    14281 ttgcattatt tctttaattt ttgataggcc aagcgttcgc catctactgg caccttacca
    14341 acttgtttaa aaccaagttt ttcaaaaata tgttgcataa ccttgttttc agcatgcgta
    14401 tctgagcgaa aatcaagata atcaaaacct tcaatcaagc cctctaagaa ggtttgagca
    14461 actccttttc cctgcacatc tgctgccaca gcaatacggt gaaagactag atactctgac
    14521 tctccagctt gccagtttcc ctcataaata gcttcatagg cctcctctgg actcttggtc
    14581 acagcagcat aggctagcag ttctccctct tccaaggcta cgtaggcttg ccctgagatg
    14641 atatcatcga taataacatc tgcatttgga tagccatttt gccactggtc actaccagca
    14701 tctgctaaac attttttggc atcctccatc acctgcatga tggcatctac ttcatttgga
    14761 aaagctaaac gaatttccat cttttttcct catttctgac tagtttctcc catcatagca
    14821 taatttaagt atttctacaa gcagttaaaa cttgactttg tgtttttgtt attttataat
    14881 ctagttatca aaactatata aaaaggagtt gaaaatgaaa actacctttt cctacccaaa
    14941 atgggcagaa attccaaaca ttgacctcta tctggaccag gttttgctct atgtcaatca
    15001 ggtctgcgcc cctatctctc ctaataaaga caagggccta acagcatcta tggtcaacaa
    15061 ttatgtgaaa aatggttacc tgacaaagcc tgacaaaaaa aaataccaac gccaacagat
    15121 tgcccgtttg attgctatca caaccctcaa gtctgtattt tctattcaag aaatagccca
    15181 gacacttaac actctacaaa ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga
    15241 ctatatgaac caaggaattg acccagctaa ccctattatc caaaccagct gccaaaccgt
    15301 taaactctat catcaaactc tagacttaat cgatcatact caagaggagg taatccaatg
    15361 aacactagtc ttaaactcag caaacaactc agttttggag aggagattgc taatagcgtg
    15421 acccatgctg tgggtgcagt catcatgctt atcttgctgc ctatttcatc catctatagt
    15481 tatgaagcac acggattttt atcctctatc ggcgtttcca ttttcgtcat cagtctcttt
    15541 ctcatgttcc tatcatccac catttatcac tctatggcct atggttcgac ccacaaatat
    15601 gttttgcgaa tcattgacca ttctatgatt tacgttgcca ttgccggctc atacacgccc
    15661 gttgtcttga ccttgatgaa taactggttt ggctatctga ttattgtcat ccaatgggga
    15721 acgaccatct ttggtattct ctataaaatc tttgctaaaa aggtcaatga gaaatttagc
    15781 cttgctcttt acctgattat gggctggttg gttctggtta tcattcctgc cattatcagt
    15841 caaacgacac ccgttttctg gagtctcatg gtaactggcg gactctgtta tacagttgga
    15901 gctggatttt atgccaagaa aaaaccttat ttccacatga tttggcatct ctttatccta
    15961 gctgcgtccg cacttcaata catcgctatt gtttattaca tgtaaaaaag ttgagaaatt
    16021 caatctcaac ttttttcttt acacatattg ataaagtact ggtgcaagcg cacatcatca
    16081 gtcaattctg gatgaaaaga acttaccaac atattttttt cttgggctgc aacaatttga
    16141 ttgttcactg ttgctaaaat ttctacaccc tcaccaacac tactgataat cggaccacgg
    16201 ataaaggtca ttggaatctt gccaactccc ttacattctg cttccgtgta gaaacttcct
    16261 aattggcgcc cataagcatt acgctcgacc accatatcca tagttcctag atgactctct
    16321 ttctgagaag tgatttcctt agccagcaaa attaagcccg cacaggtccc aaacactggt
    16381 aagccagata gaatggcttc tcggatggga agtagcatgt tctggtcacg taagagcttg
    16441 cccatggttg tagactcacc accaggcaaa atcaaacccg acaagtcact ctgatcttgc
    16501 tgaaaatcat ctagatttct gagttctaca ctctcgacac ctaattgatc tagcactttt
    16561 gcatgttctg caaaggcccc ttgcaaggcc aatattccga ttttcatcta ttttcctcgt
    16621 tcagccatga gaatttggat ttcattttca ttaataccaa ccatggcttc tcctaaatct
    16681 tcagagattt gagctaggat ttgaggatta cggaagttag tcacagcctt aacaatggca
    16741 ctcgctcgtt taacaggatc tcctgacttg aaaatacctg aaccgacaaa gaccccctct
    16801 gcccctaatt gcatcattaa cgcagcatct gctggcgttg caacacctcc agcagcgaaa
    16861 tttacaactg gcaattttcc atgttcatga acatattgga ccaattctac agggacttgc
    16921 aaatccttgg cagcaacata aagctcgtcc tcacgtaagt tttgaatgcg gcgaatttcc
    16981 tgattcatca tacgcatatg acgaacagct tggacgatat cccctgtccc tggttctcct
    17041 ttggtacgaa tcatggaagc accttcagcg atacgacgca aggcttcacc caaatcctta
    17101 gcaccacaga caaaaggaac ttggaattct ttcttgtcca catggaaacg gtcatcagct
    17161 ggagatagaa cttcactctc gtcgatataa tcaatttcaa tagcctctaa aatctgagct
    17221 tcaacaaaat gcccgattct gaccttagcc attactggaa tactaaccgc ttcttggatt
    17281 tccttaatca tctttgggtc gctcatgcgg gaaactcctc cagctgcacg aatatcagcc
    17341 ggaattcgtt ccaaggccat cacagctgcc gcaccagcag cttctgcgat acgagcctgt
    17401 tcaggattct gcacatccat aataacacca cccttgagca tctgtgccaa gtttttattt
    17461 agttcataac gattttcagt catttgtttt atcctcatca tttgtattgg tagctacctt
    17521 ttcattttaa gtcagaacag aatgaagcac aagataaaaa aactataatt gtatggggac
    17581 agattggcta aaaattatct gaccttaact taaggccaga tagctcattc atttctattt
    17641 ttcagccgta agggcagcca ttgtgatgta gttgtatggt ttgttgaagt gtggcaagaa
    17701 gaagaggtct gtcaatgcca atttatcaat tgtcacatgc tcttggatag caagtgagaa
    17761 catgtggatt cccatgctaa ttgcaatatc atgtgaaacc atttgggcac caagaatttc
    17821 acggctatct ttgtcaaaga caatcttaat tgctacttca tggttgtcat gtttcatgaa
    17881 ttctggtttt tgaagatcgt taaagcctgt ttcagttgcg ttgtaaccag cagctttcgc
    17941 tttttcaaga gtcaaaccag ttgaaaccat gtgaagaccg tagattgaga taccatttga
    18001 accttgaaca ccgattcctt ccaattcatg tccacaagca ttgtaggcac caacgatacc
    18061 agtgcgaaca gcatttgaag caagagcgat atagcttgta tctttacgag cattgtcata
    18121 aacagtcgca cagtcaccaa cagcgtaaac gcctgggata gatgtttctt gtttcttgtc
    18181 tacaaggaag gcaccgttgc ggaagagttc gatcttacca tctgcaaggg ctgtgtttgg
    18241 acggaaacca actgcaagga taaccatatc cacgtcaaag ctttctttgt cagtaatcaa
    18301 gcgttcaact ttaccgtcac cttcgattgc tttaacagtt tgacctagag ccaagcggat
    18361 gttgtgatct tccaagttct tcgccatcat ttgtgtgaag tctttgtcat agtaaccgtt
    18421 caagacagta tcaacgatat caacaaggac aacttctttt ccaagacgtt caaaggcttc
    18481 agcaagttca acaccgatgt aaccaccacc aacaacggcg atacggtcga ggtgttggct
    18541 cttgtcagaa agtttattga taacttcttc agcattttgg tacaatttca cgaattgtac
    18601 gttttcaaga gttgctttaa attcgcggtt tcctttaaca atttcaacac cttcgattgg
    18661 tggcaagatt ggtgtagaac ctgtagcgaa aatcaatttt tcgtatgatt ctttgtgctc
    18721 ttttccttca acttccgctg taactacttt gttatcatag tcgattgaaa gaacaggtga
    18781 gttcatgtaa actttagcac ctttagcttc caatttttct ttatcagaat agaacaagcc
    18841 ttcagcaccg tcaatttgtt caccaatcca aagagccatt ccacatccta ggaaagagat
    18901 gttagagttt tggtcaaata caacaatttc gttctcattt ccaaaattat ccaacatggt
    18961 attgatacat gctgtaccag cgtggttagc accgactaca acgattttac tcataaaaat
    19021 ttcctgcctt cattctaaat ttaccttact agtataccat ttaccgttag cgtttacaag
    19081 gggggtacta ttatttcagc attttttatc aaaaataatt ccccatttat cctgttttca
    19141 agcctgatga attttatgag catatttctt gactttttcc aaattttgtt tgtgaaaatt
    19201 ctaactttat ggtattataa taacatgaaa atgaaatgta agggcttcaa tttagatgat
    19261 tatttgatat tacaacttat tttctataag agaaaggagt tggtagcttg actcttcgtt
    19321 cacattctga acggctaatg gggactacta tcactatttc attagtggat gagcaagccg
    19381 atatctttct ccaaaaatcc tttgacttgc tcaaagaact tgaataccgc ttcaacgcca
    19441 atagtcaaga atctgagttg atggaaatca attatcaagc aggaatagcc cccgtcacgg
    19501 ttcatccaga cctgtttgag ctgatttcac ttgggttaga gcatagccta gcgctctcta
    19561 gccacctcaa tatcagcatt ggtcccttaa ttcaaacctg gcgtatcggt ttttcagatg
    19621 ccaaggtcgc gcagcctcaa gaaattgaat cggtgctgcc tctaatcaat cctcatggta
    19681 tcgagttaga ttcttctact tctactgtgt ttttaaaaca gaaaggaatg aagatcgatc
    19741 taggttgttt agccaaagga tacagtgcgg ataaggttgc ccaatttctt aggaaagagg
    19801 gggtgacttc tgccttgatc aatctgggag ggaatatcct gaccattgga aaaaatcagg
    19861 caagagggga taacccatgg caaatcggga ttcaagaccc agccaatcct aggggaaatc
    19921 atttaatgac catccctgtt gtcaataaat ctgtcgtgac ttcaggcatt tatgaacgtc
    19981 acctgaccgt cgatggacaa gattaccatc acatttttga cagtcaaaca ggatatcctg
    20041 ttgaaacgga actagcgagt ctaacaatca tctctgataa atcagtcgat ggcgaaatct
    20101 ggacgactcg actctttgga gaaagacctg cttctatcct ctggcaagtc gaaagtttgg
    20161 agggcatcga agtcatcctc atcgataaag aaggccacct aagctgttct tcaggaattc
    20221 ctactctata gagacaactg tttcaatgga attttaaaat tgtattatgt aaaaagagaa
    20281 aggaaatctc atgttaaaac ttattgctat tgttggaaca aattcaaaac gttctacaaa
    20341 ccgtcaattg cttcaataca tgcaaaaaca ctttgctgac aaagctgaaa ttgaacttgt
    20401 tgaaatcaag accattcctg tcttcaacaa accagctgac aagcaagtac ctgctgaaat
    20461 attggaaatt gctgctaaaa tcgaagaggc agatggcgtt attatcggta ctcctgagta
    20521 tgatcactct attccagctg ttttgatgag cgctcttgct tggttgtctt atggtattta
    20581 cccacttttg aacaaaccaa tcatgattac aggtgcttct tacggtacgc ttggttcatc
    20641 tcgtgcccaa ttgcaacttc gtcaaatctt gaatgctcct gaaatcaagg caaatgttct
    20701 tccagatgaa ttcttgctct cacactctct tcaagcattt aacccaagtg gcgacttggt
    20761 tgaccttgat gttatcaaga aattggatgc catctttgat gacttccgta tcttcgtgaa
    20821 gattactgag aaattgcgca atgcgcaaga attgcttcgc aaagatgctg aagactttga
    20881 ctgggaaaat ttgtaagata ggagaccgaa agaatgaaat ttgttggact tgttggatca
    20941 aactacgatc aatcatataa ccgcaaactc ttggaattta tccgtcgcaa tttcaaattc
    21001 aaatttgaat tagaagtact tgaaatcgac gaagttccaa tgtttaacca agatgaaaaa
    21061 tgggacgaaa gcttccaatt gcgtttcttg tataacaaga ttacacgtgc tgatggtgtc
    21121 attatcgcca ctcctgagca caaccacact atctcagctt cactcaaatc tgtacttgaa
    21181 tggctttcat acgaagttca tccatttgaa aacaagcctg ttatgattgt gggtgcatca
    21241 tactatgacc aaggaacatc acgtgctcaa gttcaccttc gtaaaatcct tgatgctcca
    21301 ggtgttaatg cctacacgct tccaggtaac gaattccttc ttggtaaagc taaggaagct
    21361 tttgataaca acggaaatat caccaacgaa ggcactgtta aattccttga aacttgctta
    21421 gataactttg ttaaatacgt aggagtcgtt tcgaaattga aaaaaccaaa accaatcgaa
    21481 tcagaagact tggattgtgg aaaaccaatc gctacaacca tcacagaagt tgaccctgac
    21541 gatccagaat gggtagaaaa agttgcagca atcactggtg ctgtttctgg tgatacctat
    21601 gtcaaattgg accacggtat cctaacagtt aaccaaattg atatgttctt gaaagctatg
    21661 ccatttgaat tgacatacgc tgacgacaac aaccaattcc tctactacaa caacgctcac
    21721 caagatccag acactatgtt cgctaaacgt gtaccacctc aatcaggtag ccgtatgtcg
    21781 actgttcatg gttctcttcc accagcacgt atgaagaacg tagagtgggt tatcggaaca
    21841 cttcgcaacg gaaaccaaga atacgtccgt acgatcgttc caggttctcc tgcaggtgtt
    21901 atcaacactc acaactacca agcaatgtac tatcctgatg gatcatacgc tggtatcaat
    21961 gaaatcgtct ttaacttcca accatggctt gactggtacc taaaagagac tggtcaacgt
    22021 ttggtgggtg gtagcggacc atttgctcct gctgccggag gtcatggaga cgccgatgct
    22081 acttctggcg cttctgattc aggggatgct ggaggccacg gtggtgacgc agacgctaca
    22141 gccggtgcaa gttactaatg atagttttta ggaaccatta tggttccttt tttagcgaaa
    22201 aaagactagc aaacacaaac tgctagtctc tttgttaaaa gaaagagtat atattatgaa
    22261 tttgggtcat caagactacg gccatgtaat cctttttcac gttgtacttg gcgtagtttt
    22321 tctggtgtaa catcgtttcc ttcttcgtcc acaattttga ttccttcaat gtggtgacga
    22381 acagcgcggc gataaccttc gatgtactcc tcacgtagtt tggcttgttc cactttttct
    22441 tctggtgtta agccttctgt ttttttcttt ttagcaagct cattgatacg agcaattttt
    22501 ttcggatcca tttcttctcc tttgtaataa gataaagtcc gtttatcaaa ttttatttag
    22561 tgttaatttg gttaaaacaa gcaaacttag ctgctttctt ggttagttgt gacaagattg
    22621 ccaaacgatt ttgacggaca gcctgatctt cagccattac catagtattt tcaaagaaag
    22681 catcaatgac tgggctaagc gcaaagagtt gtttcaattg ctgacttgca ggtcctgata
    22741 aaacgagtgt ttctactgct tctgccaaag ctttttcttg gtcattctca aatagttctg
    22801 aatcaactgt agcaacccct tctgccttct cagccaggtt aaaggcacga gaaagtgatt
    22861 caacagatgg tttaaaatct tcttccttgc ttacttctac gagagcactt gctgcttcca
    22921 acatatctgc cacaacaaag tttgaacctg caagaactgc ttccttgata tcttttggag
    22981 tagagcccat catcttatca acacgagcct tgataaagtc cataacctct gctttatttt
    23041 cataagtcaa actgtcaaat ttcaatgcat aaaggctatc aatcagctca tccatagcaa
    23101 tgtgccaacc aaaggcatcc aagatacgaa ccacaccttg agttgcacga cgaagggcat
    23161 aagggtcatt agaacctgat ggaatcaatc ctactgagaa gaaactcaaa atcgtatcca
    23221 atttgtctgc aatggctaga actgcgccga ccttgctctc tggaagttct ccttcagctg
    23281 atgtaggcat gtagtgttca cgaatagcag ctgccaccgc tggagtttca ccagcaagaa
    23341 gggtgtattt ttcacccata attccttgga gttcgtcaaa ttcaccaacc atacctgtca
    23401 acaagtcaaa cttgtaaatg gctgctgcac gagcaaggtc aactgtttca tccactgaca
    23461 aaccagcttt ttctgccaaa agtacagtga tttgacccgt acgaatcatg tgttcacgaa
    23521 gggaaccaat cttctcatgg aaggtgacat tgtttaattt ttcaacaaga tctgaaatca
    23581 ccaatttttg gtcttcacgc cagaagaatt ctccgtcttc caagcgggct accaagactt
    23641 tttcatttcc tttgatgaca tttttcaaac gctctgcgtt tccgttacga acagaaatga
    23701 agtttggcaa gagttttcca tcttgatcac gaacaacaaa gtaacgctgg tgttccttca
    23761 tagaagtcac caagacttct tctggaactt caaggtattt agcatcaaaa cttcccatga
    23821 aggcagttgg gtattcaacc aaattcaaga cttcattcag caaatccgca tcaatttcga
    23881 tacgtacacc atgttttgcc tcaatttcct tgatttggtc aacaatcatt tgctcacgtt
    23941 cacatggatc tgcgattaca aactgcttac gaaggtcttc ttcatagctc aatgctgact
    24001 gaattttggt ttctttcccc aagaaacgat ggccacggct cacacgactt cccttgatat
    24061 caaggaaatc caagtcaaac tcttgctcat ccaagagaac agttaaagtg tggacaggac
    24121 gaatgtattc aaagctattt ccagcccagt gcatgctgac agggaaagtc aatgacttca
    24181 agacatctac aacaccagga acaatggctt caactgattg gccaacttct tccttagtga
    24241 catagacata ttcttcaccc ttaatttcac ggaattcgat atcttcaaca gtcaaacctt
    24301 tcccacggac aaatccttga gctgctttgg tgaagtttcc atcactatcc aaggcaattt
    24361 tctttgctgg tcccttgaaa tcttctgtca aatcagactg tttgtctgat aaaccagtca
    24421 cacgaacagc caaacgacgt ggtgttgaga aggtttgaat ggcttcaaaa gacaggcggt
    24481 tttccttgag gaaggctgcc attttttcgc ctagttgttt ttcacttggt gtgacaacat
    24541 aggctggtaa ttcttcaaga ccgagttcta ctaataagtt ttttgtcatg ttttttctcc
    24601 gaaaagtatc tttttatttt ccagtttgcc ttatgtgatt ggcacgcaag caaccaactt
    24661 cgttgtttca ttgctaaaat tggagccaaa agtctccaat tttgcctagt atccttagtt
    24721 tcactaagga taccttcatc actgcggcaa ctggctcagg gctcactctg ttcgcccatt
    24781 ttcgtaattt gtcactctct ttattctgcg tcttctgcta ggagtttagc tcttgtttct
    24841 tcatccaaaa gtgggtagcc taggcgtttg cgttctgcga caaaggtttt ggctacgaca
    24901 cgggccaagt tacggatacg agcgatatag cctgcacgct ctgttacaga tacggcacca
    24961 cgcgcgtcaa gcagattaaa ggtatgtgaa catttgagaa catagtcata ggcagggtgt
    25021 accaagcctt cttctaatgc acgaccagct tctttttcaa acttatcaaa gttttcaagc
    25081 aacatttctt ggtccgaaat ttcaaatgaa tattttgagt gctcatactc aggctggata
    25141 aagatttctc cgtattttac accatcagcc cactcgatat catagacaga gtctacttct
    25201 tgaatgtaag aagccaagcg ctccaaacca taggtaactt ccgcagtcac agggccagtt
    25261 gccaatccac cgacttgttg gaaataagtg aactgagtga tttccattcc gtcaagccaa
    25321 acttcccaac caagaccagc tgaaccagtt gatgggtttt cccagttgtc ctcaacaaaa
    25381 cgaatatcgt gctccaaagg attgattccc aatttttcca aagactcaag gtaaagttct
    25441 tggatatttg atggagaagg cttcatgacc acctggaatt ggtggtgttg gtagagacgg
    25501 ttagggtttt ccccataacg accgtcagca ggacgacgtg atggctctac ataagctgca
    25561 ttccatggct caggtccgat agcacgaaga aaagtgtaag gactcattgt tcccgcacct
    25621 ttttcattat cataagcctg cataagcata caaccttggt cattccaaaa ttgttgcaaa
    25681 gtaaggatga tttcctggaa agtcaatttc ttagacattg tttactcctt tttatataaa
    25741 ttacttgcga catgaggctg cctcgtcgat catacgaggc aagacgagtt agtactgcgt
    25801 ctagctcagg cactctagtg ctgagcgtgg ggcagtccga ctgtaaggag gtttctgcca
    25861 ctgatgcagt gaaatgttaa tttctcagac attgaatact ccttaataaa aaataatttc
    25921 ttgcgacacg agtctgcctc gtcgattata cgaggcaaga cgagttagta ctgcgtctag
    25981 ctcagcaccc tagtgctgag cgtggagcag tccgactgta aggaggtttc tgccactgac
    26041 gcagtgaaat gtcaatttct tagacattgt ttactccttt agtttttata tttctttttc
    26101 aattaatttc tgctgaacaa accaatctaa caagggaaaa gttttttctg tatttgccca
    26161 taaatgataa gaatctaaga ccgcttgtac actacctaaa ttttctacca acttatctac
    26221 tgtcaaaaag ctgcgccagt attcataaaa aatacttgca tagttcttat cataagtcga
    26281 agaaccaaaa tcattcaatg aatgccaacc atacttcttc tgaaaaagtt ctacgagaga
    26341 ttgattacaa attttttccg cttgaaattc ctcttctgtc aagaaatact tgcgactaat
    26401 atattcaacc atcccctctt cgaaccagat ataagagtca taaccatcaa aatcatctaa
    26461 aaaatgctcc gaccaatgag ctaactcatg tcctacaatc tgtaagagga aattttcaga
    26521 taaagaatga tagtgacttt ctattgcttg agtttgctga gaacactcgt agtccatcaa
    26581 ttgatacaaa tacaactctt tccaaacagc taaatcaggc gccataacca ttcgtctatt
    26641 atttgtatag gctggaacag cgctttccct aataatctgt gtagcagcat taaaatctga
    26701 ccaaataacg gcttgcgata aatcacagac tgcaagttca ttctttaaaa aagattgata
    26761 atctttcaac ttttcagtat ttcttactac aaaatcacga aatgtagcta gttgactatc
    26821 gtcttttaca agataaaggt tgtccacggc tctcctttct ttcacacaat agactgaata
    26881 agcaaaagaa ccgcgtccga caatcctagg ttgatttaac ctaggggcgt cagaaacgcg
    26941 gttccaccct aatttattac ttcattgttt ttgaaaatac tacagaaagc gccagctcat
    27001 tattttgccc tacttggctc ccactatccc aagctcgctt gaagaacgcc ataagacttt
    27061 ctttcctgct gactattata tcaaaaatta gaataatgta caattctttt tatgattttc
    27121 tagaaatcca catcatcaac tcgtggagca cccgattgaa cagcaatcgt ttttaaggtt
    27181 tctctctcct catgactcag ttcaattcca aagcaatcaa gattagcttg aatacgagag
    27241 gttgtgacag attttggaag tggtaaaaat ccttctgcca agctccaggc caaggctatc
    27301 tgagcaatcg attttccgtg atttgctgcg atttcttgca cttgcttgct atcaaatagt
    27361 tctccctgac caaaaggccc ccaagcttcc aataaaattc ccttttcacg acagtaagct
    27421 acgacttgat cttgatacac acctggcgcc aagcgaactt gattgaccgc aggaacgata
    27481 gttgcagttt caagcaaggc atccaaatga tggggaagaa aattgctaac gccgatagca
    27541 cggattttcc cttcttgata gaggtcttcc atcgctctcc aaacttccgc attgcgagtt
    27601 ttccatgcgt cattttctct gagcggtttt gggttcggcc aatgaatcaa atacaaatcc
    27661 aaataatcca agcccagttt ttctatagat ttttccaaag cttgacgagt ttgctcatag
    27721 gtttgctgac tattccaaag cttggtagtt acgaacattt cttcacgtgg aactccgcta
    27781 tctttgattg cttgaccaac actttcttca ttctgataaa tcgccgccgt atcaatatga
    27841 cgataaccag ccttcaaggc ttctaacact gcacgatagg cttcttctcc atccttagcc
    27901 ttaaaagttc caaatcccaa tactggaatt tctactccat tatttaattg ataggtattc
    27961 atatgcttct ccttctattt tattcatcaa ttatagcata aaacattttt taagtagtac
    28021 tatcttctgt aaaaaataag tctgtcaaat atctaacaga cctatttttt cttgcttatt
    28081 catcacgact atagtacagc tcatgagctt ttaggcgagt attgagcatc tctggtatgg
    28141 tcacaaaggt ataaccttga tttttcaaat actcaatgac ccttggcaag gcattgactg
    28201 tcggactgtg aatatcatgc atcaaaacga tagagccgtt agctacttga tgctgaattt
    28261 ctgtcaaaat agatgcttca tttttactct tccagtccag actatccaca tcccacatga
    28321 taaagctcaa atccaagcta ttgcgaatat catctgtaat agcaccataa ggtggacgca
    28381 tgagtttaga actagaaccc agcactttag ttagcacatc ctcagtatca gtaatctgct
    28441 ttttagcttc atcaagagag agttgcgaga gaatcggatg gctccaacta tggtttccaa
    28501 caacatgacc ttcagatttt atcctcttca ccaagtcctc attcccagaa acatttttcc
    28561 caagcacaaa gaaagtcgct ttaatatcat atttagctag ggtctctaat acctgcgggg
    28621 tcgttgctgg atttggacca tcatcaaagg ttagagcgac aactttttga tatttcttat
    28681 caaagtaaga ttggtacaag gccgcatctt tttcgagtaa gtacgaagat tggataacat
    28741 caaagaaagc agatactggc aaggctatct cttctaaatt ttcaaccaca ggacttggat
    28801 aaaggataat ctgactatcc ttgtaatcaa aattccatgc agacaagtct tggtcagaga
    28861 agttttttac aatctgctca ctctggtctt gctctatttt tttatcctct atgaaggagg
    28921 tcaactcttt tatcagctgt tccttagcct tactaacatc tgaaaacagt tggtcaagtg
    28981 taaaaggttg cccatcttct gttaagtgaa cctttcctag actggtcttt tcagtctctt
    29041 caaccttaaa agcaactaaa tcatagattt gtttggtcac attacgatta acgactccct
    29101 ttaaacctga ctcttcttgc tctgtatagt agaaaacaag attgtcctta ctttctagct
    29161 tgtccttaac atcttgattt atcaactccc taacagagga aatcactttc tccccttgga
    29221 gaggataata ggcaatcact tcggcttgcc cctgacgaaa atgctccttc tgatttccct
    29281 cactcaattg atcatctttc tcttttttga gcgattcaat cttttgctca aaactttttt
    29341 gctggtagat cttaaaagca ataaatccgc ctaataggca aatagaaatt gctaaaatac
    29401 caatcaaagc caataataca tgtctcgttt tcccgtgtct gccacgtcct agtctacttt
    29461 tattcatatt tatatcataa caaatttgag caataatttc aatgatacaa tttggcaatc
    29521 cacaattcct ctagcaagcc aaagcatctt acatcaactc caacatccgt atctgtagag
    29581 attatgtagt tttctatcta tggaatttct agtagattga agctagaata gtagacctat
    29641 acttctaaaa cattgttaga aatcgatttg attgtcctga tcgatttgtc ctgttcttat
    29701 ttcattttac tataaaacta tgagaagcta ggtcatctga gaagtaatta ctatcgacaa
    29761 ttgcgatagc gtatactggt gcaatttgtt tgtagctctg gtgggtatca ccttcacgtt
    29821 ggcgaatttt ttctaggttt tgattaacct gactgcacag ataagcccat aggcgattga
    29881 tgaaaaaatt ctgatgatga acctgaattt cgatgataac ttgggttcca ttatctaact
    29941 ccgccaagac atctatacta gtatagaaat cctgcgctga gtagggcatg gaaggcaaga
    30001 cgtgaatgtt acttccctcc aaaatcgtca cattttttgc tggcaagtcc agcatatcgc
    30061 ggataaattg acaaagcatt agttgggctg atacccggat gtctgagaat cctccttttc
    30121 ctcctttttc tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga
    30181 ttctatgctt ctatctattt attcggaaaa gaaagctttt cttcagaaga aagctaatag
    30241 cttatttgaa gttttctcct ctctgttgga tagtcccgtc tatctatgtt ataatgaaag
    30301 aaggatttaa aatcggaaaa ggagtattta tgctaaaatt aggtgtcatc ggaactggcg
    30361 ctatcagcca tcatttcata gaagcagccc ataccagtgg agaataccaa ctggtcgcaa
    30421 tctattctag aaaactagaa actgcagcaa cctttgcttc tcgctatcag aatatccaac
    30481 tattcgatca attagaagtc ttcttcaaat cttcttttga tttagtctat atcgccagtc
    30541 caaactcctt acattttgct caggcaaaag ctgccttgtc tgctggtaaa catgttattc
    30601 ttgaaaagcc agctgtcact caaccacaag aatggtttga tttgattcaa acagctgaaa
    30661 aaaataactg ttttatcttt gaagcagctc gtaattacca cgagaaagcc tttactacta
    30721 tcaaaaactt tttagcagat aagcaagtgt taggagcaga tttcaactat gccaaatact
    30781 cttccaagat gcctgacttg ttgactggac aaacaccaaa tgtcttttca gaccgttttg
    30841 ctggtggagc cctcatggat ttggggattt atcccctcta tgctgctgtt cgtctttttg
    30901 aaaaagctaa tgacgctact taccatgctc aacagcttga caatagcatt gacctaaatg
    30961 gagatggtat cctcttctac ccagactatc aagttcacat caaggctgga aaaaacatca
    31021 cttccaatct tccttgcgag atttatacaa cagatggaac cttgactctc aacacgattg
    31081 agcatattcg ctcagctatt tttgccgacc accaaggaaa tcaagtccag cttcctatcc
    31141 aacaggctcc tcatacgatg actgaggaag tcgctgcatt tgcacacatg atccagcaac
    31201 cagatctgaa tctctaccaa acttggctgt atgatgcagg ctctgttcat gagctactat
    31261 ataccatgcg ccagactgct ggcattagat ttgaggcaga aaaatgaaaa ccaaactacc
    31321 gactgaatgg caagaactga gtgaccaact cggtttccaa gaattcaccc ccattcaaac
    31381 tcaactattt gagctccttc ttgctggaga aaacctccta ggagtgagcc aaaccggaac
    31441 tggtaagacc ctagcgtatc tcctaccaag tcttctcaga ctacaaaaga aaaaagccca
    31501 acaactcttg attctagcac caaacacgga acttgctgga cagatttttg atgtatgtaa
    31561 aacgtgggca gaagctatcg gattgactgc tcaactcttc ctttcaggtt caagtcagaa
    31621 acgacaaatt gaacgtctta aaaaggggcc agaaattctg attggaactc ctggccgtat
    31681 ctttgaactc attaaactta aaaaaatcaa gatgatgaat gtggaaacca tcatcctgga
    31741 tgaatttgac caattactag atgattctca gattcacttt gtagagaaaa tcactcacta
    31801 cgcacctcgt gaccaccaac tggtctacat gagtgccacg accaagtttg accaagaaaa
    31861 gattgtgccg aatacacgca ctattgatct ctctgatcaa aaattggaca atatccagca
    31921 tttctacatg caggtagacc aacgtcatcg agtggatatg ctacgaaaac tggctcatgt
    31981 agaggatttc cgtggtctag tcttcttcaa tagcctgtca gaccttggga atgccgagga
    32041 aaaactacag tatcgtgata tattggctgt ttccctcgct agtgatgtta atgttaaatt
    32101 tagaaaaatc atcttagaaa agtttaaaga taaccaacta accctgcttc ttgcaactga
    32161 ccttttggct cgtgggattg atatcgatag cctagaatgt gtcgtaaact ttgatattcc
    32221 tagagatagc gaaacctaca cacaccgtgc tggccgtact ggtcgtatgg gcaaggaagg
    32281 ttatgttatc actctcgtca ctcatccaga agaaatcaaa aaacttaaaa agtttgcaag
    32341 tatccgagaa attgtcctaa aaaaccaaga actctatatc aaataaagcc ccattgctct
    32401 atacacatcc agtgtatgga gcttttttac aagcaattca attttatact catctgtttt
    32461 caaaaagcat tctagtccat ctccgattaa cgatgggctt tatcacctcc ttctccagtc
    32521 cttgtatgat atcttgaagt tgattcatga catcttccaa agtttgaaag gctttattct
    32581 taaatccacg tttacgaatc tctttcaaca cttgttcaat ggggttcatc tctggtgtgt
    32641 atggaggaat aaaggtaaaa ccaatattag tcggaatctt taaggtactt gatttatgcc
    32701 atatagcatt gtccataacg agtaaaagga taagcttgtg aaagctcttc taaaaaggcg
    32761 ttcatccact cagtattaca tctaccagct attaagaaaa atgattcgcc tgtatgggca
    32821 tcaacagctc cataacaata gcgaaattct cgtatatagt gactatggac atgtggacct
    32881 actcctattg gagaccaaca agatcccagt ttactgattc taccgaaacc agcctcatct
    32941 tggtacatca agcgaacctt acgaaaacgt ctactatatt taaatcgctt tcttgccttc
    33001 ttgaattgag attttatttt tagacgcgac aatggtttga gcgtctgttt tcctaggatg
    33061 ttctggacgt ggcataatat ttcgccagcc atggcgcttc aacagttgat agaaggcatc
    33121 acgtgtgtag gaacgaccta actccttttt ataagcctga aataaggcat caattgtaac
    33181 aaattctcct gcctctgtag ccttcaaatg acgggcaaga aaggctttct cttcctcaac
    33241 tgtcatatat gcatggttac gaccaccacg tgtttcttga aggagagagt cgagtccgaa
    33301 ctcctcatat tttttacatt ttgctaaatc gttgtttgat tacagtctaa aagctctata
    33361 atctctttat aagatttgcc catcagacga aatagaacga tttgaaggcg tttatgatat
    33421 ttagctgtac gagagtcttt taaaagtgtt ttgatggttt ggatttcttc tttagttgat
    33481 ttcatattac tattgtataa tgctttttga tttgagtcta gtattatact cttcgaaaat
    33541 ctcttcaaac cgcgtcagct tcgccttgtc gtatagatgt tactgacttc gtcagttcta
    33601 tctacaacct aaaaacagtg ttttgagcag tctgcagcta actttctata acaaaatgaa
    33661 ataagaacaa gacaaatcaa tcaagacaat caaatcgatt tctaacaatg ttttagaagt
    33721 agatgtgtac tattctagtt tcaatatatt atagtttgct ctttgatttt cattgagtat
    33781 tagttcaata tctaaaaaaa gaaccttgcc aagcaagatt cttttagtgt ctgacttaaa
    33841 taattgttct tctgggaact aaatcgaatt aagcttcgat ttctgtaacc atacctgaac
    33901 caacagtacg tccaccctca cggatagaga atgtagtacc ttgttctacg gcgattgggt
    33961 gaatcaactc aacgtcgatt gtcacgttat caccaggcat taccatttca gtacctgctg
    34021 gaagttcgat tgaacctgta acgtcagtag tacggaagta gaattgtgga cggtagttgt
    34081 tgaagaatgg agtgtgacgt ccaccttctt ctttagtaag gatgtagact tcacctttga
    34141 atttagtgtg tgggttgatt gaacctggtt tagcgataac ttgtccacgt tcgatttcat
    34201 cacgttgaac accacgaaga aggacaccta cgttatctcc agcaagacct tcgtcaagtt
    34261 gtttacggaa catttcaaca ccagtaacaa ctgctttttg agtttcttct ttgataccaa
    34321 cgatttcgat ttcgtcgttg actttaacga taccacggtc gatacgtcct gaagcaactg
    34381 taccacgtcc agtgattgag aatacgtcct cgactggaag aagcaatggt ttgtcagtgt
    34441 cacgttctgg ttctggaata tactcatcaa ctgtgttcat caattccata acgatgtctt
    34501 cgtatttaga gtcaccttca agagctttaa gtgctgaacc ttggataact ggaagatcgt
    34561 cacctgggaa gtcgtattct gacaataggt cacggatttc catttcaacc aattcaagca
    34621 attcttcgtc gtcaaccaag tcaactttgt tcatgaagac gataaggtgt ttaacaccaa
    34681 cctgacgtga aagaaggatg tgctcacgag tttgtggcat tggtccgtca gttgaagcta
    34741 ctacaaggat agctccgtcc atttgagcag caccagtgat catgttttta acgtagtccg
    34801 cgtgtcctgg agcgtcgatg tgagcgtagt gacgtttttc agtttcgtac tcaacgtgcg
    34861 cagtgttgat agtgataccg cgttcgcgtt cttctggagc agcatcgata gacgcatagt
    34921 ctttaggttg gttaactgat gaaggcaagc gacgtgccaa aacagttgtg atagctgcag
    34981 ttagggtagt tttaccgtgg tcaacgtgtc cgatagtacc aatgttaacg tgtggtttac
    35041 tacgatcgta tttttctttt gccatttgag taaaagcctc caataaaata tattttatag
    35101 atagacagta ggcaatacag tctaactttc cttactattt tatcaaattt cagctaaatt
    35161 gcaagtgttt tacaacgttt ttgtgaatta ttcttggtaa aaatttaact aactaataga
    35221 aagtactaaa tagacttatc cttcaaggag ttttcagcat tatccatcca ctcacttgct
    35281 gaaaatgtaa acagtctctg gtttatatag taaaatgaaa caagaatagg gcaaatcgat
    35341 caggacagtc aaatcgattt ctaacaatgt tttagaagta gatgtgtact attctagttt
    35401 caatctacta tacaacctca aaactgtgtt ttgaacaacc tgcggctagc ttcttagttt
    35461 gccctttgat tttcattgag tataaaattg cagataaaac gataacaatc ataggactca
    35521 gcagagtcaa tgtaggtcga agaatagccc ccctaatcgc ttattttata gcaaaatgaa
    35581 atagaaactg aacattttgt tgaggaaggt aaatcaattc ctcacaatgt ttgagaaaga
    35641 agggaggact attccaactt caacccacta taaagcaaac ttacaagata gggaacccat
    35701 ctccgataat attccgataa tatatagtag aatgaaaact gcacaatttg attggagaat
    35761 tcaaaccaat ttctcacaat gttttagaaa caagggtcta ttatttcaac tgcaacctac
    35821 tatagcccat tgaagctgga atagcccact aagacttcta aaccactgct ggagaggagt
    35881 ttgtttagag tttctttcat ttccctaaaa aatcaaaaag agagaaccag tctgatcctc
    35941 tcttacttat agatggtgct cactcaaatg ttaaaggagc tatttcttag agataaagga
    36001 atttgaatac agctactgcc gcaattgctg ctgcgatagg tgctactact ggtacccaag
    36061 aataccacca ttttgaatcg cctttatgct caccaagaac tgattttgga aggaaagcat
    36121 gaaggagacg tggtcccaag tcacgggctg ggttcaaggc aggtcctgta ggtcctccaa
    36181 gtgatgttac caaagccata acgaggaatc caagtgccaa gtgagccaca gaaagtcctg
    36241 aagcagtgtg tggagccacc tgtgctttaa tagccaagtc agaaaaatca actgtttgtc
    36301 ctgcttctat tgccttttgt ttcatgaatt gaagcacttc agcaccaaag aagtttttag
    36361 tcaaaccaag agctgcaaag aacaaaacaa atgaaccaac aaactcatta atcaaaccat
    36421 tgacagttgc tgcatatcga ctttcttttg taccatggtc aatacttgaa atagttgaga
    36481 aagttcccaa gatgttattt ggtttttcag ttttcaagta gaatggacgg tatgttgcca
    36541 caactaaggc ttggccaaag atagccccca agacttgcgc gataatgtaa ggtaccactt
    36601 gtgcccaagg gaaaagaccg ctaactgcaa gccctagagt gaaagcaggg ttgatgtgat
    36661 tcccagatac gttaccaaac atcaaggctg ggatcataac ccccatacca taaccaacag
    36721 cgatgacgat ccagccactt tggtgacctt tcgtaccttt aagttcaacg ttggcaactg
    36781 caccattccc aagaatgatc aaaatggcag ttcccaaaaa ttcagtggca tacttcagtg
    36841 cccatgtgaa atccatttgc tagattctcc ttaaaatttt ttagatattc cttattttat
    36901 caatttttac cctatttagc aactgatttc tggaaatatt tttaaaaaaa taggattcat
    36961 agtttcccag ttcaacgtaa ttgtaagcgt ttttattctt cacgaaagac ctcattctca
    37021 aaaccaggaa aaagcccaca tctgtgatct tttccttgtt cctagattct aaaatctatt
    37081 atttttcatc ttcttttttc ttgaagaatc ctaatcctag accagctaac aaggtcatga
    37141 taccagcact agccaaggta gcattagctt ctgtacctgt gtttggcaat tcctctctct
    37201 tacctgtctc ataagtcgga acttctgggt ctggattcac tggagtttca gtttttggag
    37261 tacctggttc tggagttggt ttatctggtg ttgataaacg gtcatacctt accgttattt
    37321 ctttatcact agagtctgac gtaacttctt gtgattcaac tgttggaata tctggatctt
    37381 tgtacttgtc aatcttacca gatataacct cgtcccagtt tcctgttgtc cattcaccgt
    37441 aggttacaac tcccgtgacc ttgttctcag tttttgtacg gcttaaggtt acaggttgaa
    37501 caacatcttt ttttacattt tggttcgtaa ctttatcaac gtaatgaatg atacgcgtta
    37561 tagtcttcgt ctcagtagag gttgctgttt tgggaaccac ttttcctcaa cattctcacg
    37621 gtagtaatag tcaactgttg caccgtcttc tggtacgcat ttgcaggagt tgctaccaag
    37681 gtgtatgttg ttttccttgt gataactcgg tcttctttgt cctcagttgt tgttttccct
    37741 tcaatagttt ttgattctgt ggtatactca gaacctatcg ctaaatcagc ttttataaca
    37801 gactctgcca acttctcttg gctaccttct ttatagtaat tggctgttac tgtagcagtg
    37861 gttggcgctt cgctttctct ataaactaag gtcactgttc tacctttgct tacaatattc
    37921 ccagttaaac ttgcagaatt tgtatctact tctttaaaag tataatattt tccgtcagta
    37981 gtagtcatgc tactgagttt tttatctgtg acattatagc tggtaccaat cagttgtttt
    38041 ttattggtaa tgtaggttcc gtcactttct ttttctccaa ttccagtatc atttttcaat
    38101 gatagcaaac gcccttgttc atcaacatag cgaactttca cattttctga gattagttct
    38161 gccaattctg aggttttttt ctttttcttg atttcttcgg ttattttccc tttctcttct
    38221 tcgggaatat ttagttttgg aatgattttt tcaacaacgg ttcgtgatgg ttccacagta
    38281 tcttggatga ctgaaaagtc agctagaatt gggagattat actgaacacg gtgactttga
    38341 gtgtttactc ctactctttc attattctct gaaaatactt gtacggtata agaaacaaca
    38401 tcttttccta atagaacatc cccagtagag aaatagccgc cttttcctag tttgctatct
    38461 ccagagccca cttctttcct aatcttatca gatagttttt taccagtcag tacattcgtt
    38521 cgcacaatcc ctttgtctac ccctacaaag tgggagaatt ttttgaactc ttcagaacca
    38581 gatctagccc aaccattatt aagggcattt gcttttgtat ttgtattctc tctcaaaggt
    38641 ttggcgatta gaattatatt catcggcgct tagagttgct gctatatctg actcttgaat
    38701 accaacttcc ttactaccat ttctagcggc agtatatgtg tatttatctg tttctacttc
    38761 tagctgatta tccttaacat gataggtaat tttctcctgg tataagagtc ttcagtagtt
    38821 tatatgctct gtcatcatct ttagctttag aagcagctga gtttagccaa gttggggtat
    38881 taggagtatc tttatcagcc tgtttcaaga cattattcaa gtcatttgct agcctattgg
    38941 ttatcctcac tgtgaaagtt ttcttccagt ctgaaccact tttattagac ttagatatgc
    39001 tcatgaaatc ctggtcaaca ttcaacacaa tatcgccttg ttttttagca tcttccgttg
    39061 cttctgcttc aaattgatca tggagttttt gttgctctgg tgtatagttt ttttatttac
    39121 acgatttaat gtactatttt ttattttagt attaagaact ccattaatac gatttttaaa
    39181 ttctgcttca aaaaatccct taatttgttg gtgcgcaagt tcaacattca aacctttctt
    39241 atacaagtct tcattctgat acaagtcttc attctgaacg atttcggcta cacggtgaat
    39301 ggtttgattg tataccgtct tctcttaacc agcagtatcc ttagttttaa tgactactcg
    39361 ataggttcct ttagaaccgt tatagtcatc tagttttaaa aaagcattcc aaacattcaa
    39421 aaatagttgg aacttccctt aataaatccg tcactttctt tttcaagata gcccaagctt
    39481 gctcaatagg attcaaatcc ggtgaataag gtggtagagg taagaaaaag tgtttatctt
    39541 ggatgcagag ttcatccaaa atgttcttgg gatgaaaact agcattgccc atgacaataa
    39601 catgaggtgt cttcaaagca ggtaggagtt gcgttttgaa ccactccaca aagaaatcgc
    39661 ttgtcatgct tttcttgtaa atcatgggag ctataaactc tccgtctact tgtcctgcaa
    39721 caattgaagt tcgctcaaaa cgacgtccgc taatcttttc atagactttc tcccctctag
    39781 gagcccctgc ataaggacga tagaggtagc ggtcgattcc tgtttcgtca atatatacga
    39841 ttggtaaatc ttttaggtta tccaaaatat caagaaactc agcgactttc tctggctctt
    39901 gttccttaaa gctcgtcatc tttttttaaa gtgaccttaa tctgctttaa agctgcccat
    39961 actgaaggaa cagcacaatc aaaatgtgcc gcaatttccc gtaaaaaagc atctggatga
    40021 gcctctacaa aggttttcaa ttcctctaaa ggaatctttc ggtttttgac gactcgcttt
    40081 ttcctctcta tgtgttcttg ttcacatctt tcttttccca cgtgaagaga gttctgacgc
    40141 caacaccaaa aaacttggct gcctcgacat ggctgtgccc ctctttgatg taatctaatg
    40201 ctcgctgttt aaaatcagta ctatatgcca tagctttatt ataatatgct tgtttaaaac
    40261 taagcaacta tatcaatgtt ttgttatgag aagacttact ttttttactg aaattgaatt
    40321 tttcctagcc tcaacatcat ataaccccaa aattcaatct gacctggttt gaagagatgt
    40381 tcgaagcaga taaggtttta ctaaaactta aaaaaatgat ataatcaaac tgattaaatg
    40441 ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa atgggttgat
    40501 tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa atatggacga aaaaactaag
    40561 gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg cttggttggt
    40621 gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg attggctcgt
    40681 ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc ctacgatagc
    40741 cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa acacggcatc
    40801 aaatcttacg tatttgaaag ccttcgtccg actccagaac tatcatttgc agttcgtcat
    40861 ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc atttaacggt
    40921 tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga cgctttgact
    40981 acttatatcc gtgcaatcga aaacccattt gcagttgaag ttgctgatgt ggaaactgaa
    41041 aaagcttctg gcttgattga agttatcggc gaagctgttg acatagaata ccttaaagag
    41101 gttaaggaca taaacatcaa cccagccttg attgaagaat ttggtaaaga catgaagatt
    41161 gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct tgcccaagca
    41221 ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga cttctcaact
    41281 gtaacatctc caaacccaga aagccaagca gcctttgccc ttgctgaaga acttggtcgt
    41341 caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt tggtgttgaa
    41401 gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg tgctatcatg
    41461 gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa tgccgctctc
    41521 tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta cggcgcaact
    41581 atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga attcgaagaa
    41641 aaacacaacc acacttacat gatgggattt gaagaaagct tcggttactt gattaaacca
    41701 tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact tgctgcctac
    41761 taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa agaatatggc
    41821 tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc tgaacaaatc
    41881 aaagcgatta tggctaaatt ccgcaacaat gctccaacag aatggaacgc aacagctatc
    41941 actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac tgttacaaac
    42001 ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc atggattgcc
    42061 gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt aggggaaacc
    42121 aacgaagaat cacaagctaa gattactaac atcgaagcag aaatcaatgc atttgtaaaa
    42181 taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca aatctaagca
    42241 attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat ctcatggaac
    42301 aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg caagaagctc
    42361 ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct tactgccgta
    42421 aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa agctcacatt tacttcatca
    42481 atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc tatggaatcc
    42541 caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt tgcgactctt
    42601 caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc taacaagtct
    42661 taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc gttttattgt
    42721 tcctaaaaca gttacatcag catttcatta cagaacattt taattttgga agtcaaatca
    42781 atttttaaca atgttttaga aatcacagtg ggctattcca tattcaatta tccagattca
    42841 atcgctatta tcgttttcct agattacaaa aaaactacgt tttgctaatc aaaacgcagt
    42901 ttcagccact attttatctt actgtccttc ttttacttct ttggttgcta catcttctcc
    42961 aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag aaaaagcttc
    43021 atttatcttc ttaaccaagt ttgtatcttc cttacgggct ccaaccgcaa aagcttctgt
    43081 ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt ctaaataata
    43141 gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca aatcaatcaa
    43201 ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat tcttcaaaat
    43261 ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc ctaatgtctt
    43321 tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca atacctgctc
    43381 attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg tagcggaata
    43441 gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca aatcccaatc
    43501 aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag ctaaatcaat
    43561 atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa aagtactatc
    43621 aaatccaata gtaatagact tgttagactg gtactttgac caattatctc cactagtttc
    43681 gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga ctaatacaag
    43741 catccatttt ttcatccatt tttcctccta tttaggttct actttcaata atacatctgc
    43801 gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc caagttccct
    43861 attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg cagaagttgg
    43921 ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag ccacccgctg
    43981 cttttgccca ccagatagtg agaaaggata ggcctctgcg tgtcctccta gtcctaactg
    44041 ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca tggtcttcac
    44101 aggcgataaa gtcaaatttt ccagaactga taaatgaggg aacagttgaa aatcttggaa
    44161 tacaaatccc agtagattgc gcttctgcaa ttcatccagc tctaaaggtt gtccattata
    44221 aaagatttgc cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa gagttgtctt
    44281 acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac ttagactgaa
    44341 attagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt ctaacatggc
    44401 agcctcctat ctataataac tatacttctt ctcaactttt ttggaaataa ttgtcacaat
    44461 cccaatcaaa atcaaataaa tggctcctgc caagaacata ggaactagac tagcatcgcg
    44521 gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcat agaccaaaga
    44581 agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga tcttggtcac
    44641 ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga ccttggcggc
    44701 ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg caaagtaagc
    44761 tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac gaatcccaat
    44821 acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc ctcgcataac
    44881 ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca aggcaaaggc
    44941 aatcaaaacg cccaagggaa tcgaaaatag caagaccagt gcaaagacct gtacagtcgt
    45001 gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac tgcacctcct
    45061 aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt tttgtaaaaa
    45121 gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta cagttctata
    45181 tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca tctggaacca
    45241 gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat tcacgcaaga
    45301 gatagatata gtgttccaga aattctggat tgtccttcaa atctcctgtc aactcttgat
    45361 aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca atcatccact
    45421 tggtcaaaag attttctggc tcctcactct gcaagtctag aatatcctca taacgctcct
    45481 gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca gcgtcttctt
    45541 ttgcagcaag aagataattt tctgcaccac tagcatcatg caattcataa gaaaattgtg
    45601 aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc ttagcgatac
    45661 gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca tactcatagc
    45721 cttcaaagtc aggagaaatg gtatcaagct gcttaaagta gagggtggct ttttgatatt
    45781 cttcttgatc aaaataaaga tttgccaact caaaagctgt taagtcatcg tattctaact
    45841 ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga gcataggcaa
    45901 agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga ttatctaact
    45961 gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac tctgccaaac
    46021 ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc tcacgtgcca
    46081 catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac gagacatacc
    46141 agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt tgaccatcct
    46201 cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca attttcaggt
    46261 aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc aactcataca
    46321 gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc ttagttaaat
    46381 cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac ttcctcaccc
    46441 tctaattcat atagaccact gactacctta taccattcga aaatggctga aatgacaacc
    46501 ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa catagatcct
    46561 gaagttaaca aaacaaagag aacattaata ggatggatgt ttaattgact tcccaaaatc
    46621 aatggagaga caaaacggcc ttcaatagtt tgttctacga taaagacaat cactactttc
    46681 aaaagcatga ctggaccagc aatcaaaccc aatactagag caggaagcat ggctagaaag
    46741 ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt aaccgcatag
    46801 cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat agccactgtc
    46861 acttgccctc gaacatagtt ggacaactgt tgattcacat ctgatagaac ttgtccaaca
    46921 ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc tttcccatca
    46981 cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac ttgagaagct
    47041 ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact tgccaaaact
    47101 gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa atcatctggc
    47161 aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta aacaggaacg
    47221 tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc caagccccaa
    47281 atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg attaacctta
    47341 tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc agacaaaatg
    47401 actggcaaca tcacaactgc caaaaagtct aaaacaggtg aaaatagaaa actaatctta
    47461 cttaaaataa aaagattcag tcccaataat aaggttacta aaaataccgt aattgccttg
    47521 ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt ttgctccata
    47581 aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata actctttttt
    47641 aaagtgctta catctaattg gatatcttta atttacttgt ttttgtgata taatagtctt
    47701 atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt atacacgtcg
    47761 tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc tttcaaatct
    47821 agaacttttt gcagctgagc cgagtccaac ctaccttgcc tttgaccagc accaacattt
    47881 atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa ctgacgggac
    47941 tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg tcgatgaaaa
    48001 gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt ataaacgcca
    48061 ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag gtccacatga
    48121 aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact atctagtgac
    48181 ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag gaaaattatc
    48241 taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca ttttccataa
    48301 ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag ttttaatcta
    48361 cgatggcgtt ggcgaatttg aacgtatgca ggttatttca actttaccag aagcttacga
    48421 aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc tctacgcttc
    48481 taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta gcttagagtt
    48541 attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga cacccgacca
    48601 aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta aacgtaattg
    48661 tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag cagtctgcat
    48721 ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt tcattttttc
    48781 ttatagtcta tttccgacat taatacggtt aatggcacgt tgcaaagcaa tcttagcacg
    48841 acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt ctgcacgaag
    48901 tttggcacgt tctgcacggc taatatcgat atcacgagca cgttctgcag agtcagcgac
    48961 gattgtgatc atatcattgg caatttcaat aacgccaccg tttactgcaa tccagttcac
    49021 gtgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa ccgcaatcat
    49081 attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg atacatagct
    49141 ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta actgagccat
    49201 aggtcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg atagaaccta
    49261 caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt tccttaaagc
    49321 cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat tgttccgcaa
    49381 cgttgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc aaggtctttt
    49441 cttcatcaga aagctcatcc ataccaagga tagcaatgat atcttgcaat tcatggtaac
    49501 gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca acgatttcag
    49561 gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata cccaattgta
    49621 ccaatttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt gctggcgctg
    49681 ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca gaacccttct
    49741 tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt ggttggtaac
    49801 caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc tgagtgaaac
    49861 ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg aagtattcag
    49921 cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca ttcatctgac
    49981 caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag taaaggtcat
    50041 tcccctcacg agtacgttcc ccaacaccag taaatactga aataccaccg tgctcttggg
    50101 caatgttgtg aatcaattct tggattaaga cggttttacc aactccggca ccaccgaaaa
    50161 gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg atccctgttt
    50221 caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta tgaattggct
    50281 gacgctctgc gtcttctgta aaaggagctt ccaaatcaat ggtatctccc aaaacgttga
    50341 agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct gtgtccaata
    50401 cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga accataccat
    50461 ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca tttttgtaga
    50521 cgacaagtgc attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa acgtctacaa
    50581 cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat tctatataag
    50641 atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag ctggactaga
    50701 gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt aatcgccgcc
    50761 tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc attatctgtc
    50821 gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc gataatggca
    50881 ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc ttctcggctg
    50941 gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc caagtcaaca
    51001 atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg gtggttgtag
    51061 caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt tgaaataatc
    51121 ttacgaactt gatcaaagct aggttggtct gccaagccac gtaattcata aagtggttga
    51181 ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat ttcaaaacct
    51241 ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat agaggaatta
    51301 taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt cttcacagaa
    51361 cgactaatca acatcggatt agttgaagca ccagctccat taccatgaag gatatctgtc
    51421 aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc ttcagagcga
    51481 cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt attttttgtt
    51541 gaggcgattt ttgttttaat atcatttaga gacactgcca tctgacacct ctattcttat
    51601 tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc ttcttctggc
    51661 aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc aaagaaggca
    51721 tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa gaaaccatgt
    51781 gtcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg aacaggttgt
    51841 ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc tgcgtccaag
    51901 tcagaaccaa acttagtaaa ggcttctaac tcacggtatg aagcaaggtc gatacgaagt
    51961 gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg agatacagat
    52021 gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc aaggaagatt
    52081 tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc tcctgcttgt
    52141 gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga aactttagct
    52201 gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc ttcacgacct
    52261 ggaggacgac gaagcaagag cgatagttca cgataagcta ccgcttgttt tgatagatca
    52321 tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat agcaacccca
    52381 gtataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt cacaacgatt
    52441 gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac tgttgattct
    52501 ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt caagattgta
    52561 tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc acgttgacca
    52621 cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg ttctgaaaca
    52681 gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt atcagtgtgg
    52741 atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc aatcagactt
    52801 tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc ttcacggata
    52861 tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt ttgagccata
    52921 ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc aaggccatga
    52981 gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac atcaaaattg
    53041 ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc gttaattgcc
    53101 aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt tgtttaatac
    53161 tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga ctttcatcga
    53221 tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa gggagcaaac
    53281 gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca aatcgatttg
    53341 tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga tttgctctgt
    53401 gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa tcttggaaaa
    53461 aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa aaagaaggca
    53521 gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata cggtcttctt
    53581 ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt acctttactg
    53641 ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga gtgctttatg
    53701 ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg tcaaatctgc
    53761 gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt cttgattggc
    53821 tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag ccttactttg
    53881 ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc taccagccaa
    53941 ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt cagctctgtc
    54001 aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat tagaccatgc
    54061 aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa taaaattacc
    54121 aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct tcaatattaa
    54181 tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg atgcaggaaa
    54241 taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga taccaataaa
    54301 tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca aagatattcc
    54361 caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata ttcatcggta
    54421 tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga cgacgaacgc
    54481 tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac tgtaaattag
    54541 cggttggcga actccaccag ttagtcccat cgatcgtttg aatctttgtc attaagccaa
    54601 ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgag taatctttca
    54661 tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag acatactcaa
    54721 gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa taaataaaga
    54781 caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg aagataacag
    54841 gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc ttttcttctc
    54901 gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa agttccttca
    54961 ataaaggcaa cacctaaaaa catcaaacta cgaaactcag aaagcatatc tggttggcgt
    55021 gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac gcccatacag
    55081 gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa ataaaattta
    55141 cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat tggaagcgtt
    55201 taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc cagaagtctt
    55261 ctctgggtga cttgtagtcc aagcattttt taggatagtt gttaatccac ttttcgatga
    55321 atgcgacttc tttgggagtc attttcttgg ttcccttagg taaccatcta cgaatgagcc
    55381 tgttgtgatt ctcattagtt cccctttccc aagaggcata ggggtgcgca taatagatgt
    55441 gctcctcaga aaatacatta gacaagcgat tgaattccgt tccattatct gccgtgatgg
    55501 aaagaatctt gtgttgtttt aagatgagtt ttagagcctg attgaccacc tcagcacttt
    55561 tatttggaat caatcggatg atctgatgtc tactctttcg atccgtcaag acaagcaagc
    55621 agtagttttt cgctctcgta agtagaaccg tatcaatctc ataatgccca ttctccaaac
    55681 gaagattgat agcttcaggc cgctgttcga tggattgacc agcaggttta aagttggtgc
    55741 tggcctgttt cttaagcgct tttccttttc tagggtaaag cagatcctgc ttgctttacc
    55801 ccaattttcc atgatgaatc caatagtaaa tggttgaaat tcccacgtta acccctttag
    55861 ccataaccat catttcaggc aaaaattttt ggttatgata gtggagaatc ttttccttta
    55921 gttccttggt cacgcttgat ctcttgaccg agtgcttgcg attattttca taagactgtt
    55981 gagcatagtc ggcagaataa acctctttga agcgcccttt tccaagacat tttcggactg
    56041 tcctacgctt gattttagtg tggatagttt gaggagcttt tccaagcaga gaggcaattt
    56101 ctctatttga tttccctttg ttcgcctttt gtagtataat ggttttgcat ctctgtgcct
    56161 ttcttgtgtt tgtggttgaa caacaagtat aacacagagg tgttttctta tgcctacaag
    56221 agctttcatt atttccattt tctttcggat ttcactctat tctgaaaaac ttgtgtatat
    56281 ttactgaagc tagcaagtct tacctgtaaa tttaatgaaa gcaacacaaa atccgagagg
    56341 ggaatctcgg attaatgtca atttaaaaag atagagagtt tttagtttaa ataaattgtt
    56401 ttaaaatatc aacaacatca cttcttttct taacctgata agccttgatt cctaattttg
    56461 gagctacgat tatattgtcc tcaatatcgt ctagaaagac acaatttcta ggttataact
    56521 ggtatttatc gatagttact catatacatc agtccacctc catacttatg tgcgagcctc
    56581 tctttgtatt atacctccat actcacctta cagattcttt tggtaataat atctttgcct
    56641 aatgtagaga tagtcttgca aagaaaaaac ttccttgtag ccatgtttct gataaaagtc
    56701 cggtgcctgg aactgataag tattgacaaa ggcaaaacaa caatttcgat tcttagcttc
    56761 actttctgcc tgttgcaata gttttgaacc gattccttgc cctcgcagtt cctcttttac
    56821 aaacaaatac tcgatttcta gccaatttcc aaaagtctct gctatcaaac ccgcaaggag
    56881 attgcccttt tcatcttcga cataaagatt aagtggctca ctttcagcct cttccctttt
    56941 tgaacggtta taaacacgaa tcagattccc tatttcttgc gatttatgtg attccttatt
    57001 ttccaatcta aagtataatg aaatgaaata aaacatgcgc aaatcgatta aggaatttaa
    57061 tctaatttct aataatgtct tagaaatcaa agtttactat tttaacttca atgcactata
    57121 catctaatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa
    57181 acactgtttt gaggttgtag atagaactga cgaagtcagc tcaaaacatg gttttgaggt
    57241 tgtagataga actgacgaag tcagctcaaa acatggtttt gaggttgtag atgaaactga
    57301 cgaagtcagt aaccatatat acggcaaggc gacgctgacg tggtttgaag agattttcga
    57361 agagtagcaa aatggaaaaa ggagtgagtg aagcacatcg cctccccact cctttttctg
    57421 tttttaggct gttttttcaa ccttcaagat ttttacatca tagctaccaa caggcgtttc
    57481 aattgttgct gtgtcacctg ttttcttgcc aatcaaggcc tgcccaattg ggctttcatt
    57541 tgaaacctta cctgcaaagg catccgcacc agctgaacct acgataatat aaacttcttc
    57601 ttcgtcctcg ccaatttctt ggatggtgac tgttttacca atcgctactt cgtcctgggc
    57661 aactgcgtcg ctattgacga tttcagcata gcggattttt gtttctaagc tagagatttg
    57721 tccttcgaca aaggcttgtt catccttagc tgcttcgtac tcactgtttt ctgaaagatc
    57781 accgtatgaa cgggcaatct taatgcgttc taccacttct ggtcgacgaa ccaatttcaa
    57841 ttcttctaat tctttttcaa gtttctcctt ttcctcaagg gtcataggat atgttttttc
    57901 tgccattttt ctcaactttc ttctgataat attttctaaa gaaaattatg tgacgtatca
    57961 cataatttta gtttgtttag tttaatttgc tgttgacatg ttcagcgaca ttgcggtcgt
    58021 ggtcttcttg attgttagca tagtagacct tgccttctgt gacatctgct acaaagtaga
    58081 ggttatcgct cttagtttga ttgatgcttg actcaatcgc atccagactt ggactatcga
    58141 ctggaccagg catgagacct acatttttat aaacattata aggtgaatca atgttggtat
    58201 caatcgcaac atcctcagct agactgatat tttgccccag ttttccttgg gcatacaaga
    58261 ttgcaatatt actttgaagt ggcatatcac gatttaaacg attgtagaat acacctgcaa
    58321 tgagcttacg atcttctgtc ttggcacctt ctttttcgac caaggaagca atggtcaaca
    58381 actcattgac agtcaaattt ttagatttga tagtactata gtaaggagat aggttcttat
    58441 ccatagcagc taacatctca tcaatcaagc tctcaatagt tgtgctttcc ttgatagagt
    58501 atgtagctgg gaaaaggtat ccttccaaac gataacgcgc accgctgtct tttacaggca
    58561 aactttccag taaagtagga tatttcgcta ctgcttgact gataaacgtc tcatcttgaa
    58621 ctttagccaa gaaagcctcc gctgtcaaag actctttgaa gtcaccttgc aattgaccca
    58681 cagcttgagc aatctgatcc aaggtataac cttctggaat tgtcaaagtc gcaagtacag
    58741 gttcttgcgg ttcatctgtt ccaccttttt gcaactcttt gagtaagtct tctgtactca
    58801 tactcttttg caaattgtag taacctgctt tcaagtcggt ataattttta tacttggcat
    58861 aaaaactaaa aatcagacca tgctttacca aaccagcttt ttcaagcgtc gtaccgattt
    58921 cttgaacgtt tgaaccttct ggaattccaa ccgtcacata tttcttagaa ttagcatcga
    58981 taggtaacaa agaatctagc acgtactggt aaccaaagta accacctgct gagagcaagg
    59041 caaggaatac aaggaatgaa atcacaaaag ctttcacatg tgacttcttc tctttcttag
    59101 gattaacggg ttttgctcct tctctacggc tacgacgtga tgtatcgctg atgatatcca
    59161 ctgtttctgt agcaggcgta ggtgtttctg gacctgcttg ttctgctttt ttctctgccg
    59221 tcgtatagga aacagctacc cttgttgggg tttcattgta ttctctttca agtttcttag
    59281 gtctaacagg acctggacct ggtcttgatc cactttcttc cgctggagaa gaaggtacat
    59341 cttgacttgg atgacttgga acaccaggag tttctctttg aatctcatct gctggagaag
    59401 ctggtacacc ttgacttggg tgagtagaca cggtaggagc ttttctcata atctcctcta
    59461 ccgttgacaa ggaatcagcc atgagttctt cagctgaagg ttcatttgca ggagtgcgaa
    59521 ctactgcctc atcttctttc agaacttcat catagccttt tactttttct aaatctctca
    59581 gaatctgctc tttaaagctt aatttctctt cttctcttga cttttcactc aaaagttttt
    59641 cctccttgtt gataatccat aatattatat cttaaaagtc caaaaaaagc aatctatgat
    59701 acttttccta acttattttt tcatttccca gaccatatca taccatgttt cccctgcaaa
    59761 ggttgactgg gactggcctt cgttgacaaa tccatgtttt tcatagtagg cgatgagata
    59821 gtcatgacag gttagattaa tgccatctct ctcatcttca agagcaactt ctttcaaggc
    59881 tgtcagcaat ttctgaccca gtccgagtcc ctgtgcctcc ttggcaatag acagacaggt
    59941 cacagagata taaccaccag gctcatgact atagtctttt atttcttctg taaaagactg
    60001 gtcttgcaga tggcggtgca ggccaactgg tccttcgata taacccatga ttcttccttc
    60061 tttttcagca accagaaaag aggtctgaat ttctctcaaa tgtgcttcaa agacagaagg
    60121 aggaatggct tcttcgaccg aaaaattttc aaattcaagt tcaacaatcc gatccaaatc
    60181 ttctaatctt gcttgtctga ttttcattgt tcctccagat aaaagggatt aaaccaaatc
    60241 atactatagc cctggctagt tgcatagagc aaagttgctt cttcatcaac aaaaccgttc
    60301 atttcaaaat aggaaagcag ctcatcagga ctctccaaac gaatcccttt gtaatccagc
    60361 tcaactgcca cctctttcaa ggctgcaaga agaagtgttc ccaagccctg tctctgatgg
    60421 tcagactcga tgactaaaga atgtactttt agatattgcg gattgtctga ctggggactt
    60481 gataaaatat agcctaaaag ttgattttca tccctagcta gaagaaaggt atccgcacac
    60541 ttacggatac tttcttctaa aatatgggaa agttgctgct tttcagctgg aaaagacgag
    60601 gtctgaagtg cccctatctc aggcaaatca gacttgcttg cctgaatgat cttaattgga
    60661 atttccatgg gaacatccta ttgaacattg cttgtcaagt tagacaagag acgctcaaat
    60721 gagtattcat aggtttggat gtctcctgct cccataaaga cgtaaacagc attgtcatgg
    60781 tctaggagcg gagaaacatt ttcaacagta atcacttggt gttttttgtt gattttgttg
    60841 gctaggtctt ctaccttaac gtcaccatga tctacttcac gagccgagcc ataaatttgc
    60901 gctagataaa cagcatctgc ttggtttaaa gcatgggcaa agtcgtccaa caaggcaatg
    60961 gttcttgtaa aggtatgcgg ttgaaagact gctacaattt ccttgcttgg gtatttctga
    61021 cgagccgcat ccaaggtcgc aataatttct gttggatggt gggcaaagtc atcgataatc
    61081 actgtatcat tgacaatttt ctcagtgaaa cgacgtttaa caccggcaaa tgttttcaag
    61141 tgctcacgca ccaagttcaa atcaaatcct gctgtgtaaa gaagaccaat aacggctgtc
    61201 gcattcatga tattgtgacg accaaaggtt ggaatgtgga attgccccaa gttttgtcca
    61261 cggaaatgaa cggtgaaggt tgaaccagtt attgaacgaa gaagatcact agctacaaag
    61321 tcattgcctt caacttcaaa accataataa taaattggtg catcagacgt aatcttacgc
    61381 aattcagcat cttcaccata gacaaaaaga cccttggtga tttgtttggc atagtcgtta
    61441 aaggcattaa aaacatcctc gagacttgtg aaataatctg gatggtcaaa gtcaatgttg
    61501 gtgataatag agtattctgg gtggtaaggc atgaagtgac gctcatattc gtcagattca
    61561 aagacaaaat atttggcatt ggccgaacca cgacctgtcc catctccaat caagaagctg
    61621 gtatctgtaa tgtgagacaa gacatgagac aacatacctg tcgttgaagt ttttccatgt
    61681 gctcctgcta ctcccatgct aacaaagtca cgcataaagc tacctagaaa ctcatggtaa
    61741 cgtttgtagc tgataccatt ttggtccgca taggcaattt cgacgttgtt atctggacga
    61801 aaggcatttc cagcgataat ttccatatca ccgtctagat tcttttcatc aaaaggaaga
    61861 atggtaattc ctgcctgctc aagaccgcgt tgggtaaagt agtacttttc aacatctgat
    61921 ccctgaacct tgtgccccat ctggtgcaac atcaaggcca aggcactcat ccctgatccc
    61981 ttaattccga taaaatgata tgtctttgac atgttttctc ccctattctg tcattctggt
    62041 cagattcaac tcttgggcaa cccgacgttc ttgttctgtt tgtttacttt ttttattgta
    62101 gatttggctc ttctttagaa aatcataatt gtttttcttt ggagcaggtg ctgacacttc
    62161 ttcattcttg gtagggatag aatgaacttc ttccgccaag atataatgag actgggtcaa
    62221 tttttggcta tatttgacaa attcaccagg attttccttt tggaaaggag ttgtcggttg
    62281 attgccctgt ctaactagac tgggctgaga atgacgtctc gcaaggctga aatcctgagt
    62341 taggtagtta gcagagcgtt tctttttcaa gtccgcacgc gcttcttcac gcgccacctc
    62401 cgcatagctc tttccttctt ttttaacccc taaaggagcc tttttaggtt tttcgacttg
    62461 cttttcaatc ggttttactg gtttttcttc agcaatagga gcccattcta aataattttt
    62521 atctcgatac tcacccttga tattactgat cagatcagac tcatcataga gattcatgac
    62581 tggcatttca gtcaacatga cctcgtcatc tgacaccaat ggaaatcgtt cttgtttcat
    62641 tttctatttc ctttcaacac ttcattatag cgtattgtct tgatttttca agtgctggct
    62701 tcagaaattc ccaaaatttc tctaatttct gctagggtca gactaccacg tgactctgtg
    62761 ccgtccaata cttgtgacac cagatgtttc ttttgttctt ggagttcctg aattttttct
    62821 tcaatggttc ccttggtcac caagcgatag acctcaaccg tttcttcctg acccatccga
    62881 tgggcacggc caatggcttg cgcttccacc gcaggattcc accaaaggtc aaccaagatc
    62941 actgtatctg cacctgtcag gttcagaccg accccaccag ccttgaggga aatcagaaag
    63001 gcatctcttt ctccttggtt aaaggccttg gtcatgtctt gtctttcctt ggctggggtt
    63061 gaacccgtaa ttttaaagga agtcaggccc aagtctggca gttcttgttc aattttttcc
    63121 aacattccct tgaactgaga gaaaatcaag acacggtgtc cgccgtctgc cacctgtacc
    63181 agtaggtctc ggagactatc tagtttgccg ctggctccct gataatcttc cataaacagg
    63241 gcaggagtgt cacatatttg acgcaagcgc atcaaaccag ataaaatttc cacacgactt
    63301 cgctgaaatt cctgttctga cacttgagcc agatggtctc gcatctgttg taactgggca
    63361 aggtaaatag ccttttgctg gtcttccagt tcatttttat aaaccacctc aatcaagtct
    63421 ggcaattcag tcagaacttc ttctttcttg cgtcgcatca cgaaaggctt gataaactga
    63481 gccactcgct ctgctggcaa tttcataaat tctttcttgc ttggcaaaag tccgggcatg
    63541 acgatttgga aaatagacca caactcaccc agatggtttt caatcggagt tcctgacaag
    63601 gcaaagaccg acggcaccac aaattgtctc aaggtctggg caatcttggt ctgggcattt
    63661 ttcatgacct gagcttcatc taagaaaagg aagtcaaagg ccatcccctg ataaagctca
    63721 ctgtcctgac ggaaggtggc atagctagtc acatagattt gatggctatc ggcaagaatc
    63781 tcctcacgac ttgctttcaa accatgaaca acagccacat ccaactgtgg ggcaaatttc
    63841 tgaaactcat ccgcccagtt gtaaatcaaa cccgacggag cgagaatcaa gactcgactt
    63901 tcttttgtca cttgactagt caaaaaagca atggtctgaa gggttttccc aagtcccata
    63961 tcatcagcca aaatcccacc aaaaccataa tgatggagca tctgcaacca gccaattccc
    64021 ttttcctgat aatctcgcaa gtcagccttg acctgagttg cttgcaaagg aaagtcctct
    64081 ggatgcgtca aatcctgggc cagattctgg aattcttgtg aaaaagaaac acggtctcgc
    64141 ccttcaaaga gatgagctaa actgtaggcc aaggatttcc gagcctgcaa ggtcccatct
    64201 tttaattcaa attgccccag ttcctgtaga ttttggcgaa ttttcttggt ttcttcatcg
    64261 aaaaagtaaa cttgattaga cgaatcaata taaaaatcct gattggcaac caaggcctgc
    64321 atggcttggt cgatttcctc ctgggcaata ttttgaaaat caaactggat ttccaagaga
    64381 cctcccttgg aggcaatctg cacctgagga ctcgctaggc tataaagctc ttctagttta
    64441 tctgataggt caacatgccc gagtttttca aagactggaa tgatatcatg aaaaaaatga
    64501 tagacagact ccgcttttaa ggcctgacgc caagattgaa aatcggcttc aaagcccgca
    64561 gccaaacaga cttggaaaat tctttcttct aagtccgcgt cacttgaaaa tggtaattct
    64621 tctagctctt gtcggctaga tacctgtcta tttccataat caaactgaat ttctaaacga
    64681 atccgattat cttcttccct gtcaaagtaa aaagagggcg caaaagtttt gatttgtaga
    64741 cgttctggag ctgaaacggt gcccatctgg ataaaaagag tcagacagga ggccaatttg
    64801 tctcgatcac tgctatcaaa ttgcaggtat ttctttcctt gttgacccac aggtaacact
    64861 ttaatttcct tgagaagacg catctgctgg tctgttaaaa aataaacctg acctttatgg
    64921 aaaagtactg ctccctgata aaagacattg accctaggac tctcactgat ttccatttca
    64981 aaatagtccg agtattctgt tactgtaaag gcaaatagat tggtatcagc atgcatatcc
    65041 tgaaaaagca gggtttggta gctatccact tgatggtcaa attgaaaatg gggcaaggcc
    65101 atcagtaaat tcacaccctg ctcaaaaaag gtcagaggga aaaagaggtg ccgaccttgg
    65161 ttttggaaaa agaggtctgg aaccagccct tcctccgtta gtccgtgcaa gaaagtcaaa
    65221 agttcttggc tggcatcatc aaaggcttcc caagaaagag actcctcata aatcttgcca
    65281 atcatatacg actttctctg ctcgacaatc cttaaaaaaa gtggaatatc ccgaatgaca
    65341 tagtattttt gtctattgat ttggccgatt ctcagagtcc acaagatatg attggttcct
    65401 gcttccacct gacccacagc tgataactca taggcgcatt ctgatttcgg agataaaatt
    65461 cgattcaaaa acttgccacc caaggtcacc ttggtttcaa cggcctcttt ttcttcatga
    65521 ccttcttcca gactccacaa gatttcctga ccacgctcat catttttcag aaaatgctct
    65581 agcgctgcca aatgcacaca gtagcccctc ttttgaaaag aatcacaggc acaaaaaacc
    65641 aaatcatcct ctaaactata gcgcagttct tcttctgcaa cgcgagcgta gagccgattg
    65701 ttcttttcct tgatgatatc aaccttacca gtttcataaa gggcaacacc ttcgatacga
    65761 actttccccg gaatcaattt agccatattt tcacctttac cttatctttt tattatacca
    65821 tattttcgcc tatgaaaata gccttctagg aagacttttc tcctagaaga ctggattttt
    65881 aacgtttggc aaaagtagcc acaatccgct gacagacttc ctgcaacaga gatttgggca
    65941 tagctatatt gatgcgggca tggagacttc cttcctctcc aaaatccaaa ccacggttga
    66001 ggataacctt ggattcattt ctcaacaact cttgcaatgt ttcatcagtc aggtcatagg
    66061 ctgaaaagtc aagccaaatc aagtaggtac cttgcggttt catgaccttg attttagtct
    66121 cttttccaaa tagatctacc acataattga tgtggtcttc aaagacttgc ttgagttcct
    66181 ctagccaatc tttaccgtat cgataggcag cttctgtcgc caaataaccc aagcctgaaa
    66241 tttcatgctg attattggcc aacaggcgtt tctggaaagc cagtctcaac ttaggatttt
    66301 caatgactgc ataggaattt tttgttccag caatattaaa tgttttagtg gcactgctca
    66361 agacgatagc aaaatttttg aaggcaggat tgatggtatt gaaagactgg tgtttgtgac
    66421 caaagagggt caaatcttgg tgaatctcat ccgaaactaa caaaacaccg tgtttttggc
    66481 agagttggcc aatcttctcc aacacttctt tttcccaaac acgtccacca ggattgtgag
    66541 gattgcaaag aatatagagt ttaacctcct cttccaccaa atccttttca agttggtcaa
    66601 agtcaatctc aaacagacca tccttttcca ctaaggaatt agtaatcaat ctacgattat
    66661 tcaacttgac actgcgagca aagggtgggt agacaggcgt gttaattaaa accgcctcgc
    66721 cttcttttgt aaaggtttga atagctgttg agatggctgg taccacaccc tcgataaaga
    66781 caagagcctc tttgtcaaag ttgtaaccgt attgtgtagc ttcccacttt tgaacttcct
    66841 taattaagtc ttcactggca taggtataac cataaaccag ttggtctgcg taagtttgca
    66901 cggcttggcg gatttcaggc aagaccacaa agtccatatc cgctatccaa gctggtagaa
    66961 cttcactatc cgtttctgtt tctttccatt tataggtatg gtgccctaaa cggttgggca
    67021 ggcttgtaaa atcatatttt cccatctttg tcttatcctt ctaaggcttg gcgcaaatct
    67081 gcaatcaaat ctctagcatc ctcaatccca atagacaaac gcaagaggtc atctgtcaaa
    67141 ccataagaat ggcgtacttc tgctggaata tcagcatgag tttgagtcgt tggataagta
    67201 ataagacttt ccactccgcc caaactttcc gcaaaagaga agaccttgag actgttcaaa
    67261 atatgaggaa tgcgtgtttc atcggctact ttaaaggaaa tcatgcctcc acgaccagtg
    67321 tagagaactt ccttaactgc tggagaatcc ttcaaaaagg caaccacttc ttgggcgtta
    67381 gctgttgagc gctccatacg aagagacaag gtcttgagac cacgaagcaa ctggtagctg
    67441 tcaaatggag acaagactgc ccctgttgta ttaagattgt aaaaaagctt ctcgtatagt
    67501 tctaaactat tggtcacaac cactccagcc aagacatcat tgtggcctgc tagatacttg
    67561 gttgctgaat ggagaacgat atctgctcca tcttcaatcg gacgttggta gatagggcta
    67621 tagaaggtat tgtccaccac cactttggca cccttagcat gagccaattt tgctagtttt
    67681 tcgatatcaa attccaacat caagggattg gttggggttt cgatatagag aacatccaca
    67741 tccttttcta actcggcaat caactcttct tctgtattgg cataggtaaa atggaaacga
    67801 ccttcctgct ccacttggtt aaaccagcga aaagaaccac cgtaaagatc acgcactgcc
    67861 aagaccttac ttcctactgg aaagacgcta aaggccagta caatagctga catccctgag
    67921 ctagtcgcta gggcatagtc tgctgactca atagccgcaa agacttcctc agccttacta
    67981 cgagttggat ttttagtgcg cgtatagtca aacccagtag atcgaccaaa ctctggatgc
    68041 tgataggtcg ttgaaaaatg aagcggtgtc accaatgcac ctgtcgcttc atctgactta
    68101 atacccgcct gggccaaaat tgtgttaatg tgtaattcct tgctcataca atacctccaa
    68161 atctatagta actattgtac cacttatttt catcaactca ttttcttctt ttcaagagct
    68221 agttatagtt tcaaactata taaaaaggga gtttttcctg ctccctttaa tagactataa
    68281 aatggtgaat ctcaaaagac accttcactc tatcatttgc tcctgcacaa aacgagcata
    68341 acgctcatga ttttccagta gttccttatg agttcctgag ccagtgattt tcctctcctc
    68401 taagaagaaa atacaatcca catcttttac cgttgacaaa cgatgcgcta taatcacaac
    68461 cgtcttctcc tttaatgcag aatagaggat actgataatc gcatactcag aatacgcatc
    68521 aagattagca gtggattcat caaatataag aatttcagca tcttttaagt aggttctagc
    68581 tatttgaagt ctttggcttt gcccccctga caagaatcgt ccgcgttcac caacttcagt
    68641 atctagtccc tctttcatgg agcgaatctc atcacctagt gatactaagt ctagcacttt
    68701 catcaattca tcatcagtta ctaagcgatt caaaccgaga caaagattgt cacgaatact
    68761 gccagataag actgcattat tttgtgaaac ccaagcgatt ttacttctcc attcttttaa
    68821 gttaaaatca tatatacttg attgctccat tagaatatct cctgaaagcg gtttataaaa
    68881 ccgctctaac aaacgcacaa tcgttgattt tcctgatcca gatggtccaa caaaagcaat
    68941 ttttgcccct tgaaaattga acaagtaata tcctttaaga caggtcgatt ttcatcataa
    69001 ccaaaataga catggttaaa attcaaccct tgtcctgata ccgattttcc tccctcaaat
    69061 ttttctttag gaactgcaag caagttatcc agtgcaactg aagatccctt gctcctagaa
    69121 taaacagtta caaaattagc tatattacta ataggattaa gtaattgaaa gaggtaaatc
    69181 aaaaacgaaa ccaaggttcc cacagatata tatcctgcgc tgacccgata acccccatag
    69241 gttagcatca caactatagt cgcaaagata aataagagag caaacggggt ctcaaaagaa
    69301 gtaaccctat ctgatttcag tgaattgttt tgtacccttt caatacaatt atccaaaaca
    69361 tcctgtacac ttttctctgc ttggttagtc ttaattaatt catgttcttg aatcttttca
    69421 gtcaattgcc ctgttaaaaa tccgatttcc tcctgtaaac gacgactata cttttcactg
    69481 atattggaaa ggggcaagat aataaacatc atacaaggaa gagtgatgaa taaaagtaga
    69541 gaaagattcc aatcaagact aaataagact acaatggaac caagtaccat aactaaactc
    69601 agaataatat ttgggaaagt cgtaattaaa aactcacgaa tgacactcgt gtcattgaca
    69661 atggcagaag tcaactcccc actttggctc ttatcaaaga aggatttctc tgcataaatc
    69721 aacccctcta tcactttttt cctgattttt gctatctttt tttcacccga ttgactaaac
    69781 agatagtaac caatagaaga aaacaaggct tgaccaataa aaatcaaaaa cgattgaaat
    69841 actttggaac ctatattttc aatagaactc ccatctatta aaccctttaa gataagggga
    69901 agcaacaaag caagtagact agacagaaca aggaagaaac tccccataat caccttagta
    69961 tctactctta ataattttaa tttcataaat actccttata atatttcaac ggataaagtc
    70021 gggaataact caatttgagg ataaaatcta ataaatcttc ctataacaaa acgcataaca
    70081 tctaggattt tatatacctg atattatgcg tttttaagca caaagacttc ttacacaaac
    70141 ttatctacaa ttagatttta tttgacatgt tttgccaatt cttcttgggc ttttttattg
    70201 gattcttctt tttctttcaa ccatttttct ctggcttttg catattcgtc tgttgtgaca
    70261 atcttatctt gtactttgag gtatttatat gattcaaccc cttttgtacc ggttaaacca
    70321 taggcagcag caaatggtac ggttcttctc aatgatggtg ttcccccacg cgaaacactt
    70381 ggaagaacta aagaactatc aatcaaccaa gcttgaatat cagcatattt ctcataacgt
    70441 ttggctggat cttgctcttt attagcttct tccaacattt gagtatagac atccagtcca
    70501 acttccttag ccttgtcatt ggcttctcca ggctctagtc caagattttg tagaactcct
    70561 ccactattag tattaaaaat atcgagatag gttgacgggt cttgataatc aggtccccaa
    70621 ccgccatgat ataaatcata gtctttctga gcagctgttt gagcaaagta gcctgaactg
    70681 tcaaactcat ctgatgttaa ttgctgaatg tcaatcacta cattatcaga acctaaaaca
    70741 gattcaattg attgtttgat agaactaact ccttgtatgc ctactttatc tgttacttcc
    70801 acagtcttat ccaagtggat tgggaattga acaccctttg cttcgagttc tttcttagct
    70861 tccgcaaact tagccttggc tttctcagga ttgtagtaag ggtcttgacc atccgcaaag
    70921 ttgatacctt gccattcctt accatagttg accatcttag aggctacaac ttcaccaaag
    70981 tcttttccct tgatactgac aaagtttgga ggaaccacta ggttacgcaa aatctttgtt
    71041 gcaccttctt tcccttcaga ctgagcccca taagatgttc tgtcaaaagc aaaattgata
    71101 gcctgacgga agtttttatt gagaactgct tcctgagtcg atttcttttc aatgtcactt
    71161 gttttagaag tataattgta agacttccta tctaggttaa aattaaagaa atatgaagtt
    71221 gaattttgca tactatagat gatattgttt ttgtattttt ctttaatccc ttcatagctg
    71281 gagctgttag gaaaaagacg agccgtagta taagcaccag ctgtaaaatt acgttccagt
    71341 gattcttggt cgctaccatc atagtaggtc aatttcacat cgtctacaaa gacattctta
    71401 gcatcccagt aattagggtt tttcttatat tcaatagcag attttgagac aagtgctttc
    71461 atcaagaaag gtccattgta caaaatacta gatggatccg ccttcccaaa atcatcccct
    71521 tttgatttca ggaaatctgc attaacagga aaaagtatcg ttgcaagtgt ttttgaattc
    71581 cagtaaagtt ctggtttaac caaagtatat tgaaccgttt ggtcatcaag tgccttgaca
    71641 ccgacagttg aaaagtcgct tgttttacca gtgatatagt catccaaacc agcaacagag
    71701 tcctgcacta gata
//
LOCUS       DAVLIK010000004        67506 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLIK010000004 DAVLIK010000000
VERSION     DAVLIK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.004"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            5..92
                     /locus_tag="VXE87_000253"
     tRNA            5..92
                     /locus_tag="VXE87_000253"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Ser,seq:gct)
     gene            complement(218..1153)
                     /locus_tag="VXE87_000254"
     CDS             complement(218..1153)
                     /locus_tag="VXE87_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0841869.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1150..2010)
                     /locus_tag="VXE87_000255"
     CDS             complement(1150..2010)
                     /locus_tag="VXE87_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0841870.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2118..4280
                     /locus_tag="VXE87_000256"
     CDS             2118..4280
                     /locus_tag="VXE87_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0841871.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENQNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHTQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4372..5631
                     /locus_tag="VXE87_000257"
     CDS             4372..5631
                     /locus_tag="VXE87_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0841872.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5645..6511
                     /locus_tag="VXE87_000258"
     CDS             5645..6511
                     /locus_tag="VXE87_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0841873.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6525..7358
                     /locus_tag="VXE87_000259"
     CDS             6525..7358
                     /locus_tag="VXE87_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0841874.1"
                     /translation="MKQDERKALIGKYILLILGTVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7359..7439
                     /locus_tag="VXE87_000260"
                     /pseudo
     CDS             7359..7439
                     /locus_tag="VXE87_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7716..9158
                     /gene="gtfA"
                     /locus_tag="VXE87_000261"
     CDS             7716..9158
                     /gene="gtfA"
                     /locus_tag="VXE87_000261"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0841875.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFRDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9296..10489
                     /locus_tag="VXE87_000262"
     CDS             9296..10489
                     /locus_tag="VXE87_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0841876.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11176..13155
                     /locus_tag="VXE87_000263"
     CDS             11176..13155
                     /locus_tag="VXE87_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0841877.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNVDKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13222..14718
                     /locus_tag="VXE87_000264"
     CDS             13222..14718
                     /locus_tag="VXE87_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0841878.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14718..15644
                     /locus_tag="VXE87_000265"
     CDS             14718..15644
                     /locus_tag="VXE87_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0841879.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15653..16720
                     /locus_tag="VXE87_000266"
     CDS             15653..16720
                     /locus_tag="VXE87_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841880.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16731..17657
                     /locus_tag="VXE87_000267"
     CDS             16731..17657
                     /locus_tag="VXE87_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841881.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            18276..19085
                     /locus_tag="VXE87_000268"
                     /pseudo
     CDS             18276..19085
                     /locus_tag="VXE87_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            19097..19974
                     /locus_tag="VXE87_000269"
                     /pseudo
     CDS             19097..19974
                     /locus_tag="VXE87_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            19987..20790
                     /locus_tag="VXE87_000270"
     CDS             19987..20790
                     /locus_tag="VXE87_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0841882.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGRN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20823..21533)
                     /gene="treR"
                     /locus_tag="VXE87_000271"
     CDS             complement(20823..21533)
                     /gene="treR"
                     /locus_tag="VXE87_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0841883.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21718..23685
                     /gene="treP"
                     /locus_tag="VXE87_000272"
     CDS             21718..23685
                     /gene="treP"
                     /locus_tag="VXE87_000272"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0841884.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QCVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            23863..25488
                     /gene="treC"
                     /locus_tag="VXE87_000273"
     CDS             23863..25488
                     /gene="treC"
                     /locus_tag="VXE87_000273"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0841885.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25630..25878
                     /locus_tag="VXE87_000274"
     CDS             25630..25878
                     /locus_tag="VXE87_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0841886.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26085..26879
                     /gene="racE"
                     /locus_tag="VXE87_000275"
     CDS             26085..26879
                     /gene="racE"
                     /locus_tag="VXE87_000275"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0841887.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            26876..27847
                     /locus_tag="VXE87_000276"
     CDS             26876..27847
                     /locus_tag="VXE87_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0841888.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27823..28344
                     /locus_tag="VXE87_000277"
     CDS             27823..28344
                     /locus_tag="VXE87_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0841889.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28341..28802
                     /locus_tag="VXE87_000278"
     CDS             28341..28802
                     /locus_tag="VXE87_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0841890.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28793..29533
                     /gene="xerD"
                     /locus_tag="VXE87_000279"
     CDS             28793..29533
                     /gene="xerD"
                     /locus_tag="VXE87_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0841891.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29533..30261
                     /locus_tag="VXE87_000280"
     CDS             29533..30261
                     /locus_tag="VXE87_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0841892.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30280..30849
                     /locus_tag="VXE87_000281"
     CDS             30280..30849
                     /locus_tag="VXE87_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0841893.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            30836..31558
                     /locus_tag="VXE87_000282"
     CDS             30836..31558
                     /locus_tag="VXE87_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0841894.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31558..31800
                     /gene="yidD"
                     /locus_tag="VXE87_000283"
     CDS             31558..31800
                     /gene="yidD"
                     /locus_tag="VXE87_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0841895.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(32025..32990)
                     /locus_tag="VXE87_000284"
     CDS             complement(32025..32990)
                     /locus_tag="VXE87_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0841896.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQKVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33086..33838)
                     /locus_tag="VXE87_000285"
     CDS             complement(33086..33838)
                     /locus_tag="VXE87_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0841897.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(33835..34791)
                     /locus_tag="VXE87_000286"
     CDS             complement(33835..34791)
                     /locus_tag="VXE87_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0841898.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTHSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34781..35740)
                     /locus_tag="VXE87_000287"
     CDS             complement(34781..35740)
                     /locus_tag="VXE87_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0841899.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSILFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36163..36864)
                     /gene="galE"
                     /locus_tag="VXE87_000288"
     CDS             complement(36163..36864)
                     /gene="galE"
                     /locus_tag="VXE87_000288"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0841900.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37265..38329
                     /gene="pepA"
                     /locus_tag="VXE87_000289"
     CDS             37265..38329
                     /gene="pepA"
                     /locus_tag="VXE87_000289"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0841901.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38351..38647
                     /locus_tag="VXE87_000290"
     CDS             38351..38647
                     /locus_tag="VXE87_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0841902.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            39329..39772
                     /locus_tag="VXE87_000291"
     CDS             39329..39772
                     /locus_tag="VXE87_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0841903.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            39776..40540
                     /locus_tag="VXE87_000292"
     CDS             39776..40540
                     /locus_tag="VXE87_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0841904.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40555..41283
                     /locus_tag="VXE87_000293"
     CDS             40555..41283
                     /locus_tag="VXE87_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841905.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41276..42796
                     /locus_tag="VXE87_000294"
     CDS             41276..42796
                     /locus_tag="VXE87_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0841906.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43141..43947
                     /locus_tag="VXE87_000295"
     CDS             43141..43947
                     /locus_tag="VXE87_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0841907.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44113..44649)
                     /locus_tag="VXE87_000296"
     CDS             complement(44113..44649)
                     /locus_tag="VXE87_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0841908.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            44782..45672
                     /locus_tag="VXE87_000297"
     CDS             44782..45672
                     /locus_tag="VXE87_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0841909.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            45916..46269
                     /locus_tag="VXE87_000298"
     CDS             45916..46269
                     /locus_tag="VXE87_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0841910.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46270..47307
                     /locus_tag="VXE87_000299"
     CDS             46270..47307
                     /locus_tag="VXE87_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0841911.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(47353..48360)
                     /gene="galR"
                     /locus_tag="VXE87_000300"
     CDS             complement(47353..48360)
                     /gene="galR"
                     /locus_tag="VXE87_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0841912.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48524..49702
                     /locus_tag="VXE87_000301"
     CDS             48524..49702
                     /locus_tag="VXE87_000301"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0841913.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49721..51202
                     /locus_tag="VXE87_000302"
     CDS             49721..51202
                     /locus_tag="VXE87_000302"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0841914.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKAQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            51272..51676
                     /locus_tag="VXE87_000303"
     CDS             51272..51676
                     /locus_tag="VXE87_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0841915.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            51857..52621
                     /locus_tag="VXE87_000304"
     CDS             51857..52621
                     /locus_tag="VXE87_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEV0841916.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            52618..53079
                     /locus_tag="VXE87_000305"
     CDS             52618..53079
                     /locus_tag="VXE87_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV0841917.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(53130..54392)
                     /locus_tag="VXE87_000306"
     CDS             complement(53130..54392)
                     /locus_tag="VXE87_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0841918.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIFVASLLAIVLNAVLNHKKK"
     gene            complement(54392..54973)
                     /locus_tag="VXE87_000307"
     CDS             complement(54392..54973)
                     /locus_tag="VXE87_000307"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0841919.1"
                     /translation="MKLLEERILKDGHILDDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVLFKEADL"
     regulatory      complement(55373..55468)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(55851..56090)
                     /locus_tag="VXE87_000308"
     CDS             complement(55851..56090)
                     /locus_tag="VXE87_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0841920.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(56135..56233)
                     /locus_tag="VXE87_000309"
     CDS             complement(56135..56233)
                     /locus_tag="VXE87_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0841921.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            complement(56245..57072)
                     /gene="xth"
                     /locus_tag="VXE87_000310"
     CDS             complement(56245..57072)
                     /gene="xth"
                     /locus_tag="VXE87_000310"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0841922.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            57206..57662
                     /locus_tag="VXE87_000311"
                     /pseudo
     CDS             57206..57662
                     /locus_tag="VXE87_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            57734..58111
                     /locus_tag="VXE87_000312"
     CDS             57734..58111
                     /locus_tag="VXE87_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0841923.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVSLKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            58317..60062
                     /locus_tag="VXE87_000313"
     CDS             58317..60062
                     /locus_tag="VXE87_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0841924.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSVFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            60052..61803
                     /locus_tag="VXE87_000314"
     CDS             60052..61803
                     /locus_tag="VXE87_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841925.1"
                     /translation="MQNKQEQWAVLKRLMSYLKSYGLLIFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKVLILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            61976..62668
                     /locus_tag="VXE87_000315"
     CDS             61976..62668
                     /locus_tag="VXE87_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0841926.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNCRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            62711..63937
                     /locus_tag="VXE87_000316"
     CDS             62711..63937
                     /locus_tag="VXE87_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0841927.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            65067..67226
                     /gene="pfbA"
                     /locus_tag="VXE87_000317"
     CDS             65067..67226
                     /gene="pfbA"
                     /locus_tag="VXE87_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0841928.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYNIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            67210..67506
                     /locus_tag="VXE87_000318"
     CDS             67210..67506
                     /locus_tag="VXE87_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841929.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
BASE COUNT        19815 a        12409 c        15105 g        20177 t
ORIGIN      
        1 aattggagaa ttactcaaga ggctgaagag gacggtttgc taaatcgtta ggtcgggtaa
       61 ctggcgcaag ggttcgaatc ccttattctc cgttttaatg agagtttgta actctctttt
      121 ttatttttag agccaataaa acttcagatc cgtaaaactt aattgaatta ctaatctgaa
      181 gttattttta tatcgtttat attataattg tgttatttta cttccaacta ttgagagaaa
      241 tttcgccact atttagccag atttcttttc cgttatcaca ttgaactaaa agttttccat
      301 tttctgagat gtctttagca agtcccttgt agtctttttg ctctagtgtg aaagtgactt
      361 cttttcctag aatgaatgac tgttttttgt ataggtataa tagctcttct gctggtgttt
      421 cgaagaaagc acgccagatt tctatgatca attcattcct tgttatagga gctgtagctt
      481 taaataagct ggcagctttt tcttttaatt cctgagggaa gtctttaata gtgaaattga
      541 tacctactcc aataatgata tctgtgacta agccagtttc tacagaggtc attgcttcag
      601 taaggattcc tccaatttta tgattgttta gatagatatc attgacccat tttatgtcga
      661 catctattaa agttaggttc ttaatggctt tgtagacagc tccagctaca agtagtgtgt
      721 aggatggtaa tttgtcatag gggagatttg gtttaagatg gagtgtcata taaataccac
      781 cttgtggtga gtagaaggaa cgttgaaaac ggcctcggcc tgctgtttga taggaagcta
      841 gatagagggt atttgcttca tggcctaaat caattgcttc ttttgcatct agttgtgttg
      901 attttgtttc gggtttaaag ctgactttaa ttggaagatt ttcttctaga atctctggaa
      961 gaataaggtc accattcatc agtttatatc ctctattttt gatactatca atttcaatgc
     1021 cttcttgttc tagtcgcttg atggctttcc aaattgctgt tcggcttagg gatagttttt
     1081 ctgcgatttt ttctccgctg atatagtcgg tttctttaga taggatttgg tagacagctt
     1141 ggtaggattt cataatgttg cctttcttac tagttggtat tgagagtatt cttttcttgt
     1201 atgacttgga gtctgattaa agtattgttt ataagctttc gaaaaatgga gtggatctga
     1261 aaaacctacc gagtatgcaa ttaccttgat ggactcttgg gtattttcga gaagttgtct
     1321 agctcggtgc attcgaacgt agagtaggta ttctttgggt gataaggtat taaattcttt
     1381 gaatacgctt gataagtagc ttctgtgaac ggatagttct tttgctaaat cttgaattgt
     1441 aagtgattga ggatagtggc tatcaattaa tcgtttgcat tcaagataga gttggtgggt
     1501 tgatgaaata ttcttttttt tctgattggg agcaatagtt cccagatgaa acatcagttc
     1561 atgaagttgt cccatgatat ggagttgagc taattcactt gattttgtaa tctgagcgaa
     1621 gcggacaatg tctgagatga gttttgcagt agtctgggta tgacaagttt cagattggat
     1681 gagataggat tgatcagaaa tttgagaaag agcaaaataa tcaggggatt tccctccagt
     1741 gattcctaac cagtagtagg cccaaggttc tttactatct gcttgataaa aggttagttc
     1801 ctctggtttt aatagaaaga aatctccttc ttttaaatca acaattttac ccttgtaata
     1861 aaattttcct tgtcctttag taatgtaatg tagaacgtat gtatcacgaa tggctggacc
     1921 aaaagagtaa ttaggtgtgc attcctcata tccataaaag cttagggcaa ggtcgattgt
     1981 tccagtctgg tattctgaaa aaactaacat gtgctacctc ccacctaaca ttttaccata
     2041 ttcttgagac atttttctat tttggaaagc gatttcaggt gataaaatat aatcaataaa
     2101 gtgatgaggt gaagtaaatg ggagttagga tagagaataa tctattttat gttgagagta
     2161 aaaatctaag tttgattatt gaaaatcaaa atggctactt acttttgaaa catttaggaa
     2221 agactattaa gaactataaa ggttccaata gtgtttatga acgagaccat gccttttcag
     2281 gaaatccaac ggctactaat cgaaccttta gtttagatac tcagcgacag atttttggac
     2341 aacatggctt aggagatttt aggaaaccaa ccatacaggt tcagcatagt gtaactgaag
     2401 taacagactt tcgatttgta gaagcaaaga ttttaaaagg tcagaatggt ccacagggct
     2461 taccttctcc acatagcatg gacgatacag agactcttgt cttaatgtta gaagattcta
     2521 aggctcaact tagtctgact ttgtattata ctacttttaa taatgatgcg actattgcta
     2581 gctacagtaa attagataat aatagtaatc aggaagttgt catccataaa gatttttctt
     2641 ttatggctga ttttccagct gcagattacg aaatagtaac tctgcagggt gcttatgctc
     2701 gtgaaaagac tgttagacgt caacaggtag aacaaggaat cttttcgatt agctcaaacc
     2761 gaggtgcttc tggtcatact caaacaccag ctcttctact atgcgaacaa ggagtcacag
     2821 aggatgctgg gaatgtgttt gctattcaac taatgtatag tggcaacttt gaagcttttg
     2881 ttcaaaaaaa tcaattgaat gaagttcggg tggctattgg cattaatcca gaaaactttt
     2941 cttggaagtt agcccctgag gaatactttg aaacaccggt agctttagtg actcattcag
     3001 atcagggatt aactggtatt agtcatgaaa gtcagaattt tgtactgaag cacattatgc
     3061 taagtgaatt ttctaaaaaa gaacgtccaa ttctaatcaa taactgggaa gctacttact
     3121 ttgactttca gagagaaaaa ctgttagagt tagcagatga agctaagaaa gttggcattg
     3181 aactttttgt attagatgat ggttggtttg gcaatcgttt tgatgataat cgtgctttag
     3241 gtgattgggt tgttaatgag gaaaaactgg gtggaagtct agaaagtctg atttcagcta
     3301 tccatgaaag aggtttgcag tttggacttt ggttagaacc cgaaatgatt tctgtagata
     3361 gtgatttgta tcgtcgacat cctgactggg ctattcaggt tcctgactat gagcatactt
     3421 attctcggaa tcaattagta cttaatcttg ccaatcctca ggtagtagaa tacttgaaaa
     3481 gtgtcttaga tcaactccta tcttatcatg atattgatta cattaaatgg gatatgaacc
     3541 gcaatatcac taagctaggg aatggattaa cttatctaga gacacagatg caatctcatc
     3601 agtacatgct ggggctttac gaactcgttt cttatctgac agagaagcac agccatattc
     3661 tctttgagtc ctgctctggt ggtggtggac gaaatgatct tggtatgatg cgctatttcc
     3721 cacaagtctg ggctagtgat aatactgatg ccattgcacg tttaccaatt caatacggtt
     3781 catcctatct ctatccaacc atttctatgg gggctcatgt gtcagcagta ccaaatcatc
     3841 agatgggacg aatgacacca ttagaaacac gtggccttgt agcaatgatg ggaaatttgg
     3901 gatatgaact tgatttgaca aatttatcag atgaagagaa agctacgatt gctaatcagg
     3961 tgaacttgta taaagaatta cgaccagtag ttcagttagg acagcagtat agactaatta
     4021 atcctgatac tgcatccaat gaagcagctg tacaatttaa ttacggaaat caaacgattg
     4081 taacctacgt tcgcgtttta tctgttgtag agaccatgga aacaacttta aaattaaaag
     4141 atttggatga agagggacta tataaattac aggaaaatgg cgaagtttac tcaggtgcag
     4201 aactaatgta tgcgggctta actgttatct tatcccaagg agattttttg agtagacagt
     4261 atatttttag aaaactatga tatgtactga cctcaaaagt tagatttatt ctatctaact
     4321 tttgaggtgc agtttgataa gggtgtataa atttataaag gaggctttct aatggaatgg
     4381 tataaaaaaa tcggacttct tgcaactaca ggtttagctt tgtttgggct cggtgcttgc
     4441 tccaactatg gtaaatctgc ggatgacaca gtgaccatcg agtatttcaa ccagaaaaaa
     4501 gaaatgacca aaaccttgga agaaatcact cgtgattttg agaaggaaaa ccctaagata
     4561 aaggtcaaag tcgtcaatgt accaaatgct ggtgaagtat tgaagacacg cgttctcgca
     4621 ggagatgtgc ctgatgtggt caatatttac ccacagtcca tcgaactgca agaatgggca
     4681 aaagcaggtg tctttgaaga tttgagtaac aaagactacc tgaaacgcgt gaaaaatggc
     4741 tacgctgaaa aatatgctgt aaacgaaaaa gtttacaacg ttccttttac agctaatgct
     4801 tatggaattt actacaacaa agataaattc gaagaactgg gcttgaaagt tcctgaaacc
     4861 tgggatgaat ttgaacagtt agtcaaagat atcgttgcta aaggacaaac accatttgga
     4921 attgcaggtg cagatgcttg gacactcaat ggttacaatc aattagcctt tgcgacagca
     4981 acaggtggag gaaaagaagc aaatcaatac cttcgttatt ctcaaccaaa tgccattaaa
     5041 ttgtcggatc cgattatgaa agatgacatc aaggtcatgg acatccttcg catcaatggc
     5101 tctaagcaaa agaactggga aggtgctggc tataccgatg ttatcggagc cttcgcacgt
     5161 ggggatgtcc tcatgacacc aaatgggtct tgggcgatca cagcgattaa tgaacaaaaa
     5221 ccgaacttta agattgggac cttcatgatt ccaggaaaag aaaaaggaca aagcttaacc
     5281 gttggtgcgg gagacttggc atggtctatc tcagccacca ccaaacatcc aaaagaagcc
     5341 aatgcctttg tggaatatat gacccgtcca gaagtcatgc aaaaatacta cgatgtggac
     5401 ggatctccaa cagcgatcga aggggtcaaa caagcaggag aagattcacc gcttgctggt
     5461 atgaccgaat atgcctttac ggatcgtcac ttggtctggt tgcaacaata ctggaccagt
     5521 gaagcagact tccatacctt gaccatgaac tatgtcttga ccggtgataa acaaggcatg
     5581 gtcaatgatt tgaatgcctt ctttaacccg atgaaagcgg atgtggatta ggagtagaga
     5641 gactatgaaa aaagtattac aaaaatattg ggcatgggct tttgtggtca tccccctctt
     5701 gttacaagca attttcttct atgtgccgat gtttcaagga gccttttaca gttttaccaa
     5761 ctggacagga ttgacttata actacaaatt tgtcggctta aacaacttta agctcctctt
     5821 catggatcca aaattcatga atgcgattgg ctttaccgca atcattacga ttgccatggt
     5881 ggttggtgag attgcactcg ggatcttcat tgcgcgtgtc ttgaattcta aaatcaaagg
     5941 ccaaaccttc ttccgtgctt ggttcttctt cccagctgtt ttatctggtt tgacagtggc
     6001 tttgatcttc aagcaagtct tcaactacgg tcttccagcg attgggaatg cccttcatat
     6061 tgaatttctc caaaccagtc ttttagggac taagtgggga gcaatctttg cggctgtctt
     6121 tgtccttctt tggcaagggg tggctatgcc catcatcatc ttcctagctg gtttgcaatc
     6181 tattccaact gagattacag aggcagcaag gattgatggt gcgactagca agcaagtttt
     6241 ctggaacatt gaattgcctt acttgctacc aagtgtctct atagtcttta tcctagccct
     6301 aaaaggtggg ctgactgcct ttgaccaagt ctttgccatg accggtggtg gtccaaacaa
     6361 tgccacaacc tcacttgggc tcttggttta taactatgcc tttaaaaaca accaattcgg
     6421 ttatgccaat gccattgccg taatcttgtt cttcttaatt gtagtgattt cgatcatcca
     6481 attgagagta tctaagaaat ttgaaattta agaggagaag catgatgaaa caagatgaaa
     6541 gaaaagccct gattggcaaa tacattctat tgattctagg aacggttctg attttagtgc
     6601 cgctccttgc taccctcttt agttccttca aacccactaa ggatattgta gataatttct
     6661 ttggttttcc aaccaacttc acatgggaca actttagccg tctcttagct gatgggattg
     6721 gaggctatta ttggaactct gtcgtcatca ctgtcttgtc tttacttgca gtaatgatct
     6781 ttatccctat ggcagcctac tccatcgctc gcaatatgag taaaagaaaa gcctttacca
     6841 tcatgtatac cctcttaatc ctcggaatct tcgtaccttt ccaagtcatc atgattccga
     6901 ttacggttat gatgagtaaa ctcggtttgg ctaatacctt tggtttgatc ttgctctact
     6961 tgacctatgc gattccacag accctctttc tctatgttgg ctatatcaaa atctcgattc
     7021 cagaaagtct ggatgaagca gcagagatcg atggggctaa tcaatttaca acctatttcc
     7081 gcatcatctt cccaatgatg aaaccgatgc atgcgacaac catgatcatc aatgcccttt
     7141 ggttctggaa tgacttcatg ttgccactcc ttgtcttgaa ccgggattcc aaaatgtgga
     7201 ctctgccttt gttccaatac aactacgcag gccaatattt caacgactac ggaccaagct
     7261 ttgcctctta cgtggtcggc attatcagta tcaccattgt ctatctcttc ttccaacgcc
     7321 atatcatttc aggaatgagc aacggggcag tgaagtaata ctcaatgaaa atcaaagagc
     7381 aaactaggaa gctagccgca ggttgctcaa aacactgttt tgaggttgtg gatgaaactg
     7441 acgaagtcag taaccatacc tacggtaagg caacgctgac gtggtttgaa gagattttcg
     7501 aatagtataa gaagagctca tggaatctat agtctttgac acagaggaag agttcagctt
     7561 gttgataatt ctatgtagaa aacaagaaag tagtactttg tttatcacag tctatattag
     7621 tacgagtttg atgataaata gagatttaaa atgaatttta tttatgaagc cagatcatat
     7681 gagacttggc ttcaattaga aaaaggagag taatgatgcc aattcaaaat aaaaccatgt
     7741 tgattaccta ttctgatagc cttggaaata atcttaaaga cttatatgat aatttggaag
     7801 agcattttcg agatgctatt ggaggagttc accttttacc atttttccca tcaacaggtg
     7861 atcgtggatt tgcgccagtt gactacgacg aagtggactc agcttttggt gattgggagg
     7921 atgttaagcg tttaggtgag agatattatc ttatgtttga ttttatgatt aatcatattt
     7981 ctcgtcaatc caagtattat aaggactatc aagaaaaaca tgaagccagt gaatttaaag
     8041 ctctcttttt aaactgggat aagttttggc cagaaaaccg tccgacacag tctgatgtag
     8101 atttaattta caagcgtaag gatcgtgcac caaagcaaga gattgtgttt gaagatggtt
     8161 cagtggaaca tttgtggaat acctttggtg aagagcagat tgatcttgat gtgaccaaag
     8221 aagtaactat ggaatttatc cgtaagacca ttcagcactt ggcaagtaat gggtgtgatt
     8281 tgattcgtct agatgccttt gcttatgcag tgaagaaatt ggatactaat gatttctttg
     8341 tggaaccaga tatttgggat ttattggaca aagttcgaga tatcgctgct gagtatggga
     8401 cagagctttt acctgagatt catgaacact attcgattca gtttaaaata gcagaccatg
     8461 attactatgt ttatgatttt gctcttccaa tggtgacact ttatactctt tacagttcca
     8521 gaacagagcg tttggctaag tggttaaaga tgagcccgat gaagcaattt acgacgctag
     8581 atacccatga tgggattgga gtagtagatg tcaaggatat cctgaccgat gaggagattg
     8641 actatgcttc aaatgaactc tataaggttg gagccaatgt caaacgtaag tactctagtg
     8701 ccgagtataa caacttagat atctaccaaa tcaattcaac ctactattca gcgcttggag
     8761 atgatgatgt caagtatttt ctcgctcgtc taattcaagc ttttgcccca ggtattcctc
     8821 aggtttacta tgtgggtcta ttagcaggca agaatgactt gaaattatta gaagaaacta
     8881 aagaaggtcg aaatattaat cgtcattact atagcaacga ggaaatagca aaagaagtgc
     8941 aacgacctgt tgtgaaggcc cttctcaatc tattttcttt ccgtaaccgt tcagaagcct
     9001 ttgatctaga agggactact gagatagaga caccaacagc tcacagcatt gtaatcaaac
     9061 gtcaaaataa agataagtcc gtaacagcag tagtagaaat tgatttgcaa aatcagactt
     9121 atcgggtaat tgagaatgga gttgaagtat cattttgaag ccttgatatg gtggataaaa
     9181 tagggttttt attttggaaa acgtttcctt tgttttcaaa ttgctaaaaa agtggtacaa
     9241 tataggatag cttactatta tctgaatcag ctgatttgga gagaaaggat tcattttgaa
     9301 atcaataggc tttattgaaa agctgaaggg gttgtctagt aaagagctga ttttattggg
     9361 aattatccta agtatctttt taccctttta tctttttgta gttgtactct gtttatatat
     9421 tatcagtttg atttttacag gagacatgaa aagtattctt cagaaaatgg gggagcatcc
     9481 gatgctgctt ctttttctta gctatagtac tgttatatcc attcttgcac aaaattggat
     9541 gggtcttgtg gcttcagtag gaatgtttct atttactatt ttctttttgc actatcagtc
     9601 gattttatcc cataaattct ttcgattgat tttgcagttc gtcttgtttg gtagtgtctt
     9661 gtcagctgct tttgccagtt tagaacattt ccaaattgtg aagaaattta actatgcttt
     9721 tctttcaccc aatatgcagg tgtggcatca gaaccgggca gaagtgacct tctttaatcc
     9781 taattattat ggaattattt gttgtttctg tattatgatt gctttctatc tgtttacaac
     9841 gaccaagttg aattggttga aagtattctg tgtgattgca ggctttgtta atctctttgg
     9901 tttgaacttt actcaaaatc gaactgcctt tcctgctatt atcgctggag caattatcta
     9961 tctctttacg actattaaaa actggaaggc cttttggctt agtattgggg tcttcgcgat
    10021 tggtttgagt ttcctctttt ctagtgattt gggagttcga atgggtactt tagactcttc
    10081 tatggaagaa cgcatttcta tctgggatgc tgggatggcc ttgtttaagc aaaatccttt
    10141 ttggggtgaa gggccattga cctatatgca ctcttatcct cggatacatg ctccttatca
    10201 tgaacatgcc cacagtcttt atattgatac gattctgagt tacggaattg tgggtaccat
    10261 tttattagtt ttgtcttctg ttgctcctgt tcgcttgatg atggatatga gtcaggagtc
    10321 ggggaaacgt ccgattatcg gcctttatct atctttcctt acagtggttg ctgtgcacgg
    10381 aatttttgac ttggctctct tctggattca gtcaggcttt attttcttgc tagttatgtg
    10441 cagtattcca ttggagcatc gaatgttggt atcggacatg acggattaag ttttataagt
    10501 ttgaaatctt ctaccttggg taggagattt ttttatacga tgggcatgtc gtgcatctga
    10561 ggtgtaagtc ctctgtaggg atccactacc ggtgaataca atagcgctcc ccaagcctga
    10621 ctatcgtgag gtagcggatt aaaatggtct ggggatagat cgttttaagt ctgacgcagg
    10681 aaataagaat tgtcagagaa agcaatagtg aaatcgtagg ctatgaatag aaacgtgata
    10741 gcgaggagca tatagtggat aaggtagcga gaaattttaa agtataaaag atagtcttaa
    10801 tctatatatg taaatcacaa aagtaattga attcggaata aggttggtgt gaaaagacat
    10861 agtaaactga atcttgaata ctagaatgat acttctacaa tattgttata atttaatttg
    10921 aattccaaaa tcacattgtt ccgtccgtat ttcattttac tgtatgtctt cctaaactcc
    10981 aaagtttctg cgtcaaattt cctattttca ctgtagtctt tgacacttcg aacgacaatt
    11041 tgaatcatat attcaaaaaa aaatgaaaaa tttgtgccaa caagcctaaa tattctgaaa
    11101 atttgtttga tttttaatgg ataatgtgat ataatggttg tcaatctata attcacataa
    11161 acagaggagt agaaaatgaa aaaaaatcgt gtatttgcta cagcaggtct tgttttatta
    11221 gcagcaggtg tacttgcagc atgcagttct tcaaaatcat ctgattcatc agcccctaaa
    11281 gcttatggct atgtttatac agcagaccca gaaaccttgg actacctgat ttcaagtaaa
    11341 aatagtacaa cagtagtgac ttcaaatggg attgatggtt tattcactaa cgataattac
    11401 ggtaatcttg ctcctgcagt tgcagaggat tgggaagtct ctaaggatgg tttgacctac
    11461 acttataaga ttcgtaaagg ggttaaatgg tttacctctg atggagaaga atatgcagag
    11521 gtgacggcta aagatttcgt gaacggttta aaacacgcag cagataaaaa atcagaagct
    11581 atgtatttag ctgaaaattc ggttaaaggc ttggcagatt atctatcagg aacttcaaca
    11641 gatttttcaa cagttggtgt caaggcggtt gatgattata cgttacaata cactttgaac
    11701 cagcctgaac cgttctggaa ctctaagttg acctattcta ttttctggcc tctgaatgaa
    11761 gaattcgaaa catcaaaagg aagcgatttt gctaaaccaa cagatccgac atccttgctt
    11821 tataatggtc cattcttgtt gaaagggttg actgcaaaat cttctgtaga gtttgtaaaa
    11881 aatgagcaat attgggataa agaaaatgtc cacctagata ctatcaatct agcttactat
    11941 gatggatcag atcaggagtc gctagagcgt aacttcacta gtggagctta tagttatgcc
    12001 cgtctttacc ctaccagctc caactattct aaggttgcag aagaatacaa ggacaatatc
    12061 tattacacac aatcaggctc tgggattgct ggtctgggtg tgaatattga tcgccaaagt
    12121 tacaactata cttctaaaac tacagattca gagaaagtag ctactaagaa ggcattgctt
    12181 aacaaagatt tccgtcaagc cttgaatttt gctcttgatc gctcagctta ctcagctcaa
    12241 atcaatggta aagatggagc agctttagca gttcgtaatt tatttgtaaa accagacttt
    12301 gtttcagctg gtgagaagac ctttggtgat ttagtcgctg ctcaacttcc tgcttatggt
    12361 gatgagtgga aaggtgtgaa tttagctgat gggcaggatg gtttattcaa tgttgacaag
    12421 gccaaggcag agtttgcgaa agctaagaaa gctttagaag cagacggcgt tcagtttcct
    12481 attcatctgg acgttccagt agaccaagca tcaaaaaact acatatctcg tattcagtcc
    12541 tttaaacaat ctgtagaaac agttcttggt gttgaaaatg tcgttgttga tattcaacaa
    12601 atgacaagtg atgaattcct taatattact tactatgctg ccaatgcttc atctgaggat
    12661 tgggatgtat caggaggagt ttcatggggt ccagactatc aagacccatc tacttacctg
    12721 gatattttaa aaacaactag cagtgaaact acaaaaacat atttaggatt tgataatcca
    12781 aatagccctt cagtagttca agttggtttg aaagaatacg ataaattagt tgatgaagct
    12841 gccagagaga caagcgactt gaatgtccgt tatgaaaaat atgcagcggc tcaagcatgg
    12901 ttgacagata gttcactctt tattcctgct atggcttctt ctggtgcagc accagtgctt
    12961 tcacgaattg ttccatttac tggagcttct gcgcaaacag gctctaaggg gtcagatgtt
    13021 tacttcaaat atttgaaatt acaagataaa gtggtgacta aggaagagta tgaaaaagct
    13081 cgtgaaaaat ggttgaaaga aaaagctgaa tcaaatgaga aagctcaaaa agaattggca
    13141 agtcatgtga agtaaataat ttctaataga actttctctc catgaggaga aggttctttt
    13201 gggattttta aaggaaataa tatgaaaaaa tatattttta tgcgtgtttt gcggtcattg
    13261 gtttcgattt tcttagtaac gactttgacc tacacgatta tctatacctt ggttcctcga
    13321 aaattgattt tcaagcagga tcctaactat aataaaattg cgacaacggc tgataaacgt
    13381 gataactatg aaaatactgt gtttgagcgt atgggctaca ttgagtatta cgatactaaa
    13441 gagttgcaag aaaaggcaag tagcatggat tcttctgtaa cagtagaagc aaatgcgacc
    13501 aataaagcta tttatgaaaa gtacatcaat caattaggtc atggttggac tttgggagaa
    13561 tttactgaaa gtggtcaatt ctatgctact cgtgaaattc caatttttga acgtgttttt
    13621 cacttctatg ctaacttgat tgacattgac catacaaata aaatccaaga ccctgaaaat
    13681 ccagacttga aacgctacct tcgttttgaa aatgatccag ctatcggatg gtcattggtc
    13741 ggttcaggaa ctaaacataa atatctcttg tactttaaca gtcagttccc atttgttcat
    13801 caaaactttg tgaacttgaa tttaggtgac tcttacccaa cctatgctaa tacaccagtt
    13861 cttcaggtta ttactcaagg tcaaggacaa accaaaactg cccaagttca gttcccaaca
    13921 ggtaagaaaa cgtcttctgt aaatatttac tcaagaacct acaagtcacc tagtcaggct
    13981 gactctcgtg aagtagctag ctatgggaaa gatgatcctt atacagcgac tgaaagtaat
    14041 taccaatatc catctatgat tgtcagctct gctattactg gtttgattgg tttggttctt
    14101 gcctatgctc ttgccgtgcc acttggttca gccatggctc gtttcaagaa cacttggatt
    14161 gatagcctct caacagggac tttgaccttc ttgcttgctc ttccaacgat tgccttggtt
    14221 tacatcgttc gattgattgg atcatctatt gcccttccag attcattccc tatcttggga
    14281 gctggagatt ggcgttctta cgttttacca gcagtcatcc ttggtttgtt gggtgctcct
    14341 gttacagcca tttggattcg tcgttacatg attgacttgc aatctcaaga ctttgttcgt
    14401 ttcgctcgtg caaaaggttt gtctgaaaaa gaaatttcaa acaaacacat ctttaaaaat
    14461 gccatggttc cgctggtttc aggaattcct ggtgccatta ttggggttat cggtggtgca
    14521 acccttactg aaacagtctt cgccttccca ggtatgggta aaatgttgat tgactctgta
    14581 aaagcatcta ataactctat ggtcgttggt cttgtcttca tctttacatg tatttctatc
    14641 ttctcacgtc ttttgggaga tatttggatg actattattg acccacgtat taaattgact
    14701 gagaaaggag gcaaataatg tctacaatcg ataaagaaaa atttcagttt gtaaaacgtg
    14761 acgattttgc ctctgaaact attgatgcgc cagcatattc ttactggaaa tcagtgttta
    14821 aacaatttat gaagaaaaaa tcaactgtag tcatgttggg aatcttggta gccatcattt
    14881 tgataagttt catctaccca atgttttcta agtttgattt caatgatgtc agcaaggtaa
    14941 acgactttag tgttcgttat atcaagccaa atgcggagca ttggttcggt actgacagta
    15001 acggtaaatc gctctttgac ggtgtctggt tcggagctcg taactccatc ctcatttctg
    15061 tgattgcgac agtgattaac ttggttatcg gtgtttttgt cggtggtatt tggggtattt
    15121 caaaatcagt tgaccgtgtc atgatggaag tttacaacgt catctcaaac atcccacctc
    15181 ttttgattgt tattgtcttg acttactcaa tcggagctgg attctggaat ctgatttttg
    15241 ccatgagcgt aacaacatgg attggtattg ccttcatgat ccgtgtgcaa atcttgcgct
    15301 atcgtgactt ggaatacaac ttggcgtcac gtactttggg aacaccaacc ttgaagattg
    15361 ttgccaaaaa tatcatgcct caattggtat ctgttattgt gacaaccatg actcaaatgc
    15421 ttccaagctt tatctcatac gaagccttct tgtctttctt cggtcttgga ttaccgatta
    15481 cagtgccaag tttgggtcgt ttgatttcgg attattcaca aaacgtaaca accaatgctt
    15541 acttgttctg gattccattg acaacccttg tcttggtatc cttgtccctt ttcgtagttg
    15601 gtcaaaactt agcggatgct agtgatccac gtacacatag ataggagtag aaatgacaaa
    15661 agaaaaaaat gtaattttga ctgctcgcga tattgtcgtg gaatttgacg ttcgtgacaa
    15721 agtattgaca gccattcgcg gcgtttccct tgaactagtt gaaggagaag tattagcctt
    15781 ggtaggtgag tcaggatcag gtaaatctgt tttgacaaag accttcacag gtatgctcga
    15841 agaaaatggt cgtattgccc aaggtagtat tgactaccgt ggtcaggact tgacagcttt
    15901 atcttctcac aaggattggg aacaaattcg tggtgctaag attgcgacta tcttccagga
    15961 cccaatgact agtttggacc ccattaaaac aattggtagt cagattacag aagttattgt
    16021 aaaacaccaa ggaaaaacag ctaaagaagc gaaagaattg gccattgact acatgaataa
    16081 ggttggcatt ccagacgcag atagacgttt taatgaatac ccattccaat attctggagg
    16141 aatgcgtcaa cgtatcgtta ttgcgattgc ccttgcctgc cgacctgatg tcttgatctg
    16201 tgatgagcca acaactgcct tggatgtaac tattcaagct cagattattg atttgctaaa
    16261 atctttacaa aacgagtatc atttcacaac aatctttatt acccacgacc ttggtgtggt
    16321 ggcaagtatt gcggataagg tagcggttat gtatgcagga gaaatcgttg agtatggaac
    16381 ggttgaggaa gtcttctatg accctcgcca tccatataca tggagtctct tgtctagctt
    16441 gcctcagctt gctgatgata aaggggatct ttactcaatc ccaggaacac ctccgtcact
    16501 ttatactgac ctgaaagggg atgcttttgc cttgcgttct gactacgcaa tgcagattga
    16561 cttcgaacaa aaagctcctc aattctcagt atcagagaca cattgggcta aaacttggct
    16621 tcttcatgag gatgctccaa aagtagaaaa accagctgtg attgcaaatc tccatgataa
    16681 gatccgtgaa aaaatgggat ttgcccatct ggctgactag gaggaaggaa atgtctgaaa
    16741 aattagtaga aatcaaagat ttagaaattt ccttcggtga aggaagtaag aagtttgtcg
    16801 cggttaaaaa tgctaacttc tttatcaaca agggagaaac tttctcgctt gtaggtgagt
    16861 ccggtagtgg gaaaacaact attggtcgtg ctatcatcgg tctaaatgat acaagtaatg
    16921 gagatatcat ttttgatggt caaaagatta atggtaagaa atcgcgtgaa caagctgcgg
    16981 aattgattcg tcgaatccag atgattttcc aagaccctgc cgcaagtttg aatgaacgtg
    17041 cgactgttga ttatattatt tctgaaggtc tttacaatca ccgtttattt aaggatgaag
    17101 aagaacgtaa agagaaagtt caaaatatta tccgtgaagt aggtcttctt gctgagcact
    17161 tgactcgtta ccctcatgaa ttctcaggcg gtcaacgtca acgtatcggt attgcccgtg
    17221 ccttggtcat gcaaccagac tttgttattg cagatgagcc aatttcagcc ttggacgttt
    17281 ctgtacgtgc ccaagtcttg aacttgctca aaaaattcca aaaagagctc ggcctgacct
    17341 atctcttcat cgcccatgac ttgtcggttg ttcgctttat ttcagatcgt atcgcagtta
    17401 tttacaaggg tgttattgta gaggttgcag aaacagaaga attgtttaac aatccaattc
    17461 acccatatac tcaagccttg ctttcagcgg taccaatccc agatccaatc ttggaacgta
    17521 agaaggtctt gaaggtttac gacccaagtc aacacgacta tgagactgat aagccgtcta
    17581 tggtagaaat ccgtccaggt cactatgttt gggcgaacca aaccgaattg gcacgttatc
    17641 aaaaaggact aaactagtaa tggttttata atttccatgt caatttttat gggaattata
    17701 aaactttttt tgttggactg atttgaaaaa ctttgaaagc ttcctgaaag aattttcgaa
    17761 aaattttaaa aaattctgaa atattattga caggtgatga aaaaggtggt aggataggaa
    17821 gcatcaaaaa agaaagcaga aaaagaaatg aataagagac aagccgtaac tatgaatcaa
    17881 aacttttact ttagctactt tagatagtgt ttgtagacat gtcaccatgg atgcaaacag
    17941 ttcaagcaat ttgtttgtat ctatgtggct aagatttttg attgtggtcc atatagatga
    18001 atatctaaat ggactagcta agttgtaact tgttaggtta tttcaagtat ccgtttagat
    18061 agtatctagg cggttttttg ttttatcttt tctgagaagg agtttcatta tgaaagttgt
    18121 tcgaaaatca ctagccccct cttggtagtg gggctcctct tgacttctct gatcagtttg
    18181 catcagttga aggcagataa gaaaaagatg tctttcgtat cggtatttcg cagtttatta
    18241 cccaccagtc cttagacgct actagagaag gatttgtgga tgagctggcc aaacaaggct
    18301 atgttgaggg ggaaaatatt gagattgatt tgcaaaatgc acagggagaa caaagaaatc
    18361 taaaaacgat ttcccagcaa ctagcagaat ccagcgatgt cgttctagcc atcgcaaggc
    18421 cttctgctca gagcttggcc aatacgacgc aaacgacacc agttatcttt tcagctgtaa
    18481 cagacccagt cagtgccaag ttggttgagt caagagaaca tcctgggggc aatgtaactg
    18541 ggacaagcga tcagtcatca gatgccattt caacccaaat caatttgata aagaaagtgt
    18601 tgccaaaggc taaaacgatt ggaatcctct atactcagag cgagcccaat tcggttgttt
    18661 aaaaggatga agctaagcga cttctgaaag aaaaaggctt taccgttgtt gaaaaaacaa
    18721 tcttggacag taataacgtc aaggcggcag cagagagttt gatggcagag gtggatatgg
    18781 tttttgtccc aactgataat atcatttcgt caaccatgga aacagttaag caggtttcta
    18841 ttaaacacaa ggttccagta ttcggtggtt caacagaaat gattgctgtt ggtggcttgt
    18901 ataactacgg aaccaattat gaagaattgg gacggcagac agctcgcatg ctgattcgtg
    18961 ttttaaaagg tgagaaacca gaaaatatag cagttgagtt gcctgaaaaa ctggaattgc
    19021 ataccaatca agaaatggca gatgcattgg gaattgatat tagtaagtta gaaggcaagg
    19081 aataaggagg attaagatga attttgtgtt atctagttta tcagaaggtt tgttgtggtc
    19141 gattatggca attggggtct acttgacttt ccgtattttg aatattgcgg atatgactgc
    19201 tgagggagcc tttcctctgg gggcagcagt cgttgtatca cagatacagg caggggcaaa
    19261 tccttggctt gcgactttac ttgctttggt ggcaggtatg gtagcaggtc ttgtatcagg
    19321 aatgctccac accaatatga aaatcccagc tctcttgaca gggattgtga ccttgacagg
    19381 gctctattca atcaatatta aaattatggg cagtgtaccc aatctttcct tgggagattc
    19441 tgcaaccgtc tttaaacagt tggcgagctt gggtctgaca aatgaaggag ctgttttctc
    19501 acttagttta gtctgtctct tacttgtttg gtcttgaccc ttttgatgaa aacagagatt
    19561 ggtttggtct tgcgttcgac tggggacaat atcccgatga gtgaggccaa tggagtcaat
    19621 gtaaacacca tgaagattgt tggttacatg atttcaaacg gtttgattgc cctatgtggt
    19681 tccttgtttg cccaaaatga tggattttca gatgtgactt ctgggacagg aaccattgtt
    19741 gttggtttga gctcggaagt cttgatacac gacttgacca ttggaggcca cttattatcc
    19801 atcggaatcg gtgctattgt ttaccgtttg attattttaa atatctatga aattccaaat
    19861 ctagatcaaa acttggtacg tctctttaat gcaatcttgc tcgctttggt tttatttgca
    19921 ccagaattgc aaaagagatt aaagattcgt ggtctgaaat tgagaaatga ataggaggag
    19981 aaagttatgg caagtttgtt aacacttgaa aatattcaca agacatttga agcagggacg
    20041 gtcaatgaga accatgtcct caaaggatta gatttagagg ttgaagaggg agattttatc
    20101 tctgtgattg gtagaaatgg agcaggaaaa tccactttga tgaatatctt ggctggtaat
    20161 ctatcggtgg acgaagggga ccttctactg gcagggaaat ccattaaaca tctgagtgtc
    20221 agaaagagag ccaaggatat tgcccgtgtt tttcaagatc ctaagatggg aacagcttct
    20281 cgtttgacga ttgaggagaa tatggctatt gccttgagac gtgggcaaaa gagagggctt
    20341 ggttggggcg tgaaggagaa ggatagaatc cagttccaag aggccttgaa ggagttgaat
    20401 attggtcttg aaaaccgctt aaaagtagat actcaatatc tctcaggagg acaaagacag
    20461 gctttgaccc tagtcatggc agctctggtg aaactcaaac ttttgctttt ggatgaacat
    20521 actgcggcac ttgacccgaa aaccagtcaa atggtgatgg acttgacgca aaagattgtg
    20581 gagtaccatc agtggacgac tttgatgatt acccatgata tgaatcatgc gattgagtac
    20641 ggcaatcgtc tcattatgct ctatcaaggc aagatagtgg tggatgtcaa gggagaagag
    20701 aaaaagcatc tgacagttga agaccttatg catctcttcc agaaaaatag tggccaaagt
    20761 ctggtcagtg atgaattagt tttgggataa agaaaaaggc tgagatctgg tgtctcagtc
    20821 ttttatttct tgcgttttgc aaaatctaca aatctaaatt tttctaactt atggcgactt
    20881 tcggtaaact gaaattggcg cccgtcttgg agatagactt ttgatttaat cgaaacgaca
    20941 taagggtctt tgccaatgtc catgagaatc ttgtctcggt cgcttgagtg gtcaatggtg
    21001 atttccttct gagcataatc aataaggagt ttgaggccat tttctatata agaatagata
    21061 gactgctcag caatttggcg agtgagattt gggatgagtt ccatatccag atagtctgta
    21121 tccagaacgg ataccagatc atccaccaca cgctggcgga ccaccttcca aaccatccga
    21181 aactctggga aaccggttat cagtgaggat tttttatcaa taataatctt gtccagactg
    21241 accacgttgg ttttagagcg cagtccaagt tctttaacta gttcttggta gctggttagg
    21301 ttggatacag ggaaattgac ggtttcttct ttgacgactt gagaaccttg ccctcttatc
    21361 tttttgatca atccttcctc ttggaggaga gacagggcct ttcggacggt atcacgactc
    21421 acttgatatt gctccataag gtcgtgctcg ctaggaagga aatctccgac agcgtaagtc
    21481 tcgttttgaa tggtttcttg gatttgctta aataattgtt ggtatttctt cattttgcct
    21541 gcttaaatag gttttcagtc tagtttaatg aacacctgta tctattttac catacaagtg
    21601 ctagaaaatt tacaaaaaaa cacccttttt ataccaaaca agttgcagac aagtttggta
    21661 tcgtttacaa tatacttatc aaatcaaact tgctttgaca agtataagga gaatcaaatg
    21721 ggaaaatttg aacaagaagc caaagatctg cttcaggcaa ttggaggcaa agaaaatgtg
    21781 actgccgtaa ctcactgtgc gacacggatg cgctttgttt taggagatga taagaaggct
    21841 aatgttaaag ctatcgagtc aattccagct gttaaaggaa cttttacaaa tgcaggtcaa
    21901 tttcaggtaa tcattggaaa tgacgtgccc atcttttata atgattttac agccgtttca
    21961 ggtattgagg gtgtttccaa agaagcagcc aagtctgcag ctaagagtaa tcaaaacgtg
    22021 gtccaatgtg ttatgaccac tctggcggag atttttactc cgattattcc agccttgata
    22081 gtcggaggat tgatcctcgg tttccgtaat gtcttggaag gtgtccattg gtcgatgttg
    22141 gatggcaaga ccatcacaga atcctctcag ttttgggcag gggttaatca cttcctttgg
    22201 ttgcctggtg aagctatctt ccagttctta ccagtaggga ttacttggtc tgtttctcgt
    22261 aagatgggaa ccagccaaat tttgggaatt gttctcggaa tctgtttggt atcgcctcag
    22321 ttgctcaatg cctatgcggt tgcttcaacg ccagcagctg atatcgcggc aaactgggtt
    22381 tggaattttg gctattttac tgttaatcgt atcggttacc aagcccaagt tatcccagcc
    22441 ttgcttgcag gtttgagtct gtcttatctt gaaatcttct ggcgcaagca tatcccagaa
    22501 gtcatttcta tgatttttgt acctttcttg tcattgattc cagccttgat tttggctcat
    22561 actgttttgg gaccaatcgg ttggacaatt ggacaaggac tttcatcagt tgtcttggca
    22621 ggtttaactg gtccagttaa atggctcttc ggtgcaattt ttggtgccct ctacgctcca
    22681 tttgtcatca caggtctgca ccatatgacc aatgccattg atacacaatt gattgcggat
    22741 gctggtggca ctgccctatg gccaatgatt gctctttcta atattgctca aggctcagcc
    22801 gtgtttgcct attatttcat gcatcgccat gatgagcgtg aggctcaggt ttcacttcct
    22861 gcaaccattt cagcctatct cggtgttaca gaaccagctc tttttggggt taacgtaaaa
    22921 tatatttatc catttgttgc tgggatgact ggttcagccc ttgcaggcat gttatccgtt
    22981 acttttaatg taactgcggc ttctattggt atcggtggtt tgccaggtat tctctctatt
    23041 caacctcaat acatgctgcc atttgcagga actatgctag ttgcgattgt tgttccaatg
    23101 ctcttgactt tcttcttccg caaggctggt ctctttacaa aaacagaggg cgatacgaac
    23161 ttgcaggcag aattcgttgc tcaagaagaa gcagaatttg tgaaccatga accagtagaa
    23221 cttacttcgg tagaaattat cagcccacta actggccaag tgaaagaatt gagtcaagcg
    23281 acggatccta tttttgcatc aggtgtcatg gggcaaggtc tggtcattga accaagccaa
    23341 ggtgagttga cctctccagt taatgggaca gtgacggttc ttttccctac caagcatgcc
    23401 atcggcattg tctctgacga gggagttgaa ttgctcatcc acatcggtat ggatacagta
    23461 ggtcttgatg gcaaaggttt tgaaagtctt gtagtccaag gagatcacgt tacagttggt
    23521 cagcaactga ttcgttttga tatggatgtc attaaggctg caggtctggt gacagaaact
    23581 cctgttatca tcaccaacca agatgcttat acagcgacta ttcccggaac ttatccgaca
    23641 acgatccaag ctggagcatc tctcatggtc gctacacgaa tctaatactc ttcgaaaatc
    23701 tcttcaaacc acgtcagctc tatctgcaac ctcaaaatag tgttttgagc aacctgtggc
    23761 tagcttccta gtttgttctt tgattttcat tgagtataat tgaaatagca caaataggga
    23821 cggaagactg cttcctccct tttatcagaa aaggagaaac agatgacact tgataaagga
    23881 aaagtagtct atcaaatcta tccaaaatct tacaaagaca ccactgaaaa cggtattggg
    23941 gatttccgtg ggattatcga aaaaattccc tatttagcca aattaggtgt ggatatggtc
    24001 tggctcaatc cattctatcc aagccctcaa cgggataatg gttacgatat ttcagattat
    24061 atggcagtgg atcctctttt tggtgatatg gctgattttg aggaaatggt gtgtgtcggt
    24121 aaagagcaca agattgactt tatgctggac atggtactta atcattgttc gacagagcat
    24181 gaatggtttc agaaagccct agctggtgat aagtattatc aagacttttt cttcatccaa
    24241 gaccaaccaa cagattggca gtctaagttt ggtggttctg catgggcgcc tttcggggat
    24301 actgggaaat actatcttca cctatttgat gagacccagg ctgaccttaa ctggcgcaat
    24361 tccaatgtcc gtaaggagct tttcaaggtt gttaatttct ggcgcgacaa gggtgtcaaa
    24421 ggttttcgat ttgatgtgat caatttgatc ggtaaggacg aggtttcagt ggactgtcct
    24481 gaaaatgaag ggaagccagc ttatacagac aaacccatcg ttcataacta tttgcgtatg
    24541 atgaaccaag ccacttttgg atctgacgat agctttatga cagttgggga aatgtcttct
    24601 accaccatgg aaaactgtgt cctctattcg tcgcctgatc gtcaggaatt atccatgacc
    24661 tttaattttc atcacctcaa ggtggactat aaggatggac aaaagtggac cttggctccc
    24721 tttgattttg aagagttgaa gagtctttac catagttggg gtaaggaaat gagtgataaa
    24781 gacggttgga gtgccctctt ttggaacaat cacgatcaac cacgtgcctt gaaccgtttt
    24841 gtcgatattc aaaacttccg caaggaagga gccactatgc tagcagccag cattcacctg
    24901 tcacgtggga caccttatat ctacatgggt gaggaaatcg ggatgattga cccagactat
    24961 gattctatgg ctgattacgt ggatgtcgaa tcgcttaatg cctatcagat gctcctagaa
    25021 gaaggaaaga gtcagcaaga agccttccag attattcaag ctaagtcgcg tgataattca
    25081 cgcattccca tgcagtggga tgcttcggaa aatgcaggat tttcaacagg cactccttgg
    25141 ttgaaagctg gtaaatccta taaagacatc aatgtagaaa atgaaatcca gggtccgatt
    25201 tttaccttct atcaagactt gattcgactg cgtaaggaaa tgccaatcat ttcagaagga
    25261 agttacaaac cagcctttga agatagcaaa caagtctacg cttttgaacg ccagtttgag
    25321 gatcaaaagt tactagtgct caataacttt tatgctaaag aagtggaaat cgacttgcca
    25381 gcagtctacc aaaatggaca gattttgatt tcaaactatg aagatgcaga agtgtctgag
    25441 aaaattctac taaaacccta tcaaacactg gctatttatg taaattaaac ttagcaagga
    25501 gacctctttt tcagaaaagc agggttcttt ttgctgtcta ttccatcctt gaaagtgtag
    25561 aacaaactgg tcagggtggc tagtttgtgg tataatgaaa gggattcaaa aagaaacagg
    25621 agaaaaatga tggatttact tttagcaatt gtattgattg tgctagcttt tctaggagga
    25681 gctcttggag gaatgtactt ggttcgtaag caaatcgaaa aagaatttgc tgacaaccca
    25741 cgtttgaatg ctgaagcagt tcgtactctt ttgagtgcaa atggtcaaaa accaagcgaa
    25801 gctaaggtac aacaagttta ccaccaaatc atccgccaac aaaaggcagc ccttgctaac
    25861 aataaaaaga aaaaataaat aaggaaaagt ctgggatgaa agttccagac ttctcactat
    25921 gttggttatg gtttagggat gagacttttt ccttgcattc tattgatatt tgattatgat
    25981 taagagagag gtagttgaca ttctatcaag ctgtcggtca gttcgttcag tacaaggaat
    26041 cataatgaac gatcaatcag aaaaaagact agaaagaaga ctgtatggat aatcgaccaa
    26101 ttggtttttt ggattcgggt gtcgggggct tgaccgttgt gcgcgagctc atgcgccagc
    26161 ttccccatga agaaatcgtc tatattggag attcggcgcg ggcgccctat ggcccccgtc
    26221 ctgctgagca aattcgtgaa tatacttggc agctggtcaa ctttctcttg accaaggatg
    26281 tcaaaatgat tgtcattgct tgtaacactg cgactgcggt cgtctgggaa gaaatcaagg
    26341 ctcaactaga tattcctgtc ttgggtgtaa ttttgccagg agcttcggca gccatcaagt
    26401 ccagtcaagg tgggaaaatc ggagtgattg gaacgcccat gacggtacaa tcagacatat
    26461 accgtcagaa aatccatgat ctggatcccg acttacaggt ggagagcttg gcctgtccca
    26521 agtttgctcc cttggttgag tcaggtgccc tgtcaaccag tgttaccaag aaggtggtct
    26581 atgaaaccct gcgtcccttg gttggaaagg tggatagcct gattttgggc tgtactcatt
    26641 atccactcct tcgccctatt atccaaaatg tgatggggcc aaaggttcag ctcatcgata
    26701 gtggggcaga gtgcgtacgg gatatctcag tcttactcaa ttattttgaa atcaatcgtg
    26761 gtcgcgatgc tggaccactc catcaccgtt tttacacaac agccagtagc caaagttttg
    26821 cacaaattgg tgaagaatgg ctggaaaaag agattcatgt ggagcatgta gaattatgac
    26881 aaataaaatt tatgaatata aggatgacca ggactggtat gttgggtctt atagtatttt
    26941 tggtggcgtt aacagtttga gcgactataa gacagatttt cctctgtttg aattctccaa
    27001 aatatttgga gatgaagagt atggtttccc gctttcagtt actgttttac gctatggttc
    27061 tacctaccgt ttgttctcct ttgtggtaga catgcttaat caagaaatgg gacgaaactt
    27121 ggaagttatt caacgtcatg gggccctgct cttggttgaa aatgggcaac tcttgtatgt
    27181 agaattgcct aaagaagggg tcaatgttca tgatttcttt gagacaagca aggtcagaga
    27241 aaccttgttg attgcgactc gtaacgaagg taaaaccaag gaattccgag ctatctttga
    27301 taagttaggc tacgatgtgg aaaatcttaa tgactaccct gacctgcctg aagtagcaga
    27361 aacaggtatg acctttgaag aaaatgcccg ccttaaggca gaaaccattt ctcaattaac
    27421 gggcaagatg gttttggcag atgattctgg tctcaaagtc gatgtccttg gtggcttacc
    27481 aggcgtctgg tcagctcgtt tcgcaggtgt gggagcaact gaccgtgaaa ataatgccaa
    27541 actcttgcac gaattggcca tggtctttga actcaaggac cgctcggctc agttccacac
    27601 aaccctagtc gtagccagcc caaataagga aagtttagtt gttgaagcag actggtcagg
    27661 ttatattaac tttgaaccta agggtgaaaa tggctttggc tatgatcccc tcttccttgt
    27721 aggagagaca ggtgagtcat cagctgaatt aaccctggaa gaaaaaaata gtcaatctca
    27781 ccgtgcctta gccgttaaga aacttttgga ggtatttcca tcatggcaaa gcaaaccatc
    27841 attgtaatga gcgattccca tggcgatagc ttgattgtgg aagaagtccg tgatcgctat
    27901 gtgggcaaag tcgatgccgt ttttcataac ggcgattctg aactacgtcc ggattctcca
    27961 ctttgggagg gcatccgcgt tgttaaaggg aacatggact tctacgccgg ctacccagaa
    28021 cgtctggtga ctgagcttgg ttcgaccaag attatccaaa ctcatggtca cttgtttgac
    28081 atcaatttca actttcaaaa gttggactac tgggctcagg aggaagaggc cgctatctgc
    28141 ctctatggtc acttgcatgt gccaagtgct tggttggaag gcaagatcct ctttctaaat
    28201 ccaggttcta tcagtcaacc acgaggtacc atcagagaat gtctctatgc tcgtgtggag
    28261 attgatgata gttacttcaa agtggacttt ttgacacgag atcacgaggt gtatccaggt
    28321 ttgtccaagg agtttagccg atgattgcca aggagtttga gactttcttg ttggggcagg
    28381 aggaaacttt tttgacccct gctaaaaatc tagctgtgtt gattgatacc cacaatgcgg
    28441 atcatgcgac cctcttgctc agtcagatga cctatacccg tgttcccgtt gtgacagatg
    28501 aaaaacagtt tgttgggacg attggactca gagatattat ggcttatcag atggagcatg
    28561 acttgagcca agaaatcatg gcggatacgg atatcgttca tatgacaaaa acggacgtag
    28621 cggttgtttc gcctgatttc accattacgg aggtcttgca caagctagta gatgagtcct
    28681 tcttaccggt tgtggatgca gagggtattt tccaagggat tattacgcgc aagtccatcc
    28741 tcaaggccgt taatgccctc ttgcatgact ttagtaagga atatgagatt cgatgccaat
    28801 gagagacagg atttcagcct ttttagagga aaagcagggc ttgtctgtca attccaagca
    28861 gtcctataag tatgatttgg agcaattttt agacatggta ggtgagcgga tttctgagac
    28921 cagtctcaag atttaccaag cccagctagc caatctaaaa atcagcgccc agaagcgaaa
    28981 gatttcggcc tgtaaccaat ttctatactt tctctatcaa aaaggagagg tggacagctt
    29041 ttaccgcttg gaattagcca aacaagctga aaagaagacg gaaaagccag agattctata
    29101 cctagactct ttttggcagg aaagcgacca tccagagggc cgcttgctag cgctcttaat
    29161 cctagaaatg gggcttttgc ccagtgagat tttagccatc aaggttgcgg acatcaatct
    29221 ggattttcag gtgttgcgaa tcagcaaggc ttcccaacag aggattgtca ctattcccac
    29281 ggccttgctt tcagaattgg aacccttgat ggggcagacc tatctttttg aaagaggaga
    29341 gaaaccctat tctcgtcagt gggcctttcg tcagttagaa tcttttgtca aggagaaagg
    29401 ttttccatcc ttatcagctc aagtcttacg tgaacagttt attctaagac aaatagaaaa
    29461 caaggtcgat ttgtacgaaa ttgcaaaaaa attaggatta aaaacagtcc tgaccttaga
    29521 aaaatataga taatggatat taaattaaaa gattttgaag gacccctgga cttgctcttg
    29581 catctggttt ctaagtacca gatggatatc tacgatgtgc ccattacgga agtcatcgaa
    29641 cagtatctag cctatgtctc aaccctgcag gccatgcgtc tggaagtgac gggtgagtac
    29701 atggtcatgg ctagtcagct catgctgatt aagagtcgta aactccttcc gaaggtagca
    29761 gaagtgacag acttggggga tgacctggag caggacctcc tctctcaaat cgaagaatat
    29821 cgcaagttca agctcttggg tgagcacttg gaagccaagc accaagaacg ggcccagtat
    29881 tattccaaag cgccgacaga gttgatttac gaagatgcgg agcttgtgca tgacaagacg
    29941 accattgacc tctttttggc tttttcaaat atcctagcca agaaaaaaga ggagtttgca
    30001 caaaatcata cgacgatctt gcgggatgag tataagattg aggacatgat gattatcgtg
    30061 aaagagtcct tgattggacg agatcaattg cgcttgcagg atttgttcaa ggaagcccag
    30121 aatgtccaag aggtcatcac cctctttttg gcaaccctag agttaatcaa aacccaggag
    30181 ctgatcctcg tgcaagagga gagttttgga gatatctatc tcatggaaaa gaaggaagaa
    30241 agtcaagtgc ctcaaagcta gacttgatag agaggaaaga tgagtacttt agcaaaaata
    30301 gaagcgctct tgtttgtagc gggtgaagat gggattcggg tccgccagtt agctgaactc
    30361 ctctctctgc caccgacagg catccagcaa agtttaggaa aattagccca gaagtatgaa
    30421 aaggacccag attccagttt ggctttgatt gagacaagtg gtgcttatag attggtgacc
    30481 aagcctcaat ttgcagagat tttgaaggaa tactctaagg cgcctatcaa ccagagcttg
    30541 tctcgggctg cccttgagac cttgtccatt attgcctaca aacagccgat tacgcggata
    30601 gaaattgatg ccatccgtgg ggttaactcg agtggagcct tggcaaagtt gcaggctttt
    30661 gacctgataa aggaagacgg gaaaaaggaa gtattggggc gccccaacct ctatgtgact
    30721 acggattatt tcctagatta catggggata aaccatttag aagaattacc agtgattgat
    30781 gagcttgaga ttcaagccca agaaagccaa ttatttggtg aaaggataga agaagatgag
    30841 aatcaataag tatattgccc acgcaggtgt ggccagtagg agaaaagcag aagagctgat
    30901 taagcaaggc ttggtgacgg ttaacggcca agtggtgcgt gaactagcaa ccactatcaa
    30961 gtcaggcgac aaggtcgaag ttgaaggtca acctatctac aacgaagaaa aggtctacta
    31021 tctgcttaac aaaccacgcg gtgtgatttc cagtgtgaca gatgataagg gtcgcaagac
    31081 ggttgtcgac ctcttgccca atgtcaaaga acgtatttac cctgtgggtc gtttggactg
    31141 ggatacatca ggtgtcttga ttttgaccaa tgatggggac tttacagacg agatgattca
    31201 ccctcgtaat gagattgaca aggtttatgt cgcgcgtgtt aaaggtgtgg ccaataagga
    31261 caatctccgc cccttgaccc gtggtcttga gattgatggt aagaaaacca agccagctgt
    31321 ttatgaaatt ctcaaagtgg acccagtcaa aaatcgctct gtggtgcagt tgaccatcca
    31381 tgaagggcgt aaccatcagg ttaaaaagat gtttgaagct gttggtctcc aagtagataa
    31441 gttgtctcgg actcgtttcg gacacctaga cttgacagga ctccgtccag gagaatcccg
    31501 tcgtcttaat aaaaaagaaa tcagccaact acacaccatg gctgtaacta agaaataatg
    31561 aaacgaattt taatagcgcc tgtgcgcttt taccaacgtt ttatctcacc agtctttcca
    31621 ccctcttgtc gctttgagct gacttgttcc aactacatga ttcaggctat tgaaaaacat
    31681 ggttttaagg gggtattgat gggcttggct cggattttac gttgtcatcc ctggtcgaaa
    31741 acaggtaagg accccgttcc agaccacttt tcccttaaac gaaatcaaga aggggaatga
    31801 ggtggggtaa atagatttca aaatgataaa aacgcatcct atcaggtttg agtgaacttg
    31861 ataggatgcg ttttagaatg tcaaaatttt atactcttcg aaaatccctt caaaccgcgt
    31921 cagctttcat ctgcaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt
    31981 tgctctttga ttttcattga gtattaaatt gagtttgaag tggcttattt caaagctttt
    32041 tgtatgtctt caatcatgag ttttgttgat tcaagtccgc ctccgcttag ataccagagg
    32101 tctggtgtta gttggataat cttaccattt ttagcagcag gtgtttcagc gataagggca
    32161 ttttctagga caccgtcgtt gctagagttg tccccaccga tggcaagggt acggttgatg
    32221 acaaagagga tgtcagggtt gatttctttg acactttcaa agctgacttc ttgtccgtgg
    32281 cgtgagtctt caaatgttgt atcagttggt ttgaatttca aggtttggta caagaaagag
    32341 aaacgagatt tggcaccaaa ggctgccatt tttccttcat taaggaggat cgcaagggcc
    32401 tttttgtcag agctttcatt tttagtagcg actttttgga tgctcttgtc tagcttggcc
    32461 aattcttcct tggctttctg tgtaccagtt tcgccgaagg cacttgctaa ggattcgata
    32521 ttagccttgg tagaagtcca gtagtcgtcc ttgcttgctt ggaagagaac ggttggggcg
    32581 atttctttga atttgtctac gaatttttgt gtacgtggtg aagcgataat caaatcaggc
    32641 tcaagggcgg cgatagcttc taaatcaggt tctttcatag aaccaacatt tttgacagtt
    32701 cccactaggt cttttagata agtcggaaca gtttttgtag gcattccgac gatatttttt
    32761 tcaaatccta aagcgcgaat agtatccgca gcgccgaggt caaaggtcac aatcttttca
    32821 ggaactttgg aaagtttgac ctcgtccagt gaacttttaa tggttacctc tgttggagca
    32881 gagctactgg tctctgtctg actagtgctt gagtttgtac tacatgcacc aagtaggagc
    32941 aagaagctgg ccactagggc agtgaaataa agtttaaggg atgttttcat aatttctcct
    33001 ttttaaaatg tgataacgat ttagggagtc tcttaatctt attgactaag agactgaagg
    33061 ttctctaact tgagctttta tgttactagc tatagataca gatctttttg tcattgatat
    33121 cagctagcgt gatgggaatc tcataaagtt gactgagcag gtcagcctgc atgatttgat
    33181 cggttcttcc cttgctaaag acctggccgt ccttgaaggc gacaatttca tctgcatact
    33241 gactggccat gttgatatcg tggaggacga tgataatggt cttgccgagt tcctccacca
    33301 gtcgtcgaag aatctgcatc atgctgacgc tttgcttgat atcgagattg ttgagtggtt
    33361 cgtccagcaa gataaagtcc gtatcctggg ccagtaccat agcgataaag acgcgctgga
    33421 gttgcccccc tgacaggcta ttgatgtagc ggtcttttaa gttggtcagt tccaaatagt
    33481 tcagagtttc tcggattttt tcccagtctt ctgatctaag tcgacctcgg ctgtagggaa
    33541 aacgtccaaa actgaccagt tcttcaacag tcaatttggc ttggtaattg attttctgtt
    33601 ttaggatggt tagttcttgg gccagttctt gcgaattcca gctctcgatt tcacgtcctt
    33661 tgatactgag aactccctga tctttcttgg ttagtctgct catgatggag aggagagtcg
    33721 attttccagc accatttgga ccaataaagg ctgtcagttt ttgaggactg acttcaagcg
    33781 aaatgccttg caaaatatcc tgtttttgaa tggatttgtc aatgttttcc agtttcactg
    33841 acgagccctc ctatatagta agataaagaa taagaagcca cccacactct caatgatcat
    33901 actgatacga atttccagtg caaagactcg ttcaatcaag gcttgcccca aggttaagct
    33961 aataaatcca accagaatgg ccactataaa gagtaacttg tgctgatagt ctttgacaat
    34021 caggtaggtg aggttggcca gcataaagcc gaagaaggcc ataggtccta ccaaggcagt
    34081 ggccgttgag gtcaaaagca cgattcccca gaggagctct ttctgttctt tttcaacatc
    34141 gagtcccaat atctgagccg tttctctttg caggtgcaag acatctagaa cgactgcttt
    34201 tcgaaagaaa aagattgtca aagcgaggat gatcagagaa ccgatggcta ggatggaagt
    34261 gttaagatgt tgaaaggagg caaaaagact attttgcagt ttatcgtatt cgtttggatc
    34321 cattaggact tgaaggaagg tgctgatatt tcgaaagaga cttctgagcg ctagacagat
    34381 cagcaggatg aagaccaggt cttgcttcat cagtgtcttc aagtaacctt gtaaggcgag
    34441 aaagaagagg gactggacaa gaagtaagac taggaattct aagatagggg atttgccaag
    34501 ttgaagaaac ttgctttcaa aaaccagtag tagggtttgt agtaggacgt agaaggattc
    34561 aattcccaaa atactatgcg tcaggaagcg attttccgtc agggtttgaa aactaatggt
    34621 cgaaatccca gtcgcgatgg ctaccaagag ataaacgatg atcttttggg aacgcaactt
    34681 ccaagcaaag gctgacaagt gagtgatggg ccaaaagtag agaagacaag ctccgatggc
    34741 aagaataatg agaatccaga agagcttggt atgtttgctt ttagtctgca tcttttcgtc
    34801 cccctctcca gagaagtagg ataaagacga gactaccgat gattcctagc aagagactga
    34861 cagacaactc atagggccta atcagaactc gggataggat atcgcaagcc agaactagat
    34921 tggcaccaac cagtgcgacc atgagtttgg tttgacttag attatctcca tagcgcttgc
    34981 gaacaagatt gggaacgata actccgagaa atggtaagcc acccacggta atcatggtga
    35041 cgcttgtcgt tagcgccacc agaaagaggg ccagtttttc aagtagggag taggaaatcc
    35101 ccaaactctc gctggtttct ttccctagat tcatgatggt gaaggtttgg gataatttcc
    35161 aaacggttat caggatgatg aggcctaaga agagccactc atactgatgg gtctgaatca
    35221 tggagaagga gccctgggtc caggcagtca tactctgaac cagattgaaa cgataggcga
    35281 taacttctgt gactgagccg ataatcccgc tatagatgat cccaatcaga ggcaacatcc
    35341 acctttcctt tacagtaaaa atggtcataa aggctaggaa gaagagggtg aataggatgg
    35401 atgaaacaaa agcgaagagc atcttttggg tcagactagc cgatggaaag acaaaaaggc
    35461 tcagcaccat tcccagtttg gcggcttcag tcgttccaac tgtactcggt gcagcaaact
    35521 gattttgggt aatagtctgc atgagaaggc ctgccatact catactagag gcagtcagga
    35581 gaatactgat agttcttggg agacgggact cttgaaagag gagccaggtc tgctggtcga
    35641 aatcaaatag ctttccccat gaaaaatcac tggtcccaat gctaatagag agaaagacta
    35701 ggagtagaag taagccaatt aaataatgag aaagtttcat accccgtcct ttcatgtaga
    35761 tttggtatcg aaagatacct gcggatataa atgtaacatt atttttctaa tctgtcaata
    35821 aaatttctga caatttaata aatacaacaa ggagagagca acaagacttt ctcctttgtt
    35881 atcctattct aaaatgtttt taccttaatc tgataaaata atatcttcga gggagtagct
    35941 agccgtccaa tcaagatatt gtttagcttt tgaagcatct gctaggacac tggctgggtc
    36001 actagcacgt cgagcaacaa tctcgtgtgg gattttttaa tttagtaatt cttcagcagt
    36061 tttaaagatt tctttgatag tatagccttt tttagttcct aagttaaaga tttgagaaga
    36121 actgtcttct tgaaataggt agttcattcc tttaacatga gcctatgcaa ggtccaagac
    36181 ataaatgtaa tctcgaatac atgaaccgtc acgtgtatcg tagtcatctc caaatatttt
    36241 taagctatca ttttgtccca atgcggtctt gttgatattt ggaatgatgt gagttggatt
    36301 tttcacacgc agaccgtttg aagcatccat ttcagcccca gcaacattaa agtaacggaa
    36361 aataacatat ttccagtcgt agcgattggc catccagtaa atcattcgtt cgcccatcag
    36421 ttttgtctct gcataagggt tgacagggtc gagcagggta tcttcagtca ccggcttgtc
    36481 aatacagtta tttccataga gagaagcagt cgaagagaac atgatttttt gaatgccaac
    36541 ttcagataag actttgagaa cttggttcat accagcaacg ttggcagtga agtatttact
    36601 tggattttca atactttcgc tcacaacaat ttcacctgca caatggagga cagcatcaat
    36661 ctgattttct tctaagtaag cctttaaggc gctagcatca taaacatcca gttctttaaa
    36721 gctagcacga ctatccacag ccgctcgatt tcctgtggag agattatcga ggacatgcac
    36781 cttatagcca gcatttaaaa gagctttaac ggtatgggag ccaatgtagc tagtcccacc
    36841 tgtaacaaga attgttttgg tcatgatttt ttccttttct agttttgtac tatagtaaat
    36901 tgaaataaga tatgaacaac tctattagga aagtcaaatt aatttctaga aatgtttcag
    36961 cagctacagc gtactattcc aaactcaacc aactatatat ttaaagaaag aagaaaggga
    37021 agtcaactat tttctgtaaa tttcatgaaa aatccaaaca actttgatgg tgtattgttt
    37081 ttttgtttgg aaataaatat tcgagttaat tttggaatgt ttactagatt ttgcactaca
    37141 tgcaagagaa tactatcctt ttctaagata gagcaggact aagatactaa cttagaaatc
    37201 caccttccca ctatccttct cctataaaaa gtggtaaaat ggatgaaaga aagaaggaac
    37261 tgaaatgaca acattatttt caaaaattaa agaagtaaca gaacttgctg cagtctcagg
    37321 tcatgaagcg cctgtccgtg cttatcttcg tgaaaagttg acaccgcatg tggatgaagt
    37381 ggtgacagat ggcttgggtg gtatttttgg tatcaaacat tcagaagctg tggatgcacc
    37441 gcgcgtcttg gtcgcttctc atatggacga agttggtttt atggtcagcg aaatcaagcc
    37501 agatggtacc ttccgtgtcg tagaaatcgg tggctggaac cccatggtgg ttagcagcca
    37561 acgtttcaaa ctcttgactc gtgatggtca tgaaattcct gtgatttcag gttctgttcc
    37621 tccgcatttg actcgtggaa aggggggacc aaccatgcca gccattgccg atatcgtttt
    37681 tgatggtggt tttgcggaca aggctgaggc agaaagtttt ggcatccgtc ctggtgatac
    37741 catcgtacca gatagttctg caattttgac agccaatgaa aaaaatatca tctcaaaagc
    37801 ttgggataac cgctacggtg tcctcatggt aagcgagcta gctgaagctt tatcaggtca
    37861 aaaactcggc aatgaactct atctgggttc taacgtccaa gaagaagttg gtctgcgtgg
    37921 cgctcatacc tctacaacca agtttgaccc agaagtcttc ctcgcagttg attgctcacc
    37981 agcaggtgat gtctacggtg gtcaaggcaa gattggagat ggaaccttga ttcgtttcta
    38041 tgatccaggt cacttgcttc tcccagggat gaaggatttc cttttgacaa cggctgaaga
    38101 agctggtatc aagtaccaat actactgtgg taaaggcgga acagatgcag gtgcagctca
    38161 tctgaaaaat ggtggtgtcc catcaacaac tatcggtgtc tgcgctcgtt atatccattc
    38221 tcaccaaacc ctctatgcaa tggatgactt cctagaagcg caagctttct tacaagcctt
    38281 ggtgaagaaa ttggatcgtt caacggttga tttgattaaa cattattaaa ccataaggga
    38341 ggtggtaggg atggtagaac caaacctaga aagccttata aaagatcttt acaatcatgc
    38401 tcgacatgat ttgagtgaag atttagttgc tgctctccta gagactacta aaaaactgcc
    38461 tactacaaat gagcaattgc aggcagttcg tctctcaagc ctggtcaatc gtgaattgct
    38521 cctaaatccc aaacatccag cacctgagtt gctcaacttg gctcgctttg tcaaaagaga
    38581 agaagccaag tacagaggaa ctgcgacttc tgcgcttatg tatgaggaac tttttaaaat
    38641 gctttgattc cattgtggat caaagcattt tttataagac ctatctcgtg agcgttcaaa
    38701 tagtagtaac aaggaatcat gagaagtcag ccgagaccat agtagtgaag aaacttctgt
    38761 aatggaagtg gagtgaagtg aggaatcatc aaacggtagg ggataggctg tttgaagggt
    38821 gctacgaaaa agatagggta aggtgaaatt atagcggaat gaaataagat atgaacaaat
    38881 tgattaggga aatcaaatga atttatagaa atcttttagc agtcatggcg tcctattcta
    38941 gtttcaaaat gctataaata cgaacaaatt gattgggaaa ttcaaatcgc tttctatcaa
    39001 tgttttagaa gatacagtgc cctagtccaa cttcaatata ctataaaaga acagatggaa
    39061 gcaattatga tttacttcta tctttaaaat aaatgatctg ataggaaaaa tgtgtcccct
    39121 cataaaaaat aggatagtac ggatggaagg cttttgtaga ctggaggacg aaggaattta
    39181 gaaactctcg ttaaaagtta gttgagccgg agtatggtgg tgtgaataat tatcaaaaat
    39241 tatttccaaa tcgaaatagt tgacagttag aacgatgagt gttacaatta ttttattcat
    39301 ttcgatatcg aaataaattg gaggtgttat gaaagatagt catttgctag cccatcatat
    39361 tcgtttgttg aatgggcgga tttttcaaaa gttactgagt caagatcctg aggctcttta
    39421 taggggtgaa cagggcaaga ttttagcggt tttatggaat agtgaaactg gctgcgcaac
    39481 tgcgacagat atcgcgcttg cgactgggct tgcgaataat acgctgacga ctatgataaa
    39541 aaagctagag gaacaaaagc ttgtaattgt tagtccgtgt ggaaaagaca agcgtaagaa
    39601 gtatttagtt ttaacggagt taggcaagtt ccagaaagaa gtggggcatc gtgtcagtca
    39661 gaaattggat actatctttt acaaaggatt ttcagaggaa gaaattcacc aatttgaagg
    39721 ttttcaagaa agaattttgg caaatctgaa agagaaggaa aatgaggttt agaatatgtc
    39781 acaacaagtg aaaaatgctc acaacctata catccatgcc attcaagacg gacgagttgc
    39841 tgaggctcaa gcccagtctg taggggatac ctatatccaa cattcgacag gtgttcctga
    39901 cgggaaagaa ggatttgcag ccttctttgc agatttcttt gagcgtcatc cagagcgtca
    39961 gattaagatt gtccgcacca ttgaggatgg caatctggtc tttgttcatg ttcatcaata
    40021 tctgaatggt ggagaagctc aatgggtgac gacggatact ttccgtgcgg atgagaatgg
    40081 tcgtattgtt gagcattggg atgtcattga ctactatcga acacctgaaa atgaccaact
    40141 agatcaaatt tttggagatt ttgaaatcaa ggatttggac aagaaagcag aaaataaaaa
    40201 gctggttcgc cgtttcttga cagaaacttt ccaaaatggg gagctagagc agtggagtga
    40261 ttatgtggca gacgatttga ttcagcataa tcatgagatt ggacaaggaa gtgctgctta
    40321 taaaaactat gtggctgaat atagtgtcac ttttgacttt gttttccaac tcttaggaca
    40381 aggaaactat gtggttagct atggtcagac tcagattgat ggcgttgctt atgcccagta
    40441 cgatatcttc cgtttagaga acgggaaaat tgtggagcat tgggataata aggaagtcat
    40501 gcctaaggta gaagacttga ctaatcgagg gaagttttaa attgaggaca aagaatgatt
    40561 gaatacaaaa atgtagcact gcgctacaca gaaaaggatg tcttgagaga tgtcaactta
    40621 cagattgagg atggggaatt tatggtttta gtagggcctt ctgggtcagg taagacgacc
    40681 atgctcaaga tgattaaccg tcttttggaa ccaactgatg gaaatattta tatggatggg
    40741 aagcgcatca aagactatga tgagcgtgaa cttcgtcttt ctactggtta tgttttacag
    40801 gctattgctc tttttccaaa tctaacagtt gcggaaaata ttgctctcat tcctgaaatg
    40861 aaggggtgga gcaaggaaga aattacgaag aaaacagaag agcttttggc taaggttggt
    40921 ttaccagtag ccgagtatgg gcatcgctta cctagtgaat tatctggtgg agaacagcaa
    40981 cgggtcggta ttgtccgagc tatgattggt cagcccaaga ttttcctcat ggatgaaccc
    41041 ttttcggcct tggatgctat ttcgagaaaa cagttgcagg ttctgacaaa agaattgcat
    41101 aaagagtttg ggatgacaac gatttttgta acccatgata cggatgaagc cttgaagttg
    41161 gcggaccgta ttgctgtctt gcaggatgga gaaattcgcc aggtagcgaa tcccgagaca
    41221 attttaaaag tgcctgcaac agactttgta gcagacttgt ttggaggtag tgttcatgac
    41281 taatttaatt gcaacttttc aggatcgttt tagtgattgg ttgacagctc tatctcaaca
    41341 tttgcagttg tcacttttga ccttgttact agctattttg cttgcgattc ccttggctgt
    41401 ttttcttcgc tatcatgaga agctggccga ctgggtcttg cagattgcag gtattttcca
    41461 gaccatcccg tctctggcct tgttggggct ctttatccct ttgatgggaa ttgggacctt
    41521 gccggctttg acagctctag tgatttatgc gatttttccg attttacaaa atactattac
    41581 tgggctgaag ggaattgatc cgagtcttca agaggctggg attgcctttg ggatgaccag
    41641 atgggagcgt ctcaagaagt ttgaaattcc acttgccatg cctgttatca tgtctggaat
    41701 tcggacggca gcggtcttga ttatcggtac ggctaccttg gcgaccttga ttggggcagg
    41761 gggactgggt tcctttatcc tgttgggaat tgaccgtaat aatgccagtt tgattttgat
    41821 tggggccctt tcttctgcag tgctagctat tgcctttaac ttcctactaa aagtaatgga
    41881 aaaagcgaaa ttgcggacga ttttctctgg ttttgccttg gtggctttat tactgggtct
    41941 gtcttatagt ccagctcttt tggctcaaaa agagaaggaa aacttgatta ttgctgggaa
    42001 aataggccca gaaccagaaa ttttggctaa tatgtataag ttgctgattg aagaaaatac
    42061 cagcatgact gcgactgtta aaccgaattt tgggacgaca agtttccttt atgaagctct
    42121 gaaaaaaggt gatattgaca tttatcctga atttaccggt acggtgactg aaagtttgct
    42181 tcaaccatca cccaaggtga gtcatgagcc agagcaggtt tatcaagtgg cgcgtgatgg
    42241 cattgccaag caggatcatc tagcctatct caaacctatg tcttatcaaa atacctatgc
    42301 tgtagctgtt ccgaaaaaga ttgctcaaga atatggcttg aagaccattt cggatttgaa
    42361 aaaagtggaa gggcagctga aggcaggctt tacgcttgag tttaacgacc gtgaagatgg
    42421 aaataagggc ttgcaatcaa tgtatggtct caatctcaat gtggcgacta tgcagccagc
    42481 tcttcgttat caggcaattc agtcagggga tattcaaatc acggatgcct attcgactga
    42541 tgcggaattg gagcgttatg atttacaggt cttggaagat gacaagcaac tcttcccacc
    42601 ttatcaaggg gctccactca tgaaagaagc tcttctcaag aaacacccag agttggaaag
    42661 agttcttaat acattggctg gtaagattac agaaagccag atgagccagc tcaactacca
    42721 agtcggtgtt gaaggcaagt cagcaaagca agtagccaag gagtttctcc aagaacaagg
    42781 tttgttgaag aaatgatggg acagagactt taaacatact gaactcaact tccttaaacg
    42841 actagataaa agaatgctca gacaatttcg tctgggcttt tttgatgtga gaatgactga
    42901 atgtcactta aaatggaaag aaagagaaaa ttttcatgat tttctaaaat tttactgtaa
    42961 agacagttga ctattcataa aataggtgta taatattttg tgaactactt aacaaataag
    43021 aggttttagc tcatgtcgac taaggttaga aatcttgtgt ataggcagtt cattatctaa
    43081 tagagcgttg cgtccgaaag tctatccaga cacggctctt taaaaacaaa aggagaaatg
    43141 atgcatactt atttgcaaaa gaaaattgaa aatatcaaaa caaccctagg tgaaatgtca
    43201 ggtggttacc gtcgtatggt tgcggctatg gctgatttag gattttcagg aactatgaag
    43261 gctatctggg atgacctctt tgcccatcgt agttttgccc agtggattta tttgctggtt
    43321 ttaggaagtt ttcctctctg gctggagttg gtttacgaac atcgtattgt tgactggatt
    43381 gggatgattt gtagcttgac agggattatc tgtgtaatct ttgtatcgga aggtcgagca
    43441 agtaattatc tttttggctt gattaactct gttatttacc ttattttggc cctacagaaa
    43501 ggcttttatg gtgaggtgct gacgacactt tacttcacag tcatgcagcc aattggactt
    43561 ctagtttgga tttatcaggc acagtttaag aaggaaaagc aggagtttgt cgcgcgtaaa
    43621 ctggacggca agggctggac aaagtatctt tccattagtg tgctttggtg gttggccttt
    43681 ggcttcattt atcagtctat tggtgccaat cgtccctatc gtgattcaat cacagatgca
    43741 accaatgggg tagggcaaat cctcatgaca gctgtttacc gtgaacagtg gatattctgg
    43801 gcggctacca atgttttttc aatctatctc tggtggggag aaagcctgca aattcaaggg
    43861 aaatatctaa tttatctcat taacagtcta gttggttggt atcaatggag caaggcagct
    43921 aagcagaata ctgatttact taactaggaa aagatgtttg aaagtgctgt tttgagattt
    43981 cgattaaaac agatatagtt gataatcaag gatttatagt atgaaaaaga ggatcggcgg
    44041 gtcctctttt gttgttgaaa agataaaaaa ctcagtaacc tagaaataag acaactgagc
    44101 tttactctat attcaatttt taggaatgag aaggtctaga taaaattgga caacttcctg
    44161 gcctgtgaaa tcttgacctt ttttgagcca ccaggtcaat gtctcgataa agttggacac
    44221 gaccaagtgt tggaggtaag aagtaggcat attagggtgg gcttctttta aattatcagc
    44281 tagcacggaa tagacatggt gttctagctc tttatggagt tgacggagga agtagtcatt
    44341 tttggaaaat agcagactgg tgatatggtc ttggttttta tgaaaatgga gaaagaggtg
    44401 ggcgaggtag tcctcggttg aaatggcttg ctctctttca aaaagatgat ggaagaggta
    44461 gcggcagagc tggtccagaa gaagctcctt actttcatag tgacagtaaa aggtggatct
    44521 tcccacatct gcgagatcaa tgatatcctg aacagtagtg gcctcgtagc ccttagcatt
    44581 caaaagttgt ataaaagctt gatagatggc ttttttggtt ttgctgatac ggcggtcaat
    44641 gttagtcata tggacactta aggcaaattg ttcagaactg aataaagctg acgttttgct
    44701 tctatccttt ctttgagttt tagtggataa tgataatgaa caaggtgttc ataaatctat
    44761 tataacaaag gaatgagaaa tatgaaggca aaatatgctg tttgggtggc ttttttctta
    44821 aatttgactt atgccattgt tgagtttatt gcaggtggag tatttggttc tagcgctgtt
    44881 cttgctgact ctgtgcatga cttgggagat gcgattgcaa ttggaatatc agcttttcta
    44941 gaaacaatct ccaatcgtga agaagacaat cagtacacct tgggctataa gcggtttagc
    45001 ctgctaggag ccttggtaac agctgtgatt ctcgtaacgg gctctgttct agtcattttg
    45061 gaaaatgtca cgaagatttt gcatccgcaa ccagtcaatg atgaggggat tctctggtta
    45121 ggaattattg cgattactat caatctgtta gcgagtctgg tggttggtaa gggaaagaca
    45181 aagaatgagt ctattctgag tttgcatttt ctggaagata cgctagggtg ggtagctgtt
    45241 atcctgatgg cgattgttct tcgatttacg gactggtata tcctagatcc tcttttgtcc
    45301 cttgtcattt ctttctttat tctttcaaaa gcccttccac gtttttggtc tacactcaag
    45361 attttcttgg atgctgtgcc agaaggtctt gatatcaagc aagtaaagag tggcctggag
    45421 cgattggaca atgtggccag ccttaatcag cttaatctct ggactatgga tgctttggaa
    45481 aaaaatgcca ttgtacatgt ttgtctaaaa gaaatggaac atatggaaac ttgtaaagag
    45541 tctattcgaa ttttcctaaa agattgtggt tttcaaaata ttaccattga aattgatgct
    45601 gacctagaaa ctcaccaaac ccataagcga aaggtgtgtg acttggaacg gagttatgag
    45661 catcaacatt agaaaaaagt gaaaaatact tgggtactat cttatttgga atagagtaat
    45721 ttctttatta tttaaatatt tcaaaaattg gtaagagaag agcattgtat aaactccaga
    45781 tatatgattg ttaatgataa aaatttttcg attagataca aaatgcttga cttggagtca
    45841 actcaaagtt atataataag ataagtgagt tagaatagcg tgaattcagt gaatgaaatg
    45901 agaggaggtt agcgtgtgaa tattaaatct gccagtgatt tgttgggaat ttcagcggat
    45961 acgattcggt attatgaacg ggttggtctt gtgccaccga ttactcgtac tgctactggg
    46021 attcgtgatt ttcaagatca ggatatcgaa gcgctggaat ttattaagtg ttttcgttcg
    46081 gcgggtgtct ctgtagatag tttagttgac tatatgtcgc tctaccaaaa gggagatgaa
    46141 acgagagagg agaggcttgg tattttagaa gaggaaaagc aaaaattaga ggagcgcttg
    46201 tctcagctac agacagcttt aaatcgttta aatctcaaaa ttaaacttta taaggaagga
    46261 aaattttaaa tgaaatcagc agtatataca aaggcaggtc aggttggact tgctagcatt
    46321 gaacgtccgc aaataataga agcggatgat gtgattattc gtgtggttcg tgcgtgcgtt
    46381 tgtggttcag atttatggag gtaccgtaat ccagaaacga aagctggaca taaaaatagt
    46441 ggacacgaag cgattgggat tgttgaagaa gctggggaag ccattacgac ggtgaaacca
    46501 ggtgattttg tgattgtccc ttttacacat ggatgtggtg agtgtgatgc ctgtcttgct
    46561 ggatttgacg gttcttgcga caatcatatt ggtaataatt tggggggtga ttttcaggca
    46621 gaatatattc gcttccacta tgcaaactgg gcgctggtta aaatccctgg tcaaccttct
    46681 gattatacag aagggatgct caagtccctt ttgactcttg cagatgtcat gccgacaggc
    46741 tatcatgcag cgcgtgttgc aaatgttcaa aaaggggaca aggttgttgt tatcggtgat
    46801 ggggctgttg gtcaatgtgc tgtcatcgcg gctaagatgc gtggagcatc acaaattatc
    46861 cttatgagcc gtcatgaaga ccgtcaaaag atggctatgg agtcaggtgc gacagctgtt
    46921 gttgcagaac gtggtcaaga aggaattacc aaggtgcgtg aaatcctcgg cggaggagca
    46981 gacgcagcac ttgaatgtgt tggtacggag gctgctatag aacaggcgct aggtgttctt
    47041 cataatggag ggcgtatggg ctttgtagga gtcccacact ataataatcg tgctcttggt
    47101 tcgacattta tgcaaaatat ctctgtagca ggtggggcag cttctgctac aacatacgat
    47161 aagcaatttt tactaaaagc cgtccttgat ggtgatatca atccaggtcg cgtctttact
    47221 tcaagttata aactggaaga tatcgaccaa gcctataaag atatggatga acgtaagaca
    47281 attaagtcta tgattgtaat cgaataaaaa acgaatagga gttttagaac tctattcgtt
    47341 ttttatgtta tcctattctt gatttagggt actttctctt aatgtcagtc tggttcccag
    47401 catggtcagg ctaggaattt tgcgaccgtg gaggacttcc ttgttaagaa tatccatacc
    47461 tgctcgcccc atttcttcag tataaactgt aatactagag aggggaggat agacctgttt
    47521 ggtcagactg gtgtcgttga atgaaatgag gctgacgcga tctggcaggc tgattccagc
    47581 ttcttggagg gcacggaggg caccgatagc taaactatcg ctggctgcga aaaatgctgg
    47641 cggaagttgg tctcccaagc tctgaatggc ctccttcatt aagtcatagc cagactgggc
    47701 agtaaatctt ccttgaaaga ccagttcatc atgatagatt cccctcgctt gactgtagtt
    47761 tttgaagttt tctagacgct tgtcctgaat gatttcttct tggtctgttg tttcctcaag
    47821 ccctgttaga atcccgatgc ggtccatccc ttgactgagg aaataatcga caacctgttt
    47881 catagcagtg taaaaatccg tgataataca ggtatgtccc agggaaagtg tatcgctgtc
    47941 tagaaataca agaggctttt ggtattcttc aaaggcagaa atctgagctc ggctaaattt
    48001 tccgatgcag agaatcccaa tcacttcctc gcttagggta aaaggatggt cattaaaata
    48061 gcgcaagata tcgtagtcca actcttgggc tcttttttct attcctaggc gaatctggta
    48121 gtagtagagg tcgtctagct ccccttgttc gctgacccat tgaataatgg caatcttttg
    48181 cttgggttta tgggactcgc ctgtcttgag gtgcttggtg tagcccagct cttcagcaac
    48241 ggttaaaata cggtgtctgg tttcttctgt aacagatagg ctctggtcgc ggttgaggac
    48301 acgggatacg gtcgcgatag agacagaggc tagctgtgca atgtctttta aggtagccat
    48361 aaatcctcct tgattaggtt agtatatcat atttttcttc tttttactga tgttttacta
    48421 aaattttagt aaaaaggatt gaccttggga aattccttgg atacaataga agaaaacgat
    48481 tacacgttaa gatggcttaa cggacagtca aaggagaatt catatggcac aacatcttac
    48541 tactgaagtc cttcgcaaag actttcttgc tgtttttggt caagaagcag accaaacctt
    48601 cttttcacca ggtcgtatta atttgattgg tgaacacaca gactacaacg gtgggcacgt
    48661 ttttcctgct gctatttcct tgggaactta cggtgcagct cgtaagcgtg acgaccaagt
    48721 cttgcgtttc tactcagcta actttgagga caagggcatt atcgaagtgc ctctcgctga
    48781 cctcaagttt gaaaaagagc acaactggac caattatcca aaaggggttc ttcatttctt
    48841 gcaagaagct gggcacgtga ttgacaaagg ttttgatttt tatgtttatg ggaatatccc
    48901 aaatggtgct ggcttgtctt cttcagcatc cttggagctc ttgacaggag tcgtggcaga
    48961 gcatctcttt gatttaaaat tagagcgtct cgatttggtt aaaatcggca aacaaacaga
    49021 aaacaacttt atcggagtca actctggtat catggaccag tttgctattg gtatgggggc
    49081 tgatcaacgt gctatttacc ttgataccaa caccttagag tatgatttgg tgccacttga
    49141 tttgaaggac aatgtcgttg ttatcatgaa caccaacaaa cgccgtgaat tggcggactc
    49201 taaatacaat gaacgtcgtg ctgagtgtga aaaagcagtg gaagaattgc aagttgcctt
    49261 ggatattcag accctgggtg aattggacga gtgggccgtt gaccaatata gctatctaat
    49321 taaagatgaa aatcgtttga aacgtgctcg ccatgctgtg cttgaaaacc aacgtaccct
    49381 taaagctcaa gcagcccttc aagcaggtga tttggaaaca tttggtcgtt tgatgaatgc
    49441 gtcacacgtt tctctggagc atgattatga agtaactggt ttggaattag atacccttgt
    49501 tcacacagct tgggcacaag aaggagttct cggtgctcgt atgacagggg ctggttttgg
    49561 tggctgtgcc attgccttgg ttcaaaaaga tactgttgag gcctttaagg aagctgtagg
    49621 caaacactac gaggaagtag ttggatacgc tccaagcttc tatatcgctg aagttgcagg
    49681 tggcactcgc gtccttgact agtcaaaagg aggctctata gtgaccttag tagataaatt
    49741 tgtaacacat gtcatttctg aaagttcatt tgaggaaatg gatcgaatct acctgaccaa
    49801 tcgtgttttg gcacgagtgg gagaaggtgt tttggaagtt gagaccaatc tggataaatt
    49861 gattgacctc aaggcccagc tagttgagga agccgttcga ttagagacga ttgaggatag
    49921 tcagactgcg cgtgaaatcc ttggtactga actgatggac ttggtgactc cttgtccgag
    49981 tcaggtcaat cgtgacttct gggaagccta tgcctactct cctgagcaag cgatagagga
    50041 tttttatcaa ctcagtcaga aaaatgacta catcaaactc aaggccattg ctaaaaatat
    50101 cgcttatcgt gttccatctg attatggaga acttgaaatt accatcaatc tctctaagcc
    50161 tgaaaaggat ccgaaagaga ttgcggtagc caagttggtg caagctagta attatcctca
    50221 gtgtcaactt tgtttagaga atgagggtta ccatggtcgg gtcaaccacc cagctcgcag
    50281 caaccaccgg attatccgtt ttgaaatggt tggtcaggaa tgggggttcc agtattcgcc
    50341 ctatgcttac tttaatgagc attgtatctt tttagatggc cagcatcgtc ccatggccat
    50401 tagtcgtcag agttttgaac gtctgttggc tatcgtagag cagtttccag gatattttgc
    50461 tggatctaat gccgacctgc cgattgtggg gggctctatt ctaactcacg atcattatca
    50521 gggaggccgt cacgtatttc ctatggaatt ggctcccttg caaaagacct tccgatttgc
    50581 tggttttgag caggtcaagg ctggaattat caagtggcca atgtctgtcc tacgcttgac
    50641 ttcggattcc aaagaggatt tgattaactt agctgataag attttccagg aatggcgtca
    50701 gtattcagat tctagtgtgc agattttagc agagacagac gggacgccgc atcacaccat
    50761 cacaccaata gcgcgtaagc gtgatggaca gtttgagttg gacttggtct tgcgagacaa
    50821 tcagacttca gcagagcatc ctgatggcat ctatcatccc cacaaggatg tccaacatat
    50881 caagaaggaa aatatcggct tgattgaggt catgggcttg gcaatcttgc caccacgtct
    50941 gaaagaagaa gtggagcaag tcgctagcta tcttgtagga gaagctgtta cagttgccga
    51001 ttatcatcag gagtgggcag accaactcaa atcccaacat ccagacctaa cggataaaga
    51061 aaaagccctt gcaatcgtca aggactctgt gggtgctatc tttgtgcgtg tacttgagga
    51121 tgcaggagtc tacaagcaga cagaacaagg gcagacagcc tttatgcgct ttgtggaaca
    51181 ggtcggaatt tcactagact aggagctttc tccttgcaca gtcctataaa aagtagtatc
    51241 atagtgtcgt ttgaaatatc aggaggaaac gatgaaagac tttcattttg acgctatatc
    51301 tgcctttgaa aattacgaaa ttgaaaaaat gagagatggt cacgttgtgg tgacgaccaa
    51361 agtagtgaac tcgtcgctca actactatgg caatgcccat ggtggctatc tattcacgct
    51421 atgtgaccaa atcagtggtt tggtggttat ctcgctggga cttgatgggg tgacactcca
    51481 atcctctatc aactacctta aggcaggaaa actcgacgat gtattgacca ttaaaggaga
    51541 atgtgtccat caaggtcgta caacctgtgt gatggatgtg gatatcacca atcaagaggg
    51601 cagaaatgtc tgtaaagcaa cctttaccat gtttgtcaca ggccaaaggt ctgaggaaag
    51661 acgggtaagg atataaagaa aggtgagtgg gataaattta tctcactcat ttttaattta
    51721 tgagatatgt tagaaggaaa tataaaagag agtggtgaaa tacaaatgta ataggtacat
    51781 atatgtggta tactagttat agtagatttt aattgcttat atcgagtgag ttctcatatt
    51841 agtgaggaat ttttaaatgg aattacactt taatttagaa ttagtagaaa cctataaaag
    51901 taatagccaa aaggcacgta tcttaacgga ggattgggtt tatcgtcagt cttattgccc
    51961 taattgtggg aacaatccct taaatcattt tgaaaataat cggcctgtag cagattttta
    52021 ctgtaatcat tgtagtgagg agtttgaact aaagagcaaa aaaggaaatt tttcatcaac
    52081 aatcaatgat ggtgcttatg caacgatgat gaagcgtgtg caggcagata ataatcctaa
    52141 tttctttttt ttaacttaca caaaaaattt tgaggtaaat aactttcttg tccttccgaa
    52201 gcaatttgtt acaccgaaat caattattca aagaaaacca cttgcaccaa ctgctagacg
    52261 agcaggttgg attggttgta acattgattt atcacaagta ccttctaaag gaaggatatt
    52321 tcttgtgcaa gatggacaag ttagagatcc agaaaaagtt acaaaagaat ttaagcaagg
    52381 tttattttta aggaagagct ctctgtcatc aagaggttgg acaatagaaa ttctaaattg
    52441 tatagataag atagagggtt cagaatttac ccttgaagat atgtatcgtt ttgaaagtga
    52501 cctaaaaaat atctttgtta agaacaatca tatcaaagaa aagattaggc aacagcttca
    52561 aatattaaga gacaaagaaa taatagaatt taaaggtaga ggaaagtatc ggaaattatg
    52621 aaaacgaaac aacttgttgc atcagaagag gtgtatgatt tcttaaaagt catctggcct
    52681 gattatgaaa ctgaaagccg ttacgataac ctaagtttaa tcgtctgtac cttatcagat
    52741 cccgattgtg tgagatggtt atctgaaaat atgaaatttg gtgacgaaaa acaactagct
    52801 ttgatgaagg aaaaatatgg gtgggaagta ggagataaat tgccagagtg gctacatagc
    52861 tcctatcata gattattgtt aataggtgaa ttattggaaa gcaatctaaa actgaaaaag
    52921 tatacagtag aaattacaga aactttatca cgtttagtaa gtatagaggc tgaaaatcca
    52981 gatgaagccg aacgacttgt aagagaaaag tataagagtt gtgaaattgt tcttgatgca
    53041 gatgattttc aggactatga cactagcata tatgaatagg tagatgtttt tattttgtca
    53101 cacaaaaaag aggctcgcac ctctttttct tatttctttt tatgatttaa tacggcattg
    53161 aggacaatag cgagtaggct ggctacgaag attccgtttg agaagaacat ttggaaggct
    53221 gtcggcatgc tgacaaagag attactgttg ttgagaccga cacctgcagc gattgaaaca
    53281 gctgcgataa ggaagttgtg ttcattgtta gcaaagtcaa ctcgggctag gatttgcatc
    53341 ccttgaatag atacaaaacc aaacatcacc agcatggcac cgccgaggac ggagcttgga
    53401 atgatttggg caagggcacc aaacttagga agcagtccaa ggagaaccag gaaaccagct
    53461 gcgtagtaga ttggcaggcg ttttttgatg cctgacaatt taaccaaacc aacgttttgt
    53521 gaaaatccgg tgtaagggaa ggtgttaaag attcctccga gaagtacggc caaaccttct
    53581 gcgcggtaac cgttgcgaag gcgcgtgctg tcgattggat cttttgtgat atcagacaag
    53641 gctagataaa caccagttga ctcaaccata gacaccgttg cgatgataca catcatgaca
    53701 atagatgaga tttcaaaggt tggcatccca aagtagagtg gagttgggac atggacaagt
    53761 ggagctaccg caacaggaga gaagtccacc aagcccatag tagcagcaat ggcagttcca
    53821 acaaccagac caatcaaaat agagatagac ttgataaatc ctttggtaaa gatgttgatc
    53881 aagaggataa tcagaacagt aatagctgaa agcaagagac tttgaccagt tggctctgga
    53941 acgttatttc ccatatttcc aatagcgaca gggatcaagg ttaaaccaat cgtggtaata
    54001 acagatcctg ttacgataga tgggaaaaga ttggctactt ttgagaagat gcctgaaaca
    54061 agaaccacgt aaatcccaga tgcgataagg gcaccaaaca tagcgccact accatggctt
    54121 tgcccaatca taatcaaggg agcgaccgac tggaatgcaa ctccaagaac gactgggagt
    54181 ccaatcccaa agtatttgtt gagttggagt tggaggaagg ttgccacccc acacatgaag
    54241 atatctgtag aaatcaggta ggtcaactgc tcagctgaat agccaagggc tgtcgcaatc
    54301 atgatgggaa ccaggataga tcctgagtac atggctagta agtgctgcaa gcccagaacg
    54361 gctgcttgcg agtgtttttc ttgagtttgc attagagatc tgcctcctta aataagacct
    54421 gaccattttc aaaacgatcc aagcgagcaa gtgataggac agggtagcct gctttttcaa
    54481 gcaaatcacg accatcttgg aaggatttct caatcacgat accgatagct tggactgtgg
    54541 caccggcctg ttcgatgatt tgaatcaagc ctttagcagc ttggccatta gcaaggaaat
    54601 cgtcgataat caaaaccttg tcctctggtg agaggaattt tccagcgata gaaacagtgc
    54661 tggtcacctg cttggtaaag gagtagactt gagcagttaa gatgccttcg ttcatggtga
    54721 tgttcttagc ttttttggcg aaaatcatgg gaacgtttaa ggcttcagct gtaaaaacgg
    54781 ctggggcaat acccgacgct tcaatggtta cgaccttggt aatgccggca gcagcaaatt
    54841 tttccgcaaa aaccttacca atctctcgca tcaagctaaa gtcaacttgg tgggttaaaa
    54901 aggaatctac cttgaggatg ttatcatcca agatatgccc atccttgagg atgcgctctt
    54961 ctaataattt cataagacct cctaaagtct aaaagttaat ttacttgttg tttaaatatt
    55021 tctatagtga tcccttttgc taatactata tatttgataa aactattacg agcgaagcga
    55081 gtcttatcaa atatttcccg ttgtagtggt atcatagaca ataatcttgt tattgtctat
    55141 gacgggattt ttgagagtaa aatagttcgg ggaactattt tagcctaagc ctagaaatga
    55201 aagagctagg ggctcaaaaa ttagggatga aattccctgg attcctgaaa ttattcacag
    55261 gataatttca cctcccgtcc gcactaatta agggaaatat taaaaatatt caaaaaagac
    55321 ctacttaatc tctaagtaag tcccctaaat agacatggca aaaacggcca tatctcactg
    55381 ctgacttact tattgttagg tgttccggca ccttgtagaa acgtcgtgcc aattcacgac
    55441 ataaacaagt aaaacgatat tcaattttaa ataggcttga gccaatgttt ttattttaca
    55501 ctaaataact ttataaatca actattttgt tagtgtttcg gtttaaaaag cgaacaaaaa
    55561 gaagagaggg tgaacaaaaa ctccattgta agctaacatt tatactaaat gaaaatcaaa
    55621 gagcaaacta ggaagctatc cacaacctca aaacactgtt ttgaggttgt ggatagaatt
    55681 gacagagtca gtatcatata cctacggtaa ggcgacgttg acgtggcttg aagagatttt
    55741 cgaagagtat tagaagattt ttccatcata aaaggcatac tatcaagttt ttagacacct
    55801 gacaatatgc ctttttctaa ctttaaagac ttttcccaat ttttattatt ctactcgcta
    55861 aatcttaaaa aatagccatc tggatccaaa actgcaaatt tatgaggata gatataggga
    55921 tcactgacac gaaactttct tttggtcaag agacgataaa taggatagtt tgcctccatc
    55981 actttttgat agagttttgg aacatccttt atgccaaagg agagattgac tccacgacca
    56041 aaggggtagg tcagttcagc tagttgatcc tttgttccct cctctaacat tagttgacac
    56101 tcttcaagag aaagagaaag ttttcttctg gacgttagta ttcaatccta aaacccagta
    56161 aaccacagta gaaggaccgg gactgttcga tattcgatac aagaaactcg ggaatgaccg
    56221 cattgtagtc catatagaaa atccttacaa gtcaatttcc aagacaatcg gtgtatggtc
    56281 ttggcgagca cctgagtcaa tcatatcaga tttagtgacc ttgtcagcga tacggttact
    56341 tgtgagccag tagtcgattc tccagcctgt attgttgatt ttagaagttt tgctgcgttg
    56401 tgcccaccaa gtgtagcgtt caggaacatc gccatgaaca tggcggaagg tgtctgtaaa
    56461 tccagttgcc aaaaggttgg taaatccagc acgttcctcg tcagtaaatc caggtgaacg
    56521 gcggttgcta gcaggatttg caaggtcgat ttcattgtgg gctacgttgt agtcaccggt
    56581 cgcaaggact ggtttttctt tgtctagttc agccaaatac tccgcatatt tgacatccca
    56641 gacttggcgt tcttccaagc gtttgagacc gtcaccagcg tttggagtgt aaacttgggt
    56701 tacgaaaaat gcatcaaatt ctagagtgat gatacggcct tccaagtcca tggtagaagg
    56761 ggcaccgatt tctggaaaac tgatcgtagg cgtaagttct ttcttataaa ggaacatggt
    56821 tccagcatag cctttacggg caggctcttg ggaagagcgc catgtgtttt cgtagcctgg
    56881 gaagagttct tctaaaattt ccacgtgttt ctttgtaggt cctttggcag aaagcttggt
    56941 ttcttggata gcaatgatat cagcattttc agcgaccaag gtttgtagga cttcttggga
    57001 caatttggca cgagctgagt cactagttag ggcagcgttt agggaatcaa tattccatga
    57061 gataagtttc ataaagttac ctttttcatt cagattatag attttattat accaaaaaaa
    57121 gatctatttc cccaacgtat ggtttgaaaa attactctct ttcgtttata attaagaatg
    57181 attttatgaa agggagtgaa aatacatgaa attctactct tatgactatg tactcagcca
    57241 aatcggtcag caaaatggta tcatggttgg ctttgggatt gttttattag ctgtgacagt
    57301 tttttttgct ttcaaggcat accatgataa aaaaggaacc aaatttcgtg agttggtcat
    57361 aatttcagct ctggccttat ttagctatgc ttttggtcag catcacgact tatcaaaaca
    57421 atcaagtttc taacaataaa tttcaaactt cacttcattt catcgaggtt gtttccaaag
    57481 atttgggagt agacaagtca gaagtctatg ttaatacttc cacaaacaca gatggcgcac
    57541 ttatcaaggt gggagatcgc tattatcgtg ccctaaacgg aagtgagcca gacaagtacc
    57601 tgttagagaa agtcgaattg tataagacag acgcaattga actggtggat gtgaacaaat
    57661 gacacttaat tatatcgaaa ttttaatcaa actgatcttg actctcaaat agctcaacaa
    57721 caatgttcac tttgtgaaac gtttgattga tggtaagcca actctcctta tcaaaaatgg
    57781 gaatattgac ccagaagcct gtcgttcagt tggtttgtct gcatcggatg tatccctcaa
    57841 acttcgtagc caagggattt tccagatgaa gcaagtcaaa cgagctgtgc aagagcaaaa
    57901 tgggcaactc atcgttgtgc aaatgggaga tgaaaatcct aagtatccag ttgtgactga
    57961 cggtgtgatt caagtagatg tcttggaatc gattggtcgt agcgaagagt ggttgcttga
    58021 taacctcagt aaacaagggc atgacaatgt agccaatatc tttattgctg aatatgacaa
    58081 gggtgctgtt acagtcgtaa cttatgaata agaaaaacct ggggtcttgt actcttcgaa
    58141 aatctcttca aaccgcgtca acgtcgcctt gccgtatgta ggttactgac ttcgtcagtt
    58201 ctatctacaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct agtttgctct
    58261 ttgattttca ttgagtattg gcctcaggtt tccatttgca atcagaaagg gattttatgt
    58321 ccattattca aaaactttgg tggtttttca agttagaaaa acgccgttat ctagtcggaa
    58381 ttgtggccct gatcttggtt tccgtcctca atctcattcc tcctatggtt atggggcggg
    58441 tcattgatgc catcacatcg gggcaattaa cccagcagga cctccttctt agcctatttt
    58501 acttgctact tgcagccttt ggtatgtact atttgcgcta tgtgtggcgt atgtatatcc
    58561 ttgggacctc ttattgcttg ggacagatca tgcggtctcg cttgtttaag catttcacaa
    58621 aaatgtcgtc agtcttttat caaacctatc ggacgggtga tctgatggca cacgcaacca
    58681 atgatatcaa tgccttgact cgtttagcag gtggcggtgt catgtctgcg gtggatgcct
    58741 ctatcacggc tctggtgact ttgttgacca tgctctttag catctcatgg cagatgactc
    58801 ttgttgccat tctcccccta cctttcatgg cctatgcgac tagtcgccta gggagaaaga
    58861 ctcataaggc ctttggcgaa tcccaagctg ctttttctga actcaataac aaggtacagg
    58921 agtccgtatc aggtatcaaa gtgaccaagt ctttcggtta tcaggcagac gagttgaagt
    58981 cttttcaggc agtcaatgaa ttaaccttcc aaaagaacct gcaaaccatg aaatatgata
    59041 gtctctttga ccctatggtt ctcttgtttg ttggttcgtc ctatgtttta acgcttttgg
    59101 ttggctcctt gatggttcag gaagggcaga ttacagttgg gaatctggtc acctttatca
    59161 gctatttgga tatgctggtc tggcctctta tggccatcgg cttcctcttt aatactactc
    59221 agcgagggaa ggtttcttac cagcggattg aaaatctttt gtctcaggaa tctcctgtac
    59281 aagaccctga gtttcctctg gatggtattg aaaatgggcg tttggagtat gccattgaca
    59341 gctttgcttt tgaaaatgag gaaacactga cggatattca ctttagtttg gcaaaagggc
    59401 aaacactggg cttggttggg cagacaggct ctgggaaaac gtccttaatc aagcttctct
    59461 tgcgtgaata cgatgtggat aagggcgcca tttatctaaa cggtcacgat attcgggact
    59521 atcgtctgac agaccttcgc agtctcatgg gctatgttcc tcaggaccag tttctctttg
    59581 caacttcaat cctagacaat atccgctttg gcaatcctaa cttgcccctt tcagcggtcg
    59641 aggaagctac taagctagcc cgagtttacc aagatattgt agacatgcct caaggatttg
    59701 atacgctgat tggtgaaaaa ggagtcagtc tttctggtgg tcaaaagcaa cggttggcta
    59761 tgagtcgggc tatgatttta aaccctgata tcttgatttt ggatgattcc ttatccgccg
    59821 tagatgccaa gacagagtat gcgattatcg acaacctcaa ggagacgcga aaggacaaga
    59881 caaccattat cactgcccat cgcctcagtg ctgttgtcca tgcagatttt attttagttc
    59941 tacaaaatgg tcaaattatc gaacgaggca ggcacgaaga cttgctagcg atggatggct
    60001 ggtatgccca aacctaccag tctcagcagt tagaaatgaa aggagaagaa gatgcagaat
    60061 aaacaagaac aatgggctgt attgaagcgc ttgatgtctt atctcaagtc ttatggactc
    60121 ctgatctttt tggcactcag ttttctccta gcgacgacgg tcattaaaag tgtcataccc
    60181 ctcgtggctt cccactttat cgaccagtat ctcagcaatc ttaaccaact agccgttacc
    60241 gttttgctgg tctactatgg tctctacatc ctacaaactg tagttcagta tgtaggcaat
    60301 cttctctttg cgcgcgtgtc ttacagtatt gttagggata ttcgtcggga tgcctttgcc
    60361 aatatggaga aactgggcat gtcttacttt gacaagacgc cagcaggttc tatcgtttct
    60421 cgtttgacca acgataccga gacgattagt gatatgtttt ctgggatttt atccagcttt
    60481 atctcagcag tttttatctt tctgacaacc ctttatacca tgttggtgct ggattttcgt
    60541 ttgacggctt tagtcttgct ctttcttcct ttgattttcc ttttggtcaa tctctatcga
    60601 aaaaagtcag tgaaaatcat cgagaaaacc agaagtctct tgtcagatat caatagtaag
    60661 ctggcagaga atatcgaggg aatcaggatt attcaggctt ttaatcaaga gaagcgcctg
    60721 caggcagaat ttgatgaaat caaccaagaa cacttggtct acgccaaccg ttctgtagcc
    60781 ttggatgccc tctttttgag acctgccatg agtttgctga aacttctagg ctatgcagtc
    60841 ttgatggcct actttggcta ccgtggtttt tctatcggga taacggtcgg gaccatgtat
    60901 gcctttatcc agtacatcaa ccgccttttt gaccccttga ttgaggtgac gcaaaacttt
    60961 tcaactctgc aaacggctat ggtttctgca ggtcgtgtct ttgccctgat agacgagagg
    61021 acctatgaac ctcttcaaga aaatgggcaa gccaaagtcc aagaaggcaa tatccgtttt
    61081 gaacatgtgt gtttctcata tgacggtaaa catccgattc tggatgacat ttctttctct
    61141 gttaataagg gtgaaaccat tgcctttgta ggtcatacag gttcagggaa atcgtctatt
    61201 atcaatgtcc tcatgcgctt ttatgaattc cagtcaggga gagttctctt ggatgatgtg
    61261 gatatcaggg atttcagtca agaagagctg agaaaaaaca tcggtttggt cttgcaggaa
    61321 cccttcctct atcatggaac tattaagtcc aatattgcca tgtaccaaga aatcagtgat
    61381 gagcaggttc aggctgcggc agcctttgtg gatgcagatt cctttattca agaacttcct
    61441 caggggtacg actcccctgt ttccgagcgt ggttcgagct tctctactgg gcagcgccag
    61501 cttcttgcct ttgctagaac agtcgccagc cagcctaaag tcctgatttt ggatgaagcg
    61561 acagccaata ttgactctga aacagaaagc ttggttcaag cttctctggc gaagatgaga
    61621 cagggccgaa caactattgc tatcgctcac cgcctttcta ctattcaaga cgccaactgc
    61681 atctatgtct tggataaggg acgcattatc gagagtggaa cccatgagga actcttggct
    61741 ctgggaggaa cttatcacaa gatgtatagt ttgcaggcag gggccatggc cgatactctt
    61801 tgaaaatctc tttaaaccat gtcagcttta tctgcaatct caaagctgta ctttgatttt
    61861 cattgagtac tagaaggaaa tccttcaaat tacagatttc tttcaccgcc ttttccattt
    61921 tgtggtataa tgaaaaatgt tgacaaatag tataataaaa acaaaggaga acagcatgct
    61981 gaaatgggaa gacttgcctg tggaaatgaa atcaagcgag gttgagtctt actaccagct
    62041 tgtctctaaa aggaagggtt cgctgatttt caagcgttgc ttggactggg ttttggcctt
    62101 ggtcttactg gttctaactt ctcccatctt tctcatcttg agcatttgga tcaagttgga
    62161 tagcaagggg ccagtgattt acaagcaaga gcgtgtgacc cagtacaact gtcggttcaa
    62221 gatttggaag ttccgtacca tggtgacgga tgcggataaa aaaggaagtc tggtgacttc
    62281 tgctaacgat agccgtatta ccaaggttgg aaatttcatc cgacgtgtcc gtttggacga
    62341 actgcctcag ttggtcaatg tccttaaagg tgagatgtcc tttgtcggta cacgacctga
    62401 agtgccacgt tatacagagc agtatagccc tgaaatgatg gcaaccttgc tcttgcaagc
    62461 aggaattacc tctccagcca gcatcaacta caaggatgag gacaccatca tcagtcaaat
    62521 gacggagaaa ggtctgtcag ttgatcaggc ctatgtggag catgttcttc ctgaaaagat
    62581 gcgctataac ctcgcctatc tccgagagtt tagtttcttt ggggacatca aaatcatgtt
    62641 tcaaaccgtg tttgaggtac taaaataaag tagtcataag aaaatgagta cagataaaag
    62701 gagcaaatca atgccaaatt acaatattcc attttcaccg cctgatatca cagaagcaga
    62761 aattgctgaa gtagcggata ccctgcgttc tggttggatc acaacaggtc ctaaaacaaa
    62821 agaactggag cgccgcttgt ctctttacac acagacacct aagactgttt gtctcaactc
    62881 tgcgacagcc gctctggagt tgattttacg cgttttggaa gtgggacctg gtgatgaagt
    62941 catcgttcca gccatgacct atacggcttc atgtagtgtc attacgcacg tgggagcaac
    63001 ccctgtcatg gtggatatcc aagcagatac gtttgagatg gactatgacc tgcttgagca
    63061 agctatcact gagaaaacta aggtgattat cccagtagag ctcgcaggga ttgtttgcga
    63121 ttatgaccgt ttgttccaag tcgtggagaa aaaacgtgac ttctttaccg cttcaagcaa
    63181 gtggcaaaag gcctttaacc gtattgtcat tgtctctgat agtgcccacg ctttgggatc
    63241 tacttataaa ggacaacctt ctggttctat cgctgacttt acttccttct cattccatgc
    63301 cgttaagaac tttacaacgg cagaaggtgg aagtgcgact tggaaagcca atccagtgat
    63361 tgatgacgaa gagatgtaca aggaattcca aatcctttcc cttcacgggc aaactaagga
    63421 tgctcttgcc aagatgcaat tggggtcatg ggaatacgat atcgttacac cagcctataa
    63481 gtgcaacatg accgatatca tggcttcact tggtttggta caattggacc gctatccaag
    63541 tttgttgcaa cgccgtaagg acattgtgga ccgctatgat agtggttttg caggttctcg
    63601 catccatcct ttggcacaca agactgaaac tgtcgaatct tcacgccacc tctacatcac
    63661 ccgtgtagaa ggagcaagcc tagaagaacg caacctcatc atccaagaat tggctaaagc
    63721 aggaattgca agtaatgttc actacaaacc gcttcctctc ttgacagcct ataagaatct
    63781 tggatttgat atgacgaact atcctaaggc ctatgccttc tttgagaatg aaattaccct
    63841 ccctcttcat actaaattaa gcgatgaaga agtagactat atcattgaga ctttcaaaac
    63901 agtttctgaa aaagtgctaa ctttatcaaa aaaatgacaa actacagtca agcgaaagtg
    63961 atcctgtccc taaaaagtct aattgagtgt aaaaactgtt gttttcaatt gataatagtt
    64021 tacacctgta gttgaggcct ctttctcctc agagagagaa tttttatagg attttccttt
    64081 cttgtgggag tcccgtggtt tgaaataaga tgtgagcaat ttagtgtagc atttagaatc
    64141 cttactagac atcatttaga aaatctagtg tcttgttcta gttttcaatt caccctattt
    64201 tttgaaagac gtgagtttcc atgagtgaga ttgtggaaac tcgcgtcttt ttttgttttc
    64261 agaatattgt tcaaaatttt gtgcctgtct ttcatgttct agtcattctt ttgcatgata
    64321 gaatttatag catgttgata ttataataat acaaatattc tatatgttta gtgatgcttg
    64381 ctatacatca ttagatctcc tgcgagacaa tctataaaac acttgtctac gattacctat
    64441 atgccctatt ccagtatttt agaagcactg catctatttt tatcgaggtt aaatctagct
    64501 tttatagaag gtctatttaa gaaatatatt gtagtgtttt agtttcaatc cgccatatga
    64561 gcgatattca ggtaaatatc cctggcgaat gcttgtatga caaggtattt gttctttcat
    64621 ttataattta caacatatca acaaatttaa atatagtaaa tgggatattt tatattcaag
    64681 ctaagaaaga tagcatcact tttgaatgga aggctaaaga gcaaactagg aagttggcca
    64741 tagatagctc aaaaccctgc tttgaggttg tagatatagt aaaatgaaat aagaatagga
    64801 caaattgatc gggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta
    64861 ttttagtttc agtctactat agaactgacc aagtcagtaa cctagactta gggcaaggcg
    64921 gcactgacct agtttgaaga gatttccgaa gagtataaat tttaatattt tcttgtgtta
    64981 ttccttgaca attcaatttg gaaaatatat gataaagata atgacagcgg tgtcattcta
    65041 tctattttaa gaaaagtaat aatcaattgt taaaaatagt aaaaaaattg gaggttctga
    65101 tgaaatattt tgttcctaat gaggtattca gtattcgtaa attaaaggtg gggacttgct
    65161 cggtactatt ggcaatttca attttgggaa gccaaggtat tttatcggat gaagttgtta
    65221 ctagttcttc accgatggct acaaaagagt cttctaatgc aattactaat gatttagata
    65281 attcaccaac tgttaatcag aatcgttctg ctgaaatgat tgcctctaat tcaaccacta
    65341 atggtttaga taattcgtta agtgttaata gtatcagctc taatggtact attcgttcca
    65401 attcacaatt agacaacaga acagttgaat ctacagtaac atctactaat gaaaataaga
    65461 gttataagga agatgttata agtgacagaa ttatcaaaaa agaatttgaa gatactgctt
    65521 taagtgtaaa agattatggt gcggtaggtg atgggattca tgatgatcga caagcaattc
    65581 aagatgcaat agatgctgca gctcaagggc taggtggagg aaatgtatat tttcctgaag
    65641 gaacttattt agtaaaagaa attgtttttt taaaaagtca tacacactta gaattgaatg
    65701 agaaagctac aattctaaat ggtataaata ttaagaatca cccttccatt gtttttatga
    65761 caggtttatt tacggatgat ggtgcgcaag tagaatgggg cccaacagaa gatattagtt
    65821 attctggtgg tacgattgat atgaacggtg ctttgaatga agaaggaact aaagcaaaaa
    65881 atctaccact tataaattct tcaggtgcat ttgctattgg gaattcaaat aacgtaacta
    65941 taaaaaatgt aacattcaag gatagttatc aagggcatgc tattcaaatt gcaggttcga
    66001 aaaatgtatt agttgataat tctcgttttc ttgggcaagc cttacccaaa acgatgaagg
    66061 atgggcaaat cataagtaag gagagcattc agattgaacc attaactaga aaaggttttc
    66121 cttatgcctt gaatgatgat gggaaaaaat ctgaaaatgt gactattcaa aattcctatt
    66181 ttggcaaaag tgataaatct ggggaattag taacagcaat tggcacacac tatcaaacat
    66241 tgtcgacaca gaacccctct aatattaaaa ttttaaataa tcattttgat aacatgatgt
    66301 atgcaggtgt acgttttaca ggattcactg atgtattaat caaaggaaat cgctttgata
    66361 agaaagttaa aggagagagt gtacattatc gagaaagcgg agcagcttta gtaaatgctt
    66421 atagctataa aaacactaaa gacctattag atttaaataa acaggtggtt atcgccgaaa
    66481 atatatttaa tattgccgat cctaaaacaa aagcgatacg agttgcaaaa gatagtgcag
    66541 aatatttagg aaaagtatca gatattactg taacaaaaaa tgtaattaat aataattcta
    66601 aggaaacaga acaaccaaat attgaattat tacgagttag tgataattta gtagtctcag
    66661 agaatagtat attcgggggt aaagaaggaa ttgttattga ggattcaaag ggtaaaataa
    66721 ccgttttaaa taaccaattt tataatttat ccggtaagta tatatcattc atcaaatcta
    66781 atgcaaatgg gaaagaacct gttatacgtg atagcgatgg taatttcaat attgtaacgg
    66841 agaatgggct ttacaatatt gtaacaaata atttaagtga taaaaacgaa aaagaaaaaa
    66901 acaaagagga aaaacaatct aattcaaata atgtaattga tagtaaccag aagaacggag
    66961 agtttaactc aagtaaagat aatagacaaa tgaatgacaa gatcgacaat aaacaagata
    67021 ataagacaga agaagtaaac tataaaatag ttggagatgg cagagaaact gaaaatcata
    67081 ttaataaatc taaagaaata gtagatgtaa aacaaaaatt accaaagact ggttcgaaca
    67141 agattatgga actattctta acagtgacag gaattggttt acttttgaca ctaaaagggt
    67201 tgaagtatta tggtaaagat aaataaaatt tgttcgatac aaggaagttc cgtagaaaat
    67261 gaggatattg taggttcaca aaatcagtat ttttggatta ttggtggagc tacagattta
    67321 tataattcta aagaggagat aggttattca gtctcagaag ttgtacatat tttatcagaa
    67381 agtttgtcgg ttaattgtaa agaatcaaaa actcttaaac aaatatttga aactgcttta
    67441 ctcgaggtta aagatgaaat cggtttaaac tcatatgaat taacagagta tagtaaaatg
    67501 aaataa
//
LOCUS       DAVLIK010000005        65178 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLIK010000005 DAVLIK010000000
VERSION     DAVLIK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65178
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.005"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(190..1938)
                     /locus_tag="VXE87_000319"
     CDS             complement(190..1938)
                     /locus_tag="VXE87_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841930.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPIFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTHLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1940..3664)
                     /locus_tag="VXE87_000320"
     CDS             complement(1940..3664)
                     /locus_tag="VXE87_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841931.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNRSYISAKRIKEVFVEAPEDIHSELEQKQVTSDRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIASVPQKVELFKGTIRSNLTLGFNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3724..4662)
                     /gene="msrB"
                     /locus_tag="VXE87_000321"
     CDS             complement(3724..4662)
                     /gene="msrB"
                     /locus_tag="VXE87_000321"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0841932.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4804..4881)
                     /locus_tag="VXE87_000322"
                     /pseudo
     CDS             complement(4804..4881)
                     /locus_tag="VXE87_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4957..5826)
                     /locus_tag="VXE87_000323"
     CDS             complement(4957..5826)
                     /locus_tag="VXE87_000323"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0841933.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(5828..7114)
                     /locus_tag="VXE87_000324"
     CDS             complement(5828..7114)
                     /locus_tag="VXE87_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0841934.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7265..8002)
                     /gene="mecA"
                     /locus_tag="VXE87_000325"
     CDS             complement(7265..8002)
                     /gene="mecA"
                     /locus_tag="VXE87_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0841935.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8202..9236)
                     /locus_tag="VXE87_000326"
     CDS             complement(8202..9236)
                     /locus_tag="VXE87_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0841936.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9265..10698)
                     /locus_tag="VXE87_000327"
     CDS             complement(9265..10698)
                     /locus_tag="VXE87_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0841937.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGILFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(10714..11700)
                     /locus_tag="VXE87_000328"
     CDS             complement(10714..11700)
                     /locus_tag="VXE87_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0841938.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNSIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11702..12805)
                     /locus_tag="VXE87_000329"
     CDS             complement(11702..12805)
                     /locus_tag="VXE87_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0841939.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLYQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12795..13640)
                     /locus_tag="VXE87_000330"
     CDS             complement(12795..13640)
                     /locus_tag="VXE87_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0841940.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSCILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13919..15193)
                     /gene="psr"
                     /locus_tag="VXE87_000331"
     CDS             complement(13919..15193)
                     /gene="psr"
                     /locus_tag="VXE87_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0841941.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15190..16038)
                     /gene="pheA"
                     /locus_tag="VXE87_000332"
     CDS             complement(15190..16038)
                     /gene="pheA"
                     /locus_tag="VXE87_000332"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0841942.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(16035..16511)
                     /locus_tag="VXE87_000333"
     CDS             complement(16035..16511)
                     /locus_tag="VXE87_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0841943.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16504..17787)
                     /gene="aroA"
                     /locus_tag="VXE87_000334"
     CDS             complement(16504..17787)
                     /gene="aroA"
                     /locus_tag="VXE87_000334"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0841944.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQDVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVAGGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17879..18217)
                     /locus_tag="VXE87_000335"
     CDS             complement(17879..18217)
                     /locus_tag="VXE87_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0841945.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18228..19331)
                     /locus_tag="VXE87_000336"
     CDS             complement(18228..19331)
                     /locus_tag="VXE87_000336"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0841946.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19341..20507)
                     /gene="aroC"
                     /locus_tag="VXE87_000337"
     CDS             complement(19341..20507)
                     /gene="aroC"
                     /locus_tag="VXE87_000337"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0841947.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20517..21584)
                     /locus_tag="VXE87_000338"
     CDS             complement(20517..21584)
                     /locus_tag="VXE87_000338"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0841948.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(21603..22457)
                     /locus_tag="VXE87_000339"
     CDS             complement(21603..22457)
                     /locus_tag="VXE87_000339"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0841949.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(22447..23124)
                     /locus_tag="VXE87_000340"
     CDS             complement(22447..23124)
                     /locus_tag="VXE87_000340"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0841950.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23121..24284)
                     /locus_tag="VXE87_000341"
     CDS             complement(23121..24284)
                     /locus_tag="VXE87_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0841951.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVTFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLTMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24969..26603)
                     /locus_tag="VXE87_000342"
     CDS             complement(24969..26603)
                     /locus_tag="VXE87_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841952.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFVVAILLVIAFSTSLTAFYNVFYESK
                     DLASYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTTAFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPILTLLGLSLYLGLPIISMIYLIMAWILASVIL
                     SCHHYFKDVKNLSINWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(26584..27333)
                     /locus_tag="VXE87_000343"
     CDS             complement(26584..27333)
                     /locus_tag="VXE87_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841953.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQDLSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSSSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDLDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRRDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            27512..28966
                     /locus_tag="VXE87_000344"
     CDS             27512..28966
                     /locus_tag="VXE87_000344"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0841954.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPIADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(29056..31674)
                     /gene="alaS"
                     /locus_tag="VXE87_000345"
     CDS             complement(29056..31674)
                     /gene="alaS"
                     /locus_tag="VXE87_000345"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0841955.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDSSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31696..32181)
                     /locus_tag="VXE87_000346"
     CDS             complement(31696..32181)
                     /locus_tag="VXE87_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0841956.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32456..32695)
                     /locus_tag="VXE87_000347"
     CDS             complement(32456..32695)
                     /locus_tag="VXE87_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841957.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(32940..34010)
                     /locus_tag="VXE87_000348"
     CDS             complement(32940..34010)
                     /locus_tag="VXE87_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0841958.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENDFQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(34007..34780)
                     /locus_tag="VXE87_000349"
     CDS             complement(34007..34780)
                     /locus_tag="VXE87_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0841959.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34777..35583)
                     /locus_tag="VXE87_000350"
     CDS             complement(34777..35583)
                     /locus_tag="VXE87_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0841960.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WLNLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35564..36721)
                     /locus_tag="VXE87_000351"
     CDS             complement(35564..36721)
                     /locus_tag="VXE87_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0841961.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36881..37786)
                     /gene="murB"
                     /locus_tag="VXE87_000352"
     CDS             complement(36881..37786)
                     /gene="murB"
                     /locus_tag="VXE87_000352"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0841962.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(37898..38650)
                     /locus_tag="VXE87_000353"
     CDS             complement(37898..38650)
                     /locus_tag="VXE87_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV0841963.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38660..39391)
                     /gene="budA"
                     /locus_tag="VXE87_000354"
     CDS             complement(38660..39391)
                     /gene="budA"
                     /locus_tag="VXE87_000354"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0841964.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39533..40804
                     /locus_tag="VXE87_000355"
     CDS             39533..40804
                     /locus_tag="VXE87_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0841965.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40824..41639)
                     /locus_tag="VXE87_000356"
     CDS             complement(40824..41639)
                     /locus_tag="VXE87_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0841966.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41796..42449)
                     /gene="phoU"
                     /locus_tag="VXE87_000357"
     CDS             complement(41796..42449)
                     /gene="phoU"
                     /locus_tag="VXE87_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0841967.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42461..43219)
                     /gene="pstB"
                     /locus_tag="VXE87_000358"
     CDS             complement(42461..43219)
                     /gene="pstB"
                     /locus_tag="VXE87_000358"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0841968.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43232..44035)
                     /gene="pstB"
                     /locus_tag="VXE87_000359"
     CDS             complement(43232..44035)
                     /gene="pstB"
                     /locus_tag="VXE87_000359"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0841969.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(44046..44930)
                     /gene="pstA"
                     /locus_tag="VXE87_000360"
     CDS             complement(44046..44930)
                     /gene="pstA"
                     /locus_tag="VXE87_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0841970.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44920..45837)
                     /gene="pstC"
                     /locus_tag="VXE87_000361"
     CDS             complement(44920..45837)
                     /gene="pstC"
                     /locus_tag="VXE87_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0841971.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45837..46715)
                     /gene="pstS"
                     /locus_tag="VXE87_000362"
     CDS             complement(45837..46715)
                     /gene="pstS"
                     /locus_tag="VXE87_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0841972.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47289..48593)
                     /locus_tag="VXE87_000363"
     CDS             complement(47289..48593)
                     /locus_tag="VXE87_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0841973.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48594..49367)
                     /locus_tag="VXE87_000364"
     CDS             complement(48594..49367)
                     /locus_tag="VXE87_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0841974.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49357..49635)
                     /locus_tag="VXE87_000365"
     CDS             complement(49357..49635)
                     /locus_tag="VXE87_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0841975.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(49635..50036)
                     /locus_tag="VXE87_000366"
     CDS             complement(49635..50036)
                     /locus_tag="VXE87_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0841976.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50246..50863)
                     /locus_tag="VXE87_000367"
     CDS             complement(50246..50863)
                     /locus_tag="VXE87_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0841977.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50853..51626)
                     /locus_tag="VXE87_000368"
     CDS             complement(50853..51626)
                     /locus_tag="VXE87_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0841978.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51637..52374)
                     /locus_tag="VXE87_000369"
     CDS             complement(51637..52374)
                     /locus_tag="VXE87_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0841979.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWKEIKKA"
     gene            complement(52379..53509)
                     /locus_tag="VXE87_000370"
     CDS             complement(52379..53509)
                     /locus_tag="VXE87_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0841980.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53593..53982)
                     /locus_tag="VXE87_000371"
     CDS             complement(53593..53982)
                     /locus_tag="VXE87_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0841981.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYALQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53998..54381)
                     /locus_tag="VXE87_000372"
     CDS             complement(53998..54381)
                     /locus_tag="VXE87_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0841982.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54382..55170)
                     /locus_tag="VXE87_000373"
     CDS             complement(54382..55170)
                     /locus_tag="VXE87_000373"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0841983.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55163..56098)
                     /locus_tag="VXE87_000374"
     CDS             complement(55163..56098)
                     /locus_tag="VXE87_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0841984.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPKLLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56228..56404)
                     /locus_tag="VXE87_000375"
     CDS             complement(56228..56404)
                     /locus_tag="VXE87_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0841985.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56544..57251)
                     /locus_tag="VXE87_000376"
     CDS             complement(56544..57251)
                     /locus_tag="VXE87_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0841986.1"
                     /translation="MKVIRVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57402..58430
                     /gene="queA"
                     /locus_tag="VXE87_000377"
     CDS             57402..58430
                     /gene="queA"
                     /locus_tag="VXE87_000377"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0841987.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(59091..60218)
                     /locus_tag="VXE87_000378"
     CDS             complement(59091..60218)
                     /locus_tag="VXE87_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0841988.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWCYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(60949..61500)
                     /locus_tag="VXE87_000379"
     CDS             complement(60949..61500)
                     /locus_tag="VXE87_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0841989.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61850..62674)
                     /gene="nadE"
                     /locus_tag="VXE87_000380"
     CDS             complement(61850..62674)
                     /gene="nadE"
                     /locus_tag="VXE87_000380"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0841990.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADTMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQELGADPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62671..64131)
                     /locus_tag="VXE87_000381"
     CDS             complement(62671..64131)
                     /locus_tag="VXE87_000381"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0841991.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64247..64735)
                     /locus_tag="VXE87_000382"
     CDS             complement(64247..64735)
                     /locus_tag="VXE87_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841992.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAGVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64725..64934)
                     /locus_tag="VXE87_000383"
     CDS             complement(64725..64934)
                     /locus_tag="VXE87_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0841993.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
BASE COUNT        19298 a        14802 c        12228 g        18850 t
ORIGIN      
        1 tgttttgagc tgacttcgtc agtcttatct acaacctcaa agctgtgctt tgagcaacct
       61 acggctagct tcctagtttg ctctttgatt ttcattgagt attacagtga acaatttttc
      121 tagctattgt aacaaaaaag tcactcgaag gcaacttttt tcgtccataa actttcaaaa
      181 gagaatggct tattcagaac taaaagccgc agctttttgc atttggtaat acttaccctt
      241 tctatccatg agttcttgat ggttaccata ttcaacaata tcaccatcta ctaagacaag
      301 aattaaatcc gcatcctgaa tggttgacaa acggtgagca atgatgaagc ttgtgcggcc
      361 cttcatgagt tttgcaaagg catcctgtac cagcacttct gtccgtgtat caatggaaga
      421 agttgcctcg tctaagataa gaatctttgg aatagccaga aagactcggg ctatggtcaa
      481 gagctgagct tggccgacag agagagattc tccagcattt tccaacttgg tatcgtatcc
      541 ctgtggcaac tgttggatga aaaagtctgc attagctgct ttggcagcag caattacttg
      601 ctctcgactg gcttcaggat tgccaaaggc aatattatca tgaatggtcc cttgtgtgag
      661 ccaggtttct tgaagcacca taccaaactg ctgtctcaat gatactcgtg tataatcata
      721 aatggattgc ccatccagca agatatctcc cgagctaatg ggataaaaac gcataaggag
      781 attgataaga gtcgattttc cagcacctgt cggaccaacg atggctacct tactaccagc
      841 tggaatatcg atagacaagt ccttaatcaa aattttttca ggatggtagc caaaagagac
      901 atgtttaaag gaaatagctc ccttaacttg gtcactggtc aagacttcct tacctgtttc
      961 agccacttca gggctatcta agactccata gatacgctct acgcaagcca gagcactttg
     1021 caactcagct agcactgaag aaatatcgtt aaagggcttg gtgtattgct gaacatagtt
     1081 caaaaaagtc actaaacgac cgacggtcaa ggttgaaccc atcatgatac gataagctcc
     1141 tactccagct aaaagggcat aaatgagtgc atttacaaag cgagtcgaag gattgaccgt
     1201 tgaagaataa aagatggctg actgagaata gcctgagtag ttgtcatgag cctcacgcaa
     1261 tctttggata aactctgttt gagcattgaa ggactggatt atagtctgct ggctaagcga
     1321 ttcttcaatc aaatgggtct gaatccccct cgtctctgtt tgcttctgga agagatgata
     1381 ggatctcttg gcaataaagc gtgaaatcac catggacagt ggcgtcaaca gcaagactaa
     1441 gagagtcatg aggagatgaa tttggagcat ggctagaata ctaaccaaaa tcatcaaaac
     1501 accaatgaaa aattggttaa aaatcatggt caagccagct gccaactgtt cgatgtccgt
     1561 ggttacacga ctgaccatct ctccattgcc ttgacgatcc gcaaaagcaa tcggtaaccg
     1621 atggagttta tggatgattc gctctcgtaa atctctggta taagagaaga ttagacgatt
     1681 atagaggaga ggattggccc attgtaccag agtatttcct attaccacca agagcatctg
     1741 gagaaaaatc tgccaaaaaa ttggtgatga accagccact aggacttggt caatgacctg
     1801 cccaatcaga ataggtaggt aaattgataa gccaacttgg gcaatagttc ctagaaaagc
     1861 taggaaaagg aggaagggat ggtttgctaa atctacggct aaacgtttga gcgtctggtt
     1921 tacagtttgt cgtttcattc tagtcctcct ttccatgttg ggatgcattg atttcacgat
     1981 agacttggct ggatttcatc aagtcatcgt gcttgccaac agctagcaac tcaccttttt
     2041 ccaagaggag aatctggtcc gccatctgta aagttgaggt tcgttgagag atcaaaatta
     2101 agctcgtgtt tggaaaattt tctctaatag ctttcaagag cttggactct gtaatggtat
     2161 ctagtgccga ggttgcatca tctaggatga gaaacggagc ttggcgcaag actgctcggg
     2221 cgatagacaa cctttgtttt tgtccacctg agaaatttcg cccccctgct tcaactagag
     2281 catccaagag tccttcctta tcactgacaa aatccttagc ttgagcaatt tccaaggcct
     2341 gccagagttc ttgatcagtc acttcttgat tgaaacctag agtcaagttg gaacgaatgg
     2401 ttcctttaaa gagttcgacc ttttgaggta cagaggcaat ccaagaccgc cactgctcca
     2461 aattaagagg actacgtcca ttttgataaa ggtcaatgtt ccccttgtct actggataaa
     2521 gtccaagtaa gagttgcacc aagcttgatt taccagaacc agtcccccca atgataccaa
     2581 ggatttgtcc ttgagtcata tcaaaggaaa tgtctctcag agaaggctgg gccgcatcag
     2641 gataggtaaa ggtcaattct tggacttgta aaacccgatc actggtaact tgcttttgtt
     2701 ctaattctga atggatatcc tctggagcct caacaaagac ttccttgatt cgcttggctg
     2761 agatatagga ccggttgaga gaattgatca acatggctag cttgaccaat tccaccaaaa
     2821 tctgtaagag gtaattgata agagcaatga gagcaccttg actgagcact cctccttgaa
     2881 ttgaaatata gccttgccag ataataacga gaagagttcc attgacaatc agataggtca
     2941 gaggtgttaa taaactagac cagaaacctg tcttttcttg taatctagca taaacttggt
     3001 taagggtttg aaaaatctgt aactctcgtt tttcttgacc aaaagcacga ataacccgca
     3061 tcccttgcaa ttgctggcgc gtttcctgaa ccagttggtc cgttttcttt ctgagactac
     3121 tgtagagagg attgaccaat cgcgataacc ctacaatgac aatggtcaaa atggcaacca
     3181 tgactaagaa ccagaaagtc aactcagctg agattcgata agccataaaa atggcaccaa
     3241 aaacgataat gggcgctcgt aaaaagagac gcaggaattg attgatacca gtctgaatct
     3301 ggtaggtatc cgaagtcaag cgagtgacca aactagaagt tgtcagacgg tctctgctgt
     3361 ccttgggcaa ggaaagaata tgacgataaa gatcgtttgt caattcctta gcaaaaccta
     3421 ctgctgcctt tgctgagtaa aattgagcta tcaaggccac taaaacgcca attactgcaa
     3481 agataaggag cagaccaatc tgcatccaga gatgaccttg atctccctga ggtaaagatt
     3541 ggtcaacaat cccagcaatc accatgggaa ccaagagctc aaaaacagct tctaacagct
     3601 tgaacaaggg ggctaaaatt gattccttga tgtagggttt gaagtaagat aataggtgtt
     3661 tcataaatcc cttttattca tattctagaa atgaagaaag tgggaaaccc caccctctct
     3721 gttttatttg tttaagtaag gcaatagata gccatatcct gctttttcca tctcatcctt
     3781 ggccacaaag cgtaaagaag cagaattgat acagtaacgg aggccgccta actcccgcgg
     3841 tccatctgtg aaaacatgac ccaagtgagc gctgcctgaa cgagaacgaa cttcaattcg
     3901 ctccattcca tggctcagat ccttgtaata atgaatcaac tctttggaaa tcggacggct
     3961 aaaacttggc caaccacaac ctgaagcaaa cttatccttg gcaaaaaaga gtggctcacc
     4021 tgtcgtaata tctacataaa tcccctcttc aaaggtttgg tcataggcat tggtaaatgg
     4081 agcctctgta gcagcttctt gtgtgacacg ataagactct tcagatagac tggccttcaa
     4141 cacctcttga ctaggctttt catagtttgc tgcatcaatc aatggcttat cagcatcggt
     4201 cacatcgata tgacagtaac ctgaaggatt cttcctgaga tagtcttggt ggtagtcttc
     4261 agccagaatg tagtggcgta attgctccac ttctactgca atctttcgac ccagcatgcg
     4321 ttcctgctcc tgcaccactg tgtagatagc tggcaaatct gcttcatcct gataataaat
     4381 cccagttcga tattggcgac cacggtcatt cccttgttga ttgatagata gaggatcgat
     4441 aactcggaaa taataaagta aaatctctct gagtgacact tccttctcat cgtaaatcac
     4501 ttggaccgtt tctgcatggt ctgtttcctt gagcaactgg taattggtcg tttcgacttg
     4561 accattagcg tagccaacac tggtttctag cactccagaa atgcgtgaaa aatattcctc
     4621 taggccccaa aaacaaccac ctgctagata aatttctgcc atctttattt ctcctttatc
     4681 acgtttttaa ctaatactct tcgaaaatct cttcaaacca cgttagcgtc accttaccgt
     4741 atatatgtta ctgacttcgt cagttctatc tgcaacctca aaacagtgtc ttgagctgac
     4801 ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag cagcctgcgg ctagcttcct
     4861 agtttgctct ttgattttca ttgagtataa acttcttttc acaaaaagga tatgaaaccc
     4921 tctggtcaag agtttcccca tcctatcttc tattctttat tttgcttcta cacggacacc
     4981 ttgggtatca actctcaagt catgcagttt tcctttgaaa ggttgctttt ccaattctgc
     5041 cttaattgtt ggcatcttgt catgagaagc cagaaccata actgtcggcc cagcaccaga
     5101 aaggtaggtt gcataggctc cattttcttt ggtcacttgc ttaatcatcg caaattctct
     5161 taccaagtcc tgacgatagc gctcatggaa gaggtctccc tcgattgctt gcccagcggt
     5221 caccatgtct cctgccaaca aggcagcaac cgctacattg gcgatagaac ttgcagcaac
     5281 agcttcctta taagacaatt ttttaggcaa gacactacgg ctgtcgcgag tacgtaattc
     5341 atagtttgga atgtaagcta gaaaatcaca ctctggaaag tctgctacga tagcagagac
     5401 ttgcccttca acagaacttg caataacgag attaccataa atggctggag ccacattgtc
     5461 aggatgccct tcaatcttgg tcgctaactg caatttttca tggtctgata agttgagttg
     5521 acccagttgg ttggctagtt caatcccagc aacgataacc gagctggaag aacccaaacc
     5581 gcgcgccaaa gggacatcac tggtcatttt caagcgtctt ggttgcaagt ctggtacaat
     5641 ttgtaaagcg attttgagca agagattacg ctcatcatgt ggaatccatt tgccaatctg
     5701 gtgttcaatc agccactcat ctcgttcttc gcagacctca atttgaagat acttggttac
     5761 agctacaccg accgagtcaa aacctggccc gatattggca ctggttgcag gtacaataat
     5821 cttcatctta ttctcctagc accttgaagg tattcaagag gtcgaattct gaaaccttct
     5881 tcaattcagc tgagacattt tcaagctggg ctttattaat cttgtgtgtg atgataacga
     5941 cacgcgcctt gtcaccctct ttgccatctt gaaggatttg cttaaaggaa atatcttgag
     6001 cattgaagat ttcagccaac ttcaagacct gaccttttga gtctagagcc aagattgaga
     6061 aatagtagtt tgctttgaca tcttcaggat ttgccaagac caagtcacgg ctatattcgt
     6121 tgaagtcttt gccaatagta ccatcattca aacgacgaac gatacggaca atatcagcta
     6181 caacacttgt tgcagttggt ttttgacccg cacctggtcc gtagtacata gactcaccaa
     6241 taccgataga ttctacaaag acagcgttca ttacgccatt cacactagca agtgggtgcg
     6301 ctttaggtag gaaggttgga gtcacttctg cagcaatacc tgaagaagtt tcctcaatag
     6361 aaccaaccaa tttcactacg taaccaagct cttgagctac agctacgtct tctggtgtga
     6421 tattgcggat tcccttgtgg gctacatcat caaaggcgat cttcatgcca aaggcaaatt
     6481 ggctcaaaat aaccatcttg taggctgcat caatcccatc tacgtcattc gtcggatcgc
     6541 tttctgcaaa tcctagacgt tgtgcttccg caagagcatc atcgtaagac cagccttctt
     6601 ccaccatctt ggtcaccatg aagttggaag ttccgttgac tactccaagc acgcgcgtaa
     6661 ttttatcaga agccaaggaa tttgctaaag tacgaagaat tggaatccca ccagcaactg
     6721 ctgcttcgta gtaaagtgct accttgttag cttgagcgat ttctagcaat tctgcgccat
     6781 ggacagctaa aaggtccttg ttagcagtaa caacgtgttt tccagcttcc aaggcacgag
     6841 tgataaaggt tttagcaggc tcaatacgcc ccatcaattc cactacgata gtaatatcct
     6901 ggtctgataa aatatcatcc acattggtta caaagttaaa gtcattccct gctgcaagca
     6961 agcgattttt ttcatcttca tccttgacca ataccttagc aactttgata tctgaatgtg
     7021 ctgattgatt gatttttcct ccattttcct ttaggaggaa aggcacacca cttgcaacgg
     7081 taccaaatcc cagtaaagca attttaactg tcatctttat ctcctcgaaa ttttctaata
     7141 tagccattat aacagaattt tgtgaaaatt cctattatag taaatcacta tttcagtata
     7201 aaaagaaaaa acgaatcaga cgattcgctc ttcttaaaat ctgaaaatag ctttccagaa
     7261 aggattagcc gattttttgc agattgagca ctgcatcgtg actcatcaag acttgaccat
     7321 actcttgtaa gactgagcga ctgatatcac tatcgtctgc aaactcgcgc atacgggcca
     7381 acagccaagc tggatatggg cttggatgat tttcaatatc cactaaaatg gtcaaataat
     7441 agcgctcgtt cattttgtag agttcagaag tttccatttc aaaagtcact gtcttggcaa
     7501 aaactaccaa gtcagccaac ttagcaaaag aaaggatgta gtagatgtaa ggttctttct
     7561 tactctcagc ttcttgttca gcctgctctt gctcttcttc cttggcttca acttgctcaa
     7621 gagattgaat ggcttcgata tcatccttgg ttttgtctgc gatgcttttt tccagggttt
     7681 tgataaattc atctggagac atttgagcca attcttccat atctggcaaa tccgataagt
     7741 cttcaaaatc tagattttgg tcaatctttg acttggtcac aaagacatct accttatcag
     7801 gttttggagt cacacggaag ctcaacatgc ctgtatccag aaagctatca ggcatctcta
     7861 gctcatccaa gatagcataa aagaactctt ctgttttttc ttgaggaacg agaaagtcag
     7921 caatctccat tccacgatcc atcaaatcct ctaaagacat cgtgattttt aaagttgtat
     7981 cactaatttg tttcattttc attgctagta acctcatact ttcagttcta tctattatac
     8041 tagattttta cgattttatc aaaagaaggc tcctctatac ggatagattt tccctagggt
     8101 ctttctatag gagactccaa gagaaaattt ctgcagacag atagaaaaag ccttcaaaat
     8161 cggctaagag ccgattttga agaccttata catcagaata cttataattt aaaggttgct
     8221 acaccgagga tagaacgatt taagtttctg agaatttgaa gactttgctc aaatttctta
     8281 taacgagtca ctccgtactc ttcaacaaga aggactgtat ctctttccaa aagagatgat
     8341 acatcctgta aatctacaaa atgcattcct tttaaagctt cttgactctg tttcaattta
     8401 tctaggatag ctttatttga gctaacgatg gtcaattcct gtccagtatt tttgtatgac
     8461 aaaacatctg ctaggttagc aattgttgta atctctgtta caaaatcaat ttgatactga
     8521 gaaaaatcac ctactctatt gattgttgga ttaaagagat aaactaacac atttcccatc
     8581 acaaccaaaa tcacacaaac cactccaata acaactaaac gaagaatcag atttttcaca
     8641 tttaagccaa gcgctgtttc accatttgcg ttcaattctt tagagttgat ggtttccagt
     8701 ttttcaattt ttacatttgc ataggcatgt ttaaatttct caatcaaccc atcaattttt
     8761 ttctctaaca agtcattggc atctttactt gatgtcaaaa ttttcacacc aacccctgca
     8821 tcgtcaatca tatagtagac ggtcaatttt ttccaccaat agtcattcgt tgaatttttc
     8881 aaggttgttt ctgtcgtgtc taattcactg gcaatttttt tcaactcact gggttctaca
     8941 tcattgaaaa gataagctcc attcaaatta ccatcaatca atttcccata aaaatcacta
     9001 taaccaccaa tttgatgatt caaaatcgtt ttggccgaat cttctggagg agtgatttta
     9061 tagataagat aagttgaata acttgttgta tctttgacag tgtttttatt cctaactgct
     9121 ttaattgtaa atggtacagc aatgagagca aataaagcga tgagagctaa aatatttgct
     9181 tttcgttttt tataaagatt tgcaaacaaa tcagctactg aataatgttc aaacatgatt
     9241 tttttctcct ttgtttagta gatactagtt ttcctttgta agcatttttg ctacaaatat
     9301 aatcacaaga acaattcccc agaattgcat tgtaaataaa ttgaagaaac tttctgaaaa
     9361 gctgcttctt ggcataaaga atagattatt caagatgagt agggataaag caaataggat
     9421 tgtccttgag cgataggcta cttgcagcat ggctataaat aatatgccga gtaagaaact
     9481 aagcagaaag actccaatca taccatagtc ggtatacaac tccatgatat aactacttcc
     9541 gataccatgc cctttcaagt attccttgtt caagacaaga taggatagat tgtgggcata
     9601 actattacta tcaatagcta gttccacact attggttgta tgttcaaagg cttttcctcc
     9661 gaaaatggct cccaaactcc cccttgcaaa ataatcaaga acaggaccaa aagtaaaatt
     9721 acggaaatct cggtaaggga ggctactgtt aaatagaaaa cctcgagcca gaacaccaaa
     9781 actagtccct tgtttataga taaagtcaag taagatatcc cagaaacctg tatgggaaac
     9841 ttggacatta tcccgtacat aattgagtac tcccatcgct aacatgagaa taggagaacc
     9901 tacaaaaatc gctaactttt ctttaaaccc aatccatttt cctttttcag cttgctcccg
     9961 cataaagtaa taaacaaaag caaataaaat acttaaaata aagggatttc gtgtcccaat
    10021 tgccaaatga atagtgttag ctgcaataaa ggagacaagc actgctgtgg cctgcaattt
    10081 ctttggcttg gttgccagat acatacacat tgcatagacc gtaaaggtag acaaaatgta
    10141 ggtaaaataa ggcagtttac tttcaaaatt tgcatagtag gcatagtagg aagtctgcaa
    10201 acgatacaag agccgttcaa ataaccgaat gaaatagaaa ggataagtta gaagaaaaac
    10261 tcctagtgat acaaagcgta accgcttgat ataaacctct tttagagaat ttcctatatt
    10321 tgctactttt attttcttcc tagctatgaa gtaacgagcc aggacgcctc ctgttgtcaa
    10381 gcccagaatc gaaaccatga caactataaa ggcaaaacga taggctattg gatgataggt
    10441 atccaaagca ccatccctaa aataatcaat ggtcggtctt gataccagaa atacaaaaat
    10501 ggttaaatag aaaataaaat ggattaagta atacttgata tcattccaac aagcaatcaa
    10561 gctactaacc aacaagaaca ataaagtaga aagtaagcta acattattat tattaaacag
    10621 atacacaatt ccacttacta gcgtcaaggc ataactgact atggtcaaac taaataataa
    10681 tcgtttccca tcaatcactt ggtcaccccc gttctaatgt aattttttag atttttcaat
    10741 atttttcagt aataagaatc ggtataagga aatatttatg aatagggcca aagcactaat
    10801 tcttctcccc ttacggaaaa ttgaattcct agaaatagca aaggcatggc cttttaaaaa
    10861 acgatgaatc tgagaatagg cttcaaactg tttatactga tcatctagca acatcttatc
    10921 cagaataaag aagtgggcat aggccaatct gaaaaaagcg acctctttca agtcaggata
    10981 gtttttcaca acttcattat aaaacttttg gtagatatca atataggcta aatccttctc
    11041 tgcatagggc ttggtcgtaa tactatcccc tctatggaaa tagtaataat agggtttagt
    11101 attaaccaca tacttcttgg ccaacttgat taaatcaaaa tggtaatagg catcttcgta
    11161 aatcaacccc ttaggaaagg ataggtcagt tgcaatctgt ctcttgatta gcttattgca
    11221 aatcgtccca ggtatttttt cacctatgag gtattccttt agaaatgttt gagaatcaca
    11281 gacaaaatag tcatcctgat tggctgactg tgggctttca tcattagcat agacattcat
    11341 gacaccacag ctcgaaacat ccgcatcttc ttgaactaat tgctcatata agctctgaat
    11401 catttctgga tggatataat catctgagtc aataaaaatc agataatccc cgtgagcctg
    11461 cttcatccca tcatttcgtg cttgcgacaa tccttcgttc tttttatgaa gcactgacac
    11521 cctgtcatct tgttcagcga ttgaatcaca caagcgacca ctttcatctg ttgcaccatc
    11581 atcaacaaga ataatttcca gattttgata ggtctgcttc tgaatggaag ctatcgattt
    11641 ttctaggtac tgcgccacat tatagactgg cacaatcaca ctaattaatg cagtttccat
    11701 gctactcctc taatagtttt tctacttgtt cgatttgttt tgtaattgta aattgttgaa
    11761 tgaattggct agcctcatcg acatcaaagt ttgaggcaga agtcatgtaa ttagtaatcg
    11821 cctgagctgc ctcttgattg ctctcaatga tttgtccaaa tcgtccttct tgggataatt
    11881 cctcagcccc tccaacgtcc gtagagataa aagggagtcc cagactcaag gcctccacat
    11941 acactccagg aaaaccttct tgtttagaca tagacaagag aactttcgtc tgagatagat
    12001 actgataagg atttttttga taaccaagga aatgtacata gtcctcaatc ccatactctt
    12061 tgactcgttt tttcagttcc tcttccatat caccagcccc gataaaatag agatgatagt
    12121 tttttccctc ttggtataat aatcgtatca cttccactac acggtcagaa cccttatttt
    12181 cctcaatccg tccgatagta cagatacttt gaggagcaat ctcgatatcg atcttctctt
    12241 gagatttttc tagaatagtc tgaaaatcat atccattgta gattgtctgt aatttagaag
    12301 cataatctgg ataaacttcc ttgatagaat tgctggtctt ttttgaaatc cctacaattg
    12361 tattcgcagc atccaactgg cttctatgtg attctctttt agagctatcc ttaagaagtt
    12421 cttcaatact tccatgaatc caagatatct tcttgacttc tcttctttta gagaacaaca
    12481 gtggtggatt cataatggta aaagaaactt caacatcata atcatctttt acaagcaaac
    12541 gacgagtcag tcttggaaaa taaattctca ttctccacaa aaaagctcgt aaccatctgg
    12601 tttggcgata atcttgaagg gattttaaaa tgcgtacatg ctttggaaca gattcatatc
    12661 ccttgtcaaa gtgctccatt tcaagaatat caatatcata cttttctgga tccagatttg
    12721 aaacaatagt tgatagaatc ttctctgcac cacctccaag agaaaaagac cacataaaaa
    12781 ataagatttt tttcttagcc accatattct cccttgtatt ctgtataaga cttatccata
    12841 tcagcgatga cagcatcatg atgcggtacc tgcttgtctg ctggtggagg cgtcatataa
    12901 tccccaaaag cagttctgag atagacatca tagccgattg gaataggcat ctctgttcct
    12961 tcaaatggca agaaaagatt gtcttcaaaa gatgtgattg ggtacttgtt tctcatgtag
    13021 ccaggacctg agcataattc tgtaatgcca tcacaatcag ccaaatcata cttagtcatt
    13081 tctttctcag cttttttcca gatgcgataa cggagagatt ttggagtcaa acccagtaaa
    13141 atgcaacttc cccatttcat gagagcacca tgcttttctg gaatagtttg cgcacaaaag
    13201 agtgaataaa tcaaggccca acgaacctgt tttttccgct cagctggatt tttcggataa
    13261 taatccaaag gcaaaacatc caaggccaga ccatgtggca aatccaaatc ctgctgataa
    13321 ggcttgatac aggtggtttt cttgtcacga atggtaataa aaagattacg atcaacaaaa
    13381 tccttgtgac tctttgacaa gaaataacgt tcatctgcat aacgaggcca taattctgct
    13441 aatttctcat aatctttacg aggcataaaa aagtctaggt cgtcgtccca aggaataaat
    13501 cccttgtttc gaagggcacc aatagcgcct ccgccacaga gataacagag caaatcatgt
    13561 tctttacaaa aggccacaaa atattcagcc atctccagac tacgagcctg aattgctttt
    13621 aaatcagtca tattgttcat tattctttct atcgtatcgt ttcattatac cacaaacaag
    13681 gggtgaaaat ctattgcaga ctgtaaaaaa tcaaagcctg actgctatcc aaatagctat
    13741 caaactttga tttttctgtc ttatactctt cgaaaatctc ttcaaaccac gtcagcttca
    13801 ccttgccgta ggtataggta actgacttcg tcagtcttat ctacaacctc aaaactgtgt
    13861 ttttagcagc ctgcggctag cttcctagtt tgcactttga ttttcattga gtattatctt
    13921 atctcaagcc catttgagcg agcttggttt gatatttgtt ttgatcaacc agcaagccca
    13981 agcctccata aacatcatag gcatctaccc agtcacccag ttctggaatc gtcaattttt
    14041 caataccatt ttttgctcca tccaaaacag ataaaccgtt tgttaggagg aaagtataag
    14101 gtacgttggt tgaggtcata gcaaaaacct ttccaagagc ttcagaacca gtgaaaagtt
    14161 tagtgggatc tttaatttgc tctaaaattg ctgttaaaac ttgttgctgt ctttttgtac
    14221 ggccgtaatc cgcctcatca tcatcacgga aacgagcata attgagcagg gtcgagccat
    14281 tcatctgctg ttttccgact ttaatggttt gggttggaga ctcagtctcg gtagcatata
    14341 aatcatctcc gactgtagct tctgttaggg gacgcccatt caatgttgaa aattgagcat
    14401 caatcgtcac cccatcaggg aaaagcgtgt caatcgctgt ggcaaaggcc tggaaatcaa
    14461 ccaaggcgta gtacttaatg tccaagtcaa aattatcttt caagacttgg cgaaccattt
    14521 ctgccccttt ttgcccctct tgttctccta actcgtaggc tacgtttaac ttgttatctg
    14581 tctgttttct accattaatc acttgactat aaccatctat atagaccaaa ttatcacgca
    14641 tgaaactgac tagcttcatt ttcttatctg agcccccgac atttaatacc ataatagagt
    14701 cagttcgtgt ctcaacactg ttctggccga ttcgaccatc agtacccatg attaaaatat
    14761 taactccatc tctagtgtcc tgaccattaa agacttctac ttgagctgcc cgggcatcag
    14821 cagttttctt tgcgctagca tcttggtaac cacgcaaaaa catgaatacc atggccaaag
    14881 ccacacagac caaaagtgaa aaaatcacca taaaaattcg tttaagacgg agcttccgtc
    14941 ttttcttttt tggagggaaa gagagtgctt gtgatttgga ttgtgagcga ctccggttcg
    15001 catagcttgg taagtcaacc tgctcttctc tttcttgttc caagctagag ctactatttc
    15061 ccctagcaag agttagcttt tcttgcaaat aggcaaactc atttttttct ctctcattga
    15121 gatagtgaat attttttagc aaataatcat aacgcaactg ctcatgatga cttaagggat
    15181 tttctttact catcttctct cctttccatg gtctgatatt ggataaatag gataggcacc
    15241 cagaatttta tactggattc caatcgcttc taattctttt tgggcaaagt ggaccaagtc
    15301 cttatcggta taatccacat cgataatgaa aaagtattca cccagtgctg tcttgagtgg
    15361 acgactttca atttttgtca agtcaattcc tcgccaagca aaggtcgaca gggccttata
    15421 aagtgcacct ggaaggttgt caggtaatgt caaggccaaa ctcatctttt cagtttgtgc
    15481 ttgcaaggga atactaggct tttcagctcc tagaacccag aaacgtgtga aattggcttc
    15541 catttcctga atatcctcgg caatcagttc caatccatat tcttcagcag aacttctagg
    15601 tgcaactgct gcaaagggct ggtctggatg ttcggaaata aaacgggccg cataagctgt
    15661 actagctgtt acctcgattt gagcctctgg atattgttca tcgatgaatt tctttccttg
    15721 agccaaggcc tgtggatgtg aaaaaatctt ttcaatctta gtatggcctg gaaccaccat
    15781 caactgctga tgaataggct gaacgatttc tgctactgct tggatgtgag cctgatgaaa
    15841 aagatagtcc aaggtttcat gaacactacc ctcaatagaa ttttcaactg gcaccacaga
    15901 atagtccact aatccttgct cataagcctt gatgacatct gtaatgttgg caaaagcctg
    15961 caattcctca tgaggaaaag ctgtctgcac aacgtggtgt gaaaatgatc ctttgggacc
    16021 tagataagca attttcatct tagttcctct ataatttcct ctgggcttag cttggtcaca
    16081 tccaaaaccc gactagccac ttcctcatac caagcctgtc tttcttgaaa aatagctact
    16141 agttcttcct tgctattatt tagaaaaagc ggtcgctgat tgtccttatc agctgcgata
    16201 cgttggtaga gggtttcaaa atctgctttc aggtagatgt tatctgtatt agtcttgagt
    16261 aagtcacgat ttctctgaga aataaccact cctcctccag ttgacacgac ttggtctgtt
    16321 tgtagtaaat cagctaggac ttctgattct acctgacgaa aggctgcttc tcccttttca
    16381 gcgaaaaaat tcgcaatgga catacctagg cgcttctcaa tcagagcatc catatcaagg
    16441 taattagggt ccaagcctct tgcaatagtc gattttccag cccccataaa ccctaataac
    16501 accttagcca tgaatcaagc tctccaaatc atcaaagaaa ctaggatagc tggtattgat
    16561 ggcttctgca cggtcaagct ccacctctcc acctgcaacc aatagggctg cgatagctgt
    16621 catcatgccg atacggtggt caccaaacgt attgactcta gcaccgtgaa gagctgattt
    16681 tcctttgata atcatcccat ctgccgtagg agtaatatct gctcccatac tatttaaggc
    16741 gtctgccaca acctgaatac ggtctgtttc cttgaccttg agctcctcag catccttgat
    16801 aactgttaca tcttgggctt gggtcgcaag tagggcaata ataggcaatt catcaatcaa
    16861 acgtggaatc aaagcgccac aaatctctgt tcctttcaag tcagaagact caacaatcaa
    16921 ggttgcagat ttagcgactg gatcgatttc agttatttcc aattttccac ccatggcacg
    16981 aatgacatca ataataccgg tgcgagtttc gttgatcccc acattctgca gcactagacg
    17041 agaatttgga gcaatcaaac ctgcgactaa ccaaaaggct gcactggaaa tatctcctgg
    17101 tacgaccacc ttctgtcctg tcaatttttg tggcccttgg actgtgattt tcttaccgtc
    17161 cacacttaaa tgaccaccaa attgttgcaa catatcttca gtatgattac gggtgtactc
    17221 tttttcgata ataactgact cccccttagc ttgtaaggct gcaaacatca aggctgactt
    17281 gacttgggca gaggcaattg gcaactcata atgaataggt cttaggtttt tcgtcccttt
    17341 taagcgaagg ggaggcaagt ctcgttcagt ttgtcctgaa atgctgacgc ccattttttt
    17401 cagtggaagg gtcacacggt ccataggacg tttggaaaga ctatcatctc caaacatctc
    17461 tacttcgaaa tctgcaccag caaggacacc tgaaatcagg cgaatcgagg tgccagaatt
    17521 tcccatatta agggcatttt gcggcgcttt taagccagcc atgcctacac cttgaatggt
    17581 aataacccca tctttatcct caatttcaac accaaggtca cgaaaaacct gcatggtcga
    17641 aagaacgtct tcacctcgca gaatatcata aaccttggtc tcaccctcag ccaaacttcc
    17701 aaagataatg gaacggtggc tgatagactt gtcacctggg acgcggatac taccatgtaa
    17761 atggcgaatg tttgttttta gtttcatact ggacctcata cttgcaatac ttttacctat
    17821 tttatcataa aaagccagaa attccttaaa aattcctgac tttaggatag ttcttttctt
    17881 atttcagcaa ttctgaaact ggttcaaaaa caattttttc aatgtcagaa aggtaaatgg
    17941 ccaattgttg ttgcttggta aagaattctg acaagaggct atttccttga atctgtttac
    18001 caaagccttc catcttagct tggaaggacg catctggcat ttgacctgtc tgtgctagtt
    18061 tttgaatttc ctcttgaaag gcaagatatt ctgtaaagat tttgcttgcc tcagcatctg
    18121 ctgcaatcgc atctttagct gctttaacag ccttgtattc tggtaatccg cgtagaccgc
    18181 gactgagttc gtttgcacta tcgtaaatat ttgacatgtt cttctcctta tttgatgacg
    18241 actgtatagt cggtattttc tgttatgaga tgctcagctc tttccaagtc ttgagcattt
    18301 ttaaatgaaa tttgtaggat tccgtgaata tcctcacgat tttcctcgtt gatgtggatg
    18361 ttaaccaagg aagttccacg tagcagttcc aaaatccgca ggatgacatc ttcttcatca
    18421 ggaacgtcaa catagaggtc gtaagagcta tccacaccac cacgcttatg gatttccatg
    18481 gtctggcgtt gttcacgcgc ttggttaaaa aagttccaaa tttgctcttc atctccctta
    18541 ctaatggcct gaccaatcac ttccaaacgt tccttgaaat cctcaattct atccagaatg
    18601 gtctcgctat tggacaagag aatggaggtc cacattcctg gctcgctttc cgcaattcgg
    18661 gtcatatctc gaaaaccacc tgccgcaaag cgccttgcca tctcatgctc ttgagcatag
    18721 accgcagtct gctccatgag actagaagcc aaaatatgag ggaaatggct aatctgagaa
    18781 gtgacacgat catgctcctt ggcatcaatc tcgataaaac gagcatgaag acctgaaagc
    18841 agatccttca tttccttaag cgtgtcctga cttgtcaggc ttgaaggtgt aaagatataa
    18901 taggcatttt caaaaagatt gacatctgcc gaagcagccc ctgtcttgtg actaccagcc
    18961 atgggatggg ccccgacaaa gcgaacagac ttgccagcca aatactgctc cgccgcatcc
    19021 acaatggttg acttggtcga accagcatct gaaataataa cgccttctcg caaatccaaa
    19081 ttggccaact ccttaatgaa agcaatagtt tgtttgattg gcaagctgag gataatgaca
    19141 tctgccaaag gagcaaaact agcaaaatca tccgttgcac ggtcaatcat accttctttc
    19201 aaggcgatat ctctcgaagc ttgactacga ttataaccta aaatttcata atctggatga
    19261 tcgcgtttga taccaagtgc catagaggct ccaatcaacc caagacctgc gatatagatt
    19321 gtttttgcca taggaactcc ttaatagttc tttgtatagt ctcggtgttt ggctaccgct
    19381 tcttttagtt cctcaagatt atctgatgag aatttttcga ggatttcttg cgccagaacc
    19441 gttgctacaa ctgcttccat gaccattcct gcagctggaa gagcagtcgg atcacttctc
    19501 tccacggttg ccttgtaagg ttcgtgggtt tcgatatcca cactcataag aggtttataa
    19561 agagtaggaa tgggtttcat gaccccacga acaacgatgg gttgcccatt agtcatacca
    19621 ccttcaaaac cacctagatt attggtacgg cgagtataac cgtcttcttt agaccagaga
    19681 atttcatcca taacttggct gcctttacga taaccagcct caaagccaag accaaattcc
    19741 acccctttaa aggcattgat agagacaaca gcttgagcca atcttgcatc caattttcta
    19801 tcccattgga cataggaacc aagaccaact ggaacgcctc cgacgactgt ctccacaacc
    19861 ccaccgatgg tatcaccatc acgtttgatt tggtcaatat agtccttgat ttcctgttct
    19921 cgttcttggt tgacaataga aacttcagac tgggcagctc tttgcttaat ttcagcgact
    19981 gtcagatttt caggaacatc tatttcctta ccaccaaaga ccacgacatg gttggcaatc
    20041 tccatatcca gctcagccaa gaggcgtttg gctactgcac caactgccac ccgcatggtg
    20101 gtttcacgag ctgatgaacg ctccaaagaa tttcgcaaat catcaaaacg gtacttaatc
    20161 cccccaacca aatcggcatg acctgggcga ggatgagtaa ttttccgctt gcttttaagg
    20221 cggtcttcaa tgtcctccgc agacatgatg tccagccatt tctggtggtc cttattgatg
    20281 acatccatag taataggcgc ccctgtcgtc ttcccgtggc gaacgcccga agtaaagaca
    20341 acctggtcac tctcaatctt catacgacca ccacgaccgt agccaccctg acggcgtcta
    20401 aggtcctcat tgatatcctc agctgtcaat ggaagtccag ctgggattcc ctcaataata
    20461 gctgttagac gggggccgtg tgattctcct gcagttaaat atctcataca ctctccttat
    20521 tttaccaagt agtctttcat ctcttccaga gaaactgggt gaatgatcgc tgaaccaagc
    20581 tctggcacca agaccaattt caaggtgtta ccacgcgctt tcttgtcatg agtaagagcc
    20641 tgataaagct tgtcaacttc ccaattttca tagtcaacag gcaagccgaa tttctgacac
    20701 atctctgtga tagattgggt aatgccagct ggcatgaggc ctttttcctc agcaaccttg
    20761 gaaatctgta ccattcccat ggcaacagcc tctccatgca tgaccttgcc ataaccggca
    20821 gtcgcttcga tggcatggcc aatagtgtgg ccaaaattga ggtaaagacg aataccattg
    20881 tccaactcat cttcaaccac catcttgcgc ttcacctgac aagaatgttc aatcaaggtc
    20941 tctgcatgtt ccaaaatact ctcaacagaa ccattcagtc ccgtcaagag agcccacagt
    21001 tctggatcct caatcaagcc atacttgata acttcaccca tcccttcaat caactctctt
    21061 tttccgaggg tttcaagaac aagtggatca atcagaaccc catctggttg ggcaaaggtc
    21121 cccaccatat ttttagcaaa tggtgtgtta acgcctgtct ttccaccgat agaagaatca
    21181 acctgagctg tcaaactagt cggaatctga acaaagtgaa taccccgcat ataggtagag
    21241 gctacaaagc cagccaggtc cccaacaacg ccaccaccaa gagcaacgat tccatcgcta
    21301 cgagtcagac cttgcttgac tagaaattca tagactttct gaacagtagt taaattcttt
    21361 ctttcttcac cttctaagaa atcaaaaaca gctacctgaa aaccagcatc ttctaggctg
    21421 agcttgacct tctctgcata gagagaggct acatggttat ctgtcacaat gactaccttt
    21481 tgcggttgcc agagttctcg caaccactga ccagcctggg ccatacaacc tttttcaatc
    21541 tgaatatcat aaggatgatg aggaatatcg attctgattt tcataggaga gtctcccttt
    21601 ctttattggt atttttctgt taaagactgc caaatctctt ctgtcggcat ttccttgcct
    21661 gtccacagtt gaaaagcttc tgcagcttga tagagtaaca ttcccagacc attgactgct
    21721 ggattgccct gacttctagc ccatttcaaa aacggtgttt caaagggttg gtatatgata
    21781 tctgcaacta agagagtttc tggtaagact atgttttcag gaacaggaga ggattggcca
    21841 tccatgccca cactggtggc attaactagc aaatccgact cggcaatcct tgcttgcagt
    21901 tcagaaacat attctaaagc acacaaatcc actttaaagc ctgtctgctc ctgtaacttg
    21961 tctaggtaag gtcttgtttt ttccatagaa acggaacgaa caaagaccga aatctgactg
    22021 acgccatcca aaatagcctg tgccaagatt gatttagccg caccacctgc acccagcagg
    22081 gtcatctttt tacctgaaat tgtaaaagaa ggcaagcact taaaaaatcc cttgccatct
    22141 gtattatatc caattaaatt gccattctca ttgacaaccg tattaaccgc accaatcaag
    22201 cgcgcttcat cgctcagctt atccaaataa ggaatcacct gctccttata gggcatggac
    22261 agattgatgc caaacatctg gtagcgacga atattggcca ctgtttctac caagtcactc
    22321 gcttcaatct cccaagccac ataagcaccg ttggtatctg tcgcctcaaa ggctctattg
    22381 tggatgaagg gagaaataga atgcttaata ggattggcaa caactgcagc taaacgtgta
    22441 tagccatcaa gcttcatcca aaatctccct gatttttttc atgctagcta gagaaatctg
    22501 cccaggggca ctaacctcat ccagactggc aaaagaccaa ctcgaaccag tcacatccgc
    22561 agtgatacga gagaccttgc ccaccttacc catagaaatg gtcacatatt cctgttcagg
    22621 attgagggtt ttaaagcctc gtgtatagtt catcaagtct aagacatcct gctccgtgtg
    22681 agccatcacc gcaaccttaa caagttttgg atttaggatc gtcaactctg acaagatttc
    22741 catcatgttc tcaggtgttt cttggaaatt atggtaactc aaaacaagat ttgggaagtc
    22801 cagcatttcc tcaaaaacat ccttgtagct atagtactca aaatcaatat agtctggttg
    22861 atagagttgc gcaacttcct tgattagatg gatatactct tctggagaaa ggtcgatttc
    22921 tccaccttcg gagcgagttc gtagcgtgaa aaccaactca cggcctgcga atttttcaaa
    22981 aatggctgga gctacctgca aaatcgcttc tttaggcaga tagtcggcac gccattcaat
    23041 gatgtcggca tccagatacc tcgtggcatc cagagcctga gcctcctcta aacttcttgg
    23101 cattactgaa acgattaatt tcatttacta accttcatac taatcacctt gaggtaatta
    23161 ctactttcat cttttttatt ataggcaaaa tctgctggaa gaccatattt gtttaaaatc
    23221 tggtaacttc ttcctgcaaa acctttatca atttgttctg taaatttctg gcgggaaaca
    23281 ttggcagcat tggtactggc aatgataatc cctcccggat ttaaaatctc aagactctgg
    23341 gaaatcaact tgtgataatc cttggccaca gagaaagttt gttttttatt ccgagcaaag
    23401 ctaggcggat ctaggacaat cacatcgtag gtcaagtctt tgcgtttggc atatttgaaa
    23461 tactcaaaga catccatgac tataaaacga tgctcgtctg tgctgagccc atttgcctga
    23521 aaatgcgctt gagacaattc tcgtgaacgt ttggctagat caacagaagt tgtctggcta
    23581 gctcctccca tggccgcagc tactgaaaaa gccgctgtgt aggaaaacat attgagcaag
    23641 gatttaccca tagtcaagcc gtcaactaaa ctaccgcgaa cctcatgctg gtctaggaaa
    23701 attcctgtca tcaagccatc attcataaag acttgataca ggacaccatt ttctaaaaca
    23761 gtgaaaaagt caggtgcttc ttgaccataa acatgggcag attcatagtc aaaaccctta
    23821 aagcggattt tctcataagc ccctaaaacc tcagggaaaa cctgtctaaa ggcttctgat
    23881 atagtctgac gaatctgata aacataagag ttataccaag aaaagacggc gtagtcgcca
    23941 taaaggtcca ctgtcagacc cccaaagcca tctccctctt gattaaagag acgaaaggca
    24001 gttgtcaaat catcttgata gtaggcgttt ctcttttctt tggcttttct aaacaacgtt
    24061 tcaaagaaag tttgattgaa ggtcaccttg tctttgctga caaaccagcc caagcccttg
    24121 ttttgctgag aaaggtaggc agtcccaaga aagtttcctt cctgaccctg cacctctact
    24181 tcctgatcct taagattgac attctcaaga tcactggctt ctagtaaaac tagcccctta
    24241 gcaagcttct tttcaaccct tttgctgact cttattctat tcataactac cattatatca
    24301 aacttttaga caattctcaa aaaagaaact acccttgctt ttttactctt cttttaaaaa
    24361 atggtatact agacttcctg caaaactagg aagtaaatgt gtaagaatca caataaaaaa
    24421 tgctcttccg tcttggagga gcatttttta ttatcaacga aaatcaaata gcaaactatg
    24481 aaactagcct caggttaact gtgagattat aggtagagag gttgtatcag caatatgtgt
    24541 ctgtcaaatt tagtgacaaa ggtagtagaa gaaagatgaa gaaataaatc agcttcagta
    24601 gatatctgga aaatttgatt ttatagagaa gccttttgtt acaaactcaa tatactatca
    24661 ataaataata ttatagaagc aacaataatt ataatttcac ctatttgcat cattctattt
    24721 cgaactctaa atatatgttc tatcaaaaat acttggatca cacacattat aggaattaac
    24781 gtttttgaaa ttgaaaaata tcccaataaa taaactataa acaacaaaaa tagaactatg
    24841 ttatatttct tattcaaaac attcctccct atatttttga ttaccaatct taatcattta
    24901 caactacatt ctaacaaact ataaaagcgt ttgtcgaatt gaatttatca agcaagcgac
    24961 caaccagctc atcttttttc tatttctgcc aatatgcgtg acaggtaata atgatagcca
    25021 aaaatagcaa gagcaagcag gaggataaga gctcctactc ccaagctgat ggcaaggata
    25081 gtggagagag actgaaccaa gaatatgctc ccaattacaa gggccatcag gattgcacta
    25141 taaataaaca ataaaactat ggcgactatg ccatttgaac gattcaccag gtccgtaatg
    25201 ctactccaat tgattgacag atttttaacg tccttaaagt aatggtggca agaaaggatg
    25261 acactggcaa ggatccatgc cataataagg taaatcatcg aaatgatggg caagcctaga
    25321 tatagagaaa gaccaagtaa agtcagaatt ggtaaaaagg actggacggc atatataatc
    25381 caaaatttca ctttcacata acgagcaaag tcaaagggta aactcttcag aaaatcaaca
    25441 ttttccctct ccaaggacaa ggcaattgaa tgcaggctgg tgatattgtt attgacaact
    25501 gctataaaga gagctataaa aaacaagggt aaccagtatg gaggatgaat gtctggaact
    25561 atctgagaat ctcggatttt ggaaatcaga ccgatcatca tgagataagg aaggaaagca
    25621 cttgtaaaaa gcactgtaac cacgccagta ccctgtccca agagggtgag gtggtagcgt
    25681 aaaaccatgc ggaaaaatcc ctttttagtg gttgaaattc tctccttgct gcgacgttct
    25741 tttttgacct tctcctcact attaagcagg atcacgtcat aaaaacgagg aaggaccttc
    25801 tttttggtca gataaagcag gaagagagtt agtcctatcc aagcgagcag acccactaag
    25861 gcttctgtcg aaaaaggctc cactgctatt ttgtaaaaga tatgaagagg ataaaggaga
    25921 aatggaatgt ctctaacttt gtcaacaata cttccaaaag tcgactgtag aaagaagaca
    25981 aatattaaag gtatgagaac tcctatccca atcatcacat tcgaaaaaat agactgatac
    26041 tttctgaagg ccgtagtttg agccaagaaa tgcactgcca ctaccatcac tagagccaca
    26101 gagacaaata ataaggtcaa ggacagtagc atcaaaggca aacccagcca aagagaagga
    26161 gctagactaa tatagagggc tagaaaataa gctaggattg gtacaattcc agttagagct
    26221 ggcaaaagga cagacagtcc tttagcaatt ataatctctg attctttaaa ggcatagggc
    26281 ctataggagg ccaggtcctt actctcataa aagacattgt aaaatgcagt taaagaagtt
    26341 gaaaaggcaa tcactagtaa aatagcaacc acaaaactaa aataaacagg catttcctca
    26401 aaaggaaaat gaatggctat agtactaaaa aagatgagca tcaagagact ggaaaaaatg
    26461 taagaactta ggactctagc ggaaacattt actttttttc cagtattttt agcttgcttc
    26521 tttcgtaggt tagccagatt agcttcttga gatgaataga ggatattgat atcaactaat
    26581 tttttaatga ccttgagacg catctgaaac ctcctctttt ctaccagcaa ggctaaggta
    26641 gatactttcc aaagactggt ctgggttgtc tcttctcaag tcctctacct taccacaata
    26701 aatcaaatgc ccctttttca aaatagcaat ccgatcacag acttgctcag ctacctctag
    26761 gacatgagtt gaaaacaaaa ctgtcttacc tttttgcgca tgctccttca tcatttgctt
    26821 caaatcaaag gcagcctggg gatccaaacc agtcaagggt tcgtccaaga cccaaatatc
    26881 aagatcagac aagagtgccc cgatgacaaa aactttctga cgcattccat gagaaagggt
    26941 ttcaataacc tgataacgat tttcagcaaa atcaaaaacg ttcaataacc tagctaaact
    27001 agcttccaag tcagagctgc tcaaatcata ggatgaagca atcaattccc aaaattcatt
    27061 ggccgttaaa cgtaaaaata agtcaggcga gtctgctacg tagccaatct ttcgtttgat
    27121 cgccaagcga ttttccgata aatcctgacc atctaccaaa atacgaccac tgctgggtga
    27181 aatgatactg actagggatt ttatggtggt cgattttcca gccccattat gaccaatcaa
    27241 gcccataatc tctccatttt caatctgcaa attgagatta ctcaaggcct ctttatcacc
    27301 atacaactta ctaacatttt gaaattcaat catgggacaa ctcctatctt tatctgtatt
    27361 atacatcgct atactagcac tttgatacaa aaaaatcaat actttatttt aagtagttaa
    27421 aatagtttcc ttctatctta cgcaaacgtt tgcgctaata gatactttat gatagaataa
    27481 agaacaagat tgacaagtaa gaggaaacat catgcaaaat caaacactca tgcaatactt
    27541 tgaatggtat ctgccccacg acggtcaaca ctggacgcgt ctggctgaaa atgctccaca
    27601 cctagctcat ctggggatca gtcacgtctg gatgccacca gcttttaagg caaccaatga
    27661 aaaagatgta ggttatgggg tctatgactt atttgaccta ggagagttca accaaaaagg
    27721 gactgtccgc accaagtatg gtttcaaaga agactatctt caagccattc aagcccttaa
    27781 agcgcaggga attcaaccaa tagccgatgt agttctcaac cacaaggctg ctgccgatca
    27841 cagggaagcc tttcaggtta ttgaagtgga tcctgtagac cgtacagttg aacttggaga
    27901 acccttcacc atcaatggct ggactagttt taccttcgat ggtcgccaag atacctataa
    27961 tggcttccac tggcattggt accacttcac cggtacagac tacgatgcca aacgcagtaa
    28021 atctgggatt tatctgatcc aaggggacaa caagggctgg gctaacgagg aattggtcga
    28081 taacgaaaac ggaaactacg actacctcat gtatgccgac ctagacttta aacatcctga
    28141 agtcatccaa aacatctatg actgggctga ttggttcatg gaaacgactg gtgtagctgg
    28201 tttccgtttg gatgccgtta agcatattga ctctttcttt atgcgcaact tcatccgcga
    28261 tatgaaggaa aaatacggtg acgatttcta tgtttttggt gaattttgga acccagacaa
    28321 ggaagccaat ctggactatc tcgaaaaaac ggaagaacac tttgaccttg tcgatgttcg
    28381 tctccaccag aatctctttg aagccagtca agctggcgca aactatgacc ttcgtggcat
    28441 ttttacagat agcctggttg aactcaagcc tgacaaggct gtgacttttg tcgacaacca
    28501 cgatacccaa cgaggacaag cccttgagtc taccgttgaa gaatggttca agccagcagc
    28561 ctatgccctc attttgttac gccaagacgg ccttccatgt gtcttttacg gagactacta
    28621 tgggatttca ggccagtatg ctcaagaaga tttcaaagaa atccttgacc gcctcctagc
    28681 catccgaaaa gacttggcct atggagaaca aaatgactac tttgaccatg ctaactgtat
    28741 cggttgggta cgttcaggtg ctgaaaatca atccccaatc gcagtcctta tctcaaatga
    28801 ccaagaaaac agcaagtcaa tgtttgtcgg tcaagaatgg actaatcaaa cctttgtaga
    28861 tttacttggt aaccaccaag gtcaagttac aattgatgag gaaggttatg gacaattccc
    28921 tgtctcagct agatccgtaa gtgtctgggc agtcaatacc atctaatagc tcataataac
    28981 caagctaggt ccaagcggat ttggcttttt tgtattcaca aaaagaccta cccaaatgga
    29041 tagatcttta cttgattaca atttacctgc tactgcatcc aacaattctt ggatcttagc
    29101 ttggttgctt cctcctgcca tggccatgtc tggtttacca ccaccacgtc catcgatgat
    29161 tggtgctaat tctttgacaa ggtttcctgc atgaaggtct tttgtcttgc ttgctacaag
    29221 gacattgact ttgtcaccga tagcggcaac taggacaaga agatcagagt agtctttttg
    29281 tttccagtta tctgcaaaag tacgaagggc accggcatcg gatacagaca cttgactagc
    29341 aatgtaacga tgaccgttga cttccttagc atctttgaag atatcgcctg cggctgcagc
    29401 tgcggctttt tctttcaact cagcattttc tttttgaagt tgacgaagtt gttcttgaag
    29461 tccttctacc ttgtgaggta cttccttgac ttgaggtgct ttcaaggttg ctgcgacagc
    29521 tttaagagca tcctcttgtt cacgataggc ttcaaaggct tccttaccag tcactgccaa
    29581 gatacggcga gttcctgaac cgattccttc ttctttgaca attttgaaga gaccaatctc
    29641 agaagtgttg ccaacatgag taccaccaca aagttcaata gagtagtcac cgatagtcac
    29701 gacacgaact tccttgccgt atttctcacc aaagagggcc atagctccca tttctttagc
    29761 agtgtcaata tctgtttcaa ctgtcttcac ttcaagtgct tcccaaattt tctcgttaac
    29821 ttgctgttca atcgcacgaa gttcctcagc agttactgct tggaagtggg taaagtcaaa
    29881 gcgaaggaat tcaacttcgt taagagatcc tgcctgtgtt gcgtggtttc caaggatatt
    29941 gtgaagggca gcgtgaagca aatgagtcgc agtgtggttt ttcatgacac ggtgacggcg
    30001 attgctatca attgccaagg tatattcttg gttcaaggca agcggtgcaa ggacttcaac
    30061 tgtatgaagg gcttgaccat ttggggcttt ctgaacattg gtcacagtag ccacaatctt
    30121 acctgactca tccaagattt gtccgtagtc agctacctgt ccacccattt cagcataaaa
    30181 tgacgtttcc gcaaagataa gagaggcagt tccttctgaa acagctccta cttctgcatt
    30241 gtcagcaacg atagctacca atttagaaga caattggcta gtattgtagt tgaagacact
    30301 ttctacagtg atgttttgaa gagtttcatt ttgcataccc attgagccac ccttgacagc
    30361 tgacgcacgc gcgcgttctt gctgttcttt catggctgct tcaaaacctt cacggtctac
    30421 agtcatacca gcttcttcag caatttcttc agtcaattca actgggaatc cgtatgtatc
    30481 atagagttta aagacatctt gaccagcaat gacagattga cctttttctt tcaagtctgc
    30541 cacaatgcct tgggcaaagt gttgacctga gtgaagggta cgggcaaatg attcttcttc
    30601 gctcttaacg attttctcaa taaagtcacg tttctcaagc acttctgggt agtagctttc
    30661 catgattttt ccaacagttg gaacaagttt gtaaaggaaa ggctcgttga tacccaattt
    30721 ttgaccatgc atagaagcac gacggagaag acgacgaaga acataaccac gaccttcatt
    30781 tcctggaagg gcaccatcac cgatagcaaa tgaaagagaa cgaatgtggt ctgcgataac
    30841 cttgaagctc atgttgtcgc catcttggtc ataaacctta ccagacaatt tctcgacttc
    30901 acggataatc ggcatgaaga ggtccgtttc aaagttggtc ttagcccctt ggataacagc
    30961 caccaaacgc tccaaaccag cgcccgtatc aatgttctta tgtggcaatt ccttgtattc
    31021 gctacgagga acagcagggt ctgcgttaaa ttgtgacaaa acgatgttcc agatttcaat
    31081 ataacggtcg ttttcaatat cttctgcaag caggcgaaga ccgatatttt ctgggtcaaa
    31141 ggcttcccca cggtcaaaga agatttctgt atctggtcca gaaggtcccg caccgatttc
    31201 ccagaagttg tcctcaattg gaatcaagtg acttgaatcc actcccactt caatccagcg
    31261 gttgtaagaa tctttatcgt ctggatagta ggtcatgtaa agtttttcag cagggaaatc
    31321 aaaccattca gggcttgtca aaagctcata agcccaagtg atagcttcgt cacggaagta
    31381 atccccgata gagaagttcc ccagcatttc aaacatggta tggtgacgcg cagtcttccc
    31441 tacgttttcg atgtcgttgg tacggatagc cttttgggca ttggtaatac gtggattttc
    31501 agggataatg gtcccgtcaa agtatttctt aagggttgct accccagagt tgatccacaa
    31561 aagagttggg tcatttacag gaaccaaact tactgatggt tctactgagt gagctttggt
    31621 cgcccagaaa tcaagccaca tttggcgtac ttgtgcacta gatagttgtt tcatattgtc
    31681 tccttattta cttgtttaat gtgattggct ttccagcatt tccacatagt caatcgcgac
    31741 acagagggaa atgactaggt ctgcataagc gtcctcaaga accgttacgg tataggtaga
    31801 ggtcagatgg aagagttcct tcttaatttc cgcaatcagc tgatcgcgat catccagcaa
    31861 tttgaaattc aaatcccaga tattgccctc gatacgaaga cctagattat caaactcata
    31921 cttatctcgc cagaaggtca acttcttacg aatgacaaaa ctcgagccat cccgaagctg
    31981 aatctcaaaa cgaggaagca aggtcaagat ttctttacta atctcactga cttgttcacc
    32041 agccgcatca tagatggtaa aggttttagg aatcttaaaa aatgatccct ccacctgata
    32101 ggcaatttct cccctgtcat ccttgatagc gaagcgttcg cctccaagac gaaacttttg
    32161 tttgacaaga aatgttttca tcaacacctc caaaaatcaa aagacaagct catatcacga
    32221 agggcgaaaa accgcggtac caccttcatt caatgaactt gtcattctct tgttcttatg
    32281 caattgtatg attgagtagc atgacttcct agcttagatg gctcgcagca ccgccatttc
    32341 tctggactaa gacaagtgaa aatcaattct caactttctt attataacgt ttttttaagc
    32401 ttgcgtcaac tggaaatgat ctccgttgaa ttagaccaat tccctacatc tctgattact
    32461 ttttcaggat atattttttc ttactgccgt ttttcttttt atcccaaatt ttcatattac
    32521 taaacacagc tactagaata tttccaaata taaaggtgcc tatcacccaa tatatggact
    32581 cagttgttag gtattgtcga tccaagccat cctttaaatg ggatagtata acagtttggt
    32641 taacaatcat aaaggttggc cagaaacttt ttttgaaaaa agtagacatt ttcattattt
    32701 gttgccgctt tctgtaaggt taatactcaa taaaaatcaa aaagcaaact aggaagctag
    32761 cctcaagctg tacttgagta cggcaaggca acgctgacgt ggtttgaaga atataggctt
    32821 agtatactac taggcaagca aataagcaac tagaatagaa aaagataggg ttctaaaaac
    32881 tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac gtttatctcc
    32941 tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt ccatttatgg
    33001 tcaaatttct cataaacttc taggtgtttc atggtttcaa catctggata gaaggcctta
    33061 tcttcctttg tttcctctgg gagcaattcc ttcgctggta ggtttggtgt tgaatagccg
    33121 acatactccg cattttggaa atcgttttca ggtttcaaca taaagttgat aaaggcatag
    33181 gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca aagattgctg
    33241 gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg gctggcttca
    33301 ccagagaagg tcacgccgat tgcaacatta ttctgaatca tgtagccctt catctcgtcc
    33361 gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt ctcttccaac
    33421 tgctgcggat ccttggagtt gaggctgtag ccgagggaat tgagtcctag tcccagcacc
    33481 tcacgcgccc catcaaaaag catgatagaa ttcttatact ccagcttcca aaggtcatcc
    33541 caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa ggttccccag
    33601 aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa ctctggtccg
    33661 atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc ttcgtccttc
    33721 atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc accctgcttt
    33781 atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg aattcctgtt
    33841 tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt atagataacc
    33901 aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat tccccacaag
    33961 acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat gcttgctcct
    34021 ccttctcacg agagataaag taataaccta caactaggat aatactaaag agaaagacta
    34081 gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag taaatctcga
    34141 ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag tcatctaacg
    34201 aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa ggaagcatga
    34261 tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga atcatgtcgc
    34321 cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg gagaaggcca
    34381 cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta aagagaatca
    34441 agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg agtgatagaa
    34501 aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa gtcccgataa
    34561 tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa atcagcatga
    34621 gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta aagctattca
    34681 tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg tagaggacca
    34741 gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc tttccttagt
    34801 cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg aacccatacc
    34861 atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga taacgcggtt
    34921 cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga ccgactgaac
    34981 cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg tctcccactt
    35041 agtggcacca aggtcataac tagcattgat gagattatta tccatatcgt ctaagacatt
    35101 gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga taaaggaaaa
    35161 atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt ggttaataga
    35221 gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat tgagccaggt
    35281 aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca aaaagagggc
    35341 tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa gcactgagtt
    35401 gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat aattttctaa
    35461 actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca agggtgccaa
    35521 tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc ttgttttctt
    35581 catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg atttccacgt
    35641 attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg atgtggatgt
    35701 cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg gttgagtgga
    35761 tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact ccacggaaga
    35821 gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg cgcaagtcct
    35881 ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca accgcttcaa
    35941 agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc aagatgtttg
    36001 actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg tccacagggg
    36061 ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc atggcaagag
    36121 cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt tgtaattcac
    36181 gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa ggctcgtcca
    36241 acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc tgacgttgtc
    36301 ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc atcttgagaa
    36361 cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga agtggaaagg
    36421 caacattttc aaacacattc atatgtggga acaaggcata ggattggaag acggtatgta
    36481 cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg atatctcctg
    36541 tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc gaaccagatg
    36601 cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct ttgagaacct
    36661 tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt ggttttttca
    36721 attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc aggtccccac
    36781 tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag gctttcaccc
    36841 cctttccatg acatagcagc agcttttcaa atacagcttc ctacttgctt tcacccaaga
    36901 tccggacttc tctttcaagc gtaatacctg agtgttcctt gactttttcg ataaccgatt
    36961 ggatcaagtc ctcgtagtct ttggccgttc catctgcgac attgatcata aatcctgcat
    37021 gcttttctga cacttctacg ccaccgatac gatagccttt caagccagct tctgaaatta
    37081 actgacctgc aaaatgcccg actggacgct taaagaccga gccacaagat gggtattcca
    37141 aaggttgctt gagttcacgt aggtgcgtca agcggtccat ttcctgcttg ataacctgat
    37201 gggttcctgg ggctagggca aatttaactg acaagacaac tgcaccagac tcctgaatag
    37261 ctgaatggcg gtaaccaaaa gccaagtctt tagcagacag ggtttcgatt tctccatcct
    37321 tggtcaagac cttacaagac tgcaatatgt gagcaatctc gccaccatag gcacccgcat
    37381 tcataaagac agcaccgcca acgcttcctg gaataccaca agcaaactca aagccagtca
    37441 aactatgacg gagggcaatg cgagttgttt caatcaagtt agccccagct tctgcttcaa
    37501 tggtatagcc atcaacagaa acgttattga gcttgtcaca caagatgaca aatccacgaa
    37561 tcccaccatc acgaacgatg atattgcttg cattgccaag aaccatccaa gggatatttt
    37621 cttggttggc aaatttcaca acgcgagcca actcaaaacg atttcgtgga aagaccaaat
    37681 aatcagcctc tccacctact tttgtataac tatagctatg caagggttcc ttaaaacgga
    37741 tatcaattcc ttctaagatt tcaagcattt tttctcttac agacatgtca ctcttccttt
    37801 tacaaaattc attccattat accattttta gagacatttg acgaccataa aaataccttg
    37861 tttggatttt gcataagaaa aagaggttcc ccccttttta tgatttttta caaaagattt
    37921 ccttggttcc ataggcaacc agaacgagct ccagtgctag aatcacttca accaagactg
    37981 gatttgtcaa ccagcctact tggaaaagag atggtgccag atcaaagaag gcatgcaagc
    38041 cataggctgc taggagataa atccatttct tctggcgaac agcttggtaa acccaaactg
    38101 tcaaaagtaa ttggaaacca agcgccaaga ttcgctcaaa accaagcaaa taaatctgcc
    38161 agaccgaaag tgactgaatg gtttttaaca tattttcaga cagtaattgc ataacctgtg
    38221 gattctgagt ttgaactgcc gaaagaacga tgtaaagatt gagtaaacta gtaaggccta
    38281 gaaaaatcaa ctccaagcca ccatgcccta gaccataggc caaggcatct gccttttcca
    38341 aacttctctt tttctccaac catttgaaga aaacaagacg agccgtttcc tcaaaaaatg
    38401 ctgccatggc taggccatag ataatataga taagcggatg atcttgcaag agggcaatac
    38461 taccgtcttt ttgaggatgc aaaatcaaga tatgcaccag tttttccaaa atctgcgaag
    38521 agacaaagaa agcgactgca cccaagccca agacagctag attaatctgg tatttctttt
    38581 tggcaaacca aatgcttcct atcagaaaag ctagcaacag caacatggta ataatgatat
    38641 gaatggtcat tttcttctcc tattctgcct tttcaatatc ttttttcatc tcgtcaacat
    38701 tgaacttagc aaacaagtat tgacggtctt ggactgggaa acgttggtcc aactggtcaa
    38761 ctgctcccac ctcgataatg ccttccttga tgacaaaatc catgacatgt ccaccgaagg
    38821 tcaaatcatc tgatatgaag tgcagatggt agcctgccac actgacccca tggaaaatct
    38881 caggcgtcca gaaaccaaca atagtccccg caacattgtc acgactatat tccggttgat
    38941 gggttgcgat atcagcaaac ttggtatcgg gtgttgactt aggaatcata cgcacatgca
    39001 tatgtgaaaa ttccccccga atcttgatag agcggaaaag attttcccca tcataataag
    39061 actcaattcg ttctttcaat tccttgtctg tcatctcaaa gcgctggcgg aaaatgacct
    39121 ctgcctgatg cggtaccact gcagcgtaag gaataagggc atctggtgac acttccacaa
    39181 tttctggctg gtctcctgac tctttggcct gataagcctt gccatccaag acaatcaatt
    39241 ccccatcaat ggaatccaag gttcccaaac caaggtcacc atgttctagc aattctccta
    39301 ctgtcatagt accaccataa aggccagcca tcaaggctcc aagagtattg tattgaaata
    39361 atttcactgg ttcctgcacg ttcttatcca ttcactttct tgtctgttat tctataaatc
    39421 ttattcctaa gtataccaca tttgccccta gatgtgaacg agagaaacgc tctagacatt
    39481 gccaagaagg aaaaaaaagg gtacaatgta acaaaatcaa gggaggtctg gaatgaagaa
    39541 acaaagcaag tacaaagagg tcgtttccta tctgaaaaat ggtatcgagt ctggacgatt
    39601 tccgacgggt agtcgcctgc cttctatccg tcaactgagc cttgactttc actgcagcaa
    39661 ggacaccatt caacgagccc tgctggaatt acggcacgaa caatacctct atgccaagcc
    39721 tcagagtggc tactatgtat tagaacaagg gcaacatcaa gacctagaaa tcgaggttac
    39781 cgacgaacat gccagtgcct atgacgattt ccgactctgt gtcaatgaaa ccttgattgg
    39841 ccgagaaaac tacctcttca actactatga caatcaagaa ggattagaag acctaagaca
    39901 atccattcac aaactcctct ttgaccaagc tctctactgc aaggctaacc aactagtact
    39961 gacttctgga acccaacaag ccttgtttat cctctctcaa atatcctttc ctagccaagc
    40021 caaggaaatc ttggtggaac agccaaccta ccatcggatg aatcgcctct tgattgcaca
    40081 ggggctggac tatcaaacga ttgaacgagg cattgatggg attgacttgg aggagctgga
    40141 aggccacttc aaaacaggaa aaattaagtt tttctacacc attcctcgat ttcactatcc
    40201 cctaggccat tcctattctg agcaggacaa acgagctatt cttgacttag cagccaaata
    40261 tagtgtttat atcgtcgaag acgactatct gggggatttg gactctaaaa agggccagac
    40321 cttccactat ctagatacag aggaacgcgt catttatatc aaatccttct caaccagcct
    40381 ctttccagcc ttgcggataa cagcactcat tcttccaaat actatcaaag aagccttcgt
    40441 ggcctacaaa aatatcctag actacgacag caacctcatc atgcaaaagg ccctgtcact
    40501 ctatattgac agtcaattgt ttgaaaaaaa tcgtttggct cgcttgacca atcatgaatc
    40561 ttaccaaaaa caaatcgagg aaaggataac taaaacacct tgtccccttc ctcattatcc
    40621 cctacacgat ggtttattgc tagacctgag acagtatcct aaaatcgcca gtctcaaaca
    40681 cagtcaactg ggcttggact tctttgaaga ggcctattta agcacctgtc cttatcaatt
    40741 tgccaaggtg tccctagaca atctggaaaa tgttttaaac tatttaaaag cagaattgga
    40801 atgacatcca actctgcttt ttcttattct tcaacttcag ttaaacttgc tgctttttca
    40861 agatagcttt ggtaagttcc ttcatcctta agtttttgga tgaccttgtc taccacttct
    40921 ttcaaatcat cactattttt tctaagagca acggcattgg cgtcgccgtc cttcatcttc
    40981 aagctgacag ttgcgacagc taagccagcg tttttagcag cataactaag tgcaacaggc
    41041 tcatccatat gaacagcatc tatttttcca gcctgcaatt cattgactgc ttcacccata
    41101 ttagttaggg aagttaattg agcttttggc aattgttcct tgaccattga ttctggaaca
    41161 gtcccttttt gggctgcaat attagcactt tctaggctag ttaaatcctt gtatttttcc
    41221 acatcagcct tacgaaccaa gaaactaatc ttgttttcat agtatgggat tgaaaaatca
    41281 aagacttctt ttctctcgtc agtagcacta attcctgcaa ctgctaggtc agccttacca
    41341 gtttgaagac tggtcaaaac attgtcaaaa ctcatgctta agatttccaa cttaacccca
    41401 agttcatcag cgatagcctg agccatgtcg atgtctgcac cgactacctg gttctttcca
    41461 tcaaccaatg attgaaattc aaagggtgca tagtcaggac tggttgccac aactaatttc
    41521 cctttttgtt tgatagcatc cacagcagac tgagaaccat tagaacctga ctggcaagct
    41581 actaagaaga aacttgcaag aaaattacat aaaacaaata tccatttttt tgatttcata
    41641 aataaacaac ctctctgtta attttgtata attataacga tatccaagtt acttgtcaag
    41701 tgttttttaa atttttatct caaaaatatt ttttcgttca aaaaaaggag ccatcagttg
    41761 atttcaagct cctttttata cagaattaaa ctattttata gttcgacaat cttacctgtt
    41821 tcaaagtaga caacccattc acagatattt ttagcatagt caccgatacg ctccaagtag
    41881 gaaataactt ggaaataatc acgacccgta acaatggctt ctggattttt cttaatctct
    41941 tcagtcgcaa ggtcacggat agtttcaaaa tagtggttaa tttgctcatc catggaggcc
    42001 acccggtatg cgtcgtcaac agaaccatta agataaagat caagtgctgc ttcaacaacg
    42061 cttttaactt cacgtcccat ttttttaatt tcttcctcta cagctggaat gcgctcttcc
    42121 cccttcatac ggatggttgc ctgggcaatg gctacagcgt gatcccccat acgctccaca
    42181 tctgatacag ccttaaggac agtcaagact gtacgcaaat cttgagagac tggttgttgg
    42241 agtgcgatca tttcaaatga tttcttttcc agtttcactt cgtattcatt tacttctgca
    42301 tcatcttcga tgacctcttt tgccaggtca cggtcatgcg tgacaaaagc acgtaccgta
    42361 cgattgattt gtgagagcac ttcttgtccc atagcgtaga actggttatg taatttctct
    42421 aaatcttctt caaattgaga tcgtaacatc tttcatctcc ttatccaaat tttcctgtaa
    42481 tatagtcttc cgtttccttg tgttggggat caaggaacat ctgcttggta tcattaaatt
    42541 caatcaaatc tccatctagg aaaaatcctg tcttatcaga gatacgtgaa gcttgctgca
    42601 tggaacgggt taccagaagc atggtgtact tgtcttttag accatacaag gtttcctcaa
    42661 ttttaccagc tgaaatcgga tccaaagccg aagttggctc atccaagagg atgattttag
    42721 gactagttgc caagacacgg gccacgcaga cacgctgctg ttgaccacct gacaatccaa
    42781 tagctgaatc atatagacga tccttgacct catcccagat agaggcacct tgcaaggctt
    42841 tttctacggc ttcatccaga acctgcttat ccttaattcc attgatacga agcccgtaga
    42901 caacattctc atagatagtc atagggaaag gattaggttg ttggaaaacc attccgattt
    42961 ccttacgtaa ttcaaccgta tctgtacgcg gactgtagat gttgtggcca ttgtacacca
    43021 cggatccagt tgtggtcacc tctggattga gatctcccat gcggttgaga gacttgagga
    43081 gggttgactt ccctgatcca gatggaccaa tcaaggctgt aatttcctta ggttggaaag
    43141 atagggaaac actattcaaa gccttctttt tattataata aacggacagg tctgatacct
    43201 gtaaaatcgc atctgtcata cggtttcctt tctaaccaaa gtgaccagat acatagtcat
    43261 tggtggactg tagcttggca ttttggaaaa tagttgcagt cttgtcatac tcaatcaaat
    43321 cacccaagta aaagaagcct gtatagtcac ttgcacgagc agcctgctgc atattatgcg
    43381 ttacaatgat gatggtaaag tttttcttga gctcaaacat ggtctcttct agttgcatgg
    43441 tcgcaatcgg atccaaggct gaggctggct catccattaa gaggatatct ggcttaacag
    43501 agatggcacg agcgatacag agacgttgtt gctgaccacc tgataaggtc aaggctgact
    43561 tgtggagatc gtctttaacc tgatcccaga gggcagcctg acgaagggag gtttctacga
    43621 tttcatctag gacttgctta tccttaactc cagcacgttc atgcgcaaag gtaatattac
    43681 ggtaaattga cttagcaaat ggattggggc gttgaaaaac cattccaatg tgtttacgca
    43741 tttcataaac gttgatttct ggacggttga catcaattcc acgatagaga atctgcccag
    43801 ttactttagc aatatcaata gtatcattca tgcgattgag actgcgtaag taggtagatt
    43861 tccccgatcc cgacgggcca atcaaagctg taattttatt tctttcaaat tgcatatcaa
    43921 tccccttaat ggattcattt ttaccatagt aaacatggac atccttagta gaaagggcta
    43981 ctttttcttc aggaaaggta aggatatgct tctcatccca gttatatgtt gacatggctt
    44041 ctcctttagg cagcggttaa tttcttgtgt agatagcttc cgaacttacg agctccaaag
    44101 ttaaaaatca ggataaagat caggagcaca gcggcagaac ctgctgatac aattgttcca
    44161 tctggaatag tgccttcact attgactttc cagatatgga cagccaaggt ttctgcttga
    44221 cggaagatag agatggggct agtcacactg aggatattcc agttagacca gtcaagagct
    44281 ggcgccgatt gccctgctgt atagatcaga gctgcagctt cgccaaagat acgaccagat
    44341 gccaagacga cacccgttac aatacctgga agcgcttctg gaataacaac atgaaccact
    44401 gtctcccagc gagaaatccc aagagccaga ccagcctcac gttgggtatg gtgaacgtgt
    44461 ttcaaactat cttctacatt acgcgtcatc tgaggcaagt taaagactgt caaggccaag
    44521 gcacctgaaa tgattgaaaa tccatactca aactggacta caaagatcaa gtaaccaaag
    44581 agacccacca ccactgatgg taaagaggac aagatttcaa tacaagtccg cacaaagttg
    44641 gtaacaggac cttttttagc atattcagcc aagtaaatcc cagctcccat agaaagaggt
    44701 acagaaataa tcaaggtaat gaccaatagg aaaaaggaat tgtaaagctg aatgccaatc
    44761 ccaccacctg cttgaaaagc agaagacctt ccagtcaaga aagaccaaga gatatggggc
    44821 aagccccgaa ccaagatata gagaatcaag gaagccaaga ttgtcacaat gatgctagca
    44881 atcgtataga ggacagctgt tgcaagttta tctaattttt tagcgcgcat aatttttctt
    44941 ccctctttct ttcgtaatca atttaatcac actgttaaaa actaaactca tcaagagcag
    45001 taccaaggcc agtgaccaga gaacattatt atttacagtt cccatgacag tgttcccaat
    45061 tcccatagtt aatatagaag ttaaagttgc agctggtgtg gtcaaggaag ttgggataac
    45121 agctgagttt ccgacaacca tctggatagc taaagcctca ccaaaggcac gcgccatccc
    45181 aaagaccact gcagtgaaaa taccagaacg ggccgccttc aagattacac gccagatagt
    45241 ctgccagcga gtggctccca tagcgaaact ggcctcacga taataacgag gaaccgcacg
    45301 caagctatcc gttgtcataa aggttacggt cggcaaaatc atgacaaaga ggacggaaat
    45361 ccctgacaaa atcccaaaac cagtcccacc aaagacactg cgaacaaagg gaacgacgac
    45421 ttgcaagcca ataaatccgt acactactga aggaatccca accaggagtt caatagctgg
    45481 ttgtaaaatc ttcgcccctt ttggtgatac ttcggtcata aaaactgctg caccaatagc
    45541 aaagggtgtt gcgataaggg ctgagagaat ggtaacgata aaggaaccca aaatcatagg
    45601 aagggcacca aattctttac tagaaggatt ccaagttcct cccaaaagaa agtcaaagat
    45661 attcacacca ttgacaaaga aggtcgacaa gcctttttgc gctacgaaaa ccaaaatcat
    45721 ggccacaagg atgactatca aagaaagaca ggcaaaggtc aaaccttttc ctaatttctc
    45781 cagacgagaa ttctttgatg gaagcaacat tttcttagct aattcttctt gattcattat
    45841 tgtctccctt ccaacactgt cacagttccg gcagcatctt tttcaacctt catttcctta
    45901 atcggaatat acttcaatcc tttgacaatc ccttcttggg tctcatccga gagaacaaaa
    45961 ttgagaaatt ctgcagctaa ctcattgggc tgccccaatg tatacatatg ctcataagac
    46021 cacaagggcc aattattgct acttatattt tctggactta agtcatagcc attcaacttc
    46081 atgcttttga ccgaatcatc tatataggta agagataaat aagagatagc tcctggactt
    46141 tttgatacga ttgattttac cgctccattt gaatcctgct cctgactttg catggcagac
    46201 tgaccttcca taatgacagt atcaaaggta gcacgagagc cagagccggc tgcccgattg
    46261 ataacagaga tgggtaagtc cttaccacca acctctttcc aattggttac ctcacctatg
    46321 aagatttgac gaagttgctc tgtcgttagg ttatcaacat caacctcctt attgacaatc
    46381 agagccaagc cagctaccgc gaccttgtgg tcaacaagag cagaagcatc aattccgtct
    46441 ttttcctcag caaatacatc tgagtttcct atatcaactg ccccagactg aacctgggac
    46501 aagcctgtac cagaacctcc cccttggaca ttgaccgttt ttccaacatg gatcgtgcca
    46561 aattcatctg ccgctacttc aaccaagggt tgcaaggcag ttgagccaac agccgttatg
    46621 gattctccac gatcaatcca gctagcacag cctactaaac aagccgtcag ccaaaaagcg
    46681 ataagagaca gagcaagctt ttttcttttt ttcactgttt ttctcctcga aaataattat
    46741 gaatactgtg aattttttaa gtagttcttt atgagttgac gcatgaattc ttaccaaatt
    46801 tctgcgcaat tgattattta tataatatag gctatattac tctttcctaa cctccttttt
    46861 tcatatgtgg ataaaatctc ttgtctatcc cttcccccat tgtcacccat tatagtcatt
    46921 tcgtgtctct ttttcccctt tttaatgcaa gggaaattac tctccttaga tgataatcta
    46981 aaagctagaa aggtatctca aatctctcta ctctcccaga ctagtttaca actaaaagga
    47041 aaagattcta ttttatgaga aatctagttt acaagcggta agaacgctaa taactaaact
    47101 tcttgtactc tttgaaaatc tcttcaaagc agtgttttga gctatctatg gctagcttcc
    47161 tagtttgctc tttgattttc atcgagtagt aaaactacat gtgatggcaa tcaagatatc
    47221 aagaatcatc ctactaaaaa aatccatact ttcactataa catagaataa gatatttgac
    47281 tagcattttc atttgaatct gaggcctttt ggaaaataat ttttcaaaac atttccagta
    47341 acctttgcaa agcccaagcc attgccttta accaaaactt ggtaccaacc atttggcaga
    47401 ctttctgcca gctgaacggt ttctccagcc gcatacttga caaactcttc ttggccaatt
    47461 tcaaccgact gttcgacctg actcggtttc aaggctaaac caagagcgaa actgggctca
    47521 aagcgtttct tcttaaaagt acccagatgc agtccattgc gagcaatctt gagcttccct
    47581 aaatctggca aaagttctgg caagagataa agctggtctc caaaaatctg caagataccc
    47641 ggtagattga ccttcaaatg gttttgggca aattcctgcc acaaggcaac ttgttcacgg
    47701 ctgaggttac tcttacttgc cttaaattta ggagctggat tgttaccctt aaactgtaga
    47761 tgggcaacaa actgaccctc tcccttaaac tgatgagggt acatccgagc cgtttctggc
    47821 aggtcaatac cagctaccat tccattgata tgctctactg gcaacaagtc aaaatcatac
    47881 tcttccagca accaattgac aatctcttcg ttttcctcgg gtgcccaggt acaggtcgaa
    47941 taaaccagac gaccaccttc agctaacatg gtcactgcat cctccagaat ttctctttgc
    48001 aagctagcac attgactcgg ataatctaag ctccaatagt ccatagcatc aggttgctta
    48061 cgaaacattc cttcaccaga gcaaggggca tcaagaacga ttaagtcaaa atagccttta
    48121 aagaccttga ccaagcggtc ggcagattca ttggtcacca cgacatttgt cgctccaaaa
    48181 cgctccatgt tttcaaccaa aatcttagcc cgtttgcttg aaatttcatt ggaaacaagt
    48241 agcccctccc ctgctagata ggctgccagt tgagttgatt tgccccccgg tgcagcagcc
    48301 aagtccaaga ccttcatacc aggactgggt tgggctactt gagccaccat ttgagcagca
    48361 ggttcttgcg aataaactaa acctgtagca tgctcaggcg atttccctga aaccttccca
    48421 tagtggcccc aaggggtttg agtaatggca tcagaaaagg aaagttgctc ttcttttaag
    48481 ggattgaccc gaaaggccga aaccgcttcc tcctcaaaag aggcaagaaa atctcttgcc
    48541 tcatctccta gtatttcttt atatttttca acaaatcctt ctggaaattt catttaagtt
    48601 cttttccttt cgtaaatata ggactgaatt tcctcctgca tctcaagagg caccatcatg
    48661 accggctgtc tggtttgaaa atcaggagct tcaccaaaaa gggtcacaac ccgatagccc
    48721 agactttccc ctaaaatact agctgcggca taatcccatg gttgcagata ggtgagatag
    48781 gtcaacaaac gccctgacaa aatcttggca aaactaatgg ccgcacttcc atagacacga
    48841 acaccaagaa ccgctcggct caaatcagcc agcccccatt cattggtttc cagcatacca
    48901 ctattccctg caatgagaaa atctccaagt ggtttagttt taaaagaagc taggggccta
    48961 tcatttagac aaactggaaa ttccccacca ccgtggtaac aatccccttt gaccacatca
    49021 taaatcagac caaactgtcc ctgaccattt tcaaaataag ccatcataac agcaaaatct
    49081 tcctgctggg ctacaaaatt attggtacca tcaatgggat caatgaccca aaccttgccc
    49141 tcttgaaccg aggctcgcag acaaccttct tcagcacaaa tcttatcctc aggataacgg
    49201 gacaaaatct caccaaccaa gagttcctga acttctttgt ccagtctggt caccaaatct
    49261 gttggagagg acttggtttc aacacgcaag tcttcctgca tatggtcaag aatgtactga
    49321 cctgctttct taacaagctc tttagcaaat tcaaatttac tttccaagag aaatctttcc
    49381 ttcccctttt tctttggcag cctgaactgc tcggtaaagt gaatagccac taaccgtttc
    49441 aaattctcgt cccaaacgtt tctcttcgct cttgcttggc acgaccgctt tgaatccctt
    49501 ataggagtcc agtaactttt tagcctctac tttgccttca taggcagctt caacatcatt
    49561 aaaaaaagaa agcactgaag caagttcttc agtgctccac gacaaatcta gtgggtaact
    49621 atactgtttg ttcattaact aataccagct ctcattcttg cttcttttag ttcttgctta
    49681 cgataactac gagggagaaa agcacgaatc tcatcttcat taaaaccgat ttgcatacgc
    49741 ttggcatcaa taataattgg acgacgcaaa agactaggat actgctcaat caaatgaagc
    49801 aattccgata ccgaaatact ctctacatca atattcaatt tttgaaaaat ttttgaacga
    49861 gttgaaatga tgtcatcagt accattttcg gtcaaggaaa ggatgtgttg caattctttt
    49921 cttgttaaag gactggtcat aatattgtgt tccacaaagg gaaccttatg tttttctaac
    49981 caggccttag ccttacgaca tgatgtacag ctcggtgata gaaatagtgt aatcatgctt
    50041 ttctcttctt atctatactt tgctacttct attatacaaa aaaataaagc gcttgactag
    50101 ggatttttag aaaaaaaagc ctatttttca agaaaaatag gctttttgcg aacgattgac
    50161 acaattggat ttggttaatt cactcttaac gatggtttta aacgatatat atttttatat
    50221 atgcaaatta aaaacatctt tcatttcatt tcctacgact tttcagacac agatagccaa
    50281 agaagctttc atagagggca aaaaagagga ggaaggcatg aagaaagaag gtctctggca
    50341 aaatcataat aacaggatcc ttggctggat caaaaagcca ggtatcatct cccacaaaga
    50401 gaatttgatg gaaaagagta aagaattggt caaaaccaat caaaactccc ccaagtccaa
    50461 tcatcacagg taagactact agagtcagga gactttttcg ataaagagac aaaaagtcct
    50521 ttttcacaat tctattgaca aagacataga aacttggcag tgtcactaga gctactagct
    50581 gaaccaaatg aaagagattc ttgaccactg cgaaatggtg cagaccagct gctgacgaac
    50641 gaaaatcagg catctgtaag acctgactaa aaggattggt cagataattc atcaagatat
    50701 gaaaattgta ttgaatggtt tctggtttta gatagactcg attcgttaag tttagccact
    50761 gaatctccat aggatagaaa atccaagcca gataaatggt cagaaggatt gagagggaga
    50821 ggagaaagag catagagccc caaaagatca atttagtttt catcaaaatc ccactccgca
    50881 aggctagaaa ccacatgtgt cggtgcgatt ggcaggccag ctacttcttc tgccttagta
    50941 aaacctgtcg tcaccaagag cgttggaatg ccattgtcaa tcccagcccg gatatcagtc
    51001 aaataattgt ccccaaccat aattaactct tcacgttcca aacctaagtg ctcaaccgcc
    51061 ttgtccataa tgatggcatt gggttttccg atataaaccg gcttcactcg tgtcgctact
    51121 tcaagcagcg taatcaggga gccagcacct ggcaaaagac cacgttccgt cgggatgttg
    51181 aggtcaggat tggttccgat aaaatgggca cccttttgaa tagcaagagt tgctgtggca
    51241 aatttttcat agtcgacttg ccaatccaga ccaactacca cgtaggcagg gttttccttg
    51301 tcttccacat aaccagccgc cttgatggct tccttgagtc ctgcttctcc gacgacatag
    51361 acggtctttt caagccccaa atcattcata tagtcgatgg ttgccaaagt cgctgtgtag
    51421 acagtcgata ggggcgtatc gatattaaaa ttctgagcca acatctcctt aacactctct
    51481 ggagtgcgag ttgtattgtt ggttacaaag agatagggaa tgtcccgctt ttgcaattca
    51541 tgaacaaaag tctctccagc agggattcgg tctttcccct tataaatggt tccgtctaaa
    51601 tcaattaaat agcctttata tttcatctat ttctccctaa gcctttttta tttctttcca
    51661 agtaatgatt gcttgggcat tgataacccc atcacttgta atttcatgct tgctttccag
    51721 tccagtccgt tcaacagccg atgtaatcac cccacctggt cgaacttcct tgacatactt
    51781 gaggttgatt ttcttgggaa tatagtgggt caaaaaatcc gctcccatga cctcaaaaat
    51841 ccagtccaag tatttactgt tattgacatg accattcata tccaagtcgt aaaaacgaac
    51901 atggtaatcc ttgctgatcg gctcttccaa ggactcatac ttcggtccac ggataagttt
    51961 tttatcaaaa tcagactggt aaggagccac aatctcaggt tcaacagcat ggacttttcg
    52021 actgtcgcgg tccatgagaa caaaggtcgc catcatatgg atgagctcct gccccgcttc
    52081 attataaata gtaaagcgac ggtagcaaaa aagtcgattg tagctcaagg cttccgtttc
    52141 gatggtaatt tcttccgcaa aacgaggcaa acgaaccacc tcaatatcat attctgcgat
    52201 aatccagacc agattatagt cttccaaaat ggccttatca ctaactccca gttcaatcga
    52261 ctgcatccct gaaacttgca gtgacagcaa aatcacatct ggaagtttga tatgaccgtt
    52321 catatcagcc atatcaaaag gaattttcat tttcatttga taagttaagc ccatgatcct
    52381 actccaaaat aaatcgttct gctacagtat ctcccaaaaa gagacctctc tttgtcatgc
    52441 gaacgtggtc accctcaatc tgcatgaggc cttgttgaac caaatctctg acaatttctc
    52501 cataaagtcc agcaaaagac tgtccaaatt tttcctcaaa tcgcgccatg gaaaccccgg
    52561 atttcttgcg gagtcccaag aacatttctt cttccatttg ctccttttga ctcaggtgat
    52621 cttctgtaat acaagcattg ccttcctcaa ccgcactgag ataatgacga atgggaccat
    52681 gatttttata acgtactcca ttgacataac cagatgcccc tgcaccaata ccatagtatt
    52741 cagcattgtc ccagtacatg agattatgac gactttcaaa gccgggtttg gagaaattag
    52801 aaatctcata atgctcaaaa cccgctcgct ccagctctgc aatgatgtac tcaaacatct
    52861 ccgcttctag ttcctcctta ggcagaggca atttcccacg tcgcatccgg ttcataaaga
    52921 ccgtatggtt ttctaaaatc aaactataca aactcatgtg gggaatatcc agtccaatgg
    52981 ctttagccac attttccttt acttgctcca tggtctgacc aggcagagca taaatcaaat
    53041 caatggagat gttgtcaaaa ccagccagtt tcaggcgatc gatattttca taaatatcct
    53101 tctccaaatg actgcgccca atctttttca acatcttatc atcaaaggtc tggacaccta
    53161 gcgaaacacg attgacagcc gaatttttca aaacagctat cttatccgca tccaaatcgc
    53221 ctggattggc ttcaatggtc aactcttcca agacagacaa gtccaagttt ttagtcaagc
    53281 cattcagtaa aacctccagt tgcggagccg acagggctgt cggtgttcca ccaccgatat
    53341 aaagggttga caacttttca atatcataag aacgaaactc ttccagcaga tgctctaaat
    53401 agctgtcgac tggctgattt ttgatgaaga cctttgaaaa atcacaataa taacaaatct
    53461 gggtacaaaa tgggatgtgc acataggctg acgttggttt tttctgcata gtaattatta
    53521 taccacaaag actagattcc agataaaaat caccatcccc agatacatag tccgtccgga
    53581 gatggtgatg gtttattctt ctgttatatc aatcacaatc tcttctgagt catcaagagc
    53641 ttcggctttt tcttgccatt gctccttgag attatttaat tgattttttg atgcttctgt
    53701 cgcttgaaga gcataggatt tagcttgagc aagtatactg tccacagtga tttcacctga
    53761 ctcaacctgt tcttttgttt tcagaacaaa atctgtagcc tgctccttaa cttctgtcag
    53821 tttttcacag acttgctcct tggcatactc cggatcttct ctcaaatcat ctagaaaatc
    53881 ttgagcctga ctgcaaactt gtttgccctt atcacttgtt aaaaacaagg caagagctgc
    53941 acctgaaacg gttcctaaaa ggattgagga taatttaccc ataaggattc tcctttttta
    54001 ttttttgaaa aatttacttg caagacgaag agctgacaga cttgcaccag tcttgagtgt
    54061 ttttgaacca gctgatgaag ctttcttgct caagacacgc gcatggtcat tgaggtctga
    54121 aacagataga gataaatctg caacagcact gaagagtgga tcaatcgtag ccaccttgac
    54181 attgatatca tctgccaaga cattgacctt agccaacaac tcattggtgt gatgcaaggt
    54241 cacatccaca tctgaagtca aggttttaat cgtcttttct gtttcatcga tgacacgacc
    54301 aagcttttgt acagtaatga tcagatagac caaaaagaca atcaaagcta gggcaacaag
    54361 aatatatgca acttctaaca tttagttttc ctcctctgta atatagtaag gggccttctt
    54421 tcgattttga taaataacga tcattatacc gagaccgata aggacaactg acagccattg
    54481 ggacactcga aggccgaaga acatgagact atctgttcgc ataccttcga tgaccatacg
    54541 accgaaacca taccaaatca agtaaaaggc cgtgatatga cctcgtctga gactcttcca
    54601 tttccgtcta aaaatcagaa tcaaggcaaa gccaagcaga ttccatagag actcataaag
    54661 gaaagtcggt tgacggtagc tcccctcaat atacatctgg tcacggataa agccaggtag
    54721 ataatccaga ttatccactg ttgcaccata agcttcttgg ttaaagaaat taccccaacg
    54781 ccccaaactt tgagcaatca taacgctagg cgccgcaata tctagaaaat cccaagtatt
    54841 gatgagttta cggtcagcaa agatatagag cacaagagcc ccagttatca aaccaccgta
    54901 aatggccaaa ccaccattcc aaatggcaaa aatctctcct aaattctgac tatagtaatc
    54961 aaatcggaaa ataacatagt agagacgagc tcctaaaata gccaagggaa aagctactaa
    55021 gataaaatct aaaatatcgt ctggtatgat cttctttcta ggtgcttctt tcatggtcaa
    55081 ataaaccgca agaatcaagc ctgtcacaat acataaggca taccaacgaa tggctagggg
    55141 tcctagttga atagcaattg gatcaagcat tttgcacctc atttcgagcg atgagacttg
    55201 tcagtcgttc gtcgaacaaa cgggtcgcat caaagcccat ttccttggca cgataattca
    55261 tggcagctgc ctcaatcaca acagagatat tacgacctgt tttaactgga atacgaatac
    55321 gaggaatggc tacgccagaa acttcaagtt cctctgcatt gtttccaaga cgatcaaagg
    55381 tcttatgcgt atcgtaattt tccaaataga cagcaagctg aacctgtgaa gaatccttga
    55441 cagcactcgc accgtagaga ctcataacat cgataatacc aaccccacga atttcaatca
    55501 agtgtttcaa aatttcagct ggttcacccc agagagtaat ctcatccttg gcaaagatat
    55561 cgacacggtc atcggctacc aaacggtgac cacgtttgac aagctcaaga cctgtctcgc
    55621 tcttaccaat tccactatct ccctgaatca agacgcccat cccataaata tccatcaaga
    55681 caccgtgcac actggtacgt tctgccaaac gagaatccag atagctagat aactctccag
    55741 ataaacgact ggtagctgca cggctggtta aaatagcaat cttacattct ctagcagcct
    55801 ttaacatctc ctctggaacc accaaaccac gggcaacaat gactgctggt gtctcaggta
    55861 gaaacatttt tttcaaaact tcataacggc tgttggaagg catgctgatc agataagacc
    55921 actccttcat ccccaaaagt tgaatccgct ctggtgtata gtagtcaaaa tagcctgtca
    55981 tttcaagacc aggtcgcgta atatccgctg tattgatttc cttttcaagc aattttggtt
    56041 caccatagac aatgtctagt ctaagctttt caatcacttc ttttactaaa accgacatca
    56101 tttcctcctt caaatgagtt cttctctcta ttatatcaaa ttgtaggagg aagtttcaga
    56161 tttttgcagg ctttggagta tttatttaaa agaaaaagga ctagatttct ctagcctttc
    56221 attccaatta gaatttttta cgtttacgag ctacttctga tttacgttta cgttttacag
    56281 aaggtttttc atagaattca cgtttgcgtg tttcttgaag agtaccagct ttagtaaccg
    56341 cacgtttgaa acggcgaagt gcgtcgtcaa gagattcatt cttacgtact actgttttag
    56401 acattttttt cactcccttc aagttcaata tctatttcat tctacacgta aaaggaataa
    56461 ttgtcaagca aaaatgcggt ttaattttga ttttttcttc catttataca agagttgaaa
    56521 gcgttcaata gaacattgct tttttatttt tcgagtaagc taagcgcttc agcatctgcg
    56581 atgatggtta catcagggtg attttggagg ctacttgcag gtaggttctc agtcactggg
    56641 ccagatactg ttccggcaat ggcttctgct ttcgactcac cgtaagcaaa aagaataata
    56701 gacttggcat ccaaaatgtt tttaatcccc attgaaatag cttgggttgg gacgtcttca
    56761 atcttggcaa agaagcgtgc attggcttcg atagtagact ggtcaagttc tactagatgc
    56821 gtttgactgt caaatggagt accaggctca ttaaagccga tatgcccatt gcgaccgatt
    56881 cccaagattt ggaggtcaac tggatggtca gccaaaattt ggttgtagcg ttcaacttca
    56941 gcttcagcat tgtccttaac accacgaggc aagaaacttt ctttaaatgg tttttggttg
    57001 aacaagtttt cttgcatgaa gtaacgataa gactgtggat tgtccccatc aaggcccaca
    57061 tactcatcaa ggttgacact ggttagattt gaaaaatcaa ggtcactctc aacaatttcc
    57121 ttgtaaaatt caagtgggct acttcctgtc gcaagtccta gagtttgagc tccattagcc
    57181 aatttttcct tcaaaatctc aaaagcaact tttccacctt gaacttggtt ttcaactcta
    57241 ataactttca tcttttcatc ctccatttct gtctatattt attatatggt atagaccaat
    57301 ttttgtcaag tgaaaacgat ttaatttcta aaaaaagagc gtccaaactt gaaacgtgtt
    57361 ataatggata ggattagaac ttagaaagaa tgaacagata tatgaataca gctgattttg
    57421 atttccactt gccagaggaa ttgattgccc aaacgcccct tgaaaaacgt gatgcctcca
    57481 aactcctcat cgtcaaccgt gagacaggag aaatgcaaga taaacacttc cactctatta
    57541 ttaatatgct ggaacctggt gatgcccttg tcatgaacga cacccgagtt ctccctgccc
    57601 gcctctatgg tcaaaaagtg gagacaggag gtcatgtgga acttctcctc cttaagaaca
    57661 ctagtggaga cgagtgggaa gttctggcta aacctgccaa acgcctcaag gtcggtactc
    57721 gtatcagctt tggtgatggc cgcctcagcg ctgtcgttac agaagaattg acccacgggg
    57781 gacgcattgt ccgctttgaa taccaaggaa ttttcctaga agtcttggaa agtctgggag
    57841 aaatgcctct gccaccttat atccacgaaa aattagatga ccgtgaacgt tatcaaaccg
    57901 tctacgccaa ggaaagcggc tctgctgcag caccgactgc tggtcttcac ttcaccaaag
    57961 aactgctggc agaaatccaa gctaagggtg ttcatctagt ctatctgact ctccatgtcg
    58021 gactcggaac ctttagacct gtttctgtgg ataatctgga cgaacacgaa atgcactcag
    58081 agttctatca actttctgag gaagctgctg ccacccttcg ctctgtcaaa aaaaatggtg
    58141 gtcgtgtcat cgctgtcgga accacttcta tccgcacctt ggaaactatt ggttccaagt
    58201 ttgatgggca aatccaagca gattctggtt ggaccaatat ctttatcaaa cctgggtatg
    58261 agtggaaggt cgtggatgcc ttctcaacca acttccacct gccaaaatca actctggtca
    58321 tgttggtttc tgcctttgca ggccgtgaat tagtcttaga tgcctaccac cattccatcc
    58381 aagaacacta ccgcttcttc agttttggtg acgccatgtt tatttattga gaaagaattt
    58441 ctctaaatct tctaatacca ataaatcgct aagatattat ttcaaagaac atctacaatt
    58501 gaaactctag ctagctgtag aagaggtcta gtacattgaa attaaaatgc ttccccctag
    58561 cttcgaaaat attgccatag attgcgttga ctctccaaat tgattcatct atattttatt
    58621 tcagcttcct atactttctt cgctgtttgt aaatcaaaat gcaagacaca tgagtagcac
    58681 catatttgtt actcttatct gtcctctcaa gagactatta tgagttattt cagaatcatt
    58741 cactactttg accctgactc tccttagtct caaaatcaaa gacttatact cttcaaaaat
    58801 ctcttcaaac cgcgtcaacg tcaccttgga ttatatatgt gactgacttt gtcagttcta
    58861 tctacaacct caaagcagta ctttgagcaa cctgcgacta gttttctagt ttgctctttg
    58921 attttcattg agtattaaac aaaaagtgaa caaagctgaa ttctaatgta cagaagacta
    58981 ggcttgttca cttttttata gtcgctataa gatgacctta tctatagctt tttatatata
    59041 attatatatt cagacatact attatcaatt ttgtctcagg gaggaatctg ttaacgcacc
    59101 cattcaccat tatcattgac tctatagcca tctatacttg tattgaccgc taactcaccc
    59161 gatgcattta cataatacca tttaccacca acttggaacc attgattaac tttcatagaa
    59221 ccgttgctgt tgaggtagca ccatgaacca ttaacttgta cccaacctgt tgccatggaa
    59281 ccatcagtat tataaaaata ccacatacca ttttcttgtt tccagcctgt tgttggagca
    59341 actgctttag ctggttctac tgctacatct gttccttggt tagatgtaac agatacagga
    59401 tacgaaggaa tagatgattg ctcaggaaca acaacttttt caggttctct cgtccctctc
    59461 cttatacgtc tttttaccat ctctttagta atttgacgag aagtagtttc ttcaattgtt
    59521 ccatcacgtt catctacagc atagattgta gtaagagtaa ttttaccaat ttctcctact
    59581 tcttgacctt tatcaagagt tgggtcatcg agatattctg tttcgattgg aatttcttgg
    59641 acaagaactt ggggcttggt tcctttttta acaactcttg tttgagagtc ttctttttga
    59701 cttaaagtac tctcagttac ttgtccactc tttccatcta catcataagt tatcgttgta
    59761 actgttttcc cattctttcc tagagtaatc tcttgctcct gtcctgcaga aaggtcattg
    59821 tctgcttcat atttagtagc acatggaaca agaacttctt caaccttgct tttagctgga
    59881 actttgataa ctgtatccgt ggcttctttt ctatcaacag taacctgttc ggtaacatga
    59941 ccagtctctg gattaacatc gtaggtcctt gtcgtagtta catagccatc ctctccatca
    60001 attgtaacag gattttcact acggtctttt gtttcatctt tttcataacg aattcgcgta
    60061 cttgaaattt tcttggttac taccttaggt ttagtcgcta cttttacaat aatatcccca
    60121 ttgtcagcgt catcatactc tattccctct tctttatctc tagtatcatc tctgacatat
    60181 tgaatcccat cagcagcatg aacaaaactt gtattcagat tcctcctaaa aataaagtta
    60241 gcccgattac cgcagaacca aaaatctttc cgagtttacg taatgcatag cgcttattgg
    60301 tattagattt tgccattaca tcctacttct aaaagttact acttctagta tagcatcttt
    60361 tctatcaaac gttaaacagt atactttata tatcaaatat acttagaatg atatattgat
    60421 tattgaacta acgctttaac tatatcgtaa tcaatctcat atataaagga ttgcagacat
    60481 cttatctaaa tacatgctaa tatatttaga tacaaacatt ccaacttgat aactttcact
    60541 catctttcat cattccttat acaactatgc agtataaata gaatagtttt ctcatcagaa
    60601 tgagactatt ttaatattag atattttgat agaaaaaaca tgaataaaat tggttgaatt
    60661 taattcccta actcgataga ggattctatt ttaaatttaa caacagctag gattacacta
    60721 taaaaagtac attaccacct gttcggctgg agaatctagt cgattagctc cctcttagtt
    60781 acaagcttaa agcgattttt taactaatac taaaccagat taaagaagga actagaacat
    60841 ctgtcttgta ctaatcaata tgctatttta aagtttcaaa taaacttgga atgctaatta
    60901 ttatatttac aataaatagt tgacttcgat agaaacagaa aatagaattc aacattcttc
    60961 cctacttata ccataataaa taagatccgc aagatagcct tttctctcta caccattaac
    61021 aatggtttgt agataggaca ttccagcctt ttccatgaca cgacctgaag ctgggttgag
    61081 actggcataa cgtgctctga ccttttgaaa acctgcttga gtaaaacaaa agtccaagat
    61141 agctttcaaa gtctctgtca tcataccatt tccccagtaa gccttgccta acacatagcc
    61201 aatttcacag cttaaatcag cctcgtctat cttaacaatg ctgatatctc ctatcacttg
    61261 ctctgggttt tcttttagac aaatggccca tttataatag ttgagattag tataggaagc
    61321 aacccaattg caaatcgagt ttcgagtgat ttcgacatca ggatggggat cccaggtaac
    61381 ataggtcaga ttctcagcgg atgaagccca attttgaaac atggcttctg catcactctc
    61441 cacaaatctt cttaaaatca aacgttctgt ctgtaatatt tgcgtaccga tagatttcat
    61501 gatgctacct cacttcctta tttctatgct cgtagtaaaa aggctcaact cagtaacagc
    61561 tagaaaacga gtttgtcttc taatttcttg acgcagtcgc tgcctggttt gaaatgcgct
    61621 ctagcaatct ttttcaaacc tagtcatcgt tgcaggggta agacgatgaa atcgaactct
    61681 tcgagttacc gaatctgcct cattttctta tttcaagatg agaggctgaa aacctccagt
    61741 ggaggttttt cttgcttttt aatttcaggg caagaagcta aaaaggtccc ccggaccttc
    61801 ttcgctttct catttctagg ctcagggtaa aaacctccaa tggaggtttt tactcccaaa
    61861 agtcatcaaa tacggtgatg ggtaagtggc gtttgtgttg gcctttgtgc caccagtttt
    61921 caatggtcgc ttgagcttct gggctgattg ttttgccttc taggtaatcg tcaatctctg
    61981 cataggtgac tccaagtgcg acttcgtcag ctaggcctgg tttgtcttct tctaggtctg
    62041 ccgttgggat tttttcataa agggctgggt ctgcaccaag ttcctgtaag agttgttttc
    62101 cttgacgttt attgaggcgg taaagaggga gaatatccgc accaccgtca ccaaacttgg
    62161 taaaaaagcc tgtgatattt tccgcggcgt ggtctgttcc aatgaccgct ccgctatggg
    62221 aaccagcaag ggcatactga gcaatcatac ggcaacgtgc cttgatattc cccttgttga
    62281 agtctgaaac aggactacct gtcgcttcaa ctgcagctgt catggtatca gctgattcct
    62341 tgatattcac aaccaagctg acatctggct ggatgaaggc tagggctttt tgagcatctg
    62401 cttcatcagc ttgcactccg tatggcaggc ggacagcgat aaatttgtag ctgtcgtctc
    62461 ccgtttcagc tcgcagttct tccatagcta attgcgccaa acgccctgcc aaggttgagt
    62521 cttgtccccc agaaatccct agtacaaagg tttttaggaa gggatgtttt ttcagatatc
    62581 tttttaagaa atcaatagaa cgacggattt cttcctgggc atcaatcact ggtttgacac
    62641 ccagctcttg gataatcgtt tcttgcaaac tcattcttct tctccttcac caagggcttc
    62701 cttgcgcatc ttatcaatca agtccatctt atcttgccat acatcacgcg ccaaatccac
    62761 tggatagtgc tgcggattga gcacacgctt atactcatcc cacaacttgt caaattcctt
    62821 acgggcataa tcctgaatgt cagtcaaact aggcaagttg taaactaata ttccttcttt
    62881 gaagatatcc accaagagag gaacggcatc aaaattacga accgtcttct tgatgtatgt
    62941 ataggtcgga tggaacatct tgatttctgt catgtcgcta atatccacac catcataagt
    63001 gatgtagtca ccttctgact tgcctttttc acgactggta atgcgccaca cctgcttctt
    63061 acctggcgtc gacacttttt ccgcattatt agacagctta atcgtattgc gcatctgacc
    63121 agtttcatct tcaattgcaa caatcttgta aaccgcccca agagccggct ggtcataggc
    63181 tgtaatcagc ttggtaccca caccccagac atcaatcttg gccttttgca tcttgaggtt
    63241 aaggatggta ttttcatcta gatcattaga agcataaatc ttagcctctg taaatccagc
    63301 ctcgtccagt tgctgacgga ctttcttaga aatgtaggca atatccccag agtcaatccg
    63361 cacacccata aagttaatct gatcacccag ctcacgcgcc acctgaatgg cagctggtac
    63421 accgatgcga agggtgtcat aggtatccac aagaaagaca caatttttgt gggtcgcagc
    63481 gtaagccttg aaagcttcat agtcattgcc ataaacctgt accaaggcat gggcatgggt
    63541 tcccaaaaca ggaatgtcaa agagcttacc cgcacgcacg ttgctggttc cattggcccc
    63601 accaatcacc gctgcgcgtg ttccccagat ggccgcatcc atttcttgag cccgacgtgt
    63661 cccaaactcc atcaagggtt catcttcgat aaccgaacga atacgagctg ccttcgtcgc
    63721 caccaaggtc tggtagttga cgatgttcaa aagagccgtt tcgaccaact gacattgggc
    63781 tagaggtcct tccacctgca caatcggttc attagcaaaa accaaatccc cttcttgggc
    63841 agaacgaacg gtcaactcca acttgaaatt gcgaaggtaa tccaagaacg ccccatgata
    63901 accaagcgac tccaaatagg ctatatcact atctgaaaaa cgtaggtctt caagatagtt
    63961 cacaattctt tccaaacctg caaaaaccgc atagccgttc ttaaaaggct gttggcggaa
    64021 atacacctca aagaccgcct tcttattgtg aatcccttgg tcaaagtaaa cctgcatcat
    64081 gttgatctgg tacaagtccg tgtgcaatgt caaactatca tctggataca tacttttcct
    64141 acttccttag ctagaaaccc atgaaaattt tcaagaactt tcatgtattc caataaatta
    64201 gtactattat atcacatttt agctggattg agaaaagagt aacaagctat tctccactct
    64261 ccaattcatc catatcttgt tcaaattttt tctgagccca ttcgccatag ctcttaagac
    64321 caagattgcc aataaagacc cacggaaggt aaatgacata tgtaatgacc ccagcagaca
    64381 ggtatttaaa attcaaagga ttgtgctgat aaatttctat gttgaattga taattctgca
    64441 acatcaaaag agccgtaata gccaaggtta ggaaaaaaca acccaaaatc gtaaaatgaa
    64501 aacgactata gtaggtcact cccagataac gggcgcgatt gaaaaagtaa aatgtcccta
    64561 tgatgataac gattagcagc atattagaat taaaaaggct tggtgctaat actgaaatga
    64621 tataagatag gagcgacaaa gcaatgcaga tatagaaact ttcagagccc gctttattga
    64681 acagttgttc ttctctttcg tctagtaatt gataataata aaatctattt ttcatcttct
    64741 tcctcccaaa atagttggtc tagggttttc cctaaacatc tgcaaataga ctggcagagc
    64801 gagagactgg gattgtattt tcccgcctct atcaaaccaa tagtctggcg tgtcaccccg
    64861 acagcctctg ccagttgacc ttgtgttaaa tcacgctcta cccgagctaa ttttaatttt
    64921 aaatttttag ccaccttcgt cctccttata gttttaatac tcatctactc ttaaaaaatc
    64981 caaaaccaac acaagctatc agctatttat tataacccca ttaatttgca ctccagtatt
    65041 atcttcagcc gaaaatcagt attttaggtt gtttgaaata aacttcctag tttactcttt
    65101 tatttttatt tagtattagc tttagtagaa tcttttaaac gagtttttat tgcttatatt
    65161 tcttgtttag tttagttg
//
LOCUS       DAVLIK010000006        62449 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLIK010000006 DAVLIK010000000
VERSION     DAVLIK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.006"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..138
                     /locus_tag="VXE87_000384"
     CDS             <1..138
                     /locus_tag="VXE87_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0841994.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
     gene            complement(630..779)
                     /gene="rpmG"
                     /locus_tag="VXE87_000385"
     CDS             complement(630..779)
                     /gene="rpmG"
                     /locus_tag="VXE87_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0841995.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(795..977)
                     /gene="rpmF"
                     /locus_tag="VXE87_000386"
     CDS             complement(795..977)
                     /gene="rpmF"
                     /locus_tag="VXE87_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0841996.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            complement(1129..1329)
                     /locus_tag="VXE87_000387"
     CDS             complement(1129..1329)
                     /locus_tag="VXE87_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0841997.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1332..2339)
                     /locus_tag="VXE87_000388"
     CDS             complement(1332..2339)
                     /locus_tag="VXE87_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0841998.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALKRLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2530..4560
                     /locus_tag="VXE87_000389"
     CDS             2530..4560
                     /locus_tag="VXE87_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0841999.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            4564..4848
                     /locus_tag="VXE87_000390"
     CDS             4564..4848
                     /locus_tag="VXE87_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0842000.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4861..6207
                     /locus_tag="VXE87_000391"
     CDS             4861..6207
                     /locus_tag="VXE87_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0842001.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            6211..7068
                     /locus_tag="VXE87_000392"
     CDS             6211..7068
                     /locus_tag="VXE87_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0842002.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDENKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            7065..7997
                     /locus_tag="VXE87_000393"
     CDS             7065..7997
                     /locus_tag="VXE87_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0842003.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8230..9933
                     /gene="ilvD"
                     /locus_tag="VXE87_000394"
     CDS             8230..9933
                     /gene="ilvD"
                     /locus_tag="VXE87_000394"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0842004.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10364..10444)
                     /locus_tag="VXE87_000395"
                     /pseudo
     CDS             complement(10364..10444)
                     /locus_tag="VXE87_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10502..10843)
                     /locus_tag="VXE87_000396"
     CDS             complement(10502..10843)
                     /locus_tag="VXE87_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0842005.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10967..11818
                     /gene="rgg"
                     /locus_tag="VXE87_000397"
     CDS             10967..11818
                     /gene="rgg"
                     /locus_tag="VXE87_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0842006.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            12011..13258
                     /locus_tag="VXE87_000398"
     CDS             12011..13258
                     /locus_tag="VXE87_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0842007.1"
                     /translation="MKLLFRNPAYRILILSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            13336..14625
                     /locus_tag="VXE87_000399"
     CDS             13336..14625
                     /locus_tag="VXE87_000399"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0842008.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFATKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            14616..14696
                     /locus_tag="VXE87_000400"
                     /pseudo
     CDS             14616..14696
                     /locus_tag="VXE87_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14966..15280
                     /locus_tag="VXE87_000401"
     CDS             14966..15280
                     /locus_tag="VXE87_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842009.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            15290..15496
                     /locus_tag="VXE87_000402"
     CDS             15290..15496
                     /locus_tag="VXE87_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842010.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            15496..15693
                     /locus_tag="VXE87_000403"
     CDS             15496..15693
                     /locus_tag="VXE87_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842011.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            15696..16430
                     /locus_tag="VXE87_000404"
     CDS             15696..16430
                     /locus_tag="VXE87_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0842012.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NIIGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            16442..17083
                     /locus_tag="VXE87_000405"
     CDS             16442..17083
                     /locus_tag="VXE87_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0842013.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            17101..17331
                     /locus_tag="VXE87_000406"
     CDS             17101..17331
                     /locus_tag="VXE87_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842014.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            17367..17447
                     /locus_tag="VXE87_000407"
                     /pseudo
     CDS             17367..17447
                     /locus_tag="VXE87_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            17683..19446
                     /gene="aspS"
                     /locus_tag="VXE87_000408"
     CDS             17683..19446
                     /gene="aspS"
                     /locus_tag="VXE87_000408"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0842015.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITESLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVRGVDFKVFSEAPAVKAIVVTGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            19424..20365
                     /locus_tag="VXE87_000409"
     CDS             19424..20365
                     /locus_tag="VXE87_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0842016.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLTFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20575..20655)
                     /locus_tag="VXE87_000410"
                     /pseudo
     CDS             complement(20575..20655)
                     /locus_tag="VXE87_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(20791..21777)
                     /locus_tag="VXE87_000411"
     CDS             complement(20791..21777)
                     /locus_tag="VXE87_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0842017.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21787..22587)
                     /locus_tag="VXE87_000412"
     CDS             complement(21787..22587)
                     /locus_tag="VXE87_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0842018.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22848..23690)
                     /locus_tag="VXE87_000413"
     CDS             complement(22848..23690)
                     /locus_tag="VXE87_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0842019.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(23692..24984)
                     /locus_tag="VXE87_000414"
     CDS             complement(23692..24984)
                     /locus_tag="VXE87_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0842020.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(25095..26366)
                     /locus_tag="VXE87_000415"
     CDS             complement(25095..26366)
                     /locus_tag="VXE87_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0842021.1"
                     /translation="MSSKFMKSAAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26916..28433
                     /gene="malQ"
                     /locus_tag="VXE87_000416"
     CDS             26916..28433
                     /gene="malQ"
                     /locus_tag="VXE87_000416"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0842022.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28459..30717
                     /gene="glgP"
                     /locus_tag="VXE87_000417"
     CDS             28459..30717
                     /gene="glgP"
                     /locus_tag="VXE87_000417"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0842023.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(31762..32334)
                     /locus_tag="VXE87_000418"
     CDS             complement(31762..32334)
                     /locus_tag="VXE87_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842024.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNRRINF"
     gene            complement(33178..34026)
                     /locus_tag="VXE87_000419"
     CDS             complement(33178..34026)
                     /locus_tag="VXE87_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0842025.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNHHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAS
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            34178..34456
                     /locus_tag="VXE87_000420"
     CDS             34178..34456
                     /locus_tag="VXE87_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842026.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            34458..36521
                     /locus_tag="VXE87_000421"
     CDS             34458..36521
                     /locus_tag="VXE87_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0842027.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(36599..37855)
                     /locus_tag="VXE87_000422"
     CDS             complement(36599..37855)
                     /locus_tag="VXE87_000422"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0842028.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADTVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37997..40459
                     /locus_tag="VXE87_000423"
     CDS             37997..40459
                     /locus_tag="VXE87_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0842029.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            40524..41435
                     /locus_tag="VXE87_000424"
     CDS             40524..41435
                     /locus_tag="VXE87_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0842030.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            41665..42363
                     /gene="dapD"
                     /locus_tag="VXE87_000425"
     CDS             41665..42363
                     /gene="dapD"
                     /locus_tag="VXE87_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0842031.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            42431..43561
                     /locus_tag="VXE87_000426"
     CDS             42431..43561
                     /locus_tag="VXE87_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0842032.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            43573..44112
                     /locus_tag="VXE87_000427"
     CDS             43573..44112
                     /locus_tag="VXE87_000427"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0842033.1"
                     /translation="MKSELRKQVLHEMKTLSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            44096..44773
                     /locus_tag="VXE87_000428"
     CDS             44096..44773
                     /locus_tag="VXE87_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0842034.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(44840..45739)
                     /gene="galU"
                     /locus_tag="VXE87_000429"
     CDS             complement(44840..45739)
                     /gene="galU"
                     /locus_tag="VXE87_000429"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0842035.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(45761..46777)
                     /locus_tag="VXE87_000430"
     CDS             complement(45761..46777)
                     /locus_tag="VXE87_000430"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0842036.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            46989..47428
                     /locus_tag="VXE87_000431"
                     /pseudo
     CDS             46989..47428
                     /locus_tag="VXE87_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(47543..47968)
                     /locus_tag="VXE87_000432"
     CDS             complement(47543..47968)
                     /locus_tag="VXE87_000432"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0842037.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(48036..48686)
                     /gene="phoU"
                     /locus_tag="VXE87_000433"
     CDS             complement(48036..48686)
                     /gene="phoU"
                     /locus_tag="VXE87_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0842038.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(48701..49453)
                     /gene="pstB"
                     /locus_tag="VXE87_000434"
     CDS             complement(48701..49453)
                     /gene="pstB"
                     /locus_tag="VXE87_000434"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0842039.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(49455..50270)
                     /gene="pstA"
                     /locus_tag="VXE87_000435"
     CDS             complement(49455..50270)
                     /gene="pstA"
                     /locus_tag="VXE87_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0842040.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(50263..51126)
                     /gene="pstC"
                     /locus_tag="VXE87_000436"
     CDS             complement(50263..51126)
                     /gene="pstC"
                     /locus_tag="VXE87_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0842041.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(51244..52119)
                     /locus_tag="VXE87_000437"
     CDS             complement(51244..52119)
                     /locus_tag="VXE87_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV0842042.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTTKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(52286..53617)
                     /locus_tag="VXE87_000438"
     CDS             complement(52286..53617)
                     /locus_tag="VXE87_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0842043.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(53618..54325)
                     /locus_tag="VXE87_000439"
     CDS             complement(53618..54325)
                     /locus_tag="VXE87_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0842044.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(54409..54711)
                     /locus_tag="VXE87_000440"
     CDS             complement(54409..54711)
                     /locus_tag="VXE87_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0842045.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(54698..54919)
                     /locus_tag="VXE87_000441"
     CDS             complement(54698..54919)
                     /locus_tag="VXE87_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0842046.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            54881..55438
                     /locus_tag="VXE87_000442"
                     /pseudo
     CDS             54881..55438
                     /locus_tag="VXE87_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55753..57444)
                     /locus_tag="VXE87_000443"
     CDS             complement(55753..57444)
                     /locus_tag="VXE87_000443"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0842047.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAKNDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            57580..58026
                     /gene="argR"
                     /locus_tag="VXE87_000444"
     CDS             57580..58026
                     /gene="argR"
                     /locus_tag="VXE87_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0842048.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            58077..60611
                     /gene="mutS"
                     /locus_tag="VXE87_000445"
     CDS             58077..60611
                     /gene="mutS"
                     /locus_tag="VXE87_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0842049.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMENPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            60758..>62449
                     /locus_tag="VXE87_000446"
     CDS             60758..>62449
                     /locus_tag="VXE87_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842050.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT        18193 a        11577 c        13518 g        19161 t
ORIGIN      
        1 gaatcaggtt caatggctac tggttggttt acagtttctg gtaaatggta ctatacctat
       61 aattcaggag atttattagt aaacacgact acacccgatg gctatcgagt caatgctaac
      121 ggtgagtggg taggataggt atccattagc taaatctaat cattctgaac taaaaaatct
      181 tcttacatat gtaggaagat tttttggatt ctcaaaacta gtttaaaaga ctacgctatt
      241 taaaccaatt ttaagaatgg atatataagg atattcagaa atctagttgg tcaacttttg
      301 tattttgaat ataccttaga tggtgacgat gtcttggtat atctggtact cacttacata
      361 ttctaactta ttttaactaa gatacaactg tagttggtga atttgctaca aatagtgtag
      421 aggcgttatt tgaaaaatat acaaaaaagg aaccccaact tacatttgag tttctcttac
      481 ttttaatcgt ccgaatccgt attcttattt caaaaaaggt agtgaaaaat gtagtcattc
      541 gaatgatttc ccttgcaata tagtgaaatt aacaaaaaga aaaaacgctg atcaagcgtt
      601 tttcttctgt attgattcgt attgaatgct tacttaactt ctgtaaacac aacgtgtttg
      661 cgaagttttg gtgagtattt cttcaattga aggcggtctg gagtgttacg tttgttttta
      721 gaagtaaggt acaagcgttc accagattct ttgtgttcaa gtgtaatatt tacgcgcatg
      781 gtatctccct tctattattc agctgatgca gctttagtga ttttacgtcc tttgtagtat
      841 cctttaagtg atacacggtg agaacgtgag taatctccag tagtttcgtc aaagtttaca
      901 gatggagctg ttactttgta gtgtgtacga cgtttgtttt tcttcgcttt tgaagtgcga
      961 cgtgcaggta ctgccatttt gatttctcct ttaggtattt atattcgatt caatctactg
     1021 attttcatca accatactag gataacacat tttttttgta aagtaaagtt acttgacaaa
     1081 aaaagatgaa aaaattctcc tatccgacac ggcagacagg agaaggtgtt aaatatcaat
     1141 ctcaaatggt tcgtcaatgg tttctgatac gtattttccg tctttcttcc gttgcttgac
     1201 acactctgtg aggagatatt cgatttgccc attgactgaa cgaaagtcgt cttctgccca
     1261 tgatgcgagt gcagcgtata actttgttga gagtcgaagg gggatctgct tttttttagc
     1321 ttcagccatc tttagtaaag acttcctgtg ttgacaattg gttgtgcatc atgattgcca
     1381 caaagaacga caaggagatt tgaaaccatg gcagcttttc gttcttcgtc aagttctacc
     1441 aattcccctt cattgagccg ttttagtgcc atttcaacca ttcctacagc accatctaca
     1501 atcatcttcc gtgcatcaat aatggcagat gcttgttggc gttgaagcat aacggcagca
     1561 atttctggag cataagctag gtaagtgata cgtgcttcaa ggatttccaa gccagcatcc
     1621 tcaacacgac tttggatttc ttcacgaata cggttagcaa caatttcgct agagccacgg
     1681 agactacctt catctgcttg cccgtcaccc gtagtatcca cattaggaga cacatcgtaa
     1741 ggatagatgc ggacaatatt acggagggcg ctatcacatt gcagtgaaag atattctttg
     1801 tagttatcaa cgttgaagac tgccttagcg gtatcgacaa ctctccaagt taccgcgata
     1861 ccgatttcta cagggtttcc taagcaatca ttgatttttt gacgagaatt gctcaaggtc
     1921 atgactttga gggaaatgtg tttcttgcca atttcaagat ttacatcatt gtcatttgat
     1981 gatttagctc ctaaaaaagg agattttgtg ctaacatcac cactttgtcc aagtcgagtg
     2041 tggtttgcag ggttgactgc tacgctgaag ggattgacaa agtaaaaacc aggttctttg
     2101 atggtacctg tataattacc aaagagtgtc agaaccagag cttcctgagg tttgacaact
     2161 tttaaaccag catgagctag acctgcaatt acgattagta aaggtccgat aataattcca
     2221 aaaatgtttt ccgaaccaac ccccattata aatataaaga taccaagtac gattgtcaac
     2281 tcaatgagaa tcaatgcgaa tacaccattt ggttttgaat tgattagttt ttcagtcata
     2341 agaatgacct cccattattt gatatctaaa tgatatcact ttgtttttaa aagtcaatag
     2401 aaagttgaaa ataatcacta aaaagtttca gcccaataat ttcttttaaa aggtgagatt
     2461 atattgtgct caaatactct tttattctta taatttttac actataattg tagttagaaa
     2521 ggaagagaaa tgtttgatta tagagcacta gttattttga tgactttgat ggatcattgt
     2581 gagctatcat tatatgaatt atctgttaag gtgagcttac ctataaagga agtcaaagaa
     2641 ggaatagatt atttagtgcc ttatctagct aataaaggga tagtgctgga taaaaagcaa
     2701 ggtcgctata gtttatcaaa tcgtacgaag cagtctttga cagatattat taagtcggat
     2761 gaattggttt taccaaagtc gactcgctta gctttaatct atctttacac tttttgccga
     2821 ttagatttta tatcgaatag tcattaccaa gactttttga aagtaagtaa gaatacaacc
     2881 ttatctgata ttcaatcatt aagaaagatt atgttagata atgatttgga gctagggtac
     2941 agtagagcaa aaggttatac tttacacggt tcagagtgga ataagcaccg cttagctttt
     3001 caaatggtta gtgagttgct ggaatcctcc atagggattt ggggtttgga ttatgtttta
     3061 tccagttggg ggtattcatt aacttatgat ttgattgatc aggtagttaa agattattat
     3121 gagaagctac agctagtacc tattgttaat caattaaaag tttacctttt cggtttagta
     3181 ttcattctgt gtaggtatca aagggatgtt gaaagagtat gtctttcaga gacattagta
     3241 tctcctgtta ttcaagatat aaccactatt ttattggata cagtggttga tttgggaatt
     3301 atagatacgg tgttttctga ggatgattat cgctatatca ccgttttatt atcaagttgc
     3361 tttgaaggtg aagtagatgt tgctccggtt tactttaatc aattaacaga ggctattata
     3421 agtagaatgg aagatatttc tttgttacat tttaaacaaa gggaaggatt gagagaaaat
     3481 cttcgccgcc accttatacc ggcttactat agattaaagt tcggcctacc tagttcaaat
     3541 gaatatgtat tgcatgttaa agaacattat cctgatttat ttgaattagt caaagattct
     3601 ttgatgccct tgatggacgc tattgacaat cccatacctg atagtgaaac agcatatttt
     3661 gttatccatt tcggaggtta tttaaagaaa gcagatactt tgcctcaaaa atggtataaa
     3721 gcagcaatca tttgtcctaa tggtgttagt tcttcattga tgttaaaaga gaatctatta
     3781 gcattatttc ctcaaattga gtttatagga acctcaaaga ttgatgattt acaggtgaaa
     3841 gctagtagtg actatgatat ggttttttct accataaagg tggagacaga aaagccaaat
     3901 tatctagttt cggttatgat gactgaagag caagcaatac aactagtaga actagtgtta
     3961 aaagattttc cgaatttaga gtatggagat tttgagattg aacaaatcct gaatattgtc
     4021 aaaagatatg gaattattac acaagaattg gaattaagat tggcgttaaa gaattatctt
     4081 taccaaaaaa atgatagaaa ggaaattgta ccagtgctag aacaacttat taccaaagaa
     4141 acctatcagg ttagttcgca aaaattagga tggaaggagg cgattcgttt agcagctaaa
     4201 ccgcttttgg atcaagataa gataactgag aactaccctg aggcaatgat tcaaaaagta
     4261 gaagagtttg gaccttttat taatttaggg aagggagtag caattcctca cgctcggcca
     4321 gatgaaggtg tgaatgaaat aggaatgtca atgttagttt tggaagaacc gatttattta
     4381 ttggataatc cagaacaaga ggtaagattg ttgatttgta ttgcagccat tgataatgag
     4441 agtcatttaa aggctttgtc acatttaaca acaattttaa gagataaaaa tcatgttcaa
     4501 actttaatat catcaaaaaa ctataatgat attaaaatga taattaaaca ggaggattag
     4561 ataatgttaa aaattggtac agcttgtggt tcaggattag gttcaagttt tatggtacag
     4621 atgaatattg aatctgtatt gagtgatttg aatgtttcgg atgtagaagt tgaacattat
     4681 gatttaggtg gagcagatcc aaatgcagct gatatttgga ttgttggtcg tgatctagct
     4741 gattcagcta gtcatcttgg agatgttcgt atcttaaata gtattattga tatggatgaa
     4801 ctacgagaat taattactaa actttgtgaa gaaaaaggac ttatatagga ggctagcgtc
     4861 atgatgaagt tcatattgga tattgttagt acaccagcta ttttagtagc tttaattgca
     4921 attttaggat tagttcttca gaagaagaaa ttacctgata ttattaaagg tggaattaag
     4981 acctttgttg gtttcttagt tgtatctggt ggtgcaggaa ttgtacaaaa ttctttaaat
     5041 ccatttggta ccatgtttga gcatgctttt catttatctg gcgttgtgcc gaataatgaa
     5101 gcaattgtag ctgtagcttt aacaacatat ggctcagcta ctgcaatgat tatgtttgca
     5161 ggaatggtgt tcaatatctt aatcgctcgt tttactcgat ttaaatatat ttttttaaca
     5221 gggcaccaca ctctatatat ggcatgtatg attgcggtca ttttatcagt tgctggcttt
     5281 actagcttgc ctctcatctt actaggagga ttagcactcg gtattattat gagtatttcc
     5341 ccagcatttg tgcaaaaata tatggttcaa ttaactggaa atgacaaggt ggctttaggt
     5401 catttcagtt ctttgggata ttggttgagt ggttttactg gtagccttat cggtgacaaa
     5461 tcaaaatcaa cagaggacat taaatttcca aagagtttag cttttttacg tgatagtact
     5521 gttagtatca ctttatctat ggcagttatt tacattattg tagctatctt tgcagggtca
     5581 gaatatatag aaaaagaaat cagtagtggt acaagtggtc tagtttatgc tttacaatta
     5641 gcaggtcaat ttgcagcagg ggtatttgtt attttagcag gtgttcgcct tattttgggc
     5701 gaaattgttc cagcctttaa aggtatttca gagcgtcttg tacctaattc aaaacctgct
     5761 ttggattgtc cgattgttta tacttatgca cctaatgcag ttctaattgg atttatctct
     5821 agttttattg gtggtttagt aagtatggca attatgattg cttcaggaac ggttgttatc
     5881 ttaccaggcg ttgtgcctca tttcttctgt ggagcgactg caggtgttat tgggaatgca
     5941 tctggtggtg ttcgtggagc cactattgga gcatttttac aaggtatttt aatcagtttt
     6001 ctcccagtct ttttaatgcc agttttggga ggactcggtt tccaaggatc aactttctca
     6061 gatgcagatt ttggtctatc aggaattatt ttaggaatgt taaatcaatt tggctcacaa
     6121 gcaggcattg tgattggtct tgttcttatt ttagcagtta tgtttggagt atcctttatt
     6181 aaaaagccat ctgcaaagga ggaataaggg atgattttaa gtaaaaatag agaagatgag
     6241 ttaagaaaat ttgcgactaa catccgatta aatactctta gaacattgaa tcatcttgga
     6301 ttcggacatt acggaggaag tctgtctatc gtagaagttt tagcagtgct ttatggtgaa
     6361 ataatgccaa tgactccaga aatatttgca gcacgagata gagattattt catattatca
     6421 aaaggtcatg gaggaccagc tctatacagt acactctatt tgaatggttt ctttgacaaa
     6481 gaattcttat attctttaaa tacaaatgga accaaattac cgtctcatcc tgatagaaat
     6541 ctaacgccag gcatagatat gacaacgggc tctttaggac aaggaattag tgttgcaact
     6601 ggacttgcat atggtcagag aataagaaag agtccctttt atacttatgc tattgttgga
     6661 gatggtgagt taaatgaagg acaatgttgg gaggctatac agtttgcttc tcatcaacag
     6721 ttatccaact taattgtatt tgttgatgag aacaaaaaac aattagatgg ttttacaaag
     6781 gatatttgta atccaggtga tttcgtagaa aaattttcag catttggatt tgaatccatt
     6841 agggtcaagg gttcagatat tagagaaatt tatgaaggga ttgtccaatt aaaacagtca
     6901 aataattcat cacctaagtg cattgtatta gatactatta aaggtcaagg ggttcaagag
     6961 ctggaagaaa tgaaatccaa tcatcatctt cgccctactg tagaggagaa acaaatgtta
     7021 acttcagttg tagaaagatt aagtcaggaa ttggaggaaa cagaatgatg agaagtacga
     7081 aagaattacg gcatgtatat agagacttcc ttttagaggc taatcaaagt gattctgata
     7141 tagtagtctt agaagccgat ttgtcaagtt cgatggctac tcataatctt gaaaaggact
     7201 ttggagaccg ttatgtgaat gttgggatta tggaagcaga aatggtcggc cttgcagcag
     7261 gcttgtctat tcaggggttt agaccttatc ttcatacatt tggtcctttt gcttcacgaa
     7321 gagtatttga tcaattattt atttctcttg gatacgcaca attggatgcc actgtgattg
     7381 gatcagatgc aggagtaact gcagaaatga atggtgggac acatatgcca tttgaagaaa
     7441 ttggattgtt acgtttaatt cctaaatcga tcatttttga agcaactgat gatattcaat
     7501 ttcgtgaaat attgaaccag acattagact taaaaggact aaaatatatt cgaacaatta
     7561 gaaaagctcc agttcctgtg tatcaaggtg gagaagattt ttctaaaggc tacattgagt
     7621 taagacacgg ggaagatctt gtaatcgttg cttctggtat aatggttgct ccaagtattc
     7681 gagttgcaga tgaactgtct aaattaggtt actcagtagg tgtgatagat ttatttagaa
     7741 tcaaaccgat accagaacag ataaaaacaa tgttaagtgg aaaaactata tttactgtag
     7801 aaaaccacaa tcagataggt ggaattggca gtgctttatg tgaattattc tctgatgatg
     7861 gaataacaaa aattcatcgg atgggggttc aagaaagatt cggtcaagta gggaaaatgg
     7921 attatcttct taatgagtat ggtttgagtg aatcgaatat aaaagagaag gttctagaaa
     7981 tttataatgc aagatagatg ttaaatacac ttatctgaaa gaatttctgt aaaaattaca
     8041 ttacgttatt taaagaaagc ggattaaaaa gcatattctg gtcatcagaa agtgcactaa
     8101 tccgctttgt tgtttttaat tttaaatatt tcacatgcgt atagaatttt ctgaaaattc
     8161 aagaatttta ttctgttcat tgcctttaaa ttgtgctata atagtaaaaa ctgaaatggg
     8221 agggataaga tgactgaatt agataaacgt caccgcagta gcatctatga cagcatggtt
     8281 aaatcaccta accgtgctat gcttcgtgcg actggtatga cagataagga ctttgaaaca
     8341 ccgattgtgg gagtgatttc gacttgggcg gaaaatacac catgtaacat tcacttgcat
     8401 gatttcggga aactggctaa agaaggtgtc aaatctgcag gcgcttggcc tgtacagttt
     8461 ggaaccatta ccgtagcgga cgggatcgct atgggaacac ctggtatgcg tttctctcta
     8521 acatctcgtg acatcatcgc ggactccatc gaggcggcta tgagtggtca caacgtggat
     8581 gccttcgtcg ctatcggtgg ctgtgacaag aacatgcctg gatctatgat tgctattgct
     8641 aatatggata tcccagccat tttcgcctat ggtggaacta ttgcaccggg aaatcttgat
     8701 ggtaaagata tcgacttggt ttctgtcttt gaaggtatcg gaaaatggaa ccacggtgat
     8761 atgacagctg aggacgtgaa acgtcttgaa tgtaatgcct gccctggccc tggtggttgt
     8821 ggtggtatgt atactgctaa taccatggca actgctatcg aagttctagg gatgagtttg
     8881 ccagggtcat cctctcaccc agctgaatca gctgataaga aagaagatat cgaagcagca
     8941 ggacgtgctg ttgttaagat gttggaactt ggtctcaaac catcagatat cttgactcgt
     9001 gaagcctttg aagatgctat cactgtaacg atggctctcg gtggttctac aaacgccact
     9061 cttcacttgc tcgccattgc ccatgccgca aatgttgact tgtcacttga ggacttcaat
     9121 acgattcaag aacgtgtgcc tcacttggcc gacttgaaac catctggtca gtatgtcttc
     9181 caagacctct acgaagtcgg tggtgtccct gcggttatga agtatttgtt ggcaaatggt
     9241 ttccttcacg gagatcgcat cacatgtact ggtaagactg tagctgaaaa cttggctgac
     9301 tttgcagact tgactccagg ccaaaaagtt atcatgccac ttgaaaatcc aaaacgtgcg
     9361 gatggtccgc ttatcatctt gaacgggaac cttgctcctg acggtgcagt tgccaaggta
     9421 tcaggtgtta aagtgcgtcg tcacgttggg ccagctaagg tctttgactc agaagaagat
     9481 gcgattcagg ccgttctgac agatgaaatc gttgatggcg atgtagtcgt tgttcgtttt
     9541 gttggaccta aaggtggtcc tggtatgcct gagatgctgt cactttcttc aatgattgtt
     9601 ggtaaaggtc agggagataa ggtggccctc ttgacggacg gacgtttctc tggtggtact
     9661 tatggtctgg ttgttggaca tatcgctcct gaagctcagg atggtggacc aattgcctat
     9721 ctccgtaccg gcgatatcgt tacggttgac caagatacca aagaaatttc catggccgta
     9781 tccgaagaag aacttgaaaa acgcaaggca gaaacaacct tgccaccact ttacagccgt
     9841 ggtgtcctcg gtaaatatgc ccacatcgta tcatctgctt cacgcggagc cgtgacagac
     9901 ttctggaata tggacaagtc aggtaaaaaa taaactcata ctcgaaaatc tcttcaaatc
     9961 acgtcaacgt cgccttgccg taggtatggt tactgacttc gtcagttcta tctacaacct
    10021 caaaacagtg ttttgagctg acttcgtcag ttctatctac aacctcaaaa cagtgttttg
    10081 agctgacttc gtcagttcta tctacaacct caaaacagtg ttttgggctg acttcgtcag
    10141 ttctatctac aacctcaaaa cagtgttttg agctgacttc gtcagttcta tccataactt
    10201 caaaacagtg ttttgagctg acttcgtcag ttctatctac aacctcaaaa cagtgttttg
    10261 ggctgacttc gtcagttcta tccacaacct caaaacagtg ttttgggctg acttcgtcag
    10321 ttctatccat aacctcaaaa cagtgttttg agctgacttc gtcagttcta tccataactt
    10381 caaaacagtg ttttgagcaa cctgcggcta gttttctagt ttgccctttg attttcattg
    10441 agtatcaaaa agcaagccat tttcggcttg cttttttcat ctttaaaagt gattggcctg
    10501 cttaacgagg tggtagtcca agggcaatac ggccatagcg actgattcgt gtgattttcc
    10561 aagcaggcga ccaggtaact tcaaccttga tatctttgat accctcgatt tgtttcagac
    10621 ctgccacaat ttcaataggc aggctttcgg cgcaatcaca ggcagtatcg gtgaaggtca
    10681 tgacaatctt gcagagcccc gtttcatcca gattgatttc ataaatcaga cctagattgt
    10741 aaacatccaa ttccacatct gtatcaaaaa ctttctctag tttttcgata atttggtctt
    10801 gcaaggccaa agcacggtca ttgattttga tatcgtctct catagcagtc cctccacgtg
    10861 ataaatatcc tctattttct cataattctg acaatttggc aagtttttga tgaattttct
    10921 gaaaaatatg ataaaatgaa gaaaatacgg aatcaagggg aagtctatgg agcagattgg
    10981 aaaagtcttt agacaattac gagagtcaag aaatatctca ctgagacaag caaccggagg
    11041 acaattttcg ccgtctatgt tgtcccgttt tgaaacaggt cagagtgagc tttcggtgga
    11101 aaagtttcta tttgctctgg aaaatatatc tgccagtgtg gaggagatcc tctttctggc
    11161 gagaggtttc cagtatgata cagattctga gttgagaaaa gaaattacag atgtcttgga
    11221 accaaagaat atagcacctc ttgaggactt atatcgcagg gagtatcaaa agcatgccca
    11281 ttctcacaac aaacagaaac atattctaaa tgccattatt atcaagtctt atatgaagag
    11341 catggatgaa agggtagagt taacagcaga ggaaggaaaa gtccttcatg attatttgtt
    11401 ttctaccgag atctggggaa tctatgaact caatttattt tcagtcagtt ctccattttt
    11461 atctgtttct ctttttacta gatatgtacg agaaatggta cgtaaatctg attttctaat
    11521 ggaaatgtct ggcaatcgaa acctttttca tactatacta ttgaatggct ttttagctag
    11581 tattgagtgt gaagaattta ccaatgccta ttattttaaa cgtgttatcg aagagcattt
    11641 ctacaaggaa aatgagacct atttccgaat tgtttatctg tgggcagaag gtctccttga
    11701 tagcaagcaa ggtagagtca aggaaggcca gaaaaagatg gaggatgctg tccgtatttt
    11761 tgagatgctt ggctgtaata aatctgccga atactataga aatacgactg aatgttgaat
    11821 atctgcaaac caagaaaaaa tttgaagcga tagaactatt gccctctctc aggtcattac
    11881 aaaagttcta tcgtttcttt ttgctcattt tatttgttgc atatattcaa gagttctccc
    11941 tctcaaattt ctaagtgcta tactatagtc atacttcata tagaggttcg aacaagaagg
    12001 gagattatct atgaaactat tgtttagaaa tccagcttat agaattttga ttttatcacg
    12061 cttcttcaat gcttttggtg cttcgatttt caacctggtc tttatcgtct atgcatcgac
    12121 cttgtcacaa gcatcttttg ctgttgctat ggcgaatatt gtcatgattc ttccgaccct
    12181 ctttacagtt tttgtaggga ttcgggcaga ttacacgagg gacaaggtca aatggatggt
    12241 ctatagcggt ttgtttcagg cggttctatt ttttctagca gccctagttg ttcagcaagc
    12301 tagtctcttt gccttttcta gcctgtgttt gatcaatgtc attagtgata tcatcagtga
    12361 ttttgcaggt ggcctgcgta tgcctcttat taaggaaaaa gtagctgaag atgatttgat
    12421 ggaggcttat tctttttcac agttcatcac ctatatttca gctattggtg gtcaagcttt
    12481 cggagtctgg ctcttagctc tatcggtcaa caatttttct ctcgttgcgg gaatcaatgc
    12541 ctgctttttc ctagtatcag ccactatcct ctttttagga aaaagcaaat tgagcctgtc
    12601 aatgtcatct gctgatggtg aaaacttaaa aaatgagaag ctttctatca aagaccagtt
    12661 cctaacaatt taccgaaatt tacgtctcgt ttttcttaaa agtggacaga aaaactttgg
    12721 ttttatgctc tttgctgtct tgcttattaa ttccttgggt ggcgctttgg gtggaattta
    12781 taatatcttc tttttgagcc attctctctt gaatttttct tatacagagg cactatttat
    12841 caatcaattc tgtgttttag tagcaatcat catcagtagc cttacgggca atgcttattt
    12901 tgggaagcag tccttgccta gattgatgat gtgggcgacc gtaggactta gtctagttgg
    12961 tttggctaat ttattcaatc aagtcgtgct tggtttgcta tttctcttct ttactctgta
    13021 tgtgtctggt aaagttcaac caaagattag tgccatgctc atgaaaaatc tagctccaga
    13081 ggttctagct cgtactagta attttttagg tctattgttt accttatcca tacctgtggg
    13141 aacagcttgt ttttcactag tagccgtatg gaacatgcag ttgacttgga tgctatttgt
    13201 tggtctttcc ttgctagcta tttttttaac aattcttaat ctcaaaaatg atatctaaat
    13261 cctaattttt ttcttactgt tttaatccct ctatttatgg taaaataaga ctattaagtt
    13321 taaagaggat tccctatgaa attacaaaaa ccaaaaggaa cgcaggatat tttacctgct
    13381 gagtctgcta agtggcagta cgttgagggc tttgcccgtg agattttcaa gcgctataac
    13441 tatgcagaag tgcgcacgcc tatttttgag cattacgagg ttatcagccg ctctgtcgga
    13501 gatacaacgg atatcgtaac caaggaaatg tacgattttt atgacaaggg tgaccgtcat
    13561 attaccctcc gtccagaagg aactgcgccc gttgtccgtt cctatgtgga aaataaactc
    13621 ttcgccccag aagtgcaaaa gccaagcaag ttctactata tgggacctat gttccgttat
    13681 gagcgtccac aggcagggcg cttgcgccaa ttccaccaga ttggtgttga gtgttttggc
    13741 tctagcaatc cagctaccga tgtggaaaca atcgttatgg cagcccattt tttgaaggaa
    13801 atcggtattc aaggtgtcaa attgcacctc aacactcttg gaaatcctga gagccgtgca
    13861 gcctaccgcc aagccttgat tgactatttg acaccgctca aggagacctt gtctaaggat
    13921 agccaacgtc gcttggagga aaatcctctt cgtgtcttgg actctaagga aaaagaagac
    13981 aaggtggcag tagagaatgc gccgtctatc ttggactttc ttgatgaaga aagccaagct
    14041 cattttgatg ctgtgcgtca gatgttggaa aatcttggag tagattacat catcgatacc
    14101 aatatggtgc gtggtctgga ctactacaac cacaccattt tcgagtttat cacagagatt
    14161 gagggcaatg acttgacagt ctgtgcgggt ggtcgctacg atggtttggt tgcttacttt
    14221 ggaggccctg aaactgctgg atttggtttt gggcttggtg tagagcgtct gcttctcatc
    14281 cttgaaaaac aaggcgtggc cctccctatc gaaaatgcct tagatgtcta tatcgcagtc
    14341 ttgggtgatg gagcaaatgt caaagcccta gaactagtcc aagcccttcg ccaacaaggt
    14401 ttcaaagcag agcgtgatta cctcaaccgt aagctcaaag ctcagttcaa gtcagccgat
    14461 gtctttgcga ctaagaccct catcaccctg ggagagagcg aagtcgaaag cggacaagtg
    14521 acggtcaaga acaaccaaac ccgagaagaa gtgcaagtgt cacttgagac aatcagccaa
    14581 aacttttcag aaatctttga aaaactagga ttttatactc aataaaaatc aaagagcaaa
    14641 ctaggaagct agccgcagat tgctcaaaac actgttttga agttatggat agaactgacg
    14701 aagtcagctc aaaacatggt tttgaggttg tagatgaaac tgacgaagtc agtaaccata
    14761 cctacggcaa ggtgaagctg acgtggtttg aagagatttt agaagagtat taatgataga
    14821 taaagtggtc aggaacttac tcctgacctt tttcttttgc aaaatgacaa aaatcataaa
    14881 ctttttgaca actataattg tcaaaaagaa aaagatatgt tacaatgaat tcaagttaag
    14941 aaataggaag cagaaaggag ttataatgtg ggtactagga tttatactat ttatgatttt
    15001 cttttattct aataattcta aaaaaatcaa gaaactagag aataaaatca aaaaacttga
    15061 gcgaaaagag aaaggaaacg cagaaatgtc gagattatta caagaaatga ttggaaagga
    15121 accaattata acgggagtgt atattgggcc agataactgg gaagttgtgg atgttgatga
    15181 ggaatgggtc aaactacgta gtgttgataa tacgggaaaa gaaaaattca agttgcaacg
    15241 tattgaagat atccaaaccg ttgaatttga cggagagtag gtgtgtaacg tgcaactaaa
    15301 aaatcgtcta aaagagcttc gagctcgcga tggtctcaat caaaccgacc tagccaaact
    15361 ggcaggggtt tccagacaga ccattagcct actagaacgg gatgagtaca ccccatccat
    15421 tatcattgcc ctgaaaatat ctcaaatttt caacgaaaca gtcgaatcgg tatttcgttt
    15481 ggaggaggac gagtgatgaa caagtataaa gtgatttatt atgtagtggt catagcttta
    15541 ttagtcagcg tatttctact gattgggatg gacctaagct ggtttaatcc ctatcaaagc
    15601 gaccaatttg tttgggtcta ctttgctctc atcccagtaa ctgaatggat tgaaaagaaa
    15661 tccaaaaatc tagcaagtga aaaaggagaa tgaatatgaa aaagaaacgt agattgttat
    15721 ttttgatgtc tattgtcttg ggggggttct tgggcatgtt tgtagggatg tttaaggcac
    15781 gtgtcgaatc ccacgaaatt attttagatg taaaagcctt gatgccatgg atatcagcta
    15841 tttgtttact gataggtttc attagtatgt ttttgacttt caatttctta aagaaaagca
    15901 gaaaatttca ttccttgtat caagaggaaa tggatgacga tctgaatgaa acctattatg
    15961 tgcaaatgta tcggaatctt gagtttggaa ccattgcttt taatattata ggtgtagcga
    16021 ttccattggc tatttttatt tcattaagtg aggtgattat attgcataca aaccctcaaa
    16081 catttttcct ttctttctta ctctttgtgg tattcttagt cgctcaaaaa tctcttttta
    16141 aaaccattgc gattgttcgt cagtttgatt tggaattttt cgctacacca aaggatgtct
    16201 tgaactatat aaattcttat gatgaagggg agcgtcaggc taatttggaa cagagttttc
    16261 gaattttatt ccaattacac caatatgtct taccagcctt atatattttt cttattatca
    16321 tttctttctt gacaggagag attcagttac tagctttctt gcttgtagga gccatccatg
    16381 tttatatcaa tgtgatgcag ttacctatgg taaaacgtta tttcaaataa aggagttatc
    16441 tatgaaatta cttaaaaacc ttggctggat tcttctagcc cttctatcct ttttatttat
    16501 ctatggcttt attcaggggc tcgcgactgc gtcgcttgct ttaggcgctt caccctatgc
    16561 tgttactcta ctctatgtgg ccttggctgg agtatatgtg tacggcattt acaaatggta
    16621 tcagaaggct cctgttcata ttgagaagag cggctttaat cgatttattt ggcttcctgt
    16681 cttggtttgg ttcttatctc tggtcgttca attcttcttg ccagatgatc cttcagtaaa
    16741 tcagcaaata gcgacagact tgaccttgtc tcaaccactt ttctcattct ttgctgtggt
    16801 tatttttgct cctttgacgg aagagattgt ttttagaggg atgttagcac gctatctctt
    16861 tcctaagcag gacaatagta aacgaaccct gatttttctt ctggtatcta gtcttctatt
    16921 tgccttgatt cattttccag gtgatgtgca acaatttttt gtctatttta gccttggttt
    16981 tagtttgggt ttggcttacg ttagcagaaa aggtctggtc tacagtattt ctcttcacgc
    17041 tttgaataat ttagtcggct ttttgatgat tctcatgcta taatagagtc aggaggtcac
    17101 atgaaacgag taattttatt agcagtgatt caggcagtcg ttctattttt catcattgga
    17161 gcgctagctt atgccttcaa aggcgatttc ttctataact atctagcagt tgtctttgct
    17221 cctattgcag gtgtactgcg ttttgggacg gcttacataa cggaaattgt cttgcctcga
    17281 aaggcagccg aaatcgctga aaagcgtaaa gcaggcaaaa attcaaaata aaagagtccg
    17341 gtgaagttca tcggattttt gtattatact caatgaaaat caaagagcaa actaggaagc
    17401 tagccgcagg ttgctcaaaa cactgttttg aggttgtgga tagaactgac gaagtcagct
    17461 caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt cagtaaccat acctacggta
    17521 aggcgacgct gacgtggctt gaagagattt tcgaagagta ttagcgctaa tttttagggc
    17581 tttcacctga cttttaaaga ctggcaaact tttctgatga ttttcatgaa gagcctgcgc
    17641 ttttatggta aaatagtaac agaataaaag aggagagaaa taatgaaacg tagtatgtat
    17701 gctggtcgtg ttcgtgagga acacatcgga caagaaataa ccttgaaagg atgggttggc
    17761 cgtcgtcgtg accttggtgg tttgatcttt atcgatcttc gtgaccgtga aggaatcatg
    17821 cagttggtta tcaaccctga aaaagtatct gcagaggtta tggcaacagc tgaaagcctt
    17881 cgtagcgaat ttgttattga ggtgactggt caggtcgctg cgcgtgagca agccaatgat
    17941 aagttgccaa ctggtgcggt tgagttaaac gtgacagctc ttattgtgct taacacagct
    18001 aagacaacac catttgagat taaggatggc attgaggcaa atgacgatac acgtttgcgt
    18061 taccgttacc ttgaccttcg tcgtccagaa atgttggaaa atcttaaact tcgtgccaag
    18121 gtgacccact ctatccgcaa ctacttggat gagttggagt ttatcgacgt ggagacacca
    18181 ttcctttcta agtcaacgcc tgaaggggcg cgtgattatt tagtgccgtc tcgtgttaat
    18241 aaggggcatt tttacgctct tcctcaaagt ccacaaatca cgaaacagct cttgatgaat
    18301 gctggttttg accgttacta ccaaatcgtt aaatgtttcc gtgacgagga cttgcgtgga
    18361 gaccgccagc ctgaatttac tcaggtcgac ttggaaacgt ccttccttac tgagcaagaa
    18421 atccaagata ttacagaaag cttgatcgcg cgcgtgatga aggaaacaaa aggcatcgaa
    18481 gtaacgctac cattccctcg tatgaaatac gatgatgcta tggctcttta cggttctgac
    18541 aagccagata ctcgttttga catgttgctt caggacttga cagaagtggt ccgaggtgta
    18601 gactttaaag tcttttcaga agcacctgct gtaaaagcga ttgtggtcac aggagctgcg
    18661 gacaactatt cacgtaaaga catcgacaag atgacggaag tagccaaaca gtatggtgcc
    18721 aaaggtcttg cttgggtcaa ggtggttgat ggagaattaa acggaccagt tgccaagttc
    18781 ttgactggta tccaagaaga attgacaaca gcgcttgttc ttgaagataa ggacttggtt
    18841 ctctttgtgg cggatacgct tgaagtggct aatgcaacac tgggtgccct tcgtggacgt
    18901 attgctaaag agcttggctt gattgataat gataagttca acttcctttg ggtggttgac
    18961 tggccgatgt ttgaatggtc tgaagaagaa ggccgctaca tgagcgccca ccatcctttc
    19021 acacttccac aggaagagac tgctcatgaa ttagaaggtg atttggctaa ggttcgtgcc
    19081 attgcttacg atatcgtctt gaacggttat gagcttggtg gtggtagcct tcgtatcaac
    19141 caaaaagacc ttcaagaacg catgttcaag gctcttggtt tctcaactga agaagccaat
    19201 gaccagtttg gtttccttct tgaagccatg gactatggtt tcccaccaca cggtggtttg
    19261 gctatcgggc ttgaccgttt tgtcatgttg cttgctggag aagaaaatat ccgtgaagtc
    19321 attgcctttc ctaagaacaa caaggcaact gacccaatga cacaagctcc atcaacagtc
    19381 gctctcaaac aactagagga actcagctta caagtagaag aagatgaaac aaacaaaacg
    19441 aattaagcgg tggcgctatt atctgcgccg ctttgcttat cagataaaaa ttttacgtgt
    19501 cttacaaagt atctctcgag aaaagtatga tgagaagatt tcggcctctc tggtctatgg
    19561 ttttttatca gcagtagcag ttaatttctt tttccaacca gggcatgtgt attcgagtgg
    19621 tgcaacaggt ctggcacaga ttatctctgc cttgagtaat cactggtttg gttttcatat
    19681 tccgatttcg ctaaccttct acgccattaa cttccctttg atggtcttag cttggtatca
    19741 gattggccat aagttcaccg tctttacctt tatcacggta tctatgagtt ccttctttat
    19801 ccagtttgtc cctgtggcaa ccttgacgga ggatcccatt atcaatgccc tttttggggg
    19861 tgttgttatg ggtttgggga ttggttttgc tcttcgaaac aatatctcca gtggtgggac
    19921 ggatatcgtc agcctgacta ttcgcaagaa aacgggtaag aatgttggta gtatttcttt
    19981 cttggtaaat ggaactatca tgctgatagc aggtttgacc tttggttgga aatacgctct
    20041 ttattctatg attaccatct ttgtctctag ccgtgtgaca gacgcagtct ttactaagca
    20101 aaagcgtatg caggccatga ttgtgacaaa tcatccagag aaggtaattg aaaaaatcca
    20161 taaaaaattg caccgcggag caaccatgat ccatgatgca gaaggaacct ataatcacga
    20221 gagaaaggca gttttaatca ctgtcattac acgtgcagag tttaatgaat ttaaacagat
    20281 tatgacacaa gtggatccaa gctcctttgt ctctgtctcg gaaaatgttc atattctagg
    20341 aagatttgtt gagatagata attagtgatt aatactcttc gaaaatctct tcaaaccacg
    20401 tcagcgtcgc cttaccgtat gtatgttact gacttcgtca gttctatctg caacctcaaa
    20461 accatgtttt gagctgactt cgtcagtttc atctacaacc tcaaaaccat gttttgagct
    20521 gactccgtca gtttcatcta caacctcaaa accatgtttt gagctgactt cgtcagttct
    20581 atccacaacc tcaaaacagt gttttgagca acctgtggct agcttcctag tttgcacttt
    20641 gattttcatt gagtataaaa agatcttggg taacaactca atttcagtag aaaaggaagt
    20701 aaatcttccc acaataaaac gcatagtatc aagttttttc aatacctgat agtatgcgtt
    20761 tttgctttta acgacttttt gcccagtctc ttatttttcg ataattttgt gggcgatcaa
    20821 ttgacggtaa caaatttgtt tattgttttt attatcatta ataatctgga gaatagtttc
    20881 aagggaaaca cgaccaagct ctaaactatt gatatcgaca taggctgcca agttgagctt
    20941 gggattaacc gagtcaaagc tgagaacagg gacatccagc tggtgtttgg caatatagtt
    21001 acaaacacct tcagctagga ggctatcggt tgtgatgata gcatcaattt gtggatcgtg
    21061 cttgaataat cgcttgctaa atttatagcc cttttcttcc agaaactcgt cggcaaagta
    21121 gatgcgattg ttgtcagtgg taagtttgta atgtttaagc gcctgttcat agcctgttaa
    21181 acggtctttg gtcacgaaga gctttttact tcctccgata aaggcaatgc gtttgcagcc
    21241 ttttttgatg aaatattcag tcgcatcaaa accagcttga acattgtcgt tgtcgacaag
    21301 tgggatgaaa ggagatagag atttacctaa gataaggaag gggaactgtt cttctgcgac
    21361 gagttttacg agagggtctt cttcttgggc atagagaaag attagcccat ctacacgctt
    21421 gccgtagacc atttgtgaaa tagcgttgag acgctccttc tcatctttcc ctgttgctat
    21481 ctgaatggca tagtggtttt cagatgcgac ttgagagatg ccacgtagaa ccgatggaaa
    21541 gaaaggattc tggtagaagg cgtctgagtc atcaggaaga actaatccga taacctgagt
    21601 atagctgctt accaagctac gagcgttgag gtttgggtgg tagttgagtt ccttcatagc
    21661 tttgcgaacg cgtttttttg tttcgtcgct aatggttgat ttattttgaa taacacgggt
    21721 tacggttgaa ggcgaaacac cagcagcctt ggccacgtct ttaatcgtaa cgggcataaa
    21781 aatctcctat ttatggtaat ttggatcacg gaaatgtgtt ttataaaaga tagtgaccag
    21841 atacagaaca aaaagaatat tttgtacagt aatcagggtt gtcatatttt ggccaaataa
    21901 tcccaaaata agtgtaatca gagtcggcaa tcctaaacag ttcaagataa agtgatagca
    21961 ctctttaaag gttctaaatg aaaagaggcg tgatttctta gtgatataaa ggagaagact
    22021 agctcctaga gagacgataa agaaattcaa accaaagagg aagctcgcac cgagaactag
    22081 gaagaggctg atatagacac gattttgttg gtaccagtct ttagaaattg cttgggtcaa
    22141 gctgtctttg cttttgaaac tctcagtctg aatggctcgg taagagatgc gggtcagttc
    22201 cttgctttcc ttgctgatga ctagctcatt tgtatcgaaa tgcagttgca agtccttagg
    22261 taattccttg atttgacttg gaccaatcac aacagaaggg gcttgactag ctgttccagt
    22321 ataagttaat gtgccatcga caattgtagc atgttcagag agatcctgga caacctcatt
    22381 tgtcagaggt tcatagacat tatcgataaa agtttctagc ggataggtct cctgggagct
    22441 gttttggata gcaatgggta ccatagacaa gctgataagg aagatactgg taaagagaag
    22501 ttgaaaccag ttgagctcga aacgtttgga caggggctta cgaaaccccc aaatacttga
    22561 aaaataggaa aatggatatg gaagcatagg tatctttcta aaaggtgttt tctatatgag
    22621 tattattata tagagaaatg cgctttattt caagtctagg gggtaaattg cttgctacaa
    22681 ggatattatt tacagtgaca atcgctaata gtcaatgaaa atcaaagtgc aaaccaggaa
    22741 gctagctgca ggttgctcaa agcacaactt tgaggttgga gataaagctg acgtggcttg
    22801 aagagatttt cgaagagtat aaaatgaaaa agggtggcgg ggataaatta tcccttgtcg
    22861 ccaccacttg taagtcctga aacaaagttc ttttgtagga agaagaagag aatacagatt
    22921 ggaagggcga tgaggatagc acctgctgag aagtaggcaa tcttcaagtt tttcgcattg
    22981 ttaacgaagg tttggagacc tacggcaaca gtaaagtatt ctttctcacg aagcaagaaa
    23041 ctagagagga tgtagtcccc gaaaggtccc atgaaggccc agagagcttg tacggcaacc
    23101 attgggcgaa caagtggtag aacaatttgc cagaagcggc ggaagtgtcc tgcaccgtct
    23161 agttttgcag attcgtctaa agacattggc actgtatcga agtagccttt catgagccaa
    23221 gcattcatcg ggataccacc accaacgtag aggaagatga ggaaccagtt gtggttaagg
    23281 gcgttcaaca taagcgccat aacgaagaag gctgtcaaag cggccatagt tggcaccatt
    23341 tggatgatca agaagaagac caaactttgt ttacgagcca agaagttgta acggctgtaa
    23401 gcataaccag caagtacgat gatacttgtt tgaacagcca tggtaattaa ggcgataatc
    23461 aaagtgttga ggtaccaagt accgtacaag gtttcagtga agaggccttt aaagttatca
    23521 aaattgaggt cgatattagt atctagttta aaggctgaga cgttacctgc tttaaaggct
    23581 gacatgatgg taatcaacag tggatagata attacaattg atagaccaat caggtaaagg
    23641 taagtaaggc tttgagtcag tctacgtttg agtttaattg agttattcat cttagacgtc
    23701 ctccatatca aatgcgtgta gtttcttgaa tgcgatcata gagattgaga tgacaatgat
    23761 agagataatc aaggtaacag ctgccgccat tgagtattga ggagatgtac ctgttgtcaa
    23821 acggtagatc catgagatca agatatcggt tgaaccagct ccacctccga cactaccagg
    23881 tcctccacca ttgaagaggt acatgataga gaagttgtta aagttgaagg tgtattggct
    23941 aatcaaagta ggtgccgcaa cagccaaaat cattgggaaa gtgatgttgc ggaatttttg
    24001 ccaagcgttg gcaccgtcaa tataagctgc ttcgtaaagg tcgttaggaa tagattgcaa
    24061 gatacccaaa gtcaaaacgt agatgtatgg gaatccgagc caaccttgca tcataatcaa
    24121 ggcaatctta gtccaagttg ggtctgtttt ccaaggaata agagctccat caaggaaagg
    24181 aaggaattta gccaagattg gcaatacttg agtgttgata gcaccgacac tatcgttaaa
    24241 catgtttgag aatgtcaaga tagtgatgaa ggctgggaca gcccaaggaa gaaggaaaat
    24301 aacaccaaag atacgttttc ctttgataaa tggttggttg gcaatgatag ctgtgaagat
    24361 accaattacg atttgtaaag tagaagctgc caaagcccaa atgatagtcc aagaaagaac
    24421 agaaccaaag gcagaacgga aggtactcaa gctccaaatg tttgtaaagt tggtcaaacc
    24481 aacccagtcc aacaacttgt ttggtggcaa gtgttggaag tcgtagttgg taaaggcgat
    24541 catcaaggtt acgataactg ggaagataat cgcgaaggtc atggcaacat aagatggaat
    24601 gatcaagagg taagggaagc cattttcata aatccctttg atcatgtctt tgagtgtgcg
    24661 tggaactgga attccattgt taatgcgttt tgcaatcgta tgtgcatctt tgatatttga
    24721 gaaataaaag agtacataaa cgattacaaa gattagatgg aaggcaccac gaatcagcat
    24781 aaagagggaa ttatcacgac ctggtttgtc accaagagtg atgaggttgc tcaattcagg
    24841 ggttgcaagt gctaggaagt aaaggacaaa tacgatggtt acaccaagga agataaaacc
    24901 tttggctttt tgtttattgt aaatctgtcc taacccagga atgatagaca gcagggctgc
    24961 tttactaggt tgttgctttt ccatattaac tcctttcata ggatactact tttttataag
    25021 aaagctaaat tatttgtgtc tctattgata aattcaaagg gggatttgat ttccaccccc
    25081 cttgaacaaa ttttttattc accaaatttt tgtttgattg tttctttgat caatgttaca
    25141 gcatcgttag cagctgtttt agcatctttt tgaccactta cagcatcaaa gagcatattt
    25201 ttcgctggat cccaaactgc agacatttga gagatgtttg gcagtggttg agtgttcttg
    25261 aactgtttga taacagctgt tgtcaactca tcgtttttac cttcagcgta tgaacgagcc
    25321 tcagtattag ctgggatttc gttagtctta tcatataata ctttttgttg ttcagttgca
    25381 acaaggaagt ctacaaattt ttgagaagct tcaaggttct taacggcttg aggaatgacc
    25441 caagctttac caccaccgaa tgcagcatat tcttttccat ttggaagagt tgggatagtt
    25501 gcaactccgt agtttacttt agcatcttta aaggcttgag ctttccaagg tccgtcgatg
    25561 atagcagctg ttttaccttc ttggaattga gtttggatta agtttccagc accttctgta
    25621 tcttgcatac ctttaggcca tttttcgtac caagatttag cgtagttgat acctacgata
    25681 gaaccgtcgt ttgcaagacc gatgtcttta gcgtctttac cgttttggcc aaagacgtaa
    25741 gcaccgttac cggcaagaag tccatatgta tagtagaagt ttgtccagtc agctaggaag
    25801 gcagtagttt taccatcttc accagcgaat gcgtatttgc tatctttagc aaggttttcc
    25861 aagtcagcaa atgtttttgg agcatctttc accaagtctt tgttgtagta cataacaagt
    25921 gactcgataa cggcaggagc accgtaaact ttaccattag cagctgttac aagagattta
    25981 gttgtgtcgt ctgttttagc accatcgctc aatttcactt ctgaaagttg tccgtcagaa
    26041 ccaaggctac ctacacggtc gtatggagcc atcataacat cagggacatt accagattgg
    26101 ttgtcaagag aaagtttatc aagacctcct agagcatcac cagttttaag agtgactttt
    26161 actccagctt ctttttcata agctttagca acctcttcaa tatagctctt atatccctcg
    26221 tctacatata cagtgagttc tttgacttca gatgaaccag aatcagcagg cttatcagca
    26281 gttttgcttc cgcaagctac caaaagcaag ctagcaagtg taacagttcc aagcaccgca
    26341 gcgctcttca taaatttaga tgacatagtg tattcctccc aaagaatagc aagttttatt
    26401 gataaggaaa cgcaaacgtt ttcctttatg agcttagtat agcacaaata gaaaacggtt
    26461 gcaagtattt tttgtaaaaa ttttaaaaaa tttttaagct tgatttgata gcataatttt
    26521 gcattttaat agaagaaaag tatgaaatag ataagaatac agtattttta ataaaaatat
    26581 atggaatatg tctaaagagg gaaaccagga ggggctacct ccctggttct aatccctatc
    26641 tattttctat ggacgtttgt gctttgttac atataaattc aagctcccta aggaggtttt
    26701 gtactttgta gactgtctcg tgagagtcaa accttaggat tagatagttt taagttatct
    26761 ttgctaaaat gagttagtct ccttaaaaat aatcaaaaaa gttttttaaa aacgcttgca
    26821 attatgcttg aaaaggagta tacttataag taacgcaaac gtttgcgtct gcaaaatacg
    26881 caacgttcca ttattttaac acacgaggtg ctattatgaa aaaacgtcaa agtggtgtgt
    26941 tgatgcacat ctcttctctt ccaggagctt acggaatcgg atcatttggt caaagtgctt
    27001 acgacttcgt tgatttcttg gtccgtacaa aacaacgtta ctggcaaatc cttccattag
    27061 gagcaactag ttacggggat tctccttacc aatctttctc agccttcgca ggaaacactc
    27121 attttatcga tttagatatc ttggtggagc aaggtttgtt ggaagcaagt gaccttgaag
    27181 gagttgactt tggtagcgat gcgtctgaag ttgactatgc taaaatctac tatgcacgtc
    27241 gtcctctttt agaaaaagcg gtgaaacgtt tctttgaagt cggagatgtt aaagattttg
    27301 agaaatttgc tcaagacaac caatcatggc ttgagctctt tgctgagtat atggctatca
    27361 aagagtattt tgacaatctt gcttggactg aatggccaga tgcagatgct cgtgctcgta
    27421 aagcttcagc acttgaaagc tatcgtgagc aattggcaga caagttggtt taccaccgtg
    27481 tgactcaata cttcttcttc caacaatggt tgaaattgaa agcttacgct aacgacaacc
    27541 acatcgaaat cgttggggac atgccaatct acgtagcgga agattcaagt gatatgtggg
    27601 caaatccaca tctcttcaaa acagatgtca atggtaaggc tacttgtatc gcaggatgcc
    27661 caccagatga gttttctgta actggtcagc tttggggtaa cccaatctat gactgggaag
    27721 caatggacaa agacggctac aaatggtgga ttgaacgctt gcgtgaaagc ttcaaaatct
    27781 acgatatcgt tcgtatcgac cacttccgtg gcttcgaatc ttactgggaa atccctgctg
    27841 gttccgatac agcagcacct ggtgagtggg tgaaaggtcc aggctacaag ctttttgcag
    27901 ccgttaagga agaacttggt gagctaaaca tcatcgcaga agaccttggc ttcatgacag
    27961 atgaagtgat cgaattgcgt gaacgtactg gcttcccagg aatgaagatt cttcaatttg
    28021 ccttcaaccc agaagacgaa agcattgata gcccacactt ggcacctgct aactcagtta
    28081 tgtacacagg aacacacgat aacaatacgg ttcttggttg gtaccgtaac gagattgatg
    28141 atgcgactcg tgagtacatg gctcgttaca cgaaccgtaa agaatacgaa acagtggtac
    28201 acgctatgct tcgtacagta ttttcatcag ttagctttat ggcaattgca actatgcaag
    28261 atttactaga attggatgag gcagctcgta tgaacttccc atctaccctt ggtggaaact
    28321 ggtcttggcg tatgactgaa gatcaattga caccagctgt cgaggaaggt ttgcttgact
    28381 tgacaacaat ttatcgccga attaatgaaa atttggtaga tttaaagaaa taagacaata
    28441 atcaggagac aactaaacat gttatcacta caagaatttg tacaaaatcg ttacaataaa
    28501 accattgcag aatgtagcaa tgaagagctt taccttgctc ttcttaacta cagcaagctt
    28561 gcaagcagcc aaaaaccagt caacactggt aagaaaaaag tttactacat ctcagctgag
    28621 ttcttgattg gtaaactctt gtcaaacaac ttgattaacc ttggtcttta cgacgatgtt
    28681 aaaaaagaac ttgcagctgc aggtaaagac ttgatcgaag ttgaagaagt tgaattggaa
    28741 ccatctcttg gtaatggtgg tttgggacgt ttggctgcct gctttatcga ctcaattgct
    28801 actcttggtt tgaatggtga cggtgttggt cttaactacc actttggtct tttccaacaa
    28861 gttcttaaaa acaaccaaca agaaacaatt ccaaatgcat ggttgacaga gcaaaactgg
    28921 ttggttcgct caagccgtag ctaccaagta ccatttgcag actttacttt gacatcaact
    28981 ctttacgata ttgatgttac tggttatgaa acagcgacta aaaaccgctt gcgtttgttt
    29041 gacttggatt cagttgattc ttctattatt aaagatggta tcaactttga caagacagat
    29101 atcgctcgca acttaactct cttcctttac ccagatgata gtgaccgtca aggtgaattg
    29161 ctccgtatct tccaacaata cttcatggtt tcaaacggtg cgcaattgat catcgacgaa
    29221 gcaatcgaaa aaggaagcaa cttgcatgac cttgctgact acgcagttgt ccaaatcaac
    29281 gatactcacc catcaatggt gattcctgaa ttgattcgtc ttttgactgc acgtggtatc
    29341 gagcttgacg aagcaatctc aattgttcgt agcatgactg cctacactaa ccacacaatc
    29401 cttgctgaag cgcttgaaaa atggcctctt gaattcttgc aagaagtggt tcctcacttg
    29461 gtaccaatca tcgaagaatt ggaccgtcgt gtgaaggcag agtacaaaga tccagctgtt
    29521 caaatcatcg atgagagcgg acgtgttcac atggctcaca tggatatcca ctacggatac
    29581 agtgttaacg gggttgcagc acttcatact gaaatcttga aaaattctga gttgaaagcc
    29641 ttctacgacc tttacccaga aaagttcaac aacaaaacaa acggtatcac tttccgtcgt
    29701 tggcttatgc atgctaaccc aagattgtct cactacttgg atgagattct tggagatggt
    29761 tggcaccatg aagcagatga gcttgaaaaa cttttgtctt atgaagacaa agcagctgtc
    29821 aaagaaaaat tggaaagcat caaggctcac aacaaacgta aattggctcg tcacttgaaa
    29881 gaacaccaag gtgtggaaat caatccaaat tctatctttg atatccaaat caaacgtctt
    29941 cacgagtaca aacgccaaca aatgaacgct ttgtacgtaa tccacaaata ccttgacatc
    30001 aaagctggta acatccctgc tcgtccaatc acaatcttct ttggtggtaa agcagctcca
    30061 gcctacacaa tcgctcaaga cattatccat ttaatccttt gcatgtcaga agttattgct
    30121 aacgatccag cagtagctcc acacttgcaa gtagttatgg ttgaaaacta caacgttact
    30181 gcagcaagtt tccttatccc agcatgtgat atctcagaac aaatctcact tgcttctaaa
    30241 gaagcttcag gtactggtaa catgaaattc atgttgaacg gagctttgac tcttggtact
    30301 atggacggag ctaacgtgga aatcgctgag ttggttggtg acgaaaacat ctacatcttt
    30361 ggtgaagatt cagaaactgt tatcgacctt tacgcaaaag cagcatataa atcaagcgaa
    30421 ttctacgctc gtgaagctat caaaccattg gttgacttca ttgttagcga tgcagttctt
    30481 gcagctggaa acaaagagcg cttggaacgt ctttacaatg aattgatcaa caaagactgg
    30541 ttcatgactc ttcttgactt ggaagactac atcaaagtca aagagcaaat gcttgctgac
    30601 tacgaagacc gtgacgcatg gttggataaa gtcatcgtta acatttctaa agcaggattc
    30661 ttctcatctg accgtacaat cgctcagtat aacgaagaca tctggcactt gaactaatac
    30721 tcttcgaaaa tctcttcaaa ccacgtcagc tttatctgca acctcaaagc ggtgctttga
    30781 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtata agatacaaat
    30841 ttatactaat acattttgta aaaaagcgag tttcgattga aattcgcttt tttaaatgct
    30901 gtggatttgg gtcaatcttg tctaaaaata gggaaatcct agatacagtg aaggctttaa
    30961 atgctggttt ttactgtctt tagccttata ttttttcgta gttggttacc tcatatctct
    31021 tgtattcgct tacataaagt attataatat aattgtagga aagaaggtgt ttttatgata
    31081 tacacactta aattggtgtt gtttattacc tttcttgtaa taagcttgtt acctgataag
    31141 atttttggaa aaaataaaaa aatttggaaa atagtttttg caatattgac ggcagtggca
    31201 gcattgtcat ttatgtacta agttatttta agaatgtagg gaaataaacc ctacattctt
    31261 tttagttttt tctgttttct aaattctatt tatccaagcg cttcaacatt tcttgcttct
    31321 tcgcttcaag ttctgcacgc ttttcttcga tttcggcatg ttttttctcg agttcagaac
    31381 aacttgcatc attgctaaat tcttttcgcc atcaggagat agggtgagtc gacatgtcta
    31441 ttactcaccc aaagcagtcc tacaaagcag gaattttctg ttactttttt ggaaatagta
    31501 acgtttatac agctttgaca cttcgtatca aagcgccaaa cacactccga gggatttaca
    31561 gaaagcagaa aaggaatgat ctggtataag atcattcctt ttctctcttt ttctttaagt
    31621 aattatatac aatgtacgac gaagtcgtca ttgcaatgct gatccaccac ctaaagggaa
    31681 ctttaaacaa gattgataag ataaagaata taaacaacga aaatacgtta tacccaatta
    31741 attttattgt atatctcatg attaaaagtt aatccttctg ttgttaggaa tggcatcatt
    31801 tttatcccat aattgtgcta aataagtccc cggtgataat aaattcatag cgaattctaa
    31861 agcaacatca tttacaaacc aactacctag atatctagaa attgctgaac gaatagcact
    31921 ttttgctgca tgttttcctt ttactttaat tagatttgca aggcctgcag tagttcctcc
    31981 taatgctaaa gctattgcag tatctaatag agcacccatt tgattaactg taataccttg
    32041 ccaagctgct ctaaatggag agtatgtagg tgggattgta taatcgcctt gtaattgtcg
    32101 gttaattact tctttgatcc attgttgtga gacgtctgga tgaaaagatt ggatttcgtt
    32161 tgcaagtgta ttgatttgtt cttctgttag agaagtgaca ggttgaagtt ccatatttgt
    32221 ttcaatttgt gatacttgtt cagaagcgta tacagctgaa acacttggaa tcgctgatac
    32281 aattaacaca attgacgtca aaaaaaccga aataaatttc attaatttgt tcatgaactt
    32341 ttctcctttt tatttgtatc tgcttacatt ttatcatata ctgttattat agtcaaaaaa
    32401 atatgctatt atgttaaaaa aatatttttc aaaatataaa tggacggatt tattttggat
    32461 tttatttgtt attttgacct gcctctatat tggtaaccat gatttgttta ctctcaatca
    32521 tcaagaattc tcttttcgtg gtagcgtttg gggtctggta ctggccttat atcacttact
    32581 attcattgat aagtttgtta tatcgaatcg aaaataaaga ttagagctat gcttgactgg
    32641 ctacttttag gattgatttt ggaggaagat tttgtctcta ttatttatta ttttaaattt
    32701 atttattttg tataagatct attctttgag gcgggaaaaa tcgaaatact tgatttatac
    32761 ggcctatatc atatttgggg taaatgtagt atatggtatt caatggttat taaaagaact
    32821 gatttcaact atttcccctt aatgtgtatg gaaactataa caaaacgcat aagattaagg
    32881 tttgtgtacc tgttcttata cgtttttgtc atattgaaga ttttcggtaa gttttctact
    32941 tttgcgaagt ctagtttata ctcaatgaaa atcaaagagt aaactagccg taggttgctc
    33001 aaagtacagc tttgaggttg cagataaaac tgacgaagtc agctcaaaac atggttttga
    33061 ggttgtagat gaaactgacg aagtcagctc aaaacatggt tttgaggttg tagatgaaac
    33121 tgacgaagtc agtaaccata cgtacggcaa ggcgacgttg acgtggtttg aagagtatta
    33181 gaatgctttc ccaaccaaaa tctctgcttc gatggtaatc tctgtcagtt ggctccagtc
    33241 aatcttgctc tggtcaacgt gaaagaggag aggagtcata ctgagtaggg cttggagttg
    33301 ttctgctgtg atagtcttag tcagagaggc agtttgacta gataggatgg taaagtgttc
    33361 ctggaaatgc tccttgatat cttggttaga atactccttg tttgtcagct ggtcctgtac
    33421 tctttgacgg atttctttga ggtgattttc agttgggata acctttatca agataccgtc
    33481 tttggataaa acgcgacgaa attctccata gttggcaggt gagaagatat caagcaggat
    33541 atccatgcta gcgtctttta taggaaggcg tgccaagtcg ccaacgaacc aattgactgc
    33601 ccagttgggt tcacttttag cagcgatttg gactgaatct ttggagatgt caaaggcata
    33661 gaaagttttt tcagagtgac tttcttgtag tttgcgagaa tagaatcctt caccacaacc
    33721 gatatccaaa attgttgtgg tagtttttga gcttgcaagc aagtcagata cagcatctaa
    33781 gatagcttgg taaaagccgg cttctaggat ttgttgacgg ttttgaaaat tttccttgtc
    33841 atagttagca gattgcttga tttgaggtgc tagattgaca tagccaaatt tcgccaagtc
    33901 aaaagaatga tggttgcagc acttgaaatt agtctctaac agagtcagat tttcttgaca
    33961 gataggacag gcaaaggcag tcgcagaagc aaaacgctga agtttgggct tgagatttgt
    34021 attcatagtt taagtgtatc aaaagaggca aatgaaagca actttaggaa taagtagatg
    34081 ggagattcag tagaaataaa actaattctc caatttatag aatgaaattg cttttatatc
    34141 taaattgcta tataataatg ataaggagga aataagtatg ttaaaagaag tattaaccgt
    34201 tgcaaaagtt gcgaaaaaat cttcattatt tttgggtggt gtcgcatttg gtacccttgg
    34261 tttgaaaatc ttagcaagta aggaagctaa aaaaggttat tctaaagctt tggctaaggc
    34321 ttacaagttg aaagacgagc tagatgcatc tgtttctgtc gtgaagcaac atggagacga
    34381 tgtcttgcaa gatgccaaat atttgtacga gcaagagaaa aaagaagagc aattagatag
    34441 ccttataggt gaataatatg tcttttaaag tgctacatag aggataccaa catatccgac
    34501 tatcatcttc tttttcactt accttggata ttcaagacta tcttcgttcc ttggcgagag
    34561 atgaaaaggg gattgagtct atccagtttt acatggatca acagcacttt actctacgca
    34621 taaaagaagg cttttctgta ttagataatg cagaagcctt tttaaaaaga attgataaag
    34681 ggaaagtttc tgagttgatg actcttccca ttcgtagaga agagagtgct tattctattg
    34741 tttcaggtgc agcggttaag cgtgtacttt ttcgtagttt tgtgccgtat cctattcgct
    34801 atatatggac ttgttatcag gctttgggtt atattagaga agcctatcaa acactagcgc
    34861 gtaaggaact aacgatggaa gtcttggact gttcggctat tttattgtct ttgtttatga
    34921 accaatccaa gacagctagc aatatcatgt ttatgcttga tttggggaat catttagatc
    34981 agtggtcctt gaaaaaaact gcaacagatt tagaacagag tcttcttgca aaagagagcg
    35041 atgtattcct agtacagggc gatacggttg ttagtatcaa gagttccgat gttcaaatag
    35101 gagatgtctt gatcttatct caaggaaatg aaattctgtt tgatggacaa gtagtttcag
    35161 gtttaggtat ggtcaacgaa agttccttga caggagagag ttttccagtt gaaaaaagag
    35221 agtctgattt ggtttgtgca aatacagtat tagaaactgg agagttacgc attcgtgtaa
    35281 cagataatca gatgaacagc cgtattttac agctgattga gttgatgaag aaatctgaag
    35341 aaaacaagaa aacgaaacaa cgctatttca tcaagatggc ggataaagtc gtcaaatata
    35401 atttcttggg ggctgggctg acttacctat tgacaggttc tttttctaag gctatttctt
    35461 tcctattggt cgatttctcc tgcgctttga aaatctctac tcctgtagct tatttgacag
    35521 ttatcaagga agggttgaac cgtgaaatgg tgattaagga tggagatgtt ctggagaaat
    35581 atctggaagt tgatactttc ttgtttgata agacaggaac aatcacaact agttatccta
    35641 tagttgaaaa ggtgttacct tttggagact atagtgagga agatattctc agaatcagtg
    35701 cctgtcttga ggaacacatt tatcatccta ttgctaatgc catcgtcaag caagctgaga
    35761 tagagggaat tgaacatgag gaaatgcatg ggaaactcca atatatcgca agcaagggga
    35821 tcaaatctca tatagatggc caaccagttc ttattgggaa ttatgtcttg atgcaggatg
    35881 agcagattca tatcagttca gaacaaaatg ctttaattga agagtacaag agtcactaca
    35941 atctcttatt cttggcttat caaaatgaat tgattggaat gttctgcatt catactcctt
    36001 tgagaaaaga agcaaaaaca gccttggata aacttaaggc acaggggaaa aaattgattc
    36061 tggcaacagg agacaccttg attaggacag aggaattagt caaagatttg ccctttgatc
    36121 aggtctatac agacttgaaa cctgatggga aatttgagtt agtagagaaa ctgcagaaag
    36181 caggtcacac tattttgatg gttggagatg gcttgaatga ctcagcggct ttaactctat
    36241 cagatatcgg tgtggtgatg aatgagagtg cagatatttc taagcagatg agtgatatct
    36301 tattgttaga taatcgtttg gatttcttcc aagagttgga ttcgttatca tcatctttgc
    36361 aaacactcat caagaaaaat attcaggata ccgttgtcgt aaatagtagt ttgattggct
    36421 ttggcttatt taattggttc agtccttcaa atctctctat cttacataat ctaacaacct
    36481 tgcgcattgt cctgcgtagc ctgtctatta aaaatagata gatgagagtt attaacagca
    36541 aaaaggagtt acctttctcg aggttaactc ctttgtttat agatagatgt tgaatagttt
    36601 agtaagtcaa tacaaagtat tttttcttcc cacgacggat aacagtcagt tcattttcta
    36661 acttatcagc gtcactcaag acatagtcaa ggtcttggat gcggtcgccg tttacgtaga
    36721 tggctccgtt ttggacgtct tcacgggctt ggcgttttga gttaactata ccagatgaga
    36781 cgagcagttc cacgatattg ttgttttcgt ctgcctgtac ttggtagttt ggcacaccac
    36841 gaagtccttg tttgagctct ttgacagaaa ggtttttgat gtttcctgca aagagttgct
    36901 cagtgatgtt aagtgcttct ttgtaggctt cttctccgtg aacaagtgta acaacttcac
    36961 gagccaagac tttttgagcc aagcgttcgt gtggcgctgc ttcaaattgt ttacgaatat
    37021 cttcaatctc atcaagtgac aagaaagtaa agattttcaa gaagcgaaca gtgtcagcgt
    37081 ccatcacgtt catccagaat tggtacattt cgtatggaga agtcttttcg ggattaagcc
    37141 agacggcatt tccttctgat ttaccaaatt tcttaccagt tgcatctgtg attagtggaa
    37201 cagtgataac gtgaccagtc ttgtccgcct tacgacgaag caattcggta ccagctgtca
    37261 tatttcccca ctggtcagaa ccaccgattt gaagagtgac attatggtct tggttaagga
    37321 cgaagaagtc gtacccttgc atgatttggt aagcgaactc agtgtaagaa attcctgttt
    37381 cgatccgttt tttaacagat tccttactca tcatgtagtt gaccgtgaag tattttccaa
    37441 tatcacggag gaagtcaatg aagctgatgc tgccaaacca gtcgtagttg ttgaccatga
    37501 cagccttgtt ttcgccattt tcaaagtcaa gaaaacgaga aagttgtcct tggatagact
    37561 tgacccagcc atctactgtg tcttttgttt ggagactacg ttcagcatct ttgaaggacg
    37621 gatctccgat gagacctgta gcaccgccaa cgagcgcata aggtttgtga cctgctagtt
    37681 gcaagcgacg acttgtcaag attgcgacaa ggtggcctag gtgaaggctg tcagcagttg
    37741 gatcgtagcc agtataataa gaaacttgac cttcttctag ggctttacgc aaagcttctt
    37801 catcagtcgt ttgaaatatc aaaccacgat cttttagctc atcaaaaatg tgcatgtgtc
    37861 ttttctcctt tttaaaatta ttgtttctac ctattgtatc acaaacttgg gcaatagcct
    37921 agcagaatag ggaagaaagt ggctatttta ttgaaaattt cccttttgtg gtataataga
    37981 tagagtgagg aaatccatgc aaaatcaatt aaatgaatta aaacgaaaaa tgctggaatt
    38041 tttccagcaa aaacaaaaaa ataaaaaatc agctagacct ggcaagaaag gttcaagtac
    38101 caaaaaatct aaaacattag ataagtcagc cattttccca gctattttac tgagtataaa
    38161 agccttattt aacttactct ttgtactcgg ttttctagga ggaatgttgg gagctgggat
    38221 tgctttggga tacggagtgg ccttatttga caaggttcgg gtgcctcaga cagaagaatt
    38281 ggtgaatcag gtcaaggaca tctcttctat ttcagagatt acctattcgg acgggacggt
    38341 gattgcttcc atagagagtg atttgttgcg cacttctatc tcatctgagc aaatttcgga
    38401 aaatctgaag aaggctatca ttgcgacaga agatgaacac tttaaagaac ataagggtgt
    38461 agtacccaag gcggtgattc gtgcgacctt ggggaaattt gtaggtttgg gttcctctag
    38521 tgggggttca accttgaccc agcaactaat taaacagcag gtggttgggg atgcgccgac
    38581 cttggctcgt aaggcggcag agattgtgga tgctcttgcc ttggaacgcg ccatgaataa
    38641 agatgagatt ttaacgacct atctcaatgt ggctcccttt ggccgaaata ataagggaca
    38701 gaatattgca ggggctcggc aagcagctga gggaattttc ggtgtagatg ccagtcagtt
    38761 gactgttcct caagcagcat ttttagcagg acttccacag agtcccatta cttactctcc
    38821 ttatgaaaat actggggagt tgaagagtga tgaagaccta gaaattggct taagacgggc
    38881 taaggcagtt ctttacagta tgtatcgtac aggtgcatta agcaaagacg agtattctca
    38941 gtacaaggat tatgacctta aacaggactt tttaccatcg ggcacggtta caggaatttc
    39001 acgagactat ttatacttta caactttggc agaagctcaa gaacgtatgt atgactatct
    39061 agctcagaga gacaatgtct ccgctaagga gttgaaaaat gaggcaactc agaagtttta
    39121 tcgagatttg gcagccaagg aaattgaaaa tggtggttat aagattacta ctaccataga
    39181 tcagaaaatt cattctgcca tgcaaagtgc ggttgctgat tatggctatc ttttagacga
    39241 tggaacaggt cgtgtagaag tagggaatgt cttgatggac aaccaaacag gtgctattct
    39301 aggctttgta ggtggtcgta attatcaaga aaatcaaaat aatcatgcct ttgataccaa
    39361 acgttcgcca gcttctacta ccaagccctt gctggcctac ggtattgcta ttgaccaggg
    39421 cttgatggga agtgaaacga ttctatctaa ctatccaaca aactttgcta atggcaatcc
    39481 gattatgtat gctaatagca agggaacagg aatgatgacc ttgggagaag ctctgaacta
    39541 ttcatggaat atccctgctt actggaccta tcgtatgctc cgtgaaaagg gtgttgatgt
    39601 caagggttat atggaaaaga tgggttacga gattcctgag tacggtattg agagcttgcc
    39661 aatgggtggt ggtattgaag tcacagttgc ccagcatacc aatggctatc agaccttagc
    39721 taataatgga gtttatcatc agaagcatgt gatttcaaag attgaagcag cagatggtag
    39781 agtggtgtat gagtatcagg ataaaccggt tcaagtctat tcaaaagcta ctgcgacgat
    39841 tatgcaggga ttgctacgag aagttctatc ctctcgtgtg acaacaacct tcaagtctaa
    39901 cctgacttct ttaaatccta ctctggctaa tgcagattgg attgggaaga ctggtacaac
    39961 caaccaagac gaaaatatgt ggctcatgct ttcgacacct agattaaccc taggtggctg
    40021 gattgggcat gatgataatc attcattgtc acgtagagca ggttattcta ataactctaa
    40081 ttacatggct catctagtaa atgcgattca gcaagcttcc ccaagcattt gggggaacga
    40141 gcgctttgct ttagatccta gtgtagtgaa atcggaagtc ttgaaatcaa caggtcaaaa
    40201 accagggaag gtttctgttg aaggaaaaga agtagaggtc acaggttcga ctgttaccag
    40261 ctattgggct aataagtcag gagcgccagc gacaagttat cgctttgcta ttggtggaag
    40321 tgatgcggat tatcagaatg cttggtctag tattgtgggg agtctaccaa ctccatccag
    40381 ctccagcagt tcaagtagta gttctagcga tagcagtaac tcaagtacta cacgaccttc
    40441 ttcaagggcg agacgataat tctctaaatg aagtggccaa tcaatggatt gccacttttt
    40501 tcctttcgtg ttacaataag ggtatgaatc agtatcagaa aaagattgtt aacggaaaaa
    40561 tttattcgct cctatccggc ttaatatggg gaatctgtgg aattttagga gagtacttct
    40621 ttactcatta tcaggtgtct tcgggctgga ttacctctat gcgtttgaca ctggcaggga
    40681 gtcttgtact catttggtct gcaatacaat taaaatcgca agtgctagat atttggcgag
    40741 acaagaaaaa ttacctgccc tttttagcct atgctatttt ggggattttt tcagttcagt
    40801 attttttcta tctctgtgta gaatactcaa atgctacgac agcaactatt ttacagttta
    40861 ttagccctgt ctttatcctc ttttataatc gcttggttta tcaaaaacga gcgtcaaaaa
    40921 gcgctgtttt ctatgttttg gttgccatgc tgggtgtttg cttgatggcg acaaagggag
    40981 atctctctca gttatccatg acgccgctag ctcttataac aggtttgctg agtgccatgg
    41041 gtgttatgtt taatgttatc ttgccccaac cttttgctaa gcgttatggt tttgttccta
    41101 cggttgggtg ggggatgatt ttggcaggtt tgtttagcaa tgtcctctcg ccggtttatc
    41161 agctttcctt tactcttgat atttggagta tcttgatttg cctcattatc gctttctttg
    41221 gaacggcttt tgcttttttc atttccatga aggctgtgtc cttggtttct cctttggtgg
    41281 ttgccgttat cagtgccagt gaacctctct cttctgctct cttgagtgtt ttgttcttag
    41341 gattagtagt ggattggtcc ctccttctag ctatagcctt gattatttta cccatgatat
    41401 ttttgtctat agaagaagcg aaagaaagta gataaaaagt cttttcttaa ttctaaaagt
    41461 gtgctatact agaatagtca ataaaacacg gggagatagt tgtgaagagt gtttttaggt
    41521 tgtatcggta ggggcttgct tttaccgaca gcacgtttta tctcacatcc ctaaaaaatc
    41581 atacctaaaa acagacaaaa aggtttcaaa tttgaggcct tttttggtag aataggtatc
    41641 attataacga accaggaggc acctatgact gctacaaaaa tgaacgctca agaaattatc
    41701 caatttatcg ccaatgctga aaagaaaacc agtgtcaaag taacctttga ggggcaactc
    41761 gcaactgctg tgcctagctc tgttgtcaaa ctaggaaatg tcctattcgg agactggaag
    41821 gacgtggctc cgcttcttga aggtttggta gaaaatcaag attatgttgt cgagcaagat
    41881 gctcgtaatt ctgcagttcc tttgctagat aagcgtgcta tcaacgctcg tatcgagcca
    41941 ggtgctatta tccgtgacca ggtggaaatt ggtgacaatg ctgttatcat gatgggagct
    42001 gttatcaata tcggtgctga aatcggtgct ggaaccatga ttgacatggg tgccatcctt
    42061 ggtggccgtg ctatcgttgg aaaaaatagc cacgttggtg caggtgcagt tttggcaggt
    42121 gtgattgagc cagctagtgc tgaaccagtc cgtgtcggag acaatgttct tatcggtgct
    42181 aatgcagtgg ttatcgaagg agtccaaatc ggtagtggtt cagttgtcgc tgcaggagct
    42241 atcgttaccc aagatgtccc agaaaacgtg gtagtagcag gtgttccagc tcgtatcatc
    42301 aaagaaattg atgcccaaac ccaacaaaaa acagcgctag aggatgcgct tcgtaccttg
    42361 taattgtaaa agtaaaaaag aggcggaacc ctttttccag cctctttctg ctatatcgga
    42421 ggacagatag atgttagatt tgattcagac tagacgagct ttacaccaga ttccagagat
    42481 tggcttggag gagttcaaga ctcaggctta tttgctggat gtgattgaga aattgactac
    42541 gggcaaggat tttgttcaaa ttcgtacttg gcggacaggg attttggtct acctgcaggg
    42601 aagtcagccg gagcgaacca ttggttggcg gacagatatt gatggcctgc ctatcgtcga
    42661 acaaacaggt ctaccttttg cttctcaaca ccaaggtcgc atgcatgcct gtggccatga
    42721 ttttcatatg accattgcct taggatgtct tgagcgcgcc cttgaggagc aacccaagaa
    42781 taatctgctc tttctatttc agcctgctga agaaaatgaa gctggtggta tgctcatgta
    42841 tgaggatggt gcttttggag attggttgcc aaaccaattc tatggtctcc atgttcgtcc
    42901 agatttgaaa gtcggccaga ttgcgactaa tactcataca ctctttgcag gaacttgcga
    42961 ggtgaagatc cgtttcaaag gcaaaggtgg ccacgcagct tttcctcatg aagccaatga
    43021 cgccttggtg gcggctagtt actttgtgac ccaagtgcag tcagttgtta gccgcaatgt
    43081 caacccaatc gagggagcag tggtgacctt cggcgttttt caagctggaa ccaccaacaa
    43141 tgtcatcaca gacacagctt ttttacatgg aactattcgt gccttgacac aggacatgag
    43201 tctcttggtg caaaagaggg taaaaacagt tgcagaaggg gttgcagctg cctttgatat
    43261 ggaagtcgaa gtggaactca aacaaggtgg atacctacct gttgagaaca atccagcctt
    43321 ggcgcgtgaa ctgatggact tctttgacga gaaagacgga atcgagttga ttgatatcga
    43381 acctgctatg acaggcgagg actttggtta tctcctttca aaggttgatg gcgtgatgtt
    43441 ttggctaggt atcgatagtc cctacgctct tcatcaccct caaatgagtc ctaaggaaga
    43501 agtcttagct attggggtgg ctgcggtgtc tagtttcctg aaaaagaagg cagcagaata
    43561 gagggcttgt ctatgaaatc ggaattacgc aagcaagtct tgcatgaaat gaagacttta
    43621 tctcaagaac aaaaacaggc tatagaccaa gctttaaccg agcgaatttt acaacacccc
    43681 ttttatcaag aagccaaggt catcgcaacc tacctctctt tttctcatga gtttcaaacg
    43741 cgggaactga ttgagcaggc gctgaaggac ggcaagaagg ttttgacacc taagacctat
    43801 cccaaggggc gcatggattt tgtggtctat gatccgcaac agttggtaaa aactgccttt
    43861 gccttactgg agccacaggg agatttggaa gtagtggatg catctcagat tgatttgatt
    43921 catgttcctg gtctggcttt tacgacgaaa ggatatcgga taggatacgg tggaggctat
    43981 tatgaccgct atctggaaca tttttctggt cgtactttga gtacgatata tccttgtcaa
    44041 attcaggact ttatacctga aaaccatgat attcctgttc aggaggtatt aattgatgaa
    44101 ggaaatcttt gatagacgtt accctgtgac gagtttcttc ctcttagtga cggccttggt
    44161 atttttacta atgttggtca ctgcaggcgg aaactttgac agggcagata cattatttcg
    44221 atttggagcc atgtatgggc cagctattcg cctctttccc gagcaggttt ggcgtctctt
    44281 gtctgccatt tttgttcata ttgggtggga acatttcatt gttaatatgc tttcacttta
    44341 ttatcttgga aggcaggtag aggagatttt cggttctaag cagtttttct ttctctatct
    44401 tttatcagga atgatgggca atctctttgt ttttgtattt agtcctaaat ccttagcagc
    44461 aggcgcctct acctctcttt atgggctatt tgccgcgatt attgttcttc gctatgcaac
    44521 tcgcaatcct tatattcaac agctagggca atcctatctg acactttttg tggttaacat
    44581 tattggaagt gttctgattc caggaatcag cctagcaggc catatcggtg gtgcagttgg
    44641 tggcgcattt ctagcagtta tctttccagt tagaggagaa aaacggatgt ataataccag
    44701 ccagagatta ggagcggtag tcttgttcgt aggactcgcc attttgcttt tctacaaggg
    44761 aatgggaatg tgacgaagtt gaaagaaaat ttgtgtaatg aaaaaagata aggcattttt
    44821 tgaaccttat ctttttattt tattccttct cagtcaattc ttttccaagt tggatgaggt
    44881 aattcttcaa atcatctttg acttgtgggt gtttgagggc gtagtcgatg gatgttttca
    44941 tgaagccaaa cttgtctccg acatcgtaac gagccccatt gaactcacga gcaaatacac
    45001 gttgtgtttt attgagggtg tcgattgcat ctgtcagctg aatttcattt cctgcacctg
    45061 gagcttggtt ttcgaggatt tggaaaattt caggcgtgag gaggtagcgt ccgataatag
    45121 caaggtcgct aggagcgtcc tctggagctg gtttttcaac aaaggtttca acactgtaaa
    45181 gaccatcttt tccttcgcct tgcggagcaa taaccccgta agcagatact tcgtcatgag
    45241 ggactggcat gacagcgata gtagacgcgt gggtacgctc gtagtcatcc atgagttgtt
    45301 tggtaagtgg aacagccttt tcgtctgtga tatccatcaa gtcatcacca agcataacga
    45361 caaaaggttc atttccgacg aaagccttgg cttgcaaaac agcatctccg agaccgcgtg
    45421 gatgagtttg gcggataaaa tgcagccgca tgtcagttgt tttatcaact agcttcaaaa
    45481 gatctgtttt ccctttttct ttgaggttat attccaattc gaagtttgaa tcaaagtggt
    45541 cctcaataga acgttttgat ttaccagtga caactagaat atcttcaata cctgatttga
    45601 gagcttcttc cacgataaac tggatagttg gtttgtctac gattggcaac atttctttgg
    45661 caagggcctt ggttgctggt aaaaatcgag ttcctagtcc agcagcaggg atgactgcct
    45721 ttctaacttt tgatgtcata aaaatccttt ctatagaggg ttaagaccac tcattttctg
    45781 ctttaaattc attgttcatg atgtcataaa tggcatcttt gatattggtt ccgtgataaa
    45841 taacttggta aatagcctgt gtaatgggca tatagactcc aagttcttgg gctagttcat
    45901 aggctgctcg agtcgttgaa attccttcga ttaccatgcc catattagct tctatatcag
    45961 ctagggattc tcctcgtccg agagcatctc cagctctcca gttacgagag tggatggaag
    46021 ttcccgttac gatcaaatct cccacaccag ataagccgct ataggtcaat ggactggccc
    46081 cgagtgctac ccctaggcgg gtgatttctg ctaaacctcg agcgatgatg gctgccttag
    46141 cattatcacc aaatccaaga ccatgtaaag ctccagcacc gacagcaata atatttttaa
    46201 gagcaccagc agtttcaacc ccgataacat ccgtattggt ataaagtcgg aagtagtgat
    46261 tactaaatag cttctgaacg tattgagctg tttgtaaatc tttagaagca gcagttatta
    46321 aagttaggtc acgcacaatg gtctcttctg catgactagg ccctgaaaca acgacgatat
    46381 cactacggag atgttcagga atttcttctt caagaatggt tgataatcgt ttatggctat
    46441 caggttctaa tccctttgat gcgtgcatga tgataacctt atggtccaag gtttgtgcaa
    46501 cttgctgggc aacaagtcgt gtcacttttg ttgggacaac aaacaaaatc gcatccacat
    46561 ctttcaatgt ttctgctaag tcggtgtagg caatgatatt ttcgtctaga acgacatctt
    46621 taaagtagtg cttattagta tggtgtgtat taatttcatt gatttgctcg ggaagatttc
    46681 cccaaatacg tacctcgtgt ccattgtcat ttaagacttg tgaaagggcg gttccccaag
    46741 aaccaggccc caagacggcg acggtttgtt tttccatgat ttcctccttg atagagttct
    46801 ttctcttatt ctatcatatt ctaggggatt ttgcacttgc attactgggg tatggtggaa
    46861 aaatacacaa aaaccgagac gaagggataa actcttagtc tttagttaaa gtgagaagaa
    46921 atctgataga tagtttgatt cagtatatgc ttataataga ggtaaacaac tcaggaggtt
    46981 cttgtaggtt gcgagagttt ggcgaaaaaa ttaaaagatt acgtttggct aaaaaaatca
    47041 gtcgttcaga attttgtggt gatgagtctg aattaagtat ccgtcaatta attagaattg
    47101 aaaatggaga atccagacca atactaacaa agttgaaata tattgctgaa cgtttggagg
    47161 ttgaagatta caagttgatg ccaagttata tagagttgga taaggaatac ctagaattga
    47221 agtatttctt gatgaggact cctacatacg aagatgaaac tatcgcccaa aagaaagaga
    47281 gtgttttgat aagatttttg aagagtatta tgataggcta cctgaggaag aaagatttat
    47341 catcccaaat tattcatatc tggcactaac gaactacaca gttcaaaaat taccagaaaa
    47401 gctagttgaa atactgtcct tctggtgatt ttgcttaatt tctgatgttc gagacataat
    47461 tgaggagatt tgtcttgatt ttttcctaaa aaagggcaga ctcctccctt ggtttgatgc
    47521 tcgattttta aaataaggtg acttattctg ttaggcatgt tttcccctgc cctctagctc
    47581 tatatggaac agggagtatc agatttatct ggcagattgt atcaaataag gcttgaaact
    47641 gttttgaata ggcatataga cttgagaatt tgagaatatg tcgtctagca gtagagacat
    47701 attttccggc aatatgaagg aagagacgtc gaaaacgctt gatagtcaag gcctttactt
    47761 catcaccagc tagctgcttt aaaaagaggt agagattata agccagacag cccatcatca
    47821 tacgtacttc attcttaatc atggtcgaac tatctgtctt atccccaaag aatcctgctt
    47881 tcctttcttt gataaagttt tcagcattcc ctcgttcacg atagaattga aacagctcct
    47941 cactatctac actgcttaaa ttggtcaaat gaactttttt acaaccataa aaaagagcac
    48001 ttaatcgtac tcttctcttt taaggattag ttgaattaat tcaaatccac tagttctcct
    48061 gtttctaggt agactaggcg ttcacaaatg ttagcaatgt aatcagcgaa gcgttccaga
    48121 tgccctatga tataaaggta ttgtgttcca ttgggaattg aggtttcttg gtctttcata
    48181 agtccaatga tttcctttga taaggcataa taatattggt caatctgttc atctttttga
    48241 gcaatactaa tagcttttga ggcttggtgc aaaggaaagg caaccaataa atcggatagc
    48301 atgctgaggg ataatttacc catttggtgt aactgttctt cgtcaggggc tagttgattt
    48361 tcttttagtt gcaaaacagc tttagcaatg cctgccatat ggtctcccat acgttcaagg
    48421 tctgaacaag aagacatgat gctaatcaca aatcgaaggt cagacacttg tggctgctgc
    48481 aaggccaaca aacgggcaca ggtcaattcg atagcgcttt gaccttggtt gatagcatga
    48541 tccttattga taattagctc tgccatctcc ttgtctttgg aggctaaggc cagtaaggtt
    48601 tttgaagctg tttcaaggac aagttgccct agtcctaaaa aggattgttc taattcatgc
    48661 aattctaagt caaattgatt tctcataggt ttttccttcc ttatccgaac cgtcctgaaa
    48721 tatagtcttc tgtgcgctga tcttttggat tggtaaacac gtcaacggtg tctccaaatt
    48781 cgcaaatttc tcctgttaag aaaaaagcag ttttatctga aatacgtgaa gcttgttgca
    48841 tgttatgggt aacaatgata atcgtataat ccttttttag ttgctgaatg aggtcttcaa
    48901 tttttaaagt ggagataggg tctaaggctg aagtcggctc atccattaac agaacatcag
    48961 gttctactgc taaagctcgc gcaatgcaaa ggcgttgctg ctgaccgcct gataaggaca
    49021 tggcactctt tttaagatta tctttgactt cgtcccaaat ggctgcccct tttaaagatt
    49081 tttccactaa ggcatctaat tgttttttgt ctcgaatacc atgtgtcctt gggccataag
    49141 ccacgttatc atagatagac atggcaaagg gattaggctg ttgaaaaacc atccctacac
    49201 gcttgcgtag ctgattaagg ttgaatttgc tactataaat atcttgctca tctaagagga
    49261 cttggccttc aatatggcaa gaaggaacca aatcgttcat ccgattaagg gtttttagaa
    49321 aagttgattt accacaacca gatgggccta tcaaggcagt aatctgtctt tctggtaatt
    49381 gaatcgaaat attttttaag gcttgaaaat ccccgtaaaa taagtctagg tgtctgactg
    49441 aaaatgttcc catactagga agctcctttc acaagttttc gagataataa gcttgataga
    49501 gtatttatca ttaaaacagt aataatcaaa atcacaccgg tagcataggc ttcattgaca
    49561 tgtagcccct cacttgacag catatacata tgcagggcta gagaacgacc tgaagacatg
    49621 agactacttg gcgtattggt agaggtacct aatgtataca tgagggcagc tgtctcacca
    49681 acgatacggc caatagctag tatcactcca gctaaaatac ctggcatggc aactggtaga
    49741 acaattctaa aaacagtccg taacttacct gccccaagtc cataacttgc ttgacgcatg
    49801 ctatcactaa cagataaaag ggcttcttct gttgagcgaa taatgactgg caacaccatg
    49861 atgactgagg ttaagattcc tgataacaga gagtattgaa aacctaagaa gactacaaag
    49921 aagagcatgc caaacagacc aaaaacaatg gaaggaatcc cagacaaggt atctgaggcc
    49981 aatcgcataa ttttaacaca aagggaatct ttttttgtat attccacaag ataaaaacca
    50041 gcaaaaatcc ctatgggcaa ggctaaaaga agagcaccaa aaaccagaat aacggtggaa
    50101 ataatcgctg gcataaggga aatgttctca gaagtataag tccaagaaaa gagggataga
    50161 cttagatgag gtaagccttt gatgaggata aaaccaatga ttaaaaagag agagccaaag
    50221 gttaaagctg aaaaacaata aacgagaagt tttagcaggt atttactcat aagatgattt
    50281 tcctttcaag taggcaaagt aggcattaat caagagaata aggaaaaaga gaactgctga
    50341 ggttgcaata agggcttccc tatgctgacc tgatgcgtaa gccatttcca gaacaatatt
    50401 ggttgttaag gttctggttc ctgaaaagag tccacttgga ataatcggct ggttgcctgc
    50461 caccaaaata actgccatgg tttcacctac tgcgcgaccg attcctaaaa taactgctga
    50521 taaaatacca gatctcgcag ctggcaagat gacactaaaa atactccgtt catgactagc
    50581 tcctagagcc aagctaccag aataatacgt tttgggaact gttcggatag cagattctga
    50641 caaactgata atggttggca aaatcattat tcctaatagt aacgaagcgg ttaggacact
    50701 catgccattt cctaaaaagg ttctaatcca aggcaccaat aattgtaggc cgaaaaaacc
    50761 ataaacaata gatggaatgg ccgccatcaa gttgatagct gattttaaga agccatagac
    50821 gggctttgga caataataaa ccataaacac cgatgtcaag atgcctgttg gcaccccaat
    50881 cacaatcgct cctaaggtaa ttaataagga accaacgatc attggtaaaa taccatagct
    50941 tgccggaatg ttcgttggcg accaatcact gcctaataaa aaacgggcaa agccgtagtt
    51001 agccatgaaa ggtaagccat tactaaaaat aaagaaacag attagcaaaa tagctacaac
    51061 agctactgtt gcactcatga aaaaaattgc cctaaaaact gcttctttga aggcttgttt
    51121 tatcacatct tgtcctttct agtgaagaaa gtaagggaga tacgacacct ccctacttgc
    51181 cttctttatc ttattgtacg atgaaacgtc tgcatctctt tagagattta tggagcaaac
    51241 attttattta atcttgtccc aggtggttaa tttgccacta aaaacgtctg caagttcagc
    51301 catactgact tggcttgcct tattgtcatt attgaccaca acagcaatac cgtctaaagc
    51361 aatagcatca tgggtgagac tcttaccttc ttcaggagtt aattccctag aaaccatacc
    51421 aatatcagcg gttttctcct taacagcggt aatacctgct gaagatccat tagaggtaat
    51481 atcaatcgta acttctggat tttctttttt ataagcttct gctaattttt ccattaaaga
    51541 agatactgaa gtggaaccta caacagacaa cttgcctgat aagtgttggc ttgtatattc
    51601 tgtggtttcg gttttagctt caataaattt attatctgtg accacttgtt gaccttgttt
    51661 ggagtggata aagctgataa aatcttgacc tagcttggaa agattagaag accaaacaat
    51721 gttgaaggga cgttgaagag ggtattcacc atctaaaact gtgtctcgac tagccttgac
    51781 accatcaatc tctaaagcct tgacagattt cgttaaagat cccaaggaga tgtagccgat
    51841 agcattagca ttcccttgaa ctgctgagag aacaccttct gtactatttt gaatcacagc
    51901 tgttttggta gtgttgtcaa tttttttatc accgtctttt ttgagaatcc ctgtgatttc
    51961 tgtgaaggca ccccgtgttc cagagccatt ttctcgtgaa atcacctcaa tcgttcctga
    52021 agctgactgt ttggaagcag ctgactgatt gccacaggca acaagcccaa atcctgataa
    52081 gccaatggct gcaagagtaa gcattttttt gaatttcata ataatcacct ttatctctat
    52141 gtatttttct tgtgtaggct tactacattt atagtctaac aagtctttgt aaaggtttat
    52201 ccctgattca tgtaaagatt gtgtaaagaa tcaaaaaaag ccacttttga aaaatggctg
    52261 ctcctaaaaa tagctttaaa aattattagt cctgtgcgaa agattggtta ggaagaaaaa
    52321 tcgtgaagca actgcctctg ccaagctgac tcgtcaccgt gacttggcca cctaataatt
    52381 gactgagttc tttgacaatg gcaaggccaa gaccagtgcc accagtttgt ctgcttcgac
    52441 ctttattaac tcggtaaaaa cgttcaaaaa tacgatcctg ctctaattga ctaataccaa
    52501 tccctgtatc tgatacagaa atcttaatgc cttcgttcac cttttgggtc ttgacctcaa
    52561 tttttccccc ttgttcagtg taacggatgg cattggataa aagattgagt aagatttggg
    52621 aaagtaattg actatctgat acgagggtga catcatctgg cacctgcacc tttagctgta
    52681 aatccttctt cttgagctga ggttgcaagc tttgagtcaa atcctgtaca aattctgcca
    52741 aagaaagggt cgtccattgt ataggcattt gttgagcctt agataaggta agaagatgct
    52801 caacaatatg ctcaagacgc aaactttctt tgtaaataat gtctagaaag tcatccttga
    52861 gcgcttcttc ttcagctgac atccccttaa tggtttcagc aaagccctta atcgaagtaa
    52921 ctggtgtcct caattcatgg gaggcatttg agacaaaggc taaatttaac ttttcataag
    52981 ttctaatcgt tgttaaatca tatagcaaga cgagcacagc ttccacagat tgggtggggc
    53041 taaaaacggg aactgctgtc acttctaaaa tcaagtcacc ctcatgaaac ccacttactt
    53101 cttgttttaa ccttgttttt tgatcaaagg cttggtgaac taaattccga atatccatcc
    53161 gtttgaggtc atcaagtgaa cttatgtcgc cgtccacatc gggaaaataa tgaggcagag
    53221 agcgactgga taataacatc tgaccttgag cggaaactaa aaacgtcccc atggttaggt
    53281 gcgacagaag aacctccatt gtttcggcta gatccttgta ttgctgatcc tgttgggaga
    53341 ctttggtttt taggccagac acatactgag ccaaagactt taagtcttct tgcccttttt
    53401 ctaaaaagta ttcactactg gtcaagagag gttggtgcaa ggtctcaaaa gcaacttccc
    53461 atttccaaag gcaaaagagc cagtagccac ctagtcccaa agaaagggct agaagaaaga
    53521 gaccgatgcc tttactgatc caagttaatg ccatccctgc aatcagaatg aggctaacac
    53581 ttagattgac tagccaaaat tgaaggtagc gtttcatcta taactccttg aacttataac
    53641 catacccccg aatggttcga ataaattgag gggctttagg attgtcttca attttttccc
    53701 ttaacttacc aatatgaacg tccaccaaac gtgtttcctg cccaaagtca tacccccaga
    53761 tacgttccaa aagacgctct ctagtcagtg tcatgttggg atgtttcata agatagagca
    53821 agagttcaaa ttcttttggg gtcaaactca gtaacttatt cgccttgtag acttcatgac
    53881 gctcagggta tactttcaag gtcccaaata gccaagaatc gtcagcgata ttatctgaat
    53941 catctccttc ttgttctcct ttagttcgcc tgaggacagc cttgacacgc gccagcaatt
    54001 ctctagggct aaaaggcttg gtcaggtagt catcagcccc taattccaag gccaaaacct
    54061 tatcaaattc atcacttttc gcagaaacca tcataattgg agttttgacg cctttggctc
    54121 tcagccgctt acaaacttcc atgccatcta attgtggtaa catgatatca agcaagataa
    54181 aatcaaaggg ttctgtttct gccaaagcta aggccttccg tccatttgtt accaattgag
    54241 tagaaaagcc ttccttactt aaatggtagt caagcaattt cagaatgtgt tcttcatcat
    54301 ccactaataa gacttgtttt gtcatctatt atctcctatt ggtaacatta taacacaatt
    54361 atcagaaatc ctaacattgc taaatcagat taaatttgct tatcaagact agtatctggt
    54421 caaacgctca atcatctcct tgtgctctgg ataggtcgcc agtagatcta ccctttcaaa
    54481 taattcaaaa tcctcaaatt caaaaccagg agcaacaaga caagaaacca gagcatcatc
    54541 cttatcaact gttgatcccc aaatagtgcc cttaggaaca cagtagtgaa gttgttgccc
    54601 tttggatatg tccaggccta aagtgactgc ttcgtagtga ccatctgctg taatcatgtg
    54661 aacagtaagt ggggattctg catgaaaata ccagatttca tctgctgtca atcggtgaaa
    54721 atgtgaagga ttcgtttctt cttaataaga aataaatact ggtataaagc gcccttccct
    54781 taccagcaag gtttatagtg tctgaagctt tttttgtttg tctaaaatag ccaccttcaa
    54841 catggggagc taactctaga gttcttatca agtcttcttt atccgtcgga gccaatgggt
    54901 tgaagtaact cttgttcaaa gtggtgttac gatttcaaga actcctctca gttctgagga
    54961 cacggtaatg attgatgcga cggaagtaca aatcaatcgc cctaaaagaa gaattagcga
    55021 atgattctgg taaaaaaaat gccacgctat gaaggctcaa gcgattgtca caagtcaagg
    55081 gagaattgtt tctttggata tcgctgtgaa ctattgtcat gatatgaagt tgttcaaaat
    55141 gagtcgcaga aatatcggac aagctggtaa aatcttggct gacagtggtt atcaagggct
    55201 catgaagata tatcctcaag cacaaactcc acgtaaatcc agcaaactca agccactaac
    55261 agttgaagat aaagcctata accatgcgct atccaaggag agaagcaagg ttgagaacat
    55321 ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg
    55381 cttcggatta cgaatgaatt tgattgctgg tattatcaat catgaactag gattctagtt
    55441 ttgcaggaag tctattattt ggttaggtga attagtgaag tgtttaggca agtgtctctg
    55501 gttacgacgt catggcctct aaatcgatta tatttagggg tcatgactag tgaagcagtt
    55561 agctagttcg catataagcg gctagcgtct aacaattagg aactttagtt ccaataactt
    55621 taagattacg acgttttagg acataaatcg atcatattta tgtcctaaaa ctagtgaagc
    55681 gcctagccaa agtccgaata ggatttggcg ttagttactt agattgcttt gcaatcaagt
    55741 aactttggcg atttacatct tctctggcgc ttctactcca agcaagcgaa gggcttcttt
    55801 gagaacgact gcggttgcgt agctgagggc tagacggctg tcgcgttctg ggctttcatc
    55861 caagatacgt gtatgtgcat agtatttgtt aaaggattga gccaggctaa ttgcaaattt
    55921 agcaatgata gaaggttcaa agttatctgc cgcacggttg ataatacgtg ggaagtcttg
    55981 aatgagttta atgatttccc agctttcagt atcattcaag ctatagttgc cagctgtttc
    56041 tggtttgaaa tcggctttgc gtaagataga ttggatacga gcgtaggcat attgaacgta
    56101 aggtccagtt tcaccctcga aggataccat agcttctagg tcgaagtcgt atccatttgt
    56161 acggtcggtt ttgaggtcat agaatttaat ggctccaacc ccaacagcat gtgctacttg
    56221 gtctttgttt tctagttcag gatttttagc ctcgatttgg accttggcac ggctaacagc
    56281 ctctgcaaca gtaggctcta gcaagatgac attcccttta cgagtagaga gtttcttccc
    56341 ttcttttgta accaaaccaa aaggaacgtg agtaatgtcg tcactccagt cgtagcccat
    56401 ctcttgcaag acagctttga gctgtttaaa gtgggcagat tgttcttgac caacgacata
    56461 gatagattta gcaaattggt attcgttttt acggtaaagg gctgcagcca agtcacgtgt
    56521 gatatagaga gttgcaccat cagatttctt gatgagggct ggatgttcaa ttccgtattt
    56581 ctcaagattg acaacttggg caccttctga ttcaagaagt agtccttttt cagaaagaat
    56641 gtctacaact gcatccatct tatcattgta gaaggcttct ccgttatagc tgtcaaattc
    56701 aaccttcaat tcattgtaaa ggcggttaaa ttccactaaa ctttcatcgc ggaaccattg
    56761 ccaaagagcg agagcttcct catctccatt ttcaagttta cggaaccatt cgcgcgcttc
    56821 ttcatccaag ctagggtcat ttttagcttc agcgttgatg cggacataga gtttaaggag
    56881 ttcatcgatt ggatgagctt ttacagcttc ttcgtcgccc cattttttgt aggcaacaat
    56941 caacatccca aattgtttac cccagtctcc caaatggttg accttgaccg tttgataacc
    57001 gattttttgg aaaatatgtg acaagctatc tccgataaca gttgaacgca ggtggccaat
    57061 agaaaatggt ttagcgatat tcggactaga catgtcgata acaacatttt cttgtttgcc
    57121 aatattttgg tcagcatagt gttctttttc agtggtaaca gcttgcaata cttgagcaga
    57181 aatggcagat ttatcaagga aaaagttaac gtaaggtcct gttgcgacaa ctttttcaaa
    57241 ggcttggctg ttcatttttt cagccagttc agccgcaatc atttgtggtg ctttacgttc
    57301 gacttttgca agagaaaaag cagggaaagc aatgtctccc atttctgagt ttttaggggt
    57361 ttccagtaac tttaaaatag cctcttggtc caggctatca atgatgctag ataattcgct
    57421 agcaatcaat tcttttgtat tcattaagag ctcctttttg gacttttcta ctattttatc
    57481 acaattttaa agaaagaaga aaaaattttt gaaatctcct gtttttttgg tataatatgg
    57541 ttataaatat agttataaat atgcacgcaa gaggatttta tgagaaaaag agatcgtcat
    57601 cagttaataa aaaaaatgat tactgaggag aaattaagta cacaaaaaga aattcaagat
    57661 cggttggagg cgcacaatgt ttgtgtgacg cagacaacct tgtctcgtga tttgcgcgaa
    57721 atcggcttga ccaaggtcaa gaaaaatgat atggtgtatt atgtactagt aaatgagaca
    57781 gaaaagattg atttggtgga atttttgtct catcatttag aaggtgttgc aagagcagag
    57841 tttaccttgg tgcttcatac caaattggga gaagcctctg ttttggcaaa tattgtagat
    57901 gtaaacaagg atgaatggat tttaggaaca gttgctggtg ccaatacctt attggttatt
    57961 tgtcgagatc agcacgttgc caaactcatg gaagatcgtt tgctagattt gatgaaagat
    58021 aagtaaggtc ttgggagttg ctctcaagac ttatttttga aaaggagaga cagaaaatgg
    58081 cgatagaaaa gctatcaccc ggcatgcaac agtatgtgga tattaaaaag caatatccag
    58141 atgctttttt gctctttcgg atgggtgatt tttatgaatt attttatgag gatgcggtca
    58201 atgctgcgca gattctggaa atttccttaa cgagtcgcaa caagaatgcc gacaatccga
    58261 tccctatggc gggtgttccc tatcattctg cccaacagta tatcgatgtc ttgattgagc
    58321 agggttataa ggtggctatc gcagagcaga tggaaaatcc taaacaagca gttggggttg
    58381 ttaaacgaga ggttgttcag gtcattacgc cagggacagt ggtcgatagc agtaagccgg
    58441 acagtcagaa taattttttg gttgccatag accgcgaagg caatcaattt ggcctagctt
    58501 atatggattt ggtgacgggt gacttttatg tgacaggtct tttggatttc acgctggttt
    58561 gtggggaaat ccgtaacctc aaggctcgag aagtggtgtt gggttatgac ttgtctgagg
    58621 aagaagaaca aatcctcagc cgccagatga atctggtact ctcttatgaa aaagaaagct
    58681 ttgaagacct tcatttattg gatttgcgat tggcaacggt ggagcaaacg gcatctagta
    58741 agctgctcca gtatgttcat cggactcaga tgagggaatt gaaccacctc aaacctgtta
    58801 tccgatacga aattaaggat ttcttgcaga tggattatgc gaccaaggct agtctggatt
    58861 tggttgagaa tgctcgctca ggtaagaaac aaggcagtct tttctggctt ttggatgaaa
    58921 ccaaaacggc tatggggatg cgtctcttgc gttcttggat tcatcgcccc ttgattgata
    58981 aggaacgaat cgtccaacgt caagaagtag tgcaggtctt tctcgaccat ttctttgagc
    59041 gtagtgactt gacagacagt ctcaagggtg tttatgacat tgagcgcttg gctagtcgtg
    59101 tttcttttgg caaaaccaat ccaaaggatc tcttgcagtt ggcgactacc ttgtctagtg
    59161 tgccacggat tcgtgcgatt ttagaaggga tggagcaacc tactctagcc tatctcatcg
    59221 cacaactgga tgcaatccct gagttggaga gtttgattag cgcagcgatt gctcctgaag
    59281 ctcctcatgt gattacagat gggggaatta tccggactgg atttgatgag actttagaca
    59341 agtatcgttg cgttctcaga gaagggacta gctggattgc tgagattgag gctaaggagc
    59401 gagaaaactc tggtatcagc acgctcaaga ttgactacaa taaaaaggat ggctactatt
    59461 ttcatgtgac caattcgcaa ctaggaaatg tgccagccca ctttttccgc aaggcgacgc
    59521 tgaaaaactc agaacgcttt ggaaccgaag aattagcccg tatcgaggga gatatgcttg
    59581 aggcgcgtga gaagtcagcc aacctcgaat acgaaatatt tatgcgcatt cgtgaagagg
    59641 tcggcaagta catccagcgt ttacaagctc tagcccaagg aattgcgacg gttgatgtct
    59701 tacagagtct ggcggttgtg gctgaaaccc agcatttgat tcgacctgag tttggtgacg
    59761 attcacaaat tgatatccgg aaagggcgcc atgctgtcgt tgaaaaggtt atgggggctc
    59821 agacctatat tccaaatacg attcagatgg cagaagatac cagtattcaa ctgattacag
    59881 ggccaaacat gagtgggaag tctacctata tgcgtcagtt agccatgacg gcggttatgg
    59941 cccagctggg ttcctatgtt cctgctgaaa gcgcccattt accgattttt gatgcgattt
    60001 ttacccgtat cggagcagca gatgacttgg tttcgggtca gtcgaccttt atggtggaga
    60061 tgatggaggc caataatgcc atttcgcatg cgaccaagaa ctctctcatt ctctttgatg
    60121 aattgggacg tggaactgca acttatgacg ggatggctct tgctcagtcc atcatcgaat
    60181 atatccatga gcacatcgga gctaagaccc tctttgcgac ccactaccat gagttgacta
    60241 gtctggagtc tagtttacaa cacttggtca atgtccacgt ggcaactctg gagcaggatg
    60301 ggcaggttac cttccttcac aagattgaac cgggaccagc tgataaatcc tacggtatcc
    60361 atgttgccaa gattgctggc ttgccagcag accttttagc aagggcggat aagattttga
    60421 ctcagctaga gaatcaagga acagagagtc ctcctcccat gagacaaact agtgctgtca
    60481 ctgaacagat ttcactcttt gatagggcag aagagcatcc tatcctagca gaattagcta
    60541 aactggatgt gtataatatg acacctatgc aggttatgaa tgtcttagta gagttaaaac
    60601 agaaactata aaaccaagac tcactagtta atctagctgt atcaaggaga cttctttgac
    60661 aattctccac ttttttgcta gaataacatc acacaaacag aatgaaaagg agctgacgca
    60721 ttgtcgctcc cttttgtcta ttttttaagg agaaagtatg ctgattcaga aaataaaaac
    60781 ctacaagtgg caggccctgg cttcgctcct gatgacaggc ttgatggttg ctagttcact
    60841 tctgcaaccg cgttatctgc aggaagtctt aggcgccctc cttactggga aatatgaagc
    60901 tatttatagt atcggggctt ggttgattgg tgtggccgta gtcggtctag ttgctggtgg
    60961 actcaatgtt gtcctcgcag cctatattgc ccaaggagtt tcatccgacc ttcgggagga
    61021 tgccttccgt aaaattcaaa ccttttctta tgctgatatt gaacaattta atgcgggaaa
    61081 tctagtcgtt cgaatgacaa atgatatcaa ccagattcag aacgttgtca tgatgacctt
    61141 ccaaattctt ttcagacttc ccctcttgtt catcggttcg tttatcctag cggttcaaac
    61201 cttaccttct ctgtggtggg tgattgttct catggtagtc ttgatttttg gtttgactgc
    61261 tgtcatgatg ggaatgatgg ggcctcgttt tgccaagttt caaacccttc ttgagcgcat
    61321 caatgccatt gccaaggaaa atttacgtgg cgttcgtgtg gtcaagtcct ttgtccaaga
    61381 aaaagagcaa tttgctaagt ttacagaggt ctcagacgag cttcttggtc aaaaccttta
    61441 cattggttat gccttttcag tagtggaacc ctttatgatg ttggttggtt acggggcggt
    61501 cttcctctct atttggctgg tcgcgggaat ggttcagtcg gatccgtctg ttgttggttc
    61561 catcgcttct tttgttaatt acctaagcca gattatcttt accattgtta tggttggatt
    61621 tttgggaaat tctgtcagcc gtgccatgat ttccatgcgt cgtattcgag aaattcttga
    61681 cgcagagcca gctatgacct tcaaggatat cccagatgaa gagttggttg gaagccttag
    61741 ctttgaaaat gtgaccttta cctatccaat ggacaaggaa ccgatgctga aagatgtgag
    61801 ctttactatt gaacctggtc aaatggttgg tgtagttgga gcgactggtg caggaaagtc
    61861 aaccttggct caattgattc cacgtctctt tgatccacag gaaggggcta tcaaaatcgg
    61921 aggtaaggat attcgagaag tgagtgaagg gaccctgcgt aaaacagttt ccatcgttct
    61981 ccaacgtgcc attcttttta gtggaacgat tgcagataac ttgagacagg ggaagggaaa
    62041 tgctactcta tttgaaatgg agcgcgcagc caatattgcc caggctagtg aattcattca
    62101 tcgtatggag aaaacctttg aaagtccagt tgaagaacgg ggaaccaatt tctctggtgg
    62161 acaaaaacaa aggatgtcga ttgcgcgtgg gattgtcagc aatccacgta ttctgatttt
    62221 tgatgattcg acctcagcct tggatgccaa atcagagcgc ttggtgcaag aagctttgaa
    62281 taaggacttg aaggggacga caactattat tattgctcaa aaaattagct cggttgtcca
    62341 tgcagacaag atcttggttc taaatcaagg acgattgatt ggtcaaggca cgcatgcaga
    62401 cttggttgcc aacaatgccg tttaccgtga aatctatgaa acacagaaa
//
LOCUS       DAVLIK010000007        59569 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLIK010000007 DAVLIK010000000
VERSION     DAVLIK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.007"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..215
                     /locus_tag="VXE87_000447"
     CDS             <1..215
                     /locus_tag="VXE87_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV0842051.1"
                     /translation="WYYLNANGDMETGWVKDGDTWYYLEASGAMKASQWFKVSDKWYY
                     VNGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(445..1425)
                     /gene="dusB"
                     /locus_tag="VXE87_000448"
     CDS             complement(445..1425)
                     /gene="dusB"
                     /locus_tag="VXE87_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0842052.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1412..2284)
                     /gene="hslO"
                     /locus_tag="VXE87_000449"
     CDS             complement(1412..2284)
                     /gene="hslO"
                     /locus_tag="VXE87_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0842053.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2449..3876
                     /locus_tag="VXE87_000450"
     CDS             2449..3876
                     /locus_tag="VXE87_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0842054.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4035..5167
                     /gene="glpK"
                     /locus_tag="VXE87_000451"
                     /pseudo
     CDS             4035..5167
                     /gene="glpK"
                     /locus_tag="VXE87_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
     gene            5209..7035
                     /gene="glpO"
                     /locus_tag="VXE87_000452"
     CDS             5209..7035
                     /gene="glpO"
                     /locus_tag="VXE87_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0842055.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            7105..7809
                     /locus_tag="VXE87_000453"
     CDS             7105..7809
                     /locus_tag="VXE87_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0842056.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8106..8309
                     /locus_tag="VXE87_000454"
     CDS             8106..8309
                     /locus_tag="VXE87_000454"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842057.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(8396..8983)
                     /locus_tag="VXE87_000455"
     CDS             complement(8396..8983)
                     /locus_tag="VXE87_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842058.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10093..11370
                     /gene="ltrA"
                     /locus_tag="VXE87_000456"
                     /pseudo
     CDS             10093..11370
                     /gene="ltrA"
                     /locus_tag="VXE87_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            11822..12532
                     /locus_tag="VXE87_000457"
     CDS             11822..12532
                     /locus_tag="VXE87_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0842059.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLLYQQI
                     YWKFFQIRFGFLPLYLFL"
     gene            12478..12999
                     /locus_tag="VXE87_000458"
     CDS             12478..12999
                     /locus_tag="VXE87_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0842060.1"
                     /translation="MEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISG
                     LIAFRLSEKFLAAKWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVP
                     ESVFLQETVEENHLVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMI
                     EAILIYIRRDYFK"
     gene            13313..13444
                     /locus_tag="VXE87_000459"
     CDS             13313..13444
                     /locus_tag="VXE87_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0842061.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13465..15015
                     /gene="dltA"
                     /locus_tag="VXE87_000460"
     CDS             13465..15015
                     /gene="dltA"
                     /locus_tag="VXE87_000460"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0842062.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIAQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15012..16256
                     /gene="dltB"
                     /locus_tag="VXE87_000461"
     CDS             15012..16256
                     /gene="dltB"
                     /locus_tag="VXE87_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0842063.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16270..16509
                     /gene="dltC"
                     /locus_tag="VXE87_000462"
     CDS             16270..16509
                     /gene="dltC"
                     /locus_tag="VXE87_000462"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0842064.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16502..17770
                     /gene="dltD"
                     /locus_tag="VXE87_000463"
     CDS             16502..17770
                     /gene="dltD"
                     /locus_tag="VXE87_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0842065.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            17925..18365
                     /gene="adcR"
                     /locus_tag="VXE87_000464"
     CDS             17925..18365
                     /gene="adcR"
                     /locus_tag="VXE87_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0842066.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18365..19069
                     /locus_tag="VXE87_000465"
     CDS             18365..19069
                     /locus_tag="VXE87_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0842067.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19062..19868
                     /locus_tag="VXE87_000466"
     CDS             19062..19868
                     /locus_tag="VXE87_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0842068.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            19878..21383
                     /gene="adcA"
                     /locus_tag="VXE87_000467"
     CDS             19878..21383
                     /gene="adcA"
                     /locus_tag="VXE87_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0842069.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVPNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22503..23276)
                     /locus_tag="VXE87_000468"
     CDS             complement(22503..23276)
                     /locus_tag="VXE87_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0842070.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPNQKLLDAVELFDGEWVSDIQ"
     gene            23452..24855
                     /locus_tag="VXE87_000469"
     CDS             23452..24855
                     /locus_tag="VXE87_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0842071.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFSTEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            24970..25608
                     /locus_tag="VXE87_000470"
     CDS             24970..25608
                     /locus_tag="VXE87_000470"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV0842072.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            25620..26060
                     /locus_tag="VXE87_000471"
     CDS             25620..26060
                     /locus_tag="VXE87_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV0842073.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26053..26484
                     /locus_tag="VXE87_000472"
     CDS             26053..26484
                     /locus_tag="VXE87_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0842074.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26475..26945
                     /locus_tag="VXE87_000473"
     CDS             26475..26945
                     /locus_tag="VXE87_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0842075.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            26970..27743
                     /locus_tag="VXE87_000474"
     CDS             26970..27743
                     /locus_tag="VXE87_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0842076.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            27740..28540
                     /locus_tag="VXE87_000475"
     CDS             27740..28540
                     /locus_tag="VXE87_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0842077.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28599..30893
                     /locus_tag="VXE87_000476"
     CDS             28599..30893
                     /locus_tag="VXE87_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0842078.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELCIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            30903..34019
                     /locus_tag="VXE87_000477"
     CDS             30903..34019
                     /locus_tag="VXE87_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0842079.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34076..35842
                     /locus_tag="VXE87_000478"
     CDS             34076..35842
                     /locus_tag="VXE87_000478"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0842080.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            35988..37139
                     /locus_tag="VXE87_000479"
     CDS             35988..37139
                     /locus_tag="VXE87_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0842081.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37284..38168
                     /locus_tag="VXE87_000480"
     CDS             37284..38168
                     /locus_tag="VXE87_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0842082.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            38567..38818
                     /locus_tag="VXE87_000481"
     CDS             38567..38818
                     /locus_tag="VXE87_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0842083.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQATE
                     TSSALISSHYLDEQDLSEKLKSELQWLELENKLLNLWEH"
     gene            38806..39093
                     /locus_tag="VXE87_000482"
                     /pseudo
     CDS             38806..39093
                     /locus_tag="VXE87_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(39276..39403)
                     /locus_tag="VXE87_000483"
                     /pseudo
     CDS             complement(39276..39403)
                     /locus_tag="VXE87_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(39498..40829)
                     /locus_tag="VXE87_000484"
     CDS             complement(39498..40829)
                     /locus_tag="VXE87_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0842084.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPGKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(40851..42362)
                     /locus_tag="VXE87_000485"
     CDS             complement(40851..42362)
                     /locus_tag="VXE87_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0842085.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(42571..43518)
                     /gene="arcC"
                     /locus_tag="VXE87_000486"
     CDS             complement(42571..43518)
                     /gene="arcC"
                     /locus_tag="VXE87_000486"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0842086.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(43683..44699)
                     /gene="argF"
                     /locus_tag="VXE87_000487"
     CDS             complement(43683..44699)
                     /gene="argF"
                     /locus_tag="VXE87_000487"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0842087.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(44757..45986)
                     /gene="arcA"
                     /locus_tag="VXE87_000488"
     CDS             complement(44757..45986)
                     /gene="arcA"
                     /locus_tag="VXE87_000488"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0842088.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDESKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            46741..48420
                     /locus_tag="VXE87_000489"
     CDS             46741..48420
                     /locus_tag="VXE87_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0842089.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(48460..50619)
                     /locus_tag="VXE87_000490"
     CDS             complement(48460..50619)
                     /locus_tag="VXE87_000490"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0842090.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPLDI
                     IETGEADRTFFDHCLYRLFLFPQTFYEVDESGKAIHMDLATGTVNPGVLFSNNGFWDT
                     FRTTFPLFALIIPEHYQRFLEGFLNSYRDTGFLPKWLAPDERGMMPGTLLDGIIADSA
                     CKDMAPDLEGELFQAMLETASKADPLGINGRHGLAQYQELGYLSTDHHESVSHTLDYA
                     YSDFCIASCAKKLENIEIAETYKAASQNYRQLFDAETGYMRARDNQGNFHPDFSPYSW
                     GRDYAECSAIQATLGVLHDIPGLIQLMGGKETFSNYLLKACQDAPLFETTGYGYEIHE
                     MSEMATAPFGQIAISNQPSFHIPYLFRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDE
                     DNGSLSAWYIWSALGFYPTCPGKPSYDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHF
                     NFVKECRLNKTLVSTIQHQDLLKAEQLTFTLSWLPSH"
     gene            50790..52070
                     /locus_tag="VXE87_000491"
     CDS             50790..52070
                     /locus_tag="VXE87_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0842091.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDSLLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            52161..54806
                     /locus_tag="VXE87_000492"
     CDS             52161..54806
                     /locus_tag="VXE87_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0842092.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFELFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVQLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTSFTSLQLARQEGS
                     VVAIGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            54889..55758
                     /locus_tag="VXE87_000493"
     CDS             54889..55758
                     /locus_tag="VXE87_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0842093.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSIPTPKNLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHCFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAGKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNCNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            55752..57632
                     /locus_tag="VXE87_000494"
     CDS             55752..57632
                     /locus_tag="VXE87_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0842094.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            58010..58372
                     /locus_tag="VXE87_000495"
     CDS             58010..58372
                     /locus_tag="VXE87_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842095.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(58442..58831)
                     /locus_tag="VXE87_000496"
     CDS             complement(58442..58831)
                     /locus_tag="VXE87_000496"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0842096.1"
                     /translation="MKAQAIVTSQGRIVSLDITVNYCHDMKLFKMSCRNIGQAGKILA
                     DSGYQGPMKIYPQAQTPRKSSKLKPLTAEDKACNHALSKERSKVENIFAKVETFKMFS
                     TTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(58848..59156)
                     /locus_tag="VXE87_000497"
     CDS             complement(58848..59156)
                     /locus_tag="VXE87_000497"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEV0842097.1"
                     /translation="MLKTAYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEEIATD
                     FGIHESNLIRRSQWVEVTLVQSGVTISRTPLSSEDTVMIDATEVKINRPKKTISESFW
                     "
     gene            complement(59247..59425)
                     /locus_tag="VXE87_000498"
                     /pseudo
     CDS             complement(59247..59425)
                     /locus_tag="VXE87_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
BASE COUNT        17940 a        10927 c        13073 g        17629 t
ORIGIN      
        1 catggtacta cctaaacgct aatggtgata tggagacagg ttgggtgaaa gatggagata
       61 cctggtacta tcttgaagca tcaggtgcta tgaaagcaag ccaatggttc aaagtatcag
      121 ataaatggta ctatgtcaat ggctcaggtg cccttgcagt caacacaact gtagatggct
      181 atggagtcaa tgccaatggt gaatgggtaa actaaaccta atataactag ttaatactga
      241 cttcctgtaa gaactcttta aagtattccc tacaaatacc atatcctttc agtagataat
      301 atacccttgt aggaagttta gattaaaaaa taactctgta atctctagcc ggatttatag
      361 cgctagagac tacggagttt ttttgatgag gaaagaatgg cggcattcaa gaggctcttt
      421 aagagagtta cgggttttaa actattaagc cttctccaat tgcaagaggg cttcaatctc
      481 tgccagggtg ctagcttgcg aaatggctcc acggagtttg gcagcgccag atgttccacg
      541 gaggtagtga ggagcgaggc cgcggaattc acgaactgcg acgttttctc ctttgaggtt
      601 aatcaatcgt ttcaagtgtt cgtaggcgat cttcatcttg tcttcaaagg tcaaatcagg
      661 taggatttct cctgtttcaa agtaatggtt gatttggttg aagaggtaag gatttcccat
      721 ggcagctcgg ccaatcatga ctgcgtcagc accaacttct tcgatgcgtt gcttggcttc
      781 ttggacagta cggatatcac cgttggcgat gaatggaatc ttggttagag cttgggcaac
      841 cttgtaaagg gtctcaaggt ctgcgtggcc agtatacatt tgttcacggg tacggccatg
      901 catggcgagg gcagaaacac ctgcagcctc agcagcgagg gcattctcta ctgccagaga
      961 tgggtccgcc cagccggtac gcattttgac agtaagtggg atatcaagga cagactggac
     1021 cttgttgatg atagagtaga tcttgtcagg atccttgagc cacatagcac cagcttcgtt
     1081 cttcacgatt ttgttgacag ggcagcccat gttgatatcg acgatatcgg tcttagtgtt
     1141 ttcttggata aattctgctg cgcgtgctag gctgtcttca tcgctaccaa aaagttggat
     1201 agagacaggg ttttcgccct catcgatatg aagcatgtgc agggtttttt cgttgttgta
     1261 ttggattccc ttgtcagaga ccatttccat tacaacgagt ccagctccga gctcttttgc
     1321 aatggtacga aaggctgagt tggtcacgcc agccataggc gctaaaacgg tacgattggg
     1381 aatctcaaca ttgccaatca taaaaggtgt attaagattt gtcacgaatg agttcctcca
     1441 ggtccttttc atcaaagttg taagtagttt ggcagaattg acaagtgatt tctgccccgt
     1501 ggtcttcctc tttcatttcc tgtaagtctg agcttggaag gctggcaaga gcgttcataa
     1561 agcgttcatg gctacagtca cattggaaac ggatttcttc ttcagaaaga cgcttgtagg
     1621 cctcgtcacc gtagatagcc ttgaggaggg cttcgatatg gtcgtcgctt tcgagaagag
     1681 tagagatagc tggcatttct tggatgcgtt tttcaaagcg agcaatctct tctttcttgg
     1741 ctcctggcaa gacttgaact aggaaaccac ctgcaacctt gaccttgtct tcctcgtcca
     1801 aaaggacatt gaggccgacc gctgaaggcg tttgttggct ttcagtaagg taaaaggcaa
     1861 ggtcttcacc gatttctcca gagatgaggg gagttataga gttgtaagga tttccagtac
     1921 cgtagtctgt gataacaagg aattgaccat ttccaacaaa aggtccgact aggacttcac
     1981 cagtcgcagt ctttttgatg tcaacaccag gattttgaac atagcctttg acgttcccct
     2041 tggtatcagc gacggtgata atagcaccta gagagctaga gcccaacacc ttaactgtaa
     2101 gtttggtatt tcctttttca ttggctgcga gaatctggct ggcgataaga gttcgaccaa
     2161 gcgctacagt tgagctagct tgggtttgat gtttttcttg agcagtgcgg acggtttcag
     2221 tgctatcaag gacaaaagca cgaaaggctc cgctttctga tatagtttta ataattttat
     2281 ccatagctac tattttagca taaaaatgcc caaaggggga gccgtgtgtt tactgatttt
     2341 caggataatg gaccaggaaa tcagcatgaa aataaaaaga gaaacagatt attttagcat
     2401 ttgtaagatt tatgctatgc ttaaggtaga aaatgaaagg ggtaacaaat gtatttagga
     2461 gatttgatgg agaaagccga gtgtggtcaa ttttcaatcc tttcctttct attacaagag
     2521 tctcagacga ccgtcaaggc tgtaatggaa gaaacaggat tttcaaaagc aaccctaacc
     2581 aaatatgtca ccctgctcaa tgacaaggct ttggatagtg gcttagagct gactattcac
     2641 tcagaagatg aaaatctgcg tctgtctatc ggtgcagcta ccaaggggag agatattcgg
     2701 agcttgtttt tggagagtgc tgttaaatac cagattttgg tttatcttct ctaccaccaa
     2761 cagtttttag cccatcagct ggctcaagaa ttagtgatta gcgaggctac gcttggtcgt
     2821 cacttggctg gtttaaatca gattttgtca gaatttgatt tatccatcca aaatggacgt
     2881 tggcgaggtc cagagcatca gattcgctat ttctatttct gtcttttccg aaaggtctgg
     2941 tcgagtcagg aatgggaagg tcacatgcag aaaccagaga gaaaacagga gattgccaat
     3001 ttagaggaaa tctgcggtgc aagtttgtct gcgggacaga aattggactt ggttctctgg
     3061 gctcacatca gtcaacaacg tcttcgggtc aatgcttgtc agtttcaagt catagaagag
     3121 aaaatgcgag ggtattttga caatatcttc tatcttcgtt tgctgagaaa ggttccgtcc
     3181 ttttttgctg ggcaacatat tccactagga gttgaggatg gtgagatgat gatattcttc
     3241 tcttttctcc tatctcatcg cattcttcct cttcatacta tggaatatat tcttggtttt
     3301 ggagggcagt tggcagattt actgacgcaa ttgattcaag aaatgaagaa ggaggaacta
     3361 ttgggggatt atacagagga ccatgtcacc tatgaactca gtcagctttg tgctcaagtc
     3421 tatctctata agggctatat tttacaggat cgctacaagt accagttaga gaatcgtcat
     3481 ccatatttac tgatggaaca tgattttaaa gagacagcag aggagatttt tcatgctcta
     3541 cctgcttttc aacaggggac agatttagat aagaagattc tctgggaatg gctccagtta
     3601 atcgaatata tggctgaaaa cggtggccag catatgcgga ttggtctgga tttgacatct
     3661 ggttttcttg tcttttcaag gatggcagcc attttgaaac ggtatttgga atacaatcgt
     3721 tttattacca ttgaagctta tgaccctagt cggcattatg atttgctggt taccaataac
     3781 ccgattcata agaaggaaca gacaccagtc tattatttaa aaaatgactt ggatatggag
     3841 gatttggcag ggattcgtca gttattattc acttaaaagg cttggttaat ccaggtcttt
     3901 tttgtgaaat tcacacaatc tcctcacatt tttttaaaaa ttaaaaaaag ttgataaaca
     3961 agaaagcgct ttattttgta tactagtaag tgtaaagagg aaacacctca agatctttat
     4021 caggaggaca gtatatgtca caagaaaaat acatcatggc cattgaccag ggaactacaa
     4081 gttctcgtgc catcattttc aacaaaaaag gggaaaaggt tagctcgagt caaaaagagt
     4141 ttacccagat tttccctcag gcaggttggg ttggaaattg actgacggtg cggctcacgt
     4201 gactgactac tcaaatgcag ctcgtaccat gctttataac attaaagaac tcaaatggga
     4261 tgatgaaatt ttggaaatcc ttaacattcc gaaggctata cttccagaag ttcgttctaa
     4321 ctccgaaatc tacggcaaga cagctccatt ccatttctac ggtggagagg tgccaatctc
     4381 aggtatggct ggggaccaac aagcagccct ctttggacag ttggcttttg agccaggtat
     4441 ggttaagaat acttatggaa caggctcttt catcatcatg aatactgggg aagagatgca
     4501 gttgtctgaa aacaacctct tgacaaccat tggttacgga atcaacggta aggtttatta
     4561 tgccttggaa ggttctatct tcatcgcagg aagtgctatt cagtggcttc gtgacggtct
     4621 tcgcatggtt gaaaattcac cagaatctga aaaatacgct cgtgattctc acaacaacga
     4681 tgaagtttat gtcgttccag cctttacagg tctaggcgct ccatactgga accaaaatgc
     4741 tcgtggttcc gtctttggtt tgactcgtgg aacaagcaaa gaagacttta tcaaggcgac
     4801 tttgcaatct attgcttatc aagtgcgtga catcatcgac accatgcaag tggatactca
     4861 gaccgccatt caagtactga aggtggatgg tggtgcagcc atgaacaact tcctcatgca
     4921 attccaggcg gatattttag gcattgacat tgcacgtgct aaaaacttgg aaacaacagc
     4981 tctaggagcg gccttcctag caggtttgtc agtagggtac tggaaagact tggacgagtt
     5041 gaaactcttg aacgagacag gagaactctt tgagccatct atgaatgaat ctcgcaagga
     5101 acaactctac aagggctgga agaaggctgt gaaagcaact caagtctttg cggaagtaga
     5161 cgactaatac tggcagaata aagcgattta tttagaaagt gtgtaaatat ggaattttca
     5221 aagaaaacac gtgaattgtc aattaaaaaa atgcaggaac gcaccctgga cctcttgatt
     5281 atcggtggag gaatcacagg agctggtgta gccttgcagg cggcagctag cggtcttgag
     5341 actggtttga ttgaaatgca agactttgca gaaggaacat ctagtcgttc aacaaaattg
     5401 gttcacggag gacttcgtta cctcaaacaa ttcgacgtcg aagtggtctc agatacggtt
     5461 tctgaacgtg cagtggttca acaaatcgct ccacacattc caaaaccaga cccaatgctc
     5521 ttaccagttt acgatgaaga tggagcaacc tttagcctct tccgtcttaa agtagccatg
     5581 gacttgtacg acctcttggc aggtgttagc aacacaccaa ctgcgaacaa ggttttgagc
     5641 aaggatcaag tcttggaacg ccagccaaac ttgaagaagg aaggcttggt aggaggtgga
     5701 gtgtatcttg acttccgtaa caacgatgcg cgtctcgtga ttgaaaacat caaacgtgcc
     5761 aaccaagacg gtgccctcat tgccaaccac gtgaaggcag aaggcttcct ttttgacgaa
     5821 agtggcaaga ttacaggtgt tgtagctcgt gatctcttga cagaccaagt atttgaaatc
     5881 aaggcccgtc tggttattaa tacaacaggt ccttggagtg ataaagtacg taatttgtct
     5941 aataagggaa cgcaattctc acaaatgcgc ccaactaagg gagttcactt ggtagtggat
     6001 tcaagcaaaa tcaaggtttc acagccagtt tactttgaca caggtttggg tgacggtcgt
     6061 atggtctttg ttctcccacg tgaaaacaag acttactttg gtacaactga tacagactac
     6121 acaggtgatt tggagcatcc aaaagtaact caagaagatg tagattatct acttggcatt
     6181 gtcaacaacc gctttccaga atccaacatc accattgatg atatcgaaag cagctgggca
     6241 ggtcttcgtc cattgattgc agggaacagt gcctctgact ataatggtgg aaataacggt
     6301 accatcagtg atgaaagctt tgacaacttg attgcgactg ttgaatctta tctctccaaa
     6361 gaaaaaacac gtgaagatgt tgagtctgct gtcagcaagc ttgaaagtag cacatctgag
     6421 aaatatttgg atccatctgc agtttctcgt gggtctagct tggaccgtga tgacaatggt
     6481 cttttgactc ttgctggcgg taaaatcaca gactaccgta agatggctga aggagctatg
     6541 gagcgcgtgg ttgacatcct caaagcagaa tttgaccgta gctttaaatt gatcaattct
     6601 aaaacttacc ctgtttcagg tggagaattg aacccagcaa atgtggattc agaaatcgaa
     6661 gcctttgcgc aacttggagt atcacgtggt ttggatagca aggaagctca ctatctggca
     6721 aatctttacg gttcaaatgc accgaaggtc tttgcacttg ctcacagctt ggaacaagcg
     6781 ccaggactca gcttggcaga tactttgtcc cttcactatg caatgcgcaa cgagttggct
     6841 cttagcccag ttgacttcct tcttcgtcgt accaaccata tgctctttat gcgtgatagc
     6901 ttggatagca tcgttgagcc agttttggat gaaatgggac gattctatga ctggacagaa
     6961 gaagaaaaag caacttaccg tgctgatgta aaagcagctc ttgctcaaaa cgacttagca
     7021 gaattaaaaa attaagaaaa aataaaagag gtggagggca gcattccttg tcgcccgtcc
     7081 cttcttttta atggagacag aaagatgatg aatgaattat ttggagaatt tctagggact
     7141 ttaatcctga ttcttctagg aaatggtgtt gttgcaggtg tggttcttcc taaaaccaag
     7201 agcaatagct caggttggat tgtgattact atgggttggg ggattgcagt tgcggttgca
     7261 gtctttgtat ctggcaagct cagtccagct catttaaacc cagctgtgac catcggtgtg
     7321 gccttaaaag gtggtttgcc ttgggcttcc gttttgcctt atatcttagc ccagttcgca
     7381 ggggccatgc tgggtcagat tttggtttgg ttgcaattca aaccgcatta tgaggtagaa
     7441 gaaaatgcag gcaatatcct ggcaaccttc agtactggac cagccatcaa ggatactgta
     7501 tcaaacttga ttagcgaaat ccttggaacc tttgttttgg tgttgacaat ctttgctttg
     7561 ggtctttacg attttcaggc aggtatcgga acctttgcag tgggaacttt gattgtcggt
     7621 atcggtctat cactaggtgg gacaacaggt tatgccttga acccagctcg tgaccttgga
     7681 cctcgtatca tgcacagcat cttgccaatt ccaaacaagg gagacggaga ctggtcttac
     7741 gcttggattc ctgttgtagg ccctgttatc ggagcagcct tggcagtgct tgtattctca
     7801 cttttctagt ttatactctt cgaaaatcaa attcaaacca cgtcagcgtc gccttaccgt
     7861 actcaagtac agcttgcggc tagcttccta gtttgctctt tgattttcat tgagtattag
     7921 aaaacaatta ttttgataga gcttgggcaa gagcccaatt tcagcaaaaa atgaagtaaa
     7981 tcttttcata ataaaacgca tcatatcaag cacgaaaatt ccacgaggtc aactacagtc
     8041 agaaagctga acaacaagcc aaaacgccca aaaaaggcgg caaaaagcaa gcacctgcaa
     8101 gcaacgtgcc gaaatggtca aatcctgatt atgtcaacga attagaccca aaaatcgttg
     8161 atatgctagt agaatttcac aagtcacaag gcactttgga aactcccgag gcgcaagcag
     8221 aaatcgccca aaaacgtgaa gaaatcgagc aaaggagagc tgagcttgag ggtaaaaaac
     8281 aagagctttt gaaccgcttg aacaaataga gtttcgcaag tattatgctt acaaattact
     8341 tgagcaatta actaaaatat aaaccctgcc tttatatcta ggcagggttt atattttaga
     8401 aattcacgta ggttgttacg gtttttacat acccagtata gtttgagttt ctatagtatt
     8461 cagtgataaa cttccatttt ctttgagcaa catggatata agtacttgtt atgtagtatg
     8521 gatatgggct ttgtgaatcc aagtaagact gataagcttg tataccaaaa tatgctccac
     8581 caattattgc accccatgga ccccccaata aagcacctat cctaccaatc atataactga
     8641 ttccagcacc agtcatgaag ttagcgaatg tgttagcttg tttattccca tgtattgtgt
     8701 tgacgtaatt ccaaacatta ggatcgtatg atctaaaaga tatatttagg tcgatttcat
     8761 tcttttgata agccatataa aatgccccat tgatatagac gccgtcagca cgtcgttcaa
     8821 tagtgtctac acttccatct ggattgacaa cctcaagaac ttcatcgctt aaaatattta
     8881 cttgcgtatc tccgaaccgc actgatgagc cattctcaaa ctgagcctca ccagatacaa
     8941 ctttagagtt tgccgataag ctatcatcag caaaaacaaa caagcgacgg ggaaatgcta
     9001 gacatacaga aaacagacat aactagcaaa cacatgcatt taaacatctt agacataacg
     9061 gaaactcctt tgtatttttg atttttttca acttttatta tacaataaaa ccaaataaaa
     9121 agaaagcggt aacaatatgc ttaatgcgaa aattttttat atatttttat gtttgatcgt
     9181 tatcgaaact acaggcttgt tgttgttgaa aagaggtctc gaaatgggtt atttagacac
     9241 agaagctatt atcctcgcag ttttttcatt tgctttttac aacctatgtt cattcgcttg
     9301 ggtctgctct acaataaaaa acaataaaaa ataaatagac gtattttcaa aaaaaaaaaa
     9361 tgcatattta tcttatcgaa acgacgattt aaatcgtcgt ttttttgtag tacgacgggc
     9421 atgtcgtata tctgaggtgt aagtcctcgg tgggcacctg ctaccggtga acccaatagc
     9481 gattcccaag cctgactatc gtgaggtagc agggagagga agggatagcg aaatcgtggc
     9541 tctacgaaca ggaacgtgat agtaaggcgt atatagcgga taaggaggct tcaaactcta
     9601 aagtccaaaa aggtagtcgt aacctatatg tgtaaatcac gagagtaatt gaattcggac
     9661 taaggtttgt gtgaaaaaga taaatctttc tagagtctaa agactctgcg tcagatttcc
     9721 tattttcact gtaacctttt aacgtcctca tatcttgtat acacgaggaa agatgtacga
     9781 cttatcccgt gaggtttcat gagcgctgaa agcgtagtaa caacgaatca tgagaagtca
     9841 gccgagccca tagtagtgag gaaacttctg tagtggaagt ggagcgaagg ggtgaatact
     9901 caaacagtct ggggagagac tgtttgaggt ctgtcgctag aaagagaaaa cgacagatcg
     9961 aagtaatcct acttcacttg tgtctgtaaa atgagtggtc tgatagaact ggactttgac
    10021 acgtaatgac tagatgaagg ttcaccaata taagatgtcc ctcaggcacc aaaacaagaa
    10081 aggaatacgc acatgtcaaa actgctagat aagatattat cacgcgaaaa tatgctggaa
    10141 gcctacaatc aagtaaaatc caataaaggc tcagctggga ttgatggaat gactatcgaa
    10201 gagatggata attatctcag acaaaactgg cgcttgacta aggaactgat aaaacagaga
    10261 aaatataagc ctcaaccagt tcttagagtt gagataccta aaccagacgg aggtatccgt
    10321 caactaggaa ttccaacagt tatggataga atgattcaac aggccattgt ctaagtcatg
    10381 agccccattt gtgaacccca tttctcagat acgagttatg gtttcagacc aaataggtca
    10441 tgtgaaaaag ccatcatgaa gctcttagaa tacttaaatg acggctatga gtggatagtg
    10501 gatatagacc tagagaaatt tttcgataca gttcctcaag atagattgat gtccttagta
    10561 cataacatta tcgaagacgg agatacggaa tccttgattc gtaagtatct tcattcaggt
    10621 gttatcatta atggtcaacg ttataaaaca ctagttggta caccacaggg aggaaattta
    10681 tctcctctct tatccaatat catgcttaat gaattggaca aggaattaga aaagagggga
    10741 cttcgatttg tgcgctacgc agatgattgt gtgattacgg tcgtaagcga ggcagccgct
    10801 aagcgtatga tgtattcagt cagtcgtttt attgaaaaac ggctaggttt gaaagtaaac
    10861 atgaccaaga ctaagattac cagaccaaga gagttgaaat atctaggttt tgggttctgg
    10921 aaatcatcag atggttggaa aagtcgtcca catcaagata gtgttcggag atttaagctt
    10981 aaattgaaga aactaacaca gaggaaatgg agtatagacc taacaagacg tattgagcaa
    11041 ctgaatttgt ctattcgagg atggataaac tatttctcat tgggaaatat gaaaagtata
    11101 gtcgccagca tagatgagcg cttgcgtact cgcctacgag tgattatctg gaagcaatgg
    11161 aagaagaaat cgagacgatt atggggattg cttaagttag gggttcctaa atggatagca
    11221 gataaggtat ctggctgggg cgaccattat caattagtag ctcagaagtc ggtacttaaa
    11281 cgtgctatat caaaaccagt cctggaaaaa cgtggactgg tttcgtgttt ggattattac
    11341 cttgaacgac atgcgttaaa agttagttga accgctgtat gccgaacggc acgtacggtg
    11401 gtgtgagagg ggctagagat tatcccctac tcgattaact cccctgaaat ttattttaat
    11461 tatgcaaatt tcacgtattt ttgatgctga gacgacgatc ctgggaactt ttcagatatt
    11521 tttttgacta tctaaatcta tcattagaaa agcttagagc gccaaaggat ttgagcgttt
    11581 ttctgatttt taagactttt tccagtctct ttttcgattg aagatgtaat tattctacta
    11641 actaacttct tagtactagc caacaacgat aatcataatt cctcctaaaa ttaggaataa
    11701 taaaggcaat agtttttgtt ttttcatgta aaaaacctca cttttgtttt ctgctatttt
    11761 atgctaaaat attaaaaatc aaatttaatt ccaaagtttg taactaaagg gggagcgcta
    11821 catgtctaat tcatttgtca agttgttagt ctctcaatta tttgcaaatt tagcagatat
    11881 tttctttaga gtaacaatca ttgctaacat atacattatt tcaaaatcag taattgccac
    11941 atcactagtt cctatcttaa taggaatatc ctcttttgtt gcgagtcttt tagttccgtt
    12001 ggttactaaa aggttagcgc taaatagggt tttatcttta tctcaatttg gaaagactat
    12061 attattggcg atactggtag gaatgtttac cgtaatgcaa tccgtagcgc ctttggtgac
    12121 ctatctattt gttgttgcaa tttccatact agatggtttt gcagcacccg tttcctatgc
    12181 tattgtgcca cgctatgcga ccgatttggg taaggctaat tcagccttat caatgactgg
    12241 tgaagctgtt caattgatag gttggggatt aggtggactc ttgtttgcaa caattggtct
    12301 gttacctacc acgtttatca ttttagtctt gtatatcatt tctagctttc tgatgttatt
    12361 tcttcctaac gctgaagtgg aggtgttaga gtcagaaact aatcttgaaa ttttgctcaa
    12421 aggttggaag ttagttgcta gaaatcctag attaagactt ttgtatcagc aaatttattg
    12481 gaaatttttt caaatacgat ttgggtttct tccattatac ttgtttttgt aacggagtta
    12541 ttaaataaaa cggaaagtta ctggggatat tctaatacag catactctat tggtattata
    12601 attagtggct taattgcttt taggctatct gaaaagttcc ttgctgctaa atgggaaagt
    12661 attctttttc ctcttgtagc tatggcaata gtgacactga ctattctata ttttccaaac
    12721 gcacagatgt ttttattatt ttcagcttta gttggtatgt tatcgcaact aaaagaagtt
    12781 cctgaaagtg tatttcttca ggaaacagta gaggaaaatc atttagttaa tgtctattcc
    12841 gttcttgaag tgatttctac attagcattt tcagtatttg ttttgctaat gagctatatt
    12901 actgagagtt ttggtattag catcagtttt tggctatcag ccatttgtct gatgatagaa
    12961 gctattttaa tttatatcag acgagattat tttaaatgag agagtggtta aaaagtcttt
    13021 aaaaatcaga aaagcgcata gtatcaggtg ttgaaaaaac ttgatattgt gtgttttatt
    13081 atgagaagat ttacttcatt gtctcctgaa atggagtttt gaagcaggat cactctattt
    13141 gaaaatatac atagaaaaac tgtataatcc ttaaaataag ctgaaatcta ttggaaacat
    13201 acggtaaaca attgaaaaga tactatataa agtggtacaa tggtagaaaa ataagctagt
    13261 aagaatcact cttattttag cgaaaaatta cagaaatgaa tggtttttct tgatgaaaca
    13321 gagaaaagaa ttgtacctct ttcttggtcg gacagccttg tattttctta tctttctagg
    13381 gctgctttac ttctttagct atcttggtca gggtcaagga agctttatct ataatgaatt
    13441 ttaacttgaa ggagaatccc tattgtgtca aataaaccaa tagcagatat gattgaaacc
    13501 attgagcatt ttgctcagac acagcctagc tatcctgtct ataatgtttt ggggcaggaa
    13561 cacacttatg gcgatttaaa ggctgattcg gatagtttgg ctgcagtcat tgcccaacta
    13621 ggcttgcctg agaagtctcc tgtggttgtt tttggtggcc aagaatatga aatgttggca
    13681 acctttgtag cgctgactaa gtcaggtcat gcctacattc caattgatag ccattcggcc
    13741 ttggagcgag tttcagctat tttagaagta gcagagccaa gcttgattat tgccatttca
    13801 gcctttccct tggagcaggt ttctacacca atgataaatc tagctcaggt tcaagaagcc
    13861 tttgcccaag ggaacaacta tgaaatcacg catccagtca agggagatga taattactac
    13921 attatcttta cttctggtac gactggtaag cctaagggag tgcagatttc acatgataat
    13981 ctcctcagct ttacaaactg gatgattacg gataaggaat ttgcgacacc gagtcgtccg
    14041 caaatgctgg cacagccacc ttattctttt gacttgtctg tcatgtattg ggcaccgacc
    14101 ttggcacttg gtggtacgct tttcactctt ccttcagtca tcactcagga ctttaagcaa
    14161 ctctttgcgg ctatcttttc attgccaatc gctatctgga catcaacacc atcctttgca
    14221 gatatggcca tgttgtctga atacttcaac agtgagaaaa tgcctggaat cacgcatttc
    14281 tactttgatg gtgaagaatt gacggtcaaa acagctcaaa aactgcgcga gcgtttccca
    14341 aatgcccgta tcatcaatgc ttacggccca acagaagcga cagtagctct gtcagcagtt
    14401 gccgtgacag acgagatgtt agcgactctc aaacgcctac caatcggcta taccaaggct
    14461 gattctccaa cctttatcat tgacgaggaa ggaaataaac tgccaaatgg tgagcaggga
    14521 gaaatcattg tttctgggcc agctgtttca aaaggttata tgaaaaatcc tgaaaaaaca
    14581 gcagaagcct tctttgagtt tgaaggtctg ccagcctatc acacaggcga tgtgggaacc
    14641 atgacagatg agggcttgct tctctacggc ggacgcatgg acttccagat taagtttaac
    14701 ggttaccgca ttgagttaga agatgtctct caaaacctca acaagtctcg ctttatcgaa
    14761 tctgctgtcg cagtaccgcg ctataacaag gaccacaagg tacaaaatct attggcttat
    14821 gtcatcttaa aagacggtgt tcgtgagcag tttgagcgag atatcgatat taccaaggcc
    14881 atcaaggaag acctgacaga catcatgatg tcctatatga tgccatctaa attcctttac
    14941 cgagacagtt tgccactaac tccaaatgga aagattgaca tcaaaggatt gattaacgag
    15001 gtgaataaga gatgatggag ttttttcaac agcttcctca tttagagcca tatggcaatc
    15061 ctcagtattt tgtttatgtg attgctgcaa ccttgcccat ctttataggt ctctttttca
    15121 agaaacgctt tgcctggtat gaagtgttgg taagtctctt ctttattgtc accatgttgg
    15181 tgggtggaaa gaccaatcaa ctagctgcct tgggtattta cctttgctgg gaaatattgc
    15241 tcctgctttt ctacaagcat tatcgaaaaa gcaaggatgg caagtgggtc ttctacttag
    15301 ttagttttct gtccctactt ccgattatct ttgtcaaggt gcaaccagct atcaatggaa
    15361 cgcagtcttt gcttgggttc ttgggaattt cttacctgac ctttcgttcg gttgggatta
    15421 tcatcgagct gagagatgga gtgattaagg attttaccct ctgggaattc ctccgtttcc
    15481 ttctcttcat gccaactttc tcgagtggtc caatcgatcg ctttaagcga tttaatgaaa
    15541 attatcaggc cattcctgag cgagatgagt tgatggatat gctggatgaa tctgtccgct
    15601 atatcatgcg gggctttttg tataagttta tcctagctca tgttttagga gagaccttac
    15661 tacctcctct gaagaattta gccttgcagt caggtggctt ctttaatctc tatgccttgg
    15721 cagttatgta tacttttggt ctggaactct tctttgactt tgcaggttat tctatgtttg
    15781 ctttggccat ctcaaacttg atgggaatcc gtagccctat caactttaac aagccctttt
    15841 tatcaaggga tttaaaggag ttttggaatc gctggcatat gagtctgtcc ttctggttcc
    15901 gtgactttgt ctttatgcga atggtgatgg tgttaaccag aaagaaagtc tttaaaaatc
    15961 gtaatgtaac ctcaagcatg gcctacattg taaatatgct gattatggga ttttggcatg
    16021 gtgtgacctg gtactatatc gcctatggac tctttcatgg actaggcttg gtcatcaatg
    16081 atgcctgggt tcgcaagaaa aaaacgctca ataaggaacg gaaaaaagca gggaaggctg
    16141 ccctacctga gaatcgctgg attcagttgc ttggcatggt tgtcactttc catgttgtca
    16201 tgttgtcatt cttaatcttt tctggattct tgaataatct atggtttaaa aaataaaagg
    16261 aaataaaata tggatatcaa atcagaagtt attgaaatta ttgatgagtt gtttatggaa
    16321 gatgtttctg acatgatgga tgaagatctt tttgatgcag gtgtcttgga tagtatggga
    16381 acggttgagt tgattgtgga gattgagaac cgttttgaca ttcgtgtccc tgtaacagag
    16441 tttggtcgtg acgactggaa tacagctaat aaaatcatag ctggtattgt ggagctacaa
    16501 aatgcttaaa cgcttatgga tgatcttcgg accggtcttg atcgctggtt tgttggtttt
    16561 tctgctcatt ttcttttatc ctactgagat gcatcataat ctaggagctg aaaagcgttc
    16621 agcagtggct actactatcg atagttttaa ggagcgaagt caaaaagtca gagcactatc
    16681 tgatccaaat gtgcgttttg ttcccttctt tggctctagt gaatggcttc gttttgacgg
    16741 tgctcatcct gcggtattag ctgagaaata caatcgttcc taccgtcctt atcttttagg
    16801 acagggggga gctgcatcgc ttaaccaata ttttggaatg caacagatgt taccacagct
    16861 ggagaataaa caagttgtgt atgttatctc acctcagtgg ttcagtaaaa atggctatga
    16921 tccagcagcc ttccagcagt attttaatgg agaccagttg actagttttc tgaaacatca
    16981 atctggggat caggctagtc aatatgcagc gactcgctta ctgcaacagt tcccaaacgt
    17041 agctatgaag gacctggttc agaagttggc aagtaaagaa gaattgtcga cagcagacaa
    17101 tgaaatgatt gaattattgg ctcgttttaa tgaacgccaa gcttcctttt ttggtcagtt
    17161 ttcggttaga ggctatgtta actacgataa gcatgtagct aagtatttaa aaatcttgcc
    17221 agaccagttt tcttatcagg caatagaaga tgttgtcaaa gcagatgctg aaaaaaatac
    17281 ttccaataat gagatgggaa tggaaaatta tttctataat gagcagatca agaaggattt
    17341 gaagaaatta aaggattctc agaaaagctt tacctatctc aagtcgccag agtataatga
    17401 cttgcagttg gttttaacac agttttctaa atctaaggta aacccgattt ttatcattcc
    17461 acctgttaat aaaaaatgga tggactatgc tggtctacga gaggatatgt accaacaaac
    17521 ggtgcagaag attcgctacc agttagaaag tcaaggtttt accaatatag cagatttttc
    17581 taaggacggc ggggagcctt tctttatgaa ggacaccatt caccttggtt ggttgggttg
    17641 gttggctttt gacaaggcag ttgatccttt cctatccaat cccacaccag ctccgactta
    17701 ccatctgaat gagcgctttt tcagcaaaga ttgggcgact tatgatggag atgtcaaaga
    17761 atttcaatag ataatataat atagaagagt tcaagaatga aactagtttt cacgtttttt
    17821 cttgactctt tttttgcttg tgatataatt aactggtaaa caaaatgtca aagaatagta
    17881 tttttctctt aaaaaagaga agtctaaaag gaaaggagtc agatatgaga cagctagcaa
    17941 aggatatcaa tgcttttttg aatgaggtga ttttgcaggc ggaaaatcag catgaaatcc
    18001 taataggtca ttgcactagc gaggtggccc tgaccaatac tcaggagcat atccttatgc
    18061 tcttgtcaga ggaatcttta acaaattcag aattggctcg tcgtctcaat gtcagtcagg
    18121 cggcagttac caaggccatt aagtctttgg tcaaggaagg gatgttggaa acatctaaag
    18181 attctaaaga tgcgcgtgtg attttttatc agttgactga cttggctcgt ccaatcgctg
    18241 aggagcacca ccatcaccat gagcatacac ttttaaccta tgaacaagtg gcgactcagt
    18301 ttactccaaa tgaacaaaaa gtgattcagc ggtttttgac tgctttagta ggagaaatca
    18361 aataatgaga tatattacgg tagaggattt gtccttctat tatgataagg agcctgttct
    18421 tgaacatatc aattatagtg ttgatagtgg ggaatttgtt accttgactg gggaaaatgg
    18481 agcggctaag acgacgctca tcaaggctag tcttggaatt ctgcaaccac gcattggaaa
    18541 ggtggctatt tcaaagacaa atacgcaagg taagaaattg agaatagcct atcttcctca
    18601 acaaattgcc agttttaatg ctggttttcc aagtacggtc tatgaatttg tcaagtcggg
    18661 tcgctatccg agaaaaggct ggttccgtcg tttgaatgct catgatgagg agcatatcaa
    18721 ggctagtctg gactcagttg gcatgtggga acatcgagac aaacgcttgg ggtctctatc
    18781 tgggggacaa aagcagcgag cggtgattgc gcgtatgttt gcttctgacc ctgatgtgtt
    18841 tatcctagac gagccgacaa cggggatgga tgcaggaagt aaaaatgaat tttacgaact
    18901 catgcaccac agcgcccatc atcatggcaa ggctgttttg atgattaccc atgaccctga
    18961 agaagttaag gattatgcgg atcgcaatat tcatctagtc cgtaaccaag actcgccatg
    19021 gcgttgtttc aacgttcatg agaatggcca ggaggtgggc catgcttagt ttattatctt
    19081 atgactttat acaacgcgcc tttttggcgg ttattgctat gagtcttttc tcaccggtat
    19141 tgggaacctt cctcatcttg cgtcgtcaga gtttgatgag tgataccctt agccacgtct
    19201 cactttcagg tgtagccttt ggtctggttt tggggatttc tccaactgtt tctactattg
    19261 ccattgtctt gattgcggcg gtctttctgg agtatctccg tacggtttac aagagcttta
    19321 tggaaatcgg gacagctatc ctcatgtcaa caggtttggc tgtttctctg attgtcatga
    19381 gcaagggtag aagctcgagt tcaatgagtt tggaccaata tctctttggt tcgatcgtga
    19441 ctatcagtga agaacaggtc atttccctct ttgtcattgc ggcggttgtt ttgattttga
    19501 cctttctctt tcttcgtcct atgtatatct taacttttga tgaagatacg gcctttgtgg
    19561 atggcttgcc agttcgtacc atgtccattc tttttaacat ggtgacaggg gtggctattg
    19621 cccttatgat tcctgcagca ggagctcttc tggtatcgac cattatggtc ttgccagcta
    19681 gtattgccct gcgtctgggg aaaaacttta aatcggttat gctgcttgcc agtgcgattg
    19741 gctttttggg aatggtagca ggactttaca tttcctacta tgcagaaaca cctgcaagtg
    19801 caagtattac cattattttt gtaactgtct ttatactaat cagtttagta agacgtttta
    19861 tcaaatagga gacgaacgtg aaaaaaatta gcttattact agccagtcta tgtgccttgt
    19921 ttttagtggc ttgttccaat caaaaacagg cagatggtaa actcaatatc gtgacaacct
    19981 tttaccctgt ctatgaattt accaagcaag tcgcaggaga tacggctaat gtagaactcc
    20041 taatcggtgc tgggacagaa cctcatgaat acgaaccatc tgccaaggca gttgccaaaa
    20101 tccaagatgc agataccttc gtttatgaaa atgaaaacat ggaaacatgg gtacctaaat
    20161 tgctagatac cttggataag aaaaaagtga aaaccatcaa ggcgacaggc gatatgttgc
    20221 tcttgccagg tggcgaggaa gaagagggag accatgacca tggagaagaa ggtcatcacc
    20281 atgagtttga cccccatgtt tggttatcac cagttcgtgc cattaaacta gtagagcaca
    20341 tccgcgacag cttgtcagca gattatcctg ataaaaaaga gacctttgag aagaatgcag
    20401 ctgcctatat cgaaaaattg caagccttgg ataaggctta cgcagaaggc ttgtctcaag
    20461 caaaacaaaa gagctttgtg actcaacacg cagcctttaa ctatcttgcc ttggactatg
    20521 gactcaaaca agtcgcaatc tcaggacttt ctccagatgc agagccatca gctgctcgct
    20581 tggcagaatt gacagagtat gtcaagaaaa ataaaatcgc ctatatctat tttgaagaaa
    20641 atgcctcaca agcccttgct aacacacttt caaaagaagc aggtgtcaaa actgatgtcc
    20701 tcaatccttt agaaagtctg acagaagagg acaccaaggc tggagaaaac tacatttccg
    20761 tgatggagaa aaacctcaag gctttgaaac aaacaacaga ccaagaaggc ccagcaatcg
    20821 aacctgaaaa ggcagaggat accaagacag tcccaaatgg ttacttcgag gatgcagctg
    20881 tcaaggaccg caccttgagt gactatgcag gtaactggca atcagtttat cctttccttg
    20941 aagacggcac gtttgaccaa gtctttgact acaaggctaa gttgactggt aagatgaccc
    21001 aggctgagta caaggcttac tatacaaaag gctatcagac agatgtgact aagattaaca
    21061 ttactgataa tactatggaa tttgttcaag gtggacaaag caagaaatac acttacaagt
    21121 atgtcggtaa gaaaattttg acttacaaga aaggcaatcg tggcgtgcgt ttcctctttg
    21181 aagccacaga tgctgacgct ggacaattca agtatgttca gtttagtgac cacaatgttg
    21241 ccccagttaa ggcagaacat ttccatatct tctttggagg cacaagccaa gaagccctct
    21301 ttgaagaaat ggacaactgg ccaacctact acccagataa cctatctggc caagaaatcg
    21361 cccaagaaat gttggcgcat tgatgagaaa tcgactagtt cataagagct agtcggtttt
    21421 ttgatactag atggctaact tcattataga cctttcagaa ctttaaacaa taaataaaac
    21481 tcttgaaata tctgggctta tatgctagaa tgtagttagt gtataaggtt cattagaaca
    21541 ccaaagcccc taactagtgc catagttaag ggcttttttg acgtatctta gcgatttaac
    21601 gggtgtttat aggctagtca ttcggtctac ttcttaccat ctagccattt gcagacgaaa
    21661 tacaagataa ttccagctat aacatctgct ataatagtaa gagcaagctc tggtataagg
    21721 ctcattagtt tcacctcctc tcacgaaccg taaggaacgt aatcggtaac cgatgacaaa
    21781 aatagtatat cacactacat tcaggtcatc aaccttactt aatgcttgaa ctattgtaga
    21841 ttatatgcta gaatgtagtt aattgataag gttcattaga acaccaaagc ccctaactat
    21901 ggccgtagtt aagggctttt ttgacgtatc ttagcgattt aacgggtgtt tataggctag
    21961 tcagtcggtc tactccttac tatctagcca tctgcagacg aaatacaaga taattccagc
    22021 tataacatcc gctataatag taagagcgag ctctatgata aggctcatta gtttcacctt
    22081 ctctcacgaa cccataggaa cgtaatcggt aaccgatgac aaaaatagta taccacaata
    22141 aatttagatc atcaaggtca cttaattctt gaaatatagg gtctaggcga caaagtcttt
    22201 aaaatcagaa aaacgcataa tatcaggttt gcaaaaactt gatactatgc gttttattgt
    22261 gggaaggttt actccatttt ctcctgaaat tgagtttttg tccagcctct gtttttagaa
    22321 ttgctaagaa aataatgtca tgtggtgaat atttgtaaat cagtcagcag acagaacgaa
    22381 tactcttcga aaatctcttc acatcatgtc agcttcgtct tgccgtgtcc atgggggact
    22441 tgacttcatc agttttcaaa tctgtacttt gagcaagctg agactagctt cctatttgat
    22501 tttcattgaa tatcagaaac ccattctcca tcaaataatt cgactgcgtc taataatttt
    22561 tgatttggca aggtgtcaga aataaaggtt gtgtatttgg agaggggatt aattttaaaa
    22621 aatccagtct tgtaaaattt agaactatca atcagtaaga tggtttcatg ggctttgtca
    22681 ataatattct tttttgaaat agcttggctg agagaagctt cataaacata ttggtcatca
    22741 atacctcttg ctgaacaaaa tgctaaatcg atattaaaat gatctaataa agaattttcc
    22801 ttatcatagt tgaccacgga acaggattga tgtttgacct cgccagatgt gataaagatt
    22861 ttggagctat ctttaacagt ttcagatagg gtttgtgcag tatgtaaacc atttgtaaaa
    22921 ataatcaaat tatcaagttc agaaagatag ggacaaagtt cgtagacagt cgtactggaa
    22981 tccagataaa tacacatgcc tgaccgaata aagtctttag cgagactagc gattagtctt
    23041 ttttgcctag tactttctcc ttcccgtatt tgatgagaaa gttcaattgt gttcatagag
    23101 gacagggtca cgtatccgtg ctttcttttg ataagacctt gattttctaa gaaaattaaa
    23161 tcacgacgta aggtacttgt gctggagaaa gtgatttctg ccagctcttt tacggcaatt
    23221 ctttttttct ttttaataat ttcaatcaat tcaagtacac gttcatcttt tatcataagc
    23281 tcctcctaat ttatcatttc aactatatta tagcacaaat tggaggaatg tgaattattt
    23341 ttatgaatat tgggttaaca tttgaacatt attcaagtaa gcgttcacat attgaaaaaa
    23401 taaaacgtgg ggattataat aaagttaatc aaggacgaag agagaagaaa aatggaagcg
    23461 gttttagcaa tagatttagg tgcgacttct ggaagagcaa tcgttggtta cctttctgaa
    23521 aataaactgg taatggaaga aataaatcgc ttttctaatc tacctattag agtaaaaggg
    23581 catttatctt gggatattga ctttctacta gctaaaattc ttgaaagtat ccgcttggct
    23641 aatactagtt acaagatttt atctatcggt attgacacat ggggagttga ttttggactg
    23701 attgataatg aaggtaagct gttattacaa cctgttcatt atcgtgatga aagaacaaag
    23761 ggagtgttaa aggaaatatc tgaaatgact gaattagaaa aactgtattc agagacagga
    23821 aatcagatta tggagataaa taccttgttt caactcttta aggcacgtca agaatctcct
    23881 gactctttct ataagaccaa taagattctt ttaatgccag atttgtttaa ttatctcttg
    23941 acaggtaagt tttctacaga aaaaagcatt gcttcaacaa ctcaattatt tgatcctagg
    24001 agtcaaaatt ggaatcagaa tatcttaaaa ctatttgaat tggattcatc tttacttcct
    24061 gaaattgttt cagagggaaa tgttcttgga aggataaaaa aggagtatgg tttaggcgat
    24121 attcctgttg tgaatgtttg tagtcatgat acagcaagtg cgattgtctc agtacctaag
    24181 acagaaggta gtttatttat ttcatcaggt acttggtctt tggttggagt ggaacttact
    24241 tcaccgattc ttactaccga atccttcagt tatggattta caaatgaagt cggtaaagat
    24301 ggagagatta catttctgaa gaattgtaca gggttgtgga tcatagagga actaagacgt
    24361 tcatttgaac gaagagggaa agcctattct tttgatgata ttaggacaat ggtggagaaa
    24421 gaaaaagaaa atcttcctct gattgatact gaatcaactg aatttgcaac agaatctgat
    24481 atgcacaaga ctttgacaga atatctagct tatcatcatg aaactagaga gtggacagat
    24541 ggacaactat ttaagattgt ttatgaaagc ctagctgaaa cgtataggaa agcgatagag
    24601 ttactagaag aactaactca taaggtttat aagaggatat atgtgattgg aggaggtgct
    24661 agagccagtt actttaacca aatgattgct gatagaactg gtaaagaggt tcttacaggt
    24721 tcgactgagg gtacagctgt ggggaatatt gttgtgcagc tcatagctat gggacaatta
    24781 aaagggatgg aagaagctca ccatgttatt gaggagtttc tacaattaga gagttattac
    24841 tcccaaaaga attaaaaaga ttgagagttt gtaaatttgc ctccctcccc cttcttaagt
    24901 tttgtacaag aaggggggat aattggtgaa ttgaaaaata tttagtgttt tgatatgagg
    24961 aggacaagaa tgtcagatgt aaaacaagaa ttaattaagt atggcaagaa gctagtagaa
    25021 acagatttga cgaaaggaac aggtgggaat ctcagtgttt tcgatcgtga aaaacaattg
    25081 atggcaatta ccccgtcggg tattgatttc tttgaaatca aagaatccga tattgtagtg
    25141 atggatatta atggaaatgt tgtagaggga gaacgcttgc catctagcga atggtatatg
    25201 catttgattc aatatcaaac tcgtgatgat atcgatgcaa ttatccatgc tcatacaact
    25261 tatgcaacag tattagcttg tctcagagaa ccacttccgg ctagtcatta tatgattgca
    25321 gtggcaggga aagatgttcg ggtagctgag tatgcaacat atggtacgaa agaattggct
    25381 gtgaatgcag ctaaagcaat ggaaggtcgt agagcagttt tactagcgaa tcatggaatt
    25441 ttagcaggtg cacaaaattt attgaatgca tttaatattg ttgaagaagt tgaatattgt
    25501 gcaaaaattt attgtttagc taagaatttt ggagagccag tagttcttcc tgatgaggag
    25561 atggatttaa tggcagaaaa atttaaaaca tacggtcaga gaaaataggg aggatattaa
    25621 tgttaaaaca tataccgaaa aatatttctc cagatttatt gaagacttta atggaaatgg
    25681 gacatggaga tgaaatagta ttagctgacg cgaattatcc ttctgcctca tgtgcaaata
    25741 agctaattcg ttgtgatggc gtaaatattc cagaattatt agattccatt ctgtatttaa
    25801 tgccattaga tagttacgtc gatagttcaa ttcagtttat gaacgttgtt tcgggtgatg
    25861 atattcctaa gatatggggt acctatagac agatgattga aggtcatggt acagatctta
    25921 aaacgattac ttatcttaga agagaagact tttatgaacg tagtaagaaa gcttatgcta
    25981 ttgttgctac aggagaaact tcactttatg ctaatattat ccttaagaaa ggagtagttg
    26041 ttgaaagaga aaatgtttaa tagaggaatt ttagttgcca gtcatggtaa ttttgctagc
    26101 ggagctctca tgaccgcaga aatgtttgtt ggtgagacaa caaatgatag agttaggaca
    26161 ttaggtttga tgcctggaga gaatattgta gagtttgaac attattttaa aaatcaagta
    26221 aatgaactgt tagactcaaa tcaagaggtt atcgttttga ctgacttgat tggaggaagt
    26281 cctaataatg tggctttgtc acggttttta aatttggatt cagttgatat tgtaacaggg
    26341 tttaatatcc ctctcctagt ggaattaata tcaagttatg attcaaaaat caatttagaa
    26401 gaaattgttc aaaatgctca aaatagtttg tttaatgtta aacaacaact taacgtagag
    26461 gaggaagagg atttatgtct atagagtttg ttcgtattga tgaccgtctg gtacatggtc
    26521 aagttgtcac tacgtggcta aaaaagtatg atattgagca agttatcatt gttaatgatc
    26581 gcatctcaga agataaaaca cgacaatcta ttttaaagat ttctgcaccg gtaggtttaa
    26641 aaattgtttt ctttagtgta aaacggtttg tggaagtttt aaactctgtg ccaataaaaa
    26701 agagaacaat gctgatatat acaaatccaa aagatgtgta tgattctatt gaaggaaatt
    26761 taaaattgga gtacctcaat gtaggacaga tgagtaaaac ggaggaaaat gaaaaggtaa
    26821 cgggaggtgt agctctaggt gaagaagaca aatattattt taagaaaata gttgataagg
    26881 gaacgagagt tgaaattcaa atggttccta atgataaagt tacaatgttg gaaaaatttt
    26941 tataaaaata atttaaggag gtacagtata tgctattcac acaagcatta ctggtgacat
    27001 tagttgggat tattgccact attgactata atggaccgtt atttatgatt caccgtccgt
    27061 tagttacaag tgcaatggtt ggcttagtct taggagattt cacccaaggt gttcttattg
    27121 gttcagctct tgaattaact tggctcggtg taacaggtat tggaggttac actccaccag
    27181 atactatttc aggtgcgatt attggtactg catttggtat tttgtctggt caaggagaaa
    27241 ctgctggtat cgctatagca gttccaattg cagttgctac tcaacagttg gatgttcttg
    27301 caaaaacttt agatgtttat tttgtgaaaa aagctgataa tgatgctaaa aacggagatt
    27361 attcaaagat cggtttttat cattattcaa gtttggtttt aatcacttta tttaaaattg
    27421 taccaatttt cctagctatt atgcttggag gggaatatgt ggcagacttg tttgctaagg
    27481 ttccaccaat cgttatgcag ggacttaact ctgcaggtgc tttactacct tcaattggtt
    27541 ttggtatgct tttaaatatg atgctcaaga aaaatatgtg ggtattcttg ttgattggat
    27601 tcatttgttc tgtgtatgga ggaatgtcaa ccattgggat ctcactagtt ggtattgcgg
    27661 tagcatactt ctacgatatg attggaagta aaccacaaga aacaacttca agtagtgatg
    27721 ttgaggagga tcttgatcta tgatgaataa taaagtaact aaagttgaac ttaaaaaagt
    27781 tttcaaacga agttttatgt atggttcttc atggaactat gagagaatgc agaacctagg
    27841 ttttctatat acaattcttc cagtattgaa aaaactatac ccagacaaag attcagcttc
    27901 tcctgcaatg aaacgtcacc ttgagttttt caatactcat caaacagcgg caccatttat
    27961 tcttggagtt acttccgcta tggaagaaca agaaggaaat gaaggtgcag cttcaattac
    28021 tggtattaaa gttggcttga tggggccact ggctggtcta ggagatagtt tgttctggct
    28081 gacactagtt cctatctgtt ttagtattgg tgcgtcttat tctaaagacg gcggtgcttt
    28141 aggtatcttt atcgccttaa tattgtttaa tattattaat attcctgtta aatatttcgg
    28201 tttgaaatat gggtatacta agggttctag tcttatccaa gaaaataata caaaaggaac
    28261 attgaatcgc gttacgagta tggcgacagc attagggcta gtactagtgg gtggtttgat
    28321 tccatcaatg gttggtatta attttggatt agaatttaag cagggggaac ttgttatttc
    28381 tgttcaagaa atgattacaa aattaattcc aggatttatc cctatggctt tgactttatt
    28441 aatgtgtaaa ttaattagaa aaggaaagaa tccggttgta ctaatcttta gtgttatggc
    28501 tattggagtt atcctagttg ttttaggaat tttgaagtag tagaaagtgt ggaggtggta
    28561 tttgggatat cacctccatt ttggaagaga ggtaaagagt gaaattatgg tataagaaag
    28621 ctgccgcaaa ttggaatgaa gccttgccga ttgggaacgg tcatttaggt ggtatgattt
    28681 atggttcagc tacaaaagaa tgtattcaac taaacgatga gactatttgg tatagaggaa
    28741 agtcagatag aaataatcca gactcactat tgcatcttaa aaaaattcgg gaatatcttt
    28801 tagatggaga aattcagaaa gccgaagaat tgataaagtt aacaatgttt gctaccccaa
    28861 gagatcaaag ccactatgaa ttacttgggg aactttgcat tgagcatata gatattcagt
    28921 cttgtgctct ttcattgtat gaaagagagc tagatttaga tacagctatt tctaatgttg
    28981 tgtttgagcc taatagttgt aatttacaaa taaaaagaga atattttacg agttttaata
    29041 agaatatttt atgttgccgt atagtgtcat cagttcaaaa cacattaaat ttaaacatta
    29101 atttgggtag aaataaacgg tttaatgacg aagtatctaa actggattca agtacaattt
    29161 taatgtcggc ctctgctgga ggtagaaaag gtgttcagtt taaagtagta tgtcattcta
    29221 aggttacgga tggtgaagta agtgtattgg gagagacaat agttattcgg aatgctacag
    29281 aggtatttct ttatctcaaa tcaatgacgg attattgggg aaatatagat atttcttctc
    29341 ttcagggaga atttagtagt attgattact ttacagaaaa agatgaacat gtaaaaaaat
    29401 atcaggagca atttaataga gttgatttta aactagacta tagtaaaggt tgtcttagca
    29461 ttccaacgaa tctacttctt gaaaacacta aaaagtatag taactacttg actaacttgt
    29521 tatttcatta tggaagatat ctgttaatat cgtctagtca accgaatggt ttacctgcca
    29581 atcttcaagg aatatggtgt gatgaattaa atccaatttg gggttctaaa tatacgatta
    29641 atattaatac tcaaatgaat tattggatgg taggtccatg tgatttacca gaagtagaat
    29701 atccattatt tgatatgctc gaaagaatga gagaaccggg aagactaacc gctaagaaaa
    29761 tgtatggagc tagaggtttt acagcacatc ataatacgga tggttttggc gatacggctc
    29821 cccaatctca tgccatgggg gctgcaattt gggtattaac tattccatgg ttatgtactc
    29881 atatttggga acactattta tatttccaag atgagcgtat tcttacggaa cattttgaaa
    29941 tgataaaaga agcatttctt ttctttgaag attatttatt tgaggtggat ggctacttga
    30001 tgacaggtcc aagtgtctca ccggaaaata aatatcgctt aaaaaatggt attgaaggaa
    30061 atgcttgtct atcatctaca attgataatc aaattctaag atatttttgt gattcatgca
    30121 ttggcattgc aaaacaatta ggagacaatt cggattttat tagtcgtgtg aaggagttaa
    30181 aaaagaaatt acctagaaca aaaataggta gtaatgggca aatacaagaa tggctagagg
    30241 attatgaaga agtagagcct ggtcatagac acatttcacc tctatttggg ctttatcctt
    30301 ataatgagat tgatattcat aaaactccgg aattagcaga agcagctaaa atcactatca
    30361 ataggagatt atcaaacgct aactttttat cttcacagga tagggagcaa gcgattaata
    30421 attggttagt aagtggtttg catgctagta cacaaacagg ttggagtgct gcatggctga
    30481 ttcatttttt tgcgagacta tatcaaggtg aacctgctta taaccagatt aatggtttgt
    30541 taaataatgc gactcttggc aatttatttc ttgaccatcc accatttcaa attgatggta
    30601 atttaggttt ggtgagtgga atttgtgaat tattagtaca gagccatcat aattggttat
    30661 cactaattcc agctttacct tctgcttggt cagaaggaga agtgaaaggt ttcagagtaa
    30721 gaggaggata taaggtatcg tttgcttgga aaaatgggga tataacattc ctaaaattgg
    30781 aaggaggaaa caaagatcaa aaagtaagag taagaatata tggcaaaaat actgatgtac
    30841 aaaatattga attggtattt aattcagaaa aaattattga gttaaatttt taggtataag
    30901 tcatgaataa agaaaaaata aaaagaaaat taatcacaat actgtttgta tgtattggga
    30961 tgttatgttt tggattgtta gcaggagtta aggctgataa tcgtgttcaa atgagaacga
    31021 cgattaataa tgaatcgcca ttgttgcttt ctccgttgta tggcaatgat aatggtaacg
    31081 gattatggtg ggggaacaca ttgaagggag catgggaagc tattcctgaa gatgtaaaac
    31141 catatgcagc gattgaactt catcctgcaa aagtctgtaa accaacaagt tgtattccac
    31201 gagatacgaa agaattgaga gaatggtatg tcaagatgtt ggaggaagct caaagtctaa
    31261 acattccagt tttcttggtt attatgtcgg ctggagagcg taatacagtt cctccagagt
    31321 ggttagatga acaattccaa aagtatagtg tgttaaaagg tgttttaaat attgagaatt
    31381 attggattta caataaccag ttagctccgc atagtgctaa atatttggaa gtttgtgcca
    31441 aatatggagc gcattttatc tggcatgatc atgaaaaatg gttctgggaa actattatga
    31501 atgatccgac attctttgaa gcgagtcaaa aatatcataa aaatttggtg ttggcaacta
    31561 aaaatacgcc aataagagat gatgcgggta cagattctat cgttagtgga ttttggttga
    31621 gtggcttatg tgataactgg ggctcatcaa cagatacatg gaaatggtgg gaaaaacatt
    31681 atacaaacac atttgaaact ggaagagcta gggatatgag atcctatgca tcggaaccag
    31741 aatcaatgat tgctatggaa atgatgaatg tatatactgg gggaggcaca gtttataatt
    31801 tcgaatgtgc cgcgtataca tttatgacaa atgatgtacc aactccagca tttactaaag
    31861 gtattattcc tttctttaga catgctatac aaaatccagc tccaagtaag gaagaagttg
    31921 taaatagaac aaaagctgta ttttggaatg gagaaggtag gattagttca ttaaacggat
    31981 tttatcaagg actttattcg aatgatgaaa caatgccttt atataataat gggagatatc
    32041 atattcttcc tgtaatacat gagaaaattg ataaggaaaa gatttcatct atattcccta
    32101 atgcaaaaat tttgactaaa aatagtgagg aattgtctag taaagtcaac tatttaaact
    32161 cgctttatcc aaaactttat gaaggagatg ggtatgctca gcgtgtaggt aattcctggt
    32221 atatttataa tagtaatgct aatatcaata aaaatcagca agtaatgttg cctatgtata
    32281 ctaataatac aaagtcgtta tcgttagatt tgacgccaca tacttacgct gttgttaaag
    32341 aaaatccaaa taatttacat attttattga acaattacag gacagataag acagctatgt
    32401 gggcattatc aggaaatttt gatgcatcaa aaagttggaa gaaagaagaa ttagagttag
    32461 cgaactggat aagcaaaaat tattccatca atcctgtaga taatgacttt aggacaacaa
    32521 cacttacatt aaaagggcat actggtcata aacctcagat aaatataagt ggcgataaaa
    32581 atcattatac ttatacagaa aattgggatg agaataccca tgtttatacc attacggtta
    32641 atcataatgg aatggtagag atgtctataa atactgaagg gacaggccca gtccctttcc
    32701 caacaccaga taaatttaat gatggtaatt tgaatatagc atatgcaaaa ccaacaacac
    32761 aaagttctgt agattacaat ggagacccta atagagctgt ggatggtaac agaaatggta
    32821 attttaactc tggttcggta acacacacta gggcagataa tccttcttgg tgggaagtcg
    32881 atttgaaaaa aatggataaa gttgggcttg ttaaaattta taatcgcaca gatgctgaga
    32941 ctcaacgtct atctaatttt gatgtgattc tatatgacaa taatagaaac gaagttgcta
    33001 agaaacatgt taataatttg tcgggtgaat ctgttagtct agatttcaaa gaaaaaggag
    33061 caaggtatat taaagttaaa ttactaacga gtggagtgcc tttgagttta gcagaagtag
    33121 aggtttttag agaatcagat ggtaagcaat ctgaagagga tatagataaa ataacagaag
    33181 ataaagtagt ctctacaaat aaggtagcta ctcaaagttc aaccaattat gagggtgtag
    33241 ctgctttagc agttgatggt aataaagatg gagattacgg acatcattcg gtgactcata
    33301 ctaaggcaga ttctaacgct tggtggcagg tcgatctggg agaagagttt acggtttcta
    33361 aagttgatat ttataataga acagatgccg aacctcagcg tttatctaat tttgatgtta
    33421 tttttctatc ttcatcagga gaagaagttt ttagaagaca ttttgataaa gtagttgatg
    33481 gtttgttatc tttaaaagta ccttctgtag gggctaagct agtcaaaata gaattaaaat
    33541 cagcagctat tccgttaagt ttagcggaag ttgaagtcta tggttcaaag agaactccga
    33601 agaaactttc taatattgca ttaaccaaag aaactcgaca gagttcaacg gattacaatg
    33661 gtttttctcg tctagcagtt gatggaaata aaaacggaga ttatggtcat cattcagtga
    33721 ctcataccaa aggagattct ccttcatggt gggagataga tttagcacaa accgaagaat
    33781 tagaaaagtt aattatttat aatagaacag atgctgaaat tcagagatta tcaaattttg
    33841 atattattat atatgattca aataatcatg aagtttttaa acaacatatt gacagtttag
    33901 aaagcaataa tctatccata gacttaaaag ggctgaaggg aaaaaaggtt agaatttctt
    33961 tgagaaacgc aggaattcct ttaagtttgg cagaggtaga ggtttatact tataagtaat
    34021 tttaaaaatt atcatcggta gtatgaaaga aacagaaaaa taagaggaaa atagtatgat
    34081 tcaacatcca cgtattggga ttcgtccgac tattgatggt cgtcgtcaag gtgtacgcga
    34141 atcacttgaa gtacaaacaa tgaacatggc taaaagtgtg gcagatttga tttcaagcac
    34201 attgaaatat ccagatgggg aacctgtgga atgtgtgatt tctccatcta ccattggtcg
    34261 tgttccagag gctgcagctt cccatgagtt gttcaaaaaa tcaaatgttt gcgcaacaat
    34321 tacagttaca ccatgctggt gttatggtag tgaaactatg gatatgtctc cagatattcc
    34381 tcatgctatt tggggattta atgggacaga acgcccagga gctgtctatc ttgcagctgt
    34441 actagcttca catgctcaaa aagggattcc agcctttggg atttatggta gagatgttca
    34501 ggaagctaat gatacagata ttccagaaga tgtcaaagaa aaacttttac gttatgcgcg
    34561 tgcagctctt gcaactggct tgatgagaga cactgcttac ctatcaatgg gtagtgtttc
    34621 gatggggatt ggcggttcta ttgtaaatcc agatttcttc caagaatact taggaatgcg
    34681 aaatgaatcg gtagatatga cggagttcac gcgccgtatg gaccgtggta tttatgaccc
    34741 agaagagttt gaacgtgcgc tcaaatgggt gaaagaaaac gtaaaagaag gattcgacca
    34801 taaccgtgaa gaccttgttt taagccgtga agaaaaagat agacaatggg aatttgttat
    34861 taagatgttc atgattggac gtgacttaat ggttggtaac ccaagacttg ctgaacttgg
    34921 ttttgaggaa gaagcagttg gtcaccatgc tttagtagct ggtttccaag gtcaacgtca
    34981 gtggacagac cattttccaa atggagattt tatggaaact ttcctcaata ctcagtttga
    35041 ctggaatggt attcgaaaac catttgtatt tgcgacagag aatgattcac taaatggtgt
    35101 gtctatgctc tttaattatc tattaacaaa tactccacaa atatttgctg atgtgcgtac
    35161 ttattggagt ccagaggctg ttaaacgtgt aacgggacat actttagagg gtcgtgctgc
    35221 agctggcttc ttacatctaa tcaactctgg ttcttgtaca ttggatggta caggtcaagc
    35281 tactcgagat ggcaaacctg ttatgaaacc attctgggag ttggaagaaa gtgaagtgca
    35341 ggctatgctt gaaaatacag acttcccacc agcaaaccgc gaatacttcc gtggaggagg
    35401 attctcaact cgtttcttga cgaaggggga tatgccagta acaatggtac gtctcaatct
    35461 tctaaaaggg gttggtccag tgctacaaat tgcagaaggt tatacacttg aacttcctga
    35521 agatgttcac catactttag ataatcgtac agatccagga tggccaacta cttggtttgc
    35581 tccacgtttg acaggaaaag gtgctttcaa gtctgtctat gacgtcatga ataattgggg
    35641 agctaatcac ggagccataa catatggaca cattggagca gacttgatta ccttggcttc
    35701 tatgttgaga attcctgtca atatgcataa tgtacccgag gaagatatct ttagacctaa
    35761 aaattggtcc ttatttggaa cagaagatct agaatcagca gactatcgtg catgtcagtt
    35821 gttgggaccg ctacataaat aaaaattgtg tatataggag gtgaacttat gtccctccta
    35881 tccttttaaa aagatttgtt aaacaattca caaataattg aaaacgaata caaaaactaa
    35941 tataatgatg ttaaatagat agcgcggagg cgcaggagga aaattatatg gctacatttt
    36001 atgttccggc agtcaacctt attggtaaag gtgttgtaaa tgaagtgggt ccttatatca
    36061 aggaacttgg ctataaaaag gcacttttgg tgacagataa gtacatcgaa ggcagtgaca
    36121 ttttacctaa ggttttaaaa ccactggata cagaaggaat cgaatatgtc atctttagcg
    36181 atgtagagcc aaaccctact tgtaaaaatg tcacagatgg ggtagctgct ttgcaagaac
    36241 atggctgtga ctttatcatc agtcttggcg ggggttctcc acaggatgca gctagttgta
    36301 tttctatcat ggctacaaat ggtggaaaac cacaggatta tgaagggctt cataagtctg
    36361 ctaaaaaagg cttgccagtt gtggctatca atacaacggc aggaacttct gcagaaatca
    36421 ctattaacta tgtgattact gatgaagaac gcaaggttaa gatggtaatg gttgacaaga
    36481 atagccttgc tcttatctct gttaatgacc cggaactcat gctttccaaa cctaaaggcc
    36541 tgactgctgc tactggtatg gatgctctga ctcacgctgt tgaagctttg gtaacacctg
    36601 gtgcttatga tgtaaccaag aaactgtcta ttggtgctat tgagcttatc aaggaatatc
    36661 ttcctcgtgc tgtagaaaat ggacatgata ttgaagcgcg tgaaggtatg gtcaatgcca
    36721 tcttccttgg tggtatgagc tttaataatg ctggtcttgg ttatgttcac tcaatggctc
    36781 accaactcgg tgcagtatat aatttgccac atggtgtttg ctgtgccatg ttgctaccag
    36841 ttatagaacg tgaaaatgct aaacgtgtac cagaagcttt ccgcaatgtt gccaaagcct
    36901 tgggacttca tgtagaaggt aaatcagatc aagaatgtgc cgattatgcg attgttgaga
    36961 ttgagaagct ttctgagaca gtaggtattc ctaagaaact gactgaactt ggtattgaag
    37021 aaaaagattt cgactttgaa tacctttcta agaatgcctt gattgatgcc tgcgcaccag
    37081 gaaatccatt tatgccaacc ttagaagaaa cgattgcctt ttataaagag ttattttagc
    37141 aagagattgg acgacaatag gacaattcac ctctaattat tgacatttca ggaaaaatcg
    37201 cagtaaaaac ggcacagcct tctttaaatg tgctataata ctagaaaaat acttgtggag
    37261 gttccattat ggcaatattt ttcatgattt ttctgattgt ttgtgtgctc ctattggtga
    37321 tagtcacact gagtacagtt tatgtggttc gtcagcagtc ggtggcgatt attgaacgct
    37381 ttgggaaata ccaaaaggtt gctaatagcg gtattcatat tcgcttgcct tttgggattg
    37441 actcgattgc agcacggatt cagttgcgct tgttgcaaag tgatattgtg gttgagacta
    37501 agaccaagga caatgtgttc gttatgatga atgtagcgac tcagtaccgt gtcaacgagc
    37561 agagcgtgac agatgcttac tataaactca tacgtccaga atctcagatt aaatcttata
    37621 tcgaagatgc tcttcgctct tctgttccaa aattaacctt ggatgaattg tttgagaaaa
    37681 aagatgagat tgcccttgaa gttcaacacc aagtagcaga agaaatgacc acttacggct
    37741 acattatcgt gaaaaccttg attaccaaag tcgaaccgga tgcagaagtt aagcaatcca
    37801 tgaatgaaat caatgcggcg caacgtaagc gggtcgcagc acaagaattg gcggaagctg
    37861 acaagattaa aattgtcact gcagctgaag cagaagcaga aaaagaccgc cttcatggtg
    37921 tggggattgc ccaacaacgt aaggcgattg tggatggatt ggcagagtct atcaccgaac
    37981 tcaaggaagc caatgttggc atgacagaag aacaaatcat gtctatcctc ttgaccaacc
    38041 agtatttgga taccttgaat acctttgcct ctaaaggaaa tcaaaccatc tttttaccaa
    38101 atactccaaa tggtgtggat gatatccgaa cacaaatctt gtcagccctt cgcgctgaga
    38161 agaaataata gactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc
    38221 gtatagatgt tactgacgaa gtcagttcta tctgcaacct caaaacagtg ttttgagctg
    38281 acttcgtcag tcttatctac tacctcaaaa cggtgttttg agcaacctgt ggctagtttc
    38341 ctagtttgct atttgatttt cattgagtac aaagagcttg gcaacaggct ctttttgtat
    38401 tgcgtttatt aagaaaaaca aaaaacatcg atatacattt aactaaaaat tattgtatgt
    38461 tatctccctt aattaggaat gataagggaa taactagaaa gatttgtgaa tacaaactat
    38521 ttctgatata caaaatatac agtaataatg aatgatggga gatgggatga aagaatttca
    38581 atttgagaga aagcagcgtt tttctttgag gaaatatgca ataggagctt gttcggtctt
    38641 gctaggaacg agtttatttt ttgctggtat gggtgctcag cctgtacagg ctacagaaac
    38701 gagttcagca ctaatttcaa gtcattattt ggatgagcag gatttatctg aaaagctgaa
    38761 atctgagttg caatggcttg aattagaaaa caagcttttg aacttatggg agcattaggt
    38821 tactatgaag gatttgttcc ttacgtttca aattaataca aaaaccaagc tgaagaagac
    38881 aaaccgctat ctgataaata tattttcgaa aaaatcttag gaaaaacata tgcagccttc
    38941 aaaaaagatc aaattaatga gcgtgtcgag aaattaggta agttaaaacc tattacaata
    39001 aattacaacg gaaaatcaga agtaattgat agtaaagaaa aattacaaga gcttatgaat
    39061 aaagccgtta aagacgaagt ggctcaaata tagtaaaatg aaataagaac aggacaaatc
    39121 gttcaggaca gtcaaatcga tttctaaaaa tgttttagaa gtagaggtgt actattctag
    39181 tttcaatata ctataaaatc aggcaatacc acggctaaaa agtttgagtt tatcgaaaca
    39241 ccagtgcaaa aactgaaaaa agcgatttat aaagctcatc tcaaagattc agatgacttt
    39301 agaccagaaa catccacaca aatctttttg aaagctgttt gaagctttgt ccttgctttc
    39361 ttagttcata gatctgaact ttatcttcat aactcaattt cataataaaa caccccaaaa
    39421 gttagattta ttctgtctaa cttttggggt gcagttcatt aatcggtcga ttttttttgg
    39481 tagaaacagt tgcctgatta agttgcaagt cgatagacgg cttcggcata aatatccata
    39541 gcacggtaca aatcttctag aacggcacat tcatttgcct gatgttctgt ctgcttcgct
    39601 cctgggaata aggcgccgaa ggctacacaa tttggcatgg tgcgagcaaa agtggcacca
    39661 ccggatgaaa tagcaggact gttatcgcca gtcttttctt ggtagatttg catcagtgtg
    39721 ctaacgagtt tactgtcttt tgcgacgtat agaggcgcta gatagtcaaa ctcttcgtag
    39781 cggagttggt agttttgtgc acatcttgta agcaactcta ctagttcttc cttgtcagct
    39841 aagacaggag tccgaatgtc aatacggatt tcagaacgtt catgattgat catgagacct
    39901 gcgacattaa aggataggtg accagaaggt tcatctgcta tatcaccaaa gatttgtctt
    39961 cctgtgccgt cttgacctgc ttgtgttgca agaaagctga gagcagggtg ttcttggaga
    40021 ggagcaagaa tggtagctag tcggatgaca gcattgatac cttgactagc atccttagca
    40081 tgctttggca ctccgagaac cgttacggtt tgttcagtgg attggtaatc ataaccagct
    40141 tctttgagat cgttacaaac ctgttcatag aggggacctt ggtagttggc cttgcctggt
    40201 acaacgttaa aggcgcctcc tacttcaagc tctagttgat ccgatccagg gccatgaagt
    40261 ttgacctgta gaagcccttt ttcagcatag gtcagaggaa aagatgagtc aggtgcaaag
    40321 cccatactgg cctgttcttc gatggtattg tagcgtgcca tgcagcgcca gagggtttcc
    40381 tcatcggtac caaagataaa gcgtacgcgc tttttgaact gaataccttg gtccagcaag
    40441 ctttttactg catagagagc tgcgagcgaa gggcctttat catcttggac accacgtccg
    40501 aatacccagc cgtctttgat agttgcttca aatggcggtg tctgccaatc tgcttcatca
    40561 cctgatggaa caacatccaa atgacagaga atggccagaa gctctgctcc ctgaccgatt
    40621 tctgcatatc cgtaataacc tttagggtca agataggtag tgaaacctat gtctcgacaa
    40681 atctctaaag ttttttctag gacatcttgg attgcttgtc caaaaggtgt tccattttct
    40741 ccttcattga gtactgaagg ataggaaatc aaggttttta atgatataag aaattcatct
    40801 ttaacttgat ttgttatatc tattttcatg gaatcacctc actcactatt ttataggaat
    40861 ggaaggaagg ttccaaggag aagaagggcg atggtcacta caataatagc gactacgagt
    40921 ttgcccatga atttccacca agtaccaatg ttgatacgtc caagtgcaag agctcccatc
    40981 acaataccag atgttggtgc aatcaagttc aagacacctg aagcagattg gtaagcagtg
    41041 ataatcaagc taggacggac atttacaaat tctccaagtg gagccatgat acccatagtt
    41101 gcgctggcaa gaccagatga agatgggatc aagaatgaca taggtagata gaagatataa
    41161 gttacaacga taaagacttg tgaagataga ccgctcaagc cttctttacc ccagttgagg
    41221 attgtatcgg taatcatacc gtcgttcatg ataacttgaa taccacgagc aatcgctacg
    41281 atcaaggcaa cactgagcaa gtcagcagca ccattcatga aggaagagat aatcttatct
    41341 tctttaagac cataaataac accaatcagg atacccataa aggcaaagag cattgcgcct
    41401 tctgggaagt accaagtacc tagtgcagaa gtagatgaac cgacaatatt accaataact
    41461 ggaagaccag tcaaccaagc attaaagtca tcaaaaatgg taacgccaag gtctgtccat
    41521 ggaatgaagc tcaataccat caagatgaat gtcaacacaa ataagaagag aactgatttt
    41581 tgtttgctgc taagtgtaga ttctacagat gaagattctt ctacgttaaa gtgtttcaaa
    41641 tcttctttgc gagtactata aaccagtgac ttagtcggat ctttttgaat cttatccgca
    41701 taacggtaaa caaaccaagt actaagagca gtcaaggtaa cccagaagat cagacgaagt
    41761 acgataccgt cccctgtacc aactcccgca gtcgctgaag caatacctgt cgcaaatgga
    41821 ttcagagtag atgccaaaca gccgatttga gaaccgagca aaataattgc aacaccagtc
    41881 aggctatcaa aaccaacggc catcataact ggcacaagga gtggatagaa ggccattgtt
    41941 tcttcaccca taccataagt tgtaccaccg agggcaaaca aaggcatcag taccaaaatt
    42001 aacatttttt cgcggccctt atacttcttc acgatagagg caatccctac gtcaagagca
    42061 ccagttttgt tgacaatgcc aaggaaacca ccaaccataa ggatgaagaa ggctacatca
    42121 atcgctgcgc tcgtttcttt aatgagcgaa ccttcctctg gatgagtacc tagcatagcc
    42181 cgaatcggtg ccatgaggac atcccaaatc ccttgtggat tttgaggctg agtctcgtaa
    42241 ataccttcta taaaggcccc cgcagggata aaccaagtta gcactgccat aatagcaatg
    42301 attatcaata atacggtgta agatgaaggc atcttaaacc cttttttagc tttttcactc
    42361 atttgttttt cctcctgatg tctaacaaag tgtaaaaaac caactacttt cttaaataaa
    42421 cattcaagaa aacgctttct atttatattt gttttaccat attaaagtct aaaactagta
    42481 tcttttgaaa tattgtacat gttttcaaga ataatttcta atttgatata aagatactag
    42541 aaatagaata catcttatta gtaaaacaac ttatcctttt tcaataattg ttccgctttc
    42601 agattcaatc aaggcgccta gattttcaag ggaagtaata actgcttttc cttctggacg
    42661 accattgaca aaagcgatag ctgcttctac ttttggaagc atgctacctg gtgcaaactg
    42721 atcttgtttg atatattctt ccagctgggc aacattcaca tgttccaatt tttcctggtt
    42781 tggcttgttg tagttaacaa atacataatc tacacctgtc aaaacgatga agaggtctgc
    42841 atcaaccaat tctgccaaac gttgggaagc gaagtcttta tcaataaccg cttcgacacc
    42901 agtcaaatgt ccattgtttt ctttgacgac gggaataccg ccaccacctg cagctacgac
    42961 gacttgacca ttatttaaaa gagtacggat ggtttcaatt tctttgatgt caacaggttt
    43021 tggtgaggca acgaccttac gccagccacg gccagcatct tccttgaaag tcgctccgct
    43081 cttttcggct tctgcttttg cttcttcttc tgaatagaaa ggaccgattg gtttactcaa
    43141 gttaacaaaa gctggatcat ttttatctac gacaacttgc gttacaacag aggcaacatt
    43201 tttttcgatg ccttcatcca agagagcatt ttgcaaagca tttttcaacc agaaaccgat
    43261 gctaccttct gtcatagcga caagtgagtc gagtgggaag gcagggttct tttcagagtc
    43321 tgatgccaaa tgttggagca agagattccc aacttgaggt ccattaccgt gagtgataat
    43381 caaatcatct ccatttttaa tcaattttac aagatgctta gctgtttcaa ctaaagcttc
    43441 ttgttgagcc tttgctgatg ggtcagaaga aagaatcgca tttcctccca aagctactac
    43501 aattttacga tttgccataa attctccttt atcacactca atagaatgcg tttagatttc
    43561 aatttaatga tttttcacat attttataag aaataataga ttaccattat ataaaagagg
    43621 accggactaa agctattagt cgcagccctc atagctgttg gtagacggtt tattatctaa
    43681 aattatactt taggaatata aaggttacca agtgtagcag ccataacagc tttgatagtg
    43741 tgcatacggt tttctgcttg atcgaagtgg cgagcgtact tgctgcggaa gacttcgtct
    43801 gttacttcca tttcttctac accaaatttt tcagcaacgt ctttaccata aacagtgtga
    43861 gtatcgtgga atgctggcaa gcagtgtagg aagatcaagt tttcattgcc tgctttttta
    43921 actaagtcca tattgacttg gtaaggttta agaagagcta cacgttctgc gaatttgtct
    43981 tcttcaccca ttgataccca aacgtctgtg taaagaacgt ctgcatcttt aactgcttca
    44041 tcagcatctt cagtgatgag aacatgtgcg ccactttctt tagcaaatcc ttctgccaat
    44101 tcaacgattt ctttttctgg gaagagttct tttggtgaga agatgtgaac attgacacca
    44161 aggatagcac ctgttacgag caagctgttg gcaacgttgt tacgtccatc accacagtat
    44221 accaatgtca agccttccaa gcgaccgaag ttttcttgaa cagtcaagta gtcagcgagc
    44281 atttgagttg ggtgccattc gtcagttaga ccgttccata ctggaacgcc tgagaattct
    44341 gccaattctt caaccatacg ttggctgaat ccgcggaatt caatcccgtc aaacatacgt
    44401 cccaatactt tagcagtatc ttcagtagat tcttttttac ccaactgaat atcatttgct
    44461 ccgaggtatt ctgggtgagc accaaggtcg atagccgcag ttgtaaaggc tgcacgagta
    44521 cgagtagatg ttttttcaaa taggagagcg atattcttgc cagcaaggta gtggtgttga
    44581 atattgcgtt ttttcaaatc tttcaagtga gctgaaagac caataaggta ttctaactct
    44641 gcacgggtaa agtctttttc tgctaagaag ctgcgtcctt ggaatactga atttgtcatt
    44701 ttattatttc ctctttctat tttttacatt ttctattgac gaataccgaa cagcgattac
    44761 acttcttcac gttcaaatgg catagacata caacgaggtc caccacggcc ccgaaccaat
    44821 tcacttccgc gaatcttaat caagcgaagc ccgtattctt ccaaaatctt attggtcacg
    44881 gtattgcggt cataaacaac taccacacca ggtgcgatgg tcaaagtgtt agaaccgtcg
    44941 ttccattgtt cacgcgcagc tgctacgata ttgccaccac cgcaacgaat caaatgaact
    45001 ttttctacac caaggttttg agcaagaagt tcagctaagt cacctttctc ttcaacgatt
    45061 ttaagttttt cgttttcgta agtaactgag taaacgtgaa ggtcgccttc gatttctggg
    45121 tgaatagtga acttgtcata gtctaccata gtgaagacag tatccaagtg catgaattta
    45181 cggttgttag caaattcaaa ggccaaaact ttcttgaagc caacattttt cttgaagatg
    45241 ttgaccaaaa gtttttcgat agaagctgcg tctgtacgtt gagagatacc tactgcaagg
    45301 acgtctttag aaagaactag ctcgtctcca ccttcgatac gcgtatcttc ttcacggttg
    45361 tagaccaaat ccacttttcc gccatagatt gggtggtatt tgaagatata cttaccgtag
    45421 agtgtttcac ggttacgagt gtctgcaaac atgtggttaa gcgatacggc gtttccaatt
    45481 gttgcaaatg ggtcgcgagt gaaatagagg tttggcatcg ggtcaattgc aaatggataa
    45541 tctgattcaa ctaagtcagt tagatcttta gattcgtcag gaatttctgg caattcaact
    45601 ttttgaatcc cagccattgt tttttcaacc aattcttggt tgtccttgat gccgtgaagc
    45661 aattcacgaa tagcaacctt ggtttgacga tcacggatgt tggcttcgtc taagtattcc
    45721 tcgataaatt gatcgcggat ttctggagag gtcaatgatt cagcagcgag ttgttctagg
    45781 tagagaacct caattccttc atcgcgaaga gcttgggcaa atgcatcatg ttctttttga
    45841 gcatcttcca agaaaggaat atcatcaaaa agaagccttt caagatagtc cggcaacaag
    45901 ttttctaact ccttgcctgg acggtgcaac ataacttttt tcagtttccc aatttctgag
    45961 aagacctgaa ttggatgtga agacatgtat tttcctcctt aaaaattttg acttggcacc
    46021 attttgggta ccgcttacat gtatgttata acgcaattcc taggtaatgt caatggctat
    46081 aatttctcgg aaaataatat aaattatgat gtttagcaca attttatgtt attatacata
    46141 acataggata gaatacatag atacaaatgc ataaacttct ataaaaagga tataaaattt
    46201 ttttaaaaaa tttttcaaaa aatatacaaa tgaccaaaaa gtgtccaatt atcatctggt
    46261 tatcacttgg atctgtataa agagaaatgt ttgtgtgaaa ggataaaaag atgcaacatt
    46321 cttttgaaga tagattttgg agaagcattt cttgttcaat tgtacaaatt atagaatctt
    46381 ttctgagtat ttaggaagag ataattatct tattgaccct ctttttattt tttgttatag
    46441 tcgacgaggt gatagtttag aataatcact tattcacaat ctgtggaaaa gtctggagag
    46501 tgaatggtct tcacacaatg acctgaaaga agcctgagaa taattatgga gagtagcatt
    46561 ctgagaggtg ttagcagaac catatgacag agctgtttga agagggaata ttgaggagca
    46621 aaatcctgag cctaccagtt ggagttggaa agagctggct gttagatcat ggtttattat
    46681 ccacaacctg tggataacct tgtgaacaag agaagttgct aaagaaggag atatataacg
    46741 atgaagaaaa tcaaaccgca tggaccgtta ccaagtcaga ctcagctagc ttatctggga
    46801 gatgaactag cagcttttat ccacttcggt cctaatactt tttatgacca agaatggggg
    46861 actggacagg aggatcctga gcgctttaac ccgagtcagt tggatgcgcg tgagtgggtt
    46921 cgtgtgctca aggaaacggg cttcaaaaag ttgattttgg tggtcaagca ccacgatggc
    46981 tttgtccttt atccgacagc tcacacagat tattcggtta aggtcagtcc ttggaggaga
    47041 ggaaagggcg acttgctcct tgaagtatcc caagctgcca cagagtttga tatggatatg
    47101 ggggtctacc tgtcaccgtg ggatgcccat agtcccctct atcatgtgga ccgagaagcg
    47161 gactacaatg cctattatct ggctcagttg aaggaaatct tatcaaatcc taactatggg
    47221 aatgctggta agttcgctga ggtttggatg gatggtgcca gaggagaggg cgcgcaaaag
    47281 gttaattatg aatttgaaaa atggtttgaa accattcgtg acctgcaggg cgattgcttg
    47341 attttttcaa cagaaggcac cagtatccgc tggattggca atgaacgagg gtatgcaggt
    47401 gatccactgt ggcaaaaggt gaatcctgat aaactaggaa cagaagcaga gctgaactat
    47461 cttcagcacg gggatccctc gggcacgatt ttttcaatcg gagaggcaga tgtttccatc
    47521 cgtccaggct ggttctacca tgaggatcag gatcctaagt ctctcgagga gttggtcgaa
    47581 atctactttc actcagtagg gcgaggaact ccactcttgc ttaatattcc gccgaatcaa
    47641 gctgggctct ttgatgcaaa ggatattgaa cgactttatg aatttgcgac ctatcgcaat
    47701 gagctctata aagaagattt ggctctggga gctgaggtat ctggtccagc tctttccgca
    47761 gactttgctt gtcgccattt gacagacggc cttgagacca gctcttgggc aaacgatgca
    47821 gacttgccca tccagttaga actcgactta ggttctccta aaacttttga tgtaattgag
    47881 ttgagagaag atttgaagtt aggccaacgt atttctgctt tccatgtgca agtagaggtg
    47941 gatggtgtct ggcaggaatt tggcaggggc ttcacagttg gtcataagcg cctcttgcga
    48001 ggttcgctag tagaggcaca aaaggtgcgc gtgatgatta ccgaggcaca atctattcct
    48061 gtattgacca agatttccct ttataaaact cctggattat caaaaaaaga agttgttcag
    48121 gaactagcat ttgcagaaaa aagcctagct gtggcaaagg gagaaaatgc ctattttaca
    48181 gttaagcgca gagaatgtag tggtccttta gaagctaaga tttcgattca accggggaca
    48241 ggtgtccatg gtgtcgccta tcaggacgag atttatgtcc ttcaattcca agcaggggaa
    48301 agcaaaaaag atttgcatct accaaccctg tatttcgcag gagataaaac cttggatttc
    48361 tatctgaacc taacggtgga tggtcagctt gtggatcaac ttcaagtcca agtttcataa
    48421 aagaagaacc tttgcgcgat gcaaaggttc ttttggttat tagtgacttg gtagccagct
    48481 gagggtgaaa gttagttgtt cagcttttaa gaggtcttgg tgttgaatag ttgatacgag
    48541 tgttttgttc agtcggcatt ctttgacaaa gttaaaatgg ttgtggtttt gtttagtatg
    48601 gatatccagc catttatctt ctttagctag gtagactcgt agatggtcaa agagagggat
    48661 tccgaggtca tagcttggtt ttcctggaca ggttggataa aatccgagag ctgaccagat
    48721 gtaccaagca gagagactac cattgtcttc atctccagga taggcttccc aacttgggtg
    48781 aaaagctttc tgacggagcg tcttgataag aagggcagtg tagtcagggt aatcgctgta
    48841 gcggaagaga taagggatgt ggaaactagg ctggttggaa atggctattt gtccaaaagg
    48901 agcagtagcc atctcgctca tttcgtgaat ttcataacca tagcctgttg tttcaaagag
    48961 gggagcatct tgacaggctt tcaaaagata gttgctaaag gtttcttttc cacccatcag
    49021 ttggattaag ccagggatgt cgtggagaac gcctaaagta gcttgaatgg cagagcattc
    49081 agcgtagtct cgcccccaac tataaggaga gaagtcaggg tgaaagtttc cttgattgtc
    49141 tcgtgctcgc atgtaacctg tctcagcgtc aaatagctgg cggtaatttt gtgaagcagc
    49201 cttgtaggtt tcagcgattt ctatgttctc tagttttttg gcacagctgg cgatacaaaa
    49261 gtcactatag gcatagtcta gagtatggct aacactttca tggtggtcgg tagagaggta
    49321 acctagttct tggtattggg ctagtccgtg gcggccattg atgccgagag ggtcggcttt
    49381 gctggctgtt tcgagcatgg cttggaagag ttctccttct aggtcggggg ccatgtcctt
    49441 acaggcgcta tctgcgataa tgccatctag cagtgtacct ggcatcatac cccgttcatc
    49501 tggagccagc cattttggaa ggaaaccagt atcgcggtag ctattgagga aaccttctaa
    49561 aaagcgttga tagtgctccg gtatgataag ggcaaagagg gggaaggtgg tgcggaaggt
    49621 atcccagaaa ccattgttgc taaagaggac accaggattg acagtaccag tagccagatc
    49681 catgtggatg gctttccctg actcatcaac ctcataaaaa gtctgtggga agaggaagag
    49741 tctgtagaga cagtggtcaa agaaggttcg gtcagcctct cctgtctcta taatgtcaag
    49801 tgggaagagg aagagtctgt agagacagtg gtcaaagaag gttcggtcag cctctcctgt
    49861 ctctataatg tcaaaacgat ggaggagatt ttcccaatcc gcttgggcac ttgttttaca
    49921 gctatcaaaa tcttcttgag gtagattgat tagagcttga gaaggagaga tgaaagaagt
    49981 ggctagttgc atctcggttt gactacttgc taagtcaatt cgccagtctc cagcttcttg
    50041 gctgatagca agaatatccg tgttcatttg cagggcagtg aacatcgtta gcgaattttt
    50101 gttagtttca gttttacctt cttgtcgcag ggcaagagtc cgcttatcta cttgctctac
    50161 tgtcagttca tctgctgcgt gaagatagag ggagagggct ttgccttgct tttgattcaa
    50221 acgaatagaa gcaccatagc aagtcggtgt gagctgggtt tcaatctgat aacgcagaga
    50281 aaagagcttc aaatagtgag gctggaagca agctttatct atatcataag aagactggcg
    50341 gtgaaagagg ctgtctcccc ccagttgact ggtgacaggt gtcagaagga gccaagagta
    50401 gtccccaatc caaggactgg gctggtgagt taatcgaatc ccctgaaaga taggcagatg
    50461 cggatcaaaa aaccaagatc catcctggtc actggtctgg ggcacaaagt aattcatacc
    50521 aaaaggcacg cctgtgtatg gcagggtatt tccccgagag aaggcatgct tgctagcagt
    50581 accaaagcgg gtatcgatgg tttcaagtag tggtttcata gtctttcctt tagctgtttt
    50641 tctacattat atcagaaaaa gagggccttt agaaaaggag tttcaaaaat aactattttg
    50701 tagaaaaatg actatcattt gtgtatgtat tttctgtctc aaaagctata tactgaacat
    50761 gaaacttgtt tgaaagaggg aattgcacga tgatttattc gaaagaaatt gttagagaat
    50821 ggctagatga agtagcagag cgggccaagg accatccaga gtgggtggat gttttcgagc
    50881 gttgctacac cgataccttg gacaatacgg ttgaaatctt agaagatggt tcaacttttg
    50941 tcttgactgg ggatattcct gctatgtggc ttcgggattc gacagcccaa ctcagaccct
    51001 acctgcatgt ggctaaaaga gattccctcc tgcgtcagac cattgcaggt ttggtcaaac
    51061 gtcagatgac cttggtactc aaggatccct atgctaactc cttcaacatt gaggagaact
    51121 ggaaagggca ccacgagact gaccacacag accttaacgg ctggatctgg gagcgcaagt
    51181 atgaggtgga ttcgctttgc tatcctttgc agttggctta tctcctctgg aaagagactg
    51241 gcgagactag tcagtttgat gagatttttg tcgcagcgac taaggaaatt ctccatctgt
    51301 ggacggtaga acaagatcat aagaactctc cttatcgttt tgtccgagat acggaccgca
    51361 aggaagacac cttggtaaat gatggctttg gacctgattt tgcagtgaca ggaatgactt
    51421 ggtcagcctt tcgtccgagc gatgactgct gtcagtatag ttacttgatt ccgtcaaata
    51481 tgtttgctgt agtagtcttg ggttatgtgc aagaaatctt cgcagcatta aacctagctg
    51541 atagccagag tgttattgct gatgccaagc gtcttcagga tgaaatccaa gaaggaatcg
    51601 aaaactacgc ttacaccacc aacagcaagg gcgaaaagat ttacgctttt gaagtggatg
    51661 gcctaggaaa tgccagcatc atggatgatc caaatgtacc aagtctacta gctgcgccct
    51721 atctgggcta ctgttcggtc gatgatgaag tgtatcaagc tactcgtcgt accattttga
    51781 gctctgaaaa tccatatttc taccaaggag aatacgctag cggtctcgga agttctcata
    51841 ccttctatcg ctatatctgg ccaatcgccc tttctatcca aggattgaca acaagagata
    51901 aggcagagaa aaaattcttg ctggatcagc tggttgcctg cgatggtggt acaggtgtca
    51961 tgcacgaaag cttccacgta gatgatccga ccctctactc tcgtgaatgg ttctcctggg
    52021 ctaacatgat gttctgtgag ttggtcttgg attatttaga tattcgctaa ggggctcgct
    52081 ttagctcaac cgattcttat cagaatcaca agtttacatt taaaacgtta aaatttaaat
    52141 ttagaatgag gttttacttc atggaaaatg ttgttgtaca tattatctca catagccact
    52201 gggaccgtga gtggtacttg ccttttgaaa gccatcgtat gcagttggtg gaattgtttg
    52261 acaatctctt tgaactcttt gaaaatgacc ctgagttcaa gagtttccac ttggatggac
    52321 aaactattgt ccttgacgac tacttacaaa ttcgccctga aaatcgcgac aaggtccaac
    52381 gctacattga cgagggcaaa cttaaaattg gtccctttta catcttgcag gatgactact
    52441 tgatctccag tgaagccaat gtccgcaata ccttgattgg tcaacaagaa gctgccaaat
    52501 ggggtaaatc aacccagatt ggctactttc cagatacctt tggaaatatg ggacaagcgc
    52561 ctcaaattct tcaaaaatca ggcattcacg tggcggcctt tggtcgtggt gtgaagccga
    52621 ttggatttga caaccaagtc cttgaagatg agcagtttac atcccagttt tcagaaatgt
    52681 actggcaggg tgtggatggt agtcgtgttt taggtattct ctttgctaac tggtacagta
    52741 atgggaatga aatcccagtt gacaaagatg aggccttgac cttctggaaa caaaaattgt
    52801 cagatgtgcg tgcctacgct tcgaccaacc aatggttgat gatgaacggc tgtgaccacc
    52861 agcctgtaca gaaaaatctg agcgaagcca ttcgtgtggc aaatgaactc ttcccagatg
    52921 taatctttgt tcatagttct tttgatgaat atgttcaagc tgtagaaggt gcgcttcctg
    52981 aacacttatc aactgttaca ggcgagttga ccagtcagga aacagatggc tggtacacac
    53041 ttgccaacac ttcttcatcc cgcatttacc taaaacaagc cttccaagaa aatagcaacc
    53101 tcctagagca agtggtagaa cccttgacta ttatcactgg tggacacaac cacaaggacc
    53161 agttgaccta tgcttggaaa acacttttgc agaatgcgcc acatgatagt atctgtggct
    53221 gtagcgtgga cgaagttcac cgcgagatgg aaacgcgttt tgccaaggtc aaccaagtag
    53281 gaaactttgt taaaagtaat ttgctcaacg agtggaaggg taaaattgct acggataagg
    53341 ctcaaagtga ctatctcttt actgtcatta acacaggctt gcatgataag gtcgatactg
    53401 tcagcacagt gattgatgtg gcgacttgtg atttcaagga attgcaccca acagaaggct
    53461 acaaaaagat ggccgctctt atcttgccaa gttaccgtgt ggaggacttg gatggtcgtc
    53521 ctgtagaggc tacaatcgaa gacctcggag ctaattttga atacgattta ccaaaagaca
    53581 agttccgcca agctcgtatt gctcgacaag tgcgcgtgac cattccagtt cagctagcgc
    53641 cgctttcttg gacaaccttc caattgctgg aaggaaaaca agaacaccgt gagggtattt
    53701 accaaaacgg agtgattgat acaccattcg taacggtgag tgtggatgac aacatcacag
    53761 tctatgacaa gacaactcac gaagcctatg aagactttat ccgctttgaa gaccgtgggg
    53821 acatcggaaa cgagtatatc tatttccaac caaaaggaac agagccaatc tttgcagagc
    53881 ttaagggcca cgaggtcttg gaaaacacag cttgctatgc taaaatcttg ctcaaacatg
    53941 aattgaccgt gcctgtcagc gcggatgaaa agctagaaga agagcaacaa ggtatcatcg
    54001 agtttatgaa gcgtgaggct ggacggtcag aagaattgac aaacattcct ctggaaactg
    54061 agttgactgt cttcgttgac aatccacaaa tccgcttcaa gactcgcttt accaacactg
    54121 ccaaggatca ccgtatccgt ctcttggtca agactcataa cacgcgtcca agtaatgatt
    54181 ctgaaagtat ctatgaggtg gtgacacgac caaacaaacc agctgcttca tgggaaaatc
    54241 ctgaaaatcc tcaacaccaa caagcttttg tcagtctgta tgacgatgaa aaaggggtga
    54301 ctgtatccaa taagggattg aatgaatacg aaatccttgg ggataacacc attgccgtga
    54361 ccattttgcg tgcatcaggt gagctaggtg actggggcta cttcccaacg ccagaagcac
    54421 aatgcttgcg ggagtttgaa gtcgagtttg cacttgaatg ccaccaagcc caagaacgct
    54481 tctcagccta tcgtcgtgcc aaagccttgc agacatcgtt taccagcctt cagcttgcta
    54541 gacaggaagg aagcgtggtt gcgattggta gcctcttgag ccattctgtt ctcagcatac
    54601 cgcaagtttg tccaacagcc tttaaagtgg cggaaaatga agaaggctat gtcctccgtt
    54661 actataatat gagtcaagaa aatgtgcgca tatcagaaca tcaacaaacc attcttgact
    54721 tacttgagcg accatatcca gttcattcag gactattggc tccacaagag attcgtacag
    54781 aattcatcaa aaaagaagaa atttaatttc aaaaagtaaa catcaaaaga aaggaggggc
    54841 gaaaaggtaa gaactaactg ctgatttgcc cctttttatg gtaaaaaaat gaccattgca
    54901 acgattgata tcggagggac tgggattaag tttgctagtc tgactcctga tgggaaaata
    54961 ctagataaga caagtatccc aacaccaaaa aacttggagg acttactagc ttggctagat
    55021 caacgtttgt cagaacagga ttatagtggg attgctatga gcgttccagg tgcggtcaat
    55081 caagagacag gtgtgattga tggcttcagt gcggtgccct acatccattg cttttcttgg
    55141 tatgaggcgc ttagctctta tcagctacct gtccatttag aaaatgatgc caactgcgtt
    55201 ggactcagtg aactactagc tcatccagag cttgaaaatg cagcctgtgt cgtgattggg
    55261 acagggattg gcggagccat gattatcaat ggtagacttc atcgaggtcg ccacggtctg
    55321 ggtggagaat ttggctacat gacaaccctt gcccctgctg gaaaacttaa taactggtcg
    55381 caactagcat caactgggaa tatggtacga tacgtaattg aaaaatctgg tcatactgat
    55441 tgggacggtc gcaagattta ccaagaggcc gcagctggta atgctctttg tcaagaagcc
    55501 attgagcgca tgaactgcaa tctggcgcaa ggcttgctca atatccagta tctgatcgat
    55561 ccagatgtca tcagtctggg tggctctatc agtcaaaatc cagattttat ccaaggtgtt
    55621 aagaaggctg ttgaagactt tgtagatgcc tacgaagaat acacggtcgc accagttatc
    55681 caggcctgca cctatcacgc agatgccaat ctctacggtg ctcttgtcaa ctggctacag
    55741 gaggaaaagc aatggtaaga tttacaggac ttagtcccaa acaaacgcaa gctattgagg
    55801 ttttaaaagg tcacatttct ctaccagatg tggaagtggc tgtcactcag tctgaccaag
    55861 cctctatctc tatccagggt gaggaaggtc actatcaatt gacctaccgc aaacctcacc
    55921 aactttatcg tgccttatcc ttgttggtaa cagttctagc agaagctgat aaagtagaga
    55981 ttgaggaaca agcagcttac gaagatttgg cttacatggt tgactgttct cgaaatgcgg
    56041 tgctgaatgt ggcttctgcc aagcagatga ttgaggtctt ggctctcatg ggctactcaa
    56101 cctttgagct ttacatggaa gacacttacc agattgaagg acagccttac tttggctatt
    56161 tccgtggagc ttattcagca gaggagttgc aggaaataga agcctatgct caacagtttg
    56221 acatgacctt tgtaccatgc atccagacct tggcccactt gtcggccttt gtcaaatggg
    56281 gtgtcaagga agtgcaggag ctccgtgatg tagaggacat tcttctcatt ggcgaagaaa
    56341 aggtttatga cctgattgat ggcatgtttg ccacgttgtc taaactgaag actcgcaagg
    56401 tcaatatcgg gatggacgaa gcccacttgg ttggtttggg acgctacctg attttgaacg
    56461 gtgttgtgga tcgtagtctc ctcatgtgcc aacacttgga gcgcgtgctg gatattgctg
    56521 acaaatatgg tttccactgc cagatgtgga gtgatatgtt cttcaaactc atgtcagcgg
    56581 atggccagta cgaccgtgat gtggaaattc cagaggaaac tcgtgtctac ctagaccgtc
    56641 tcaaagaccg tgtgactctg gtttactggg attattatca ggatagcgag gaaaaataca
    56701 accgtaattt ccgcaatcat cacaagatta gccatgacct tgcatttgca gggggagctt
    56761 ggaagtggat tggctttaca cctcacaacc attttagccg tctagtggct atcgaggcta
    56821 ataaagcctg ccgtgccaat cagattaaag aagtcatcgt aacgggttgg ggagacaatg
    56881 gtggtgaaac tgcccagttc tctatcctac caagcttgca aatctgggca gaactcagct
    56941 atcgcaatga cctagatggt ttgtctgcgc acttcaagac caatactggt ctaacggttg
    57001 aggattttat gcagattgac cttgccaacc tcttaccaga cctaccaggc aatctcagcg
    57061 gtatcaatcc caaccgctat gttttttatc aggatattct ttgtccgatt cttgatcaac
    57121 acatgacacc tgaacaggac aaaccgcact tcgctcaggc tgctgagacg cttgctaaca
    57181 ttaaagaaaa agctggaaac tatgcctatc tctttgaaac tcaggcccag ttgaatgcta
    57241 ttttaagtag caaagtagat gtgggacgac gcattcgtca ggcctaccaa gcggatgata
    57301 aagaaagttt acaacaaatc gccagacaag aattaccaga acttagaagc caaattgaag
    57361 acttccatgc cctctttagt caccaatggc tgaaagaaaa caaggtcttt ggtttggata
    57421 cagttgacat ccgtatgggc ggactcttgc aacgcatcaa acgagcagaa agccgtatcg
    57481 aggtttatct ggctggtcag cttgaccgca tcgacgagct ggaagttgaa atcctaccat
    57541 ttactgactt ctacgcagac aaggatttcg cagcaactac agccaaccag tggcatacca
    57601 ttgcgacagc gtcgacgatt tatacgactt aatactcttc gaaaatctct tcaaaccacg
    57661 tcagcttcca tctacaacct caaaacagtg ttttgagcag cctgcagcta gcttcctagt
    57721 ttgctctttg attttcattg agtataaaaa caagaacacc ttgcttggcg cagggtgttt
    57781 cgcgtgaaac agaagaatta tctggtttca aatgctacag ttagacaaac ttatgataaa
    57841 atagcagaaa gtgaatgttt cctaagagca attctatcga tgagcaattg gaggtattat
    57901 gctacactta aaattagtaa aacaagaaat agaagctgaa aagccagcat ctgtagaagc
    57961 ttggatcatt tccgtcaaat ttaaaaaagg ttgctaccga catatataga ttccaaaaac
    58021 aaaaacgtta gcggaactag cagatgtgat tttatggagt tttgattttg caaatgatca
    58081 tgctcacgca tttttcatgg ataatgttga gtggagtcat gcagattctt actttcttag
    58141 ctttgttagt gacgatgttg aagaacgtta cacagaaaat gtctatctgg atagcctaag
    58201 tgtcaaacaa aaatttaagt ttattttcga cttcggtgat gaatggcgtt ttgaatgcca
    58261 agtgctgaga gaaatcgaga cagaggacga agaagcttat ctcgtacgtt cggttggaac
    58321 gtcgccagaa caatatccag attatgatgg ttttgactat gaagaatggt aaaattgaaa
    58381 tctaaaaaac aattggaatc agtctgtgta ggcttagtat ttcaatagac ttcctgcaaa
    58441 actagaatcc tagttcatga ttgataatac cagcaatcaa attcattcgt aatccgaagc
    58501 gtttacgatg atttcgatag gttgttgaaa acattttaaa tgtttctact ttggcaaaga
    58561 tgttctcaac cttgcttctc tccttggata gcgcatggtt acaggcttta tcttcagctg
    58621 ttagcggctt gagtttgctg gatttacgtg gagtttgtgc ttgaggatat atcttcatgg
    58681 gcccttgata accactgtca gccaagattt taccagcttg tccgatattt ctgcaactca
    58741 ttttgaacaa cttcatatca tgacaatagt tcacagtgat atccaaagaa acaattctcc
    58801 cttgacttgt gacaatcgct tgagccttca tagcgtgaaa tttcttttta ccagaatgat
    58861 tcgctaattg tttttttagg gcgattgatt tttacttccg tcgcatcaat cattaccgtg
    58921 tcctcagaac tgagaggagt tcttgaaatc gtaacaccac tttgaacaag agttacttca
    58981 acccattggc tccgacggat taagttgctt tcgtgaatac caaaatcagt cgcaatttct
    59041 tcataagtgc ggtattctcg cacatattga agagtggcca taagaaggtc ttctaggctt
    59101 aatttaggtt ttcgtccacc ttttgcgtgt ttaagttgat aagctgtttt taacacagct
    59161 aacatctctt caaaagtggt gcgctgaaca ccaacaagac gcttaaatcg tgcatcggtt
    59221 agttgtttac ttgcttcata attttgtttc gcaggaagtc tattgactcc ttggtagggg
    59281 tcaatgtttt tttttcatct atcccgagaa ttattttccc gccatttgta tttgcaaatg
    59341 ctgagtaggt ttcccagaaa gactctggaa gattgttttt agcttttttg tattctaaat
    59401 caaccccttc aaattttaag tccatatttt tcctttacat ctgttttttg tggttctggt
    59461 atttgttcaa gttgagtgat aatatagcta attgaatttc gagagttttt actcagttaa
    59521 tttctttttt aacccacttt aatttctttt ttaacccggg ttaaaaaag
//
LOCUS       DAVLIK010000008        53354 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLIK010000008 DAVLIK010000000
VERSION     DAVLIK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53354
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.008"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(43..2589)
                     /locus_tag="VXE87_000499"
     CDS             complement(43..2589)
                     /locus_tag="VXE87_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0842098.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLAAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(2712..3152)
                     /locus_tag="VXE87_000500"
     CDS             complement(2712..3152)
                     /locus_tag="VXE87_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0842099.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQIHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(3127..3996)
                     /locus_tag="VXE87_000501"
     CDS             complement(3127..3996)
                     /locus_tag="VXE87_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0842100.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYCFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGINDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(3974..4474)
                     /locus_tag="VXE87_000502"
     CDS             complement(3974..4474)
                     /locus_tag="VXE87_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0842101.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKMRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(4485..5183)
                     /locus_tag="VXE87_000503"
     CDS             complement(4485..5183)
                     /locus_tag="VXE87_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0842102.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     RFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(5176..5442)
                     /locus_tag="VXE87_000504"
     CDS             complement(5176..5442)
                     /locus_tag="VXE87_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0842103.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(5508..6434)
                     /locus_tag="VXE87_000505"
     CDS             complement(5508..6434)
                     /locus_tag="VXE87_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0842104.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(6509..7324)
                     /locus_tag="VXE87_000506"
                     /pseudo
     CDS             complement(6509..7324)
                     /locus_tag="VXE87_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7328..7648)
                     /locus_tag="VXE87_000507"
     CDS             complement(7328..7648)
                     /locus_tag="VXE87_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0842105.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGD"
     gene            complement(7934..9931)
                     /gene="metG"
                     /locus_tag="VXE87_000508"
     CDS             complement(7934..9931)
                     /gene="metG"
                     /locus_tag="VXE87_000508"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0842106.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQVYVDRMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDCLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDAVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(10055..11314)
                     /locus_tag="VXE87_000509"
     CDS             complement(10055..11314)
                     /locus_tag="VXE87_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842107.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(11316..12017)
                     /locus_tag="VXE87_000510"
     CDS             complement(11316..12017)
                     /locus_tag="VXE87_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842108.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(12001..13200)
                     /locus_tag="VXE87_000511"
     CDS             complement(12001..13200)
                     /locus_tag="VXE87_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0842109.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            13486..14832
                     /gene="gor"
                     /locus_tag="VXE87_000512"
     CDS             13486..14832
                     /gene="gor"
                     /locus_tag="VXE87_000512"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0842110.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGVKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQVAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            15029..15565
                     /locus_tag="VXE87_000513"
     CDS             15029..15565
                     /locus_tag="VXE87_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0842111.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            15620..15700
                     /locus_tag="VXE87_000514"
                     /pseudo
     CDS             15620..15700
                     /locus_tag="VXE87_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(15769..15984)
                     /locus_tag="VXE87_000515"
     CDS             complement(15769..15984)
                     /locus_tag="VXE87_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0842112.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            16082..16402
                     /locus_tag="VXE87_000516"
     CDS             16082..16402
                     /locus_tag="VXE87_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842113.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(16432..16770)
                     /locus_tag="VXE87_000517"
     CDS             complement(16432..16770)
                     /locus_tag="VXE87_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842114.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(16782..17501)
                     /gene="trmD"
                     /locus_tag="VXE87_000518"
     CDS             complement(16782..17501)
                     /gene="trmD"
                     /locus_tag="VXE87_000518"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0842115.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(17491..18009)
                     /gene="rimM"
                     /locus_tag="VXE87_000519"
     CDS             complement(17491..18009)
                     /gene="rimM"
                     /locus_tag="VXE87_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0842116.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(18114..18399)
                     /locus_tag="VXE87_000520"
                     /pseudo
     CDS             complement(18114..18399)
                     /locus_tag="VXE87_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(18400..18828)
                     /locus_tag="VXE87_000521"
     CDS             complement(18400..18828)
                     /locus_tag="VXE87_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0842117.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKKLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEE"
     gene            complement(19405..19644)
                     /locus_tag="VXE87_000522"
     CDS             complement(19405..19644)
                     /locus_tag="VXE87_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0842118.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(19664..19936)
                     /gene="rpsP"
                     /locus_tag="VXE87_000523"
     CDS             complement(19664..19936)
                     /gene="rpsP"
                     /locus_tag="VXE87_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0842119.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            20115..20315
                     /locus_tag="VXE87_000524"
     CDS             20115..20315
                     /locus_tag="VXE87_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842120.1"
                     /translation="MNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDLLAD
                     DSLAGDIILLWRIQFGTFTTET"
     gene            20794..21006
                     /locus_tag="VXE87_000525"
     CDS             20794..21006
                     /locus_tag="VXE87_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842121.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            21089..21892
                     /locus_tag="VXE87_000526"
     CDS             21089..21892
                     /locus_tag="VXE87_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0842122.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITINSIEVVKDYDFKS"
     gene            complement(21949..23490)
                     /locus_tag="VXE87_000527"
     CDS             complement(21949..23490)
                     /locus_tag="VXE87_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0842123.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(23492..23974)
                     /locus_tag="VXE87_000528"
     CDS             complement(23492..23974)
                     /locus_tag="VXE87_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0842124.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(23974..25059)
                     /gene="rlmN"
                     /locus_tag="VXE87_000529"
     CDS             complement(23974..25059)
                     /gene="rlmN"
                     /locus_tag="VXE87_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV0842125.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDSVEQALE
                     LTELLKNIKKLSYANLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(25080..25610)
                     /locus_tag="VXE87_000530"
     CDS             complement(25080..25610)
                     /locus_tag="VXE87_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0842126.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(25767..26372)
                     /locus_tag="VXE87_000531"
     CDS             complement(25767..26372)
                     /locus_tag="VXE87_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0842127.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(26545..27582)
                     /locus_tag="VXE87_000532"
     CDS             complement(26545..27582)
                     /locus_tag="VXE87_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0842128.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(27616..28551)
                     /locus_tag="VXE87_000533"
     CDS             complement(27616..28551)
                     /locus_tag="VXE87_000533"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0842129.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(29104..30294)
                     /locus_tag="VXE87_000534"
     CDS             complement(29104..30294)
                     /locus_tag="VXE87_000534"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0842130.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(30509..31852)
                     /locus_tag="VXE87_000535"
     CDS             complement(30509..31852)
                     /locus_tag="VXE87_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0842131.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYWLTQLMQPYLAMIFVNTKTRADELHSYLTSQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(31992..32807)
                     /locus_tag="VXE87_000536"
     CDS             complement(31992..32807)
                     /locus_tag="VXE87_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0842132.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            complement(32859..35039)
                     /locus_tag="VXE87_000537"
     CDS             complement(32859..35039)
                     /locus_tag="VXE87_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0842133.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(35325..36251)
                     /locus_tag="VXE87_000538"
     CDS             complement(35325..36251)
                     /locus_tag="VXE87_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842134.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(36244..36936)
                     /gene="ftsE"
                     /locus_tag="VXE87_000539"
     CDS             complement(36244..36936)
                     /gene="ftsE"
                     /locus_tag="VXE87_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0842135.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(36954..38049)
                     /gene="prfB"
                     /locus_tag="VXE87_000540"
     CDS             complement(join(36954..37976,37978..38049))
                     /gene="prfB"
                     /locus_tag="VXE87_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0842136.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKMSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTYIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(38157..38813)
                     /locus_tag="VXE87_000541"
     CDS             complement(38157..38813)
                     /locus_tag="VXE87_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0842137.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIVRTSAKVL
                     "
     gene            complement(39227..39937)
                     /locus_tag="VXE87_000542"
     CDS             complement(39227..39937)
                     /locus_tag="VXE87_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842138.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGS"
     gene            complement(39937..40701)
                     /locus_tag="VXE87_000543"
     CDS             complement(39937..40701)
                     /locus_tag="VXE87_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842139.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(40701..41657)
                     /locus_tag="VXE87_000544"
     CDS             complement(40701..41657)
                     /locus_tag="VXE87_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0842140.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(41661..42530)
                     /locus_tag="VXE87_000545"
     CDS             complement(41661..42530)
                     /locus_tag="VXE87_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0842141.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(42798..43958)
                     /locus_tag="VXE87_000546"
     CDS             complement(42798..43958)
                     /locus_tag="VXE87_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0842142.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(44059..44307)
                     /locus_tag="VXE87_000547"
     CDS             complement(44059..44307)
                     /locus_tag="VXE87_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0842143.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(44386..44976)
                     /gene="clpP"
                     /locus_tag="VXE87_000548"
     CDS             complement(44386..44976)
                     /gene="clpP"
                     /locus_tag="VXE87_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0842144.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(45150..45779)
                     /gene="upp"
                     /locus_tag="VXE87_000549"
     CDS             complement(45150..45779)
                     /gene="upp"
                     /locus_tag="VXE87_000549"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0842145.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(45868..46335)
                     /locus_tag="VXE87_000550"
     CDS             complement(45868..46335)
                     /locus_tag="VXE87_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0842146.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(46354..46911)
                     /locus_tag="VXE87_000551"
     CDS             complement(46354..46911)
                     /locus_tag="VXE87_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0842147.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            47036..47881
                     /locus_tag="VXE87_000552"
     CDS             47036..47881
                     /locus_tag="VXE87_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0842148.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            47940..49115
                     /locus_tag="VXE87_000553"
     CDS             47940..49115
                     /locus_tag="VXE87_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0842149.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            49135..49590
                     /locus_tag="VXE87_000554"
     CDS             49135..49590
                     /locus_tag="VXE87_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0842150.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(49610..50359)
                     /locus_tag="VXE87_000555"
     CDS             complement(49610..50359)
                     /locus_tag="VXE87_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0842151.1"
                     /translation="MYHIKEAAQLSGISVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            50587..51922
                     /locus_tag="VXE87_000556"
                     /pseudo
     CDS             50587..51922
                     /locus_tag="VXE87_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(51962..52906)
                     /gene="manA"
                     /locus_tag="VXE87_000557"
     CDS             complement(51962..52906)
                     /gene="manA"
                     /locus_tag="VXE87_000557"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0842152.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(53027..53323)
                     /locus_tag="VXE87_000558"
     CDS             complement(53027..53323)
                     /locus_tag="VXE87_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0842153.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYKDVIDSNGVSIE"
BASE COUNT        15557 a        11712 c         9806 g        16279 t
ORIGIN      
        1 tttacatgag atagctgagt tttcttttta ttttaggctt atttatgcat ttccgtattg
       61 aagaacaact gcttcgactg cagctttttc acggctaatc aagtcaacac gcgctgcaat
      121 ttccttgatt cccataccga tgttacggct aagagcaagg tcagaaagtt gcggttcaaa
      181 gaactccttg tattccgcca agcgttgctg agtcttaaat acatgagcag gaaggataac
      241 aaagctatca aagctcatat ctcctccaag ggctgcctta atccaagccc agttttcacg
      301 cgcccaagac caagctgttt tctgagttgc ttgatgagct aggaattggt aataccaagc
      361 agacaagtcc tgtggtttga ccacaaattt gtccttccaa gaagtaatca agttttggat
      421 attatccgca tctgtactgt atgcaagagc tgctgccaac tggcgtttaa agacagcatc
      481 tgttgcgtga gtataagtat caagataaag tgctaacaag tctttagtct catgatgttt
      541 catctcatta atcagaactt gtgaacgaat agctgctggg agtcctgcaa gattctcctt
      601 gtgtgttgcg aagatttggc tagcgacttg actagcttct gcatcatttg agcgaatcat
      661 catcgaaaca gccagctgac gaaccaattc atcctcatct gattctccgt ctttagcttc
      721 aaaaccaaga cggtcatagt tatgacgagc caatttagca accagtcctt tgaaggctgt
      781 ttcagcatcc gttccttcat caataaagcg ctcaagggct gaaatcactt gagaaacagc
      841 tgaaaccacc agataagact cttccttagc aagtttatca agaactggaa gcaagtctgc
      901 ataagaaatg tgccctgcct cagccaacaa acgacgttct tgaacaattt gcagtttgct
      961 tgtgttatca agtgtctcta gctcagcaag aacagctgct aacaagtctc cttgatagtc
     1021 ggtaatatag tgggcagtat tttcagtgtt gagacgaaga gctccttcat tttcagcaag
     1081 aagagctgcg tagccaggga tttcgatact ttcagtttcg agtgtatcag gcaagccttt
     1141 ccagttgcta ttgaggggca ccacccagag acggttcttg tcttcgttct caccgatgaa
     1201 gaattgtttt tgtgaaatct tcaagacatc attttcaact ttgacagtaa gaactgggta
     1261 accaggctgt tccaaccaag aatccatgaa ggctgcgaca tcacgtcctg acgcttgacc
     1321 aagggcatcc caaagatcac taccaatggt gttgctgtat tggtgttttt caaagtaggc
     1381 atgcaaacct ttagcaaaat cagcatctcc tagccaacgg cgaagcatgt gcatgagacg
     1441 gcttcctttg gcatagacga tagcgccgtc aaagagtgta ttgatttcat ctggatgttt
     1501 aacttcgacg tggacagact gaacgccatc agtagcgtca cgttcaagag caagaggtac
     1561 tccacctgtt tggaaatctt caaagatatt ccagcttggt tcgatggtat ccacacagac
     1621 gtattccatc atattagcga aactttcatt gagccaaagg tcatcccacc atttcatagt
     1681 cacgaggttc ccaaaccatt ggtgagccaa ttcatgggcc acaacaaggg caacttgttg
     1741 acggctagca aatgtagagt tctcatcgac aaccaagtaa acttcacggt aagtcacaag
     1801 accccagttt tccatagcac cagctgagaa gtcaggaagg gcgatgtgga gagattgagg
     1861 aattgggtac ttaactccat agtaatcttc gtaaaactcg atagagcgaa cagcgatatc
     1921 cagtgagaaa tcaagatttg aaagtggatg tgctttggtt gagtagacac ctaccagggt
     1981 accattttta gttttagcgg tcaccccttg caaatcacca gcaacaaagg ccaacaagta
     2041 agaagacatg cgaggtgttg tctcaaactt ccagatacct gtttccttac ggttttcaac
     2101 atcgatttct ggcatgtttg acaaggccaa ttcaccttct gcttggtcaa agcgaagaga
     2161 gaggtcaaaa gttgctttgg cttcaggctc atccacacat gggaaagctt cgcgcgcaaa
     2221 atggctctcg aactgagtag acaagacctc cttcttgact ccatcaactg tataataaga
     2281 agggtaaatc cctgtcatgt tgtctgtaat tttaccagaa aaggcaagaa ccaattcaac
     2341 ttgaccagcc tcagccaatt cgatatgaag ggcttcattg tcatggtcaa ctgtaaatgg
     2401 acgagcttga cctgcaactt ctacagaggt gatttccaag tctttttggt ggagggagat
     2461 gcggtcactc tgtgcttgac cagtgatggt cactttccca gaaaaagtct tggtctcacg
     2521 actcaaatct aaaaataaat cataatgttc aggaacaaat tgcttaataa aatgttcaac
     2581 tgcttgcata gttttctcct attctaagtt taagagctgc tgctcttctt caaacaaact
     2641 tattatatca tattttgctt gagaaaaaag gattggacag cgatttccaa aactttcttc
     2701 cttctaatag tctacagtgg gtagaccttg cgaaattctt ctaaaacaac cttgctttca
     2761 ggtgtaaaag tcagccctac ttcacccaaa cagtctgtga aaaagtcctc atgaatctgg
     2821 cgccaatagg caagtgattt gtctccctca ccttccttaa aggcatgttg cgcagaaact
     2881 tgattgaaga gttcaacaga aacctttgta atttcgacaa tgcagacaga ctgattttga
     2941 ctatctaaaa tgacatcgaa ggtccctact tggggaagtg gttcgtcttc tagtacatag
     3001 aggtcatagg ctgatgctgt tgctgtcttt tctcctttaa acaccaaatc cgctaaaagg
     3061 tctggttcaa ctccaaaagc ccaagcatcg atttcatctc cgatcaaagg attgatttgc
     3121 ttgtatttat tccacatttc ttgcggtatc atgggtactc ctttgtaatt ttttactttc
     3181 ttcttttatg tgtttaagat gatctggatg gtcaatctct aaatcaaaaa tctctggaat
     3241 agaactgtag tggataatgc acttgatacc caactgattc attttttgta tgaaagaagt
     3301 attcagatag cctgctacag caaaattaat cttgttcttt cttgctttat cctgcatatc
     3361 tcttagcata tctaacatta ttggactttc cagatcatgc cattgactgt ttctcatagt
     3421 cgcaaaaaca aaggaagtca aatcatttat tccaactaca atctttgaaa tgcccgtttc
     3481 cagtatacta gataagtcaa aatacgctga cggtaattca atcatcgttc cgactttccc
     3541 agtaaagcca tactgacgca atactgtaat agcttgtttt aattggtcgg catcattgac
     3601 aaaaggaaag ataagagaca gattggggtt ggtttgataa acttctgtaa cgacatgtgc
     3661 ttcagcctga aattcatcca aacacgccag taaacgcctg gttcctctat agccaaacaa
     3721 gggatgccct tcgtcaaaaa actctttagt ccccactaaa caattggctt ctgtattcgt
     3781 taattcagta aaacaatacc aaacttcttc atctgagtac agggagcaga tagtctctag
     3841 ataatctttt acaaattgct gacaacttgc taatatgatg ttttgattaa gctctctcaa
     3901 caaatattcc ccacgaatca tgccgacgtg gtgaaatagt tgaggataaa ttttttcaag
     3961 aattttttcg ccactaaggg caagttgatt tctcatcatt caccttccaa ttcatgtaag
     4021 aagtcttgtc cagttctgga aatcctaata attcagactt aaccttcaag actaatggcg
     4081 atgcattttc ttctgtaatc tcttgaatat ccatccaaat atatccaagt gaatcattcg
     4141 caccatcaga cacagcttcc gaagtcgtaa cttgaggtgc actctcattc atttcaacat
     4201 catacaaggc catgacatgg tgaaccataa aatttgttaa ctcttctctg acgaaaacat
     4261 cgtagattcg aggattagag tagcttctaa cagtaaatcc cgtctcttcc ataacttctc
     4321 tagtcagcgt ttccgtcagt ccttcaccaa gttgctgact gcctccaggt agatcatacc
     4381 gatgttgata agggcctctc attttttcaa tgcagagtaa cttcccattt tctaagcaaa
     4441 cagcgtagac tccaaagtgt tttttgattt ccatccaact cctcctactt caaagaccag
     4501 ccaccatcta ttgtcaagat ttgtccttgc atggcgctcg cttttccact tgctaaaaaa
     4561 agactaagct ctgctatttc ctctggctca atccagcgct tgattggggt ttcactagcc
     4621 acccagtcag ccaaaccacc tggttcaaaa tccgcagcgg tcatagctgt cttgactgct
     4681 cctggagcga taccaaagac ctgaatccca gcttcagcat agtctagagc caactgcttg
     4741 gtgaagccag ccaaggcatg cttggatgaa gtataggcgt gaccacctcc acctgctagg
     4801 ctagaagcaa tggaacacat attgatgatg attccctttt tattttccag catttgtgtc
     4861 aaataatacc gagtcaactc tactggaata atgtagttga tttcaaaaat ctcttgaatg
     4921 tcctgcgccg tttgttccaa cagtggtttg taatcatcca aaactccagc agtattacac
     4981 aaaacatcca cctgagggca ccagtcaaaa ataggttcca agtccaaggt caaatctctc
     5041 tgtaaaaagc gaaaatcacc ctctaagagt ggcttttcac cttggtcaac tccataaact
     5101 tgatagccct tctctaaaaa gaggcgagct tgagccaatc cgatccctga actcactcct
     5161 gtaatgagta cacgtttagt catgcacttc tacccaatcc gttgccaaaa catcacaaac
     5221 tgtcgggctc cacatggaaa aaccttctcc ttcgccagaa acgttgatta ggaaataagg
     5281 tgtcatttca agtgcaagcc cattttgctc gatggtatca aagagttgga catagttttc
     5341 cgcacctccc caaccagttc gtacatattt tctcttagcc tttaacccag gcaggatctc
     5401 ttcaaatgtc atgtttttct cctttaattc tacattcttc atttaattat agcaaaaaac
     5461 cgctttatac ggctttttga atgtgagtta ttcaaacctg ctactactta cggcaaatta
     5521 ttccctgcag caagataaat ttcataccat tcttttcttg ttaagctaaa gtttgccgct
     5581 cggctaactt ctctcaagtg cttaggattt gttgtaccta cgactgcctg catttttgct
     5641 ggataacgca atatccaaga aatggcaata gttgaagagg ttactccata tttaatagct
     5701 aaacgatcaa gtacttgatt taaagcttga aatttctcat ttccaacaaa attcccttta
     5761 aaatacccga attgtaagac agaccatgct tgaatgacca catcgtgtaa ttggcaatat
     5821 tcaaaaatgc tgccatctcg catagctgct tgactatctt ccatattaac atgaaaagct
     5881 gattcaaatc ctggagtaaa agccgcactc aattgtagct gattaacagc taacggctgc
     5941 ttgacatctt ttttaagcaa ctccatcatc ataggatttt gattagaaac tccaaaatct
     6001 cgaactttac cttgtttata aaggagatta aaggcttctg ctacttggtc agattccatc
     6061 aaagcatctg gtcgatgaag gagcaagcta tctagatgat caatcttcaa tctttgcaaa
     6121 ataccgtcta ctgattttat aatatagtcc ttagaaaaat caaaataggt aaattcttca
     6181 atgcgaatgc cacatttgga ctgaatccac atcttttctc ttaaatctgg acgatttttt
     6241 aggacaagac ctaacagttc ttcacaacga ccacgaccat aaatatcagc caagtcgaag
     6301 gcattgattc caacagaaag tgctgtttct acaagctctt caacttcttt tacagattta
     6361 tcttttattc tcatcattcc gagaacaatt tctgataatt ctttgtcatc ttgaccaaga
     6421 gttatgtatc tcatcaaatt tttctccttt aatttctaac attcttccct tcattataac
     6481 aaaaaaccgc tttgcaacga ctttttgact atacttcact ccattttatc ttcttaaacc
     6541 cacggaacaa gacaaagatt ccaataaaga ggacagctaa aggaataact tttgtaagga
     6601 aaacatttga aattcccatc cactcataat aacggagcag agaacccacc acaagatggg
     6661 caataatcat actgacaaat ggacgaaaga ccgcttcttt ccaattccaa ataccgataa
     6721 ctagcgaaat cgtaaagata gacaaactat cccagggagc cggaatataa aaggctcctt
     6781 cttgtatgaa gcttgccatt cctacatatc ctaaaacaac tagaagaact atagtcccaa
     6841 caacaatgta agtgccaatt ttcattttag gagaatcttg gactaaactt cttcgtaaaa
     6901 ttgtggccac aagtccaaat ccaatcagaa aaataagaag ttaccctaaa aatgtgagca
     6961 aattgactgt taagagagga cctttagaaa aatcacttag tagttgataa taacgtaata
     7021 ccgccaggac aagaattggc gtcaaaaggg actctttgat agaactgcga ggtgctccct
     7081 tgagaatctc tttcattatt tttttaggat tcttacctag ataatcctct gcactcatgc
     7141 catctcgttc tgcttctgag aaatctagca tcatcaaata gatctgctct ctgagatagt
     7201 cttcatcata gagaaatcca gcaagattaa aactttccca caactcctca aaatactttt
     7261 gattctcctc agaaaactca tgtagcaaag cgcttgtttc ttcgtaatac ttcattttct
     7321 tcatggttta atccccattc ttaatccctt ctactttttg actcaaatcg tcccattgtt
     7381 gccaaaagac tgagacacgc tcttctcctt ctttcattaa tgaaaaatac ttccgatctg
     7441 gaccatctgg cgacgggcgc atgtcgcctc ttatccactg atttttttct aacttttgca
     7501 acaaaggata aatagttcct ggaacgatag tatcaaatcc agcctctcgc aaagtctgaa
     7561 ccaactcata accataccgc tctttttgac caatcatatc caagacacaa ccttcaagaa
     7621 caccttttaa tagctgagtt tctttcatca cttctccctt ctaatctatt ttgtaatacc
     7681 tactagtaac ttcacctata gtatattact tctacactag tttgtaaagc ataatagtta
     7741 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ctaccgtatg tatggttact
     7801 gacttcgtca gttctatcta caacctcaaa gcagtgcttt gatcaacccg cggctagctt
     7861 cctagtttgc tctttgattt tcattgagta taaataaaaa aacagaacta gtctgaacta
     7921 gtcctgtcta cttttaccca atcacacttc catttggtac agctggatca actgtgagaa
     7981 gggttaattt gccatcatgt tcagctgaga gaatcatacc ctggctgaca tattttttca
     8041 tcattttacg tggtttgagg ttagcaacga tttgaacttt cttgccgacc aattcttgtt
     8101 catttggata gtattttgca attcctgaaa gaatctgacg atcttctcca tcaccagcat
     8161 ccaagcggaa ttgaagcaac ttatctgaac cttctacttt agacacttct ttgacttctg
     8221 cgacacggat ttcaaccttg tcaaagtctt caaacttgat ttcatccttg tttagtttga
     8281 gctcaactgc gtccggattc cattcttttt cgactgctgg tttattgcct tccatttgtt
     8341 ccttgatata ggcgatttct tcttccatat ttagacgtgg aaagataggt gttcctttgg
     8401 caactacagt cacatctgct gggaagtcag ccaaactcaa gttttcaaga ctagaaactt
     8461 cttccaaacc aagttgagtc aaaactgcac gactagtttc catcataaat ggttcaatca
     8521 agtgagcaac tacacgaatg ctggctgcca agtggctcat gacacttgcc aattggtcac
     8581 gaagagcttc atccttggcc aagacccatg gtgcggtctc atcgatgtat ttattggtac
     8641 gagagatcag agtccagact gcttcaagcg cacgtggata gtcaactgct tccatgtgtg
     8701 tatggaagtc tgcgattgat tgttctgcaa cctcagcaag aacatgatca aattcagtca
     8761 caccttctac ataggcaggg atttgtccat caaagtactt attaatcatg gaaaccgtac
     8821 ggttaaggag gttcccaagg tcattagcca attcatagtt gatacggccg acatagtctt
     8881 caggagtaaa ggttccgtct gaaccaactg gaaggttacg catgaggtag taacgaagtg
     8941 gatctagtcc ataacgctct accaacattt cagggtaaac gacattccct tttgacttag
     9001 acatttttcc gtctttcatg acaaaccaac catgggcaat caaacgatca ggtaatttaa
     9061 catccaacat cataagaagg attggccagt agatagagtg gaagcgaagg atgtcttttc
     9121 ctaccatatg gaagactgtt ccattccaga acttgtcaaa gttaccatgt tcgtcttgag
     9181 cgtagccaag agctgtcgca tagttaagaa gggcatcaat ccaaacgtag acaacgtgtt
     9241 ttggatttga tgggacaggc actccccatg taaaggttgt acgagatacc gccaagtctt
     9301 ccaagcctgg ctcgatgaag ttgcgtagca tttcattaag gcgaccatct ggcgtgataa
     9361 attcaggatg agctttgaaa aattcgacca aacagtcttg gtatttgcta aggcgaagga
     9421 agtatgattc ttcagaaacc cattcaacct catgacctga tggagcaata ccaccagtca
     9481 catttccagc ttcatcacgg aaaacttctg ccagctggct ttctgtaaag aattcttcgt
     9541 ctgatactga ataccaacca gagtattcac ccaagtagat atcatcttga gcaagtaagc
     9601 gttcaaagac ctgtgcgaca actttttcat ggtagtcatc agttgtacgg ataaatttat
     9661 cgtatgagat atctagtaat tgccagagtt ctttaactcc aaccgccatt ctatcaacat
     9721 agacttgagg tgtaatacca gcttcttccg ctttctgctg gattttctga ccatgttcat
     9781 caagacctgt cagataaaat acatcgtagc ccatcaggcg tttgtaacgt gctaggacat
     9841 cacatgcgat agttgtgtag gcagaaccga tatgaagttt cccagatgga tagtaaatcg
     9901 gcgttgtaat ataaaaattc ttttcagaca taatttttcc tttccaggca aatgaaacct
     9961 gtttttctaa cacttcatta tatcacattt ttaatgaatt tcgataggga aatccataca
    10021 aaaacaagat agacgagtgt ccatcttgtt gatcttattc ataacgaagg gcttcaattg
    10081 gatcaagttt cgatgccttg ttggctggca agactccaaa aatcatacca acactagccg
    10141 aaactgcaag actaaatagg gcaactggga ttgatactcc aacttctata ccttctatta
    10201 aaccttgcag taacaaacct gctaaggcag ttaaaccact tgcaattgtc aagccaatta
    10261 agccacctaa caaggtcaaa atcatggatt caatcaaaaa ctgaattaaa atattggcac
    10321 gtgttgcacc caaagcctta cgaagaccaa tctcacgagt gcgctctgtc accgaaacca
    10381 gcatgatgtt catgacacca gttcctccaa caaagagaga aatccctgcg atggaactaa
    10441 taatcgtcgt cataaaacta aacgattgtt gaatttctgc aaatacaacg gactcatctg
    10501 ccacctggta ttctccctgt tgtaagcctg caagctctgt catttttcgt gccagttctg
    10561 gacccagagt tggggttaaa ctggtatcat tcactcgaaa gacaatacta gctatttcat
    10621 ctatattaaa attcgcagca agggagatat tggtagtaat aggcaagcca ccaaacccat
    10681 atatttttga ccttttagcc tccggactag tataaacccc aatgacccgg taactaaatc
    10741 cattgacttc tacaaccttg ttaatagcct cttgaggaga ttcaaataaa ctaatggaca
    10801 attcctcatc tagcaaaata acacttgcaa actctttgaa atcttgctct ctcagactac
    10861 gacctgcaat aatttcattc ttaacagcat ccatgtaagt tctgtttcca cctgtcaaat
    10921 tagcattctc aaccttttta tcttgatagg tcaagatggc attcgttgaa ttggttacat
    10981 agtaactatc cactcccttc agtttagctg cctcttgaac ccaggattct tgcggttttg
    11041 gcggttcaac aggaacttcc tcttcctttc cagaaaccgt aaaagctgat tgtttctgag
    11101 taaaagaccc atctttactt tttttaggag agaaaaagac gctaatattt ttctgagatt
    11161 tagtcatatc tttattgact tgacgagata gggaatcacc caaagccata atcacaacaa
    11221 ctgatgaaac accgataata atcccaatca tagtaagcaa agaacgcatc ttgtgagcca
    11281 tgatagatga aaaggcaaat ttcagattct gcatcttagt tttcctcctt tcctaactga
    11341 gcactgtcag acgaaatgac cccatcccga atgacaatct gacgtttggc ataggcagca
    11401 atctcaggct catgcgttac catgataatg gtttttcctt ctttattcaa atcaaccaat
    11461 aattgcataa tttggttacc tgttttggta tccaaggctc ctgtcggttc atccgctagg
    11521 ataatagaag gattgtttac caaggcacgc gcaatggcta cacgttgctt ttgaccacca
    11581 gataattctg aaggtaaatg gtgactacgt tctgtcaatt caaccttgtc taaatattcc
    11641 tcagccaact tgcgacgttt tgaagacgaa actcctgcgt aaatcaaggg caattctaca
    11701 ttttgcagag cattgagctt cgatagaaga aagaactgct gaaagacaaa accgatttgt
    11761 tggttacgga ccttagccag ttgtttttca ccaagcccag ccacttcttg accttcaaga
    11821 taatattctc cactggttgg tgtatccaac atgccaatcg tattcatcag agtggactta
    11881 ccagacccag atggtcccat gatggctaca aattcaccct cattcacttc tagattgata
    11941 tttttgagaa cctgcagttc ttggtcacca ttacggtagc ttctgaagat attttttaga
    12001 ctaattagtt gcttcatcag ccttcacctc ttttccttct tccaaggaag atgttggatt
    12061 actgatgacc ttagcaccat ttgtcaaacc agaagtgatt tcttgatttt ctgcgtcagc
    12121 atttcccaat gaaacctcaa cttttttagc cttttgttgt tcatccacaa tccagacata
    12181 atttttacta tcatccatta ctagactgct aacaggaaca agaatagcct tagttttgct
    12241 tttaacctca atgttgacag aaaaaccttg tttcaaatca ccaacctcgc ctgtcacatc
    12301 aatagtataa gggtatttag aacctgtatt attcccggct gctggactag ctgcttcacc
    12361 attgttttta ggatagtcag aaatatagct taatttccca gtccattttt tatcaggata
    12421 cactttagaa gtaaagctta cttcttgacc tacagaaagg ttggctagat tgtactcaga
    12481 caattctccc ttgacttgta aattttcatt gctgacaata tgaaccataa cttgactcgc
    12541 ccctgttgga gatttagaaa cattgctatt gacttcgacc acagttccct ctagggtact
    12601 gagaacagtt gttgcatcca attgactttg agccttgctt aattgcgctg cagcatctgc
    12661 acgcgcatca cgggcatcac ccaattgagc atcaatagaa gcaacagaat ttccagccac
    12721 tggagttggg ctttgcaccg ttgcatcttc tcctcctact ggcgctggta actgtggagc
    12781 ctgagctgaa gcggcttcat ttcgtgcttg attgagttca ttgatatgac gatctgcctt
    12841 agctactgct cgactagctg aatcataggc cgcctgcgct tctgaactac tgtacttgac
    12901 taaagcctgc ccttcgctga ccttatcgcc cacagaaaca aggatttcat ctaaatcacc
    12961 cttactagca tcaaaataaa catattgttc attttttgct gttactgtcc ctgacaataa
    13021 aacagaggat gccacgcttc cttccttggc aacaacaaga tgagtaggct catcttttac
    13081 agcagtctga gaaggttgtc taaagagtaa aatccccccg gcacccaata caactacact
    13141 cgcagcaccg attgctgcat acagttgcca ctttttagct ttaccattct ttttcttcat
    13201 aatgaaactc cttttctttt ttacaatact ttgctattat accaaatttc cctccagcaa
    13261 acaatgcagt tcagatggaa ataatggcag ttcaggatta aacaatcgtt cggaattttg
    13321 cttttctatt gtactagata tataatacac tattttgact tatttggcaa gcttttttgc
    13381 aattttttgt gcgtagcaga tttttgcaat caaatcaaaa aaagaataaa atataactat
    13441 caaaaaagac gctctactat ttaaaagatt acaaaggagt tttcaatgag agaatatgat
    13501 atcattgcta tcggtggagg tagcggagga atcgctacca tgaaccgtgc tggtgaacat
    13561 ggagtcaaag cagccgttat tgaggaaaag aaattaggtg gaacctgtgt caacgtcggt
    13621 tgtgttccta aaaaaatcat gtggtacggg gcgcaagtcg ctgagacttt ccatcaattt
    13681 ggagaagact acggctttaa gactactgat cttaactttg actttgcaac cctacgtcgc
    13741 aatcgtgaag cctacattga tcgcgctcgt tcttcttatg atggtagttt taaacgcaac
    13801 ggtgtagact tgattgaagg tcatgctgaa tttgtagatt ctcatactgt aagcgtaaat
    13861 ggtgaactga ttcgtgctaa acatatcgtg attgctacag gtgcccatcc aagtattcct
    13921 aatattcctg gtgctgagct aggtggctct tctgatgatg tatttgcctg ggaagaactt
    13981 ccagagtcag ttgccattct aggcgctggt tatatcgccg ttgaattagc tggcgtactc
    14041 cacacttttg gtgtcaagac agatctcttt gttcgccgcg atcgtccttt acgtggtttt
    14101 gattcctaca tcgttgaagg tttggtcaag gaaatggaaa gaacaaactt accacttcac
    14161 actcacaaag tccctgtcaa gttagaaaaa actactgacg gcattaccat tcatttcgaa
    14221 gatggtacta gtcacacagc tagccaagtt atctgggcta caggtcgccg tccaaacgtt
    14281 aagggcttgc aacttgaaaa agctggagtg actctgaacg aacgtggctt tatacaagtg
    14341 gatgaatacc aaaataccgt cgttgaggga atctatgctc taggtgatgt aacaggcgag
    14401 aaagaactga ctccagttgc aatcaaggct gggcgtaccc tatcagaacg tctctttaac
    14461 ggaaaaacaa ctgcaaaaat ggactactca actattccaa ctgttgtctt ttcacaccct
    14521 gctatcggaa ctgttggttt gacagaagaa caagctatta aagaatacgg tcaagaccaa
    14581 atcaaggttt acaaatcaag ctttacttct atgtactctg cttgcacttg caaccgtcaa
    14641 gaaactcgtt tcaaattgat cacagctggt tcagaagaaa aagttgtcgg acttcacgga
    14701 attggctacg gcgttgatga aatgattcaa ggatttgctg ttgctatcaa aatgggagca
    14761 accaaggctg actttgacgc aactgtagcg attcacccaa cttcatctga agaatttgta
    14821 accatgcgtt aatcgaaaca aaagaagctg atataaatat gtctgcttct tttttaatga
    14881 ttttcgaatc aacaaaaaaa ttatccaact tgactagtca cgaaaatcgg ctgttacagt
    14941 ttttgttacc ttgtttttaa aaaatggttg acatcgactc ctatatgagt ataatagtta
    15001 atatacatta gaaaagaggt taactatttt gaaaaaagct cacgtttatg ctatccctgc
    15061 tattggggct gctctcattg ctgttttggc acaaatcagt cttccaattg gacctgttcc
    15121 cttcactctg caaaactttg caatcggctt gattgctact gtctttagac cgagagaggc
    15181 tgtactttct gctggactct atcttcttct aggtgctatc ggtcttcctg tctttgcagg
    15241 aggtggagct ggttttcagg ctttagttgg ccctactgca ggctatcttt ggttttatct
    15301 cgtttactct ggacttactt cctctctaac caacagcaag agtggtgttg ttaagatttt
    15361 tcttgcaaac ctcttgggtg atgcccttgt ctttgtcggc gggattctca gcttgcattt
    15421 cctagctgga atggcatttg aaaaagctct tgttgtgggg gttcttccct ttatcattcc
    15481 agaccttggc aaacttctgg ctattagttt tattagccgt cccctacttc aacgccttaa
    15541 aaatcaggct tactttacta actaaaaaag gataccgagt tatcatgact caatatcctt
    15601 tttttatttt gaaaacttat actcaatgaa aatcaaagag caaactagga agctagccgc
    15661 aggctgctca aaacactgtt ttgaggttgt ggatgaaact gacgaagtca gtaaccatac
    15721 atacggcaag gcaaagctga tgcggtttga agagattttc gaagagtatt agttgccttt
    15781 aaaggcatcc accatcgttt gaaattcttc atttgagaga gtaatccctt tgcccatttt
    15841 agtatggtct ggactccaag cacgaatatc aaactttgca ggggcaccat taaagctcac
    15901 acggttaatt tccttggtcc aacctttttc gttttcagaa agagtcaaca agtgctcttc
    15961 gatttcaaat gtaaattctg ccattttctt ctcctttttt agtttcatta gtttattcgt
    16021 aaaatcttgt agattttagg aaaattttat ataatattga tataaaagaa gggaggccaa
    16081 tatgagacat aaattccagc aagttctaaa taaaatacat gattttttaa atggatatga
    16141 ccaacctgac cagactgaaa ccaactccct tacagccact attgaagagg ctatccagaa
    16201 acaaaccgct gttcacctta tcttatctga gacaagcttt acaggtgaca tcatcaaata
    16261 tgatcagcaa ggccagcaaa ttatcgtgaa aaatttttcc aaaaatgtga gccggattat
    16321 ccgtataagc gatattcaac gcctgcgatt tgtcccctca actgtccaaa cagcccaaaa
    16381 aaatagattt aagaaagagt gagatgtagt tgcttcatcc cactcttttt cttagcgaat
    16441 ttgttcaaaa tgtaaatgaa ctgcgatatg atctccataa ccacttcttt ccaagtcacg
    16501 ttgtaaacga taggaaatat agtgttctgc aatggtaatg taacctgcgc ccaataaacg
    16561 atgttcaacc atagattgaa tcatactgat agtcgcacgt tccaccttgg cttcttgtaa
    16621 atccaaaact accttcttag tgacttgagc aagattttga cgcaaatcat ctgtcaaaac
    16681 ataaacagtt tgggctgcct tcaagatggc ttggtaaatc ttatctggat taaattcagc
    16741 aatttcgcca ttacgtttga ttacttgcat aggtttctcc tttattcttt gttttctttg
    16801 atttctgcca gcattttttc ttcttctact gtcagttgat aatgttcaag taaatctggt
    16861 ctgcgctcgt aggttttctt taaactctcg tacaatcgcc actgacgaat cttttcatgg
    16921 tggccactca tcaatacatc tggcacgacc atgcctcgat aatcataggg acgtgtgtac
    16981 tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga ctccttgcca
    17041 atcacttctg gaatcaggcg aactgtagca tcaatcatgg tcatagctgc caattctcca
    17101 ccagtgagga catagtcgcc tagggaaatc tcatctgtta ccaaggtctt aatgcgctca
    17161 tcataaccct catagtgccc acagataaag attagctctt cctcttgagc caaatcttca
    17221 gcataagcct gatcaaactg ctttccagca ggatcgagga gaataacgcg cggatttttc
    17281 ttttcaatag catcaaagga atcgaaaata ggttgtactc tgagcaacat gccctgaccg
    17341 cctccgtagg gctcatcatc tacatgacgg gccttttcag cattttctcg aaaattatga
    17401 tactggatat ccaagagccc tttttctcga gcctttccaa cgattgagtg ctccagtgga
    17461 gaaaacatct ctggaaagag ggttaaaata tcaatcttca tcgtctaacc cttctaagat
    17521 ttccacatcg acccgtttat ttggaatatc aacattgaga accactggtg ggatataagg
    17581 taaaagcaaa tcacgtttgc cttttcgttt gaccacccag acatcattag cacctggttg
    17641 caggatttcc ttgatggttc caaccaagct atcaccctca tagacttcca aaccgataat
    17701 ctcgtgatag taaaattcac catcgtctag gtcattcaaa tcttcctcag cgaccttgag
    17761 actgtatccc ttgtactttt cgatagtatt gatatggtac atatctttga atttaataat
    17821 gtcaaagttc ttctgtttac ggtggctagc gatggtcact gtttggacaa actgatcttt
    17881 ttcatcaaac aaagccagct cagctccttt tttaaaccgt tcttctgcaa aatccgtcac
    17941 agacaagact cgcatctcac cctgtaatcc ctgcgtatta acgattttcc caacattaaa
    18001 gtagttcatc ttgtctcctg taatctcctt ttttccatct tattctgaca attctcgaat
    18061 aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc ttcctaaaat
    18121 gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc tataagtctg
    18181 acaaaaaata aatacaggga catgagattc tatcgacaaa ttctcaaaat cttcctcagt
    18241 aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc ctttttcttg
    18301 cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag ttaagttctt
    18361 aaaataaagt tcaggaccac actcgtcaat cagcctcatc tactcttcca tttctggata
    18421 aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa ttgctactaa
    18481 agtctgacgc ttaattggtt tctcgagtaa tttgcaagct aaaattccac tccaactatg
    18541 tgcacaaagt atatattcag aaattcctaa ttcttcaagt acttcataaa ccgcatctgc
    18601 aagattatct agtttttttc cagcttggtc atgaatcgga ctcctacctg tgttcggaaa
    18661 atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg aaaaattttc
    18721 ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt gcttttgata
    18781 agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa agaaatccac
    18841 tgattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg ttccaaggat
    18901 tttctcaagt tggaggaagg ggacaacatc tctactttcc cttcaagaat ccttccaaat
    18961 tatgtttatg ttggtaatta acggctgcgg ttttgtcttt ctcaaagaca gtcttggtaa
    19021 ggtcaatatg attaatagct acgattgcga cggtgtagta aatgatatca gccagttctc
    19081 tggcaagttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct attcaaaacc
    19141 tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc agtccgagac
    19201 tgctgttaat gttcgattaa gtagtcttgg aattgcctaa acgttcaatc ttttatagta
    19261 tattgaaact agaatagtac acctttactt ctaaaacatt gttagaaatc gatttgactg
    19321 tcctgatcga tttgtcctgt tcttgtttca ttttactata tcttctattc cacacaaaaa
    19381 agcgagacat ccgtcccgcc cttcttattt ttcgtcaata acgattctta cttttttgta
    19441 ttcagttggg acagagtaga caatcgttct tatcgcagaa atagtgcgac ccttacgacc
    19501 gattacacga cccacatcgc tttgatcaag attcaaatga tattccaaaa attctggtgt
    19561 atcctcaatc ttgatagtta aggcatctgg ttgtgaaatt aagggtttca caatcgcaat
    19621 aatgagattt tcaatcgtat ccatctgtca acctacttta aacttatttt gaaaatttag
    19681 aatcgtggaa ttttttcaat acgccttctt ttgaaaggat gttacgtact gtgtctgaag
    19741 gttgagctcc attagccaac catgcaagaa cgcggtcttc tttcaaagtt acttggtttt
    19801 cagcaacaag tgggttgtaa gttccaactg tttcgatgaa acgtccgtca cgtggtgaac
    19861 gtgaatctgc tacgttgata cggtagaaag gttttttctt agaacccata cgagtcaaac
    19921 ggattttaac tgccattttt aaagtctcat ttctttaatt ttttatttcg gtgaaatagc
    19981 tgagctattt agcacatgtt ctattatagc agatttctgg caggtgtcaa gaaaaaaact
    20041 tgacagacta taaatttctt aaagtattta gaaatttgtt agaataggaa ataaatgttt
    20101 gaaagctgct atccgtgaat actattttag aaaaatttta taaagaacac caagtcaaac
    20161 ccttcatatc gcctgaacga gatttggata cttggctcct aagtcccaag cccgttccca
    20221 agcgaaatat ggacttatta gcagatgatt cactagcagg agatatcatt ttactatgga
    20281 gaatccagtt tggtactttt accactgaaa catgatttta aaaactccca ttcgaatatg
    20341 attcaaaatt cgcttagaat caatgttttc ccactttttc aaaaaataaa ttttcatcta
    20401 atttaaataa ctttcaatta agtgtgaatt ttgcttaaaa tcattaaaaa acaccccatg
    20461 gtgtgaacca tgaagtgttg caaatgctgt gttgtagcta gatcttaacg tttagagaac
    20521 tggctagctt tacgagcttt cttaagatct ggtttccaaa atactttgag tacacttatg
    20581 gtattgatgc ccctaaacat ctaaaaactc tggtagaaaa agggtatgct cttgtcgaaa
    20641 cttcttttga ctcacttgac catctaaata ctaccctgaa aaagaatatc ctgaagaaga
    20701 agggagttac tggactttct aaaatgaaat cttgcgacct ggatcaagcc cttcatgagc
    20761 atttttcaga agaagaatta gctggtcact ttcatgtcct tctatggact tttttacaat
    20821 ggcattgcta tcacacccaa tacctatcta agcgcctggt tcgtaaactt tattgcagct
    20881 cttcctctaa atttcctaat tgttgaacca attgcccgtt ttatactaag ttcttttcag
    20941 aaaccattta ctggggaaga agttgaagat tttcaagatg atgacgaaat cccaactatt
    21001 atctaatcca gttctgtaaa ctactaatat ttgaaatcca cttcctttta gggtacaatg
    21061 gtataaatga atttttgaga ggatcagaat gaaaaaacta gcaacccttc ttttactgtc
    21121 tactgtagcc ctagctgggt gtagcagcgt ccaacgcagt ctgcgtggtg atgattatgt
    21181 tgattccagt cttgctgctg aagaaagttc caaagtagct gcccaatctg ccaaggagtt
    21241 aaacgatgct ttaacaaacg aaaacgccaa tttcccacaa ctatctaagg aagttgctga
    21301 agatgaagcc gaagtgattc tccacacaag ccaaggtgat attcgcatta aactcttccc
    21361 taaactcgct cctctagcgg ttgaaaattt cctcactcac gccaaagaag gctactataa
    21421 cggtattacc ttccaccgtg tcatcgatgg ctttatggtc caaactggag atccaaaagg
    21481 ggacggtaca ggtggtcagt ccatctggca tgacaaggat aagactaaag acaaaggaac
    21541 tggtttcaag aacgagatta ctccttattt gtataacatc cgtggtgctc ttgctatggc
    21601 taatactggt caaccaaaca ccaatggcag ccagttcttc atcaaccaaa actctacaga
    21661 tacctcttct aaactcccta caagcaagta tccacagaaa attatcgaag cctacaaaga
    21721 aggtggaaac cctagtctag atggcaaaca cccagtcttt ggtcaagtga ttgacggtat
    21781 ggatgttgtg gataagattg ctaaagccga aaaagatgaa aaagacaagc caactactgc
    21841 tatcacaatc aacagcatcg aagtggtgaa agactacgat tttaaatctt aaaaaccaaa
    21901 aaaaatacag tatccacatt cggtactgta tttcttttac tctcattctt aagttaaatt
    21961 attaaaatcc catatttggt ctatccaacc ttcataaaag tctggctcat ggcagaccat
    22021 aaggatagat cccctgtatt ctttgagagc gcgtttgagc tcatcctttg catccacatc
    22081 caaatggttg gtcggctcgt ccagcactaa aacgttgttt tcacgattca tcaagagaca
    22141 gaaacgaacc ttggcttgct ctccccctga taatacttga atctggcttt caatatgttt
    22201 ggttgtcaaa ccacaacggg caagggctgc acggacttct gcttgattaa gggcaggaaa
    22261 ggcattccag acagcttcaa gaggagtttg gcgattacca ccttctactt cctgctcaaa
    22321 ataaccaagt tctaaataat ctccacgctc cacttcccca gcgattggcg agataatgcc
    22381 caagagactc ttcaagagag ttgtttttcc aataccatta gcaccaataa tcgcaacctt
    22441 ttgattgcgt tcgaaggtaa gatttaaagg cttagtaaga ggacggtcgt aaccaatttg
    22501 caagttcttg gcttggaaga taaagcgccc tggtgtacga gctggtttga aatcaaaaga
    22561 tggttttggt ttctcacttt ggagttcgat aatatccatc ttatccaatt tcttttgacg
    22621 agacatagcc atattacgag ttgcaacacg ggctttatta cgagccacaa agtccttgag
    22681 gtctgcaatc tctttctgct ggcgttcgta ggctgcctct agctgagatt tcttcatagc
    22741 ataaacttct tggaactggt agtagtcacc agagtaacgc gtcagctgtt gattttccac
    22801 atgatagaca atattgataa cgtcattgag gaatggaata tcgtgcgaaa tgagaacaaa
    22861 ggcattctca tagttttgga gatagcgctt gagccaatca atatgctcag catccaagta
    22921 gttggtcggc tcgtccaaca gcaaaatatc aggcttttca aggagaagtt ttgccaaaag
    22981 caccttggtt ctttgcccac ctgacaaaga agttacatcc gtatccatgc caaagtccat
    23041 aacaccaaga gcacgcgcta cttcgtcaat cttagcatcc aaggtataga aatcacgact
    23101 ctccagacgg tcttgaagtt ctcctacttc ttccatgaga gcatcaacat ccgcgccgtc
    23161 ttcagccatt ttcatataga ggtcattgat acgagcttca gctttgaaaa gctcatcaaa
    23221 agccgtacgg agaacatcac gcaccgactg tctttcagca aggacagagt gctgatccaa
    23281 gtaaccagcc gtcacatatt tggaccactc aacctttcct tcatctggca gcattttacc
    23341 agtcacgata ctcataaagg ttgattttcc ttcaccattg gcaccgacca ggccgatatg
    23401 ttctcccttg aggagacgga aggacacatc ttcaaaaatt gcacggtcac caaaaccgtg
    23461 actcagattt ttaacttcta aaatactcat tttaattcct tatcttgttt ttatgtaatc
    23521 gtttataaag gagccaagcc agatagccac ccaaagtgtt ggtccacaaa tcatcaatct
    23581 caaagacacg attgaaatca aagaaaaagt ccaagattaa ttgcgtacac tcgattccaa
    23641 gactcacaag aaaactaaaa agaaggacct tttttgtttt ccgcaaattt ggaaatagat
    23701 aaaggagttg gaaaatcaga ggaaaaaaca agaagacatt gaggatattt tgtaaaaaaa
    23761 tccaacataa ttgtccaatg tcactcactt cgcccagttt ccagagagaa ttgaaaggag
    23821 tcaaaagaaa aaccaggcgt ccaagatgct gaatatctgg agttcccact cccacggtag
    23881 attgttcttg aggagtaaag caaaaacaga caatgcaaat gctatagaaa atgactcccc
    23941 agaccaaaat atgattataa gtcttcttca tcattaagga tttaccgctg cgactgcctt
    24001 ctggcggtca cgtttcattg tgttagagcg caattgtcca caagctgcgt caatatctgt
    24061 accatgctct tgacgaacca cacagttgac cccttttttc ttaagcgtat catagaaagc
    24121 caacacgcgc tctttgggac tacggctata ttggtcatgc tcactaactg ggttataagg
    24181 aatcaagttt gcataagaca atttcttgat gttcttgagc aattcagtca attccaaggc
    24241 ttgttctaca ctgtcgttga cttcattaag catgatatat tcaaaggtta cacgacggtt
    24301 tgttgtctca atgtagtatt caatagcagc aaagagtttt tcaatcggaa aggcacggtt
    24361 aatcttcatg atacttgaac gaagttcatt gttgggtgcg tgaagagaca cggcaagatt
    24421 gacctgaacc ccttcatcag caaagtcacg aattttatga gccaaacctg aggttgaaac
    24481 cgtgatgtga cgagcaccga tagccattcc tttatcatca ttgatagtac gaaagaaatt
    24541 caagacattg ttgtaattat caaagggctc accgattccc atgacaacga tatggctgac
    24601 gcgttcatcc tgaccacgct catcaaagta tttctgaacc agcatgattt gcgctacgat
    24661 ttcaccgtta ttgaggtcac gttgcttctt aatcaaacca gaggcacaga aggtacaacc
    24721 gatattacag ccgacctgag tggtcacaca gacagataaa ccatagtgtt gacgcatgag
    24781 tacagtctca attaacatac cgtcgggcaa ttcaaagaga tatttgactg taccatcagc
    24841 agactcttgc acaatacctt gtttcaaggg attgaccaca aactggtcat tgagcttagc
    24901 aatcaaatcc ttggaaaggt tggtcatttc ttcaaatgac tgcacacgtt tacggtagag
    24961 ccattcccag atttgatctg cacggaattt cttttctccc tgctccaata cccattcctg
    25021 catggtttga tgtgccaaac tatgaattga gggtttcatt tcttctcctt attctctact
    25081 cacttctgac gaatgacaaa atgacgttgt cccttgtcct ctttctgaga atgctggtct
    25141 ttctgacgac gtctattctt cttatctgca ttcgactttc gtttagtttg agtcggtttc
    25201 tttccttttc tagaaggtgt ttcttcttcc gtcttacgca ttttcttgtc aaatgatgct
    25261 cgcttagggg cttcattttc taagacaaaa taggcacaac cataactaca atactctaaa
    25321 aggtagtctt gtaaacgact gattttttca agtttttctt ctgttcggtc atccttgtaa
    25381 aaacctcgta ggcgaagctg ttcgttgctc cagtccccca cgatataatc aaacttggtt
    25441 aatacttctg aaaaacgctg attaaaagtc gtcacatcaa aggcatcctt gatattttca
    25501 accaaggaaa aagctatccc ttccgtttcg accttgtccc cgtgtaaatg gaactccgga
    25561 ccaggaaact tgttatagtt gtataattca ggtgcaattt cttttcgcat agatatcctt
    25621 tttccacgat tacttaatac tttattctac cataatttct agcagttagc acgtttctca
    25681 taaaaatgaa aaaagtctga cgattttgtc agaccagaat cttataacct aaaaaagaga
    25741 agaacaattc ttccctccaa ctatcattat ttagcagctg cgtacaattc atctacttta
    25801 ttccagttga ttactgaaaa gaaagctttg atatagtcag gacgcacgtt gcggtatttc
    25861 acgtagtaag catgttccca aacgtccaag cccaagattg gttttttacc ttctgagatt
    25921 ggtgtgtctt ggtttgctgt tgaagtcact tcaagtttcc cttctttgtt gacaaccaac
    25981 catgcccaac ctgaaccaaa acgagttgtt gctgctgcag tgaaggctgc ttggaattct
    26041 tcaaatgaac caaatgttgc atcgattgct gctgccagtt ctgctgaagg agctgttttc
    26101 tcgggagtca tcaattccca gaaaagagcg tggttcaagt gtccgccacc attgttgata
    26161 agtgcttgac ggatatcagc tgggatagat tctacatcag caagcaaggc ttcaaggtct
    26221 tcaccgattt cagggtgttt ttctaaagct gcattggcat tgttgacata agtttgatgg
    26281 tgtttgtcat ggtgcaaatg cattgtttcc gcatcgatgt atggttccaa agcgtcgtat
    26341 gcatatggaa gttctggtaa gataatagcc atctgtaata cctctttttc tttctatatg
    26401 aaaatgataa cgcaaacatt cacttttttc aagttttttg cttatagata aggaaatcac
    26461 tgacatactt tctaataaaa taagcaaatc agcaagaaac ccacgacaag ataatcctga
    26521 cgcgggttgt agtttcaaca aatgtcaatt gacctgacta gcaatctgta agagtgcctt
    26581 ttcaaaaagg aaaccttttt cataaagacc tgtcttaatc tgatagtctg tctcaatcaa
    26641 ataggaaata gcttgcttca gaaagctcaa agaaagtcct ctcgaatctc ttaatgcaaa
    26701 cttgatttga taaggatttg ggttacgtcc cagataacta cctaaactac ttgcaatctg
    26761 cgattctgtt tggccagact ccgccaaaat cttcacctga gtaaaagtcc gaaattgtcc
    26821 cagcatgact gcaatcagtt tgatttcatc ttccccttgc aaggtcaagt ctctcaccaa
    26881 atcgcgcgcc tgatccatct ttttagtcag aataaactga gttaaatcaa aaatattgtc
    26941 ctgcaaggtc ttgggaattg cgttaacaat atcctcttcc tcgataacag aatccgcctt
    27001 ataggactgt aaaaagagaa gatttttctg gatttcgcta aattgaaacc ccgacttgat
    27061 gaggagattt tcaaaagaat gattggtaaa ctgcagacct tgtttctgac tccacttttg
    27121 gaaatactgg cgcaattctt gttcttttac ttctactgca tcgaagacct tggcatcacg
    27181 cttaagtaat ttgactaacc gtcttttgct atccagcttt ccttctgcaa agattatcaa
    27241 cttagttgtt ggagaaggat tgtcaaggta ttcctcaaat gacttaagct catcatctgt
    27301 caaaaagcgt ttcttagcag tcgtgatatc cataaaataa tctaatatca cgattttctc
    27361 atccgcaaag aaaggaaggc tgaccaactc cagttccaca tccttgtaaa ctacttcttt
    27421 catatcaaag taggcaaagt tgaggtcagc agaatcatac ccaatctgtt tcaacatttg
    27481 actcttcatc acttcaaact gaccctgatc tgtccctgta aataggctca ggctcggtaa
    27541 atttgataaa gtcaacttct gactttcttc aatggctagc atcgactctc ctttcttcag
    27601 atttttcgat ttaatttagt caatatagcg caatttccca cggaaatctt ctaagctctc
    27661 gtagcctttt tccaccatga ttgctttcag ttcattggta atgcggtcaa aagcactgac
    27721 gccttctttg tgaagggtcg ttcccacctg caccatactt gctccacaga ggatgtgttc
    27781 aaaggcatct cgaccagtca gaacgccacc tgttccgata atttggattt gaggatttaa
    27841 acgttgataa aaggcgtgaa cattggctag agcagtcggt ttgatgtatt ctccaccaat
    27901 tccaccaaaa ccattcttag gccgaataac gacagattcg tcttctatat agaggccgtt
    27961 tccgatagag ttaacgcagt tgacaaactt gagcggatat ttgttgaaaa tagctgccgc
    28021 ttgatcaaag tgaacaatat caaaataagg tggcaattta attccaagag gtttggtgaa
    28081 gtaagcaaac acttctgcca aaatccggtc tgttgtctca aaatcatagg caatctgagg
    28141 tttacctgga acatttggac aggaaagatt tagctcagtc agaccacgaa aatcactctc
    28201 ttggactttt ttcaaaatag tatgggtttc ctctggagac atgccgacca gagataagaa
    28261 gaaagttcgg ttcgactctt tttcctgcaa atctaaaaga taatccaaat aatagtctaa
    28321 gccattattt ggcaagccca tagagttgat ggaaccaagt ggaacatctt ggtagcgtgg
    28381 ctcaggattc ccctgacgga agtccaaggt cgctgtctta gtaacaaagg ttcctgccgc
    28441 tgagtttttg acctcttcta actcctctat cgtcatacaa gccacacctg ctgcattcat
    28501 caagcaattg tcaaactcaa aaccagcaat ttgtgttttc gttgatacca tgattctaat
    28561 cctccagatt tcttttattg ctaatattat accataattt taattctagg tttactagat
    28621 tctgtggttc tatctattta ttcggaaaag aaagtctagt acagaagtca tgctatggaa
    28681 acagctagtg tattagaagt ttgaacaagg cttgggtaac agacttttga atgaagtcca
    28741 agcaacaagg agaaatctca accatgagtc cattccatga ctctgttgct ctagaaaacc
    28801 ttgcaatagt caagtgataa cgaataaaac tttggattga aatatcccca agattatcta
    28861 ttacgaggag aaatcttaac ctttatcatt tttaaagaaa tatagtaaaa tgaaacaaga
    28921 acaggagaaa tcgatcagga cagtcaaatt gattgctaac aatgttttag aagttgaggt
    28981 gtactattct agtttcaatc tactatacat gtaaatctct actttcgcaa aatggatttt
    29041 cagaacagta tcccagtata gttaaaaact ataaaaaaga gaggacgttc ccctcttaaa
    29101 atcttatttt actgcttctt tcaaagcatc taccttatcc aaacgttccc atggaagatc
    29161 aatatctgta cgtcccatgt gaccgtaagc cgatgtttga cggtaaattg gacgcttgag
    29221 gtccagcatt tggataatcc ctgcagggcg aaggtcaaag atttgacgag ccgctttttc
    29281 aagttgactt tcagctactg ttcctgtacc gaaagtatcg atacgaacag aaacaggttg
    29341 cgcaacaccg atagcatagg ccaactgcac ttctgccttc ttagcaaggc ctgctgcaac
    29401 gatattcttg gcaatatagc gagccgcata agaggctgaa cgatccacct tagtcgcatc
    29461 tttaccagag aaggcaccac caccatgacg agagtagcca ccataagtat ctacaataat
    29521 cttacgacca gtcaaacctg agtccccttg aggaccaccg attacaaaac gacctgtcgg
    29581 attgataaag aattttgtct tatcatcaag ataagaagat ggaataactt ctttgatgac
    29641 cttgtcaatc acatcttgat ggatttgttc attagtggcc tctggatcat gctgagtaga
    29701 aataacgact gtatctacac gtaccggacg gtcattttca tcgtactcaa ctgtaacttg
    29761 tgattttgca tctggacgga gatagctaat ttctccagac ttacgaagtt ctgccagacg
    29821 acgaaccaat ttatgactga gtgcaattgg caatggcata agctcttctg tttcatctac
    29881 tgcaaatcca aacatgagcc cttggtcacc tgctccaatc aagtccagtg gatcttgatc
    29941 agcatttcca cgaacctcca aggcttcgtt aacaccttga gcgatgtcag gagattgttc
    30001 caccaaagat gggtgtactc ccaccgtctc agcagaaaat ccatattctg tattggtata
    30061 accaatctct gcaatggtat cacgaaccac acggttaata tccacatagg catttgtaga
    30121 aatttcacca aaaacgtgga cagaaccagt atatacagct gtttcagcag caacgtgcgc
    30181 ctctggatcc tttgctaaaa tagcatccaa aatcgcatct gaaatttggt ctgcaatctt
    30241 atccggatgc ccctcagata cagattcaga cgtgaataat ttacgttctg acataaaaat
    30301 gtcccccctt aaaaaatatt gttatagagt tacaaagtac tgataggaaa actcttcgta
    30361 ataaatacct accatcttat cgggactata taactttatc attataccat ttttaatcgc
    30421 aatttgcagt ctttaatgta gtgtttcggt ttagatagtt cgttctcata aagcaaaaag
    30481 ttggagctca gtactccaac aatttctatt aaaatgtttg acgtttagct ttacgctctg
    30541 cacgaccgcg agcgcgattt tcagcacgct tggttttacg gcgcttttca tcaaccgccc
    30601 attgaatttt cttcttataa cccggtttga cttttttctt tttcttttta accaaaccaa
    30661 tcatttcgat atcaagttta tcttgttttt tctcacggtt ggcacgacga tcacggtcat
    30721 aggtatcttg aaattccccg tctttgacca tcttaggact aaacttgatt cccaatttct
    30781 ccaactcacg gatatccgag tcatcacttg gctgataaag ggtaatagct gtacctggta
    30841 ggccatttcg tccagtacga ccaacacgat gaacaaaaaa agataagtct tgcggaatgg
    30901 catcattgat gacatggctg acaccttcaa tgtcaatccc acgcgctgct aaatctgttg
    30961 cgacaatata ctcaaaatcc agattttgca cctgattcat gattcgcttg cgttcacgag
    31021 gggcaatatc gccatggatt tttgcaacct tcaaaccttg agaagtcaga tatgaatgca
    31081 attcatcagc acgcgtttta gtgttaacaa aaatcattgc caaatacggc tgcatcaact
    31141 gagtcaacca gtaaatttga gcattcttat catgtccctt ggtcgaaatc aaccaattat
    31201 caatggtgtc agaaataacc gttttagtct taattttctc cataacagga tttgataagt
    31261 attttttcaa gaatggttgc agtttttgtg ggatagtcgc tgagaagacc atgaattgca
    31321 agtcttttgg aagactgcca gcaatcttat caacagtttc caagaatccc atatccaagg
    31381 tcatatctgc ttcatcaaca acaaatgtct tggctttatg aatagctaaa tcaccagatt
    31441 taaccaagtc gtagatacgg cctggtgttc caataacaat atgaggctga ttgcttgcca
    31501 atttctcaat ctggcgagcc ttatccgtac cacccacata attaaccaca cgaacttcga
    31561 catctgagtg agctgaaatc tgacgcgcta cttggtaaat ttgagtagcc aactcacgac
    31621 tcggtgcagt aatcactgct tgtacactat cgctagcttc atctaattgc tggaaaatcg
    31681 gtaacaagaa agtatgagtc ttacctgaac ctgtttttga ttctcctact aggtcacgac
    31741 ctgccaaaac aataggaatc aacttgtctt gcacctctgt tggagttgta aattttaact
    31801 ccttcaaggc ttctctaata tagtttttaa attgaaattt cgtaaatgac ataacatcct
    31861 cgattctatc tatcttatca attataccat attttattcc attacagtag tctcacttat
    31921 ttaggctatt tccagtagct tctctagtaa gaaaaggctg gaattttata gttccaacct
    31981 cttttcagtt attatttcca gtttaatata gcattcaagc catagtgatc actcacttgt
    32041 ggactcttgt taccatcaaa tacgacatgt aaattttcca ccgctaactc tttggtagta
    32101 aagacataat cgattcgaag gggttcagtg ttccctttcc agccatcaat ttcaggcgga
    32161 acagtatagc taccactttt ctcttgagca acttcaaatg cgtcttgtaa gcctaatgga
    32221 ctagctaaaa tagcttggta accttcctga cctgctgggt tgttaaaatc tccagctagt
    32281 aaaagtggct tgttcaattt tttcaagaca gcctcaaatc gtgcccattc ttcttggaaa
    32341 cctttatccc accaagagag atgaacactg gcaactgcta gctccttgcc atcgactaca
    32401 gtttcagcta gggcaacacg gcgagtatga tagtctgttg gatcatccac atctgaaacc
    32461 aaaatttctc tggcttcaat aggtgtttta gacaagatag ccacaccttc gtggtagcgg
    32521 tcatagccga tatggttata agcccaggtc cagtagtaat ttttcccttg ctctaacaac
    32581 ttttcaacca agagtctaac ataatggtct tggtgaatag gctcagctgc tggcaaagct
    32641 tgataaaggt cattaacctc cacctctgac gaggtcatct cctgattgat ttcttggaaa
    32701 caaatcaaat catagtcctt ttcaagaata tcttcaagca aaatctggaa tttttcctct
    32761 gcttctttct ccatccaact gtgagtattg agtgttaaaa atttcattct tttctcccaa
    32821 aataagaggt tggaatacag cttccaacct caagtatatt acaattctac tttagcaact
    32881 gctgttttag ctgcaagaga acctgttttt tctaatttaa ctgatttaat tgcatcacca
    32941 tttgtgaaga caactactgt tgaagtttca cgtcctgctg cacggatagc atccaagtca
    33001 gctgtgacaa ggagatctcc tgctgcaact ttttgtcctt cagcaacatg aactgtaaat
    33061 ggtttacctt caagacttac tgtgtccaaa ccaatgtgaa ccaatacttc aagacctgct
    33121 tccgtcacaa taccaaaagc atgttttgtt gggaagatgc ttgacacagt acctgaaact
    33181 ggagatacaa tgtttccatt tgcaggttct actgcaaatc catcacccat cattttttga
    33241 gcaaatactg gatcctttac ttgttccaaa ccaacaactt gaccgtctgc tactgagtaa
    33301 acttcctcag taagatcttt gaagtgaaca gtgttttgtt gtgcttcagt catttggctt
    33361 ggaagagttt caggaatgat ttcacctgaa tcaaggatat cttggatatc agatttcaaa
    33421 atgtcagctt ttggaccgta gatagcttga accccttgtc ctttcatcac aagacccata
    33481 gctccttctg ctttccattg ctctgcattt cctactttat ctgcatcttt aacagttaca
    33541 cgaagacgag tcatacatgc atcaacatca acgatgttta cacgtccacc aagaaggttg
    33601 ataatgttta cagcttgaga gcctgctgca actttcactt cgctgctggt ttcttctgaa
    33661 ccttcagcag tttcgtagtt tccgttgcgc cctggagttg cgtagttgaa tttttgaatc
    33721 atgaagtttg cgataaagta catgattaca gcaaagagaa cagttaccca aacgaagtta
    33781 acgatatcca taccaatacc agcactgatt gcaataggtg tacgagtcaa gaactcgatt
    33841 gaaccgaatg agtgcatacg taggtttacg acgtcagcca tagcgaaggc agcaccttga
    33901 acaagtgagt aaacaagata cataggtgtt gcgatgaaca tgaacatgta ttcgattggt
    33961 tcagtaaccc ctgtcaagaa tgttgcaaga gctgttgcaa tcatcatacc tttgtattta
    34021 tgtttcttgt cagcatcaac attacggtag atagcaacaa tcacacccat caagataccg
    34081 aatgaaccga tcatttgtcc aactttgaaa cgagctggat gtactgtatc taacaagtgt
    34141 tgatattgac tagcatcagt acctttaagg tttacaaggt ctgttaccca tgcaagccat
    34201 agtgggtctt gaccgaatac ttgagtacct ttagctgcac cagttaaaat gtcataagta
    34261 ccaccaagag ctgtgtagtt cattgggata gtcaacatgt ggtgaagacc aaatggcaag
    34321 agcaaacgtt ccaaagtacc atacaagaat ggtgcaagaa ttggagcagt ttcttgtgag
    34381 ttggcaatcc agataccgaa gttattgata cctgtttgaa ctactggcca gaaagcagca
    34441 agtagaattg cagcgattgc tgaacgaaga ataactacaa atggtacgaa acgtttcccg
    34501 ttgaagaatg aaagtgcatc aggaagttta cggaagttgt agtatttgtt gtaagcagtt
    34561 gcccctacaa aacctgagat aatccctacg aataccccca tgttcaaggc tggagcttca
    34621 agaacactga taaagtaatc agcaactttg attgaaccac caaagaaagt agttaccata
    34681 gcatctggat ttttcaacat atcgcctgat acaccaaaga ttgtaccagt gatacggtta
    34741 atcaagatga aggcaagacc agcggcgaaa gcaccaccag cacgttcttt agcccagctt
    34801 cctccaatgg ctagggcaaa caaaatgtga aggttaccga taacccccca accgatttgc
    34861 tcaagaattc cacctgtgat gacaagtggt gtaaaggttg ggttaatcat cacgatagac
    34921 ttaccgattg aaatcatcaa accagcagcc ggcataaccg cgataactac catcaaagcc
    34981 ttaccgaatt tttgccaaaa ttcgaaagac aagacatttt tgaatgtatc tttcatcatt
    35041 caaatctcct ttatttttat ttaggcaaac gttttacgaa aacgtttgca ccttctataa
    35101 tttaattata ccactttaat tttttttgta aaggctttta taaaaaaatt acactttttt
    35161 ctaaaaaatt tctagtgagt caaatttcaa gttcaaatta gccatcaaga agtcttctct
    35221 agaggacttc tttggaagct cttttcttct acgcatctct tttcaaaaac tcttgtagca
    35281 aaaaaggaga ttttacaatc tcctcataaa agcagctatt ttacctaaat cttcaagaat
    35341 cggcgcatgg atattcctga tcccaatgaa ccaatgaaaa ccccaatcac aaatagtagg
    35401 gcaatcatca acggactaaa taaatctgga ctaatcatgg atagattttg ccctaccaac
    35461 gatttgttga cagattggta aacaatttga taaacaataa agaccaaaac agatggtgcg
    35521 atagctccca ataaaccgat aaaggctcct tctaacaaga acggtccacg gatataactg
    35581 tttttagctc cgaccaagcg catgatttga atttcgcgac tgcgggaaat aatggtaata
    35641 cgaatggtat ttgaaatcaa gaaaactgcg ataaaaatta acaaagcagc aatccctagt
    35701 ccccaaacac ggataaatga agctaacttg aagagtcttt ctgtattggc accgccatct
    35761 tgaacctcag agacaccttc aattttttta gcatcttcgg ctatagtttt tacatcattt
    35821 ggagtgtttg cctctacaat ataggcatca tagagaggat tggcatctcc ttcaaagatt
    35881 ttccagttat ctcccattat ctcggttaat ttttcatatt gttcttcttt acttgaaaag
    35941 gtaacacttt taaccgtaga catgttcttc aaagaatcat ataccttgtg gtagtcatta
    36001 tttgtaacag tttgaccttc tttttcaatt gtctgactat tatcttccac atcctttcgg
    36061 atataaacta ctacacggac attattttca atatctgtag ctagtttcgc tgtattgaaa
    36121 ataacagatg caaatattgc caccaaggtc aaagtaatca tgactgaact gacagcagct
    36181 actgtcatcc aaccatttcg tttcaaactt tttaaggctt caaataaatg gcgaaaaaat
    36241 ctactaatca tcgtatccat actctccttt tgattcgtca cgaacgacac ggccattttc
    36301 aatggcaatg acacggtggc gcaaggtatt tacaatctgg ctattatgag tcgccatcaa
    36361 aatagttgtt ccttgtaggt taatccgttc caagagattc ataatttccc atgaattatc
    36421 cggatccaga tttcctgttg gctcatcagc tatcaatact ttgggattat ttacaattgc
    36481 acgcgcaatc gcaatccgct gttgctcccc acctgagagt tcatttggga aagaacgaac
    36541 cttatgcttc aatccaacca agtccaaaac ttccatcact cgtcttttga tattacggcg
    36601 attttccccg attacttcca tagcgtaagc aatattttca tagacagttt tctttggtaa
    36661 caatttataa tcttggaaga caaccccaac actacgacgt agaagcggga catctttctt
    36721 tttgatctta accagattaa aaccagcaac tgatagactt cctttatcga tttttacttc
    36781 acgatacaga gaacgaataa aagttgactt ccctgctcct gaaggtccta cgatgtaagc
    36841 aaattccccc ggttgaacgc taaccgaaac accgcgtaga gcagtcgttc cgttgtcgta
    36901 ttttttaacg acatctctca tttcaataat tgacatgtga gttcctttct atcttagcta
    36961 attcgccact tgagataagc atcgataaaa ccatctaggt ctccatccat aaccttatct
    37021 acctgagcaa cctcatagct agttcggtga tcttttacca tagtataagg cgtgaagaca
    37081 taagaacgga tttgacttcc ccaagtgatc tcctttttct cacctttgag agaatctacc
    37141 tccgcagcct tcttctcttg ctccatttga tagagcttag cctgcaacat cttcatggcg
    37201 cgatctctat ttccatactg ggtacgatcc actgttgatt ggacaacaat tccagttgga
    37261 atgtaggtta aacgtacacc tgttgaaacc ttattgacgt tttgtccacc ggcaccacct
    37321 gaacggaagg tatccatctt gatatcatct tcacggattt ccacttcaat agtatcatcc
    37381 aattctggca tcacttctac agatgtgaaa gaggtatggc gacgtttggc agagtcaaat
    37441 ggtgagattc gcactaagcg gtgaacaccc atttctgact tgaggagacc ataggcatta
    37501 ggcccttcaa atgataaagt taccgactta ataccagcct catcacctgc ttggtaatcc
    37561 aacacttcca ctttaaagcc tttagcatta ccataacgag tatacatacg aagcaacata
    37621 tcaccccagt cctgcgcctc agtaccacca gaacctggat ggatttccaa gatggcattg
    37681 ttgtggtcat aaggttctga caagagtaga gtcatctcgt agctggtcat tatcttatca
    37741 agttcggcta actgcgctac cagttcatca tgcactgact cgtcttcagc caaaaaatcc
    37801 aataaaattt cgacttcatc ctgcaactct tccatcttat ggaaggtatt gtaagtgttt
    37861 tttaattcat ttaattcttg cgacattttt tgggccgcaa tattatcgtt ccaaaaatca
    37921 ggttctgtca tcttgttttc caagatggca atctcttcct ctagcccttc gaggtcaaag
    37981 agaccccctg aaagaagcta atttttcacg atttgcgtca attttctgac gaattactga
    38041 aatgtccata aatactcctt ttttacatta tttcattata gcatatttta tcatttcttt
    38101 ccatcttttg ctctaatccc cttttcatga aaaaagaagc ctttgggctt cccttcttac
    38161 aagacttttg ctgaagtgcg aacgatttct tccacttgaa taccatttgc ttcaaatttt
    38221 tctttcaagg ctggtaaatc aattgatcca tcgatttgca cttcgataat caccttacca
    38281 tccttacgcg gaatattgac tgtatgggag atattcaaat tttcttctac aatcaaagaa
    38341 acaatttttc caagaacacc aacttcatct tctgtaacaa agcgtacacg aatcccttct
    38401 tcgccataac ctgcaatttc aagaaaggct tggaaaacgt cacggtcagt aataactccg
    38461 tatacttgat ggttatctac gacagggaga ataccaatct tatttttcaa catcagataa
    38521 gttgcatctt ctagactagc atagcctgag acagtgacaa catcgcgaat catgacatct
    38581 tttacttttg tcttattcag aagataattc atctcataga tagaaagact tgttgcttta
    38641 gatggacttg cttgtgcaat ggttccctca gtcaccaaac caaccaattg atcattttcg
    38701 ataacaggca agcgatgcaa ttcttgctct ctcatcaaat ctgctgcatg agatactgtt
    38761 gtatctggac taatataaac taccttgcgg gtcataaaat ctttaactgc catgagactt
    38821 ctccttttct attcttatcc ccattataca atctttttgt aaatctatca aacgcttaca
    38881 tttctttttc gaaattcaaa aaagtatgaa taagctagca aaaagagctc tgaaatagag
    38941 ctctgtgaat gaaggtaaga aatttttcat tcgatttttt caattattag aaattaagct
    39001 ttcaatgtag atgcatattt gtttgcaatc tctatccacc gactaaaaag gtccccagga
    39061 ctatattgat gattacttcg taatctccat ctgccggcta aaacaatcct ctggatttga
    39121 tgattgcttc gcaatcttta tctgcaacct aaactagtct cccagactat aatgatgatt
    39181 acttcgtaat cttcatctgc cgactaaaac aatccactgg attgttttag ctacctagat
    39241 atgcttttct gacttcttct gatgaggcga gttcttttcc tgttcctgat aggacgattt
    39301 tccctgtttc cagtacatat cctcggtcag agattgcaag tgctttattg gcattttgtt
    39361 caatcaagag gacggttgtt ccttgcttct gaatatcttg aatgatatca aaaatctctt
    39421 ggatgaagat tggggcaagt cccattgatg gttcatctaa aagaagaagt tttggtgttg
    39481 acataagagc gcgtcccatg gcaagcattt gttgttcccc tcctgaaaga gtagctgcat
    39541 cttggttctt acgttcttca agacgaggaa agcgtgagaa aaccttcttc aagttagctt
    39601 gattttcttc acgatttttc tttaagaaag ctcccatttc aagattttcc ataacagtca
    39661 agccaggaaa gacgtggcgt ccttctggaa cttgtgaaag accacctgcc acaattttct
    39721 gagctggcat tttttggatt tcttgaccta aaaattcaat ctttcctgaa cttggtcgaa
    39781 ccaaacctga caaggtgcga agaatagttg tcttacctgc accgttggca ccgataaggg
    39841 aaacaacttc tccttcatta acttcaaagc ttacatcacg gactgcttgg atcataccgt
    39901 aatgcacaga aagattttca acttttaaca tagacattag gcttcacctc ctagataagc
    39961 ttcgataacg cgtttattgg tcttaatttc gtctggagtt ccttgagcaa ttaaacggcc
    40021 atattcaagt acgtagatac gttctgttac ttccatgacc agattcatat cgtgttcaat
    40081 caacatgatt gtaatcttaa attcatcttt gatacgacga attaactcag tcaattcggc
    40141 tgtttcctgt gggttcatac ctgctgctgg ttcatctaag aagagaattt taggttccgt
    40201 agcaagggca cgaacaattt ccaaacgacg ttgttgtccg taggaaagat ttttagcaag
    40261 agtctctgca tcaccatcta aatcaaagat tttcaacaat tccaaagctt tagcctttaa
    40321 ttctttttca ctcttgtaaa aagctggtaa gcgtaagaaa ctagtaaaaa catgttgttt
    40381 gtgatggttt ccaaaagcaa tcaaaacatt gtctaaaact gttaaatctt taaagagacg
    40441 gatattttgg aaagtacgtc caagtcccaa agaggcaatc ttataaggtg atttcccatt
    40501 caaaaggtga ccatctaggg ttactgttcc ctcgcttggt tcataaacac cggtcaaaag
    40561 gttgaaaagg gtggttttcc cagctccgtt tggaccgatt aatccaacca gttccccttc
    40621 gttcaattca agagtcacat ctccaacagc tgttagacca ccaaaatgtt tggttaactg
    40681 ttttacttca agtaatgcca ttagttttgt tcctccttct tagatttttt aaagaaacgt
    40741 gataggctca gttcccacgt tccaaggagt ccacctggtc tgaaaatcat taccaatacc
    40801 aaggccaaag cgtaaataat catacgcaca ctagcaacat cttggagaag catattcaaa
    40861 attcccagaa caatagccga aacaatcgca cctgtaatgg aaccgagtcc accaaataca
    40921 acaataatca aaacgttgat tgagttgatg aaggtgtaat ctttcggtac aacagacccg
    40981 ataaatcctg cctgaagtga cccagcaata cttgcagtaa tggcaccaaa gacaaaagcg
    41041 atgattttaa ttttagtcgt attaacccca actgactcag cagcgatttc atcttcacga
    41101 acagagaggg ttgaacggcc aattgggcta cgcaagaagt tcaaggttgc aatggttgta
    41161 atcacgacaa agaagtaaac catttgccaa gttgtaaagt taggaatccc taagatacct
    41221 gccgcaccat ttgtaagact tccaccattg atgataaaga tacggataat ttcagaaaca
    41281 cccagagttg ctaccgcaag atagtccccc ttcaagcgca aggttggaat gccgacaagt
    41341 aaggcaactg ctcctgaaag caaagcccct acaagcatag ctccaaagaa ggcaccgtag
    41401 gttggtgatt tagaaccaat aatagctgct gcataggcac caatcgccat gaaaccagca
    41461 tgaccaagtg aaaattgtcc tgaaaaacca acgattaagt tgagaccaac agccaaaata
    41521 atattaattc caatttgttg taaaatctgt acatagaata gattaagtac tccgactgaa
    41581 accagtacac taatcaagct atagccagct aacaaaagga gtaaccatag aatattaact
    41641 tttaaatttt ccttcatcgt ttacaccttc tctttcacat tcttaccaag gataccagct
    41701 gggcggacaa tcaagatcaa caacaagatt ccataaacaa tggcatcacg gaaatctgac
    41761 atcccaaagg ctgtcgcaaa ggtttccaat agaccaatca caaagccacc aagagcagca
    41821 ccaggaataa ttccgatacc accaagtact gcggcaacga aagatttaag acctggagta
    41881 acccccatca aaggctcaag agagttataa taaagagcaa tcagaacacc agccgcaccc
    41941 gcaagagcag aacccaaagc gaaggtaaag ctaatcgtac ggtttacatt gatccccatc
    42001 aattgcgccg cgtcgctatc tactgatact gcacgcatgg ctttccccat cttagtcttt
    42061 tggacaatga cttgtaacaa aatcatcaaa atcaaggaaa tggccaaaat cattaactgc
    42121 acatttgtta agctaattgg tcccaaatca tatcgaactg tttgaatcgc ttgagggaag
    42181 gcacgggtat tggcaccaac cagatagacc attccatact ccaataggaa agaaacccca
    42241 atagccgtaa tcaaaacagc aatacgagta gagtggcgca aaggtcggta agcaagaaac
    42301 tcaatcacga caccaagaat agctgtcgct agcatagcta caataagcgc tacaaagaaa
    42361 ttcatttgga aagaattgat caagaaataa ccgataaagg ctcccatcat ataaatatca
    42421 ccatgggcga agttgatgag cttgataatt ccgtaaacca tggtatatcc tagggctaac
    42481 agcgcgtaaa cactacctag aatcaaacca tttacgagtt gttggagcat aagattcact
    42541 ctttctattt ataattccga ggggtttccc tcactttttg ataggttctt atactcaatg
    42601 aaaatcaaag agcaaactag gaaactagcc gcaggttgct caaagcactg ctttgaggtt
    42661 gtagataaga ctgacgaagt cagtcacata tataatccaa ggcgacgttg acgcagtttg
    42721 aagagatttt cgaagagtat taaatatcga aacagggagt gagtcaaagg ctcattccct
    42781 atttcaacat ttttctatta tggttttaca acttctgctg cttcaacttt accattgttc
    42841 atggtcatca tgtaagcagt tttgactgtg ttgtggtctg catcgaagct tgtttgacca
    42901 gttacacctt caaaatcttt tgttttagca aggttatcct tgatttcacc tgaattttta
    42961 gcaccttttg ctgcgtttgc tacaaggtga actgaatcat aagccaaggc tgcaaatgtt
    43021 gaaggctctt cattgtactt agcacggtaa gcgtcaagga aggctttagc tttagctgaa
    43081 acttctacag tagttgagaa gcctgagata aagtagatgt ttgatgcttt ttcagcagtt
    43141 gcttgttgta caaactcctc accgttgaat ccatcaccac caacgattgg tttgtcaatt
    43201 cccatgccac gcgcttggtt tacaatctta ccagcctcat tatagtaacc aggaacaacg
    43261 atagcatcaa agtctttccc tttcattttt gtaagggctg cttgaaagtc tgtgtcacct
    43321 gctacgaaag tttcatctgc aacgatttca cccttgtatg actcgcggaa agatttggca
    43381 atccctttag catagtcact ggcattgtca gtgtaaagaa caactttctt agcatttaat
    43441 ttttcagaaa catagtttga gataattttt ccttggaagc tatcttggaa agttccaata
    43501 aagaggtaat cttgaccttt agtcaatcca tcttgagtcg cacttggtga gatcaatgga
    43561 acacctgctt ttgtagcgtt cgctaccgca gctgcagtcg caccagatgt cgcaggtcct
    43621 acgactgctg atactttaga ttgggttaca aggttagttg taactgaagc agcctcagct
    43681 gtttcagact tattatcttt atcgactact tcgatttgtt ttccatcgat accacctgcg
    43741 gcattgattt catcaacagc caattgggca cctttttgtt cagctgttcc gtatgcagct
    43801 aaagaacctg attcttcaaa gttaaacccg attttaattg tcttttcctc tactgagtta
    43861 ccagcagtgt tgactgctcc agacttcact tctccacagg ctgcaagaag tgctacactt
    43921 gcaagcgcca caaacgatag ggcaaatttt ttcttcatct ttttgtctcc ttatttctta
    43981 aacagtctgt taaaaatata ccgaattatc agaaaattgt caatgttttc cttgaacttt
    44041 ttcgatgata acgttttcct atcgataaag attgcccaca aagggtgttt ccaactcttg
    44101 gatatgacaa accctaactt ttttaataaa tttttccttg ctcaagcgtc cgaccaattg
    44161 ctccacttct tgagttggaa catagagttg taagtaacga tgtttcttgg aatgataggt
    44221 aatatctcca taatcctgca gttttttggc atcacgatta tagtaaagat agataatcaa
    44281 gccagagcga ttgacttttt caaacatgat aaatcctctt tctaagaaat ctctccctat
    44341 tataccaaaa aaagcaaacc cagtcgagtt tgccttctat catcattagt tcaatgaatt
    44401 gttggccata atttcatcaa taaagccata ttcaagtgtt tcctgggcgc tcatccagtt
    44461 atcacgttct gcatctgcat ggactttttc cattgactga cctgaatttt cagccaagat
    44521 tttttccaag gtattacgag ttttgagcaa gtgttctgca gcgatagcca tatcagtttg
    44581 ttgggtacca ccacctgtac cgcccattgg ttggtgaatc atgtattcag catttggaag
    44641 catgaaacgt ttgccttttg ctccacttga tgcgatgaca gtccccatag atgcagccat
    44701 tcccataaca atggtttgga catctgcctt gataaagttc atggtatcta cgattgccaa
    44761 accagctgaa acagaaccac ctggtgtatt gacataaagg taaatatctt tcgtactatc
    44821 ttgggcatcc aagaaaagca attgggcaat aacagagtta gccatattgt cttcaaccgg
    44881 acctgtcagc ataatgatgc ggtctttgag aagacgtgag taaatatcgt aagaacgttc
    44941 tccacggctt gtttgttcaa taactacagg aatcattcat ttctcctttt gagttttaat
    45001 tttgttggtc aaatgactga agataagact attataatat cttggtcaaa aaaggtcaaa
    45061 tttttgctct gctttcatta gacagaaaca aaaacccaac ctcctttcgt gactagaaat
    45121 acttttccaa gtcattcttc ttttcgatct tattttgtac cgaacaagcg gtctccagca
    45181 tctccaagac ctggaacgat ataaccgtgt tcattcaaac gttcatccaa ggctgctgta
    45241 aagatttcta catctggatg agcttcttga agggctttta caccctctgg agcagataca
    45301 aggcagacaa atttgatatt tgatgcgcca cgttttttaa gagaatcaac agccaagatt
    45361 gctgagccac ctgttgccaa cattgggtct actacaaaaa tttgacgttg gtcaatgtcc
    45421 tcaggcaatt tcaccaagta ttcaactggt tgaagtgttt cttcatcacg gtacataccg
    45481 atgtggccaa ctttagcagc tggaaccaag ctcaagagac catcaaccat cccgatacct
    45541 gcacgcaaga ttgggacgat ggccaatttc ttacctgcca attgtttttg aactgttttt
    45601 gtaattggtg tttcgatttc cacatcttct agtggaagat cacgaagtac ttcatacccc
    45661 atcaacattg caatctcatc tactagctca cgaaaagctt ttgtagaagt atctgtacga
    45721 cgcaagattg acaatttgtg ttgaatcagt gggtgattaa taacttcaat ttttcccatt
    45781 tttggaattc cttctttcaa tttattcttt ttattatacc aaaaaacggt ttaaaaatct
    45841 ttctaaacca tttatttttg ataattttta cattagatca gcctctttaa gagctgtctg
    45901 tactgtctca agtggtaaat gggtcaattc tgtccctttt tcttgataaa ggtattgggc
    45961 gtagtcgtcc attcggtact ggttgatata aaccacacgc ttgcagccga cctgaagcaa
    46021 ttgttttgta cagttgagac aaggaaaatg ggttacatag gctgtaaagc ctttgggaac
    46081 accacgctca gcaccttgaa ggatagcatt gacctcagcg tgaagggtgc gaacacagtg
    46141 gccttcaatg accaaacatt cgtgatcaat acaatgctca gtccctgaca ccgaaccatt
    46201 gtaaccagtg gaaataacct tattatcttt taccagaatc gcgcccactt tagcacgttt
    46261 acaagtggaa cgattcgcaa ttagtagggc ttgggctgca aaatactcat cccaggccag
    46321 tcttttttca gtcatctctt ttctcctttt tctctatttt ttaaaaaatg gtaaacctaa
    46381 atctgcaatc ttttcagctg gtaccttcat gccatccttg atccatttta gaaggacaga
    46441 gacaatggct gagctccaga aggaatgaag ataagagctg acaccttttg atttcccatg
    46501 gtatttttct agaaattcct gcatggcttg gacaaagatt ttttccagat ggtaatccaa
    46561 ggccaattga atcactctag cttcctttct ggcctcccgg aaaaggtgaa cccaaaccaa
    46621 ataaaggtct gtctttaaat cgtaatgatg cagctgttcc ataatattgt ggacagttcg
    46681 tttaaagacg ctctctaaaa tttcctcttt ggagtcataa ttgcgataaa aggccgcacg
    46741 cgaaacacct gcacgtttga ccaattcaga aatactaatc ttggtcagct cctttttttc
    46801 caagagttgc aagagggctg tttcaatggc ttctctggtt aataaattgg attcttggtt
    46861 tgattttctg agattttcaa gagacttttc agagattcta cgttcagaca taacattttc
    46921 tttctacttg tcacaacaga cggatgatgc ttttgtttca agagttttca tgatataatt
    46981 gtaaaaaaag acagaacctt tgtcaatgta taactgacaa agatggagaa tttctatgac
    47041 ttggaaaatt attgctgact ctggttgtga ttatcgtcaa ctgccaacac cagctattaa
    47101 cacaaccttt gtaagtgtcc ccttaaccat tcaagtagct gatcaggtct ttgttgatga
    47161 cgccagtctc gatattgacc aaatgatgga aaccatgtat gcaactgcag aagcttcaaa
    47221 atcggcttgt ccaagcccag atgactattt gcgagcattt gaaggtgcca aaaacatttt
    47281 cctagtaacc atcacaggta ccctttctgg cagtcacaat agtgctcaac tagcaaagaa
    47341 tatttatctg gaagaccatc ctgacactaa gattcatgtg attgatagtt tatctgctgg
    47401 tggtgaagtt gacctactcg tagaaaaatt gaatgacttg attgaccagg gcttgtcttt
    47461 tgaagaagtg gttgaagcta tcaccgccta tcaagaaaaa actaagttgc tctttgtcct
    47521 agccaaagtc gataacttgg tgaagaacgg ccgtttgagc aagcttatcg gtacggtcgt
    47581 tggccttctc aacattcgta tggtcggaaa agctagtgaa actggaactc tcgaattgct
    47641 acaaaaagca aggggatcaa agaaatcagt tcaagctgcc tatgatgagt tagtaaaagc
    47701 tggatatgct ggtggccgta ttgtcatggc ccaacgcaat aacgaaaaat gttgtcaaca
    47761 gctctcagag cgaatccgtg aaaccttccc acaagcggat attaaaattc taccaacctc
    47821 tggtctctgc agtttctatg cagaagaggg cggtttgctg atgggctatg aaattgatta
    47881 attgcattct tgacaagagg tgaccatcat ctcttgtttt tttgtggtac aatagagcta
    47941 tgaaacattt tgatactatt gtcatcggtg ggggacctgc tggtatgatg gctacgattt
    48001 ccagtagctt ttatggacag aaaaccctcc tcatcgaaaa aaatcggaaa cttggaaaaa
    48061 aattagctgg gactggtggg ggacgttgca atgtgaccaa caatggtagc ttagacaacc
    48121 tgctagctgg aattcctgga aacggacgct ttctttacag tgttttctcc cagttcgata
    48181 atcatgacat catcaacttt tttacagaaa atggtgttaa acttaaggtc gaagaccacg
    48241 gacgcgtctt tccagccagt gacaagtctc ggactattat cgaagctttg gaaaagaaaa
    48301 tcactgaact aggtggtcaa gttgctactc aaatagaaat cgtttctgtt aaaaaagtag
    48361 atgaccagtt tgtccttaag tcagcggatc aaaccttcac ttgtgagaaa ctcattgtca
    48421 caacaggtgg taagtcttat ccttcgactg gttcgactgg ttttggtcac gagattgctc
    48481 gccattttaa gcataccatc accgatcttg aggctgctga aagtccttta ttaacagatt
    48541 ttccacataa agccttacaa gggatttctc tggacgatgt gaccctaagt tatggtaagc
    48601 atgtcatcac tcatgattta ctctttaccc actttggttt gtcaggtcct gctgccctac
    48661 gcatgtctag ctttgtcaaa ggtggggagg ttctctcact cgatgttttg cctcaacttt
    48721 ctgagaagga cttggttaca tttctagaag aaaatcggga aaaatccttg aaaaacgctt
    48781 taaaaacctt gttaccagaa cgcttggccg aattttttgt acaaggatat cctgaaaaag
    48841 tcaaacagct gactgaaaag gaacgagaac agcttgtcca gtccattaaa gaacttaaaa
    48901 ttcctgtaac tggaaaaatg tcccttgcaa agtcctttgt taccaagggt ggagtcagtc
    48961 tcaaggaaat caatcctaaa acccttgaaa gtaagctggt acctggcctc cactttgcag
    49021 gcgaagttat ggatatcaat gcccacacgg gtggctttaa catcacttct gccctctgta
    49081 ccggctgggt ggcgggaagt ctgcattatg attaaagatt aaaggttgtg aagaatgaac
    49141 agaagagagg cagtcgaatt tgttaacatg tgtatgatta aaaacggaga taaggtcctg
    49201 gtccaagacc gagttagtcc cgactggcct ggcattactt ttcctggtgg tcatgttgaa
    49261 cgtggcgaat cctttgtcga tgctgtcatt cgtgaagtga aagaagaaac tggtctgatc
    49321 atttccaaac cccaactctg tggtatcaaa aactggtatg acgacaagga ttatcgttat
    49381 gtcgtccttt tttacaagac agaacacttt actggtgaac tccagtcttc agacgaaggg
    49441 aaagtttggt gggaggactt tgaaaatctt tctcatctaa aacttgcaac cgatgatatg
    49501 tctgatatgc ttcgtgtgtt tctagaagaa gatctcagtg aattctttta ctacaaaaac
    49561 ggtgacgact ggctttatga tttgaagtaa aaaataggct aggaaattcc tagcctattt
    49621 tttctgcatt tgtctgaacg taagctgcaa tggcatctga cgtgtactgg gctgttccag
    49681 aaccaaactt gtcaatgttt tccttaaact ctgggttata gacgtaacct ttaccgatat
    49741 gaccgaatac ctcaatagag cagtcaaatc cataagtgcg aatggcttgc aagagcttgg
    49801 ctgcttgctc ttggttttcg gttgctgttg caggtaaacc aacttgaaga ttttgtgcca
    49861 aagtttgaaa gacttggtta aaggcggccg tagcctcgtc ttcgtgacct ttttggcgtt
    49921 cgagcgcttg tcccatgact tcttgaccat atttctctac cgcttcttgg tggtattttt
    49981 gattgtcttg atagctaaat cccgtgaatt tttcctcaat ggtcattttt ctttctcctt
    50041 tttgttcttg aatagttttt tgcaaggtgg aaatcaaggt atccagatgt tgcctttcgc
    50101 gagttagata gtccaactgc ctagtcaaat ggggcaataa atctgtcctt tcttccttta
    50161 acagctctgc tattttctct aaagaaaagc ctagatattt gtagtaaaga atgacctgaa
    50221 ggcgttccaa atcctcttga ctgtaggttc gatagccgtt ttccgacttt aaggggacca
    50281 agagtcctat cttgtcatag tgatgcaggg tcttgacaga gatacctgaa agctgcgcag
    50341 cttcttttat atggtacatg atttcctcct tacaatgata gtataacccc tccccttagg
    50401 tcagagtcaa gcgtttttga gaaaattttt taactttttt gagaaaggtg tgaaaacttg
    50461 aaaatgattt tcttgacaga ccttagaaaa catgatagga tagtcaagtc tatcaatcaa
    50521 acagaaggct atttgacaac tcaagtagct ttttcttatt ttgaaaaagg agatcagagt
    50581 ttaactatgt cagaaaaatc acaatggggg tcgaaacttg gttttattct agcatctgct
    50641 ggctggccat cgggcttggt gccgtttgga agtttcccta catgactgct gctaatggcg
    50701 gtggaggctt tttactaatc tttctcattt ccactatttt aatcgatttc cctctcctgc
    50761 tggctgagtt tgcccttggc cgtagtgctg gcgtttccgc tatcaaaacc tttggaaaac
    50821 tgggcaagaa taacaagtac aactttatcg gttggattgg cgcctttgcc ctctttatcc
    50881 tcttatcttt ttacagtgtt atcggaggat ggattctagt ctatctaggt attgagtttg
    50941 ggaaattgtt ccaacttggt ggaacgggtg attatgctca gttatttact tcaatcattt
    51001 caaatccagc cattgcccta ggagctcaag cggcctttat cctattgaat atcttcattg
    51061 tatcacgtgg ggttcaaaaa gggattgaaa gagcttcgaa agtcatgatg cccctgctct
    51121 ttatcatctt tgttgttatc atcggtcact ctctcagctt gtcaaatgcc atggaagggg
    51181 ttctttactt cctcaaacca gacttttcaa aactgactag cgctgatctc ctctatgctc
    51241 tgggacaatc tttctttgcc ctctcactag gggttacagt catgttgacc tatgcttctt
    51301 acttggacaa gaaaaccaat ctagtccagt caggaatctc catcgtagcc atgaatatct
    51361 cgatatccat catggcaggt ctagccattt tcccagccat gtcagccttc aatatccagt
    51421 ctgaaggggg accgagcttg ctctttatcg tcttgcctca actttttgac aagatgcctt
    51481 ttggaaccat tttctacgtc cttttcctct ttgcgactgt cacttcttct gtcgtgatgc
    51541 tggagatcaa tgtgggcaat atcaccaacc aggataacag caaacgtgcc aaatggagtg
    51601 ttattttagg aattttgacc tttgtctttg gcattccttc agccctatct tacggtgtca
    51661 tggcggatgt tcacattttt ggtaagatct tctttgacgc tatggacttc ttggcttcca
    51721 atctcctcat gccatttgga gctctctacc tttcactttt tacaggctat atctttaaaa
    51781 aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa ggactgttcc
    51841 aagtctggct cttccttctt cgtttcttcg tttcgtcatt ccaatcatca tcattgtggt
    51901 cttcattgcc caatttatgt aatcaaaaag gacttgagta gtgaactcag gccctttctt
    51961 tttatggatg gctaacaatc aattccaaat cttgcccttc tagagtccaa gattcaacat
    52021 cacttggtag gataaagtgt ctcccttttt ggattggata gtttttcccg tcaacagtta
    52081 gttgaccttg accagccaag acactcaaca agctgtagtc agctgtcttt tcaaagttaa
    52141 cttttccagt aatttcccat ttgtaaactg cgaagaaatc attggataca aggagagtgg
    52201 aacgtagatc atctgctttg attgtcactg gacggctatt tgcgggttca ccaatgttca
    52261 agacatcgat agatttttca aggtgaagtt cacgtaaatt gcccttgtca tccttacggt
    52321 caaagtcata gacacggtaa gtggtatcgc tagactgctg ggtttcaaga atcaagatac
    52381 ccgccccgat agcgtgcatg gtaccgcttg gtacatagaa gaaatctcct gctttaactg
    52441 gcacttttgt caacagcgca tcccagttct tatcctcgat ttgctggcgg agttcttctt
    52501 ttgacttggc attgtgaccg tagataatct ctgaaccttc atctgctgca atgatgtacc
    52561 aacattctgt ttttccaagt tcgccttcat gctcgagtcc ataagcatcg tctgggtgaa
    52621 cttggacact gagccagtcg ttggcatcga ggatcttggt caaaagtgga aatacaggct
    52681 caggacgatt gccaaataat tcacggtgtt ccgcatacaa agtagcaaga tctgttccct
    52741 cgtaacgacc attggcaact ttagaaacac catttagatg agctgagata gcccagtact
    52801 ctccgacttt ttcacttggg atgtcgtagc caaactcatc acgtagcttg gtaccacccc
    52861 agattttttc ttgcataact gattgtaaaa ataatggttc tgacatctta atctcctgtc
    52921 tgatttttct cccctcatta tagcaaaaaa agagttccat ttgaactctt ttttacatct
    52981 tataaagcag ggagaagatt ttataaaaat agtaaacaaa tgtgctctac tcgatgctta
    53041 caccattgct atcaatgaca tccttgtacc aatagaagga cttcttcttg ctacgtttga
    53101 gagtcccatt tcctacatta tctcgatcta catagataaa gccatagcgc ttattcattt
    53161 cccctgtgcc agctgaaacc ggatcgatac agctccaagt cgtataacca agcaagtcaa
    53221 ccccgtcttg gtaaatggca tctcgcatgg ccttgatgtg ggcctctaag taagtaatcc
    53281 gatagtcatc tgctacataa ccattctcat ccggtgtatc catagcaccg agtccatttt
    53341 ctacgataat acta
//
LOCUS       DAVLIK010000009        51936 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLIK010000009 DAVLIK010000000
VERSION     DAVLIK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51936
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.009"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(138..1499)
                     /gene="dnaA"
                     /locus_tag="VXE87_000559"
     CDS             complement(138..1499)
                     /gene="dnaA"
                     /locus_tag="VXE87_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0842154.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1712..2470)
                     /locus_tag="VXE87_000560"
     CDS             complement(1712..2470)
                     /locus_tag="VXE87_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0842155.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2528..3709)
                     /locus_tag="VXE87_000561"
     CDS             complement(2528..3709)
                     /locus_tag="VXE87_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0842156.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3892..4371
                     /gene="rlmH"
                     /locus_tag="VXE87_000562"
     CDS             3892..4371
                     /gene="rlmH"
                     /locus_tag="VXE87_000562"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0842157.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4415..4488
                     /locus_tag="VXE87_000563"
     tRNA            4415..4488
                     /locus_tag="VXE87_000563"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4449..4451,aa:Arg,seq:tct)
     gene            4653..4778
                     /gene="comC"
                     /locus_tag="VXE87_000564"
     CDS             4653..4778
                     /gene="comC"
                     /locus_tag="VXE87_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0842158.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            4799..6124
                     /locus_tag="VXE87_000565"
     CDS             4799..6124
                     /locus_tag="VXE87_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0842159.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFVSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            6121..6873
                     /locus_tag="VXE87_000566"
     CDS             6121..6873
                     /locus_tag="VXE87_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0842160.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            6925..6996
                     /locus_tag="VXE87_000567"
     tRNA            6925..6996
                     /locus_tag="VXE87_000567"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6958..6960,aa:Glu,seq:ttc)
     gene            7002..7075
                     /locus_tag="VXE87_000568"
     tRNA            7002..7075
                     /locus_tag="VXE87_000568"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7036..7038,aa:Asn,seq:gtt)
     gene            complement(7116..7658)
                     /locus_tag="VXE87_000569"
     CDS             complement(7116..7658)
                     /locus_tag="VXE87_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0842161.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7837..8604
                     /locus_tag="VXE87_000570"
     CDS             7837..8604
                     /locus_tag="VXE87_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEV0842162.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLNKLVSGSNTLTQKSSRLTAGVG"
     gene            8689..9369
                     /locus_tag="VXE87_000571"
     CDS             8689..9369
                     /locus_tag="VXE87_000571"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV0842163.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVLVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
     gene            complement(9470..12022)
                     /locus_tag="VXE87_000572"
     CDS             complement(9470..12022)
                     /locus_tag="VXE87_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0842164.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTIPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12084..13706)
                     /locus_tag="VXE87_000573"
     CDS             complement(12084..13706)
                     /locus_tag="VXE87_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0842165.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            13912..14937
                     /gene="trpS"
                     /locus_tag="VXE87_000574"
     CDS             13912..14937
                     /gene="trpS"
                     /locus_tag="VXE87_000574"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0842166.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFTKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            15089..16567
                     /gene="guaB"
                     /locus_tag="VXE87_000575"
     CDS             15089..16567
                     /gene="guaB"
                     /locus_tag="VXE87_000575"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0842167.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(16618..17715)
                     /gene="recF"
                     /locus_tag="VXE87_000576"
     CDS             complement(16618..17715)
                     /gene="recF"
                     /locus_tag="VXE87_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0842168.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNRN"
     gene            complement(17718..18086)
                     /locus_tag="VXE87_000577"
     CDS             complement(17718..18086)
                     /locus_tag="VXE87_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0842169.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SCRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            18245..19495
                     /locus_tag="VXE87_000578"
     CDS             18245..19495
                     /locus_tag="VXE87_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0842170.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSEFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGISSADFKGWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            19492..20775
                     /locus_tag="VXE87_000579"
     CDS             19492..20775
                     /locus_tag="VXE87_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0842171.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            20817..21638
                     /locus_tag="VXE87_000580"
     CDS             20817..21638
                     /locus_tag="VXE87_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0842172.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            21649..22194
                     /gene="pgsA"
                     /locus_tag="VXE87_000581"
     CDS             21649..22194
                     /gene="pgsA"
                     /locus_tag="VXE87_000581"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0842173.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            22191..23018
                     /locus_tag="VXE87_000582"
     CDS             22191..23018
                     /locus_tag="VXE87_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0842174.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPGELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            23003..23842
                     /locus_tag="VXE87_000583"
     CDS             23003..23842
                     /locus_tag="VXE87_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0842175.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            23835..24629
                     /locus_tag="VXE87_000584"
     CDS             23835..24629
                     /locus_tag="VXE87_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0842176.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            24688..25506
                     /gene="mreC"
                     /locus_tag="VXE87_000585"
     CDS             24688..25506
                     /gene="mreC"
                     /locus_tag="VXE87_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0842177.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            25506..26000
                     /gene="mreD"
                     /locus_tag="VXE87_000586"
     CDS             25506..26000
                     /gene="mreD"
                     /locus_tag="VXE87_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0842178.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            26094..27272
                     /locus_tag="VXE87_000587"
     CDS             26094..27272
                     /locus_tag="VXE87_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0842179.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            27496..28275
                     /gene="rpsB"
                     /locus_tag="VXE87_000588"
     CDS             27496..28275
                     /gene="rpsB"
                     /locus_tag="VXE87_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0842180.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            28354..29394
                     /locus_tag="VXE87_000589"
     CDS             28354..29394
                     /locus_tag="VXE87_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0842181.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            29641..29964
                     /gene="tnpB"
                     /locus_tag="VXE87_000590"
                     /pseudo
     CDS             29641..29964
                     /gene="tnpB"
                     /locus_tag="VXE87_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(30105..30413)
                     /locus_tag="VXE87_000591"
                     /pseudo
     CDS             complement(30105..30413)
                     /locus_tag="VXE87_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            30404..30802
                     /locus_tag="VXE87_000592"
     CDS             30404..30802
                     /locus_tag="VXE87_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0842182.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(30999..31919)
                     /gene="cysK"
                     /locus_tag="VXE87_000593"
     CDS             complement(30999..31919)
                     /gene="cysK"
                     /locus_tag="VXE87_000593"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0842183.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(32204..32839)
                     /locus_tag="VXE87_000594"
     CDS             complement(32204..32839)
                     /locus_tag="VXE87_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0842184.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQIDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            32895..34193
                     /locus_tag="VXE87_000595"
     CDS             32895..34193
                     /locus_tag="VXE87_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0842185.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     SIILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKATKEIQMMNKEAGL"
     gene            34190..34852
                     /locus_tag="VXE87_000596"
     CDS             34190..34852
                     /locus_tag="VXE87_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0842186.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            34932..35480
                     /gene="raiA"
                     /locus_tag="VXE87_000597"
     CDS             34932..35480
                     /gene="raiA"
                     /locus_tag="VXE87_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0842187.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            35616..37589
                     /locus_tag="VXE87_000598"
     CDS             35616..37589
                     /locus_tag="VXE87_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0842188.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDETSESDISQINSFVANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            37586..38038
                     /gene="rplI"
                     /locus_tag="VXE87_000599"
     CDS             37586..38038
                     /gene="rplI"
                     /locus_tag="VXE87_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0842189.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            38082..39434
                     /gene="dnaB"
                     /locus_tag="VXE87_000600"
     CDS             38082..39434
                     /gene="dnaB"
                     /locus_tag="VXE87_000600"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0842190.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            39436..39702
                     /locus_tag="VXE87_000601"
     CDS             39436..39702
                     /locus_tag="VXE87_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842191.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            39791..41137
                     /gene="cbpD"
                     /locus_tag="VXE87_000602"
     CDS             39791..41137
                     /gene="cbpD"
                     /locus_tag="VXE87_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0842192.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      41220..41322
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            41393..41683
                     /locus_tag="VXE87_000603"
     CDS             41393..41683
                     /locus_tag="VXE87_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0842193.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            41646..42404
                     /locus_tag="VXE87_000604"
     CDS             41646..42404
                     /locus_tag="VXE87_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842194.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            42443..43450
                     /locus_tag="VXE87_000605"
     CDS             42443..43450
                     /locus_tag="VXE87_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0842195.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            43450..44178
                     /locus_tag="VXE87_000606"
     CDS             43450..44178
                     /locus_tag="VXE87_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842196.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            44297..44755
                     /locus_tag="VXE87_000607"
     CDS             44297..44755
                     /locus_tag="VXE87_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0842197.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            44757..47189
                     /locus_tag="VXE87_000608"
     CDS             44757..47189
                     /locus_tag="VXE87_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0842198.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSILKI
                     GVKAGQLKFDIA"
     gene            47510..48163
                     /gene="rr06"
                     /locus_tag="VXE87_000609"
     CDS             47510..48163
                     /gene="rr06"
                     /locus_tag="VXE87_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0842199.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            48160..49491
                     /gene="hk06"
                     /locus_tag="VXE87_000610"
     CDS             48160..49491
                     /gene="hk06"
                     /locus_tag="VXE87_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0842200.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            49586..50113
                     /locus_tag="VXE87_000611"
     CDS             49586..50113
                     /locus_tag="VXE87_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0842201.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            50192..>51936
                     /gene="pspC"
                     /locus_tag="VXE87_000612"
     CDS             50192..>51936
                     /gene="pspC"
                     /locus_tag="VXE87_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV0842202.1"
                     /translation="MFASKNERKVHYSIRKFSIGVASVAVASLFMGSVVHATEKEVTT
                     QVATSSNKANKSQTEHMKAAKQVDEYIKKKLQLDRRKHTQNVGLLTKLGVIKTEYLHG
                     LSVSKKKSEAELPSEIKAKLDAAFEQFKKDTLPTEPGKKVAEAEKKVEEAKKKAEDQK
                     EKDLRNYPTNTYKTLELDIAESDVEVKKAELELVKEEAKESRDEKKINQAKAKVENKK
                     AEATRLKNIKTDREKAEEAKRRADAKLQEANVATSEQDKSKRRAKREVLGELATPDKK
                     ENDAKSSDSSVGEETLTSPSLKPEKKVAEAEKKVEEAKKKAEDQKEEDRRNYPTNTYK
                     TLELEIAESDVEVKKAELELVKEEAKESRNEEKIKQVKAKVESKKAEATRLENIKTDR
                     KKAEEEEAKRRAAEEDKVKEKPAEQPQPAPAPQPEKPTEEPENPAPAPAPKPENPAEK
                     PKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAQPSTPKTGWKQENGMWYFYN
                     TDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYY
                     LNANGSMATGWLQYNG"
BASE COUNT        16477 a         8432 c        10915 g        16112 t
ORIGIN      
        1 tagtattaga aagataatag taataataga gtctgtgaaa tctgtggaaa acagccttta
       61 aacaagtcat atcaagtttt ttagcttgtt taaaaaatgt ggataaaaaa gataaaaaac
      121 taaaagttat ccacaaatta tttgattttc tttttgattg attcaatttc taaacgtaaa
      181 ttatcgtctt gatcaatcaa agattttatt ttggcatggg catgaatgac tgtggtatga
      241 tcttttcccc caaattcctt cccaattttt ggaagactat tatctgttag ttctctagat
      301 aaatacatgg ctacttgacg ggccaaaaca atattttgaa ggcgtctact tcccttcatt
      361 tctttgatac taacaccata aaagttacca acttcagttt ggattttatc aattgggatg
      421 acgagcattt ggctaacatc ttgtttgcgg gctctaatgg cttctgcagc aatatcaata
      481 gtgatatcct tgattttttt tactctggca attaaagtga tgtcgttgat ggctccctca
      541 agatctcgaa catttgaatc aaattgccca gctaggtatt ctagagtatc actttggaaa
      601 ttgtagccta aatgttccgt tttactttgt aaaatggcaa tacgtgtttc aaagtcaggg
      661 ggtgtgatag tttgtgtcaa tccccaacta aaacgcgtga caagcctctc ctcgagccct
      721 tctagatgtt ttggactacg atcactcgtt aggacaatct gtttttgctt gtcatgaagg
      781 gcgttaaagg tattgaaaaa ttcttcctga gttgcgactt tttttccgct gagtgactgg
      841 atatcatcga ttaacaaaag atcaagacta cgataggtct ttttaaactt ttccatttcc
      901 ccaagtctta ggtgatcaag aaagtcatta ataaagcttt cggcagggat atatttaaca
      961 cgcgcattag gaatattttt tagaatttca tttccaatag cgtttaataa gtgagtctta
     1021 ccaaggcctg gtcctccata gataaaaaga gggttatagg tcagagccaa atcttcagag
     1081 acagctaaag cggctgacac agcccaaaca tttccatccc cttgaataaa gttatcaaag
     1141 gtatactttt cttttaatcc cgtatctgaa taaggaatag atactaactt tggactatag
     1201 ttataaagag ttaaatttgt agcttcttca acttgtgagc tagtcgtatc ttgaggtttg
     1261 gtgaaaatat agtggggagt tatttcagcg tcataaattt caaaaccagc tactacaata
     1321 atatctttta gttgtttttc ccagaccatt tccatttcag agcgaggtag aaatatagtg
     1381 gcaacatttt cctctacctt gatgagttca gcttgaatag catagaaatc atacatggat
     1441 cgagtcagtc tttcttgtgc aaattctaat atacgattcc aaaattgttt ttctttcaat
     1501 cctttctcct cctttactat ttaaaagttt aatactagag atattttacc atagatagca
     1561 agaattttcc acaagctgtg aaaaataatc cacaatgtta ccaaacttta tccacaggtt
     1621 ggggataaaa gaagaaatta ttgatttatt aagcttttta tcgaaaaaca tagtggataa
     1681 ccttgtgaga taaaaaaata aaagaacagc cttatttcag gctgttgata attctactat
     1741 attcttcttg atttgaaaaa gaaataatga tttttccact gtctttttta gatagtttaa
     1801 tttctacatc taatccgagt agttttctta actgtttttc ttcattttgt atgaaatgat
     1861 tagttttttg ctgtttcttt tgttttttct ctgtcagaag agcttctaat ttccttacag
     1921 aaatatcttc ttctataatc cgttgaaaga aatagtcttg ttgttcctta tttaacccaa
     1981 ctagggaacg cgcatgggct tgtgatagtt tgccattttc tacttctgaa agaatctgtt
     2041 ctggcaagga aagtaaacga atggagttgc tgatatatgg acgagacttg cccatcttat
     2101 ctgcaatttc agcatgggtg aatcctttct ctacgagaga ttcataggcg cgtgcttctt
     2161 ctattgggtt taaattttct ctctgtaaat tttcaataat ggactggacc atcatctctt
     2221 ggtctgaaat ctgtttaaca acagctggga tagaccgtag accagctaaa agtgaagccc
     2281 gatagcgtct ctctcctgca aggatttcat aaccaataac aggagattga cgaacaataa
     2341 tcggttgaat gaccccattt tctttgatag actgtgctag ttcatctagt ttttctctat
     2401 caaattcttt tcggggttga tagggatttt tttgtatatc tgtgatagaa atcatttcaa
     2461 atttttccat gattctacac taacacatct tttctcttat gtaaagcttt ctttacatag
     2521 atgtcaatta agattctaaa tcacctgaac tcttgttaag tttgatagag gtagtttctt
     2581 ctttcccgtt acgatagtag gttatcttaa tggtgtctcc gatagaatgg ttgtaaagag
     2641 cactttgtaa gtctgttgat gaagcaatct ctttgtcatc tacttttgta attacatcgt
     2701 atttttcaag gtgaccattg gcaggcatat tactttgtac cgaacgaaca actacaccag
     2761 atgtaacatt acttggaata ttgagtcttc tgatgtcgct tgtactcaca ttagataaat
     2821 taaccatctg gattcccaaa gctggacgcg tcacttttcc gtttttttct aactgttcaa
     2881 taatattgat agcatcattt gcaggaattg cgaaaccaag accttctaca gatgttcctc
     2941 catttgtagc aattttactt gaggtaattc cgataacctg cccttgaata ttgatcagtg
     3001 ggccgccaga gttacctggg ttaatagcag tatcagtttg gatggctttt gtagaaatag
     3061 cttgtccatc ttccgatttt aaggatacat ttctattgag actggatacg ataccttgag
     3121 tgacagtatt tgcatattca gaacctaacg ggctaccgat ggcaatagca gtttctccta
     3181 cagttaactt actagaatca ccaaactcag ctactgttgt cactttttct gaagagattt
     3241 ttacgacagc aatatcagag aaagtgtcag ctccgacaat ttctccaggt actttagtcc
     3301 catctgacaa tcgaatatct actttgctgg cgccatttat aacgtgattg ttggtgacga
     3361 tgtaagcttc tttatcattc tttttataaa taactccaga tccttcacta gagattcgct
     3421 gagaatctgt gtcagtatca tcattgccaa atacgctatt ttgtctgttt gccgaataag
     3481 taataacaga aacaacagca tcttttactt tgttaacagc ctgtgttgtt gaattttcgt
     3541 tcttataggc agtttgtgta atagtactat tgttgttaga gttgtttaca ctactttttt
     3601 gagttagttg agttattgaa aaactaccca aggctccact aaaaaagcta atgacgataa
     3661 cgactaataa ttgaaaccat tttttgtaaa atgtttttag atgtttcata tttgcctcca
     3721 tatgtttgaa ttactgaaag tataaactga ctagcttaat tataacttaa acacaaaagt
     3781 tttacacaaa ctgtggataa ctcttttgaa actgtgattt tcttaattga aatctatttt
     3841 ttattttgtg aataagatgt gaaaaaatag agaatatgtt agaatagagt catgaaaatt
     3901 aaagttgtaa cagttgggaa actgaaagaa aagtatttaa aagatggtat cgcagagtat
     3961 tcaaaacgaa tttctagatt tgctaagttt gaaatgattg agttatcaga tgaaaaaaca
     4021 ccagataagg ccagtgaatc agaaaatcaa aagattttag aaatagaagg tcagagaatt
     4081 ttatcaaaaa ttgctgaccg tgatttcgtt attgtgttag ccattgaagg gaaaactttc
     4141 ttctcagaag aatttagtaa gcagttagaa gaaacttcta taaaaggatt ttctactctt
     4201 acttttatta ttgggggaag tttaggattg tcatcatctg taaaaaatag agccaatctt
     4261 tctgtcagtt ttggtcgcct aaccttaccc catcagttaa tgagactagt tcttgttgaa
     4321 caaatctatc gcgcttttac gattcagcag ggattcccct accataaata gaaaattgac
     4381 ttttaattga atttttggta gaataattgt attaggtctc atagctcagc tggatagagc
     4441 attcgccttc taagcgaacg gtcgcaggtt cgaatcctgc tgggatcaat ataatagcaa
     4501 agctgggaat tttcccggct tttttcttaa aaaagtacac tttgggagaa aaaaatgaca
     4561 gttgagagaa ttttatctaa aacgaaattc cattttgtat aatggttttt gtaagttagc
     4621 ttacaagaaa aaacatttta ggagatttta ttatgaaaaa cacagttaaa ttggaacagt
     4681 ttgtagcttt gaaggaaaaa gacttacaaa agattaaagg tggggagatg aggttgtcaa
     4741 aattcttccg tgattttatt ttacaaagaa aaaagtaatg aaataagggg aaagagtaat
     4801 ggatttattt ggatttggga cggttattgt tcatttttta attattagtc acagttacca
     4861 ttttatttgt aaaggtcaaa taaatagaaa agaattattc gtttttggtg cttatacatt
     4921 actaacagaa atagtatttg attttccctt atatattcta tatttagatg ggttagggat
     4981 tgaaagattt ttatttcctt tgggattata ttcctatttt cgatggatga aacagtatga
     5041 gagggataga ggactattcc taagtttact actatctctt ttatatgaga gcactcataa
     5101 ctttctgtcc gtaactttct cctctataac aggagataat tttgttttac aatatcattt
     5161 cccattcttt ttcgttgtga cggtgttaac ctattttgtt acattaaaaa tcatttacta
     5221 tttccatttg gaactagcct attttgacga ggactacctt tatcctttct tgaaaaaagt
     5281 attttttgct ttactattgc tacatattgt atctttcgtt tcagatatgg taagtacgat
     5341 taaacatttg aatagttttg taagtatttt gtcatctatt gtctttatct ctctcctttt
     5401 gaccttcttt gcaatgaatt ctcataaagt tcaaatggag aaagagattg ctttgaagca
     5461 gaagaaattt gaacagaaac atttacagaa ttacacagat gaaattgttg gtctgtataa
     5521 tgaaatccgt ggttttcgac atgattatgc tggaatgctt gtcagcatgc agatggcaat
     5581 tgacagtggt aatttacagg aaattgacag aatttacaat gaagttttag tcaaagcaaa
     5641 tcataaattg cgttcagata agtacactta ctttgatttg aacaacatag aagactcagc
     5701 tttacgaagt ttggttgctc agtcaattgt ctatgctcga aataatggtg tagagtttac
     5761 actggaagta aaagatacga ttaccaagct tccaattgaa ctattggatt tggttcgtat
     5821 catgagcgtt ttattgaata atgctgtcga aggatcggct gatagctata aaaagcagat
     5881 ggaagtagca gttattaaga tggaaactga aacagttatt gtgattcaga attcatgtaa
     5941 aatgacgatg actccttcag gagatctatt tgccttagga ttctccacta agggaagaaa
     6001 tcgcggagtc ggattaaata atgtgaaaga actactagat aagtacaaca atattatttt
     6061 agaaacagag atggaaggca gtacatttag acaaatcatt agatttaaga gggaatttga
     6121 atgaaagttt taattttaga agatgttatt gaacatcaag tgagactaga gagaatattg
     6181 gatgaaattt cgaaagaatc gaatattcca atatcataca agacaacggg aaaagtccgt
     6241 gaatttgaag aatacattga aaatgatgaa gtaaatcagc tttatttcct agatatcgat
     6301 attcatggaa ttgagaaaaa gggatttgaa gtggctcagc tcattcgtca ttacaatcct
     6361 tacgctatta tcgtctttat cactagtcga tcagagtttg cgactctaac ctataaatac
     6421 caggtatcag ccctagattt tgttgataag gatatcaatg atgagatgtt taagaagaga
     6481 attgagcaaa atatcttcta cacgaagagt atgttacttg aaaatgaaga tgttgtagat
     6541 tatttcgact acaattacaa aggaaatgat ttaaaaattc cttaccatga tattttgtat
     6601 attgaaacaa caggggtctc tcataaattg cgcattattg gtaagaattt tgcaaaagag
     6661 ttttatggta ccatgacaga tattcaggaa aaggacaaac atactcagcg attttattct
     6721 cctcacaagt catttttggt aaatataggc aatatcagag aaattgatcg aaaaaactta
     6781 gaaattgttt tctatgaaga ccatcgttgt cctatttcaa gattaaaaat tagaaaatta
     6841 aaagatattt tagagaaaaa atctcaaaag tgattgacaa ttagcaagaa attgatataa
     6901 tggttatatc tgctacagat agaaggtccg ttggtcaagg ggttaagaca ccgccttttc
     6961 acggcggtaa cacgggttcg aatcccgtac ggactatttt atccgccata gctcagttgg
     7021 tagtagcgca tgactgttaa tcatgatgtc gtaggttcga gtcctactgg cggagtatag
     7081 ataaaaggga acacagctgt gttcctcttt ttgtatcaat ttgtatcacc aagcattttc
     7141 ataaggaagt ctgttatttc ttgagaactt tctttttttc catgtgcaat ccaagtttgg
     7201 cagacaccaa aaagtgcatg agttagatag atgctactat attctaattc ggtggtattt
     7261 agattcagtt gcataaatcg cttttgtaaa tctgtactaa gcatgatatg aagtttattt
     7321 cgtaagaaat tttggatttc tttagtccca ttttcagaaa gaagggcagc cagaagtggt
     7381 tctgactcta gatattcaaa aacttctaaa atagcgtctc ttttgtgatg agcatgtttt
     7441 tgaaaaatat attcaaatgt atggaatagc ttgctttgat agtgctcaat catatcatac
     7501 ttatccttat agtgagtata gaagctggaa cgactaattc cggctttttc tactaatttg
     7561 acagtagaaa ttttatcaaa tggctgttcc atcagtaatt gtaccatagc attttcaata
     7621 gttcgctttg tttttaagcg tttgttactt tcttgcatat ttcctccttg taaacaaatt
     7681 agactatatg tctaaaaata gattttttat cttgtaattt agatttttta atgtataatc
     7741 tattatatca aaattttaga caatatgttt aaaaaaggag aaactaagtt taaagaatgg
     7801 aaagcaattt aaaaaaaacc aacctttatt attgtcatga tcgggatttc tcttattcca
     7861 gatctgtaca atatcatatt tttgtcatca atgtgggatc catatgggca attgtctgac
     7921 ttacctgtgg cagttgtaaa taatgataaa gaggcttcct ataatggtaa tactatggca
     7981 ataggaaaag acatggtgtc caatttaaaa gaaaataaaa ccttggattt tcattttgta
     8041 gatgaagagg aaggaaagaa gggattggaa gatggcgatt actatatggt agtgacttta
     8101 ccaagtgatt tatctgaaaa aacaactaca ttatccaata ttcaatcgac agcagcttat
     8161 caatcattga caagtgagca acaaactgag ataagtgatt ctgtatctca aaattcaact
     8221 gatagtattc aatcggctca gtcaattgta gctttagtac aagatttaca gggaagttta
     8281 gaaaacttac aaaatcaatc ttctaatctt tcgactttaa aaaatcaatc taatcaagta
     8341 tcacctatta cttctacttc tttgatagga ttgtcaagtg gattaacaga gatacaagga
     8401 gatgttacta gcaaattagt tcctgccagt cagtcgattg catcaggtgt aaacgcatat
     8461 actacaggtg ttgataaagt ttctcagggc gcaagtcaac taagtgaaaa aaatgccacc
     8521 ttgacaggta gtttgaataa actagtttca ggctcaaaca ccttgacaca aaaatcttct
     8581 agattgacag caggagttgg ttaattacaa tcaggatctg ggtaattagc agacaaatcc
     8641 agtcagttac tttcaggtgc ttctccatta gagaatagag ctaataaatt ggcagatgga
     8701 tctgggaaac tagcagaagg tggaacaaag ttaacttctg gattggaaga tttacagaca
     8761 ggacttgctt ctttaggaca aggactaggt aatgctagtg atcaactcaa atcagtatca
     8821 acagaatcta aaaatgcaga gattttgtca aatccactca atctttcaaa aacagacaat
     8881 gatcaagttc ttgtaaatgg aatcgcaata gctccttata tgatatcagt tgctcttttt
     8941 gttgcagcaa tatcaacaaa tatgatattt gcgaaattgc cttcaggacg tcatccagag
     9001 agccgttggg cttggttgaa atctcgagct gaaataaatg gtattatagc tgttttggca
     9061 ggaattttgg tatatggagg agttcagctt attggtttaa ctgctaatca tgagatgaga
     9121 atatttattc tcatcatcct aacaagttta gtattcatgt ctatggtgac cactttaaca
     9181 acgtggaata gccgtatagg agcttttttc tcacttattt tgcttttact acagttagca
     9241 tcaagtgcag gtacttatcc acttgctttg acaaatgatt tctttagatc tattaatccc
     9301 tggttaccaa tgagctattc agtttcggga ttacgacaaa caatctccat caacaagtca
     9361 ttttcctagc tgtcatacta gctctattta ctggtttagg tatgctagcc tatcaacata
     9421 agaaaataga agaagattaa aaaaatcgac cgattaactg gtcgattttt tatgccttag
     9481 atgactttcg tctgtgatta tagattccaa atagtaagag agaagtaaag gaacagattg
     9541 ctccagtaat aaaaccattg ggaatgaagg aaagtgtaat agttcctttc cccttgggaa
     9601 tgtcaacttt cataaatcca gtttgagctt gtttaatttc tattttctta ccatcttggt
     9661 aggcagacca acctttgtca taaggaatgg tgaagaaaat agatgtatct tgttggacat
     9721 catatgtagc aaaaaccttg tttttagaag ttgatactgt gacaggttgt tctttaattt
     9781 tttgaattgc ctcggtgaaa gttttggtat ctaaacgata gaaggtagga gattcaaatg
     9841 atacttgtga atttccaggg aaactaacat tgatattgaa agtttttttc tctttagtat
     9901 atcctagatt aaagaaggag aagacattat cagttgtaaa agtctttttt tcaccattta
     9961 caaggatgtc aaccttcttt tgtttatcgt tagaaaagtg aaggtttatg aaagagagat
    10021 aaacttggct gttttctgga acttcaattt gatactggat tgctgcatct tcatttgaag
    10081 aacttgtgac actaatcaaa tcattagtat tttctatttt ttctgttttt tcataaggta
    10141 ttggagaaaa ataatcaaaa ttgacgttag caagttgatt taaaaatgag gcctgattat
    10201 ccaaggtatg ttcattgaac ttgacatcat tgtaaacaga ttgactagca actgcaatcg
    10261 gaagagagta ttgattttca tatagggtaa gattatcttt ttgatagata tctttaaagc
    10321 catacttatc aataggactg tctgagatat tgtactggat accaaataaa ctatcagcca
    10381 aaatactatt atttgcatat cggagattga gattagtccc agaggattta aaaccaagtt
    10441 tatctaaagt agagcttgat gaacgatttc gaacagatga aaattgagag attccattgt
    10501 agttgaattt catactgtca tttcctgtct gagtttgtag tttttcagta cgagtaaatt
    10561 gatttccaat atatgttgag aaagattcca tagctgggat atctcgacta taagcacttc
    10621 gagaagcaaa tccccattcc ttagcaattc cgtccatttg agatgaagca tttaaactca
    10681 tttcaaccag tataaataaa gagattagaa tggcaaatag attcacagat ataaactttt
    10741 tgataactgc aaggagtaaa agagaataga caaccaaaaa ttcaagagta agcagaatat
    10801 tcaaatctgt taaaaaagaa taatgcgatt ttagatagat ggtagctaaa aatcctgtta
    10861 ctacaagaaa aagcgaaact aaaaaattcc agactttaag ttctttcaga cgctttaaga
    10921 cttctgctgc tgtgtaaatt aacaaggtag agaaaatcca agcatagcga tgtaaaaaca
    10981 tgtttggagt atgcatgcct tgccaaaata agtcaagagc ttctatgtaa aagcttgcaa
    11041 ttagaaatgc aaagaatatt acatatatga gtttcacgtg aaacttaata gatttcagcg
    11101 taaaaaataa aatggtcaaa ataaagggaa atagtccaac aaaaatcatt gggatggccc
    11161 catactttgt tgtgtcaaag gaaccaatga attgcttagc aaagagatca agataccagc
    11221 tactttcagt ttgaaacttt gtaacttcag tcaatttttc cccatgtgtc tgtaaatcaa
    11281 atagagtggg aatagtcata atcaaactag ccataccagc taaaaaggag ataactatga
    11341 aatcaagaac agatgatttt cgagtcttaa agtcccacga aatttgacag agataccaga
    11401 aaataagaaa caatactgtc atatatccaa aataataatt ttgaataaat aagattgaca
    11461 gacttgtaaa gtacaatagg agtttctttt cagttatcag tagatgtaaa ccagttataa
    11521 ttaaaggaat caagataaaa acatctagcc aggtttttat ctctaattga ctgacagtga
    11581 aactcatcag agcataggaa gtagataagg ctagttttaa agtctgaggg atagattgaa
    11641 acaatttatt caaactaaaa aaggttgaca gaccaatcaa tccaaatttt aagagagtgg
    11701 tcagatagac agcatctggc atattcgtta gatcaaaaaa gtaaactaga ggcgcgagaa
    11761 aactacccaa gtaataacta gatagggcat agaagtttag ccctagacca cttgtaaagg
    11821 tgtaaaacag actactattt ccatgtagga tatttcgtaa ggctacatca aaaataacgt
    11881 attgatgaaa gccatctcct aatagaggag agttgtcgct attccagtag ataccttgag
    11941 atagatatac tccagacata atcactacag gaatgatgaa agaaataaaa taggttcgat
    12001 atgtttttaa aaatgatttc atgttacctc gtagaatgat agaaaactca gttggttaac
    12061 ccaactgagt tttgaagttt tatttagtct ttccaaagtt ctttaacttt tgcttgtact
    12121 tctgcatttt ctaggaattc atcgtaggtt tcatcgatac ggtcaatgac gccattttta
    12181 gataagacaa tgatatggtt agccaaagtt tgaataaact cgtggtcatg gctggcaaag
    12241 atgattgatt ctttaaagtt tttcaatcca tcattcaagc ttgagataga ttccaagtcc
    12301 aagtgatttg ttggatcatc aagtacaagg acatttgatt ttaagagcat gagttttgaa
    12361 agcatgacac gaactttttc tccccctgac aagacattta caggtttgtt aacttcatct
    12421 ccagagaaga gcatacggcc gaggaaacca cgtaggaaag tattgtcatc atcttcttta
    12481 cttgcgaatt gacgcaacca gtcaagaatt gattctcctc ctgcaaaatc agctgagtta
    12541 tcttttggta ggtaagattg actagttgta actccccact tgacagttcc ttcatagtca
    12601 atatctccca tgattgcacg aattaatgca gtcgtttgaa tatcattttg tccaataagt
    12661 gctgtcttat catctggacg caagatgaaa ctaatattat ccaagatagt ttcaccatca
    12721 atctttacag ttagattttc tactgtcaag agatcattac caatctcacg ttccgcttta
    12781 aagttgataa atggatattt acgactagat ggtacaatct cttctagctc aatcttatca
    12841 agcattttct tacgtgatgt tgcctgcctt gacttagaag cattggcaga gaaacgagca
    12901 acgaattctt gcaattgttt aattttttct tctgctttag cattacggtc tgctagcaat
    12961 ttagcagcaa gctcagaaga ttccttccag aagtcgtagt ttccgacata gagtttgatt
    13021 tttccaaagt caaggtcggc catgtgagta caaactttgt ttaagaagtg acggtcgtgg
    13081 gatactacga taactgtgtt atcaaagtca attaagaagt cttctaacca agtaatcgat
    13141 tggatatcca aaccgttagt aggctcgtcc aagagaagaa catctggttt accaaaaagt
    13201 gctttggcga ggagaacctt tactttttca ccgttggcca attcgctcat gttttggtag
    13261 tgtaattctt ctggaatgtt taggttttga agtagttgag aggcttcact ctctgcttcc
    13321 caacctccaa gttcggcaaa ctctccttcg agttcggcag cacgaacccc gtcctcgtct
    13381 gagaaatctt ccttcatgta gatagcatct ttctctttca tgatgctata aagtttttca
    13441 tttcccatga taacgacatc aatggcacgt tcatcttcgt agtcaaagtg attttgacga
    13501 agaacagaga gacgttcatc tggaccaaga gagatgtgac cagtagtagg ttcgatatct
    13561 ccagctaaaa tttttaaaaa ggttgatttt ccggcaccat tagcaccgat taatccgtaa
    13621 gtatttcctt ctgtaaattt gatattgaca tcatcaaaaa gtttgcgatc actaaaacgt
    13681 agtgaaacat cagatactgt aagcaatatt tttctcctat atgtgtaata tatttattct
    13741 actagaaaat acagaaatat tcaaattttt atttatcaat tttgtgtaaa ttatatttac
    13801 agtatccttt acacaaatct gtaaaaagca aggctgattt attttgataa attacggtta
    13861 tttcattaaa aaaatgctat aattgaaagg actatatcga aggagaacaa aatgactaaa
    13921 cccattattt taacaggaga ccgtccaaca ggaaaattgc atattggaca ttatgttgga
    13981 agtctcaaaa atcgagtatt attacaggaa gaggataagt atgatatgtt tgtgttcttg
    14041 gctgaccaac aagccttgac agatcatgcc aaagatcctc aaaccattgt agagtctatc
    14101 ggaaatgtgg ctttggatta tcttgcagtt ggattggatc caaataagtc aactattttt
    14161 attcaaagcc agattccaga gttggctgag ttgtctatgt attatatgaa tctagtttcg
    14221 ttagcacgtt tggagcgaaa tccaacagtc aagacagaga tttctcagaa aggatttgga
    14281 gaaagcattc cgacaggatt cttggtctat ccaatcgctc aagcagctga tatcacagct
    14341 ttcaaggcta attatgttcc tgttgggaca gatcagaaac caatgattga gcaaactcgt
    14401 gaaattgttc gttcttttaa caatgcatat aactgtgatg tcttggtaga gccggaaggt
    14461 atttatccag aaaatgagag agcagggcgt ttgcctggtt tagatggaaa tgctaaaatg
    14521 tctaaatcac taaataatgg tatttattta gctgatgatg cggatacttt gcgtaaaaaa
    14581 gtaatgagta tgtatacaga tccagatcat atccgcgttg aggatccagg taagattgag
    14641 ggaaatatgg ttttccatta tctagatgtt tttggtcgtc cagaagatgc tcaagaaatt
    14701 gctgatatga aagaacgtta tcaacgaggt ggtcttggtg atgtgaagac caagcgttat
    14761 ctacttgaaa tattagaacg tgaactgggt cctattcgtg agcgccgtat tgaatttact
    14821 aaggatatgg gagaagttta taatatgatt caaaaaggta gtgaaagagc gcgtgaagtt
    14881 gcgggtcaaa ccctatctga ggtaaaaggg gcaatgggac ttcattactt taactaagtt
    14941 tattttacaa gaaactatct tttctatctc gaagaaaaga tagtttttta tttacccctg
    15001 taacatttga caaattttta tagaatggta tgatagatac aatataaaaa gagtcaagct
    15061 caaaaagaaa gaaaagagga aacttcgaat gtctaattgg gacactaaat ttttgaaaaa
    15121 aggttttacc tttgatgatg tattgcttat tccagctgaa agtcatgtgt tgcctaacga
    15181 tgcagattta acaactaaat tggcagataa tttgacttta aatatcccaa ttattaccgc
    15241 tgccatggac acagttacag agagtcaaat ggccattgct attgctcgtg caggcggtct
    15301 cggagttatc cataaaaaca tgtcaattgc tcaacaagca gacgaggttc gtaaggtaaa
    15361 acgttctgaa aatggagtta ttattgatcc gttcttcttg acgcctgaac atacaattgc
    15421 tgaagcagat gagcttatgg gtcgttaccg catcagtggt gttccagttg ttgaaacact
    15481 tgaaaatcgt aaattggttg gtattttgac aaaccgagat cttcgtttta tttcagatta
    15541 taatcaacca atttcaaacc atatgactag tgaaaatctt gttactgctc ctgtgggtac
    15601 ggatcttgca acggctgaga gtattcttca agagcatcgt attgaaaaac ttccgttggt
    15661 cgatgaagaa ggcagtcttt ctggtttgat cactatcaaa gatattgaaa aagttattga
    15721 gtttccaaat gcggctaaag atgagtttgg tcgtcttcta gttgcaggtg cagtaggtgt
    15781 tacttcagat acatttgaac gtgcagaggc tctttttgag gcaggagcgg atgcgattgt
    15841 tattgatact gcacatggtc attctgcagg tgtcttgcgt aaaattgccg agattcgtgc
    15901 tcatttccca gatcggactt tgattgctgg aaatattgct actgctgaag gtgcacgtgc
    15961 cctttatgaa gcgggtgtag acgttgttaa ggttggtatt ggaccaggtt ctatctgtac
    16021 tactcgtgtg attgctggtg ttggtgttcc gcaagtaaca gctatctacg atgctgcagc
    16081 tgttgcgcgc gaatatggta aaacgattat tgctgacggt gggatcaagt attctggaga
    16141 tattgtaaaa gcacttgctg caggtggaaa tgctgttatg cttggatcta tgtttgctgg
    16201 aactgatgaa gctccaggcg aaactgaaat cttccaagga cgtaaattca agacttaccg
    16261 tggtatggga tcaattgctg ctatgaagaa aggttcaagc gaccgttatt tccaaggttc
    16321 tgtcaatgaa gcaaacaagc ttgttccaga aggaattgaa ggtcgtgttg cttataaagg
    16381 agcggcagct gatattgttt tccaaatgat tggtggtatt cgctctggta tgggttactg
    16441 tggtgcagct aaccttaaag aactacacga taatgctcaa tttattgaaa tgtctggtgc
    16501 tggtttgaaa gaaagccatc ctcatgatgt gcaaattact aatgaggcac caaattattc
    16561 tatgtaaaaa acaatgaaaa gaactccagt gaaaacagga gttcttttac aatgttgtca
    16621 atttctattt acagcagctt taccatcctg aatagtgaag atacttagat tttctggcag
    16681 attttgaaga tggtctaagc ttgttgttgt gataaaggtt tggattgatt gagaaatcgt
    16741 ttctaataat tttaactgtc tagtgttgtc aagttcactc atcacatcgt caagcagtaa
    16801 tatcggagat tctgtggtaa tgctttccat taattcgatt tctgctaatt ttatcgagag
    16861 gacgagacta cgatgttgac cttggcttcc gaaactagca tccatcccat ttatataaaa
    16921 agaaatgtca tctcgatgag gaccgacacc agtattcttt ttaaataaat ctctggatct
    16981 acttttttct aaagcaattt tgaaagattc ggataagttt tgtttgtcag ttatattgac
    17041 agaagattga taggatattg acaactcttc gatctgatta gagagttcaa aatgtttctt
    17101 acgcccaaat gattctagtt tttttatgaa atctaagcgg tgattcatta cacgacatcc
    17161 ataatcaact agctgatcat ctaacacaga aaggaatgtt tcatctattt tttgagctga
    17221 ttttaggtaa gtgtttcttt gctttaggat gtggttataa ttggttaagt cagataaata
    17281 gattggctta atttgcccaa gttccatatc aatgaatttt cgtcgaatcg aaggtgctcc
    17341 tttaattagt tgtaaatctt caggagcaaa taagacaaca ttcatgtgtc ctacataatc
    17401 tgaaaggcgt gcctgtttta agtgattaac ttttgttaca cggccttttt gtgttagttc
    17461 gatttctagg ggaatggatc cagttttttt ctgaacgaga cctgaaagat gaagttgttc
    17521 ctcatcaaaa tgaatgagat ttttatctgt tcgagttcga tgactacgcg ttaaggctaa
    17581 aaaatagata gcctctaaca tgtttgtttt tccttgtgca ttacgtccca aaaagacatt
    17641 caatttagga ttaaagtcta ttttcgtttc tttgtaatta cgaaaagtct tgagagatag
    17701 atgttgtagc cacatgatta tctaccaggg aatcgtggag cttgttggct tttaggtgat
    17761 gaagcaggtt tcgatttgtc ttttttaact cccttattca tctttttgac aagtttagcg
    17821 atccgttctt tttcaacttt atcagcttgg tattcatctt gttcttcaga agtaggttgt
    17881 gtcaacaaga tgtcaatgtt catgtcaggg atgtcaactt tatcgccaat acgaagtttt
    17941 tttccacgac aactctctaa ttccctatta aagtaaacag aatgttcaga gagaaatgat
    18001 ttaatagctc ctccgctatg tgtaattcca agttctttga gtagtgcttg gagggtaata
    18061 aattcttcaa ataatttgta ttccataatt cacctcaatc tttggtatta taccatattt
    18121 tcctaaaaat agtgagagag acagcgagaa atgtaagcga tttttatttc aaaagtgtta
    18181 cagggaacaa gaaaatttca ggttttcgtg atataataga agtctgtata taaggaggta
    18241 aatcatggag ttagtgcatg gaatttcaac acattttatc caatcaaaaa agtttaaaac
    18301 aaacaaaatt accgtgcgtt ttaccgctcc attatccctt gatacgattg caggtcacat
    18361 gttgagtgca agtatgctag agactgctaa tcagatgtac cccacttctc aagatttgag
    18421 gagacacttg gccagtctat acggtacaga tatgtcaacc aattgtttca gaagagggca
    18481 aagccacatt atagaattga catttaccta tgttcgtgat gagtttttaa gtaggaaaaa
    18541 cgtgctaacc tctcagattt tggaacttgt aaaagaaact cttttttcac ccgtagtagt
    18601 tgataatggg tttgatccgg ccttatttga aattgagaaa aaacaattgc tagcaagttt
    18661 agcagctgat atggatgatt ctttttattt tgcacataaa gaattggata aattgttttt
    18721 tcatgatgaa cgtcttcaat tggaatatag tgatttacga aatcgtattt tagctgaaac
    18781 tccacaaagt tcttattctt gtttccaaga atttttagcc aatgatcgaa tagatttctt
    18841 tttcctaggt gattttaatg aggttgaaat tcaaaatgta ttagaatcat ttggctttaa
    18901 aggtcgaaaa ggagatgtga aggttcagta ttgtcaacct tattctaata tccttcagga
    18961 aggtatggtt cggaaaaatg tgggacaatc cattttggaa ttaggttatc attaccgttc
    19021 taaatatggt gatgagcaac atttacccat gattgtaatg aatggtttac ttggtggatt
    19081 tgctcactct aagctcttta caaatgtccg tgaaaatgct ggattagctt ataccatttc
    19141 aagtgagctt gatttattta gtgaattctt gaggatgtat gctggtatca atcgagaaaa
    19201 tcgtaaccag gctcgtaaaa tgatgaataa tcaactgctt gatttaaaaa aaggttattt
    19261 tacagagttt gagttaaatc agaccaagga aatgattcgt tggtcgttgt tactttctca
    19321 agataatcaa tcttcattga ttgaacgtgc ttatcaaaat gccttatttg gaatatcttc
    19381 agcagacttt aaaggttgga ttgcaaaact cgagcaagtt gacaaagatg ctatttgtag
    19441 agcagctaat aatgtgaaac tacaagcgat ttactttatg gaaggaatag aatgacaaag
    19501 gttgtttttg aagaaaaata ctatccagct gtaaaagaaa aggtttatcg aactcgtttg
    19561 gccaatggat tgacagttgc tcttttgcct aaaaaggaat ttaaagaggt ttacgggagt
    19621 gtcactgtac agtttggttc ggtagatacg tttgtcacag aagttgacgg agatgtaaaa
    19681 caatatcctg gaggaattgc tcattttctt gaacataaat tatttgagag agaagattct
    19741 agtgatttga tgtcggcttt tacgagtcta ggtgcagata gtaatgcctt tacaagcttt
    19801 acaaaaacaa actatctttt ttcagcaacg gattattttt tagaaaattt agatttactt
    19861 gatgaattgg taacatcagc acactttact gaagcttcca ttctgacaga gcaggatatt
    19921 attcagcaag aacgagaaat gtaccaagat gatccagatt cgtgtttatt cttttcaact
    19981 ttagcgaatt tgtatcctgg tacaccttta gcaactgata tagttggaag tgaggagtcc
    20041 atttcccaaa tcaatctaac taatttgcaa gaaaatttta caaagtttta caaacctgta
    20101 aacatgtctc tgtttttagt tggtaatttt gatgtggagc gagtacagga ctattttgaa
    20161 agcaaagaac tgaaagattc agattttcag gaagtagcaa gagaaaagtt gtttttacag
    20221 cctgtaaagc caacagatag tatgagaatg gaagtatctt ctcccaaact agcgattgga
    20281 gttagaggta agcgagaagt ttctgaagcg gattgctatc gacatcatat tttattaaaa
    20341 ttattgtttg caatgatgtt tggttggact tcggatcgtt ttcaaaaatg ttatgaatca
    20401 ggtaaaattg atgcatcctt atctctggaa gttgaagtaa caagtcgctt tcattttgtc
    20461 atgttgacaa tggatacgaa agagccagtt gctttgtctc atcaatttag gaaggctatt
    20521 cgtaatttta caaaggattt agatattaca gaggaacatt tagatattat caaaagagag
    20581 atgtttggcg aatttttcag tagcatgaac tctcttgaat ttattgcaac gcaatatgat
    20641 gcttttgaaa atggtgagac aatttttgat ttgccgaaaa ttttacagga aattacttta
    20701 gaggatgtcc ttgatgctgg acatcattta atagatgatg gtgacatagt tgattttaca
    20761 atattcccat cgtagtaacc tattataata gacactagaa agaagggatg acaagtatga
    20821 gaaaaaaaac aattggagag gttttacgat tagctagaat caatcaggga ttgagtttag
    20881 atgaattgca gaaaaagaca gaaatccagt tagatatgtt ggaagcaatg gaagcagacg
    20941 atttcgatca acttccaagt cctttttaca cgcgttcttt cttgaaaaaa tatgcatggg
    21001 ctgttgagtt agatgaccaa attgttttgg atgcttatga ttctgggagt atgattactt
    21061 atgaggaagt agatgttgat gaagatgagt tgacaggtcg tagacgttca agtaagaaaa
    21121 agaagaaaaa aacatcattt ttacctttat tttattttat cctttttgct ttatcgattt
    21181 taatttttgt gacttattat gtttggaact atattcaaac tcaaccagag gagccttctc
    21241 tttctaatta cagtgtggtt caatcaacaa gttcaactag ctctgttccc cactcctcaa
    21301 gtagtagttc ttctagtata gaatcagcta taagtgtatc aggcgaagga aatcatgtag
    21361 aaatcgctta taagacaagt aaggaaacag ttaaattgca attggcagtt tcagatgtta
    21421 caagttgggt cagtgtttca gaaagcgaac ttgagggcgg tgtaacctta tcgccaaaga
    21481 agaaaagtgc agaagcaaca gttgcaacta aaagtcctgt aacaattacg ttaggtgttg
    21541 taaaaggtgt tgatttgaca gtagataatc agactgttga tttatcgaaa ttaacagctc
    21601 agactggaca aatcactgta acctttacta aaaattaagg aaaaacgaat gaaaaaagaa
    21661 caaattccca atctcttaac aataggtcga attctcttta tacctatttt tatctttatt
    21721 ttaacgatag gaaattcgat agagagtcat atagttgcag ctattatctt tgctgttgcc
    21781 agtattaccg actatttaga tggatattta gctcgtaaat ggaatgtggt cagtaatttt
    21841 ggtaaatttg cagatcctat ggcggataag ttactagtta tgtcggcttt tattatgttg
    21901 attgagttag gtatggctcc ggcttggatt gttgcagtga ttatctgtcg tgagttagct
    21961 gtgacaggtt taaggctttt attggttgaa actggtggaa caattttagc agcagcaatg
    22021 cctggaaaaa ttaaaacttt tagtcagatg tttgctatta ttttcttgct attacattgg
    22081 actttgcttg gtcaagttct actttatgta gccttatttt tcactatcta ctctggctat
    22141 gactatttca agggtagtgc ctatgtattt aaagggacat ttggttcgaa atgaaatcaa
    22201 taattgatgt aaaaaatctt tcttttcgct ataaagaaaa tcagaactac tacgatgtga
    22261 aggatattac gtttcacgtg aaacgtggag aatggctttc gattgtaggg cataatggta
    22321 gtggtaaatc aacgacggtt cgattaattg atggcttact ggaagcagaa tccggagaga
    22381 ttgtaattga tggccaacgt ttgactgagg aaaatgtttg gaatatacgt cgtcaaatcg
    22441 gtatggtttt tcaaaatcca gacaatcaat ttgttggagc gactgttgaa gatgatgttg
    22501 cttttggttt ggaaaatcag ggactttctc gtcaagaaat gaaaaagaga gtggaagaag
    22561 ctctggcttt agttggcatg ttggacttta aaaagagaga gccagcgcgt ctatcaggtg
    22621 gccaaaagca acgtgtggcc attgcaggtg ttgtagccct aagaccagct attttaatct
    22681 tagatgaagc aacgagtatg ttggatcctg aggggcgtag agaacttatt gggacagtaa
    22741 aaggaattcg aaaagactat gatatgacgg tcatttctat tacccatgat ttggaagaag
    22801 tcgccatgag tgatcgcgta ttggtcatga aaaaagggga aattgaatca actagtagtc
    22861 caggggagct tttctctcga aatgatttag atcaaattgg attagacgat ccttttgcta
    22921 atcaattaaa aaaatctttg agccagaatg gctatgattt acctgaaaat tatttgacag
    22981 aaagtgagct agaggataag ctatgggaat tgctctagaa aatgtgaatt ttacatatca
    23041 agaaggtact cccttagctt cagcagcttt gtcggatgtt tctttgacga ttgaagatgg
    23101 ctcttataca gctttaattg ggcacacagg tagtggtaaa tcaactattt tacaactctt
    23161 aaatggttta ttggtgccaa gtcaagggag tgtgagggtt tttgatacct taatcacctc
    23221 gacttctaaa aataaagata ttcgtcaaat tagaaaacag gttggcttgg tatttcagtt
    23281 tgctgaaaat cagatttttg aagaaacggt tttgaaggac gttgcttttg gaccgcaaaa
    23341 ttttggagtt tctgaagaag atgctgtgaa gactgcgcgt gagaaactgg ctctggttgg
    23401 aattgatgaa tcactttttg atcgtagtcc gtttgagctg tcagggggac aaatgagacg
    23461 tgttgccatt gcaggcatac ttgccatgga gccagctata ttagtcttag atgagccaac
    23521 agctggtcta gatcctctag ggagaaaaga gttgatgacc ctgttcaaaa aactccacca
    23581 gtcagggatg accatcgtct tggtaacgca tttgatggat gatgttgctg aatatgcaaa
    23641 tcaagtctat gtaatggaaa agggacgttt agtaaagggg ggcaaaccaa gtgatgtctt
    23701 tcaagacgtt gtttttatgg aagaagttca gttgggagta cctaaaatta cggccttttg
    23761 taaacgattg gctgatagag gcgtgtcatt taaacgatta ccgattaaga tagaggagtt
    23821 taaggagtcg ctaaatggat agtatgattt tggggcgtta tatcccaggg gattcgattg
    23881 ttcaccgatt ggatccacgt agcaaattgc ttgctatgat gctactgatt ttgattgtgt
    23941 tttgggctaa taaccccttg acgaatctga ttctttttat agcgacaggg atatttattg
    24001 ccttgtcagg agtatctctt tcatttttta ttcagggctt gaagtctatg tttttcttga
    24061 ttgccttcac aactattttt caactatttt tcatttctaa tgggaatgtt ttatttgagt
    24121 tttcgtttgt gagaatcacg gattatgctt tgcaacaagc tgggattatt ttttgtcgct
    24181 ttgtattgat tattttcttt tcaactttgt taaccttaac aaccatgcct ttaagtttgg
    24241 catcagctgt cgaagcttta ttagcacctt taaagcgtgt gaaagttcca gttcatgaaa
    24301 ttggattgat gctgtctatg agtttgcgtt ttgtcccaac cttgatggat gatacgacgc
    24361 ggattatgaa tgcacagaaa gctcgtggag tggattttgg agaaggaagt atcgttcaaa
    24421 aagtaaaggc gatgattccc attttgattc ctctttttgc gacaagttta aaacgtgcag
    24481 attccttggc tatcgctatg gaagcgcgtg gctatcaggg tggaaaaggc agaagtcaat
    24541 accgacaatt gaaatggact ctaaaggata cgctgaccat tcttgttatt ctcgtacttg
    24601 gttgttgttt atttttctta aaatcttagt agctttcagg aattgataaa aagttactgt
    24661 aacagttttt gatataaagg tagggatatg aaccgtttta aaaaatcaaa atatgtcatt
    24721 attgtttttg tcactgttct gcttgtgtca gctctcttag cgacgactta ttcaagtaca
    24781 attgtgacaa aattaggaga tggaatctca ttggttgata gagttgtaca aaaacctttt
    24841 cagtggtttg attctgtcaa atcagatttg gctcatttga cacgaacata taatgaaaat
    24901 gaaagtttga agaaacagct ttaccaatta gaagttaaat caaatgaggt ggaaagttta
    24961 aagacagaaa atgaacaact gcgccaattg cttgatatga agtctaaatt gcaagccaca
    25021 aagactttag cagcagatgt tattatgcgt tctccggtat cttggaagca ggagttgacc
    25081 ttagatgcag gtagatcaaa aggtgcttct gagaacatgt tagctattgc aaatggtggc
    25141 ttgattggga gtgtttcaaa agtagaggag aactctacta tagtcaacct tctgacaaat
    25201 acggaaaatg ctgataagat ttctgttaaa attcaacatg gctctactac aatttatgga
    25261 attattattg gctatgacaa ggaaaatgac gttcttaaaa ttagccaatt aaatagtaat
    25321 agtgatatta gtgcgggaga taaggtgact actggtggat taggaaactt taacgttgct
    25381 gatattcctg ttggtgaagt ggttgccaca acgcatagta cagactattt gacacgagaa
    25441 gtaactgtta aattgagtgc agatactcat aatgtagatg tgatagaatt agtggggaat
    25501 tcataatgag acagttgaag cgagttggag tatttttatt gcttcctttc tttgttctaa
    25561 ttgacgccca tattagccag cttctgggct catttttccc ccatgtacat ttggctagtc
    25621 attttctttt tctatttctc ttatttgaga cgatagaagt atcagagtat ctctacctag
    25681 tctattgttt tgttataggc ttggtttatg atgtttactt tttccatcta atagggatta
    25741 caactctctt atttatctta ttgggagcct tccttcataa attgaatagt gttattttgt
    25801 tgaatcgttg gacaagaatg ctagctatga ttgtgctgac attcctgttt gaaatgggta
    25861 gttatctttt ggcttttatg gtagggttga cagtagatag catgtcgatt tttatagtct
    25921 atagcttggt accgacgatg attttaaatt ttttatggat tactgttttt caatttattt
    25981 ttgaaaaata ttatctataa gaacgacata taaatgtaac aaaggcgtaa tatttattag
    26041 gccttttttt ggtatactag tattgtcttt aaaagaagga gtatctacgt aatatgaaga
    26101 aaaaaatctt agcgtcactt ttattaagta cagtaatggt ttctcaagta gctgttttaa
    26161 caactgcgca tgcagaaacg actgatgaca aaattgctgc tcaagataat aaaattagta
    26221 acttaacagc acaacaacaa gaagcccaaa aacaagttga ccaaattcag gagcaagtat
    26281 cagctattca agctgagcag tctaacttgc aagctgaaaa tgatagatta caagcagaat
    26341 ctaagaaact cgagggtgag attacagaac tttctaaaaa cattgtttct cgtaaccaat
    26401 cgttggaaaa acaagctcgt agtgctcaaa caaatggagc cgtaactagc tatatcaata
    26461 ccattgtaaa ctcaaaatca attacagaag ctatttcacg tgttgctgca atgagtgaaa
    26521 tcgtatctgc aaacaacaaa atgttagaac aacaaaaggc agataaaaaa gctatttctg
    26581 aaaaacaagt agcaaataat gatgctatca atactgtaat tgctaatcaa caaaaattgg
    26641 ctgatgatgc tcaagcattg actacgaaac aggcagaact aaaagctgct gaattaagtc
    26701 ttgctgctga gaaagcgaca gctgaagggg aaaaagcaag tctattagag caaaaagcag
    26761 cagctgaggc agaggctcgt gcagctgcgg tagcagaagc agcttataaa gaaaaacgag
    26821 ctagccaaca acaatcagta cttgcttcag caaacactaa cttaacagct caagtgcaag
    26881 cagtatctga atctgcagca gcacctgtcc gtgcaaaagt tcgtccaaca tacagtacaa
    26941 atgcttcaag ttatccaatt ggagaatgta catggggagt aaaaacattg gcaccttggg
    27001 ctggagacta ctggggtaat ggagcacagt gggctacaag tgcagcagca gcaggtttcc
    27061 gtacaggttc aacacctcaa gttggagcaa ttgcatgttg gaatgatggt ggatatggtc
    27121 acgtagcggt tgttacagct gttgaatcaa caacacgtat ccaagtatca gaatcaaatt
    27181 atgcaggtaa tcgtacaatt ggaaatcacc gtggatggtt caatccaaca acaacttctg
    27241 aaggttttgt tacatatatt tatgcagatt aatttacaga gggactcgaa tagagccctc
    27301 ttttcaggtt ttaccgtgac aatctctatt aaaaattata tcaaaatagc ttgaaaatat
    27361 tggaaaagta tggtagaatg aaaattgtcg tgtgaacgat aatactcatt cttgatgaat
    27421 tgtgaagcag ttgcccttgg gtcgttttgc gagttgaagt caagaagagg aaaaaaacaa
    27481 aaaggagaaa tactcatggc agtaatttca atgaaacaac ttcttgaggc tggtgtacac
    27541 tttggtcacc aaactcgtcg ctggaatcct aagatggcta agtacatctt tactgaacgt
    27601 aacggaatcc acgttatcga cttgcaacaa actgtaaaat acgctgacca agcatacgac
    27661 ttcatgcgtg atgcagcagc taacgatgca gttgtattgt tcgttggtac taagaaacaa
    27721 gcagctgatg cagttgctga agaagcagta cgttcaggtc aatacttcat caaccaccgt
    27781 tggttgggtg gaactcttac aaactgggga acaatccaaa aacgtatcgc tcgtttgaaa
    27841 gaaattaaac gtatggaaga agatggaact ttcgaagttc ttcctaagaa agaagttgca
    27901 cttcttaata aacaacgtgc gcgtcttgaa aaattcttgg gcggtatcga agatatgcct
    27961 cgtatcccag atgtgatgta cgtagttgac ccacataaag agcaaatcgc tgttaaagaa
    28021 gctaaaaaat tgggaatccc agttgtagcg atggttgaca ccaatactga tccagatgat
    28081 atcgatgtaa tcatcccagc taacgatgac gctatccgtg ctgttaaatt gatcacagct
    28141 aaattggctg acgctattat cgaaggacgt caaggtgagg atgcagtagc agttgaggca
    28201 gaatttgcag cttcagaaac tcaagcagat tcaattgaag aaatcgttga agttgtagaa
    28261 ggtgacaacg cttaatttat acaaatagta attacctagg agggcggggc ttagcccggc
    28321 tctcctattt tcaaaaaata taggagaatt aaaatggcag aaattacagc taaacttgta
    28381 aaagagttgc gtgaaaaatc tggtgccggt gttatggacg ctaaaaaagc gcttgtagaa
    28441 acagacggtg acatcgaaaa agcgattgaa ttgcttcgtg aaaaaggtat ggctaaggca
    28501 gctaagaaag ctgaccgtgt tgctgcagaa ggtttgactg gtgtttatgt taacggtaat
    28561 gttgcagcag ttattgaagt aaacgctgaa actgacttcg ttgcaaaaaa cgctcaattc
    28621 gttgaattgg taaatactac agctaaagtc attgctgaag gaaaacctgc taacaacgaa
    28681 gaagctcttg ctttgataat gccttcaggt gaaactcttg aagctgcata cgtatctgca
    28741 acagcaacta taggagagaa aatctcattc cgtcgctttg cattgattga aaaaacagac
    28801 gcacaacact ttggagcata ccaacataac ggtggacgta tcggtgttat ttcagttgtt
    28861 gaagatggag acgaagcact tgctaaacaa ttgtcaatgc acatcgcagc gatgaaacca
    28921 acagttcttt cttacaaaga attggatgag caattcgtta aagatgagtt ggcacaattg
    28981 aatcacgtta tcgaccaaga caacgaaagc cgtgcaatgg ttaataaacc agctcttcca
    29041 cacttgaagt atggatcaaa agctcaatta actgatgatg ttattgctca agctgaagct
    29101 gacatcaaag ctgaattggc tgcagaaggc aaaccagaaa aaatctggga caaaattatt
    29161 ccaggtaaaa tggatcgctt catgcttgat aacactaaag ttgaccaagc ttacacactt
    29221 cttgcacaag tttacatcat ggatgacagc aagacagttg aagcatacct tgaatcagtt
    29281 aacgcttcgg tagttgagtt tgctcgcttt gaagttggtg aaggtatcga gaaagctgca
    29341 aacgacttcg aagctgaagt tgcagctaca atggcagcag ccttgaataa ctaataatag
    29401 aaaggaagca aattgcttcc ttttttgtat agggcttaga tttttcctga aattgttttt
    29461 tccccagtct cactcgatta gaataattaa aacaaaaagc cctataataa gggctaagtg
    29521 catttaggag actatactta aaattcatag taagcgcgtt cataacaagg tatctatcct
    29581 aattccccaa cttccagtat actagataaa aaataattat cggagtaaag gtattgtact
    29641 atgataattc aactaagtga tttaggtcaa gttcaccttg tttgtggcaa gacagatatg
    29701 aggtagggaa tagactcatt agcctatgta gttaaaaccc actttgaatt ggattctttc
    29761 tccggtcaag tctttctctt ttgtggtgaa cgtaaagacc gctttaaagc cctttactgg
    29821 gatggtcaag gattttggct actatataaa cgctttgaga acggaaaact gacttggcta
    29881 agtacagaaa aggatgtcaa agctctcgca cctgaacaag tagattggct tatgaagggc
    29941 ttttctatca ctccccaaat atagtggatt taaactagaa tagtacacct ctgcttctaa
    30001 aacattgtta gaaatcgatt tgactatcct gttcttattt cattttacta taaattcatc
    30061 agaaagtcgt gatttctatt gaaatgagga ctttcttttt atactcatct gttttcaaaa
    30121 agcattctag tccatctccg attaacgatg gactttatca cctccttctc cagtccttgt
    30181 atgacatctt ggagttgatt catgacatct tccaaagttc gaaaggcctt attcttaaat
    30241 ccacgtttac gaatctcttt ccacacttgt tcaatggggt tcatctctgg tgtgtatgga
    30301 agaataaatg caaagccaat attagtcgga atctttaagg tacttgattt atgccatata
    30361 gcattgtcca taacgagtaa aagataatca tctggataag cttgtgaaat ctcctattcc
    30421 taaagcccct ttagcgcata actttggctc agcttctatt atcgctcaca ccatccatca
    30481 gaagtttaat ctgaaggtac ccaattatcg ccaagaagaa gattgggcta ggatgggttt
    30541 accaatcaca cgtaaggaaa tctctaattg gcatatcaag acgagtcaat actatttgga
    30601 gcccctttat aacctcttgc gagagagact attgactcag cccttacttc atgcggatga
    30661 aacttcttat agggtgctag agagtgatag tcagctgact tactattgga cttttttgtc
    30721 tgggaaagct gagaaacaag ggattacgct ttaccatcat gtcctaatcg atttgttcat
    30781 atcttatttc aatccattat aaatagtgag aaatatctat cctatcttct agaatgtctt
    30841 ccaaacgtgg aaactctcgt aaacaaagag gttttagagg cctatttacc atggattaaa
    30901 gttgtacaag aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttctct
    30961 agtctggaga tttttcaata tacttcgtta ttggacggtt acaattcata aagtgctgta
    31021 gagagataac gttcaccgtt atctggtgct agggcaagga cttttttacc tgtacctaat
    31081 tttttggcaa cctcgatggc tccgtagata gctgcagctg aggaaatccc tacaaggaag
    31141 ccttcttttc caccaatttc acgtccgagt gcaagagcgt catctgatgt tacacgaacg
    31201 ataccatcat aggctttagt atcaagtgta tcaggaataa atccagctga gataccttga
    31261 attttgtgag gaccgggttt ttcaccagat agaatagcag attcatctgc ttctactgca
    31321 aaaacttgaa tgttagaatt ttctgatttg agtgcatgag aaacaccaga aatcgttcca
    31381 ccggtaccta ctccagcaac aaaggcatct aatccatctt taccgaaagc agctagtatc
    31441 tcagctcctg ttgttctttc gtgtacttct ggattagctg gattgtcaaa ttgaagagga
    31501 aggaaaccat cacgttcagc agcgatttct tgagccttag caatagcacc tttcattccc
    31561 tcgctaccag gagttaggac gagttcagca ccataagctt ggataatttt acgtcgttct
    31621 acactcatag tttcaggcat aacgatgacg actttatacc ctttagcagc acctacccat
    31681 gaaagtccaa taccagtgtt tccacttgtt gcttcaacaa tagtagaacc aggtttcaga
    31741 ataccatctt gttcagcttt ttcaatcatg ctaagggcaa tacggtcttt tacagatgaa
    31801 ccaggattaa atgcttcaag ctttatatag acgtctgcag caccttctgg cacgatgttg
    31861 ttaagtttaa caattggtgt ttgaccgatt aattcagtaa tgttgttata aatagacata
    31921 tgaatacctc tttgtataag atatctttag tataacgcta tctataccat ttgtaaaata
    31981 tagaaatcct atcgaagcga taggatttct atatatcata gatcaaagtc attaattttc
    32041 aagtgattgc gttcagctaa ttctagtaaa taggtgtgaa ggaaaacgat atcaggtttc
    32101 gtttgaattg cttcattttc tagtatattt tggtacgcat ctttttattt tgctcgctaa
    32161 agtagttgtg agaatgtcaa cgaaacgttg tattattcat tgtttacact aagtttacag
    32221 gaacttcaac ctctcgtaaa ccttggtcag ttaaagtgac ttttccatta aaaaactcca
    32281 caagtgcagc tttaatagtt tctttttctt ctttatcaac ataaatcatc gtatcgattt
    32341 gatctgtaaa gtttgtatcc agctccatga gatcatgttc tttaaggaag ttactgtact
    32401 cttggtactg agcataagac atttgaatag caatgccagc ctgttctttt atttcaataa
    32461 taccaatttc tttgacagct aaggcgacac tgccggcgta agcacgaatt agtcctccag
    32521 cgcctagttt aataccacca aagtagcgtg tcacgaccac acagacattg gtgagattgt
    32581 gattttctag taccccaagc atgggaacac cagcagtacc actaggttca ccatcatcac
    32641 ttgtacgttt aatttcacta cgttctccaa taataaaggc agagcagtta tgtgtcgctt
    32701 tgtagtgttc ttttttgatg gcagtaatga agtcacgagc ctcttcttcg ctataaacac
    32761 gcttggcatg gcagataaag cgagattttt tgatttcttc ttggacttga ccgtcctctt
    32821 taattgttct aaattccatg atttaattgt actaaaaaat catctaaagt gctagttttt
    32881 acgaataaag aagtatgaaa gtaaatttag attatctcgg tcgtttattt actgagaatg
    32941 aattaacaga agaagaacgt cagttggcgg agaaacttcc agcaatgaga aaggagaagg
    33001 ggaaactttt ctgtcaacgc tgtaatagta ttattctaga agaatggtat ttgcccatcg
    33061 gtgcttacta ttgtcgagag tgcttgctga tgaagcgagt cagaagtgat caaactttat
    33121 actattttcc gcaggaggat tttccgaagc aagatgttct caaatggcgc ggccaattaa
    33181 ctccttttca agagaaggtg tcagagggac tgcttcaagc agtagacaag caaaagccaa
    33241 ccttagttca tgcggtaaca ggagctggaa agacagaaat gatttatcaa gtagtggcta
    33301 aagtgatcaa tgcgggtggt gcagtgtgtt tggctagtcc tcgcatagat gtttgtttgg
    33361 agctgtacaa gcgcctgcaa caggattttt cttgcggaat agctttgcta catggagaat
    33421 cggaacctta ttttcgaaca ccactagttg ttgcaacaac ccatcagtta ttgaagtttt
    33481 atcaagcttt tgatttgctg atagtggatg aagtagatgc ttttccttat gttgataatc
    33541 ccatgcttta ccacgctgtc aagaatagtg taaaggagaa tggattgaga atctttttaa
    33601 cagcgacttc gaccaatgag ttagataaaa aggtccgttt aggagaacta aaaagactga
    33661 atttaccgag acggtttcat ggaaatccgt tgattattcc aaaaccaatt tggttatcgg
    33721 attttaatcg ctacttagac aagaatcgtt tgtcaccaaa gttaaagtcc tatattgaga
    33781 agcagagaaa gacagcttat ccgttactca tttttgcttc agaaattaag aaaggggagc
    33841 agttagcaga aatcttacag gagcaatttc caaatgagaa aattggcttt gtatcttctg
    33901 taacagagga tcgattagag caagtacaag cttttcgaga tggagaactg acaatactta
    33961 tcagtacgac aatcttggag cgtggagtta ccttcccttg tgtggatgtt ttcgtagtag
    34021 aggccaatca tcgtttgttt accaagtcta gtttgattca gattggtgga cgagttggac
    34081 gaagcatgga tagaccgaca ggagatttgc ttttcttcca tgatgggtta aatgcttcaa
    34141 tcaagaaggc gactaaggaa attcagatga tgaataagga ggctggtcta tgaagtgctt
    34201 gttatgtggg cagactatga agactgtttt aacttttagt agtctcttac ttctgaggaa
    34261 tgatgactct tgtctttgtt cagactgtga ttctactttt gaaagaattg gggaagagaa
    34321 ctgtccaaat tgtatgaaaa cagagttgtc aacaaagtgt caagattgtc aactttggtg
    34381 taaagaggga gttgaagtca gtcatagagc gatttttact tacaatcaag ctatgaagga
    34441 ttttttcagt cggtataagt ttgatggaga cttcctgtta agaaaagttt tcgcttcatt
    34501 tttaagtgag gagttgaaaa agtacaaaga gtatcaattt gttgtaattc ccctaagtcc
    34561 tgatagatat gctaatagag gatttaatca ggttgagggc ttggtagagg cagcaggctt
    34621 tgagtatctg gatttattag agaaaagaga agagagagcc agttcttcta aaaatcgttc
    34681 agagcgcttg gggacagaac ttcctttctt tattaaaagt ggagtcacta ttcctaaaaa
    34741 aatcctactt atagatgata tctatactac aggagcaact ataaatcgtg ttaagaaact
    34801 gttggaagaa gctggtgcta aggatgtaaa aacattttcc cttgtaagat gaggaaaaaa
    34861 tttgcaaaaa tagaatgaaa gcgttataat aaaatcataa aaacaaaaat gtttagaaag
    34921 aaggtactca tatgattaaa tatagtatcc gtggtgaaaa cctagaagta acagaagcaa
    34981 ttcgtgatta tgtagtttct aaactcgaaa agatcgaaaa gtacttccaa ccagaacaag
    35041 agttggatgc ccgaattaac ttaaaagttt atcgtgaaaa aacggctaaa gtggaagtaa
    35101 cgattccgct tggatctatt actctccgcg cagaagatgt atctcaagat atgtatggtt
    35161 caattgacct tgtaactgat aaaattgaac gtcagattcg taaaaataaa acaaaaatcg
    35221 agcgtaaaaa taaaaataag gtagcaactg gtcaattatt tacagatgct ttggtggaag
    35281 attcaaatgt tgtccagtct aaagttgttc gttcaaaaca aattgattta aaaccaatgg
    35341 atttggaaga agcaattcta caaatggatt tattggggca tgatttcttt atctatgtgg
    35401 atgttgaaga tcagacaacc aatgtgattt atcgtcgtga ggatggcgaa attggtttgt
    35461 tagaggttaa agaatcttaa tttcaatatg tgtaaaggta ggtttactga attgtaaact
    35521 acctttttct tataattgat agaattactg attacacttt taaaaagtcg ctttttgagg
    35581 ggtattatgg tataatgggt gccaagaggt tttgaatgaa aaaattttat gtaagtccaa
    35641 tttttcctat tctagtagga ttgattgcgt ttggagtctt atccactttc attatttttg
    35701 ttaataataa tctgttgacg gttttaattt tgtttctttt tgtaggaggc tatgtttttt
    35761 tatttaagaa actgagagtg cattatacaa ggagtgatgt agaacagata cagtatgtaa
    35821 accaccaagc ggaagaaagt ttgacagctc tattggaaca gatgcctgta ggtgttatga
    35881 aattgaattt atcttctgga gaggttgagt ggtttaatcc ctatgctgaa ttgattttga
    35941 ccaaggaaga tggtgatttt gatttagaag ctgttcaaac gattatcaag gcttcagtag
    36001 gaaatccgtc tacttatgcc aagcttggtg agaagcgtta tgctgttcat atggatgctt
    36061 cttccggtgt tttgtatttt gtagatgtat ccagggaaca agccataaca gatgaattgg
    36121 taacaagtag accagtgatt gggattgtct ctgtggataa ttatgatgat ttggaggatg
    36181 aaacttctga gtcagatatt agtcaaatca atagttttgt agctaatttt atatcagagt
    36241 tttcagaaaa acacatgatg ttttctcgtc gggtaagtat ggatcgattt tatctattta
    36301 ctgactacac ggtgcttgag ggcttgatga atgataaatt ttctgttatt gatgctttca
    36361 gagaagagtc gaaacagaga cagttgccct tgaccttaag tatgggattt tcttatggcg
    36421 atggaaatca tgatgagata gggaaagttg ctttgctcaa tttgaacttg gctgaagtac
    36481 gtggtggcga ccaggtggtt gttaaggaaa acgacgaaac gaaaaatcca gtttattttg
    36541 gtggtgggtc tgctgcttca atcaagcgta cacggactcg tacgcgcgct atgatgacag
    36601 ctatttcaga taagattcgg agtgtagatc aggtttttgt agtcggtcac aaaaatttag
    36661 acatggatgc tttgggctct gctgtaggta tgcagttgtt cgccagcaat gtgattgaaa
    36721 atagctatgc tctttatgat gaagaacaaa tgtctccaga tattgaacga gctgtttcat
    36781 tcatagaaaa agaaggagtt acgaagttgt tgtctgttaa ggatgcaatg gggatggtga
    36841 ccaatcgttc tttgttgatt cttgtagacc attcaaagac agccttaaca ttatcaaaag
    36901 aattttatga tttatttacc caaaccattg ttattgacca ccatagaagg gatcaggatt
    36961 ttccagataa tgcggttatt acttatatcg aaagtggtgc aagtagtgcc agtgagttgg
    37021 taacggaatt gattcagttc cagaattcta agaaaaatcg tttgagtcgt atgcaagcaa
    37081 gtgttttgat ggctggtatg atgttggata ctaaaaattt cacctcgcga gtaactagtc
    37141 ggacatttga tgttgctagc tatctcagaa cgcgcggaag tgatagtatt gctatccagg
    37201 aaatcgctgc gacagatttt gaagaatatc gtgaggtcaa tgaacttatt ttacaggggc
    37261 gtaaattagg ttcagatgta ctaatagcag aggctaagga cacgaaatgc tatgatacag
    37321 ttgttattag taaggcagca gatgccatgt tagccatgtc aggtattgaa gcgagttttg
    37381 ttcttgcgaa gaatacacaa ggatttatct ctatctcagc tcgaagtcgt agtaaactga
    37441 atgtacaacg gattatggaa gagttaggcg gtggaggcca ctttaatttg gcagcagctc
    37501 aaattaaaga tgtaaccttg tcagaagcag gtgaaaaact gacagaaatt gtattaaatg
    37561 aaataaagga aaaggagaaa gaagaatgaa agtaatcttt ttagcagatg ttaaaggaaa
    37621 aggtaaaaaa ggcgaaatta aggaagtacc aacagggtat gcgcaaaact ttcttatcaa
    37681 aaagaatcta gccaaagaag cgactgctca agctgtaggt gaacttcgag gtaaacaaaa
    37741 atcggaagaa aaagctcacg ctgagatgat tgcagaagga aaagcaatta aagcacaact
    37801 tgaagcagaa gaaactgttg tagaatttgt tgaaaaagtt ggtccagatg gtcgtacctt
    37861 tggttctatt accaataaga agattgcaga agaattgcaa aagcaatttg gaattaagat
    37921 tgataaacgt catattcaag tacaagctcc gattcgagcg gttggtttga ttgatgtgcc
    37981 agtgaaaatc tatcaagata tcacaagtgt aatcaatctt cgtgtgaaag aaggataagt
    38041 ttacactttc ttgacaagat tgtaaaagga agggaagtct gatggcagaa gtagaagagt
    38101 tacgagtaca acctcaagat atcttagctg agcaatccgt tttaggggct atctttattg
    38161 atgagagtaa acttgttttt gtgcgagaat acattgagtc tcgggacttt tttaagtatg
    38221 cccatcgttt gattttccaa gccatggtcg atttatccga tcgtggtgat gccatagatg
    38281 caacaacggt tcgtactatc cttgataatc aaggtgattt acagaatatt ggtggcttgt
    38341 cttacttggt tgagattgtt aattctgtgc caacttctgc taatgcggag tattatgcta
    38401 agattgttgc agaaaaagca atgctacgtc gtttaattgc caagttgaca gagtctgtca
    38461 accaagctta cgaagcgtca caaccagctg atgaaattat tgctcaggca gaaaaagggc
    38521 tgattgatgt cagtgaaaat gcaaatcgaa gcgggtttaa gaacattcga gatgtgttga
    38581 atctcaactt tggaaatctg gaagctcgct cgcaacaaac gaccgatatt acaggtattg
    38641 cgacaggtta tcgtgatttg gatcatatga caacaggact tcatgaggag gagttgatta
    38701 tcttagcagc tcgtccagca gttggtaaga cagcatttgc cttgaatatc gctcagaaca
    38761 ttgggactaa gttggacaaa acggttgcta ttttttcact cgaaatgggt gcggaaagct
    38821 tggtagatcg tatgttagct gcagaaggct tagtggagtc acattctatc cgtacagggc
    38881 aattgacaga tgaggagtgg caaaaatata ctattgctca gggtaatcta gctaacgcca
    38941 gtatctatat cgatgatacg ccaggtattc ggattacaga gattcgttct cgttctcgta
    39001 aattggctca agaaactgga aatcttggtt tgattttgat agactatttg caacttatca
    39061 cgggaactgg tcgagaaaat cgtcaacaag aagtttctga aatttctcgt cagttgaaaa
    39121 tactagccaa ggaattgaag gttccagtaa tcgctctgag tcagctttct cgtggtgtag
    39181 aacaacgtca ggacaagaga ccggtcttgt ctgatattcg tgaatctggg tctattgagc
    39241 aggacgctga tatcgtagct tttctctatc gcgatgacta ctatgaacgt ggtggtgaag
    39301 aagaggaggg tatcccaaat aataaggtgg aagttattat cgagaaaaac cgtagtggag
    39361 ctcgtggaac agtggaattg attttccaaa aagaatacaa taaattttca agtatctcaa
    39421 agagggaggc ataagatgtc agatgcattt acagatgtag ccaagatgaa aaaaatcaaa
    39481 gaagaaatca aggcacatga gggacaagtc gtagaaatga ctttggagaa tggtcgtaag
    39541 cgccaaaaaa atagattggg taagctaatt gaagtttatc catctctatt tattgtggag
    39601 tttggggatg tggaaggaga taaacaagtt aatgtttacg ttgaatcctt tacttactca
    39661 gatattctta cagaaaagaa tttgattcat tatcttgact aaagtgagaa attttctcac
    39721 tttttctttt ttctccgaat aatttaggtg aaggcaatca tcgctttata ttatttttca
    39781 aggaggaaga atgaaaattt taccgtttat agcaagagga acaagttatt acttgaagat
    39841 gtcagttaaa aagcttgttc cttttttagt agtaggattg atgctagcag ctggtgatag
    39901 tgtctatgcc tattccagag gaaatggatc gattgcgcgt ggggatgatt atcctgctta
    39961 ttataaaaat gggagccagg agattgatca gtggcgcatg tattctcgtc agtgtacttc
    40021 ttttgtagcc tttcgtttga gtaatgtcaa tggttttgaa attccggcag cttatggaaa
    40081 tgcgaatgaa tggggacatc gtgctcgtcg ggaaggttat cgtgtagata atacaccgac
    40141 gattggttcc attacttggt ctactgcagg aacttatggt catgttgcct gggtgtcaaa
    40201 tgtaatggga gatcagattg agattgagga atataactat ggttatacag aatcctataa
    40261 taaacgagtt ataaaagcaa acacgatgac aggatttatt cattttaaag atttggatgg
    40321 cggcagtgtt gggaatagtc aatcctcagc ttcaacaggc ggaactcatt attttaagac
    40381 caagtctgct attaaaactg aacccctagc tagcggaact gtgattgatt actattatcc
    40441 tggggagaag gttcattatg atcagatact tgaaaaagac ggctataagt ggttgagtta
    40501 tactgcctat aatggaagct atcgttatgt tcaattggag gctgtgaata aaaatcctct
    40561 aggtaattct gttctttctt caacaggtgg aactcattat tttaagacca agtctgctat
    40621 caaaactgaa cccctagtta gcggaactgt gattgattac tattatcctg gggagaaggt
    40681 tcattatgat cagatacttg aaaaagacgg ctacaagtgg ttgagttata ctgcctataa
    40741 tggaagtcgt cgctatatac agctagaggg agtgacttct tcacaaaatt atcagaatca
    40801 atcaggaaat atctctagct atggatccaa taatagttca actgtcggtt ggaagaaaat
    40861 aaatggtagt tggtatcatt tcaaatcaaa tggttctaaa tcaacaggat ggctgaaaga
    40921 cggttctagc tggtattatt tgaaattatc tggtgaaatg cagacaggat ggttaaagga
    40981 aaatggctcg tggtattatc tgggtagttc aggggcaatg aaaacaggct ggtaccaggt
    41041 ctctggtaag tggtattatt cttactcttc aggcgcctta gctgttaata cgacggtgga
    41101 tggctacaga gtaaacagtg atggagaacg agtatagaaa attggagtag gagaaatttc
    41161 ctgctctttt ctgtaagcag tttccttgac atttttctta ttttgcgcta tcatatatac
    41221 atataatata tgggagtctg tgtacagtct gagaggaagt gttaaacttc gaccgcacct
    41281 gatctgggta atgccagcgg agggaacgat acttagtcta attttgcacc ttttccatgt
    41341 atggtaaagg tttttctttt tttaaaaagg aaaacgagaa gaggaggttc ttatgaaagc
    41401 aagcattgcc ttgcaagttt tacccctagt acaggggatt gatcggatag ctgttattga
    41461 tcaggtcatt gcttatctgc aaactcaaga agtgccgatg gtagtgacac catttgaaac
    41521 ggtcttggaa ggggagtttg atgagcttat gcgcattcta aaagaagcgc tggaagtggc
    41581 agggcaggag gcagacaatg tctttgccaa tgtcaaaata aatgtaggag agattttaag
    41641 tattgatgag aaacttgaga agtatactga gacgacacat tagtctattg ggctttctcg
    41701 gagtcttgtc aatctggcag ttagcaggtt ttcttaaact gctccccaag tttatcctgc
    41761 cgacacctct tgaaattctc cagccctttg ttcgtgacag agaatttctc tggcaccata
    41821 gctgggcgac cttgagagtg gctttactgg ggctgatttt gggagttttg attgcctgtc
    41881 ttatggctgt actcatggat agtttgactt ggctcaatga cctgatttac cctatgatgg
    41941 tggtcattca gaccattccg accattgcca tagctcctat cctggtcttg tggctaggtt
    42001 atgggatttt gcccaagatt gtcttgatta tcttaacgac aacctttccc atcatcgtca
    42061 gcattttgga cggttttagg cattgcgaca aggatatgct gactttgttt agtctgatgc
    42121 gggccaagcc ttggcaaatc ctgtggcatt ttaaaattcc agtcagcctg ccctactttt
    42181 atgctggtct gagggtcagt gtctcctacg cttttatcac aacagtggta tctgagtggt
    42241 tgggaggctt tgaggggctt ggtgtttata tgattcagtc caagaaattg tttcagtatg
    42301 ataccatgtt cgctattatt attctggtat cgattatcag ccttttgggt atgaagttgg
    42361 tcgatattag tgaaaaatat gttattaaat ggaaacgttc gtagaattag aatgtttctg
    42421 aaaaagaaaa gaggaaatca aaatgaagaa aacatggaaa gtgtttttaa cgcttgtaac
    42481 agctcttgta gctgttgtgc ttgtggcctg tggtcaagga actgcttcta aagacaacaa
    42541 agaggcagaa cttaagaagg ttgactttat cctagactgg acaccaaata ccaaccacac
    42601 agggctttat gttgccaagg aaaaaggtta tttcaaagaa gctggagtgg atgttgattt
    42661 gaaattgcca ccagaagaaa gttcttctga cttggttatc aacggaaagg caccatttgc
    42721 agtgtatttc caagactaca tggctaagaa attggaaaaa ggagcaggaa tcactgccgt
    42781 tgcagctatt gttgaacaca atacatcagg aatcatctct cgtaaatctg ataatgtaag
    42841 cagtccaaaa gacttggttg gtaagaaata tgggacatgg aatgacccaa ctgaacttgc
    42901 tatgttgaaa accttggtag aatctcaagg tggagacttt gagaaggttg aaaaagtacc
    42961 aaataacgac tcaaactcaa tcacaccgat tgccaatggc gtctttgata ctgcttggat
    43021 ttactacggt tgggatggta tccttgctaa atctcaaggt gtagatgcta acttcatgta
    43081 cttgaaagac tatgtcaagg agtttgacta ctattcacca gttatcatcg caaacaacga
    43141 ctatctgaaa gataacaaag aagaagctcg caaagtcatc caagccatca aaaaaggcta
    43201 ccaatatgcc atggaacatc cagaagaagc tgcagatatt ctcatcaaga atgcacctga
    43261 actcaaggaa aaacgtgact ttgtcatcga atctcaaaaa tacttgtcaa aagaatacgc
    43321 aagcgacaag gaaaaatggg gtcaatttga cgcagctcgc tggaatgctt tctataaatg
    43381 ggataaagaa aatggtatcc ttaaagaaga cttgacagac aaaggcttca ccaacgaatt
    43441 tgtgaaataa tgacagaaat tagactagag cacgtcagtt atgcctatgg tcaggagagg
    43501 attttagagg atatcaacct acaggtgact tcaggcgaag tggtttccat cctaggccca
    43561 agtggtgttg gaaagaccac cctctttaat ctaatcgctg ggattttaga agttcagtca
    43621 gggagaattg tccttgatgg tgaagaaaat cccaaggggc gcgtgagtta tatgttgcaa
    43681 aaggatctgc tcttggagca caagacggtg cttggaaata tcattctgcc cctcttgatt
    43741 caaaaggtgg ataaggcaga agctatttcc cgagcggata aaattcttgc gaccttccag
    43801 ctgacagctg taagagacaa gtatcctcat gaacttagcg gtgggatgcg ccagcgtgta
    43861 gccttactcc ggacctacct ttttgggcac aagctctttc tcttagatga ggcctttagc
    43921 gccttggatg agatgacaaa gatggaactc cacgcttggt atcttgagat tcacaagcag
    43981 ttgcagctaa caaccctgat catcacgcat agtattgagg aggccctcaa tctcagcgac
    44041 cgcatctata tcttgaaaaa tcgccctggg cagattgttt cagaaattaa actagattgg
    44101 tctgaagatg aggacaagga agtccaaaag attgcctaca aacgtcaaat cttggcagaa
    44161 ttaggcttag ataagtagaa aaatagggag ttggtgaaga ttatccttta ccagcgccct
    44221 ttttctttta aaaatgagaa aatttcggta taatagtcaa acaaggtcaa ggtttaaaga
    44281 gagaggtggg tttgttatga gatttaaaaa tacatcggat catattgagg cctacatcaa
    44341 ggcgatttta gatcaatctg gtatcgtgga gttgcaacgg agtcagttgg cagatacctt
    44401 tcaggttgtt cctagtcaga ttaactacgt gatcaagaca cgctttacgg aaagtagagg
    44461 ctacttggtt gaaagtaagc gtggtggcgg aggctacatt cgtataggac ggattgagtt
    44521 ttctagtcat catgaaatgc tccgggagct gctttactcg attggtgagc gagtcagtca
    44581 agaaatttat gaggatattc tccagctttt ggttgagcag gaattgatga ccaagcagga
    44641 gatgaatttg ctagaatcag tagctttgga tcgcgtttta ggagaagaag ctccagttgt
    44701 tcgagcaaac atgctacgtc agatcataca agaggtagat agaaaaggga agtaagatga
    44761 actattcaaa agcattgaat gaatgtatcg aaagtgccta catggttgct ggacattttg
    44821 gagctcgtta tctagagtct tggcacttgt tgattgccat gtctaatcac agttatagtg
    44881 tagcaggggc aactttaaat gattatccgt atgagatgga ccgtttagaa gaggtggctt
    44941 tggaactgac tgaaacggac tatagccagg atgaaacctt tacggaattg ccgttctccc
    45001 gtcgtttgca ggttcttttt gacgaagcag agtatgtagc gtcagtggtc catgctaagg
    45061 tgctagggac agagcacgtc ttctatgcga ttttgcatga tggcaatgcc ttggcaactc
    45121 gtatcttgga gagggctggt ttttcttatg aagacaagaa agatcaggtc aagattgctg
    45181 ctcttcgtcg aaatttagaa gaacgggcag gctggactcg tgaagatctc aaggctttac
    45241 gccaacgcca tcgtacagta gctgacaagc aaaattctat ggccaatatg atgggcatgc
    45301 cgcagactcc tagtggtggt ctcgaggatt atacgcatga tttgacagag caagcgcgtt
    45361 ctggcaagtt agaaccagtc atcggtcggg acaaggaaat ctcacgtatg attcaaatct
    45421 tgagccggaa gactaagaac aaccctgtct tggttgggga tgctggtgtc gggaaaacag
    45481 ctctggcgct tggtcttgcc cagcgtattg ctagtggtga cgtgcctgcg gaaatggcta
    45541 agatgcgcgt gttagaactt gatttgatga atgtcgttgc agggacacgc ttccgtggtg
    45601 actttgaaga acgcatgaat aatatcatca aggatattga agaagatggc caagtcatcc
    45661 tctttatcga tgaactccac accatcatgg gttctggtag cggaattgat tcgactctgg
    45721 atgcggccaa tatcttgaaa ccagccttgg cgcgtggaac tttgagaacg gttggtgcca
    45781 ccactcagga agaatatcaa aaacatatcg aaaaagatgc ggctctttct cgtcgtttcg
    45841 ctaaagtgac gattgaagaa ccaagtgtgg cagatagtat gactatttta caaggtttga
    45901 aggcgactta tgagaaacat caccgtgtac aaatcacaga tgaagcggtt gaaacagcgg
    45961 ttaagatggc tcatcgttat ttaaccagtc gtcacttgcc agactctgct atcgacctct
    46021 tggacgaagc agcagcaaca gtgcaaaata aggcaaagca tgtaaaagca gacgattcag
    46081 atttgagtcc agctgacaag gccctgatgg atggcaagtg gaaacaggca gcccagctaa
    46141 tcgcaaaaga agaggaagta cctgtctaca aagacttggt gacagagtct gatattttga
    46201 ccaccttgag tcgcttgtca ggaatcccag ttcaaaaact gactcaaacg gatgctaaga
    46261 agtatttaaa tcttgaagca gaactccata aacgtgtcat cggtcaagat caagctgttt
    46321 caagtattag tcgtgccatt cgccgtaatc agtcaggaat tcgcagtcac aagcgtccga
    46381 tcggttcctt tatgttccta ggacccacag gtgtcggtaa gaccgagttg gccaaggctt
    46441 tggcagaagt tctctttgat gacgaatcag cccttatccg ctttgatatg agtgagtata
    46501 tggagaaatt cgcagccagc cgtctaaatg gagctcctcc aggctatgtg ggttacgaag
    46561 aaggtgggga gctgacagag aaggttcgca ataaacccta ttccgttctc ctctttgatg
    46621 aggtagagaa ggcccaccca gatatcttta atgttctctt gcaggttctg gatgacggtg
    46681 tcttgacaga tagcaaggga cgcaaggtcg atttttcaaa taccattatc attatgacat
    46741 cgaatctagg tgcgactgcc cttcgtgatg ataagactgt tggttttggg gctaaggata
    46801 ttcgttttga ccaggaaaat atggaaaaac gcatgtttga agaactgaaa aaagcttata
    46861 gaccggaatt catcaaccgt attgatgaga aggtggtctt ccatagccta tctagtgacc
    46921 atatgcagga agtggtgaag attatggtca agcctttagt ggcaagtttg gctgaaaaag
    46981 gcattgactt gaaattacaa gcttcagctc tgaaattgtt agcaaatcaa ggatatgacc
    47041 cagagatggg agctcgccca cttcgcagaa ccctgcaaac agaagtggag gacaagttgg
    47101 cagaacttct tcttaaggga gatttagtgg caggcagcat acttaagatt ggtgtcaaag
    47161 caggccagtt aaaatttgat attgcataaa agaataaaag tatcagcatc tgaccataag
    47221 tcacagtgga gtgaaactca atgaaaatca aagagcaaac taggcagcta gccgcaggtt
    47281 gctcaaaaca ctgttttgag gttgcagata gagctgacgt ggtttgaaga gattttcgaa
    47341 gagtataagc tgcaagatga atgattttct tgtattgacg ttgttgttga caaaaagtag
    47401 cggataaatg aaatccattc cattatcata gatgatagac tggtaggaaa ttttcaaata
    47461 gcatacagga aatagatgta tggagttctg gtagtagaaa gggagagaga tgaacatttt
    47521 agttgcagat gacgaggaaa tgattagaga aggaattgca gcatttctga cagaagaggg
    47581 ttatcatgtc attatggcta aggatggaca agaggtcttg gaaaaatttc aagatctccc
    47641 tatccatctc atggtactgg atttaatgat gcctaggaag agtggttttg aagtgttaaa
    47701 agaaatcaat caaaagcacg atattcctgt catcgtcttg agtgctctgg gagatgaaac
    47761 tactcagtca caggtatttg atctctatgc tgatgatcat gtgacaaaac ctttttcttt
    47821 ggtactgctt gtcaagcgta ttaaggcgct tatcagacgt tactacgtca tagaggatat
    47881 ttggcgatat caggatgtaa cagtggattt tacctcttac aaagcacatt ataaaaatga
    47941 agaaattgat ctcaaaccaa aggaattact ggtactaaag tgtttgattc agcataaaaa
    48001 tcaagtttta agtagagagc agatattgga agaaatttca aaagatgtag ctgatttacc
    48061 ttgtgatagg gtcgttgatg tctatattcg tactcttcgc aaaaaattag ctttagattg
    48121 tatcgtgact gtgaaaaatg ttgggtataa gattagttta tgataaaaaa tcctaaatta
    48181 ttaaccaagt cctttttaag aagttttgca attctaggtg gtgttggtct agtcattcat
    48241 atagctattt atttgacctt tcctttttat tatattcaac tggaggggga aaagtttaat
    48301 gagagcgcaa gagtgtttac ggagtattta aagactaaga catctgatga aattccaagc
    48361 ttactccagt cttattcaaa gtccttgacc atatctgctc accttaaaag agatattgta
    48421 gataagcgac tccctcttgt gcatgacttg gatattaaag atggaaagct atcaaattat
    48481 atcgtgatgt tagatatgtc tgttagtaca gcagatggta aacaggtaac cgtgcaattt
    48541 gttcacgggg tggatgtcta caaagaagca aagaatattt tgcttttgta tctcccatat
    48601 acatttttgg ttacaattgc tttttccttt gttttttctt atttttatac taaacgcttg
    48661 ctcaatcctc ttttttacat ttcagaagtg actagtaaaa tgcaagattt ggatgacaat
    48721 attcgttttg atgaaagtag gaaagatgaa gttggtgaag ttggaaaaca gattaatggt
    48781 atgtatgagc acttgttgaa ggttattcat gagttggaaa gtcgtaatga gcaaattgta
    48841 aaattgcaaa atcaaaaggt ttcctttgtc cgtggagcat cacatgagtt gaaaacccct
    48901 ttagccagtc ttagaattat cctagagaat atgcagcata atattggaga ttacaaagat
    48961 catccaaaat atattgcaaa gagtataaat aagattgacc agatgagcca cttattggaa
    49021 gaagtactgg agtcttctaa attccaagag tggacagagt gtcgtgagac cttgactgtt
    49081 aagccagttt tagtagatat tttatcacgt tatcaagaat tagctcattc aataggtgtt
    49141 acaattgaaa atcaattgac agatgctacc agggtcgtca tgagtcttag ggcattggat
    49201 aaggttttga caaacctgat tagtaatgca attaaatatt cagataaaaa tgggcgtgta
    49261 atcatatctg agcaagatgg ctatctctct atcaaaaata catgtgcgcc tctaagtgac
    49321 caagaactag aacatttatt tgatatattc tatcattctc aaatcgtgac agataaggat
    49381 gaaagttccg gtttgggtct ttacattgtg agtaatattt tagaaagcta tcaaatggat
    49441 tatagttttc tcccttatga acacggtatg gaatttaaga ttagcttgta gacagattag
    49501 ttttttatta aagttcacat agggttaaca taagtgtatt attctttata tagataaaaa
    49561 tatagataaa agaaaggata ctaatatggt attagcgatt attttagtaa cattccttat
    49621 tcgattgatt tttttaaagc gttcgataga gaatgagaaa cgaatcctta gcaatggcgg
    49681 gaaagaattt ggagttgaga atacaaaacg attaacgttg gctcatattg ttttttatct
    49741 ctcttgcctc gttgaagcaa tggtgcataa gacaatgttt gatggcatgg gcatggttgg
    49801 tttggtcttg cttatttttt ctatgctgat gttgatgttg gtgattcact tgttgggaga
    49861 tatttggaca gtgaagctta tgcttgtcaa taatcacaaa tatgtagatc atatcttgtt
    49921 taggacagta aaacacccta attacttttt aaatatttta cctgagttga ttggcttgac
    49981 cttgttgagt catgcctata tgacttttgt tttagttttt ccagtttatg cagttatttt
    50041 gtatcgacga atagctgaag aggaaaagct attacatgaa gttataatcc caaatggaag
    50101 cataaagaga taaatacaaa attcgattta tatacagttc atattgaagt gatatagtaa
    50161 ggttaaagaa aaaatataga aggaaataaa catgtttgca tcaaaaaacg aaagaaaagt
    50221 acattattca attcgtaaat ttagtattgg agtagctagt gtagctgttg ccagtctttt
    50281 tatgggaagt gtggttcatg cgacagagaa ggaggtaact acccaagtag ccacttcttc
    50341 taataaggca aataaaagtc agacagaaca tatgaaagct gctaaacaag tcgatgaata
    50401 tataaaaaaa aagctccaat tagatagaag aaaacatacc caaaatgtcg gcttactcac
    50461 aaagttgggc gtaattaaaa cggagtattt gcatggatta agtgtttcaa aaaagaagtc
    50521 ggaagctgag ttgccgtcag aaataaaagc aaagttagac gcagcttttg agcagtttaa
    50581 aaaagataca ttaccaacag aaccaggaaa aaaggtagca gaagctgaga agaaggttga
    50641 agaagctaag aaaaaagccg aggatcaaaa agaaaaagat ctccgtaact acccaaccaa
    50701 tacttacaaa acgcttgaac ttgacattgc tgagtccgat gtggaagtta aaaaagcgga
    50761 gcttgaacta gtaaaagagg aagctaagga atctcgagac gagaaaaaaa ttaatcaagc
    50821 aaaagcgaaa gttgagaata aaaaagctga ggctacaagg ttaaaaaaca tcaagacaga
    50881 tcgtgaaaaa gcagaagaag ctaaacgaag agcagatgct aagttgcagg aagctaatgt
    50941 agcgacttca gagcaagata aatcaaagag gcgggcaaaa cgagaagttc ttggagagct
    51001 agcaacacct gataaaaaag aaaatgatgc gaagtcttca gattctagcg taggtgaaga
    51061 aactcttaca agcccatccc tgaaaccaga aaaaaaggta gcagaagctg agaagaaggt
    51121 tgaagaagct aagaaaaaag ccgaggatca aaaagaagaa gatcgtcgta actacccaac
    51181 caatacttac aaaacgcttg aacttgaaat tgctgagtcc gatgtggaag ttaaaaaagc
    51241 ggagcttgaa ctagtaaaag aggaagctaa ggaatctcga aacgaggaaa aaattaagca
    51301 agtaaaagcg aaagttgaga gtaaaaaagc tgaggctaca aggctagaaa acatcaagac
    51361 agatcgtaaa aaagcagaag aagaagaagc taaacgaaga gcagcagaag aagataaagt
    51421 taaagaaaaa ccagctgaac aaccacaacc agcgccggct cctcaaccag aaaaaccaac
    51481 tgaagagcct gagaatccag ctccagctcc agctccaaaa ccagagaatc cagctgaaaa
    51541 accaaaagca gaaaagccag ctgatcaaca agctgaagaa gactatgctc gtagatcaga
    51601 agaagaatat aaccgcttga ctcaacagca accgccaaaa gcagaaaaac cagcacaacc
    51661 atctactcca aaaacaggct ggaaacaaga aaatggtatg tggtacttct acaatactga
    51721 tggttcaatg gcgacaggat ggctccaaaa caatggctca tggtactacc tcaacagcaa
    51781 tggcgctatg gcgacaggat ggctccaaaa caatggttca tggtactatc taaacgctaa
    51841 tggttcaatg gcaacaggat ggctccaaaa caatggttca tggtactacc tcaacgctaa
    51901 tggttcaatg gcgacaggat ggctccaata caatgg
//
LOCUS       DAVLIK010000010        50487 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLIK010000010 DAVLIK010000000
VERSION     DAVLIK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.010"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(240..377)
                     /locus_tag="VXE87_000613"
                     /pseudo
     CDS             complement(240..377)
                     /locus_tag="VXE87_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(755..1444)
                     /gene="rplA"
                     /locus_tag="VXE87_000614"
     CDS             complement(755..1444)
                     /gene="rplA"
                     /locus_tag="VXE87_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0842203.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1652..2077)
                     /gene="rplK"
                     /locus_tag="VXE87_000615"
     CDS             complement(1652..2077)
                     /gene="rplK"
                     /locus_tag="VXE87_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0842204.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2209..2346
                     /locus_tag="VXE87_000616"
     CDS             2209..2346
                     /locus_tag="VXE87_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842205.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(2386..3102)
                     /locus_tag="VXE87_000617"
     CDS             complement(2386..3102)
                     /locus_tag="VXE87_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0842206.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3105..3575)
                     /locus_tag="VXE87_000618"
     CDS             complement(3105..3575)
                     /locus_tag="VXE87_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0842207.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLEKETRLRFLEEMSLIQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(3577..4614)
                     /locus_tag="VXE87_000619"
     CDS             complement(3577..4614)
                     /locus_tag="VXE87_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0842208.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDGQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KEQNIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYIKSALVD"
     gene            complement(4712..6037)
                     /gene="brnQ"
                     /locus_tag="VXE87_000620"
     CDS             complement(4712..6037)
                     /gene="brnQ"
                     /locus_tag="VXE87_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0842209.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6208..6300)
                     /locus_tag="VXE87_000621"
     CDS             complement(6208..6300)
                     /locus_tag="VXE87_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0842210.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6343..6495)
                     /locus_tag="VXE87_000622"
     CDS             complement(6343..6495)
                     /locus_tag="VXE87_000622"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0842211.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6655..7233)
                     /locus_tag="VXE87_000623"
     CDS             complement(6655..7233)
                     /locus_tag="VXE87_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0842212.1"
                     /translation="MSQIERIKQAIMSDPQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYQNYLPTYFPLV
                     HPSPRNQIWMAKNPWFESEVVPDLKKRIKTIL"
     gene            complement(7287..8687)
                     /gene="pepV"
                     /locus_tag="VXE87_000624"
     CDS             complement(7287..8687)
                     /gene="pepV"
                     /locus_tag="VXE87_000624"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0842213.1"
                     /translation="MTVIDFTAEVEKRKEDLLADLFSLLEINSERDDSKVDAEHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFADPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8701..9306)
                     /locus_tag="VXE87_000625"
     CDS             complement(8701..9306)
                     /locus_tag="VXE87_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0842214.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNLILGFDKSK
                     VNEVLDIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            complement(9293..9475)
                     /locus_tag="VXE87_000626"
     CDS             complement(9293..9475)
                     /locus_tag="VXE87_000626"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842215.1"
                     /translation="MSPFKCKVLASLSETVLMHQYISFMAVIKKLNHGKYLQALSKYG
                     RMEAVELEKEIDYEIS"
     gene            9477..10277
                     /locus_tag="VXE87_000627"
     CDS             9477..10277
                     /locus_tag="VXE87_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0842216.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKATNSQKTIVVATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10457..11290)
                     /locus_tag="VXE87_000628"
     CDS             complement(10457..11290)
                     /locus_tag="VXE87_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0842217.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDCVLEVLDGQYGLENPQEIQLIRMTQFLMERMDPV
                     TIVWLRSLPMLEKKEVEGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDDEVDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNILFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11280..13127)
                     /gene="uvrC"
                     /locus_tag="VXE87_000629"
     CDS             complement(11280..13127)
                     /gene="uvrC"
                     /locus_tag="VXE87_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0842218.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYYNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKVLVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQRDGLTPPDLI
                     VIDGGQGQVNIAKQVIQDELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQEAEALPQVAEKQVDYQTEGEHNES"
     gene            complement(13166..13867)
                     /locus_tag="VXE87_000630"
     CDS             complement(13166..13867)
                     /locus_tag="VXE87_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0842219.1"
                     /translation="MRWLFRLIGGFFSFVWRLFWRLVWLVVLLCALAFGLLWYLNGDF
                     QEALKQAERSVKIGQQSIDQWEKTGQLPKLNQTDSHQHSEGRWPQASARIYLDPQMDS
                     HFQEAYVEAIQNWNQTGAFNFEIVTESSKADILATEVNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPDYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVERLRKLYETNE"
     gene            complement(13946..15178)
                     /gene="murN"
                     /locus_tag="VXE87_000631"
     CDS             complement(13946..15178)
                     /gene="murN"
                     /locus_tag="VXE87_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0842220.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSIQMGELLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTRGYPGGEPDWLYYKDLTEL
                     TEKNLLKSFSKKGKPLVKKAETFGIRLKKLRREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDVFGEQAEFLIASLNFSDYMSKLQGEQSKLEEILDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYIMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15183..16403)
                     /gene="murM"
                     /locus_tag="VXE87_000632"
     CDS             complement(15183..16403)
                     /gene="murM"
                     /locus_tag="VXE87_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0842221.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSDWEHEKFG
                     VYREEKLLATASILIRSLPLGYKMFYIPRGPLLDYRDTELLSFVIQSIKSYARSKRAI
                     FVTFDPSICLSQSLINQEKTEYPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKSYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDAGQARVPLAATLTLEFGQTSVNLYAGMDDDFKRYNAPILTWY
                     ETARYTFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16515..17294)
                     /locus_tag="VXE87_000633"
     CDS             complement(16515..17294)
                     /locus_tag="VXE87_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0842222.1"
                     /translation="MAVMKIEYYSQVLDMEWGMNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17363..19024)
                     /locus_tag="VXE87_000634"
     CDS             complement(17363..19024)
                     /locus_tag="VXE87_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0842223.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMSYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19199..21421)
                     /gene="recJ"
                     /locus_tag="VXE87_000635"
     CDS             complement(19199..21421)
                     /gene="recJ"
                     /locus_tag="VXE87_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0842224.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21697..22455
                     /locus_tag="VXE87_000636"
     CDS             21697..22455
                     /locus_tag="VXE87_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0842225.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LSPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEARAQQFLSKIINHESDKVK"
     gene            22495..23259
                     /locus_tag="VXE87_000637"
     CDS             22495..23259
                     /locus_tag="VXE87_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0842226.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDTFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDTLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23272..23661
                     /locus_tag="VXE87_000638"
     CDS             23272..23661
                     /locus_tag="VXE87_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131131.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0842227.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGVFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSLHPDCPHLLQL"
     gene            23866..25056
                     /locus_tag="VXE87_000639"
     CDS             23866..25056
                     /locus_tag="VXE87_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0842228.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25377..26258)
                     /locus_tag="VXE87_000640"
     CDS             complement(25377..26258)
                     /locus_tag="VXE87_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0842229.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26399..27727)
                     /gene="vncS"
                     /locus_tag="VXE87_000641"
     CDS             complement(26399..27727)
                     /gene="vncS"
                     /locus_tag="VXE87_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0842230.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVAQD"
     gene            complement(27724..28380)
                     /gene="vncR"
                     /locus_tag="VXE87_000642"
     CDS             complement(27724..28380)
                     /gene="vncR"
                     /locus_tag="VXE87_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0842231.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28429..28512)
                     /gene="pep27"
                     /locus_tag="VXE87_000643"
     CDS             complement(28429..28512)
                     /gene="pep27"
                     /locus_tag="VXE87_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0842232.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(28692..30071)
                     /gene="vex3"
                     /locus_tag="VXE87_000644"
     CDS             complement(28692..30071)
                     /gene="vex3"
                     /locus_tag="VXE87_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0842233.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30123..30770)
                     /gene="vex2"
                     /locus_tag="VXE87_000645"
     CDS             complement(30123..30770)
                     /gene="vex2"
                     /locus_tag="VXE87_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0842234.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(30783..32060)
                     /locus_tag="VXE87_000646"
     CDS             complement(30783..32060)
                     /locus_tag="VXE87_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842235.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(32416..32586)
                     /locus_tag="VXE87_000647"
                     /pseudo
     CDS             complement(32416..32586)
                     /locus_tag="VXE87_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(32729..33328)
                     /locus_tag="VXE87_000648"
     CDS             complement(32729..33328)
                     /locus_tag="VXE87_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842236.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNTK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(33465..34349)
                     /locus_tag="VXE87_000649"
     CDS             complement(33465..34349)
                     /locus_tag="VXE87_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0842237.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(34353..34739)
                     /locus_tag="VXE87_000650"
     CDS             complement(34353..34739)
                     /locus_tag="VXE87_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0842238.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(34732..36075)
                     /locus_tag="VXE87_000651"
     CDS             complement(34732..36075)
                     /locus_tag="VXE87_000651"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0842239.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(36162..37046)
                     /locus_tag="VXE87_000652"
     CDS             complement(36162..37046)
                     /locus_tag="VXE87_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0842240.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(37058..37675)
                     /gene="cysE"
                     /locus_tag="VXE87_000653"
     CDS             complement(37058..37675)
                     /gene="cysE"
                     /locus_tag="VXE87_000653"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0842241.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(37691..39904)
                     /gene="pnp"
                     /locus_tag="VXE87_000654"
     CDS             complement(37691..39904)
                     /gene="pnp"
                     /locus_tag="VXE87_000654"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0842242.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(40589..41455)
                     /gene="metF"
                     /locus_tag="VXE87_000655"
     CDS             complement(40589..41455)
                     /gene="metF"
                     /locus_tag="VXE87_000655"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0842243.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(41519..43768)
                     /gene="metE"
                     /locus_tag="VXE87_000656"
     CDS             complement(41519..43768)
                     /gene="metE"
                     /locus_tag="VXE87_000656"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0842244.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNSITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(44029..44295)
                     /locus_tag="VXE87_000657"
     CDS             complement(44029..44295)
                     /locus_tag="VXE87_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842245.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            complement(44421..44867)
                     /locus_tag="VXE87_000658"
                     /pseudo
     CDS             complement(44421..44867)
                     /locus_tag="VXE87_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            45023..46024
                     /locus_tag="VXE87_000659"
     CDS             45023..46024
                     /locus_tag="VXE87_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0842246.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSNHRCIFTEITF"
     gene            complement(46092..48497)
                     /locus_tag="VXE87_000660"
     CDS             complement(46092..48497)
                     /locus_tag="VXE87_000660"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0842247.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIEFSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     AHKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(48574..49083)
                     /locus_tag="VXE87_000661"
     CDS             complement(48574..49083)
                     /locus_tag="VXE87_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0842248.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(49083..50129)
                     /gene="pheS"
                     /locus_tag="VXE87_000662"
     CDS             complement(49083..50129)
                     /gene="pheS"
                     /locus_tag="VXE87_000662"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0842249.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHHHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        14280 a        11470 c         9546 g        15191 t
ORIGIN      
        1 cagctcaaaa cactgttttg aggttgtgga tagaactgac gaagtcagta accatacgca
       61 cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga aagctcgatg
      121 gactattcca gattcattcc actagatttc gaaatcgagt aggggataat ctctagcccc
      181 tctcacacca ccgtacgtgc cgttcggcat acggcggttc aactaactgt taacgcatgt
      241 cattcaaggt aataatccaa acacgaaacc agtccacgtt tttcaaggac tggttttgat
      301 atagcacgtt taagtaccga cttctgagct actaattgat agtggtcgcc ccagccagat
      361 accttatccg ctatataggc cttattatca cgttcctgtt cgtagagcca cgatttcgct
      421 atcccttcct ctgacgattc ttatttccag cgtcagactt aaaacggtct atccccagac
      481 cgttttaatc cgctacctca cgatagtcag acttgggaat cgctattggg ttcaccggta
      541 gcaggtgccc accgaggact tacacctcaa atatataata aaatgaaata agaataggac
      601 gaatcgatca ggacagtcaa atcaatttct aacaatgttt tagaagtaga tgtgtactat
      661 tctagtttca atctactata caacatgccc gtcgtacatc aaaaaaagtt gagacatagc
      721 gtcttcaact tttttacatt actttaacta ctgattaaag tgagtttacg tcaactttga
      781 taccaacacc ttgagtagtt gtgatagtca agtttgttac gtaagttcct ttagctgtag
      841 ctggttttgc tttttggatt gtttcgttga aagctttaaa gttttcaacc aatttttcag
      901 cttcaaatga tactttaccg atgattgctt gaacgttacc tgcacggtca gcacggtaag
      961 tgattttacc acctttagac tcttcaactg ctttagcaac atccattgtt acagtaccag
     1021 ttttagggtt tggcatcaag ttacgtggtc caaggacacg tccaagacgt ccaacaagag
     1081 ccatcatatc aggtgtagcg ataactacgt cgaagtccaa ccaaccgtcg ttgattttag
     1141 caacaaggtc atcttcacca acaaagtctg caccagcagc ttttgcttct tcagcttttg
     1201 caccacgtgc gaaaacaaga acacgtgaag ttttaccagt accgtttggc aataccattg
     1261 ctccacggat ttgttggtca gcttttttaa cgtcgatgtt caagttgtaa gcaacttcta
     1321 cagttgcatc aaattttgca aagttagttt cttttgcaag tgctacagct tcttctacac
     1381 tgtatgcttt tgtgctgtcg attttctcaa gagcagcacg aagttgtttg ctttttttag
     1441 ccattttcta ttctccttgt aagtggttca atcgattttc atctcccacg tcacttctcg
     1501 aaatgatgaa gtcttgcggg ttttcagtct actatttttc tcttcctacg gccttaagct
     1561 cccttgctgt acccaagtac aagcctcagt cacttgccta gtatgaaaag caactaatag
     1621 actgctgtga gattttctac tgtgttattg attagtcaac aacagtgaat cccatagaac
     1681 gagcagtacc ttcgatcata cgcattgcag actctacgtt tgctgcgttc aaatctggca
     1741 tcttagtttc tgcaatttct tgtacttgtg cacgagtaac tgtagcaact ttagttttat
     1801 taggtgtacc tgatcctttt tcaacacctg cagctttttt caaaagaaca gcagctggtg
     1861 gtgttttcgt aacgaaagta aatgatttat cttcgtaaac tgagataaca actggaatga
     1921 tcataccagc ttggtcagct gtacgagcgt tgaactcttt tgtgaatccc atgatgttga
     1981 taccagcttg accaagagca ggtccaaccg gtggagctgg tgtagcttta ccagcaggga
     2041 tttgcaattt tacaagtttt tcgacttttt tagccatttt taaatcctcc tttgtggttt
     2101 tggcggtaat tagagatttt tacctcccac aagtatgttt ttcacatacc catccattat
     2161 acactattta tctggaattg caagagaaaa gtttattttt tatactcaat gaaaatcaaa
     2221 gagcaaacta ggaagctagc cgcaggctgc tcaaaataca gctttgaggt tgcagataaa
     2281 actgacgaag tcagctcaaa acactgtttt gaggttgtga atagaaccga cgcagtcagt
     2341 aggtaaggcg acgctgacgt ggtctgaaga gattttcgaa gagtattaat cgacgtagtc
     2401 tccgccttca aagccatagt attcttccaa actgagaccg cttgcagcaa tttctttagc
     2461 ttcttttcct acataacgca ggtgccattc ctcagccata tagcctgttt ccttttcctt
     2521 gcctttgaga taacggacaa caaagccata atcagctgca tggtccaaga gccattgggc
     2581 tgctttttct tctgtcacca aatcaccatc agtcccaatc acatcaaagg ccaagcctgt
     2641 ctggtgttcg ctatagccag gacgggcaga gtaacggtca gctgctgcct ttccatcttg
     2701 gttgacataa tcttgataga gcttggtctg agtttcataa cttctaaaac cactgtaatg
     2761 atcactaata gggaaacctg cctcttgcat cgctttgatg agtttgacca actcagcctt
     2821 ggctgttgga ttttccccgg gattatagtc tttcgacaaa ggataatgtt tattggctac
     2881 gatgatttcg tcgtattttc cttggatgct gtagtaatca cctttattga ccacttctgc
     2941 ttttttctgg gcagcccctt gagacttact gccgactgtc ccatcagctt tggctgtctg
     3001 ttctgtctta gctgtgccat cttcattttt tgctttttct tgtgaacaag ctgctagact
     3061 caaggctagc aaggctgtca cgacaaggta tcttttcttc atttctactc ctttatttct
     3121 aatagtttat ctacttctga tgataaacgt ttgactaatc ttttgatctc atccggtttt
     3181 gcttggcagg tttctgctgt catttcttca aaaggaaccc accaaactgg accacgtccc
     3241 ttgagaccgt gaccattcat atcacctgtc cgtcgtggaa acagatgcca atgaagatgg
     3301 gcatcgccat ttcctaaaag ttcaatattc attttctcag cagtaaaggc cttagcaact
     3361 gcctcttgga ttagactcat ttcttcgaga aaacgtagtc ttgtttcctt ttctaaatgg
     3421 tgcaattccg tgacgtgttc cttggctaga aagagactat agcctgcaaa atactggtga
     3481 tctccaatca caagatagcc tgtttccaac tctttgacaa aatagggatt ttctcccttc
     3541 ttgatgagct caattctctg gcatataaga cacatattag tctaccaacg cgctcttaat
     3601 gtaagcatca accatacgct ctgttgcgac caccgagtca atatgagtac gctcataaga
     3661 atgactagac tcgatacccg cgccaaggag ggcgtgtttg acctctgccc ctgcggacat
     3721 ggccgctgaa gcatccgaac cataaaatgg atagatgtcc agcttaaaag gaatattttg
     3781 ctctttcgcc aaggtcacca agtgttgacg gaagtcatag tgataagggc ctgaggcatc
     3841 cttgacacag atagacactg tgtactcatc tgtttgctgg ccatcgccca tagctcccat
     3901 atcaacagcc agatattcga ctacctgagc aggaatgtta gaattagcac catgtcctac
     3961 ttcttcaaaa actgaaaaag caaaatgagt tgttactggc aattcaatct tctctttctt
     4021 ataaatacga agcaggttga gcaaaatcgc tgcgctgacc ttatcatcca aatgacgaga
     4081 cttgataaaa cctgtatcag tcacaacagt tcgtggatcg aagctgataa aatcaccgac
     4141 ctcaatccca agagcacgag tttctttttc attgcttact tttacatcca aacgcacttc
     4201 catattgtcc tgcgtgcgtt ctgcagttcc tgcatccttg tagacatggc aagaagtttg
     4261 gtggatgagg atggttcctg ataccttttg acctgtgcta gccacatgaa cggtacagtt
     4321 ttcaccttca atcatgttcc aaggaaaacc accgatacgg tccaatttaa gacgaccatc
     4381 tggtttgaca gcacgaacaa tagcacccag cgtgtccaca tgggcagtca catagcgatg
     4441 ttgctcatca ttttgacctt tgatggtcac attgacacca cccttggctg tgcgaactgg
     4501 ctggtaacca aaaccttcta gagtcttgac taaataattc gaaatttcac gagtgaagcc
     4561 cgttggcgat gcgatggctg tcagttcttt gatatattct actgtttgat tcatttcttc
     4621 acctctttcg ctacctatta taacacattt atcatcggat aaaaaaagaa aatcactcct
     4681 gtagacttgg ctacaaaagt gatctaagtg attattccat ttcaaaaaca tcgctttctt
     4741 gcttgtttgg tagaaccaat gagagcaaga ttccaacaat ggctggcacc aaccatggga
     4801 gagatgcctt ggcaaaagga agaacgctaa caagatttgc aagaaactca accttaaacg
     4861 agcttcctag tacgcttgca atggcaataa ctgtaaccac agcaattgtc aactgcatac
     4921 ctggttttga aagggcaaca aatttgttga caatgacaat cataacgata gcaatcgtga
     4981 ttgggtacaa gataaccagt actggaattg agtacttgat aatcgcatca agacccaaat
     5041 tggcaatagc aaatccaatc aaggtaaagg ctgtcgcata aaccttgtag ctgatttgtg
     5101 ggaagcgctc attaaagaac tcagctgttg acacaatcaa accaacagtc gttgtgaagc
     5161 aggttacggt aaccatagct gcaaggaaga gttgagctgt tgagccaaag atttcttgag
     5221 tggcttgtga caagatgtaa acacctggtg ttccaccctt catcgcttca gctggtactg
     5281 ggaaatgatt tccaagaaaa cctaaaccga tgtaaagagc gctgaaggca agggcaacaa
     5341 cgataccaac aacccaaata gttgaaatgt attctttctt acttgaaaat ccaagttgtt
     5401 tcaaggtttg aactgcgatt acgctaaagg ccactgaggc aagggcgtcc aaggtattgt
     5461 aaccttctag gaaacctgta ccaaaggcag aagcttgata agcagctgaa gcagcttgag
     5521 gacttgttcc accatatttg atagctccca gaacgaccaa gataacaatc aaaattgcaa
     5581 agactggcgt taaaatacgt ccaatgcggt ctaagatttt tgatggatta agcgaaatca
     5641 aataggctgc cgcaaaatac agaaccgtaa atacaatcaa gccaagtcct ttatttgcat
     5701 ccgacaaaag ggggctaatc cctacttcgt aagctgttgt agcagtacgt ggggtagcaa
     5761 agaatggacc gattgacaag taaagaactg agaggtaaag agtcgcaaac caaggcgcta
     5821 tcttcgttga aatctcgtag atatatcctt taggatttag cgttccaata ataagggtca
     5881 agacggcgat accaacgcct gaaaagacaa aacctgcgat ggcaggaaga aaatgttctc
     5941 cagatagagc acctagagaa ggcggaaaaa tcaagttccc cgcaccaaaa aatattccaa
     6001 acaggagcaa acctgttagg gtaccttttt tagccataaa aatctccttc atatttataa
     6061 aatactgacc tagtatacca cgattaggag tctgaaaaaa gcatcacgag gcaaatatta
     6121 aatgttttca attttcttaa aaataagaat tatctaaaaa taaaactctc ctacccagtc
     6181 cacaccaagt aggagaaatg caaaatttta aagttcttca aaggctaaca tgccaccctg
     6241 gacattgata acattataac cttgttctaa taggaattgg caagcacgcg ccgatctcat
     6301 tccagatttg caaataatat aatgcaagcg atctttgtcc aattaatcat aactatcagc
     6361 caattgacta agcggtaggt tgtgggcacc ttctaaatga agagctgcaa actcatccac
     6421 ttctctcaca tccactaaag aaagctggtc gttttggtaa agctggtaaa atgcgtcaaa
     6481 ggctatttct ttcattcttt ttcttctaat actcttcgaa aatctcttca aaccacgtca
     6541 gcgtcgcctt accgtgcgta tgttaccgac ttcgtcagtt ttatctgcaa cttcaaagct
     6601 gtactttgag caacctgcgg ctagcttcct agtttgctct ttgattttca ttgactataa
     6661 aatggtttta attctttttt tcaaatctgg caccacttct gactcaaacc aaggattttt
     6721 ggccatccag atttgatttc gcggcgaggg gtgaactagt ggaaaatagg ttggtaagta
     6781 gttctggtaa tgttttaccc gttctgtcac cttgccactg attttctcct gcaaatagta
     6841 ggcttgggca tattggccaa tcaagagggt caattgaata tctggtaatt cttgcaagag
     6901 ctgcggatgc catttttcag caaagccagt tctcggtggc agatcacctg actttccatg
     6961 ccctggaaag tagaaatcca taggcaaaac agcaaaatat cctgaattgt aaaaggtatc
     7021 ttcatccaca cctagccagt ctctcaggcg gtcaccactc ttatctttcc agtaaaggcc
     7081 tgcttcttgg gttttaagac caggcgcttg accgatgata ttgatgcgag cagtctttgg
     7141 cgctgcaaag agaggctcaa tgccacgctc tgtatagctg gcattttgtg gatctgacat
     7201 aatagcctgc ttgattcttt caatttgaga catctacttt ccctccaaaa agaagtctaa
     7261 gcatacaatc tcagacttct atcgttttat ttgatcaatt cgtaaatagc ttcggcatag
     7321 attgctgctg ctcggaagag atcatccaag gcgataaatt cattggcttg gtgcatggtg
     7381 tcaattgagt ctgggaacat ggcaccgtag gcaactccgc gttcgagcaa acgaccaaag
     7441 gttccaccac cgataacttg ctcgtgacct ttaagtccag tttgtttttc atagacattc
     7501 aacaaggttt gcacaagtgg atcttccatt ggcacatagt gaggggtatg accgtgctca
     7561 gaaaggctaa cagaagcaac tggcaagttt tctaggattg acttgatttg ttctggactt
     7621 gttccttttg gatatcggat gttaagggca atggtattat cagcgcttgt ttcatcaaag
     7681 cggaagacac cggcattcat agaaagggca cccatctttt catccacatg ggcaatcttg
     7741 agattttcac cctcatggtc gttcaagaga atcttaccag cgatgtcaag gtagtctttg
     7801 gctggatcag caaagtcaaa ctgactgagg aagagggcta ggtaagtcgc accattgaca
     7861 cctgaagcag gcatagcacc atgggctgat ttaccaataa tcgtcacctt gtattggcca
     7921 gcttcttctt ggagttctcc tctgagcttg tgttctgcaa caaaggcatc tagtttagct
     7981 tgcaagtcag ccaggtcacc tgaaacgact gctgttgctg attctggtac catgttttca
     8041 cgtaaaccac ctgtaaagct gtgaagacgg gctgcacctg tattttctcc tgcaaagtgg
     8101 aggtattccg tgatatttcc tttttcacca ttgatgatag ggaattcagc gtctggagag
     8161 aaaccgaagt ctggtttggc aagtcctacg tgctcaaagt agtagtccat gtctgcccag
     8221 cctgattctt cgtctgttcc gacaataaag cgaactttct tagaagttgg aagacccaat
     8281 tctttgatga ttttcaagcc atagtaacaa gctgttgtag gacccttatc gtctgaagca
     8341 ccacgcgcat aaaggcgacc gtctttgata gtcggtgtgt aagggtctgt gtcccaaccg
     8401 ctaccagctg gcaccacgtc catgtgagca aagattccga gaacttcttc tccatcacca
     8461 aactcgaaat gtcctgcgta gttatcgaca ttcttagttg ggtagccatc gcggtctgcg
     8521 atttcaagga atttttccaa ggcttttact ggaccaggcc caaatggatg ttcagcatca
     8581 accttgctgt catcacgttc tgagttgatt tccaaaaggc taaacaagtc agccaagagg
     8641 tcttctttgc gtttttctac ttctgctgta aaatcaatta ctgtcatttt tttcttcttt
     8701 ctatcttttc tcgatgattt catctactgg caagcggtaa cttggttcca atttttcgtc
     8761 tgtataaccc actgtgatca agagttctgg gcggaaacgg tcttcgatat ccaaaacttc
     8821 gttgactttt gatttgtcaa aaccaagaat cagatttgat ccgattcctt ggtctgtaag
     8881 agccaaaacc aagttcatag caaccaagcc tgcattgagg gctaggtagt cgctgacttg
     8941 ctgttcattg tagcgtgcaa attcagctgg caaatttttc atgaagtatt gaagttgttc
     9001 ttcagaaaag ttattagcac caccaacacg agcaatctta cgagcacgtt tagccaaatc
     9061 tgtgtctgta aacaaggcaa tagttacagg cgctgatgat acctgttcaa agtttgaacc
     9121 gtaagccaat tttgctagtt cggcattttt ctcacgtacc accacaaatt tccaaggctg
     9181 gctgttgtgg gcgcttggtg ccaaggttgc aatttcgata gccgtacgca catcttttgg
     9241 atcaacaggc ttgtcagtga aatgcttagt cgcatgacgt tttttgttta attcaagaaa
     9301 tttcataatc gatttccttt tctaattcta ctgcttccat tctaccatat tttgaaagag
     9361 cttgcagata ttttccatga ttaagttttt ttatcacagc cataaaagat atatattggt
     9421 gcatcaagac agtttctgat aaactagcaa gtactttaca tttgaatgga gacattatga
     9481 aaaaatttag ccttttacta gctatcctac catttttggt tgcctgtggg aatcaagcca
     9541 cacccaaagc aaccaactct caaaagacaa tcgtcgttgc tacagctggt gatgtgccac
     9601 catttgacta cgaagacaag ggcaatctga ccggctttga tattgaagtt ctaaaagcag
     9661 tagatgaaaa actaagcgac tacgagattc aattccaaag aactgcttgg gaaagtatct
     9721 tcccaggact tgattctggt cactatcagg ctgcagccaa taacttgagt tatacaaaag
     9781 aacgtgctga aaaatacctc tactcacttc caatttcgaa caatcccctc gtccttgtca
     9841 gcaacaagaa aaatcctttg acttctcttg accaaatcgc tggtaaaaca acgcaagagg
     9901 ataccggaac atcaaacgct caattcatca ataactggaa tcagaaacac actgacaatc
     9961 ccgctacgat tgatttttct ggcgaggata tcggtaaacg aatcctagac cttgctaacg
    10021 gcgaatttga tttcctcgtt tttgacaagg tatccgttca aaagattatc aaggaccgtg
    10081 gcttagacct ctcagtcgtt gatttacctt ctgccgatag tcccagcaat tatatcattt
    10141 tctcaagcga ccaaaaagag tttaaagaac aatttgataa agcgctcaaa gaactctatc
    10201 aagacggaac actcgaaaaa ctcagcaata cctatctagg tggttcttac ctcccagatc
    10261 aatctcagtt acaataatac tcttcgaaaa tctcttcaaa ccacgtcagc tttatctgca
    10321 acctcaaagc tgtgctttga gcaacctgcg actagcttcc tagtttgctc tttgattttc
    10381 attgagtata agatatacta aaagcgattg gaccagccaa tcgtttttag tttgcattgg
    10441 ttattttagg aaactcttac aaaaaatcaa aaaaattctt cacatcctct acatacccat
    10501 gcttttctat taagcttgct aataattcca gattgtgtcc ctgatagtta tcttcacgac
    10561 gtaattcttc atacatttcg ataaagggaa gccccttgga cttggccaat tccaactcag
    10621 cttcgtaatc ataagcgact ttacgaaata ggatatttac caattcccca tcttcaacct
    10681 ctatcacggc atactgggca cggtgatttt ttaacgcttc ccaattaaaa tagggcatgc
    10741 caatcgaccc tggattgatg atttgttgcc cttgactgcc ataacgaagc aactgcttgt
    10801 gaacatgacc atagactgcc acgtcaactt catcatctag gagttggtca aatttctctg
    10861 tatcattctc aaccagtaga tccccaccat agtttttatc aggtaaatta tgagagatag
    10921 aaaagcgcag cccctcaact tctttctttt ccagcatagg caagcttcgt agccagacaa
    10981 tcgttacagg atccattcgc tccatcaaaa actgggtcat gcgaattaac tggatttctt
    11041 gcggattttc caaaccgtat tgcccatcca agacctccag gacacaatca tcccaattgc
    11101 ctcgaacact ggctgtgata ggaaggtcct ttagcagggc gactaagtca tttgcgcctg
    11161 gaccaggaag aaaaatatct cccagaagcc agtattcact gactccttga tttttagcat
    11221 ctgcaatcac tgcttctagg gccgtcgcat tgccatgaat atctgataaa attgcgattt
    11281 tatgattcat tgtgttctcc ttctgtttgg taatctactt gtttttccgc cacttgaggc
    11341 aaggcttctg cctcctgcgg gttcaacttc ctctgcacag cttctgcaac ggctctaggt
    11401 actccaactt cgacaatctc atccacactg gcttccttga ttttggtcag agacttgaaa
    11461 tgcttcatga gattctgctt acgtttaggc cccagccctt caattccatc tagttgtgat
    11521 gaaaaggaat ttttagagcg cagttggcga tggaaagtga tagcaaagcg gtgcacctca
    11581 tcttgaatgc gttggaggag gaaaaattcc tgagaattgc gagacaagtc caccacttcc
    11641 agcggatctc caaagagcaa ttcatgggtt tgatgcttgt catttttttg cagacctgca
    11701 atggggatat ccaagcctag ttcatcttgg atgacttgct tggcgatatt gacttgacct
    11761 tgtcccccat caatgacaat caaatctggc ggagtcaaac cgtcacgctg tactcgacca
    11821 taacgcctgc gaatgacttc tctcatactg gcatagtcgt ctggtccaac aaccgtcttg
    11881 attttgtatt tacggtaatc ttttttactg ggtttaccat tgacaaagac caccatagct
    11941 gaaacagggc tagttcccat gatgttggag ttatcgaagg actcgatgcg aactggagtc
    12001 ggaatttgga gcaagcgtcc tagattttca atagccccct gtgtcttttc gacagatttt
    12061 tctagcagat tgaacttctg ctctaggcta acacgggcat tttttatggc tagattgacc
    12121 agctgttttt tctctccacg ttggggtttg agaatcttgg tatctaccaa gaccttgaca
    12181 gcttcttcgt caatatcctg cggaatcagt acctcattgg gaactaggtg agatttttct
    12241 tgataaaatt gtcccacata ggtcaaaaaa tcttcatccg gatcattgta gtaggggaag
    12301 aggttaacat ctcgctcaat gagcttaccc tgacggacaa agaaaacctg aacacacatc
    12361 cagcccttgt ccacatagta gccaaataca tcccgatttt ggagatcctt ggccataacc
    12421 cgttgcttgg tccgaagcgt tccaatggcc tgaattaggt cacggtattc cgctgcacgt
    12481 tcaaattcca tagtctgggc tgccgctgcc attttgccct tgaggtcatc aatgattttg
    12541 tcatcctgcc cttttagaaa atcagaaacc tcctgagcca tagacttgaa ataggcctca
    12601 tccttcttac agatagtgtg ggccatgcat tggccgatat ggtagtaaaa acagacctta
    12661 gacggtggat tggtacactt acgaaaaggg aaaatacgat ccagtaaccg cttgatttca
    12721 ttggctgccc ccacatctgg ataaggtcca aagtagagac ctccgtcctt cttgacctga
    12781 cgggtgataa tcaaacgagg atagcgttca ttggtaatct tgatgaaagg ataggactta
    12841 tcatccttga gcatgatatt gtacttgggc ttattttcct tgattagatt gatttctagg
    12901 agaagtgcct caatattgga ctccgtaacg ataaattcaa aatccacaat ttcagacacc
    12961 aaggcctctg ttttagtatc atgacttcca cggaaatagg accgcacgcg gttacgcaga
    13021 ttttttgcct ttcctacata gataatggtg ccgtttttat ccttgtgaat gtagcaacca
    13081 gggctggtcg gcaagagctc tagttttgat ttaatcaagt tgttcataat tccattatag
    13141 caaaaaagta gggaaagata gtcccctact cattggtctc atataatttt cgaagtcttt
    13201 caacatcctc ttcctgaata ccataaaagg aacccgcagg ttgcatcaca gacttctcat
    13261 ctgtatggtc caagccaatc gcatgcccca actcatgttc tgccgtatgg acaaggcgtt
    13321 cataggaata gccatagtct ggattggaca aataataatg attcaaccgc accgttacag
    13381 acaagaattg ccccgttaag agattggtct gactttccgc ctctcctgcc acaggagtac
    13441 ctccgtcatt cacctccgta gccaagatat ctgccttgct ggactcggtg acaatttcaa
    13501 agttaaaagc acccgtttga ttccaattct gaatcgcttc tacataagct tcttgaaagt
    13561 gtgaatccat ctggggatcc aagtaaatac gagcagaagc ctgtggccat cttccttcag
    13621 aatgctggtg gctatctgtc tgattcaact taggcagttg ccctgttttt tcccattggt
    13681 cgatactttg ttgaccaatt tttactgacc gttctgcttg ctttagcgct tcttgaaaat
    13741 ctccgttcaa ataccagaga agtccgaaag ccagcgcaca taagagcaca actaaccaaa
    13801 ccaggcgcca aaacaaacgc cagacaaaag aaaagaaacc tcctatcaaa cgaaaaagcc
    13861 agcgcatatc cttccacctt tctagcaaat aaaaattatt ttactaaaac aagctgaaag
    13921 aaagctaaat actgactttt tcatcttaac gtcctactat ttttttgagt aactggatag
    13981 ctttgtattt taaaggcgat ggatggtaac ggaaagtacc tgctttgcgt acaatatagc
    14041 cattaaaatt ctgtttgaaa cgcaaaacac catcactacc atcaaaaatc ccttgaatac
    14101 ctaggaagtt gtatttaggt attccacgtt ttatactttc caacataata tatttttgaa
    14161 gcagtgcagg ggcatagaat ttattaaact cagtgtagga accactaaag agataagtcg
    14221 tttcctgagg catataaaca aataaactcc cagctaaaac aatatcttct tccccatatt
    14281 tttcaatcaa gtctcgcgct tctgcttttc gaacttcaaa cgtttcaaat tggctagaat
    14341 attctctcag ttgattttgt tttttctcag aatgaggatt tttactcaaa tcaagtcgca
    14401 acttgtccaa gatttcttct agtttacttt gttcaccttg caatttgctc atatagtccg
    14461 aaaaatttaa gcttgctatg agaaactccg cttgttctcc aaaaacatca taaaaatgct
    14521 cataatattc taaactttta tcactatatt ctctacgttc agaggtttct tttgtgatat
    14581 tcttaaaaat cgatagttct tcacgtctta actttttcaa cctaatgcca aaggtttcag
    14641 cctttttcac caagggttta ccttttttgc taaaactttt aagcaaattc ttttcagtta
    14701 attcagtcaa atctttatag tataaccaat ctggttctcc acctggataa cctcttgtca
    14761 agccatcaaa ttgataccct aaatcagtta aaccttgaat gatacttttt ttctcagcat
    14821 ctattggatt accttggcta tcaaaagttt gataagtttc ataaggtttt acaagcaact
    14881 ctaatacacc attttgcttg gcatattctt ttaactccgc ataaaaaact ggaagagcat
    14941 cttgttgggt ataaatcggc cccgaattga gctccatatg cagaccaccc agcatgggca
    15001 agctataaac cagagctgca acttgaatct ctccttcttg tttcaaagca agataaacaa
    15061 ttcgagcccc tcttttttct aataattccc ccatctgaat cgactgcata aaggaacgag
    15121 aagaaacctg atcagaataa gtctgaaact cttctttcgt gagtgttgtt agtgccatat
    15181 acttactttc tatgtttttt tcttaatgtt ttacggaaat caagagcaag tcttaacaga
    15241 ggatagagag gatgagtggg cattgtaaat tcacccaagt attcttcaat cgttggatta
    15301 aatttttcct taaaatgata aagtccacca ttgagagagt tttcaacacc acctaaattt
    15361 tgccagacca tacctcgctc aaaggtatag cgagccgttt cataccaagt taaaatcgga
    15421 gcattgtaac gtttaaaatc atcatccata ccagcatata gattgacaga agtttggccg
    15481 aattctaaag tcaaggtagc cgctaaagga actctcgctt gacctgcatc tatatattcc
    15541 tgcaagaagg tcaattcctc taacaaacgt tccttttcct tcttctgcgc ttctactttt
    15601 gaagttcgag tcgactcagt aaaggtctct tccaaagctc tgtttttcgc taactgttct
    15661 tctaattctt gcgaacgttt agagacatcc aaggttgcca aggtgatata ggacttgtcc
    15721 ttaaaattat ctaacaactt tttataatag gcttcattcc tcaaatgaat ctctttccgc
    15781 ttctcggttt ttttcatcaa aaaggaaaag gactccaata attcagttcc accaaattga
    15841 atctctacac ccttattccg tgctgttcga atagcctgtt ttgttgactt ggaaagttta
    15901 tcttcttcaa aattttcctt gtatattttc gcctgaatac gaggttgaat ggtgtctccc
    15961 atttcctctg tttttcctga ccaccttact cccatttgtt gcaaactatc aataatagcc
    16021 agattttcag gatattctgt cttttcctga ttgattaaac tttgagacag gcaaatactt
    16081 ggatcaaaag tcacaaaaat agctctctta ctgcgagcat aagacttaat ggactgaatg
    16141 acaaaactca agagttccgt atccctataa tccaataaag gtcctcttgg gatgtaaaac
    16201 attttatagc ctagcggaag acttctaatc aaaatactag ctgtcgccaa taatttttct
    16261 tccctgtaga caccaaactt ctcatgttcc caatcagact taacttcctc ccaagcacta
    16321 ctttgtaata cattggctaa ttcatgttct ttgacaaact gatcatattc taatgtggga
    16381 atgccaattt gataacggta catttcctac tctctttcct ccagtatttt attactattc
    16441 tactactttc gtttgaaaag tctagtgaaa acatatttta ttttagttct actcccccta
    16501 tgctgaagtt caaactaagt cagtctctct tctaatttga aatcaattgg tagagttgtt
    16561 aaaaaaactt ccaattgttt ttcccagtag taccactcgt gagttccagc gctatggcta
    16621 taggtcacat caaaacctag ttttttgaga tttttcactg cgagattatt ggcttcgtac
    16681 aagaaatcct gttcgccaca ccacgcccaa agtttggtct ttttatccga ttttttagcc
    16741 agactttcaa gagaataggg actagttgtc cagtctctaa tctctccaaa aacacctctc
    16801 cagtaggctg gacttcccag attttgactt tcaggagaaa agttttgaaa gctgagggca
    16861 cctgaaaaac tagctgcatg agaaaaacga tttgtcgcaa gagccagttt gaaacagccg
    16921 tagcctccca tagaaagacc agctataaag gtcttttcac gcttgctagt catattaggg
    16981 aagaagcgtt tcagaacctg tggcaattcc tctgctagag ccgtgtagta gtcaaaacca
    17041 tactgggtat cggtgtacca accattgctg gtattgggca taacaacgat gagattagtt
    17101 cctcgaagca agcgttctac attggtccgc ttaagccaac tattatgatt tccagacatc
    17161 ccgtgcaaaa ggtacaagac gggaatatct tcacactctg gttcttccac tcgattggca
    17221 tcagggtaga ggacattcat cccccactcc atatccaata cttgtgagta atactcgatt
    17281 ttcattactg ccatgatttt ctccttctat ttttctataa gaaaaagccg aaactcgact
    17341 ttctctctgt ttatttcaac gattattttg cttccatgac tactggtaaa atagctggac
    17401 gacgcttggt ttggtcaaag agatacttgg tcaaattatc tcgaaccttc cctttaagat
    17461 ctgcccagtc aaagtcatct ccttgaagat aatcttctac cgtttggtta atcaattctg
    17521 aactttcacg gagaatatcg cgactcttct tgagataaac aaatccacgc gtgtgaacac
    17581 gagctctagc cacaattttc ttctcacgac ggttgactgt aatagccacg atgaaaattc
    17641 catcctctga caagacctta cggtcacgaa gaacaacatt tccaacatca ccaatggcat
    17701 tcccatcaat caagatatct cctgctgaaa ccgatccagc tggaacgaag tctccattct
    17761 cgtaagacat ggtcgtcccc tttttaggaa tgaagatgcg ttctggcaac atcccaactg
    17821 ccatggcagc cttagcgtga gcatccaact cacgatactc cccttggaca gggaagaggt
    17881 acttaggttg caaaagattg atcatcagct gcaaatcacg cacatttccg tgccctgata
    17941 catgtaaact ttgggtaatc aatttgacaa ccccacctgc ctgataaatc atattttcca
    18001 cacgcgcaac aaaggcttct ttagcaatag acggagccgt agcaatatag actaggtccc
    18061 catccttgat ttctacataa cgatggcgac caatcgacat cttacgaagt ccattgatag
    18121 gctcacccat acgacctgtc tcaagaataa tcaactcatg gtcttcaaag cgagacatat
    18181 ctttaggctt aatcaaaaga atttcgttgg ctaaagacaa cttcttaaga cgaatcgctg
    18241 tgcggacgat attttcaata tcaaatcctg tcaagacgat acgtcgacct gttttatccg
    18301 cagcgtcaaa aatctgctga atacgagaaa gattactgga aacagctgca acgatgatac
    18361 gaccttccca gtcagcaata gtttgggtaa tttcatccct aacttcactt tcactagcca
    18421 cctgaatatt gctgtctgca ttggccgaat cactgaggag agccaggacg ccgtcacgac
    18481 caatctctgc caaacgagca aaatcagttg cataagattc actagccgtt tggtcaaatt
    18541 tgaagtcacc tgtataaacg atgcttcctt ccgatgtctt caagacaatt cccagactct
    18601 ctggaacgga gtaagtcgta gggaagaagg aaaccactgt cccaccaaaa tcaatctccg
    18661 tattctcatc aatgacatgg aaatcattaa atttcttaac ggcatcattt cctttgacaa
    18721 agagctttgc caactcaatg gtcaactcag acccaaatac aggaacttta gcctctgcca
    18781 agagatacgg tagagcacca atggcatccg catgcccgtg ggtcaagaaa accccagcaa
    18841 tacggtcgct attttcaaaa aggtaatcca tgtttggaat caccacatcg acccctaatt
    18901 gttcattttc aggatatttt aaccctacat tcaaaacaaa aatggactct ccaatttcag
    18961 caatgtacat attttttcca ttctcacgca caccaccaag tgttgttaaa ctgatattac
    19021 tcatttttcc tccaaaatct tagtttatct tgattatagg gcaattctac cctcttattc
    19081 taaaagttct gatactttca gccgaatctt ttcctaccat tataccattt ttttgatgat
    19141 tttcaaaatg aaggtctgtt ttcaaaaaag agttgatttc ccaactcttt cctaacttct
    19201 actctttttc catcaaaaaa tcataaattt cttgcaccgt acccagcgcc atcatttctt
    19261 ggtctttaac ggtttgtttg agattttggt aaatttgact ttctcctatc tcccgctttg
    19321 gcgcctcttt attgactgtc atcacaccat cttttatcgt cacaaagcct agttcttcaa
    19381 atacttgaat catcttgacc agcaagattt gttgaatatt aagatatgca gccaaatctt
    19441 tcagcttgta gcgaatatca aactctggga actggtaaat agtcttgtac aatttggcaa
    19501 actgatctct agtcccataa cctgtcagat aataagcctt gtcaatatca tttttgaaat
    19561 agacagcaga gaaatgctgt tcctgaaaaa tggtcttcag ctgagtaata tcctctggaa
    19621 tgttttttac gacaacagct tcactagccg caagatttgg cagttctcca ggaaaatcca
    19681 agactggaac accttctggc aagactgcat tttttccacg aatgttaaaa agttgaacac
    19741 cttccactcg cgcatccacc atcatcaact ggagggcagt ttggccattc cattggttga
    19801 cagacaattt aaccgctaac tctagattct tggtttgaga aaactctgtc gcccatctgc
    19861 cttgaccaaa ggctaccact tcaaaactcg cctcaccctt ggaaattttc agctttagat
    19921 gggcattacc tgcccccata gtacgagcac tttcgacctg aaaattcttg atataaaaaa
    19981 taggtttctg attatccatt ccaaaaggag ctaaacgttc aaaacttttg accgtttcca
    20041 agctaagtgc ctccaaatcc aactcttcat ctaggtttaa cttattcttg ccaccagcat
    20101 ctgcaccttt ttcacgaaca taatcttcca aaacctgaga taaatctgag agttgctcaa
    20161 cttccagcgt catacccgct gcacctgcat gacctccaaa ggcgatgaag aggtctcgat
    20221 agggatccag agcttcaaaa atatcgaccg cttccacact acgagcactg cccttggcac
    20281 gaccgtcttc tatattaaga acaatgactg tctgtcccaa ttcttccaat aaacgaccag
    20341 ccacgattcc tagaacccca ggattccagc cttccttggc caagacctga accttcttct
    20401 caggatccac catggtcttg gcttcttcat agatagactg aacgatttcc ttgcgctctt
    20461 cgtttttctg gtgaatcata agggcaatct catgcgcttc ctcatcatca aatccagtca
    20521 acaaatcaat ggcaggattg ggatcatcca agcggcccaa ggcattcaaa cgaggagcaa
    20581 tctggaaacc aaccgtttct tctgttactt cgttagcagc aatcccagcc atgtccagca
    20641 tttcttgcag accaatgcgc tgggtatgac ccaacatttc cagaccatat tgaactaaga
    20701 tacgattttc atccgtcaga ctcaccatat ctgcaatagt tccaatagcg accaaatcaa
    20761 gcaattccac ttgcacttct tctaacaggg cacaagccaa cttgaaagca actccacaac
    20821 cagccaaata tttaaaagga taatccgcat ctggatgttc aggatggaca atagcataag
    20881 catctggcag ggtttcaggc atggaatgat ggtctgtcac aatgacatct actcccatag
    20941 actgagccaa tgcaatagcc tcatgaccag caaccccatt gtccaccgtc acaatcaagg
    21001 aaattccttc ttgctcgata aagtatttat aaacactagc attagggcca tagccatcgg
    21061 taaaacgatt tggcaggtaa actcggcact ccgcaccaag ttgttccaaa ctttccttca
    21121 caatagaagc cgaagtcatg ccatccgcat catagtctcc ataaacgaga atattttccc
    21181 cttcttcaat agcctgacga atccgctcca ctgccttgtc catatcatgg agcagataag
    21241 catcatgtaa gtcctccaag gaaggttcta aaaacttctt cagactttct tggtcctgaa
    21301 tccctctctc aaacaataac cgagccacct caggacccag tccagccttc ttggctatct
    21361 ttgtaaaatc cgcatcttct acctgcaggg caaactgcca ttcataagta ggtgttatca
    21421 aaaagacatc cactctttct aagaattcta ttgcttcatt ataacatgat ttagacgttt
    21481 tctctatcca gattgctttt ttataacatt ttatagtata ttgaaactag aatagtacac
    21541 ctctacttct aaaatattgt tagaaatcga tttgactgtc ccgatcgatt tttcctgttc
    21601 ttatttcact atagtgaatt tttcagatat ggtttgacaa gaacattctt ttattgtaga
    21661 atcgtgttat aaaacctaac ataaaggaga tctctcatgg ctttagtaga atttaaaaac
    21721 gtcgaaaaat attacggaga ctaccacgca ctccgcaaca tcaatctccg ttttgaaaaa
    21781 ggacaagttg ttgtcctgct tggaccttct ggctctggga agtccactct tatccgtacg
    21841 atcaatggtt tagaggctgt tgacaaagga agtctcctag tcaatgggca ccaagttgct
    21901 ggtgccagcc agaaagattt ggtacctctt cgcaaggaag tcggcatggt ttttcaacat
    21961 tttaaccttt atccacacaa aacggtgtta gaaaatgtga cactttcgcc cattaaagtt
    22021 ctaggaattg ataaaaaaga agctgaaaaa accgcccaaa aatatctgga atttgtaaat
    22081 atgtgggaca agaaagattc ctatcccgcc atgctatctg gtggacaaaa acagcggatc
    22141 gccatcgctc gtggtcttgc tatgcatccg gaactcctcc tctttgatga accaacatct
    22201 gctcttgatc ctgagactat cggagatgtt ctagcagtta tgcagaaact ggcgcatgat
    22261 gggatgaaca tgatcatcgt tacccacgaa atgggctttg ctcgagaggt tgcggaccgc
    22321 attatcttta tggccgacgg agaagtttta gtagatacga cagatgtcga taactttttt
    22381 gacaatccaa gcgaagctcg tgcccaacaa ttcctcagca aaattatcaa ccacgaaagt
    22441 gacaaagtca aataaggagg cgcctatgaa aaaaaattct ttttatcagc attattgatt
    22501 agccttttcg gccttgctgc tgccaaacca gtccaggctg atactagtat cgcagacatt
    22561 caaaaaagag gcgaactggt tgtcggtgtc aaacaagacg ttcccaattt tggttacaaa
    22621 gatcccaaga ccggtactta ttctggtatc gaaaccgact tggccaagat ggtagctgat
    22681 gaactcaagg tcaagattcg ctatgtgccg gttacagcac aaacccgcgg cccccttcta
    22741 gacaatgaac aggtcgatat ggatatcgcg acctttacca tcacggacga acgcaaaaaa
    22801 ctctacaact ttaccagtcc ctactacaca gacgcttctg gatttttggt caataaatct
    22861 gccaaaatca aaaagattga ggacctaaac ggcaaaacca tcggagtcgc ccaaggttct
    22921 atcacccaac gcctgattac tgaactgggt aaaaagaaag gtctgaagtt taaattcgtc
    22981 gaacttggtt cctacccaga attgattact tccctgcacg ctcatcgtat cgataccttt
    23041 tccgttgacc gctctattct atctggctac actagtaaac ggacagcact actagatgat
    23101 agtttcaagc catctgacta cggtattgtt accaagaaat caaatacaga gctcaacgac
    23161 tatcttgata ccttggtcac taaatggagc aaggatggta gtttgcagaa actttatgac
    23221 cgttacaagc tcaaaccatc tagtcatacc gcagattaag gaggataccc tatgacagat
    23281 ttatcatctt ggacagccta ttttcaggat tttggacaat ttttcaatgg tttcctcttt
    23341 actcttgccc tagcgattgg atcctttatc ctcgccatgg tcttaggagt cttctttggt
    23401 gccatgtcaa ccagtaaacg tccaatttta cgcattttag ctcgcatctt tgtggaattt
    23461 taccaaaaca ctcccctctt ggtgcagttt gttattgttt tttatggcct acctcttatc
    23521 agtgaccata ctatcatgat tccgatttat tggacagctg ttctctgcgt gggactctat
    23581 cacggcgctt atatcgctga ggttattcgt tcagggattc agtctttaca tcctgattgc
    23641 cctcatctac ttcagcttta acctagcaat ttctaacctg tctcatatgc tagcaaaacg
    23701 ttggcaacaa gctgcagaat aacaaattag ctctctagtt cattggagag ttttttgatg
    23761 atagtagata tttatagacc tcaatttgac accatacatt ttctatgata aaatgtaaca
    23821 aattcattta caacaaatcg aaatctaaat gaaatggaat tttctatgaa atcagtcaaa
    23881 ggactactct ttatcatagc tagttttatc ttgactcttt tgacttggat gaacacttct
    23941 ccccaattca tgattccagg actagcttta acaagcctat ctctgacttt tatcctagcc
    24001 actcgtctcc cactactaga aagctggttt cacggtttgg agaaggtcta caccgtccac
    24061 aaattcacag cctttctctc catcatccta ctaatctttc ataactttag tatgggcggt
    24121 ttgtggggct ctcgcttagc tgctcagttt ggtaatcttg ccatctatat ctttgccagc
    24181 atcatccttg tcgcctattt aggcaaatac atccaatacg aagcttggcg atggattcac
    24241 cgcctggttt acctagccta tattttagga ctctttcaca tctacatgat aatgggcaat
    24301 cgtctcctta catttaatct tctaagtttt cttgttggta gctatgccct tttaggctta
    24361 ctagctggtt tttatatcat ttttctatat caaaagattt ccttccccta tctagggaaa
    24421 attacccatc tcaaacgctt aaatcacgat actagagaaa ttcaaatcca tcttagcaga
    24481 cctttcaact atcaatcagg acaatttgcc tttctaaaga ttttccaaga aggctttgaa
    24541 agtgctccac atcccttttc tatctcagga ggtcatggtc aaactcttta ctttactgtt
    24601 aaaaattcag gcgaccatac caagaatatc tatgataatc ttcaagccgg cagcaaagta
    24661 accctagaca gagcttacgg acacatgatc atagaagaag gacgagaaaa tcaggtttgg
    24721 attgctggag gtattgggat cacccccttc atctcttaca tccgtgaaca tcctatttta
    24781 gataaacggg ttcacttcta ctatagcttc cgtggagaag aaaatgcagt ctaccttgat
    24841 ttactccgtg actatgctca gaaaaatcct aattttgaac tccatctaat cgacagtaca
    24901 aaagacggct atcttaattt tgaacaaaaa gaagtgcccg aacatgcaac cgtctatatg
    24961 tgtggtccta tttctatgat gaaggcactt gccaaacaga ttaagaaaca aaatccaaaa
    25021 acggagctta tttacgaagg attcaagttc aaataagtaa tcatactctc ctggaatttc
    25081 ccaggagagt tttttatagc caaatgaaat aagaccggaa cgatggaatt ttggcattca
    25141 aatcaattga taagaatatt ttatagtgga gtgaaatagg atacgaacaa attgattagg
    25201 aaaatcaaat gaatttatag aaatctttta gcagttatgt tatcctattc tagtttcaaa
    25261 acgctataga agcagcattg tgctagtcta gattcagttt actatactaa aacgagtagc
    25321 ttgaaatcaa aaaacccacc ctcacaggca ggttttatct gtattattca gctagattat
    25381 gctttacctt ctgaaccgaa tacgtcgata cgttcttcaa ccgatgcttg gatagctttt
    25441 acaccgtcag ccaagaattt acgtgggtcg aagagttttt tcttgtcgta ttctgcttcg
    25501 tttgcttcgt agtcacgagc aaatttacga gttgcgttag cgaatgcgat ttggcattct
    25561 gtgttaacgt taactttggc aacaccaagt ttgatagctg cttggatttg ctcatcagga
    25621 atacctgatc caccgtgcaa tacgattggg aatcctggaa gagcttctgt caatttttgc
    25681 aagtggtcaa ggtcaagacc ttcccagttt actgggtaag gaccgtggat gttaccgata
    25741 ccagctgcca agaagtcgat accagtttca accattgctt tagcgtcttc gattggagcc
    25801 aattcacctt taccgatgat tccgtcttct tcaccaccga tagtaccaac ttcagcttct
    25861 actgagatac ctttagcgtg tgctttttca acaacttctt tagccaattt aagattttct
    25921 tcaactggaa ggtgtgaacc gtcaaacatg attgaagtat aaccaacttc gatacactca
    25981 agtgcatctt cgtagtgacc gtggtcaagg tggatagcta ctggtacagt gatacccatt
    26041 gattcaacaa ggttagcgat caagttgcga gcaactttgt aaccacccat gtatttagca
    26101 gcacccattg aagtttggat caaaactgga gcttttttag cttctgctgc gcgcaagata
    26161 gcttgagtcc actcaaggtt gtttgtgtta aatccaccaa ctgcataacc gttgtcacgg
    26221 gctgcttgga caaatttttc tgctgaaacg attgccattt tatcaggcct cctgtatatt
    26281 tttatgggtc atcccattta cattgttcat tttatcactt tttgccaaaa aaatctagtt
    26341 tttcccgcag tttcgattga ttttcttcta actccatcta tgtaaaccct ttctctccct
    26401 agtcttgggc gacttttgga aaatctataa agaaggttaa acgattctcc tccatctcga
    26461 aacgataagc taatttttca tgttctaata gactcttaac cacaaagagc cccataccag
    26521 accccttgac cttgcgacta gcattgtcag aaaaagactg ggctagtttt tcttgttcct
    26581 ctgagctaca gctattttcg ataaaaagtt ctccttctct ttctccaatt cgaactaagc
    26641 cacctggaac agagtgctta atggcattgc tgatgagatt agaaagaatc aacttcataa
    26701 ctgatgggtt tagataagcc tgctgatggg tcaaactatt gtctatctgg agctctcttt
    26761 ccttggctag caaggcataa tctttgacca gattttgcgt catctggagg aggtcaattg
    26821 tttccctatc atctcgcaat tcctgcacag aagagaggga aagtatctgc agaacatggt
    26881 gattgagttc atccacaatc cccaaggcaa ctcccagata ctggtctcta tccttataac
    26941 gaccgatatt ctctctcata ttttcgatta ggattttcaa actagccagc ggtgttttca
    27001 attcatgaga agctcctcgt aggaattcga ccttcatctt ctccagctgg agaatggctt
    27061 cattcttttc atgcaagtcc gcaataacag tcaagagatg ctggtagagg ctattgattt
    27121 gttccttgag attacctatc tcatccttag aatccacgcg caatcgcact tgggaatcca
    27181 ggtccatcat ccgacgggtc acccgcttga tttccaaaat cggtgcaaca atagtccgag
    27241 cgtagatgta ggccaccaag agggaaatca gaaaggaggc cagcaaggta tagggaagaa
    27301 actggagact gatttgctcc gcttcctttt gtaaatccat ggaagctaga aactggagaa
    27361 tcatagtacc accgtcttgc gttttcacct cgcgctcctc aataaagaga gaggttgtct
    27421 ggcggtctgt gtccagagga agactgtcct tgacttctaa cttgtcctcg gtcatctcac
    27481 ctttgacggt ccccttgata tcactagtct gggaatacaa atctaacact tgctcgatac
    27541 tctgcctatc tttcccttct agggactggg caatggctgt tgccttttga ccaatggttt
    27601 cctgacgatg actcagataa gtcgaaggaa aaagaaaata aatagctaaa tgaaggcaga
    27661 taaccagaac actaaatatc gagaaggtat agataaatat ctttgcaaat aaacctgttc
    27721 gtttcatttt cgctccaatt tataaccaac attgcgcaca gtgaggatac aatccaagtc
    27781 tagctttttc cgcaattcct tgatataaac atcaataaca cggtcaaagg gaacctcatc
    27841 tgtcgctttc cagacggcat cgataatctg agaccgagtc aaggcccggc cttcattttt
    27901 cactagatag tccagaattt ccaactcttt ggcattgata ggcacttctt gacctgcgag
    27961 gcttgcactg tagctttcaa agtccacctt ggtatccttg taagaaaaga ttcgtcctgt
    28021 atcgtagtag cgcttgaaaa tcgcgtccac cctcactttt aagagggaga gggagaaagg
    28081 tttttccaga tagccatctg ccaaagaggc aaaggcactc atcttgtatt cctcatcctg
    28141 aaaagctgtc aacatcaaga caggaacctg actggtttta cgaatctcag ctagaacttc
    28201 taagccgtta agcttgggca tctggatatc cagtaaaacc agggccacct catagctaga
    28261 aaattgctcc agagcttcct gaccgtccgc tgcctcaata gtttcatagc cacaatccgt
    28321 caaataatca ctgaccccct cacggatcat ctcttcatct tctacaatta aaattttcat
    28381 actttaactg ctctctattt tttatttttc ttagaataaa tacctactct attttctatt
    28441 atagtctctt gctggccttt tgtctgtaag taactgatca ctagataaaa cgttgtgaaa
    28501 ttcctttctc ataaattcca tagctttagt atattatatt taagcaataa agtacaaaga
    28561 aaacaactga aagcaatgat tttcaccact gctttcggat ttattttgaa ttgttaaata
    28621 gccattccta tccactattc ttgaatagaa acacaagatg caatctttat tccagactca
    28681 ttttttcaaa tttattcacc atccagcaag agctcttttg gttgttttct aaggagattg
    28741 cttgaagcaa gcgccataac gagaaccact agaaccaagg caaggacaaa aatgatgata
    28801 aagtctgatg tctgaataga aatgtctagg ctcgacaagg tcttgctaaa gccatctact
    28861 tctgcaccac caccaaggtt agaggcttga gccgccttac tagcctgttt ggcaacacct
    28921 gaagtcacat tggcaaggac agtgtttcca attgcacggg cagtgtaatt agctaggaag
    28981 taagcagaaa ctagagcagg gatagcaatc aagatagatt cggtgatgaa ttgacccaag
    29041 atacttgcct gcttgaggcc gatagagagg agaattccca cttccttgcg acgggcgttg
    29101 atccaaaggc tgagcaagag ggcaaggagg agaactgaga agctcaagct accccagaag
    29161 aggaggttgg ccatcttgta cataccagat atagattgct caagagctgg gtagttagag
    29221 gagctcttga cgagtgtgta gctcttccag ttgataccac tgatgccatt caactctttc
    29281 ataacatcat ccaagttctt gtctgctgtt acaaagaagg ttgcgtcccc ataaatggct
    29341 gtgtcttctg tgtatccata aagttttgca gcagtgtgaa tgtctgtaat agctgtgttt
    29401 tcgtaaagtt cttgtgagta ggttactgct gacttattat gaccatcaaa gagtcccttg
    29461 attgtcactt caactgtttc cttggctcct ttttcattat ctgcatcgta gatattagag
    29521 tccagtttaa ccttgtcccc tactttccag ccgtgtttgg ctgccaagtc cttgtgcaag
    29581 aggattttat ccttgtcgtc gttggttaag tgctctcctt cgactagttt ataagaacca
    29641 gagacaaact tgtcttcttt agaggagtca ttgacacctg taatcatcaa gctacttcca
    29701 aaacgtttgg cacgatcagc agtgagattc ttcttggttt ctggcgtttc aatcaggtca
    29761 tatccagtca aatctccgat agcgttgata cgtttgacat aagactcaat ggccttgttt
    29821 tcggtgattt ttttgatgtc ttcacccttg atattcccag caccgcgagg cgttccttgg
    29881 ttgacgcgac gattgatttg catggagaag ctattggtga tatttttaaa ggtctcctga
    29941 gaagccttgg cagtagctcc cttgattgac aagccgacca aactcaagct cgccatgagg
    30001 agaataatca ggaagatgac aatcgatttg aaaaacttcc ttgtaacata ggcaaatgcg
    30061 ttgtgtaaca tagattccct ttctagattt tgttttaatc attctatcaa aataagctca
    30121 aattatttac tagtattgcg cgtttcagtc agtttcttat cctttaattc aagtgtaata
    30181 tctgacgctt gtgccacttc tttactgtga gttacgacaa tcacacattt acctgttttc
    30241 tgggcaagtg atttgagtag ttcgacaata tctccagcag ttttaggatc cagatttcct
    30301 gttggctcat cagctagaat aactggagct tctgagacca aactgcgagc aatggcaaca
    30361 cgttgctgtt gaccacctga taactggaga acattccgct tgatctggct ttcatccaaa
    30421 ccaagctcaa gaagtgtatt cttgcttgcc tttttgttga ccaatcggat attttccagc
    30481 ggagaaagat aatctatcaa gttataattt tgaaagacca gggaaatatg gtgcatgcga
    30541 tggtaagaat agcccttctt acgaatatcc tctccttgaa aaaggataga accttcaaca
    30601 ggactatcta gaccagcaag tagggacaag agtgtggatt ttcctgctcc tgactcccca
    30661 ataatactgt aaaattttcc gggttcaaaa ttataattga tctgatatag gactgcttca
    30721 gcagtattct tataacggta ggtaacatct tgtaattgta ataaagtcat gatttctcct
    30781 tcttaactaa tagatgataa aatttctttc ggtgattttc taaataagaa taggaaacaa
    30841 agggctacag ataagcaact aagcagaact agaaaaacat aggattctgc aaaagataag
    30901 atactagttg ataaactgct tgctttggct agtgtatctt gtaagcttgc ctgatctcca
    30961 cttgctagta gagtttggag taggtaagtt gtgattccgt ttcctgcaac aaatgctgga
    31021 agcaaagctc caagagatac caaaactacc tctaaacaga attgtaggaa gatcgagctc
    31081 ttgccttttc caagtgcaag taaaatcccc acttcataga cccgttctct caaccagaga
    31141 gacaaaacca gaattaaggc tccagctcct gctatcaaca tcccataaag gaagatggtc
    31201 aggaaggttt ggaaagttgc aactgagtct ttgatttgtt caaaagcctt gttttccttt
    31261 tcgacttggt agccttgatt ttccaaggcc aagttttcta cctgcttcat gagtccgtcc
    31321 atttccttag gattttctac atagaagcgt gctgcactga cttgagcttc actattgccc
    31381 aaaagggttt ggctactttc atagtctgta aagacttgat tttcactgaa gtcagaagac
    31441 aagcctgtga atttctcttg ttttttacca gaaaagatgc caataatctc aaactctact
    31501 gtttgtcctt ttccagattc agactgacca gcatccaagc caatcttgtc atgaagtgaa
    31561 agaccgttct tcttagccaa ttcttcgtgg ataaggattt tcttggaatc ccctttttga
    31621 aggtgtcgcc cttcttttag attgaaagcc gaactggtaa aggttacatc cttggatgaa
    31681 tcctcaagag ccgttaagct aaccaagtta ttgtctgcag ctgataaatc atcacgctcc
    31741 acgctctgct cgccagtcac tgcttccttg tcttttagtt ttgcgaccgt ctcaagttca
    31801 ggagagacat tttccagccc cttaatcttg cttacagatg ctaggtctga caacttgaat
    31861 gtctgaccat tctctatctt cttaatagaa aaagatgtat tgagtgattt ataaagattg
    31921 ctttctactg ttttgttgga cttcatcaga gtcaaacagg ctgaaattcc ggccaataag
    31981 accaataaaa tcagaaataa aataaaactt ctcagtcgct ttctgctgac ataagcccaa
    32041 gatctttgga ttggattcat ttgtcacctc catatttgta agactattat aaaacccaaa
    32101 tatgaaatgt ttatgaaata cgaaaaaaaa tatcgagtag gggataatct ctcgcccctc
    32161 tcacaccacc gtacgtgccg ttcggcatac ggcggttcaa ctaactttta acgcatgtcg
    32221 ttcaaggtaa taatccaaac acgaaacctg ttcacgtttt tcaaggactg gttttgatat
    32281 agcacgttta agtaccgact tctgagctac tatagtagat tgaaactaga atagtacatc
    32341 tcttcttcta aaacattgtt agaaatcgat ttgacttccc tgatcgattc gtcctattct
    32401 tatttcattt taatataatt gatagtggtc gccccagcca gataccttat ctgctatcca
    32461 tttaggaacc cctaacttaa gcaatcccca taatcgtctc gatttcttct tccattgctt
    32521 ccagataatc actcgtaggc gagtacgcaa gcgctcatct atgctagtga ctatactttt
    32581 catatttata attcattcct ttcgtttcac tcaaggcaca acacagaatg aaaaagtgtt
    32641 gtgatcttta ttttgtttta taataatagt gagaaagcct atcactacta caaatcacga
    32701 ggaggtgaat aagtgagtgg tacagccact acctcgcata ttttgtcaca tcatttaacg
    32761 gtacataata agttgtacca tctgaataag ttgctacaat atcatttgca tgctctcctt
    32821 cacctttagc aaaggttgga gctcctgctg gatgattttt atttgcctct ttcaattttt
    32881 caataatggc atttttttct gtatctttta tattatcagg atttttcact aagattttgt
    32941 ctggatatgt cggtttagca gaaacaattt ttactgttat ttctttttta ttcgaagcac
    33001 ttgtccagtt tccagcatta tctttagtat ttaattttac agtaattcct gaactaggaa
    33061 cttcagtagc aggttgatta tcaacattat tcaactttaa tttcaaaaga gctgttgcat
    33121 cagacgtttt atcaatcgtt atatataatg ataaattgtt attataacca gtttcttcat
    33181 atttagctgt ttgtgagcta cttgaaacag aactgaaatt atgcccacta cctccctgat
    33241 tatcttcaat gcttacgtct aaatgaactt ccccactatt atttggctta gcaacaactg
    33301 ttatagtaaa ataacataaa atttgcataa atagattagg gaaatcaaag caacttctag
    33361 gaatgtttta gcagtcacag tgtactttcc cagcatcaat ccactataac tctgcacata
    33421 aaaatggaga agatggccat cctcttctcc aaatattaac ttctttacaa accaactata
    33481 gttgacaaag aacctaaaat caattgataa cacaaggtca ggtcggtcaa ctctttcaac
    33541 tgaagccctg tcaactcttc ccatttatca atcttgtatt ggagagaatt gcggtgcaga
    33601 tagagttgct gggctgtttt agtgagaaca gcactatttt cccaaagaga gagaatgatt
    33661 tcctgaatct gatcttgatc caaaatcatc tggtgtagac attctttaat tggcttcaag
    33721 tccacgagtc tttctcccat actccaaaga tagagctgag aaaaagtatg aacaccttgg
    33781 tgaccctgac gccaccatgt cttgaacaaa tcccgctcag ctttgattaa gtctgatagg
    33841 gcttgatgtc ctgtctgaga ccaaacctga cccaacatga tagaaagacg aagtccaaag
    33901 tcatactcaa ccgcttcaat cgtatcactt aaaatatctc ttacagaagt gtatttgtct
    33961 tgttgaagca cgaaaacata atcctgagat ccgacctgta gcactgtctg acaattcgga
    34021 aaaagagtcc gcatcatatc tagccaagaa gccagatttt cctgctgaaa ataagaaaga
    34081 tggcaataaa ccaactgaat ctttttaaaa acttgcggtg cctgtccctt gccttcaacc
    34141 agataggaat accaagggtt tagcgaacga gcctgctcct gctgggtcaa aagggcaacc
    34201 aactgctttt cacgctcgct gagcccagct tcctccagca aaatccactg ctgagaagct
    34261 aaaggaagcg tgagatagcc ctctttctct actggttggt ctgaaatccg agcctcagga
    34321 aaccagtctt gtagttcttt tgccctcatg ttctagccct ccactttttg gatgcaccat
    34381 gaaaccaaac tctcaagacg ttccagattc tcagtcatat ggagatagcc cataactgct
    34441 tcaaatcccg tggacatacg ataagtcacg acatctgcat ttttagcctt tgtgtgacta
    34501 ttggtattgc ggccacgttt gtagatttct tcttcttttt ccgttaggat ctgctcctcc
    34561 aacatgagag caatcagacg agcctgagcc ttggctgaca cgtacttggt cgcctcttgg
    34621 tggagtttat tgggcttggt catacctttg aggatgaggt ggcggcgaat atacatagaa
    34681 tacaccgcat ctccctcaaa ggctagcgca atcccgttaa tgagattgac atcaatcacg
    34741 tgtccacctc actccatcct tggtatcaag gagcttaatt ccttgagtaa ccaattggtc
    34801 acggatttgg tctgctgtct caaagtcacg attggcacgc gcctcttggc gtttttgaat
    34861 caagtcttca atctctgcat ccaaaacttc ctcaacaaag acaattccaa aaatttctaa
    34921 catatctgca agagcttgct tgacacttgc atcatagttc cctgagttga tccatttggc
    34981 catttcaaag acaactgtga taccgttggc agcattaaaa tcttcatcca tagctgctac
    35041 aaacttatct ttaaagtttt gtaactcttg ggcatccacg tttcctgtaa atggttgttc
    35101 gtaagtattc ttcagatact tgagattggt ctcggcatcg cgaactgcct tttccgtgaa
    35161 gttgataggc ttacggtagt gctgggtcgc aaagaagaaa cgaagtactt gcccatcaag
    35221 agttttaagg gcatcgtgta ccgtaatgaa gttacccaag gacttagaca ttttgacatt
    35281 gtcgatattg acaaagccat tgtgcatcca gtagttagca aaagccttgc ctgttttagc
    35341 ttcagattgg gcaatttcat tggtgtggtg tggaaactct aggtcagctc caccaccgtg
    35401 gatatcaatg gtatcaccta aaatctctgt cgacatgact gaacactcaa tatgccaacc
    35461 cggacgtcca ggtccccaag gactatccca agaaatctca cctggtttgg aagatttcca
    35521 tagagcaaag tctacaggat tttccttacg agccgtttct tcatcggtac gacctgaagc
    35581 acctagctcc aaatcttcca aggttttatt agccaattta gcatagttgt gggatttttc
    35641 tacacggaaa tagacatccc cttgactctc ataggcaaag cctttctcga tcaagtcttc
    35701 cacaaaacgg atgatgtctg ccataaactc cactacacgc ggatggcgag tcgcaggttt
    35761 cacgcctaag gccgtcacat cctcacgaaa ggcagcgatg tacttatccg caacctcctg
    35821 aggtgtgatg ccttcttccc tggcacggtt gataatctta tcatccacat ctgtaaaatt
    35881 ggaaatatag gcaaccttat acccacggta ctcaaaatag cgacgaatcg tatcaaaagc
    35941 taccgtcgaa cgggcgtttc ccacgtgaat atagttgtac acggttggcc cacaaacata
    36001 catcttgatc ttgccgtcct caatcgggac aaattctcgc aaatcacgag acatggtgtc
    36061 atagatttta atcataaatc ataatcagga aagctaaaat ccaagaactg ttagtttcat
    36121 cactaaacta agagctcaag taaatttcag tccgaatgtc tctacacttc ggaatccctt
    36181 gctcctttct cattcagata aaccacctgt gtctgtttga caaagccaat tttttcatac
    36241 aaacgtttgg cacctacatt gctatcttcc actgcaatct gaaattcctt gtcattttgc
    36301 tcaattagtt ggttgacgag ggattttgct aagtagcttc catagccttt cccacgttca
    36361 ggttccgata ttgctaaacc gtagaagtaa ttcgtattag tcgataaatc taccgtgcaa
    36421 gtcccaataa cctgaccgtc ttttaacaaa atatataagc gactttctgg atccttcaga
    36481 gcttcagcga catatctatc cacaacttct ctcgattcat gttcctctga aaatgcctga
    36541 aattttaatt gactaatttg atcctgatac gaactatctg ctaacaaaac ttcaagatgg
    36601 gaaacatttg ctaacggata aggtcttcta tccttaccta accaagtttc tgtctcttca
    36661 tcctcgatta gtccccagtt actggcaaag tcaggatgat tctctaaaaa aatacgttct
    36721 gtctgaaaag tgactgaccg aatggggaaa gaagctgttt ctctctcaaa actagtaaac
    36781 aatgcacgcg caatcccctg acggcgatga cctggatgaa ccaatatcgt cacttctaca
    36841 tcttggtcat ctgcatagac agttaataaa ccaacaagtt tgcctttttc ataataaagg
    36901 aaaaaggcgg gcatgtttgg gtcaaaatta agcatgttag agagataggg atcgcgatag
    36961 gtaccgtcat agttttggca acagttaatt acttttttcg cctcagatag ctcctcttgg
    37021 cttaacttgt ttcttgcttg aatcatatag gtatcctcta caaaccagac gatctgtgac
    37081 tggcatcttt agcctgctcg agtttattga cataatactc ccgtttttct tcgacttcgt
    37141 gaataacagg ctcatctttc ttaccatgaa gacggacaat cttggccgga ataccgacaa
    37201 ccgtcacatc actaggtaca tctgctacga caactgctgc agcaccgacc ttggcatttt
    37261 caccaatttc cacaggcccg ataacttggg catgggctga tatgagggct ccctttcgta
    37321 cagtcggatg gcgtttgcca cagtctttcc ctgttccccc gagagtcact ccgtgataga
    37381 gaagaacgcc tttttcaaca atcgctgtct ctccaatcac cagaccagaa ccatggtcaa
    37441 taaagacacc tgaatcaatc tgggctcctg gatgaatctc aatctgagtc caaaagcgcc
    37501 aaaactgact gtgcatacga gctaagagtt tgaagtcgta cttccagaga aaatgcgaga
    37561 gacggtgggc cgccaaggcc ttgacacctg gataagtcag caaaacctcc aaagtggtgc
    37621 gggccgctgg atcattttct tttacgatat caatggtttc gtgccaccac cccatacatt
    37681 tctccttttc ttactctgaa tcttttggtg tttctgtaaa ttctttctta ggtttgtgat
    37741 ccttgtgatg acgtgggcgg tgagggcgct cagacttttc acctttttca tcatgctcag
    37801 gttttggcgg acgaggtaga agagccttca tagaggcatc gatacggcct ttttcatcaa
    37861 tcttgataac cttaacatca acttcatccc cgatttctac caaatcctct acacgattgg
    37921 tacgagtcca agccatctca gagatatgaa caagggcatc tgtcttatca aagaggttaa
    37981 caaaggcacc aaatttctcg atacgaacga ctttagcacg gtaaacttca tccactttgg
    38041 cttcacgaac caaaccagca ataatttctt tggcacggtt aatagcatct tggtcactag
    38101 agtagataga cacatttcct tcttcgtcta tatcaatctt aacacctgtt tcagcgataa
    38161 tcttgtcgat ggtttctcca cccttaccga tgacaatctt aatcttgtcc acatcaatct
    38221 tgatcgtatc aattttcgga gcagttggag ccaattctgg acgaacttct ggaatggttg
    38281 cttcaatgac atcaaggatt tcaaaacgcg ctttcttggc ttgagcaaga gcctccgtca
    38341 agatttctgc agtaatccct tgaatcttga tatccatttg aagggctgta atcccatcac
    38401 gagtacctgc aaccttgaag tccatatctc caaagtgatc ttccaaacct tggatatctg
    38461 tcaatactgt gtagttattt ccatctgaga taagtcccat agcaatacca gctactggcg
    38521 ccttgattgg cacaccacca gtcataaggg caagagttcc cgcacagata gaagcttgag
    38581 atgaagaacc gtttgattcc aaaacttctg ctactagacg gatagcgtat gggaattctt
    38641 ccaagcttgg caagacttga gcaagagcac gctcaccaag ggcaccgtga ccgatttcac
    38701 gacgacctgg cgcaccgtaa cgacctgttt cccctacaga atattgaggg aagttatagt
    38761 ggtgcataaa gcgtttcttg tactctggat ccaaaccatc aatgatttga gtttctccca
    38821 tcggagccaa ggtcaagact gaaagagctt gagtttgccc acgagtaaag agacctgaac
    38881 catgtacacg aggaaggaag tcaacaaccg catccaaagg acggatttca tcgaccttac
    38941 gaccatcagg acgcaccttg tcttctgtaa ttaaacgtcg cacttctgcg tgttccattt
    39001 gttccaagat ttcagccaca tcacgcataa tacggtcaaa ttcttcgtgg ttcgcatatt
    39061 tttcttcgta aacggcagtc acttggtctt tcactgcttg agttgcagct tcacgggcca
    39121 atttctcttc tacttgaact gccttttgga ggtcactgtt gtaggctgca atgatttcag
    39181 cttgcaattc agcatccacg tgaagcaatt ccacttctgc tttttcttta ccgacagcag
    39241 caacgatttc ttcttggaag gcaatcaatt ctttgacagc ttcgtgccct ttaagaagcg
    39301 cttccaacat gatttcttct gacaattctt tggcaccaga ctctaccatg ttgatagcgt
    39361 gcttggttcc agctactgtc aattcaagaa gagattgctc tgcttgttct tgacttgggt
    39421 tgatgatgat ttggccatct acatatccca cttgtacccc agcaattggt ccgtcaaatg
    39481 gaatatctga aatagacagt gccaaagatg aaccaaacat agcagccatt ggtgcagatg
    39541 cattttcatc ataagaaagc actgtattga tgacttggac ttcattacgg aaaccttccg
    39601 caaacatagg acgaatcgga cggtcaatca aacgcgctgt caaggtcgca tctgttgaag
    39661 gacgtccttc acgtttcata aagccaccag gaaacttccc agccgcatac attttttctt
    39721 cgtagttgac ttggagtggg aagaaatccc cagttgccat tttcttagac ataacggcag
    39781 cagtcaagac agttgactca ccgtaacgta cgacaacaga gccatttgct tgcttagcaa
    39841 cctgaccagt ttctacaatt aactcacgac ccgcaaaagt cgtttgaaac acttgttttg
    39901 ccattttaat cccctttgga ttgatgaaat tatacgcctt gcctacaaag atcaagatac
    39961 caaggacgtc aaaagcaaag taaaaatagg aaactgacga agtcttcgat gaagacaaga
    40021 cagtttatct tttttacaca gcttttcggc cgtgttcaat tacacaagat attttggacg
    40081 gttcggcttg ccgaacattt ctgtagaaaa ataggaaggt gacgtcgcac tcgacgagtg
    40141 ctaggaagct tatctttttt cctaagaaat gagaccaaaa ttcaagtcat caagatacca
    40201 agccgtcaag caactcaaag gaaaatagga aatcgaacga cggagcgact gctcctaggg
    40261 agatttatct ttttccacag agttgtaggc aagttcagtt ttcaagatac atcattagaa
    40321 aggtttaata ctaaagtatc taaagctttc acgctaatcg ctatcgggcg attagctaaa
    40381 tgctttacta actctctcgt caaataacat cgatttgact cactcgtgtc gttaaatctt
    40441 acagtttaaa tgcattgtat tatttaatac cttcatcttt gtatcaagta cgtacagaat
    40501 ttattttatc atatttttct taaaaagtga ggtctttacc attaaaaagg aaccattccc
    40561 ctcacctgag aagaatggtt tgcttttatt atcctagaga ctggtgatta aacaaggcat
    40621 gggttgcttg atggatgtat tttgctgtat cagcattatt catcgtatag agatgcacac
    40681 cggcaacatc ctgagttacc aagtccacga tttggtccac tgcataggca agtcctgctg
    40741 ctctgagcga ctcagggtca tgctcatact tgtctaagat ggctttaaat ttgcgtggaa
    40801 gatggatatt ctcacaagtc ttcaagagtc ggagagcctg atttcgattc agaattggca
    40861 taattcctgc atgaatggga acatcaatcc cagccaaaat acacttgtcc tgaaaatcat
    40921 agaagcgctc attatcaaag aagagctgag ttacgaggct cgaacagcct gcatccactt
    40981 tcttcttaag attttgaata tctgaaatct gatttggcga atctggatgc ccttctggat
    41041 agcaagctcc aataatatca aagtgagggg cttgttcctt gataaactca atcaagtcgg
    41101 ttgcatagcg gaaatccttt tgtggttcta cgtctggaat aatatcccca cgaagagcca
    41161 agattttctg caccccaact ttgtccaagt cagcaatagt ttcagcaacc ttgtccttag
    41221 ttagataaat agctggcaag tgggcaatgg tcggaatcgc caagtcattt tggataaagt
    41281 cagccaaacg aaccgtcgtt tccttgatat taaatttatt attgctggca gttacactga
    41341 taaaatgggg agccaactcc tgcatatcct gcaaggctga aataatgtta ccattaccca
    41401 cggctgggtt tggagggaac acttcaaatg agagtgacgg tgtttggcgt gacatatgta
    41461 ataacctttt ctagttgatt tctttttgaa caaccactgt atggagagaa atccaatctt
    41521 acaatttctc acgcgcagct ttagctgctt caacaaggcg gatcaagctt tcttttgttt
    41581 ctgggatacc acgtgttttc aaaccacagt cagggttgat ccaaactttc ttgcttggca
    41641 ctttagcaag gatggcttcg attgtgttgt cgatttcgcc ttcatttggt acacgaggtg
    41701 agtggatatc gtaaacccca ggtcccactt ctgtttggaa gtttttcgct ttgagttcgt
    41761 ccaagatttc aaggtttgaa cggctagctt caaaggaaat aacgtctgca tccatgttat
    41821 cgatagctgg gatgatatct gtaaattctg agtaacacat gtgagtgtgg atttgtgtgt
    41881 ctggcgctac tgttgagtgt accaagcgga aggcaggaat agcccagtca aggtagtctt
    41941 cgtaccagtc gctacggcgg agtggcaatt tttcacgaag agcagcctcg tcgatttgga
    42001 tgattttcac accagcagct tcaaggtcaa gtacttcatc cttgatagca agggcgattt
    42061 gaagagttga atccttgata gagatgtctt cacgtgggaa tgaccagtta aggatggtaa
    42121 caggtccagt caacatacct ttaacaggtt tgtttgtacg actttgtgca tagctagacc
    42181 atttaacagt gatagagtta agacgagtga catcacccca gatgattggt ggttttaccc
    42241 cacgcatacc gtatgattgt acccatccat ttttagagaa gaggtatcct gacaagtttt
    42301 gaccgaagta ctcaaccatg tcattacgct caaattcacc gtgaacaagg acatcaaagt
    42361 caatatcttc ttgccacttg atccattcgt caatcgtttc agcaaggaaa gcatcgtact
    42421 ctttttgaga caattcacct ttacggtaag ccaaacgttt ggcacgaact tcttttgttt
    42481 gagggaatga accaatcgtt gttgttggaa gagctggaag tttgaaagct tcttcttgga
    42541 tagcttcacg ttctgcaaag gctggcaaac gagtgtagtc tgcgtctgtc aagccagcga
    42601 tacgcgcacg aagttcagca ttttcaccaa cacgctcagt cgcaaagagt tctttgttgg
    42661 ctgcaagagc ttctgaacct tgaccattgc ggatagcatc caagtcacgg atttcatcca
    42721 atttttcaac tgcaaaggca aagtggttca agagtgctgg ttcaaattct tcattagcag
    42781 ttgtaaatgg cacatgaaga agtgagcaag agcttgtcaa aacgatgttt tcagctggga
    42841 tttgctcaag aacagccaag ctcttttcgt agttgttgcg ccagatgttt ttaccattga
    42901 caatacctac atagagagtc ttgtcagctg ggaagccacc tttaacgagt tcaagagttt
    42961 tcttaccttc aacaaagtca agaccgatag catctactgg caagtttaca aggtcagcgt
    43021 atacgtcacg aacatcaccg aaataagttt gaagcaagac ttcaagacct tttttgtcag
    43081 ccaagagttt gttgtaaagg ttcaagaaga gagctttttc ttcagctgtc aagtctttta
    43141 caagagccgc ttcatccaat tggatgcgag tcgcaccaag ttcagccaat ttagcaaaaa
    43201 cttcttggta agcaaccact aagctatcta cgaagtcgtc tgctttcacg ccttcttcaa
    43261 agtctgacaa ttgaaggaaa gtgaatggac ctacaagaac aggacgagtg ttcaatccaa
    43321 gttcttttgc ttcttggaac tcatcgaaaa tcttgtgacc agccaatttt acttgagtgt
    43381 ctttttcaaa tttaggaacg atgtagtggt agttagtgtt gaaccatttc ttcattggaa
    43441 gggcgcgaac gtcccctttt tctccctggt aaccacgtcc caaagcgaag tagcgctcaa
    43501 ggtcagacaa gtccaagttt tgaacggatg caggcaccac gttgaaaagg aaagccgcat
    43561 ctaggaagtt atcatagtga gaaaagtcat ttgatggaat ttcagtgatg cctttttctt
    43621 tgacaatgtt ccagtgttta gcacgcaagt cttttgctgc tgctaaaagt tcttcttctg
    43681 agatttcttt tctaaagtat ttttcagttg taaattttaa ttcacggaat tcgcccaaac
    43741 gagggaaacc gatgattgta gttgacatga tgtgtcctcc aaaatttgtt gttgaaacta
    43801 tcttaacaga aaagaaagcg tctgtataat tgtaaaaaat tagggtttga tatagtttga
    43861 aactatatat ctgtttcgga caaaagaaaa agacttgaag caaacgtctc aaatcctttg
    43921 taattcttac tttacagcta tattccaatt agaatactaa aacatgttat tagtaattct
    43981 tataagtgac tatgacctgt tattagaaaa gactataact gattctagtc aacttttccc
    44041 ctgttcaagt ggaacgactg ctagtgtctt tcctagactg gttagaactt ttaagaccgt
    44101 atccaactga agactgctct ctcctgtctc catcctagct atgacaggct ggcttattcc
    44161 actgacttct tccagctttt tctgactgat tccttgttca tacctagcct caatcaactc
    44221 gctcatgata gccactcgca tatcactttc aaggatttcc tccttgctaa agagctcaga
    44281 tggacatcct tccaattact cccaatagca ctattcttca tcacttaacc ctcttttttt
    44341 tacgtctatg tatttttaaa aaaatgagcg aattatgatt cgatagattg accagcgggt
    44401 ttaaagttgg tgctagccta tttcttaagc gcttttcctt ttctaggata aagcagatcc
    44461 tgcttgctta accccaattt tccacgatga atccaatagt aaatggttga aattcccacg
    44521 ttaacccctt tagccatcac catcatttca ggcgaaaatt tttggttatg atagtggaga
    44581 atcttttcct ttagtttctt agtcaagctt gatttcttga ccgagtgctt gcgattattt
    44641 tcataagact gttgagcgta gtcggcagaa taaatctctt tgaagcgccc ttttccaaga
    44701 cattgtcgga ctgtcccata cttgatttca gtatggatag tttgaggagc ttttccaagt
    44761 agagaggcaa tttctctatt tgattttcct tcttttttcc atcgttcgat taagcgacgg
    44821 ctatcgattg tcaaatgttt gccttttgta gtataattgt cttgcatttc tgtgcctttt
    44881 aatcatttca atcttaaatt ggactttttt tacttgggtt gtacttaatc tatgaggaag
    44941 acaagaaaaa gaatatcaat caagtaaagt cacaaagtca cattagctcc gagcaaccat
    45001 tgcaaattga ggtactcaca caatgattaa aacatttctc tctgcccttt cggtcattct
    45061 cttttctatc cctattataa cttattcttt tttcccatct tctaatctta acatttggct
    45121 atctacccaa cctatcttgg cacagattta tgccttcccc ttagctactg caactatggc
    45181 tgctatttta agtttcgtat ttttttccct atctttttac aagaaaaata aacaaatacg
    45241 gttttactct ggcattttgc tcttactatc gctcatatta ctattattcg gaacagataa
    45301 aaccctttct tctgcatcaa ataagactaa aaccttaaaa ttagtaactt ggaacgtcgc
    45361 taatcaaata gaagcacaac atattgagcg aatttttagc cattttgacg ccgatatggc
    45421 tatattccct gaactagcta ccaatatcag aggtgagcaa gaaaaccaga gaatcaaact
    45481 attgtttcat caagttggac tttctatggc caactatgat attttcactt ctccacctac
    45541 caatagtgga atagctcctg tgactgtgat tgtcaagaaa agttatggtt tctatacaga
    45601 agctaaaact tttcatacaa cacggttcgg gacaattgta ttacattcga gaaaacaaaa
    45661 tataccagat atcattgcct tgcatactgc tcctcctctg ccaggtttaa tggaaatctg
    45721 gaagcaagac ttaaacatca ttcataatca attggcttca aaatatccaa aggctattat
    45781 tgcaggtgat tttaatgcaa ctatgcgtca tggagcactt gcaaaaataa gctctcatag
    45841 ggacgcatta aatgtactgc caccttttga aagaggaact tggaatagcc aaagtccaaa
    45901 actttttaat gcaacaatag atcatatttt attgcctaaa aaccactact atgttaaaga
    45961 tttagacatt gtaagttttc aaaactctaa tcatagatgt atttttacag aaatcacatt
    46021 ttaattattt tatataaaat cacccctcta gtgttcataa actagagggg gaatttgtat
    46081 catactatcg tttaacgcac ttctgcattg actttttctt cgagcgatgc ttggattttt
    46141 tccatatagc gtgcgacttc ttcgtccgtt aagctatctt ctggattttg gaaggtcaag
    46201 ctataagcca ttgacttcat accaagtccc aatttctcac ctgagaagac gtcaaagagt
    46261 ttgatatctg tcaaacgttt cacgccggca gcttggatag catctacaac ttcttgatga
    46321 gtcacttctg ccttgaggag aagggcaacg tcacggctga ctgccgggaa tttggtgatt
    46381 tctacaaatg gagtcgctgg ctgaagcgca gcttcgatag ctgaaaggtt aagctcagcc
    46441 acatacgttt ctggaatatc gtaagccttg gcagtgactg gatgcacttg gccaaggaaa
    46501 ccaagaactt ggtcaccgaa tgaaatcacg gctgtacgac ctggatgaag gctagcgatt
    46561 tcagatgttg ctgtataggt tacttggagt cccaaacgag taaatagggc ttcaaggatt
    46621 cccttagcat agaagaaatc aactggaact gctgctgttt ggaaatcttt ttcagcaacc
    46681 aagcctgtca aggcaaaggc aaaactgttg atttcatttg gaagttcttc ttttggatta
    46741 cctgtttgtt caaagacttt tccaatctcg taaagggcca agtttttatt cttatgagcc
    46801 acgttgtagg caacggtatc aaggatacct gaaatcatat tttgacggag gactgaacga
    46861 tccacagtca ttggccacat gagttccgta aggttacttg gttgagccgt aaactcaact
    46921 gctttttcag gagttgttag agtataggtg atgatttctg tcaaacctgc tccttcagca
    46981 atagtacgaa cttgacggcg gagtttttgt gtggctgtca attcacctgc tgtaccatcg
    47041 tcttttggta gactagttgg caagcggtca taaccataga tacgagcaat ttcttcaaag
    47101 aggtcagctt cgattgtgat atcccaacga cgacgtggga ctctgactgt aaagctgtct
    47161 gcatttccag aaagaccaaa gccaagacga cggaagacgt cttcgacatc agcataagac
    47221 agctcagttc cgaggacacg gttaacatca gcaagagttg aagaaacttc tacatctgaa
    47281 gtatcaagct cacccgctga aacgataccc ttacgcaccg tcgcacctgc aagttccgca
    47341 atcaggctag ctgccgcatc aagggcttca ttaactgttg ccacattaat tcctttttca
    47401 aagcgagaag atgactcaga acgaaggttc aggcgaccac ttgtcttacg gatagatttg
    47461 ccattgaaaa cagcagcttc aaggacaaca tgactagatt tttcagagat ttctgttgct
    47521 tgaccaccca tgacacctgc aagggctact ggcttgtctg caacagtgat gactaggtca
    47581 ttcacgtcca agtcacgttc ttcaccgtcc aaggtcacca atttttcacc agcacgcgct
    47641 tcacgcacac ggatgtcagt cccttcaaat gtgtccaagt caaaagcatg cataggttga
    47701 ccaaagtaga gcaggatgta gtttgtcacg tctacaacgt tattgatggg acggatgcct
    47761 tcgttcatga gaaggttttg caaccattgt ggacttggtg cgatagtcac attgtccaag
    47821 atacgagctg catagtaagg cgccttgtct gtctcaatgc ccacagaaag ggcatctgtc
    47881 gcagcttcat ttgtttctgt caaagtaaat tctttaaagt tgactgcctt gtcatatatg
    47941 gctgccactt cgtgagccac tccacgcata gaaagggcat ctgcacggtt tggtgtgata
    48001 gaaaattcga tgatttcatc atccaagtct agatatgaaa agacttcctc acctggaacg
    48061 gcattttctg gcaaaatttg aataccatct gcgaatttct taggtacaac tgagtcagaa
    48121 atacccaatt caccaagtga acagatcatt ccaagtgact ctaagccacg gatttttcct
    48181 tttttgattt tgtaattgtc agcgatacga gctcccggaa gagccaccat aaccttgatg
    48241 cctgcacgca catttggggc accacaaacg atctgacgct cttcttcttc gccaacgtta
    48301 acctgacaaa catgaaggtg agtttctggc acatcttcgc aggacaagat ctcaccgacg
    48361 acaatttttg aaagaccggc agctggtgat tcgacacctt cgacctcgat ccctgtggtt
    48421 gacatttttt cagccaactc ctgtgatggc acatcaatgc ccaccaattc ttttaaccat
    48481 ttataagata caagcataat ttagttctcc agaatgacca ttgccacact ggttcttttc
    48541 ctttcctatc atttcaatag aagaattctc ttcttacctt aatttctttc tcagtaacca
    48601 atccgtatct actttttgac caaccataaa atgatgttgg ctaaattttt caaaaccata
    48661 tcggttataa aacgcttgag cttttgtatt atgctcccaa acacctagcc aagcccaaga
    48721 aaaactattt tttgtagcaa gttcaagtgc gaattcaaac agttgcttac ctagtccaaa
    48781 tccttggaat ttttgtagca catagaggcg ttgaatttca aaagcgtcct ctaattctct
    48841 ctcagtttga gcacttcccc agttgacttt gagaaaacca gctatctcct cctcatgcat
    48901 aatgaaatag gtttcagagt caggatttcc caactcagtt gacaaagttt tcagactata
    48961 agcctcttca aagtattcct gtaactgctc ttccgtatta tcatacgcaa aggtttcacg
    49021 aaaggcttgt ttggcaattt tagccaacac ctcaacatct gccatttcta cttttctaat
    49081 cattatttaa actgttctga gaagcggaca tctccttggt agaatccacg gatatcgttg
    49141 attccataac ggagcatagc tacacgctct tgtccaagac caaaggcaaa gccagagtat
    49201 acagtcgcat cgataccact catttcaagg acacgtgggt gaaccatacc ggcccccata
    49261 atttcgatcc aacctgtttt cttacatacg ttacagcctt ctccaccaca tttgaagcaa
    49321 gaaacatcca cctcaacaga tggctctgtg aatggaaagt aagatggacg caaacgaatt
    49381 tgacgctctt caccaaacat tttttggaca atcaactgaa gcgttccttg aagatcagcc
    49441 atagagatat ttttcccaac taccaagcct tcgatttggt ggaattggtg actgtgggtc
    49501 gcatcgtccg tatcgcgacg gaagacacgc cctggcgaga tcatcttcaa aggaccttta
    49561 gaaaaatcat gggcatccat agcacgcgcc tgaactggag acgtgtgggt acggagcaag
    49621 atttcttcag tgatatagaa agtatcctgc atatcacgag ctgggtggtc ttttggaagg
    49681 ttcatacgtt caaagttata gtagtcttgc tccacttcaa aaccatccac gacttgataa
    49741 cccataccga tgaagatatc ttcgatttct tcactggttt gtgtcaaaac gtgatggtga
    49801 ccagtcgcaa ctggacgacc tggaagcgtc acatcgatac tctcgctagc cagttgagcc
    49861 gcgactttct tttcttccaa gagcttagct gtttcttcaa aagcagcagt caagacatca
    49921 cgagcttcat tgacgtgttt cccgatgatt ggacgcatct cagcagaaac atctttcatc
    49981 cctttgagga tttcagtgag cgaacccttt ttaccaagga cagagacacg caaatcttgc
    50041 atctcttttt catttccagc agtaatctgc ttcaagctag ccagcgtttc ttcgcgaagc
    50101 gcttttaatt gttcttcaat agttgacata tttcctccat cagtctctcg tagataaaaa
    50161 gaaaaccaca tgccaaaaac tccactcgga gcgttgacac gcggtaccat ccgttttcat
    50221 ctgacaagtc agaccttcat ttctaaatcc atgcgcaagt gaattcaccc agctttcata
    50281 tagagagctt gcagtcacgg ctctcctccc tgatatactt cccttgggct actagtcttt
    50341 cagattccta ttcaattact acttagttta tcagattttt accattcttg caagacctat
    50401 cttacttctg cttgttagct tattcttatc taactttata gcggattgaa ataagatgaa
    50461 aacaaatcga ttgggaaagt aaaatta
//
LOCUS       DAVLIK010000011        50122 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLIK010000011 DAVLIK010000000
VERSION     DAVLIK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.011"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            648..2663
                     /locus_tag="VXE87_000663"
     CDS             648..2663
                     /locus_tag="VXE87_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0842250.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLTTSTEWHDY
                     SPNGNVLIVTPHYLERQNIPVDTTIKQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            2665..3297
                     /locus_tag="VXE87_000664"
     CDS             2665..3297
                     /locus_tag="VXE87_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842251.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4225..4638)
                     /gene="ndk"
                     /locus_tag="VXE87_000665"
     CDS             complement(4225..4638)
                     /gene="ndk"
                     /locus_tag="VXE87_000665"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0842252.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEESLPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(4749..8426)
                     /gene="rpoC"
                     /locus_tag="VXE87_000666"
     CDS             complement(4749..8426)
                     /gene="rpoC"
                     /locus_tag="VXE87_000666"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0842253.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYIHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLLYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8459..12070)
                     /gene="rpoB"
                     /locus_tag="VXE87_000667"
     CDS             complement(8459..12070)
                     /gene="rpoB"
                     /locus_tag="VXE87_000667"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0842254.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12486..12556
                     /locus_tag="VXE87_000668"
     tRNA            12486..12556
                     /locus_tag="VXE87_000668"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12518..12520,aa:Cys,seq:gca)
     gene            complement(12754..14085)
                     /locus_tag="VXE87_000669"
     CDS             complement(12754..14085)
                     /locus_tag="VXE87_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0842255.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14376..15200)
                     /gene="endA"
                     /locus_tag="VXE87_000670"
     CDS             complement(14376..15200)
                     /gene="endA"
                     /locus_tag="VXE87_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0842256.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15239..15427)
                     /locus_tag="VXE87_000671"
     CDS             complement(15239..15427)
                     /locus_tag="VXE87_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0842257.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15420..16703)
                     /gene="murA"
                     /locus_tag="VXE87_000672"
     CDS             complement(15420..16703)
                     /gene="murA"
                     /locus_tag="VXE87_000672"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0842258.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKVSQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16727..16957)
                     /locus_tag="VXE87_000673"
     CDS             complement(16727..16957)
                     /locus_tag="VXE87_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0842259.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17015..18052)
                     /locus_tag="VXE87_000674"
     CDS             complement(17015..18052)
                     /locus_tag="VXE87_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0842260.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18036..18524)
                     /gene="coaD"
                     /locus_tag="VXE87_000675"
     CDS             complement(18036..18524)
                     /gene="coaD"
                     /locus_tag="VXE87_000675"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0842261.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(18514..19053)
                     /gene="rsmD"
                     /locus_tag="VXE87_000676"
     CDS             complement(18514..19053)
                     /gene="rsmD"
                     /locus_tag="VXE87_000676"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0842262.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19118..20110)
                     /locus_tag="VXE87_000677"
     CDS             complement(19118..20110)
                     /locus_tag="VXE87_000677"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0842263.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20222..20905)
                     /locus_tag="VXE87_000678"
     CDS             complement(20222..20905)
                     /locus_tag="VXE87_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0842264.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(20961..21701)
                     /locus_tag="VXE87_000679"
     CDS             complement(20961..21701)
                     /locus_tag="VXE87_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0842265.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFYLS"
     gene            21735..22013
                     /locus_tag="VXE87_000680"
     CDS             21735..22013
                     /locus_tag="VXE87_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0842266.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYYDFKIAN"
     gene            22091..23017
                     /gene="yidC"
                     /locus_tag="VXE87_000681"
     CDS             22091..23017
                     /gene="yidC"
                     /locus_tag="VXE87_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0842267.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23199..23993)
                     /gene="pflA"
                     /locus_tag="VXE87_000682"
     CDS             complement(23199..23993)
                     /gene="pflA"
                     /locus_tag="VXE87_000682"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0842268.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(24119..25369)
                     /locus_tag="VXE87_000683"
     CDS             complement(24119..25369)
                     /locus_tag="VXE87_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0842269.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTPAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25436..26263)
                     /gene="purR"
                     /locus_tag="VXE87_000684"
     CDS             complement(25436..26263)
                     /gene="purR"
                     /locus_tag="VXE87_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0842270.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26530..27471)
                     /locus_tag="VXE87_000685"
     CDS             complement(26530..27471)
                     /locus_tag="VXE87_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0842271.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(27461..28717)
                     /locus_tag="VXE87_000686"
     CDS             complement(27461..28717)
                     /locus_tag="VXE87_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0842272.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28719..29381)
                     /locus_tag="VXE87_000687"
     CDS             complement(28719..29381)
                     /locus_tag="VXE87_000687"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0842273.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29344..30000)
                     /locus_tag="VXE87_000688"
     CDS             complement(29344..30000)
                     /locus_tag="VXE87_000688"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0842274.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(30011..30889)
                     /gene="rsgA"
                     /locus_tag="VXE87_000689"
     CDS             complement(30011..30889)
                     /gene="rsgA"
                     /locus_tag="VXE87_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0842275.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(30891..31763)
                     /gene="rsmA"
                     /locus_tag="VXE87_000690"
     CDS             complement(30891..31763)
                     /gene="rsmA"
                     /locus_tag="VXE87_000690"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0842276.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(31894..32202)
                     /locus_tag="VXE87_000691"
     CDS             complement(31894..32202)
                     /locus_tag="VXE87_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842277.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32195..32836)
                     /locus_tag="VXE87_000692"
     CDS             complement(32195..32836)
                     /locus_tag="VXE87_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842278.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32838..34868)
                     /locus_tag="VXE87_000693"
     CDS             complement(32838..34868)
                     /locus_tag="VXE87_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0842279.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFIDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(34945..35241)
                     /locus_tag="VXE87_000694"
     CDS             complement(34945..35241)
                     /locus_tag="VXE87_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0842280.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(35561..36460)
                     /locus_tag="VXE87_000695"
     CDS             complement(35561..36460)
                     /locus_tag="VXE87_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842281.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(36532..37092)
                     /gene="rnmV"
                     /locus_tag="VXE87_000696"
     CDS             complement(36532..37092)
                     /gene="rnmV"
                     /locus_tag="VXE87_000696"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0842282.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(37092..37865)
                     /locus_tag="VXE87_000697"
     CDS             complement(37092..37865)
                     /locus_tag="VXE87_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0842283.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALKLVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(38170..39063)
                     /locus_tag="VXE87_000698"
                     /pseudo
     CDS             complement(38170..39063)
                     /locus_tag="VXE87_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
     gene            complement(39347..39481)
                     /gene="rpmH"
                     /locus_tag="VXE87_000699"
     CDS             complement(39347..39481)
                     /gene="rpmH"
                     /locus_tag="VXE87_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0842284.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(39626..40840)
                     /locus_tag="VXE87_000700"
     CDS             complement(39626..40840)
                     /locus_tag="VXE87_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0842285.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(40996..41290)
                     /locus_tag="VXE87_000701"
                     /pseudo
     CDS             complement(40996..41290)
                     /locus_tag="VXE87_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            41452..41904
                     /locus_tag="VXE87_000702"
     CDS             41452..41904
                     /locus_tag="VXE87_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0842286.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(41939..43327)
                     /locus_tag="VXE87_000703"
     CDS             complement(41939..43327)
                     /locus_tag="VXE87_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0842287.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            43393..44355
                     /locus_tag="VXE87_000704"
     CDS             43393..44355
                     /locus_tag="VXE87_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0842288.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPYIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(44384..44677)
                     /locus_tag="VXE87_000705"
     CDS             complement(44384..44677)
                     /locus_tag="VXE87_000705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842289.1"
                     /translation="MNTIERTRRLIKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDETNEVSSKHVFEVVDETNEVSSKHVFEVVDETDEVSNHTYGKAT"
     gene            complement(44741..45751)
                     /gene="ccpA"
                     /locus_tag="VXE87_000706"
     CDS             complement(44741..45751)
                     /gene="ccpA"
                     /locus_tag="VXE87_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0842290.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(46176..46775)
                     /locus_tag="VXE87_000707"
     CDS             complement(46176..46775)
                     /locus_tag="VXE87_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0842291.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLMLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERNIADLMQTLHTVLEGRKEYSPELMEVVMMHPNPLTEQEIAVLKGIAQGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(46776..47873)
                     /locus_tag="VXE87_000708"
     CDS             complement(46776..47873)
                     /locus_tag="VXE87_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0842292.1"
                     /translation="MLERLKRIHYMFWISLIFMIFPILSVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKSSLTQEL
                     ESTASMILLELVTNIIKHAKASKVYLKLERTEKELILTVRDDGCGFASISGDELHTVR
                     NRVFPFSGEVSVISQKHPTEVQVRLLYKERK"
     gene            complement(47873..48610)
                     /locus_tag="VXE87_000709"
     CDS             complement(47873..48610)
                     /locus_tag="VXE87_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842293.1"
                     /translation="MKRWLALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTGFSMMSTAIFSFPAVLHTDKMNNWQKILRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLILGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPVSLFPDWMQAIGKRLPSYQLMELIKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(48612..49496)
                     /locus_tag="VXE87_000710"
     CDS             complement(48612..49496)
                     /locus_tag="VXE87_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842294.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEVDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLVQAGCGIQEIEV
                     NNRSLLDTIFEETQKGDN"
     gene            complement(49483..49677)
                     /locus_tag="VXE87_000711"
     CDS             complement(49483..49677)
                     /locus_tag="VXE87_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842295.1"
                     /translation="MKKGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(49674..49880)
                     /locus_tag="VXE87_000712"
                     /pseudo
     CDS             complement(49674..49880)
                     /locus_tag="VXE87_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        14425 a        11432 c         9541 g        14724 t
ORIGIN      
        1 acaaggaaaa agaaaagggt ttcacgaatg aagaaaaatc gtggaattca aaaattagct
       61 atattagtat tactaggtgt ttttatgttt agtaacacaa ttccttacca acagtttatt
      121 cagaagaata gacaattgga gattcgagtg caatcacaaa agaagtccaa tggtcttgat
      181 gttgtgaagg ctgattgatt tcgtattact ttaaaattca actatttaga gaaaggtatt
      241 ctgatgagag cttgtaacaa taccagatag atataagaat ggagatgttt gataaaatgc
      301 tttcatagct aaccaactgt tgaaaattat gagttacaaa atctaaagta tttaagattg
      361 gtttataaaa ttaggtctct gcctgtagaa aggaacgtgc agttagaaag gaggaaaaaa
      421 taggatacta taattcagac tgagatttct aattaaaata tgtagttgca tttcgctcat
      481 tttcataata tttcattcag aggagtaata atatgttaaa atttagattt gatgcgggat
      541 ggtaaagaat aattgaagaa gattctttta tcaatagttt agtaagcttg ttagtttata
      601 gagggcaggg gtatttctgc cctctgtttt agaataagga atgcactatg aaaaaattat
      661 ttatactcat atccaacctg cttgctagtt tgttctttgt ttgggtattt accatttgga
      721 ctgatacata tgtctcctat tattacccca acgttgttgt acatgattct tcccctgaaa
      781 caacttttca gcatgttgct acacgcttgg aaaaactagc agaagaaaca gatagcttta
      841 ttgcgattca acaccaagat cctaactcag aaggtactac agttttttct tatacgacct
      901 ttggggacgg aaagttgcct gatgggcttc aggaaaaaaa tctagaagat gctcaaagta
      961 gtagtgttga aacaaactat tttgtattcg atggacacct agatattcac ttgctaaggg
     1021 aagagctaag tcaacttggc ttgactaaca tgcacctgac aattccatct aaactatcta
     1081 cgttaatggc tatctttagt aacggatttc agttaatcag tctattgatt ttcatcttaa
     1141 cctttgtagc actgacttta attagtcaaa ttagccaatt acggtcatcg ggcattcgcc
     1201 tcatttcagg agagaaacgg tggtccattt tccttagacc agttggtgag gatttgaaag
     1261 ggatagctgt tggtttcagt ttagctggcg tgctcgccat tcttatgcaa aaaattctgt
     1321 cgcttccaac gcaatcccta atgaccatag gagcaggctt gctcagttat aatctcatct
     1381 tgttgtcgat ctccctgttt ttcgctcaac tcttcgcagt tgggataaaa aagatacacc
     1441 tgatgcagat tataaaaggg caagtgcctg tcagaggaat cattagtttg attttaatcg
     1501 gtcaactgtt agcgattatt attgtaacgc tgggaatagg gagtagctta aagtattccc
     1561 aagcctggca acagcatcgg attggacaag aggtttggag tcaggaaaga caactgatta
     1621 ccctatcaat cagccgtgaa ggaacgagtc ctggttttga tgaacaagct caaaggaaac
     1681 tcagaacttg gtatcaattg atggatctgg ctgtttcaga acaaaaggct ttcttatcta
     1741 gacaccagtt aattgaccgt actttgcaaa atggcatggc ttcctccaaa aacttgacaa
     1801 cctctacaga atggcacgat tacagcccga atggcaatgt ccttatcgtc acaccgcatt
     1861 acttggagcg tcaaaacatt cctgtagata caactattaa gcaaaagatg aatcacctta
     1921 atgtagggga gtttgtctta ttgctgcctg aacacctccg ttcagaggaa gaacattata
     1981 aatctgtttt tgaagacgac ttaaccagtc gcatgtctag tcaagatgaa cgacagcaaa
     2041 tgactgctac ggtaggttat ttagaatcag gtcaggatcg ttttgtgtat aatacgaccc
     2101 ctatttctta ccagcagttt ttgaaagatc caatcatcat tgttataaca ccccaatcaa
     2161 ctggtccaca gtccattttg ttttggatag acgcagtaca gaactacgtt ctctttaatc
     2221 aattgtctga tgcccaggag cttatccaga gacaaggcat tgaaaattgg gtctcagaaa
     2281 tgcaaacagg ttaccacaac tacatcacat tattggataa tatccagagg gaacgttggg
     2341 taatgctagc aggagctgtg cttgggattg caacttcaat cttgttgttt aacactatga
     2401 ataggctcta ctttgaagaa tttagacgtg ccatttttat caaacgcatt gcaggtctca
     2461 ggttcttaga aatccatcgc acttatctct ttgctcaact gggtgtgttt ttactgggat
     2521 ttgttgcgag tgtatttctt caggtagaga taggagttgc tttcttagtc ttgttactct
     2581 ttactggtct atctctttta cagttacatg tccaaatgca gaaagaaaac aagatgtcca
     2641 ttcttgtttt gaagggaggt taatatgatt gaacttaaac aggtgagtaa atcttttgga
     2701 gaacgagagt tattttcgaa tctttcaatg acatttgagg ctggaaaagt ctatgcctta
     2761 attggttcaa gtggtagcgg aaaaacaacc ttgatgaaca tgattgggaa attagaacct
     2821 tatgatggga cgatttttta ccgaggtaaa gacttggcca attataaatc gagtgatttt
     2881 ttccgtcacg aattgggcta cctcttccag aactttggct taattgaaaa ccaaagtatt
     2941 gaagaaaacc ttaagctagg tctcattggt caaaagttga gtcggtcgga acagcggttg
     3001 aggcagaagc aggctttaga acaggtcggc ctggcttatc ttgacctaga taagcgcatc
     3061 tttgagttat cgggcggaga atcgcaacgg gttgccttgg caaaaattat cttaaagaat
     3121 ccacccttta ttctggcaga tgagccaaca gcttcaatag acccagcaac ctctcagttg
     3181 attatggaga ttttgctatc tcttcgagat gataataggc taatcattat cgcaacacat
     3241 aatccggcaa tttgggagat ggctgatgaa gtgttcacga tggatcatct gaaataaaaa
     3301 tccttgtttt taattgcacg atgagttact gaaatattat catgaatcaa taattggagt
     3361 taatttagaa ttgtacttta ttaatattga ggtaactttt tcttgataaa ggaagaaata
     3421 atggagagga agttagaatg aaaaaattcg acaattatat tattgagaag ccttgcgatt
     3481 ctaattcaga taaactgcaa aaaatcttaa taattgaaag tttggtagat gatattttgc
     3541 aattttctct cagaatcaat aatagtgtag gagagatttt cctcctacaa ccgttttaaa
     3601 agaaaactat ctttattcca tgttattttg aggaagatat tgtgaaagtc aaagatgatg
     3661 ataaagttga gtggaatttg ttagaatttc aaaaatttag agcatttttg gcttagtaat
     3721 ctgtgttgaa ggctcaaaac ctatggtaaa aaagtcgctt tgaaaacgta ttgcctccaa
     3781 agatttagtt aaataatgat ttaacacaaa aagaaattat tgaagttctg gaaagatgtt
     3841 gtttcagtat tgagaaaagg tgggaaaaac ttgcgatttt cacagagaaa ggaagaaaaa
     3901 gtatagaaat atagtcaatt gaaacaagaa caggacaaaa gaaccttttg tgccatattt
     3961 ttctcctttc gctttacaat tggcttgaac acctttattg tatcgcgttt ggagtttttt
     4021 tggtataacc ttcgacgcgc acccgcatag cgggtgtttt tttgtctcgc acctaacgga
     4081 gcgagacgaa ctaatagtca cttaatcaaa aaacgcacca tatcaaaaac taaaaagttt
     4141 gatatcatgc gtcatgtctt aaactaattg actatacttt ctattcaaat gagcttttaa
     4201 ccaattgatt gagccaatcc actcttaaaa ccaaagagca atttctcgct tagctgactc
     4261 ttctgaatct gaaccatgta caacattttg gataacctca ttttctccag cagcttttgc
     4321 aaagtcacct cgaatagtgc ctggtaaaga ttcttctgga cgagttgcac ccatcatggt
     4381 ccgccaagtt tcgattactt tgggaccaga aatgacaccc acaagaactg gacctgaagt
     4441 catgaattca cgaatcggta ggtaaaaact ctgaccaacc aagtcctgat agtgctggtc
     4501 aatcaactct tctgaaacct gtgaacgaaa ctccaatttt tcgattgtaa atccacgttg
     4561 ttcgatgcgc tttaacactt cacccactag ccctcttttt acaccatctg gtttgatgat
     4621 aaagaatgtt tgttccatac ccgtctcctt tgtcagcttc tttcttttat tttaccacat
     4681 ttcgtggaaa aatggagaaa gttttcagaa gagagaatga gagaacccga gggttctctc
     4741 attctctctt attctactgt ttcttccaca gtttcaacgg cagtatccac aactacttct
     4801 gttgtttctt catttccttc ttcctctact ggaggattaa ggtattcttc ttcgttgaca
     4861 gcatgtggtt caaggttacg gtaacgggcc ataccagtac cagctgggat gatcttaccg
     4921 atgataacat tttctttaag tccaaggaga tggtctttct taccacggat agctgcgtca
     4981 gtaaggacac gagttgtttc ttggaaggaa gctgctgaca agaaactgtt tgtttcaagt
     5041 gaggctttgg taattcccat aaggactggg cgacctgtcg ctggaactcc acctgcgata
     5101 aggacatctt tgttggcatc tgtaaagtca ttgatatcca tgagggtacc catgagaaga
     5161 tctgtatcac ctggatccat gacacggact ttacggatca tttgacgaac cattacctcg
     5221 atgtgtttgt caccgatttc taccccttgg ctacggtaaa ctttttgtac ttcaccgaga
     5281 aggtacgttt caactgacaa gacatcacga actgcaagga gacgttttgg ttggatagaa
     5341 ccttctgtca gagcagcacc acgcgctact tggcccccaa cttcgacacg catacgagct
     5401 gtaaatggaa cgacatattc accttcgcca gtttcaccct taacaaagac tttcttggta
     5461 cgagttgatg catcttcttc gatagcagta acttgtcctt taacctctgt gataaccgct
     5521 tcccctttag gattacgggc ttcaaagatt tcttggacac gaggaagacc ctgagtgata
     5581 tcggtatttg aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg tgtaccaggt
     5641 tccccgatag attgggcagc aattgtacca actgcttcac caacttcaac cgcatcacca
     5701 gtcgccaagt tgataccgta acagtgacgg cagacaccgt gacgagtgtt acatgtaaat
     5761 acagaacgga tagtcacttc ttccacacca gcattgacaa tttcacgcgc cttgtcttct
     5821 gtaatcaatt catttggacc aataatcact gcaccagttt ctggatgttt aacagttttc
     5881 ttagtgtaac gaccgttgag acgctcttcg agagactcga tcatctcttt tccttctgcg
     5941 atagaacgga tcaagagacc acggtcagtt ccacagtcgt cctcacggat gataacgtct
     6001 tgggcaacgt cgaccaaacg acgagtcaag taacctgagt cggctgtctt aagggccgta
     6061 tcggtcatac ctttacgagc accgtgagtt gagaagaaca tttccaatac cgacaaacct
     6121 tcgcggaagt ttgaaaggat tggcaattcc atgatacgtc cattcggagc agccatcaga
     6181 ccacgcatac cggcaagctg tgagaagttt gagatgttac cacgggctcc agagtccatc
     6241 atcataacga ttgggttctt aggatcttgg ttagcaatca agcgtttctc aagtttttca
     6301 cgggcagcac gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt gatcatacca
     6361 cgacggaatt gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat gatttcagtc
     6421 ttgtcatcaa cgactgggat atcggcaata cccactgtca atcctgcaag agttgagtgg
     6481 tggtaaccga ggttcttcat gcggtcaagt agggcagaag tttctgtcgt acggaaacgt
     6541 ttgaagattt cagcgatgat atttccaagg tttttcttct tgaatggagg gttgagctca
     6601 agattgctga tagcttcctt gatatctcca ccaagtggca agaagtattt agctggaaca
     6661 ccttctgtca agttggcatt gtttggttct tgcaagtata gtagcccctc tggcatgata
     6721 tcgttgaaga gaattttacc aactgttgta agcaagacct tatgtctttg ctcttctgtc
     6781 caaggcttgt tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg aatataacca
     6841 ttgcggtaag ccataaccgc ttcgtcacgg tctttgaaga ccattccttc accttcgcga
     6901 ccagcttctt ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga tggagtaact
     6961 accggtttcc catctttcgg gttcaagatg tgctcagcag ctagcatgag gatacgagct
     7021 tctgcttgtg cttcttctga aagtggtacg tggatggcca tttggtcccc gtcaaagtca
     7081 gcattgtagg cttcacagac aagtgggtgc aagcgaagag ccttaccatc aatcaagact
     7141 ggctcgaagg cttggatacc caaacggtga agggtcggtg cgcggttcaa aagcactggg
     7201 tgttctttaa tcacttcttc aaggatatcc cagatacgct catctccgcg ttccaccaag
     7261 cgtttagctg ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg catgacaaat
     7321 ggtttaaaga gttcaatcgc catttcacgc ggcacaccac attggtacat cttaagagtt
     7381 ggaccaacgg cgataacgga acgtcctgag aagtcaacac gtttaccgag caagttttga
     7441 cggaagcgtc cctgtttacc tttaagcatg tggctcaatg atttcaatgg acggctacct
     7501 ggtcctgtga ttggacgacc acgacgacca ttgtcaatca aagcgtcaac tgcttcttga
     7561 agcatacgct tctcattttg aacgatgata cctggggcat ttaactcaag caaacgagcc
     7621 aaacggttgt tacggttgat aacacggcgg taaaggtcat tcaagtcaga tgaggcaaaa
     7681 cggccaccat ccaactgcaa cattggacga agatctggtg ggataaccgg aaggatgtta
     7741 agaatcatcc attcaggttt gtttccagac ttgtaaaagg catccaaaac atccaaacga
     7801 cggatggctt tgacacgttt ttgtccagta gctgttttca attcttcttt gagttcagca
     7861 atttcttttt caagatctac ttgcttcaaa aggtcttgga tggcttccgc acccatcttg
     7921 gcaacaaatg aaccataacc atattcacgc aagcgctctc ggtattcgcg ctctgtcatg
     7981 atagacttgt gctcaagtgg tgtatcctta ggatcaatca ccacataagc cgcaaagtag
     8041 ataacttcct cgagggcacg agggctcata tcaagggtca agcccatacg gcttggaatc
     8101 cccttgaagt accagatgtg agatacagga gctttcaact cgatatgtcc catacgctca
     8161 cgacgaactt tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat tcctctgtaa
     8221 cgaatgcgtt tgtacttacc acaagcacat tcccagtctt ttgtaggacc aaagatcact
     8281 tcatcaaaga gtccttcacg ttctggtttc aaggtacggt aattgattgt ttcaggtttt
     8341 ttgacttctc cataagacca tgaacggact ttacttggag aagctagggt gatttgcata
     8401 cttttaaaac gatttacatc aaccactatt tcttcccttt ctattctaag tgaactgctt
     8461 attcctgttc agcagcttct tctgttgctt ccgcttttgt tgctttctca gcttcttcag
     8521 cttcaaaggc tgctttagcc tcttgggctg ctttttcgcg ggctttttca aggtcatcta
     8581 cgtggatgac atcttcgtcc attccttcat ccaagtcgcg aagttccact tcttggtcat
     8641 cttcgtctag aacacgcatg tcaagaccaa gagattgcaa ttctttgaca agaactcgga
     8701 aggattctgg aacacctggt tttggaattg gtttgccttt tgtaatagct tcataggctt
     8761 tcaaacgtcc gttgatatcg tccgacttgt aagtcaagat ttcttgaagg acatttgacg
     8821 caccgtaggc ttcaagagcc caaacctcca tctcaccgaa acgttgtcca ccaaactgag
     8881 ctttacctcc gagtggttgt tgggtaacag ttgagtaagg tccgactgaa cgcgcgtgca
     8941 atttatcatc aaccatgtgg tggagtttga tcatgtacat gactccaaca gaaacacggt
     9001 tatcaaatgg ttcacctgta cgtccatcgt aaaggattgt cttggcatcg ctatccatac
     9061 ctgcttcttt aacagttgac caaagatctt cagaacttgc tccatcaaag actggtgtcg
     9121 caatgtgaat accaagagta cgagctgcca taccaaggtg aagctccata acctgaccga
     9181 tattcatacg tgatggcacc ccaagtgggt tcaacatgat gtcgactgga gttccgtctg
     9241 gaaggtaagg catgtcttct acaggaacga tacgagagac aacccctttg tttccgtgac
     9301 gtccggccat tttatctccg accttaatct tacgtttttg agcgatgtaa acacgaacca
     9361 acatgttaac acctgattgc aactcatctc catttacacg tgtaaagatc ttaacatcac
     9421 gaacgacacc atcggcaccg tgtggtacac gaagagaagt atcacgcact tcacgagact
     9481 tgtctccaaa gatagcgtgc aagagacgtt cttcagctga aagatctttc tcacccttag
     9541 gtgttacttt acctacaaga atatcacctt ctttaacctc agcaccaata cggataatcc
     9601 ccatttcgtc aaggtctttg agggcatctt caccaacgtt tggaatttcg cgagtgattt
     9661 cttcaggccc aagctttgta tcgcgcgttt ctgattcgta ttcttcaagg tgaacagatg
     9721 tgtagacatc gtccttcacc aagcgttcgc tcatgataac ggcatcctcg aagttgtaac
     9781 cttcccaagt catgtaggca acgattgggt tttgtccaag cgccatttct ccattttcca
     9841 tagaaggtcc gtcagcgatg aaatcgcctt tttcaacgac atcaccaact tttacgagag
     9901 tgcgttggtt gtaagcagta cctgagtttg aacgacggaa tttttggatg tggtaaacat
     9961 ccaatgaacc atcttcacga cgaacttcta ccttgtcagc atctgcgtaa gtaactttac
    10021 catcatactg agcaatcaca gccgcaccag aatcgtgggc tgcttggtat tccataccag
    10081 taccaacgta aggtgcctga ggattaatca atggcacagc ctgacgttgc atattggctc
    10141 ccatgagggc acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg
    10201 caactacctg ttttggtgaa acgtccatgt agtcaacaat attagctgga tactcttggt
    10261 tgaccccttg gtgacgtccc atgacaatct tctcagcaaa ggttccatct tcattcagac
    10321 gagagttagc ctgagctaca gtatattcat cttcttcatc agctgtcaac caaacaattt
    10381 cgttcgtgac aacacctgtt tcacggtcaa ccttacggta tggtgtttga acaaaaccat
    10441 atttgttcaa gtgtccgtaa gatgacaagt tattgatcaa accgatgtta ggtccttcag
    10501 gtgtctcgat tggacacata cgaccatagt gagtgtagtg cacgtcacgc acttcatatc
    10561 cggcacggtc acgagtcaaa ccaccaggtc ctaaggctga caaacggcgt ttgtgagaca
    10621 actcagaaag cgggttgtgt tggtccatga actgtgacaa ctgtgatgaa ccaaagaatt
    10681 ctttaactgc agctgttaca ggacgaatat tgataatttg ttgtggtgtc aagacttcat
    10741 tgtcctgaac agacatacgt tcacggacat tacgttccat acgagaaagt cccaaacgta
    10801 cttggttggc aagcaattca ccaaccgcac ggatacgacg atttccaagg tggtcgatat
    10861 catctacacg gccaagtcct tcagccaagt tgaggaagta gctcatctca gcaaggatat
    10921 ctgcaggagt caccgtacga accttgtcat ctgggttagc attaccaatg atcgttacga
    10981 cgcgatctgg atcagttgga gcaataacct tgaatttttg aagaacaaca ggctcagtca
    11041 caacggctgc atcgtttggg atgtagacaa tcttgttcaa gtcgccatcc aaatggcttt
    11101 caatgctttc aatcacgcta cgagtcataa tcgtaccagc ttctaccaag atttctccag
    11161 tttcagggtc taccaatggc tctgcaatgg tttggttgag caaacgtgtt ttaacattga
    11221 gttttttatt gattttgtaa cgaccaactg ctgccaagtc ataacgacgt gggtcaaaga
    11281 agcgagctac aagcaagcta cgtgagcttt cagccgtctt aggctcacct ggacgaaggc
    11341 gttcgtaaat ttctttcaag gcttcgtctg tacgagagtc cattggattc ttgtggatat
    11401 ctttttcaac agtgttgcga accaattcgc tgtctccaaa gatatcaaag atttcatcat
    11461 cacctgagaa accaagagca cgaaccaagg ttgtaaatgg aatcttacga gtacggtcga
    11521 tacgagtgta ggtgatatct tttgagtcgc tttcaagttc caaccaagct ccacggttag
    11581 ggataacagt tgaaccatag cccaccttac catttttgtc tactttgtcg ttaaagtaaa
    11641 cacctggtga gcggaccaac tgagaaacga taatacgttc accaccattg atgatgaaag
    11701 tacccatttc tgtcatgatt gggaaatcac caaagaaaac ttcttgggtc ttgatttcgc
    11761 ctgtttcttt attgatcaaa cggaaggtta caaaaattgg tgctgagtag ctagcatcgt
    11821 ggatacgagc ttcttctagc gtgtattttg gttccttgat ttcatatcca acaaattcca
    11881 actccattgt gtctgtgaag tttgaaattg gcaatacatc ttcaaacact tccttaagac
    11941 cgtggtctag gaaagctttg aatgagtcag tttgaatttc aatcaaattt ggtaagtcaa
    12001 gaacttcttt gattcttgaa aaactacgac gggtacgatg tttcccgtat tgaacgtcat
    12061 gtcctgccaa gatgattctc ctttgtaaat aagttccaag ccttgtcaat caggcttttc
    12121 taatcgtcat atggttgtaa accccttatc accgtgtcct cttgacgaat tttcagaatc
    12181 tttaagcctc tgttacaaat gctcataatc ttgaaaaaaa gcacaaaaag agcagctaaa
    12241 tctgactttt tcagaagatt taactgctgt gagccttgtc tggacaatat ttcagacaaa
    12301 acctacgaca aatgattacc catattatac cctatttagc tagatttttc aaggggtttc
    12361 agtaggtttt tggtaaattt tttcccatag aaaacttggc atcacattcg aatcacgcta
    12421 tggtacaaaa aactgaaaaa actattgact gaaaatcatt ttcaaggtat aataataaac
    12481 gttaaggcgg tatagccaag tggtaaggca cggctctgca aaagcttgat cgtcggttca
    12541 aatccgtcta ccgccttcta taacttgatt tatcaggttt caaatgaaca gaaagcccaa
    12601 tttgaagggc tttttttatt ttccctcgaa taaatacgta taactttaaa aacttttgga
    12661 gcgagtttgt ggcagagttc tttccatggc ataattccct tttgaaatca attgaaaaaa
    12721 gcttcgtcac gcctggtgac aaaagcctct agtttattct gtttcttctt ctatttcgac
    12781 ttctgtgatt tggactttta ccttggtaac acgtccattc ttcactttat cattggttaa
    12841 gataaactgt ttgttttggc tgaccaattc atagctgagt ttctcagtcg ttggaatggt
    12901 tcccactcct gtcaaataat aaccagcgat ggtatcaacg tcatcacttt ccagctcaac
    12961 atcaaagtaa ttattgaaat cattgagggt catagttcct tgaacaatgt aggtatcctc
    13021 gccaatctga tgaacatcta ttgctgcttt gtccgtttca tcatcaattt caccaacaat
    13081 ttcctctaag aggtcttcca aagtcactaa accagccata ccaccgtatt catccagcaa
    13141 gattgccatt tgtctttggg tatttcgcag ttcttttagc aagtcatcca caaaaatagt
    13201 ttcaggtaca aaaagtggat cttgtaaaat tctcttccaa acaatattgt caaaaccgtc
    13261 cacaaagcct gccttaagga gactcttggt gtgaatgatt ccaattacat tgtccttatc
    13321 cccatcataa accgggatac gagaataatt ttgttttaaa atactttgga taatggcttg
    13381 actatcatcc tgaatatcca ccataaaggc atctgttcga ggaaccataa cctctcgtgc
    13441 catcagttca tcgagcgaaa agacaccttg tagcatctca atctcatcag catccaatgt
    13501 ttcttcacta tttgtcagca tataggcaat ttcatcacgg gtcatttttt catccgcatc
    13561 atcgaatgac ataggagtca aatggctcaa gaaattggtc gaagcagcta aaagccaaac
    13621 aaaaggactg actagttttc cgatcccaat gataaccggc gctgtacgaa ttgccaaggc
    13681 atcctttaga ttaagagcga ttctcttagg atataattcc ccaaaaacga tggaaatata
    13741 ggtcaaaaat gccaaggata gaaaagttgc cacggcttgt gctgtttcgc cattcccaag
    13801 ccaagaggca atcacacgtc ctagagtatc agttaaactc gcccctgata agattgtaat
    13861 cagggtgatt cctacctgaa tggttgataa aaagtggtta ggattttcta gtaccttcag
    13921 caggcggatg tagcgtctgt ctccttcttc cgccttttgt tcaactcggg cacgattaag
    13981 agaaaccatg gccatttctg tggctgagaa aaaggcattt aataccgtca agataaacaa
    14041 taaaacaaat tgtagcaaca aattctgact acttgggtct tccatagttc ttctcctaaa
    14101 atagtatctt atcccttatt atatcacaaa atttaatcca atacatatta tttttttctt
    14161 agcgtaactt ccatctctct cccaaaactg gaagttaggc taagacggat ttccactgat
    14221 ttcacgcgtt tttctcatac taaaagctag gttgtgggaa actggaagtt agttttagaa
    14281 gttactattt tttcttagta cctgttctaa ccctgcttaa actagtaaaa agaactccta
    14341 catccataag tgacatagga gtttaggctt atcttttact gagttacagt tacttctcca
    14401 gttcggtaat ccagttgaag tcccttttga acattgggaa ctagaacatt gaattccaat
    14461 tctccatccg aagacttggc ttcaatctgt gaagctgagg gaactaaatc ctcgtttgaa
    14521 gcgtagtaaa gggttacacg gtaacggaca cgcttgtttt ggtccaaggc tttacgcacc
    14581 ttgctttcat agtagttttg accagtcgaa tactcggctt gtgcctgatt tgcccaggct
    14641 gtctgaacag caatgttttt aggattgctt gttgaggcat caaaaccatc caaaccaccg
    14701 attaaggcat agcctaacaa atgacctcta tcgactgcat gggtataaga gccctttaga
    14761 ttcttgacct gatgccaacc tggaggagtc caagaagttg aaccattccc agtttcttta
    14821 cgattcttgt actgacgagt ggccttagac aagagggcat tagctacggt tggaacagtt
    14881 tccttgccca ctgtctttgt tttattgtca gcgtagggct tacttgaaac cttggcatct
    14941 agatttgttt tattaccatt gacgataaaa gcacctgagc cattccactc cagactcccc
    15001 tttatttgac tcttgactgc gtctgttaag acactctctg ccaatgcttg actaggagct
    15061 tcagacgctt gttttttctg actaagcttg gttttaggac tattagctgt cgactgcatc
    15121 tgcttgatat aatagctccc tgtagacaaa agcaataaca ctagcagtcc gattagtgtc
    15181 tgtcttgttt ttttgttcat atttctcctt atctttagaa aaaggctggt tctccagcct
    15241 aatttcctgt aaatttatga atcaattcct gccattttgc tggagacagg atagcccatg
    15301 gatcttgacc cttgcccaag attccataac ctaccattaa accgattcct agagccagag
    15361 tacctaaaat cagtactatg atgactaaaa gtaaacgctt gactacgtag cttgatttct
    15421 tattcatctt catcacttgc ctcaatccgc tgaatcttag cacctagctg cgccaacttc
    15481 tcatggaaac cgtagtaacc tctatccaag tgaaccaatt taccgaccac agtttctccc
    15541 tgtgctacca aacctgtcaa aatcaaggcc gcactggcac gaaggtcagt tgaaagaact
    15601 tctgctccct gcaaaggctg tccaccaaca atacgagctg tatcacggat aatctcagaa
    15661 tgcaagccca tgcggcgcat ctcttctagg tgttggaaac gattttcaaa aactgtctcc
    15721 accatggttg attcgccttt tgcaactgtc atcaaggctg taaattgagc ctgcatatct
    15781 gttggaaatc ctgggtgggg caaggttttc acatgaacag cttttagatt ttccagttga
    15841 gaacgaacac gaattccttc gtcttcttca attacttcaa cacccatttc aagtaacttg
    15901 gcaatcaagg gacggttgtg ctcccagaca gcgtctcgaa tcaagacatc accaccagtc
    15961 atggcagcag ctaccataaa ggttcctgct tcgatacggt cctggactac attgtgagtc
    16021 gtaccatgaa gtttctcaac accagtaatg gttatagtct ctgtaccagc acctttgacc
    16081 ttggctccca tttcattaag gagaatggct aagtcaacaa tctcaggctc acgcgcagca
    16141 ttctcaatca ctgtcacccc atcagccaga gtcgctgcca tcatcaagtt ctgcgttgca
    16201 ccaacacttg gaaagtccat atagatatga gcgccatgca agcgttctgc cttggcttcg
    16261 atgtaaccag ctgtctgact aaccttaacc cccatagctt ccagaccttt caaatgaaga
    16321 tcaataggac ggctaccaat cgtacaacca cctggcatgg ataccttggc atgacccaca
    16381 cgggcaagga ttggccctaa tacaacgatg gaggcgcgca tcttgctgac atacttgtaa
    16441 ggggcttcct cagtgatgtc gccagtagca tccaccttga caagatgagc ttcctcatca
    16501 aagtcaacct tggcattcaa accaccaact acctgattca taataaagac atccgacaaa
    16561 atcggaacat tctgcaagac ggtctttcct tcacttgcta gaatagtcgc tgccaacaag
    16621 ggtaagactg cattttttgc tccctcgatc gtcacgcttc ctaccagacg attatcgcca
    16681 ccttgaacca caattttatc catactcgtt tcctttactc ttgattttat aataatcctc
    16741 taagcgcttc ttgccacaaa tgatacaggc taataaagaa agaactcagg atgtagccta
    16801 tgacaatgct aaaaaaggct actaataaac gaacttttct tgtattctca gctgtcactt
    16861 ttaaaacctt ttcccatcta acaagatcct ttaaaaggta aaaactcaca taaataaaga
    16921 gcatatgact acttagagtg aataataatt gaaccatttg actattatac catcttctct
    16981 gtttgtgcgc tagtttggaa acttcactca aaaattaggg attgtttttc aagtaatcaa
    17041 tcgcatcttg tagggtttta acgggcacga ttttcatatc cgtcttgatt gttttagccg
    17101 cttctagggc tgtttggtag ttgtttttcg cgtccggatg cgccttttgt tcttcttcgc
    17161 taacagggtt atcaggagca aagaaaatag cagcacctgc cctagccgaa gctacaacct
    17221 tcttatcaat acctccaatg tctcccacat taccatcgcg gtcaatggta cctgtaccgg
    17281 caacaatacg accattacga agatctgggt gagctatttg agtatagata gctagactaa
    17341 acatgagacc agcacttgga ccgccaatac cagctgttga aaagctaatt gggacattgc
    17401 tgattacctc tgtacggtca atcaagtcga ttccaattcc atttttgcca ttttccaagg
    17461 tgataatctt tccttctgca gacttggttt gcccatcctc ttcataggtg accttgacgg
    17521 agtcccctaa tttttgagaa ctgacgtaat caatcaagtc tttggaacta tcaaaggtct
    17581 gatcattgac tgctgtgact gtatcagaga tattgagaat ccctttaaag gttgaattat
    17641 ccgtcacatt caaaacataa actccaaagt acttgagttc gatttcctta ccagctgttt
    17701 ttagtccttg atacttggcc atattttgcg atgtttgcat gtagaattga ttgattcgca
    17761 taaattcaac atcggaagaa ccacctgtag tctcctgagc actacgaata tctgtaaaag
    17821 gtgtcaacca agcataaatc atatgagcta aagtagcatg ttgaacacca accgtaacga
    17881 attgataggc accagcttcc ttatcttctg tgtcatttac tttaaggact tggcgaatat
    17941 cttccgaacc acctggaacc tctatatagt agggcaaagg caccacaaat gccaagaagg
    18001 tcacaatcaa ggccgcaatg acatacaaag gccatctaat cttttttttc atttcttatt
    18061 tcctccaaaa tactctcggg aacatggcag gcaatatcct gaccaaactt caaaagctct
    18121 cgaacacctg atgaactgat atagagatgt tcaggccggc tatgtaaata aatagtctct
    18181 atatcagaag acagctgatg attgtagtaa tcaaaactag cttcatattg caaatccgcc
    18241 gcattcctca acccccgtac tagaaaagta gcccccagtc tttttgcaac atcgaccacc
    18301 aatttatcat gagaagccac gacttcaaca ttttccaaat gtcccaaagc cttttctagc
    18361 ccccgtttac gattttcaag agggagaaat ccttgtttgt ggggattaaa aaaaataccc
    18421 acataaagct tatcaaaaag tctgctcgcc cgttcaatga tatccagatg cccatttgtc
    18481 atcggatcaa atgagcctgt gaataagcca atcttatctg acatagactg tcaccttact
    18541 aattccataa atcttttcct tccagatacc cagacaggca atttcttctg gaagttcaac
    18601 ggctttatcc gtctcgcaca caaccataac atcttcagaa aaaagctctc tctcagccat
    18661 tttttcaata tctgctacga tttgttcctt ggcataggga gggtctaaga aaacgaggtc
    18721 aaattcccca gatacctgtt ccaatgccct ttctgcatcc atctttagga gttgaaattt
    18781 tccaacttcc ttggtcatct ggatattttc agccacgatg gtctgagcct tacggtctcg
    18841 ctccaccaaa acagcactgg acatgccacg cgatactgct tcgatagata aaccaccact
    18901 acctgcataa aggtccaaga ctcgtcccac ttcaaagtag ggaccaatca tgttaaaaat
    18961 ggctccccta accttatccg aagtaggtct tgtcgtcttg ccttctagtg tcttgagggg
    19021 acgtccccca tagattcctg atacgatttt catactgttt attataccaa attatagaca
    19081 aaaagagaaa gaaaaccgaa ccttgcggtt cgattctcta caaaatattt tcgtaagtat
    19141 cgcggacttc ttgaggccaa acacttgttt gcacttctcc gatgtgtctc ttgcgaagta
    19201 ggaacatggc catacgagat tgtccaattc ctccaccgat tgtcaatggg aatagaccat
    19261 tcaacaaaga cttgtgccat tccaattcca agcggtcttc atcacctgta atttccacct
    19321 gacgtctaag agtttcttca tctacacgaa ttcccataga agacaactca aaggctccac
    19381 ctaaagactc attccagaca agaatatcac catttagacc cttgtagcca ttctcagact
    19441 cgcttgtcca gtcatcatag tctggtgcac gtccatcgtg cggtttacca tctggcaact
    19501 cgccaccgat accaatcaaa aagacggctc caaattcttt acaaatcgca ttttcacgtt
    19561 ctttcggtgt caagtctggg tagcgttcta ccaattcttc tgtatggata aaggtgattt
    19621 gttttggcaa gatagactcg atgtcatagc gggcttcaac agctagctca gtcaggcgaa
    19681 tagccttata aatcttctca actgtttctt ttagataaac gatgttacgc ttaccatttg
    19741 ggataacctt ctcccagtcc cactggtcaa cataaacaga gtgggttgca tccaaggaat
    19801 cctcatctgg acgaagggct ttcatgtgga caaagagacc ctctccttca ccaaagccaa
    19861 aacgagccaa ggtgtggcgt ttccatttag caagtgagtg caccacttca taagtagcat
    19921 cagggatttg gagaaccttg accgatactg gattttccac accagacagg ttgtcctgca
    19981 ttccgtcacc gaccttactc aagataggac cttgaacttc gacaacttct agcttatctt
    20041 tcaaatactg ggtaaaagtg tttttgacaa aggaaatttc ttcttgttga tggataaaac
    20101 ttttcttcat agacaactcc tcaaaaattt aataaacgta ttatacacct atttccaaga
    20161 aaagaaaaga gaaaatttaa aaaaaatcag tgtcactcaa aacactgatt tcatagacct
    20221 tttagtcatt gcgaccaaag atacgtagaa tacttaggaa aagattgata aaatcaagat
    20281 agatgctgag agccattgac accacccagc ctgtcgctac acgaccttgt gattgttcat
    20341 aggcgaggcg aatcttttgg ttatcccaag caatcaaccc tgaaaaaacc aaaaccatgg
    20401 ctacgctaat catataatca aagaagccac tagccaagaa aatattgact accatagcaa
    20461 tcagtaaacc aatgagagct gccatcattg ctcgaccaat cccactcaag tctttcttgg
    20521 taaagatacc aactgccgcc atgacaaaga agagaagggc gctcgataca aaggcagata
    20581 aaactgtacc cggagtatag aaagccacca caaaactaag ggtaaagccg tttaaaacgg
    20641 agtaaagtaa aaatactgga agagcagctg gactatttct tgaagccatg ctactggcaa
    20701 cgaaaaccaa agccaactcc gcaaaagtag caatggtcaa ccagagacgc ccctgcatca
    20761 aaaagtaaac caactgagac tgaaaaaccg tcaacataag gcctgatacc aaagcagata
    20821 gtccgattcc cagaccaaca aaggcataaa ccttagcgta aaattgattg agacctgcac
    20881 ggtcatgtat aatagtgtga ttcatccatt tctccttttc tgtgaacatc tttccttgat
    20941 tataacaaaa aaagttaaaa ttagcttaaa tagaagatta aaataccggc tgcaaccgca
    21001 acattcaaac tctcggcctg ccccttcatg ctaatatgga ccaactggtc tgcactttca
    21061 gccataaggg gactaattcc ttgaccctca tttcccataa ctagtacaaa attttctata
    21121 gaaggcagtt ctctgtaatc aacagaatct ttagataggg ttgttgctag cactgggata
    21181 gctacctttt tagtttcgtc aagaagcgct tgactagtca tccggtaaat gggcagatgg
    21241 aaatgactac cttgcatgga acgtagggtt ttgagactgt agatgtctgc cgacttatct
    21301 gaaacaatca ctcctgtaaa acctgctgca tccgcagttc gaatgatagt tcctacatta
    21361 ccaggatctt gcacatcttc caaaaacaag aacttgccct gactcaaatc agcttgtcct
    21421 acttcttctt tttgaaccac ggcaacaatt ccctgtggag tctgagaatc cgccaaatct
    21481 agcaaaatat cctctgaaat ccagacagtt tgcggaaaag cagctaactg atttcgataa
    21541 ttttctaggg caaagatttt ctcaatcgtc actccagctt ggacagcttc ttcaaacaag
    21601 tgccagcctt caatcaaata ggcagacttg cggtattttt tttggtgtaa tttcttggca
    21661 ttttttacca cagaattggc ttttgaggtt ataatagtca tagaaatatt ataacacaat
    21721 caaaggggtt tggtatgcaa aaggttagaa tgattgccca aggtagggta cagggagtcg
    21781 gctttcgttg gggtgtttac agcttggcac ttgaaattgg tggcatcaca ggtcgagtat
    21841 ggaataacga cgatggcaca gtggaaatct tagcccaagc agactcatct gctatcatgg
    21901 caaaatttat ccaagaaatc cgaaaaggac cgacaccttt ttcaaaagta agctacttag
    21961 atgtcaaact aagcaacttt cctccctact atgactttaa aatcgcaaat taggtctcca
    22021 gaactattgt atattttgta aaaaaacagt agaatagaaa ggtataattt ttaaagaagg
    22081 aataaaaaca gtgaaatcta ttaaacgttt tgcactctcg gctatgggag tggctatgtt
    22141 gcttgtcttg actggctgtg tcaatgtcga taaaaccaca ggtcagccaa caggatttat
    22201 ttggaatacg atcggagcgc ctatggctga agctatcaag tacttcgcta ctgataaagg
    22261 tctaggcttt ggtgtcgcta tcatcatcgt aaccattatc gtgcgcttga ttatcttgcc
    22321 acttggtatc taccaatcat ggaaggcaac gcttcactct gaaaagatga acgctctcaa
    22381 gcatgtcctt gagccacacc aaacacgtct caaagaagca actactcaag aagaaaaact
    22441 cgaagcccaa caagccctct ttgccgctca aaaagagcac ggcatcagca tgtttggcgg
    22501 tgtaggatgt ttccctatcc tccttcaaat gcctttcttc tctgctatct actttgctgc
    22561 ccaacatact gaaggggttg ctcaagcaag ctacctaggc attcctctag gttctccaag
    22621 tatgattttg gttgcctgtg ctggtgtcct ttactatctt caatcgctcc tttcacttca
    22681 cggagtagaa gatgaaatgc aaagagaaca aatcaagaaa atgatttaca tgagcccact
    22741 catgatcgtc gtcttctccc tcttctcacc agctagtgtc acactttact gggttgtcgg
    22801 tggtttcatg atgattctcc aacagtttat cgtcaactat atcgttcgtc caaaacttcg
    22861 caaaaaagtc cgtgaagaac tagccaagaa cccaccaaaa gcaagtgctt tctctaaacc
    22921 aagtggacga aaagacgtta cccctgaaca accaactgct atcacaagca agaaaaaaca
    22981 caaaaatcgc aacgctggaa aacaacgttc gagataagaa gaaaaaggct tagctagttt
    23041 gctaagtctt ttttgcaagt catactcttc gaaaatcaaa ttcaaaccac gtcagcttcg
    23101 ccttgccgta ctcaagtaca gcctgcggct agcttcctag tttgctcttt gattttcatt
    23161 gagtatcaaa agcccgatgt ttccatcagg cttcttttct atccatgtac acgtttcata
    23221 taatcttgat aactttcggt atccatgagt tttttagcgt tcttgacgcg atctgctgtt
    23281 ggtggtttga ctccttcgag ggaatatgga attccaagtt cacgccactt gaactcaccc
    23341 atggtgtgat aaggtagaat ttcaaactta tcaacatttt tgagggtctt gacgaactta
    23401 ccaagttcaa tcaagtcatc atctctgtct gtcaatcctg gaactagcac gtggcgaatc
    23461 cagacaggtt ttccaatatc tgatagatac tgggcacaag ccaagatatt tttattagtt
    23521 tggctagtga caatcttgtg ctgttcttcg ttgatttcct tgatatccaa aagaaccaag
    23581 tcagtgacag ccatgagttt gtcaaacttc tcaaggtaac gtggtttatt acggaaagga
    23641 agagcacagg tatccaaggt acagtggatt ccttgttcct tagccttggt gaagagagca
    23701 atcaggaaat caatctgcaa gagagcttct cctccactga ctgtaatccc acccttattt
    23761 ccccagaaac cacggtagcg caaggcctct gtcaagacat catctaccgt ccgttcacgt
    23821 gacttattgg actccatagc ccaagtgtct gggttgtggc aatactggca acgcatgtga
    23881 cagccctgca aaaagacaat aaagcgaata ccaggcccat ctactgaccc aaagctttct
    23941 gtcgaatgca ccattcctgt cacttgtcca taatcaattg tttcttcaga catatcgtta
    24001 ccttccttga aaacgtttta tagttttatt atatcacgac ttgaaggaaa aacaagattt
    24061 ttgcctattt tttagaaagc aatctgtttt tcaatttcat tttcaatcta ttatcagatt
    24121 attcttcaaa atcgaagcca tataaggttg caaaatagtc ctcagggcgc tctgcacggc
    24181 ggatttgacg ggctttacct tcttcggtat agaggatttc cgcagaacgt aatttggcat
    24241 tatactggta gcccattgaa aatccgtggg cacctgtatc atgaattacc agcaaatcac
    24301 cgatttctgt atgaggcagt tcgcgattga ctgcaaattt atcattgttt tcacagagtg
    24361 aaccaaccac atctaccgct tcagctggtc catctggatg ggtcacgttg ctaatatgat
    24421 ggtaagctcc gtacatagct ggacgcatga ggttgactgc tgaggcatcc acacctagat
    24481 aggtacggta ggtttccttc ttatgagtca ctcttgtgac tagagcaccg tgaggtgcca
    24541 gcataaaacg acccaattcg gtgaaaatct tgacctgacc aagacctgct ggcgtaagga
    24601 cctcttcata caccttacga actccctcac caatcaaggc gatatcgttc ggctcctggt
    24661 ctggacgata attaacacca ataccgccag aaagattgat aaagtctagc caaatgccca
    24721 acttttcctt gatttcaaca gccagttcaa agagctgacg agccaactct ggataataga
    24781 gatgggtcac ggtattggac gctaggaagg agtgaagccc aaaagtcttg gctccttttt
    24841 ccttcaagat agcaaaggct tcaaagagct ggtccttggt catgccaaac ttagcctccc
    24901 caggattatc cataatgtct gtccccagtt caaaaacgcc tccaggatta taacgacaag
    24961 agatgatttc tggaatgcct gctactctct ccagatgttc aatatcttca aaggcatcca
    25021 agttaatggt cgcacccaat tcacgtgcat aggcgtattc cttgtctggc gtgttgttgg
    25081 aagagaacat aatctcagaa cccagaaagt ccagtttatg gctcatcaaa agctctacat
    25141 aactagagca gtccacacca caaccttctt cttggagaat tttcaaaata gctggagttg
    25201 gagtagcctt aactgcaaaa tattccttaa agcccttgtt ccacgaaaaa gcttggttga
    25261 cggctcttgc cttctcacga atccccttct catcatacaa gtgaaaggga gtcgggaact
    25321 cggcaacaat cgcttctaac tcttctctat tgataaatgg tgttttcata agcttccttc
    25381 tattctgttt gcaaagaaag gctgggacaa tcgttccaac ctttagttct atctcttatt
    25441 tatcttcgtc aaagatattg ccaacctcaa catcgatggc ttggttcttg acatcaatat
    25501 tggttacctt caagagtgac ttgtagtcaa actgcttttc acgttcttct tgggcattgt
    25561 ccgcaaagac cgctacacct gccagttctg agtcgaactc gcgcaagaga ctaatcatac
    25621 cattgaccgt tccgccacct ttcaagaagt catccacaat caagacacgg ctgcctgcct
    25681 taagactacg ttttgaaagg aacattttct cgatacggtc accacttgaa cctgaaacat
    25741 agttgacgct aacagttgaa ccttcggtaa ttttcaggtc acggcgcaca atgacaaaag
    25801 agacattgag gacattggca actgcatttg caagtggcac acccttagtt gctacggtca
    25861 taaccgcgtc aattttttgg tccataaagc ttttggcaat aatacgacca atatttttca
    25921 agatggctgg tgtgctaagc aaatcagaca gatagatata accacctggc aagatacggt
    25981 cactttctga caacttggta cgcaagtctt caaccatttc cttagcatcc tgactcgaaa
    26041 tagacggtgt gaagatgaca cctccgccag ccccagtcac tgtctggata tgaccgattt
    26101 caatttcctc aaaggcgcgt ttgataatga cgatatcttc tgagatggat gatttagcag
    26161 actcatactt ttcagcaaaa gtattgagac tagttagttt ataaggatta ttaatcaaat
    26221 agttggaaat gacaaccatc cgatcacttc ttcttaattt catttctatt tcctattcca
    26281 tttttattca aaaaatcaaa aagcaaacta gaaagctggt cgctggtggt tcaaaacact
    26341 gttttgagat tgtcaataga actgacaaac cctgtaatat acctgcatat atacatacga
    26401 caaggcgata ctaccctagt ttgaagagat tttcgaagag tattcatttt tgtcttttac
    26461 ttattatacc atattcacat aaaaaaacga acattcttat cctaaaaaat gctcattttt
    26521 cttaaattat taatctaaat ctggtttata gaaggaacga ttatccatag cgaagatttt
    26581 attggtcatc tctcctttat ccaccaaagc aagagctgtt gacatcatca tcatgcttgc
    26641 atccagattg tcaatcatat ggataatctc tgcttccata atgcgtggac ggactgggct
    26701 tccatactca agcaagccgt ggtgactgag gatgacatga cgaagcaaaa cgacttcttc
    26761 cttggtatca tcgatgccga gttccataac tgtcttggta atttcgctat caatgagagc
    26821 gatatgtcca agaagattac ctcgcactgt gtactctgtc tggtctggcc ccgtcaactc
    26881 gataacctta gctaagtcat gcagcataat ccccgcatag agtaagctct tattgagctg
    26941 aggataaact tcgctaatag cgtctgccaa acgtaccatg gtcgccgtat gataagccaa
    27001 gcccgtttca aaggcatggt ggttggtctt ggcagctgga taggagtaga attccttatc
    27061 atacttggtg tagagatttc ggacaatccg ttgccagaca ggattttcaa ttttgaaaat
    27121 catttgcgac atgtagtcac gaatttcctt gacatcaact ggtgacttga ccttgaaatc
    27181 ggctgggtca ttgggttcac cagcttgagg caggcggaga gtaatttgat tgacttgagg
    27241 ggtattgtta taaacttctc ggcgtccttt catgtggaca accttacctg cggtaaaggc
    27301 ctcaatgtta tgaggttggg catcccagag cttcccatca atctcgccac tatcatcttg
    27361 gaaggtaaag gctaggtagt ttttcccagc tcgagtttgc ctcaggtcag ctgatttgat
    27421 taggtaaaag ccttcaaata gctcatcttt tttcatgtga ctaatcttca tattcttcct
    27481 cattttcttg aaaatggagt agatcaagcg caggctcgcc ttctgacaac tcaatgtgac
    27541 ggagcgtccg ctcgatagct atggtacgac ggtttaataa ttcatcaata ttgccagagg
    27601 catgttggag atgtttttgt gccttgacca gaataccacc aaacttgcca aactcggtct
    27661 tgacactggc aagagtcttg ctgatatggt cggcactctt ttggatatta agggtcttga
    27721 aaccaactga tagggagtta agaagggctg atagggtact tggtcctgca acaataatct
    27781 gttcttcccg tctcaaatca tcaaagaaga ccggattgcg cacaatctct gaataaagac
    27841 cttctgtcgg aacaaacaag attccaaagt tggttgtccg aggcggtgct atgtacttgc
    27901 tcttgatatc cttggcaaag cgcttgacgc ttgctaggag tgacttacga cagcgttcaa
    27961 tctcatcctt gtcacctgtc tcataggctt cttccaagcg gtaataatct gccagtggaa
    28021 acttagagtc aattggcaga tagacgtatt cttggtcgcc ttgtccgggt aacttgatgg
    28081 catactccac tcgttcacta gagttttcaa ccgttgcgta ttctcgttcg tactgggcag
    28141 gtgtcatgat gtcttcaata atttgcccca gttgcaattc tcccagaatc cctcgcgtct
    28201 tggttccaga gagaaccttg ttaagagctc cgacatcacg ggcaactgtc tgcatttctc
    28261 caaggccacg attgacagac tccagttgtt tagaaactgt ctcaaaggaa gcctgtaagc
    28321 gtgtctgcaa ggtcttttct agtttttcct cgaccgtctg gcgcatttgt tccaaacgtt
    28381 gctcatttga ttcctgcaag gcttggagac gttggtctgt cttgtctcta gtttggagga
    28441 gattatctgt catttcttga cggacttggg tcagaccttg gtgcaattca atccgcactt
    28501 cttgcaaacg gtcgctgaca accacttcca aatctttttg gtctaactgg ctggcttgtc
    28561 tggcttggtc aaagcggtaa tccaactggt ctgacaaatg atctgcctga tcctccaagc
    28621 tcttacttaa gtgtttctcc tgcctatcct gcctttgcca aatcagaaaa agaccagcta
    28681 ggttggcaat taataataga ataagtaaac tttccatcct acctcctgtc cttgctatgc
    28741 agtacgacca cataaccatc tgggcaagtt accgacactt ccctatctat atattcgtta
    28801 gaagcgtaca cttttttaaa gaaaaaattc tcctctgtca actcatactt ggctccaaga
    28861 atagtcagct ggctatcccg aactggcata aaggctagat agtcgtagtc tgaacgaggt
    28921 tctagctgac tggtcccttc tgaacaatag gcaatcaaat tttgcccatc ctcaatttct
    28981 atttgacgca tatagggtgc caacttagga ttgctaggta gaaagacatt ggccaacata
    29041 tggtcaatac ggccacccaa ggcaccgaaa atagtgacct cagcctgagg attttgttca
    29101 aagatggtta agagagccaa ttccagatct gtatcatcct tttctggtcg tgcttggaca
    29161 aaatactggg cacgtttttg aatcacctgt cgctcttctt ccgtcacaga atcaaaatct
    29221 ccgactgcta gagcaagagg taagtcttct tccaagaccc agagcgagcc tcgatccacc
    29281 ccaacaaaag catcaaaatc tgtccgataa tgaccgcggt ttccgcctgc aaaaactgca
    29341 accctagtcc agttgttttc tgagagtttg tactcgctca ttgacttctc ccttaaagac
    29401 ataggaacct gctacaaaaa cagtcgcacc agcttctttg gcttgggcaa tagtttggtc
    29461 atcaatccca ccatccactt cgatttcaaa gttcaaacct ttttcctcac gaagagcaac
    29521 caactcacga accttatcca tggtttctgg cagaaaggct tgcccaccaa aacctggatt
    29581 aaccgtcatg actaaaactt ggtcaactag atgaaggacg tgcttgatgg cttcaactgg
    29641 tgtgccagga ttgataacga ctgaaggctt aactccgagt gaacgaattt tttggagggc
    29701 gccatgaata tgaggtgttg cttctacatg gatactgatg atgtctgcac ctgcacgcgc
    29761 aaaatcttcc agatgatgct cagggtttga caccatcaag tggcaatcga aaaccatctt
    29821 actatgagga cgaaggctct cgaccacacc tgcaccaaaa ctgatttgcg gtacaaaatg
    29881 actgtccatg atatcgatat gggcatattc tgccccagtt gcttctagac gtttgatttc
    29941 acgttcaaag ttggcataat ctgctgccag aattgacgga gcaatcttgt attgagacat
    30001 aggtttctcc ttattttgga atttttttgc tgactttttt ataggtttct ctacgatttt
    30061 caatttcgct gaggaattgc aggtagttgt caaaacggaa ggtggcaatg gtcccctctt
    30121 ctacagctgg cttgacggca caagacggct catgggtatg ggtacaagta cgaaacttac
    30181 aatctcggct gacagtagca atctctggga aagcctgatt gaggtcttca gcccttgata
    30241 cttcatagtc cagagatgaa aagcctggtg tgtctgcgat tttacccccg ttgagattgt
    30301 aaaaactaac agctcgagtg gtatggcgac cgcgacctag actgtctgaa atttctcccg
    30361 tttcaagatt gaggtctggt acgagtttat tgagaagagt tgacttccca acacctgtct
    30421 gccccataaa gaccgtaacc ttgcctgtta acaaagacag gagttcctct ttactggtca
    30481 caaagtcata gccgatgtca ccataggtct gccggtaaaa atccagttct cccctatctt
    30541 ccaacaaatc cattttggaa atatagacaa tgggatggat gcccttgtgc tccaaaagaa
    30601 ccaagaaacg atccagcaaa ttgctgttaa aatcaggttc cttgacggac atgattacta
    30661 cagcttgatc gatattgaca ataggcggac gaaccagact gtttttccgt tcgtgaattt
    30721 tgaggatata gccttctgaa ttttcctcgg cagagaaatc tacccagtcc ccaacataag
    30781 gggtatggcc ttttttacgg aaattcccac gcgcgcgtgt ttgataaacc tggccatcac
    30841 tctccacata gtagaaacct gccaaggctt taatgatttg tccctgcatc ttagagtcct
    30901 tgccctttaa gtgcgtctgc tagaccggca aattctgcca agctgagagc ttccccacgc
    30961 acacttggtg acaagcctgc ctggtccaaa gccttggtca gcttgtcctt gacctcttca
    31021 gtcttaccaa agtaacctgt caagttattc cacaaggtct tgcggcgatg ggtaaaacta
    31081 gccttggaaa ccttaaagaa aaagttctca tcttctactg ctacggctgg ctctggacga
    31141 cgcaccattt tcaagatggc tgaatccaca tttggcgctg gcacaaagac cgtacgaggc
    31201 acgataaagg caaccttggc tgtcatgtaa tactgcacgg cgatagacaa gctaccgtaa
    31261 gccttggtgt taggctgggc tgaaatgcgg tccgctactt ctttctgcat catgaccaca
    31321 aactcacaaa aaggaatgcc actctcaatc aagtgcatga gaataggcgt cgtgatgtag
    31381 taaggcaaat tagccactac cttgattggc aggtcaggat ttttaaaatt ctggatatgt
    31441 tgcgccaaat caaccttgag aatatcttcg ttaactacgg tcacattatc aaaatcacgc
    31501 agggtatctg ccaaaattgg caccaaacgg tggtcaatct caaaagccat gacttgggct
    31561 gcacgctcag ccaaaaattc tgtcaaggca ccaatacctg gcccgatttc gatgacattg
    31621 acctgatcat caatttcagc cgtatccaca attttttgaa ggatattggt atccgtcaaa
    31681 aaattttgcc caaaggactt tttaaaggta aaaccgtgac gctccagcac tgccttggtc
    31741 acgctataat ctgcaattct catctattct cttttctatt atctgttact actattgtaa
    31801 cacattcccc ttgtattttg ggaatgaaaa tcataccaaa aaactatctt tcctcatgaa
    31861 gaaagatagt cttggaaatc tttaaaagtg gccttagcag ttctctcgaa acatgcgttc
    31921 aaaaaaatca gcttcttgat aacttcgatt ttcaggtagg gtcaaatcca catcctcctc
    31981 cacatcatcc actgtcagtt caaccgtctg aggtaaattt ttcaaacgat aatgcttttg
    32041 cctttgccct tcaatactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa
    32101 aaggagatga ttggtcatat tttccatgat gaggatatct tctaaaccac ctctggcact
    32161 aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat
    32221 caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc
    32281 gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa
    32341 gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata gtcttagcaa
    32401 gggcaactcg ttgggcctct cccccagata aagtatagat tttttgttct aaatccaaat
    32461 accctagatt aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga
    32521 ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc
    32581 caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg ggaatggttt
    32641 ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc tttcccaaga
    32701 tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct
    32761 tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc
    32821 cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt
    32881 ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg
    32941 ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct
    33001 ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta
    33061 atcataagct cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag
    33121 atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc cacccgtttg
    33181 tcatttagta ccttggcaaa aaatagctgg ctttttacca agtaagaaac cttgtgatac
    33241 agaccttgct cttttagagc tgtgatgctg tctccatatc gatctagttt caaggcacta
    33301 ttagccgtag ttccccacaa catccctgca acaggtcttg ttccagtcgc ttgcggcgtt
    33361 agaactacaa taatcggatc ttttaggtac tggcgtgttg tcttgtaccc atcattatag
    33421 aggaaacgtt cctgtcctgt ttctgtaaaa gctagcctta cctgtgggaa gtagtgtttc
    33481 tgactcgtca cttctacact ttcagatgaa aagttttgca ggtaatctgt aaacaatcct
    33541 tggtagtagg cagactgctc ccgcaagctc tcaggcaaga tcagcccaaa ctctccctca
    33601 gacaagtttt gcatcttgtc aataaactct gaagaaacgg taatcttttc ttctatcaga
    33661 tagcgcggcg agacatagat aacattccct gacggtgtgt agtcactgag acgattgcca
    33721 tctaggtcca cttctgctcc atctgagaaa ttgtcaacat tgctcataat ataaaaagag
    33781 tctgtattgg ctaaccgttc ttcagtaaat gtctgccact cacgattatc cttacgcgtt
    33841 ccttcttcat cggcaaatgc actagaccaa ccaaaggata gacggtaacg gtctgaggac
    33901 tggctccatt tattgctagc tctctccatt tcctgcattt cacggtagtg gggtaggaga
    33961 gctgtcgcac tcgatccgac caccaataca gctaagagtt gccccaccat catcaatgtc
    34021 atcatccgtt tgagagggag tttccctttc aatagatcca ccagactatt ttcctgtaaa
    34081 ccaagtagat agacgacact tagtaaggta gaaatccctg ccagggtcaa tccataaagt
    34141 agaagagcaa tgatgaccag ttgcaccgtt gccataaaca aggcaccttg ataccagaga
    34201 atccccaatc ccaaaagact ggataccagc actgagcaga taagctgtct cacatcttct
    34261 aacactggtc tgagagcaac tccaaacaag ctctcaccag ctattaagcg aatccctgcc
    34321 tgacgaaggg atttgatccg ataaatcagg gtcagactca taaaggtcag cagaaaaata
    34381 gctaaactca gtagcaccat aggggtggcc gtcaatagta agactatcga aaatggatct
    34441 tctccattcg aaacaaagcc ttgataacca agctctttca aggtggtctg taagctcact
    34501 ccatccaaac ttcctgacac aatcaagtaa gaccctaata aatcactcgt ttctgcactc
    34561 tccttggagg aaatggtcag accttctgga agctttccct caccataagt ggcataggta
    34621 aagcgtgttt ctccagcttc atttggctca acaatccgac gggcgatgag actattatgc
    34681 tctaccgcca agtgactcaa agcctctgtc acctcttcgc ggctagctac tggttgattt
    34741 atcatcattc ctgtcacatc aacagaagga tagttaccaa ataaaatctc ttctcgatgg
    34801 tcaacggaag ttatcaccat ataaagcgat accaatacca ttgaaatcaa aataaataaa
    34861 cgtttcatca tttcctccaa aaagttactt ggtcacttag tgagaaggtg accaagtaaa
    34921 gctaaacaat agggctatac cattctaaac attatagtag aatgcaactt tctctcccca
    34981 agaagtacga atccatgcac gagaagtccc tccagcacca gcatatccct tgtcagatga
    35041 accagttttt ctgctaacaa ctgttgaact atggtatttt gaagggtgat agtagtttga
    35101 gtaagcacca ccgttacctg aaccataagt ccaaacacca ccttctgggt attgaacggc
    35161 tgcagaggca actgatacac ctccacctaa tgttgctgca atgctcgcta caagagctaa
    35221 ctttttaact gtttgtttca tattgatact cctctatttt tgattacaag attgttgagt
    35281 tacttgctcc tctttccatt atcaacgttg atactattat attaccaaat gatattctaa
    35341 aattatttgt ttttctctaa attgtcaaaa tagcaccctg aaatgaactt ttatagtcat
    35401 tatactccat ctttatcaca ctatcaagga catcaatgtc cttaaaatct aactatttca
    35461 tattattttt agcttatatc taaaaaaaca gttctaaaga cgaactttag aactgttttg
    35521 atacgaggac aaggacattt ttgtcactga ttcactatgt ttataaatat tttttgacat
    35581 cctcttgcca ttcctctgtc aatttcttta ctagaaattc atctccaatt agcttcgcaa
    35641 atgttttaga agactgataa aatgattcag ctaaactaaa atctctttct actcttaatg
    35701 cttgcttcca caaaaacata aatacaagag gtttcttttg ataatcttga gttttatcca
    35761 taatttcttg taaacacgat agataatcat taaaacaatc agttactcct accttttcaa
    35821 gacaacacat tcctgaaata agagtatctc taattataaa gtaattctct atttgagtta
    35881 ccttcttctg ttccaaaaga aagagcatta gcttttcgat ttgatttata aatttggcaa
    35941 gatcttttct aatgagcatt tgataaaaaa acaaacgaat caacaacata tcatttattg
    36001 aataagcttc tttttctata atctgaggca tatgttcctc aagtattaac tctgcatatt
    36061 caggccttct agttctagaa gtatccaaac acgcctgcaa tacttcacat gctaattgtt
    36121 cttctttagg aagattatca aagtatgttt tataaatctc ttccaaacac gcttccttct
    36181 tatcgtactc ctcttcttta ccatagattg gttcacgtaa aatctggtat ttcaattcta
    36241 aataagcaga aggaagagct gaaaaatccg gcataaggct ataaactgga actcctagcc
    36301 ggcgagcaat ataggctaac ttgggcaaac tcggttgcga agctccactt tcaattcgcg
    36361 acagttgacg aactgtcagt tcttgctcat ctccacaaaa atctggacga ctaattcctt
    36421 tttctatccg aatctcttta attttttgac caattaacat cagacgcctc ctcttctacc
    36481 tgcttcgaaa aatactgtga aacttaaaaa attgtaacgg ctacatcttt cctactcata
    36541 agatttcata gcttcttcca cttctgccaa agtaacccca aacaactcta ggcgtttgag
    36601 gagttgcttg ccgttagaat agccgattcg gagagtctct ccgagatatt ctctacgctt
    36661 acggctgtct gcccctgcta gaaaaccaag gcgaatcaag tcgctacgac taatgtcaaa
    36721 ctgactctca tgttcaaatt gttctgtcac ctgagctaga gccgttttca ggtcttcata
    36781 gctggcatgc tcaattccca gagaacgccc cttggtcttg gacttgggaa cagcttcatc
    36841 tcgcttgaga aaggcatgct gaactgttgg aatggccgtc ataatcatgc gccgaatccg
    36901 ctccccatta aaatctgggt ctgtaaagac aatgactcca tgacgttggt gtagacgctg
    36961 aatccgctct atgtcctggt cattgatggc agaacctcga gtctcatagg tctccacatc
    37021 gaaataacgc ttgagattga ccgtatcatc acgaccttca accacgataa cttgggaaat
    37081 tctctctttc attacttgct gtccaatcca aaaattcgtt ctgcatttgc agtcgttgct
    37141 accgccagct cttctgtcgt cataccacgc aagtcagcga taaagtcgac cacatagcga
    37201 gtataggctg ttttattttc acgaccacgc ttgggtacag gtgctaagta aggcgcatct
    37261 gtttccacca acatcttgtc caaaggtaac tctttagctg cttcttggag gtcagttgcc
    37321 ttcttgaaag tcaccactcc tgagaaggaa atggtcatac caagatccac aaacttctct
    37381 gcccactcaa gcgtccctga aaatgaatgc atgataccac cacgaggacc aacgccctca
    37441 ctcttgataa tctcataggt atcttccagc gcatcacggg tatggacaac aaaaggcaaa
    37501 tccaagtcct tagatagctg aatctgacgg cgaaaaacct gctcctgcac ctctttgggc
    37561 gctgtcatcc aatggtagtc taagccaatt tcacctaaag ccacaacctt ggaatgtttt
    37621 aacttatcca acaagtaagc ctcaacttcc tctgtataag taccagcttc tgtaggatgc
    37681 caaccaatag tcgcatagag ctgctcatac tcatctacca acttcaaggc atgctcaatc
    37741 gtcggtttat caaaaccaac aatattcatc tgtgtcacac ccatctcatc agccaaggca
    37801 atttcttctg cctcacgacc tgcaaattct tctacattca agtgtgtatg tgtatcaaaa
    37861 atcatctctt ctaacctcgt tttctatctt ctattatacc aaaaaagagg aggggcacct
    37921 aatttttcgg tttcccctcc tctcttcaat agagagctat tctgctatct tttctatccg
    37981 atattgccca tctcctgtcc cacagttaga gacagaagag attggctaca ttgatagaat
    38041 attcctattc agctaaagta tgtgattatc ttgggttctc acttttctca cccatcacta
    38101 ggattgataa cttctcaaaa tcccccttat aatctaactt taagtagaga atagaatttt
    38161 ctagctgttc tattttctac gtctagtctt tcttcctagc aaagcaaaac cacttgttgc
    38221 cgccgctaga ccaagactag caagtgctgc acttgatgct gaacctgtgt taggtaattg
    38281 tttgccagca ggtgactggt aggtaacatc ttgcattgtt cctgcagttg cttgcggtgt
    38341 acttgttgtc ttaggagcag cattaggagc cactggtctc ttaggaactg taaccatggc
    38401 aatggcttgc actccaatcg tttctgcttc cttcacatct tccatagttt tcgtattttc
    38461 aatctctttg agagctgctt gtttttctgc ttccactctt gctaaaagtt ctgctttttc
    38521 tttatcagaa agcggtgcgc ctttgatttc atcctgcttg tccttggctg ctttttcaat
    38581 ggcattttta gctgattctt tttcagtagc taattgctta gaagcttgtg attgagctga
    38641 gttttgtgaa cctgtgtgag ctgatccacc cgcctggcta ccaccgcctt cattcgcatt
    38701 agcatcttag cttccagtat tgcctccctt atctccacct ggtgtatttt ctagcttata
    38761 ctctggtgta gcttcttgag ttacagattc acctttcgca gattgttgaa ctgtatcttt
    38821 tcctagaatc gtcactactg aaccatctgg gaatgtgatt gttgctgtac catctccagc
    38881 tacattgatt gtcgctccgt ctaatgctga accatttgct tgtaaaatag caaccttaac
    38941 tttttcttca tctgttaaat gagttatatc ttttacatct actctttgag caggtgcttt
    39001 aacagttgat ttttcagcag tcagtttagt gctatcttgt gcttttggat cttgtgctac
    39061 caattgattt cctggaattg taatagctga accatcttta aagacgattg ttgctgtacc
    39121 atctccacct acttcaactt tatagtaaaa taaaataata acaggacaaa tcgatcagga
    39181 cagtcaaatc gatttctaac aatgttttag aaacagaggt gtactattct agtttcaatc
    39241 tactgtaaca tcgcttccga atccatttgc atctactgaa cttttttaca aaaataaaaa
    39301 tcagtagact cgagttccta ctgatttttg atagaattcg tttggattat gcagccaaaa
    39361 ctttgcgtcc tttacgacga cgagctgcca atacgcgacg accattttta gttgacatac
    39421 ggttacggaa tccgtgtttg cgcgcacgac gaagtttact tggttgataa gtacgtttca
    39481 cgatgaatac ctcctcatag attttgtatt cgtttagccg gctataaagt gatcagttac
    39541 taaacatact ttactattct atctgattct ttcacttttg tcaatagctc taggcaaatg
    39601 tttccagctt tttcgaatgc aagccctatc tacgatactg tttcaagaaa cgagtcatct
    39661 tttcttggat ttgggctaac tcatcaacac gaggaaggta aacgatacgg aagtggtctg
    39721 gttcctgcca gttaaagcct cgaccatgaa ccaagagaac cttttcctgc ttcaagaaat
    39781 caaggacaaa ctgctcatca tcatcgatac ggtacatatt gcggtcgatt tttgggaaga
    39841 tatagagccc cgccttgggt ttaacggcag acaaacctgg aatatcttga atggcattat
    39901 agatgaaatt tctttgctcg tagattcgtc caccaggaag aagcaattca tcgactgatt
    39961 ggtgaccccc caaggaagtt tgtacgactt gttgggccaa aacgttagag caaaggcgca
    40021 tattggacag catattgagc ccttcgatat agcccttaac atgagtctta gggccagaca
    40081 agaccatcca acccacacgg aaacctgcta tgcggtggga ttttgacaga ccattcatgc
    40141 tgacacagaa gacatctggt gccaagctcg ccacaggcgt atgcacatgt ccgtccatta
    40201 ccatgcggtc atagatttca tccgcaaaga taatcaaatc gttttgacgg gcaatctcaa
    40261 taatctccag caagagttcc ttaggataaa gggctccagt tgggttattt ggattgataa
    40321 ggacaattgc cttggtattg gaagtgattt ttgacttgat atcgtcaata tctgggtacc
    40381 attccacagc ttcatcacag atatagtgaa cggcatttcc tccagctagg ctgacagccg
    40441 ccgtccatag aggatagtct ggcattggca ctaagacctc atccccattg tccaaaagcc
    40501 cctgcatgga catgacaatc aactcactga caccatttcc aaggtaaata tcatcaatat
    40561 ctacgtttgg gaatttcttc agctggcaat actgcatgat ggccttacgg gctgagaaaa
    40621 tccctttgga gtcagaatag ccttcactat cacgcgcatt cataatcaag tcatgaatga
    40681 cctcgtctgg cgctgtaaag ccaaattctg ctggatttcc tgtattcaga cgtaaaatct
    40741 tttctccatt cgctcgcatc cgcatggctt cttccaatac aggaccacgg atatcataag
    40801 caacatgctc taacttacta gacttgttat attctttcat cttgtttcct caattcatca
    40861 ggatagtaac attataccac tagaaagaga atgcgacaag tttactgaaa tgtgttacta
    40921 gtttcgtata gaagaaaaac cttgctaaag gcgaggttaa gaacgtagag atagcaggta
    40981 ttttgcaaag acacatcaca taccaaaaga taaacctaga aaaaagcaag cctagaaagg
    41041 agtcataaag aagattaaac atgaggaaaa gcccccatat catcaagtaa tcccaacgcc
    41101 cacttcgttt tgcaactaga aataagatta gatggtagag tacatgaaaa actaaaaatc
    41161 caataaaact tggataaaga agcggtacca gactctctaa ttgacagatc atgatcactt
    41221 ctaccaagac tgaaactagg ataattccat aataaaggaa atttgatttt tgaaaagagt
    41281 ttttcatcat tctcccttcc ttcacttctt tcctgctatc ctttctttta ttttatcata
    41341 tatttatata gagtttaagc cctaatattc ttttgaaaaa tacttttttt gctttacttc
    41401 tatagtgaaa aggtttacaa ttatagtaag aaaatttcag gaggtttcat tatggcacaa
    41461 cgttaccaaa atatcatggt cgcaatcgat ggttctaagg aagcggactt ggcttttgtc
    41521 aagggagttc attctgctct acgaaacgac gctaaactca ccatcgcaca tgtcattgac
    41581 acacgcgctc tccaaagcgt atccaccttt gatgctgaag tttacgaaga actccaagtc
    41641 gacgctgaaa gtctgatgaa agagtacgaa aaacgtgcta aagatgctgg ggtagcagat
    41701 gttcatatcg tcattgaaat gggaaatcca aagaccctgc tagcacgtac tattccagat
    41761 gccgaggaag tggacctcat cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc
    41821 ttggtcggct cttcatctga atacatactc cgccatgcta aggtcgattt gctggttgtg
    41881 agagaacaag aaaaaacctt ataatcacaa agaaaaggag cccctagctc ctttttgttt
    41941 acgatttatt tctctcttta tggcgttcgt aagccttgag ctggcgctgc agttcctttt
    42001 taatagcagg ttctggagca tatttttctt cccaattatc tggttttaag attttatggg
    42061 tcactggatc aaaatgagcc ttgccatctg gaaaaatttt ccccatattg gcctgatgga
    42121 caatatcaaa aatacgttct gggtccaccc ccatcaagac aaaactgccg taggtgaagt
    42181 aaagcgtgtc aatcaaggca tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct
    42241 tggctacttt atctgctgcc ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa
    42301 aatcttcttc agaaggactg gctgctcgaa caaactccac caattcttct attttaaaac
    42361 cagccctatg ggttgcaccc tctaaatccc aagctcgagg ttcttcttgg gttcgttcat
    42421 ccatcatgtg gtggaaggtc ttgaccttat tgaaatgata gtcacggctg acaaagactt
    42481 tttctgaaga caaaacacca aaatgttcca aggccttgtg gattccatct tgttgattgc
    42541 tagtggtaat gtgcttggca gcttccttga cactgctact accatttccc atagcgaccg
    42601 acataccaac gccagccagc atttcaagat cattatctga gtcaccaaaa gccatgactt
    42661 ggttgaggtc aaagccatat tctttcccaa ctcggcgaat gccttctaat ttagaatttc
    42721 cctgattgat gacatccgat gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat
    42781 cagctgccgc cttctcagat tcttctggtg tcatcagcat caaaacttgg tagataggct
    42841 gattcatcag gtgaagcagg tcctcttcct tttggggaac aaccttgctg accatgcgat
    42901 taaaagactg actcaccgtc cgagttaaaa cagagggaac gaagcgacta attcgttggg
    42961 aaaaagaacc cagaccaaag gacatgattt tagaacccaa catggcatcc ttggtcccta
    43021 gagcaatctc cgtgccctct tttttagcat agctaattag atggcgcaaa tgtaacttgg
    43081 aaatagggct cgtgaacaag actctgtctt tactaaagat atactggcca ttataggtta
    43141 ccgcaaaatc cagatccaaa tcgtccatca attccttaac aaaaaaaggt cctcgccctg
    43201 tcgctacgcc aactagtacc ccttgttctt tgacaatctt aatcgcatcc ttagtggatt
    43261 tcaaaacact cttgcgattg ttgaccaagg ttccatcgat atcaaaaaaa acagctttga
    43321 cttccatcct atcccaatct ccccttttgt gatacaatga ttataccaca tttcagaaag
    43381 agtgagtaaa tcatgcctaa gaaaatcctt gttttacata cgggtggaac tatttccatg
    43441 caggccgatg cttctggcgc tgttgtgacg agttcagata atcccatgaa ccatgtgtcc
    43501 aacccacttg aaggaatcca agtccacgcc ttggactttt ttaaccttcc aagtccctat
    43561 atcaaaccca aacatatgct ggtcctctac cagaaaatta aagaggaagc agataactac
    43621 gatggagtgg tgatcacaca cggaaccgat actttagagg aaacagccta tttccttgat
    43681 accatggaag ttccccatat gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag
    43741 ctcggtagtg atggtgttta taattaccta agtgctttac gagtggccag cgatgacagg
    43801 gctgctgaca aaggagtttt ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc
    43861 accaaaacac atacgactaa tgtcagcacc ttccagactc caacacatgg cccccttggt
    43921 ctcatcatga aacaggaaat cctctacttc aaaacagctg aacctcgtgt tcgctttgac
    43981 cttgatcaca tacaaggttt agtccctatc atctcggctt atgctggtat gacagatgag
    44041 ctgattgata tgctggattt agaacacttg gacggtttga ttatccaagc cttcggagct
    44101 ggtaatattc ccaaagaaac ggctcaaaaa ttagaaagcc ttctgcaaaa aggaattcca
    44161 gtcgctctgg tatcacgatg ctttaacggt attgccgagc ctgtttatgc ataccagggt
    44221 gggggcgtac agttgcaaaa agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa
    44281 gctcgcttga aactcctcat cgccctcaat gccggactaa caggacaggc tttgaaagac
    44341 tatatggaag gctaatactc ttcgaaaatc tctgcaaacc acgtcacgtc gccttaccgt
    44401 atgtatggtt actgacttcg tcagtttcat ctacaacctc aaaaacatgt tttgagctga
    44461 cttcgttagt ttcatctaca acctcaaaaa catgttttga gctgacttcg ttagtttcat
    44521 ctacaacctc aaaaacatgt tttgagctga cttcgtcagt tctatctgca acctcaaagc
    44581 agtgctttga gctgacttcg tcagttctat ctacaacctc aaaacagtgt gttgcgcagc
    44641 ctttaatcag ccgcctagtc cgctctatgg tattcattaa gtcaacatct cttgtttaag
    44701 agcaccaaat caggaaatct tctcgattcc ctgatttttt ctatttacgt tttcgtgttg
    44761 agctacgttc tgtcaaacca tgaggtaaga gaacttcacg ttcttccaac tcttccttat
    44821 gcataatctt ggtcaacata cgcatactaa tggcaccaag gtcataaaga ggttgggcaa
    44881 tcgttgtcaa gtttggacgg gtaaagcgtg agatttgtga atcatcacta gtaataattt
    44941 caaaatcttc tggcacagaa acacccttat cagccaaacc gttcaagact cctgctgcca
    45001 actcatcacc tgtcacaact gctgcagttg catttgatga aatcaaacgc tctgctaagg
    45061 cgtaaccatc atcatagcta tatttagatt caaataccaa accctcacta taagtgattc
    45121 ctgctttttt caaggtttcc ttgtagccaa ctaaacgaac cttaccattg atgtcatcca
    45181 ctagcggacc gctaacgaaa gcaatacgct cattttcttt agcaaggtaa ctcactgcat
    45241 caattgttgc ttgcttatag tcaatattga cacttggcaa ctggtgctca acatcgacag
    45301 ttcctgcgag aacaatcgga gtacgtgaac gcgaaaattc tgagcgaatt ttatctgtca
    45361 agtgataccc catatagata atgccatcta cctgctttga aaagagggta ttgacaacag
    45421 aaacttcttt ctcgttatct tcatcgctat tagctaggac aatattgtac ttgtacattt
    45481 ctgcaatatc atcaatcccc ttagccaaac tcgaaaaata accattggta atatttggaa
    45541 tcacgacacc gacagtggtt gtctttttac ttgcaagacc acgcgcaact gcatttggac
    45601 gataatccaa acgatcaatt acctctagca cttttttacg ggtattctct tttacatttt
    45661 tattgccatt gaccacacgg ctgaccgtcg ccatggaaac acctgcttca cgagcgacat
    45721 cataaatggt tactgtatca tctgcattca ttccttttcc tgtcctttct atctcacaca
    45781 ttcttttaca agtagaggta ctgattgaag ctctatatct acttacaaaa gtgaagatgt
    45841 gaaaatttcg ttttcatatt tctacttatt ccattctatc actaattgta aacactttca
    45901 agtgtttttt gaagattgat tgaaaaaatt tcatagaaaa cctaggttta gctccttgct
    45961 accaccttag actaaacaaa aaggaggaaa ctaagccctc ctaaagttat agtaaaatga
    46021 aataagaaca ggataaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag
    46081 tagaggtgta ctattctagt ttcaatctac tataggtatt gttccattca ctaccgtcaa
    46141 ttttagcaca tagtcttcat gaaaatatta tatcatcata accaaccaga ttctttcgcg
    46201 atattagctg cctctgttcg attacctgca tctagtttcg aaagaatatt ggtgacatag
    46261 tttcggactg ttccgttgga tagataaagt ttgtctgcaa tttcttggtt agagaagccc
    46321 tgagcaattc cctttaaaac tgcgatttct tgctccgtta atggattggg atgcatcatc
    46381 accacttcca tcaattcagg cgaatactcc ttgcgtcctt cgaggacggt gtgcaaggtt
    46441 tgcatgaggt ctgcaatgtt tctttctttt aatacataag catctactcc agccttgacc
    46501 gcacgttcaa aatacccagg acgcttgaag gtcgtcacca caaccacctt tgtttcaagc
    46561 ttttctgctc gtatccactc caagacttca agacctgtct taacaggcat ttctacgtca
    46621 aggatggcga tatctacaga ctccttttct aatagttgga ttgcttcttg cccattcttg
    46681 gcttgaaaga cagactctac atccggttga agcatgagca actggcacat ggcatctcgc
    46741 aacatacttt gatcttctgc gactaatact ttcatctact ttctctcctt ataaagtagt
    46801 cgaacctgca cttcagttgg atgtttctga ctgattacac ttacttctcc tgaaaatgga
    46861 aaaacacgat ttcggactgt atggagctca tccccgctta tagaggcaaa gccacagcca
    46921 tcatctctca ctgttagaat gagttctttc tctgtccgtt ctaatttcaa gtagacttta
    46981 gacgctttag catgtttgat gatattggtc actaattcaa gcaaaatcat ggaagccgtt
    47041 gactccaatt cctgagttaa gctagacttg tccaagtgat tctcaacttg aacctcaatt
    47101 ccagcaattt ctaacatctt tttcacagtc tctagttcgg atgtcaaagt tctagactta
    47161 agattttcca caatggttcg cacttcattc atggaatcct tgctgatctg gtgaatttct
    47221 tttaattcct tttccacctg tggataagcc tccatctgaa ataactgcaa ggctaaatct
    47281 gtcttgacac tcagcatagc aaaggtatgt cccagactat catgcaaatc ctgaccgata
    47341 cgactacgtt cattttcagc aagcaataga tttatctgag cattttgctt gacctgagct
    47401 tctttcaaat cctcgacaat acgaatccga accaatccaa aagtcattaa atcgacaaaa
    47461 gtaagaatta caagtagata gaatagaaac tcaacttcga ttctctgaaa aatcaacagt
    47521 tgccccacaa caaggacttg agcaagaaga aaagtccaga catgtaaaga ctttaaacta
    47581 cgtacgctga aatgataact taagagattg gataggaaaa agaaaaacca gatataatta
    47641 acagcaacaa aggcagtatt cccaactaca taagtcagca tgaggcccca atatagccaa
    47701 gataggcgct ggctcttagt tgttaaaaca cccaaatatg ccactacaaa tagaatatca
    47761 atcaataaat gccaggcaga aagccaccca gtcactacag acaggatggg gaaaatcata
    47821 aaaattaaac tgatccaaaa catataatgt attcttttca gtctttcaag cattaagcat
    47881 tctccttatg accttgaagg taaatagtca aaccaaataa aactgctgaa aaaacaagta
    47941 gataaactgt ggctgataga ttgattccac cctcatttaa gaaggtcttg attaattcca
    48001 tcaactgata acttggtaaa cgcttcccga ttgcttgcat ccagtctgga aataaagaga
    48061 cgggcatcca gagtccgcct aaaacagcca atcctagata aagaagattg cccacgacag
    48121 acatcagctg actagttggt aacagcgtca aggttaagcc aagtgctaca aaagcaatac
    48181 ttcccaaaat cagcaaaatc gcagctccaa cccattttac tagaggcatg tctacacctc
    48241 ttacaaaatg tccaactgta aaaacaacca gaattgagac caaataatca accagcatac
    48301 ttgttatctt tgatagataa tattctacca tatttactgg gctatgacgt aatattttct
    48361 gccagttgtt catcttgtcg gtatgtaaga cagctgggaa tgaaaagata gcggtcgaca
    48421 tcatggaaaa gccagtcatg gagatgaggt aatcacgcat aaaattcgcg ggtccacctg
    48481 gtgtgtcctg gtacatgcca gaaaagaata gatagaaggc tgtcggcatc cctactgaca
    48541 atagataata gatcaattgt cgtttggtca ataaaaattc tatcttacta agtgctagcc
    48601 atcgtttcat cttagttatc tcccttctgc gtttcttcaa agattgtatc caacaaacta
    48661 cgattattaa cttcaatttc ttgtatgcca catcctgctt gaactaacag ttcccaaaaa
    48721 gcatctgctt cgcgtgtgac tacttgtaga gcatcctgtt tttgtgacca gttttcaacc
    48781 aagttagact gctcaatgac ttccttgtat gccagaggaa ggataaaatg cttttcaatt
    48841 ccctcactac gcatagctag aggcgtcgta tcacgaatca actctccctt atttaagagc
    48901 aaaatgcggt ctgcagtgtg ttccacttcc tcaatataat gggacgaata gagaatggtg
    48961 actccttgcg cttttaactc ctggacaatt tcccaaaaac gttgacgagt tgaggtatcc
    49021 atggacgcag taggctcatc taaaaaaaca atctttggtc gcccaattaa ggtcaagacg
    49081 aaagaaaaga gacgcttttg accgcctgat aatttttctg ccaactgttc tttttgttgc
    49141 ttgacaaact gcaatagttg atcaacttcc tgattgctca aaggatttgg atagatacgt
    49201 tgaaagaaag caatcaactc tttaactttt aatttctgaa cgattacatt ttcttgaggg
    49261 aggtaagccc tagtatagtc taacttagaa ctcgtcactg gtaaaccttg aatagatact
    49321 tgaccgcttg tgaccagttt atctccaagc aaacaatcta agagtgttgt ctttccggca
    49381 ccatttggac caattaaggc aacacattca ccatcgttga tttcaaagga gatgttccgc
    49441 aaaatttcct tgtcttttat tttcttactc aatttttcaa ctttaaccac agtcatgaga
    49501 ctctcctttc aaccactcca ttcccatagg gaaaacgacg aaaatcataa atccaaaccc
    49561 caaagcacca cgaatgaatt ggcgaagcaa ggcttgatca aaccaatcag taaacatttc
    49621 cactaaccat accaagagtg acaggccgat aaagaaatag atgatccctt tcttcattcc
    49681 tcaaactcct ttttcacatc tctgactaat ttcaaacctt ctctaacaag ccaagacatg
    49741 attccaaagc cagcaaagat ctttcaagga aaatggtaga aatcctcatc caatcccgaa
    49801 aacatgagat aggtcataac tcctgctact actaaactta ctgcgataat cattttattt
    49861 ctcatctctt cttcccccat ttcatactac aattatagtc ttttaaaatc agaggaggca
    49921 gaagcttctg tcactagaaa atatgacaaa tgtcataaaa aattctgttc aaaacaagca
    49981 agatacacta tacaataaaa cacaatcaga aaaatctaag gcaacttcct caaaagagat
    50041 atcaaaccca attcacacca taatgtaaac taatacttat ttaaaatcaa aaagagtaga
    50101 aatttttatc agacaaacac at
//
LOCUS       DAVLIK010000012        48084 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLIK010000012 DAVLIK010000000
VERSION     DAVLIK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48084
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.012"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            213..356
                     /locus_tag="VXE87_000713"
     CDS             213..356
                     /locus_tag="VXE87_000713"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842296.1"
                     /translation="MADRTDEVSSKHRFEVADRTDEVSSKHCFEVADRTDEVSNIYTA
                     RRS"
     gene            complement(710..1690)
                     /locus_tag="VXE87_000714"
     CDS             complement(710..1690)
                     /locus_tag="VXE87_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0842297.1"
                     /translation="MKNSALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(2017..2220)
                     /locus_tag="VXE87_000715"
     CDS             complement(2017..2220)
                     /locus_tag="VXE87_000715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842298.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHCFEVADRTDEVS
                     SKHCFEVADRTDEVSNIYTVRRR"
     gene            complement(2248..4263)
                     /gene="recG"
                     /locus_tag="VXE87_000716"
     CDS             complement(2248..4263)
                     /gene="recG"
                     /locus_tag="VXE87_000716"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0842299.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLQTIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKSIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFACKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(4282..5385)
                     /locus_tag="VXE87_000717"
     CDS             complement(4282..5385)
                     /locus_tag="VXE87_000717"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0842300.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(5375..5743)
                     /locus_tag="VXE87_000718"
     CDS             complement(5375..5743)
                     /locus_tag="VXE87_000718"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0842301.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5782..6813)
                     /locus_tag="VXE87_000719"
     CDS             complement(5782..6813)
                     /locus_tag="VXE87_000719"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0842302.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6815..7846)
                     /locus_tag="VXE87_000720"
     CDS             complement(6815..7846)
                     /locus_tag="VXE87_000720"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0842303.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7927..10440)
                     /gene="secA"
                     /locus_tag="VXE87_000721"
     CDS             complement(7927..10440)
                     /gene="secA"
                     /locus_tag="VXE87_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0842304.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDIITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10586..10873)
                     /locus_tag="VXE87_000722"
     CDS             complement(10586..10873)
                     /locus_tag="VXE87_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842305.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10901..11533)
                     /locus_tag="VXE87_000723"
     CDS             complement(10901..11533)
                     /locus_tag="VXE87_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0842306.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKFDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(11537..12178)
                     /locus_tag="VXE87_000724"
     CDS             complement(11537..12178)
                     /locus_tag="VXE87_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842307.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMILYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKV"
     gene            complement(12171..12962)
                     /locus_tag="VXE87_000725"
     CDS             complement(12171..12962)
                     /locus_tag="VXE87_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842308.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIVTYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLEKYEDNV"
     gene            complement(13147..13482)
                     /locus_tag="VXE87_000726"
     CDS             complement(13147..13482)
                     /locus_tag="VXE87_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842309.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYIPLY
                     ALFSLSWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13622..13957)
                     /locus_tag="VXE87_000727"
     CDS             complement(13622..13957)
                     /locus_tag="VXE87_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842310.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(14048..15358)
                     /gene="der"
                     /locus_tag="VXE87_000728"
     CDS             complement(14048..15358)
                     /gene="der"
                     /locus_tag="VXE87_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0842311.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(15372..16085)
                     /locus_tag="VXE87_000729"
     CDS             complement(15372..16085)
                     /locus_tag="VXE87_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0842312.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLKQKKLL"
     gene            complement(16082..16978)
                     /gene="dnaI"
                     /locus_tag="VXE87_000730"
     CDS             complement(16082..16978)
                     /gene="dnaI"
                     /locus_tag="VXE87_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0842313.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16979..18148)
                     /locus_tag="VXE87_000731"
     CDS             complement(16979..18148)
                     /locus_tag="VXE87_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0842314.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(18149..18622)
                     /gene="nrdR"
                     /locus_tag="VXE87_000732"
     CDS             complement(18149..18622)
                     /gene="nrdR"
                     /locus_tag="VXE87_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0842315.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18762..19127
                     /locus_tag="VXE87_000733"
     CDS             18762..19127
                     /locus_tag="VXE87_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0842316.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            19132..19827
                     /locus_tag="VXE87_000734"
     CDS             19132..19827
                     /locus_tag="VXE87_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842317.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19844..20611
                     /locus_tag="VXE87_000735"
     CDS             19844..20611
                     /locus_tag="VXE87_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842318.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20964..22163)
                     /locus_tag="VXE87_000736"
     CDS             complement(20964..22163)
                     /locus_tag="VXE87_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842319.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(22160..23053)
                     /locus_tag="VXE87_000737"
     CDS             complement(22160..23053)
                     /locus_tag="VXE87_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842320.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            23169..23249
                     /locus_tag="VXE87_000738"
                     /pseudo
     CDS             23169..23249
                     /locus_tag="VXE87_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            23734..23947
                     /locus_tag="VXE87_000739"
                     /pseudo
     CDS             23734..23947
                     /locus_tag="VXE87_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            24362..24979
                     /locus_tag="VXE87_000740"
     CDS             24362..24979
                     /locus_tag="VXE87_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0842321.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(25022..25909)
                     /locus_tag="VXE87_000741"
     CDS             complement(25022..25909)
                     /locus_tag="VXE87_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0842322.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(26058..27941)
                     /locus_tag="VXE87_000742"
     CDS             complement(26058..27941)
                     /locus_tag="VXE87_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0842323.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            28318..29772
                     /locus_tag="VXE87_000743"
     CDS             28318..29772
                     /locus_tag="VXE87_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0842324.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGNLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSHAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29753..30718
                     /locus_tag="VXE87_000744"
     CDS             29753..30718
                     /locus_tag="VXE87_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0842325.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30753..32027)
                     /locus_tag="VXE87_000745"
     CDS             complement(30753..32027)
                     /locus_tag="VXE87_000745"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0842326.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMAILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VVLSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(32027..33199)
                     /locus_tag="VXE87_000746"
     CDS             complement(32027..33199)
                     /locus_tag="VXE87_000746"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0842327.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(33330..33578)
                     /locus_tag="VXE87_000747"
     CDS             complement(33330..33578)
                     /locus_tag="VXE87_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842328.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(33646..34250)
                     /locus_tag="VXE87_000748"
                     /pseudo
     CDS             complement(33646..34250)
                     /locus_tag="VXE87_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(34312..34761)
                     /locus_tag="VXE87_000749"
     CDS             complement(34312..34761)
                     /locus_tag="VXE87_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0842329.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYNYIKTHRVS"
     gene            complement(34763..35521)
                     /locus_tag="VXE87_000750"
     CDS             complement(34763..35521)
                     /locus_tag="VXE87_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0842330.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(35636..37615)
                     /gene="pknB"
                     /locus_tag="VXE87_000751"
     CDS             complement(35636..37615)
                     /gene="pknB"
                     /locus_tag="VXE87_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0842331.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIILTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(37612..38352)
                     /locus_tag="VXE87_000752"
     CDS             complement(37612..38352)
                     /locus_tag="VXE87_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0842332.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(38367..39680)
                     /gene="rsmB"
                     /locus_tag="VXE87_000753"
     CDS             complement(38367..39680)
                     /gene="rsmB"
                     /locus_tag="VXE87_000753"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0842333.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(39673..40608)
                     /locus_tag="VXE87_000754"
     CDS             complement(39673..40608)
                     /locus_tag="VXE87_000754"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0842334.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(40621..43017)
                     /locus_tag="VXE87_000755"
     CDS             complement(40621..43017)
                     /locus_tag="VXE87_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0842335.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QESNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKVYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(43083..43397)
                     /locus_tag="VXE87_000756"
     CDS             complement(43083..43397)
                     /locus_tag="VXE87_000756"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0842336.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(43422..44048)
                     /gene="gmk"
                     /locus_tag="VXE87_000757"
     CDS             complement(43422..44048)
                     /gene="gmk"
                     /locus_tag="VXE87_000757"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0842337.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(44178..45791)
                     /locus_tag="VXE87_000758"
     CDS             complement(44178..45791)
                     /locus_tag="VXE87_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0842338.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSHEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(45982..46236)
                     /locus_tag="VXE87_000759"
     CDS             complement(45982..46236)
                     /locus_tag="VXE87_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV0842339.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(46240..46494)
                     /locus_tag="VXE87_000760"
     CDS             complement(46240..46494)
                     /locus_tag="VXE87_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV0842340.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(46732..47829)
                     /locus_tag="VXE87_000761"
     CDS             complement(46732..47829)
                     /locus_tag="VXE87_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0842341.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDSLAFGTEEVLD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETS"
BASE COUNT        13725 a        10919 c         9202 g        14238 t
ORIGIN      
        1 tttagtttca aaaaattctt ttatataata atgtccttga aagtagtttc agctgaacat
       61 ttatagtcca taaaaagaaa acagaaactc atctgttttt atactcaatg aaaatcaaag
      121 agcaaactaa gaagctagcc gcatgatgct caaaacactg ttttgaggtt gtagataaga
      181 ctgacaaagt cagctcaaaa caccgttttg aggtggcaga tagaactgac gaagtcagct
      241 caaaacaccg ttttgaggtg gcagatagaa ctgacgaagt cagctcaaaa cactgttttg
      301 aggtggcaga tagaactgac gaagtcagta acatatatac ggcaaggcga agctgacgtg
      361 gtttgaagag atttttgaaa agtattaaca cctacagaca agcctgacga tagcaagaac
      421 taccctactc gataggtatc ggcttttgct ttctgaaaaa aattatttta agcaatttga
      481 caaatctagc aacaaaaaat tctataaata caatagattg aaactagaat agtacacctt
      541 tgcttctaaa acattgttag aaatcgattt gactgtcctg atcgatttgt cctgttcttg
      601 tttcatttca ctatatttcc atgataaaac gcatagtatc aagttttctt aatcccctga
      661 tactatgcgt gtttgtaatt tttaagattt tgtgcttaga gtcgactcct tattttagat
      721 atttaaaagg aatctcactt ccacagagcc agttgtagac ttggtcatta acaaatacat
      781 tcatggcttc gtgagcatac tcaggcatga tacgataggt tttatcgcag gtcagacgat
      841 tataaatcgc aaactgggta atgggatagc aaacatcgtc gtccaagccc gtaatcatct
      901 taacctcacc ttggatacga tgggcaagat ttttgacatc gatataggca agggtcgcca
      961 tgatttcctc ctctgtttca tggaaggggt cgtgaaactt gaaataacgg aaaagttcgt
     1021 cgtaagcctc gctagtatta ccaatctcaa tcacccgtct gaagtctgac aagaagggat
     1081 aaatggcaac tgttttctga attcgaggat tgagcgctgc tgcaactaga gctagagccc
     1141 ctccttgtga ggcaccatag ctagaaagac gcttctcatc aacctgagac agactagcaa
     1201 caatttcgac caactggtaa atatccagat aaacatcctt ataaaagagg tggtcccgac
     1261 cttccatagc accacggata atatgcccct tcacggtatt tcctaaagga gaacgcaagc
     1321 cgtcttgtga gtaacctgac tggccccgca catccatgga aacaacaccg taaccagcta
     1381 cggtgaagcc cagcatgtcg gcccagtccc agccacgtcc catataacca tgaaaatgga
     1441 agattaatgg aaccttctcc tcactctttg gaagaacaat gcgtgcatag acctttcctt
     1501 ccttgcttcc ttcaaatgtt aactcatagc acttgacttg aggaatgtgg aaatctcttt
     1561 cctccaagtg gtaggatgga agcgtggaaa catttttcac ttccccatcc cagaaagcat
     1621 caaagtcttc cggaacctca tcccttcctc tataggtctt aatttcttct agcaaagctg
     1681 aatttttcat agcatgctcc ttttattttg taatcgttac cacaactgta gcatatctat
     1741 gtaatcaatg caagaaagaa gggtaaatag aaagtgaatt tagattcttt acttttagga
     1801 tgatgggctg aaagtagttt tagaaacgaa aaaagagcat ttcgctctct cttctgttta
     1861 tactagtttt ttgcttcctt cttttggaaa gtgatttggt aatttacttt aatcgttact
     1921 gtcatatgag agtcctcgtt tctttttgat gactttagta taagagccaa acctaaaaac
     1981 tagcttaata ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta ccgtatatat
     2041 gttactgact tcgtcagttc tatctgccac ctcaaaacag tgttttgagc tgacttcgtc
     2101 agttctatct gccacctcaa aacagtgttt tgagctgact tcgtcagttt catccacaac
     2161 ctcaaaacag tgttttgagc aacctgcggt tagcttccta gtttgctctt tgattttcat
     2221 tgagtataag ttttccttag agaaagctta atccagatgt tctttctttt ccagatgaag
     2281 ggcaatcatg cgccactctg gatcttcttg ccaagcttct atagaactaa tgtagctagc
     2341 aacctttctt gcttcttcta aaatcggaaa atcttcgata atatcagcca cttggaactc
     2401 tggaagtcct gactgtctgg ttccaaaaat ctcaccagaa ccacgcattt tcaaatcttc
     2461 ctccgcaagg acaaatccat tggtcgtttc tgtcatgatg cgcatgcggt ctttcccaga
     2521 atccgtcttg ggattggcaa cgagaacagc gtaggactgt ttgtcccccc gaccgacacg
     2581 acctctaagc tggtgaagtt gactgagacc gaagcgatcg gcatccatga taatcatgac
     2641 agtcgcattg ggaacgttga ccccaacctc aataaccgtc gtcgaaacca gaatatccgt
     2701 ctttctctcc ttgaaatcct gcatgatctg gtctttttcg tcactcttca tcctaccatg
     2761 tagaagagcc acctctgcct tgcatgcaaa atgagtcgtc aactcctctg ataaggcaat
     2821 ggcatttttc aaatctagag cttctgattc ttcaatcaaa ggagagatga cataggcttg
     2881 ggaacctttt tgaatttccc cctctaacca agtcaagacc tgaggtagtt gctcatgttt
     2941 gatccagcgc gtcacaatag acttccgacc tgctggcatc tggtctataa tggaaacatc
     3001 catatctcca aaggctgtga tggcaagcgt ccgtggaatg ggagtcgccg tcatcatgag
     3061 gacatctgga ttgtcacctt tttcccgtaa aatacgcctt tgccctacac caaaacggtg
     3121 ctgctcatcg ataataatca aaccaagacg agcatactcc accccatctt gtatcagagc
     3181 gtgagttcct ataatcaaat cagcctcacc cttggcaatg gtctgcaaga cttctctctt
     3241 ttctgcagct ttcaaggaac ctgtcaagag agccaatttc aaattgggaa aaaggttctg
     3301 taaactctca aagtgttgct ctgcgaggat ttctgttggt accattaggg cagcctgata
     3361 acctgctgtc actgccgcaa acatggccaa gccagcgact accgtttttc cactccccac
     3421 atccccttgt aggagacgat tcatgtggtg gtcggacttc atatcagtta aaatttcctg
     3481 caaactcttt tcctgagctt gggtcagggc aaaaggaaga cttactttaa ctgctgtcac
     3541 tttttcctga gaccaattca gaaccagacc acttccctga actctatttt cagacttgag
     3601 cgtctgcaac tgcatttgga aataaaagag ttcctcaaac ttgatacggc gaagagcctg
     3661 cttgtattct gccaaatcct ttggaaaatg catagctcgg actgcctgac aacgggacat
     3721 gagtttgtat ttgtctagta aagactgggg cagattttct tctatcaaga ggtccagtcc
     3781 ctgatcaaaa gccgtcttga tgaccttaac cagactggcc tgactgattc cctgagccag
     3841 acgatagaca ggctggaggt catcttctac ctgagccaga accttcatcc cagtcagact
     3901 agccttagcg cggtcccatt ttccaaagac agcaagggtt gctcccaact ctattttatc
     3961 agccagatag ggctggttaa agaaattcac cgcaaaaacg acctctccct gcttgagact
     4021 aaaacgcagg cgattgcgct tgaaaccata atactggaca ctagcaggag tcactacctg
     4081 accagaaaga actgccttct caccgtcttc cagctccagc acctgcttgg ttttgaagtc
     4141 ttcataacgg aaaggaaagt agagcaagag atcttgcaag ttttcaattc ctagtttggc
     4201 gtatttttct gctgactttg gtcccacacc aggcaagaca tgcaagggtt gatgtagatt
     4261 catgctccac tcctttcttt tctaataata ttctctcgga atacggtcgc tgaggaggca
     4321 aaccacctca tagttaatgg ttacgcggta ggtcgctacc tgagttgcag tgatttcctt
     4381 atccccattg gagccaatca aggttacctt ggttccgagt gggtaaggct taggcaatcg
     4441 aatagtgatt tggtccatcg aaaccctgcc gacaattggg caagcttggc catctaccaa
     4501 gacagagaaa ttttgcatgt ctcttgtcca tccatctgca tacccgattg gcacggtcgc
     4561 gatgacttgc tcgctatccg cttgataagt tgctccatag cccatgcaag ctccagctgg
     4621 aactgtcttg acatgaacca gagcagactc caaggtcaag gccggtatca aatcataagg
     4681 caaatccaag accgctccac ttggattgag gccatacatg gcatctccca tacgaaccgc
     4741 attgaaaata gtctctacat gccaaagagt cgttgcagaa ttgctagcat gaaccagctc
     4801 tggaacttcc ttcatactag ctaaaatagt tttaaaccgt tctaactggg cattaaaata
     4861 gtcatctgat tcctcatcag cagtagcaaa gtgggtaaag attccttcaa cacgaacacc
     4921 gtgttgttgg agcaaatctt gagcctgctc aacctcactg gcctctctaa aaccaatccg
     4981 tcccatccct gaatcaatct tgaggtggac tgtcaatcca gttaggtcca cttccttatc
     5041 taagagtgct tgaatccact ccagtccagc cactgtcaag gtgaagtcat attctttagc
     5101 tagagcaaca gcttcgattt cagaaactcc taaaatgagg attggcttgc tgagtccagc
     5161 ttgtctgagt tcaatggctt catcgatatt ggaaacgcaa aagccatcaa catcatcttg
     5221 aattgccttg gcaacggcaa cagctccatg accataagca ttggccttaa ccacagccaa
     5281 cttgagcgtt ccttgaggga tatgagcccc catttgctga atattttgtc gaatagctcc
     5341 cagatgaatc agagccttgg ttggtctatg tggactagct ttcatgattt tcctccaaaa
     5401 tgacactggc tgtcacaaac tgatcggtgt ggctgataga cagccaaatc tttcctgaaa
     5461 atggtgcctg actaaaataa ggcgccccac gttcattgtt caagacttcc aaatcctgaa
     5521 aaccgagctt gctaatgccc gttcccatag ccttggaaaa ggcctcctta gccgaccagc
     5581 gaccagctaa atattctatt tgcctgcgtc ctttgagact ggtgaagcgc tccatttcct
     5641 gagcggtcag tacacgctta gcaaatcctt catgtcgtgt aactgcgctt tctatcgaag
     5701 ccaattcttc gatgtcaatt ccgtgtccaa ctatcattct catcaaaagg agttgagatt
     5761 ccccaactcc atccttttca cttattttgt caaggtaaca taaatctctt ctaccaaggc
     5821 ctctgtattt tcccaaccta ggcaagggtc agtaatagag caaccaaaga tctctggttg
     5881 gttttgacga ccatctgcta ggtaagattc aatcataaat cctcgaaccg tctttttaat
     5941 tttctcattc caatcacgat tctgcaaggt ctggcgaaca attcgaatct gctccatata
     6001 ttgcttgcct gagttatcat ggttggtgtc aatgaggata aaaggatttt caagtcccat
     6061 ggtttcatag cgttcaatgg cttggagtag gttttcatag tagtaattcg gcatataatt
     6121 gccatactcg ttgactgctc cacggaggat aacatgggcc aaaggattac ctgatgtctc
     6181 aacttcctgc ccatgataaa ggaaggtttg cttgttttga gcagcataga tggcgttaaa
     6241 cataacaccc aaatttcctg aggttggatt tttcatccct actggtgcat caatcccaga
     6301 agccacaaag cggtgctctt ggtcttccac agaacgagct ccaacggcat ggtagctgac
     6361 caagtcatcc accaagatca gatttgacgg ataaagcatc tcatctgccg ttgtcaaacc
     6421 agtctctgta atcacgcggt agtgcaactg gcgcacagcc tgcaagccat taatcaggct
     6481 tggagcctta gaagtatctg gctggtgaac taatccttta tagccgtctc cattggtacg
     6541 aggcttagca gtatacacgc gcatgaccat gaaaatctta tccgctacct tcttttgcaa
     6601 ggcggataaa cggcgagcat attccaagac cgcctcttca ttatcagaag agcaaggacc
     6661 aatcaccaag agaatacggt catcttcccc tgaaataata tctgccaatt ccctgtcacg
     6721 gctttccttg agtctcaagg cttccgcaga caattgggtt tcagccttga tgacttccat
     6781 atcgatttct tgaccttttt caataaatgc catcttattc tcctaacgtt ttgtaaattt
     6841 ctctgacaag agcttctgtg ttatcccaac ccaggcaagg gtctgtgata gacttaccaa
     6901 atacttctgg ctcattttgt cgaccatctt ccagataaga ctcaatcata aaaccacgaa
     6961 cgaactgctt aattttttca ttccaagcac ggttaatcaa ggtctggcgg acaattcgga
     7021 tctgttcaat atactgctta ccagaattgt catgattggt atcaatgatg ataaaaggat
     7081 tttccaagcc cattttctca tactgggcaa tggtatcaat taaattgtca taatagtagt
     7141 tgggaatatt ttttccatac tcattaagag caccacgaag aatagcgtgt gaaagcgggt
     7201 tcccagttgt ttctacttct tttcctaaga aaaggaaact ttgtttgttt tgagcagcat
     7261 aaatcccatt aaacatgaca ttgagatttc cagaggttgg atttttaaaa ccagtagaaa
     7321 atcctgcccc acttgccaca aagcggtgtt gctggtcttc aactgaacgg gcaccaactg
     7381 ccatgtaaga aatcaaatca tctacaagcg gaaggttttc aggataaagc atttcatcag
     7441 cagttgtcat ccctgtttct gtgatgacac gatagtgaag atggcgaacg gctttgattc
     7501 cattgataag actaggcgct tctgtcgcgt taggctggtg aatcaagccc ttatagccat
     7561 ctccgttggt acggggtttg gcagtataaa cacgcataac cataaagata cgatctgcca
     7621 cttcttcttg taggactgcc aaacgcttag cgtattcaag gacagcttct tcgttgtcag
     7681 atgagcatgg cccgattacc aagagaattc gctggtcttc tccacgtata atggcttcta
     7741 gctcttgatc tcgctgtgat ttcctctcca aagcctgacc ttctaatttt gacaaggcac
     7801 gaacttcttc tatatttatt ttagagcttt ttgctgtaaa taccataact catctcctta
     7861 taaagcaaac ggatacccag taaaaattta cttttcacaa gatatccgcc tctaaactat
     7921 ctcattttat tgtcttttac cgtgacagtt tttaaatttc ttaccagaac cacatgggca
     7981 aagttcattg cgtccaatct ggctcaaatc caaatcttct ggcatacttg cttggtgagc
     8041 agcgatattg cgagtcgctg ttgtactgat atgacgttct gcctgtggtc tttcttgttc
     8101 atgaatttgt gctttcatca tcaagcgtgt cacatcaaac tcaatcgaac caatcatatc
     8161 attaaacata cggaaacctt ctgcctgata ctcaacaaca gggttgttct gagcatagcc
     8221 acgaagtcca accgcgttac gcaattgatc aagggcatcg atatgatctg tccacttgtt
     8281 atccaccact cgtagaatca aaactttttg gaattcttta actgcttctt catcgcgtag
     8341 ttttgaaacc tgactatcgt aaaccttcaa ggcacgttgg aaaagctctt ccttgatggc
     8401 cttatcagac aagcctgaca agtcttccat cgtaatagaa tcttcaggaa gcaagttgta
     8461 cttagcaaag ttcaaaattg cctctagttt ttcatcttgt ttggcacgcg catgaccatc
     8521 aacgacacgt tcaatcgtgc gcttaatcat agactgaatt tcaggtgcca agtcacgatc
     8581 tgcagtgatg atatcgtaac gttgagcata gataatctca cgttgttcac gcatgacatc
     8641 atcgtattga aggacttgtt tacgggtatc gtagttattt ccttcgacac gtttctgagc
     8701 tgcttcaacc tgacgcgtca acatgcgaga ctcaatcgcc tcttcagaca tgttcaagcg
     8761 ttcaaagatt cccttcaagc gttcagaacc aaaacgtttc atcaaatcat cttcaagaga
     8821 taggtagaat tgtgactcac ctggatctcc ttgacgacct gaacgtccac gaagctggtt
     8881 atcgatacga cgactttcat gacgttctgt accaataaca caaagtcctc caagttcacg
     8941 aacaccttca ccaagcttga tgtcggtacc acgacccgcc atgttggttg cgatggtaac
     9001 ggcaccacgt tgaccagcat tcatgatgat ttgggcttct ctatagtggt ttttggcatt
     9061 caagacttcg tgaggaacac cagctgcgac caatttctta gaaatgtagt cactagtttc
     9121 aaccgctact gtaccaacca agacaggttg acccttttgg taacgagcct taacgtcttc
     9181 gacaaccgct ttaaacttag attcgatact tgcataaaga aggtctgagt ggtcaatacg
     9241 ttgaacagga cggtttgttg ggattggaat aacacgaatg ttgtagattt cacgaaattc
     9301 ttcttcctca gtcttacctg tacccgtcat accagacaat tttttgtaca tacggaaaag
     9361 gttttggtac gtgattgagg cagatgtctt ggtttcatcc tggattggca caccttcttt
     9421 ggcttcaata gcttggtgca atccatcaga ataacgacga ccttccatgg tacgacctgt
     9481 aaattggtcg acaatcaaga tttcttgctc ttcgctcacc acatagtcaa tatcgagaag
     9541 catgatgtag ttggcacgaa gggcgttatc gataaagtgg gtcaaagcca cgttttcgat
     9601 gtcatagagg ttttcaagtt tgaagtagct ttcagccctg tcaatccctg aatcagacaa
     9661 accaatagtc ttagactgca catcgatgat gtagtcatct ttgttcaaag attttacata
     9721 gtggtctgcc atgtgataca actgactggt ttcaaccgca ttggcacctg atacaatcaa
     9781 aggtgtacga gcctcgtcaa tcaagataga gtcaacctca tcgaccaagg catagttaag
     9841 cggacgttgt accatgtttt cagcgcgaac gaccatgttg tcacgaaggt agtcaaatcc
     9901 gatttctgag ttagttgagt aagtaatatc acactcatag gcttcttttt tctccattgg
     9961 agatttggta gccaagttaa tccctactga caaaccaagc caagagtaca attcacccat
    10021 ctcagtcgcg tcacgttctg acaggtattc attaaccgta actacgtgaa cccctttacc
    10081 tgaaagggca ttgaggtata ccggcatggt cgcagtcaag gttttccctt cccctgtacg
    10141 catctctggc acgtcaccat ggtgaagaac aatccccccc atgacctgaa ccttataagg
    10201 gaagagacct aggacacgtt tggcaccttc acggacaacc gcaaatgctt cgtaaagcaa
    10261 tgaatccagt gattctccat tttgataacg ttccttaaat tcaactgttt ttgcttttag
    10321 ttggtcatca gtcaaagcag ccatttggtc ttcgtatttg aaaaccttgt cagccatctt
    10381 ttccagacga cggatttctc ctttatcatt ttcgataatt gtttttaaaa tattagccat
    10441 gtttttcctt actttaaatt ccgaatattt tagaatgttc ctttaatttt agcacaatta
    10501 ctgattattt tcaaggaaga atccccattt tgaaaaggaa aaagaggtta gttttcaagc
    10561 taacctctcc gacttttatg actgtttaat tgccaaaaat tggcaaaatg gcaaatgtga
    10621 taaataagtt aatccaaaga gaaagacagc aaatcagtcc aaaaacaaag agactgactt
    10681 tcttggacag caaggccatc aaaatggaca gaattccaaa aactagcaag actttctgta
    10741 tgatgaagat gtcaatcctt acccccagaa tcgctctatc ccaagggata aagaagaaag
    10801 acagccagat cagcagaact aaaccaatat aaaccttgga atagcgtgta ataaatgatt
    10861 ttagatgtgc cataagccat ctcctaggat tgtatatcct ttacatttgt atatgtccat
    10921 tttcgacaac taatacatct gtacaaaggt ctgaaatatc ttccgatatg tgcgacgtca
    10981 ggataaccag accattttct tttttcaggt aagataaaat gacctgtttg gttaacctca
    11041 cactcttctc atccaaagca ttcataggtt catcgagaaa gagtatagaa ggagaggaaa
    11101 taaaggcttg aatcaaggcc attttttgct ttgttcccaa ggataaatga cggtattcaa
    11161 cgtcttcaaa ttcctgtaaa tcatagtatt gaatccaata ggcaattctt ttttccgtaa
    11221 ctttagatga aaaatacctt aacagttcca aattttctct cagggataaa tgagataaaa
    11281 actcgacttt ttcaattaaa attcctgcat cctgaatata atgatttttt atcccgtaaa
    11341 ctttcccgtc ttgaagaact tttcctttgt caaacttaat ataaccagca agtatcttta
    11401 aaagaaccgt cttgccagat ccattatcac ctttaagtcc ataaattttt cctgattgaa
    11461 acaccaaatt caactgattt aaaataggtc ttttcccata aattttctgt ccatttataa
    11521 tttcaagtct catcgtttat actttcttaa atttctcttc caagcgacta acaatcaaca
    11581 taactaataa gcttaagagt agtaaataca ctgttacaat atgatccatc atccattctt
    11641 gtcccacaaa tgctaaaaaa tagagaaaaa aggaaaaacc agcgcccgca ctaatcagtg
    11701 ctatcagata agacagtagt aagtacaaaa tcattaactg agcaagtaaa aagaaaagtg
    11761 cgactgtttt gaaatgaatt cctagcggaa gtaaaccaag aaaccagaca aacaaatctt
    11821 gagtaaaaaa tttagaaatg acaaccaatc gtttccttgt ataatcgaaa aaggagcttg
    11881 attgatagcg aatcaagtga tggtaatggt ctgccaaatc actttcaagt aaaatgacag
    11941 agagccatcc taccatgaaa agcgaaaggt ttaacaagag tttggggatt tctaaattcg
    12001 cttcagaata gtcattatag gaaaaaattg aaatcaattc tctcttgaaa aagataacag
    12061 catcctgctt ttgaaccgct gttgacaata gatggtttat caaaatcatc atcagaacta
    12121 tacgaagtag taaaacaatc tttctcttta gccaaatatt gttaaaattc ttaaacatta
    12181 tcttcatatt tttcaagcac catataaggg acaacataaa ggatataagg agtaaagagt
    12241 ttcatcaaac ttacatcccc atagctagct tgcatcaaac tcgtcatagg aaccatatag
    12301 taaggcaagg cactatagag cagcatagaa ccaagccaaa gaaacatcaa ataggtgatt
    12361 gccgaacgag tcacattccc cacataatca actatttgta aaaaatagat tgcattgatg
    12421 aaaataccga ttagtaggac acaagtaaag aacaaatagc tttttatctc tccatctagg
    12481 agtctttgta aaccacttcc atcagaaaat agagaattcc atccaagagg agaaaaagtc
    12541 ccaaagaaat aggttacaat tgcaattatc agcacagtca ctaaatatat caaacaaggg
    12601 atacttgcaa cttgcaaagt caactttctt tttaaccctt gataactcac ttctcttcca
    12661 atactcaatc gtaaaacttt atttttcagc tcaatatatt gaaaacctag caaaacaatg
    12721 atgattggaa taataaatga ttgataaaaa cctagattga actggagaat acgaaaatct
    12781 aatgctgatt ttaataagtc atttttaatt gcttgtccat cgaatttagc tagatcgggc
    12841 gcatgaatat caaaaaagaa ataagtcatc aaaacatcac gataaaccaa agcaagaaaa
    12901 agcaaagtaa gcaagacata aacaaattta tgccttgcca aagttaagag aggaatcttc
    12961 ataagccacc tcctacaaat agaaagtaat ataatactca atgaaaatca aagagcaaac
    13021 taggaaacta gccgcaagtt gctcaaagca ctgctttgag gttgtagata agactgacga
    13081 agtcagttac atatataatc caaggcgacg ttgacgtggt ttgaagagat tttcgaagag
    13141 tataaatcaa tgccttccgc ctttagactt ccctagttcc cgtctcaagt caagcatttt
    13201 tttgaaacag atatagtcta accagtcact agcaaaagcg ataagtagta ataatagcca
    13261 aataccccat aacttgatat ctgtcaaatt tctcaagacg atattgaaaa acagaactga
    13321 aaaaactgtc caagaaaggc taaaaagagc atagaggggg atgtaaatcc agtaaaaata
    13381 gtaaaaaatt gggaaaaatt tactttctct attatccttg tcaatccagc tgaaaaagta
    13441 aaaacagggt aataagatta tcattttaaa caagtgttcc atcacaagcc tcctttttta
    13501 aattgttttc tttagtttcg ttctattaaa tgttattacc aatataaacc ttggaatagc
    13561 gtgtaataaa tgattttaga ggtaccataa gccacctcct acaaatagaa accgatataa
    13621 atcaatgcct tccaccctta gacttcccta gttcctgtct caagcgaaac atttctttga
    13681 aacaggaata agttaaccaa ttcataccaa tagctagcag aataaaaaga aaccaaatgc
    13741 cccataactt gatatctgtc acatttctca agacggtatt gaaaaacaga actgaaacaa
    13801 ctgtccaagc aaggctaaaa agagaataga aggggatgta aatccagtaa aaataataaa
    13861 aaattggaaa aaacttacta tttctgttgg ccttttcaat ccagttatca aaataaaagt
    13921 acggtgctaa aagtaagaat ttaaacaaat gttccatcac cgacatcccc ctccttcttt
    13981 tgatagcgtt ttctattatt ttattatatc aaaagaatct ggaaatgtca ttccagattc
    14041 tactttttta tttacgcttt cttgcgatga gatgaatcgg tgttccctca aagacaaagg
    14101 ccttgcggat ttgattttcc aagaaacgta ggtaagaaaa gtgcatgagt tcttcttcgt
    14161 tgacaaagat aacaaaggtt ggtggtttgg ttgccacttg ggtcgcatag aaaatcttga
    14221 gacgttttcc tttgtctgtc ggtgttgggt tgatggcaat ggcatccatg atgacatcgt
    14281 tcaagacagc tgatggaata cgtgtatttt gactttcgct gatttgctta atcatcccag
    14341 gaagtttgtg gagacgttgc ttggttaaag ctgatacaaa gataatcggt gcgtaaggca
    14401 ggtattggaa ctgctcacgg atatcttctt cccagttttt catagtgtgg ttatcttttt
    14461 caagcgtatc ccacttgttg accacgataa tcatcccttt accagcttca tgagcaaatc
    14521 cagcgatacg cttgtcgtat tcacgaatcc cctcttccgc attgatgacc attaagacca
    14581 catctgaacg gtcaatagca cgcatggcac gcatgacaga gtacttctca gtattttcat
    14641 aaaccttacc agacttacgc ataccagccg tatcaatcat ggtaaactct tgaccatctg
    14701 tatctgtaaa gtgggtatca atggcatcac gagttgttcc agcaacagga ctggcaatga
    14761 cacggtcttc tcccaagata gcattaatca agcttgattt tccaacgtta ggacgaccaa
    14821 tcaagctaaa cttaatgaca tctggatttt cttcttcata ttcatttgga aggttttcca
    14881 caatcgcatc tagtacatcc cctgtaccga ttccatggac agatgagata ggcagtggtt
    14941 cacccaaacc gagagcatag aaatcataga tatcatttct catctcaggg ttgtccacct
    15001 tgttgactgc gaggataact ggtttgtggg tcttataaag cttacgagct acgtattcgt
    15061 ctgcatcagt aattccttcc ttaccagaca cgacaaaaac gataacatct gcttcttcca
    15121 tggcaatttc tgcctggtgc ttgatttgtt ccatgaaagg agcatcgaca tcatcaattc
    15181 ctcctgtatc aatcatacta aaagagcgat tgagccactc acccgttgca tagatacggt
    15241 cacgtgtcac tccttcgaca tcttctacaa tggagattcg ctcaccagcg atccgattaa
    15301 atagggttga tttcccaaca ttgggacgtc ctacaatggc aatagttggt agggccataa
    15361 tttctcactt tctacaataa cttcttctgt ttaagatttt ttctagttga gcttggttct
    15421 gcttggccaa actgttctgc tagacgctga ctccagcttg tggtcgcacg cgctccagca
    15481 tagtcagcct gaacacggtc ataagcttgg attgcctcag ttgactgttc ttggtattct
    15541 tcctcaaaga caacattctc tagtggcagt ctcggtttca tatcatgatg ttgatttggc
    15601 acacccagtg ccatcccaaa gacagaatag gtgtagtcag gtaggttaaa gagctctgcc
    15661 acttcttcag acttgtatcg aaccaaaccg ataatcacac caccatagcc caagctttca
    15721 gctgccaaca aggcgttttg tccagcaaga gctgcatcga ccgaactaat caagagacct
    15781 tccacacctt ggggttggaa ggtgtcggta tgaagtcggg ctcccttttc tgctcggttc
    15841 aaatctccga caaagagaag gaaaacagca gactggcgaa tggcttcttg aggtaccaat
    15901 tcatacaagg catctttctt ctcttgactt cgtaccacaa tcacagagta ggattggaaa
    15961 ttcttccaag atgatgccat ctgggctgct gtcaaaatct catttaagtc tacttgggga
    16021 atttcttgct ctttaaacct gcgcactgaa gtatgagcct tcatcaattt aatggtttct
    16081 gtcatcgacg gtttactcct tctaaacgag tctcctcagc caaataacgg atgcgttcca
    16141 tgacacgtct ggcttcccag gtttcgtcat ttccattttt ccctttagcg aaatgcttct
    16201 ccaaatcttc aaagttgaag ttagaggtga aaaaggtcgg taaattttcc tgcatccgat
    16261 attggagaat gacctgcagg atttcatcac gcacccaagc ggtggattgc tcggcaccaa
    16321 tatcatctaa aatcaggact tcagaaagct taatctcatc cactaaggtc ttaacattgc
    16381 catcaccgat agcatttttg acatcaatga caaagctagg atagtggagg agagtggatg
    16441 atacaccacg tttttctgat aaatcatgag ctagggcagc caccatgaaa cttttaccca
    16501 caccaaagtc tccatataag taaagacctt tcaaattatt ggggtaatcg ttaacaaatt
    16561 ctatcattct ttttagaaca gttaagcgct gaacatcatc acgataaaca tctaaaaaac
    16621 tgacattttt caggctagat ggaaaattaa ttaagttgag acgtttcttg atagccgctt
    16681 ctttttcagc tgcgattagt tcaggagttt cttcataaga aacatccgca tagccatggt
    16741 tcatgactaa tataggcttg tagcctttgg caatataatc tgtatctcct cggaggaatt
    16801 tatctctctc agtgatgtat tggttaaact tggaaatact acggttcaac tcgtcctgat
    16861 tgagggattc ttgctggaca aaggccgcaa catcaggatc cttcatgatt ttctgaacta
    16921 aatcttgata gtgaaaacga cttggttgac gtttgagtac atctccgaca ctttccatct
    16981 aatcacctcc gttatctaat tttgctaata attctagggt ttggcgttcc atctcttcta
    17041 attcctcagc ggatgacgta tttttatatt caggattact ccatttagga atattggttt
    17101 ttgctggggc agtctgattc tgtttttgtg tttttgtttt ctgccctcgc tcacggatgc
    17161 gcaagactgc cttttctgcc gaatgaatct tttgataggc atagtcattg gctaccttca
    17221 tggcatattt ctcattgata tttgccgaat cgaccttatt aaaggtcaat aaaagaatga
    17281 tattgatgac ttcgtccagc aagcccaagc cagccatctg ttgcaagagt tctctttctg
    17341 tttgggtaat ggttcccttg cgtgtttgct tgatttctgc caagaactgc agggcagttt
    17401 tacttttggc ttctttgata atggttgttt ccttaagact aaagtcagag gaaactggtt
    17461 tttgagcaat tttttcacgc atgcgtttgg ttgaaataac ctgagaaaca gctgttgact
    17521 tggccaattg ataggtttca aaccaagtcc atttcttctc ctcggcaata gcaaagaggt
    17581 ttaagacatc ggactgctca tccgcaaaac gaagtccatc tcgagccatc agctggcgaa
    17641 aatgttccaa gtcaaaatca ttggccactt tcttcttgag accaaggtct tcttgactgc
    17701 ctagttctgc caattctgga aagacttgat tgagtgagac aggtatttct tcaccatcag
    17761 cactttcaac tttcaaatcc tccacagcag agtcgccaat ctttttctct aagagtctgc
    17821 gataaacagg atgctccaag aagtcttgac tagatagagg agcatggagg gctagctgat
    17881 aaacatcccc cttttgatag agggtcaaga gattaaaagc agataagatt ttcaatgatt
    17941 ttatcagtct atccatccca aagttgagat gattgaggat acttgaaaaa agatattcct
    18001 ttctaccatt atcccaaaaa ctgattgtat aaagataaag gctcagtgcc tcctgaccga
    18061 taatcgggag gtagcactgt accagagatg aggtatcttg cgacacccga ttattcttta
    18121 gataagaaaa acggtcaatt ggcttcattt atctttcctt tttcttttta gaggactggg
    18181 tgatttgttg gagcaagctc tctaactcac tgacatcctt aaaactacga tagacactag
    18241 caaaacgtac ataggtaatc tcgtccaatt cagccaactc ctccatgaca agtgaaccaa
    18301 tgtcctcact ttgaatttca ttttcatttc gaccacggag tttctgttcg atacgattga
    18361 ctaccatgtt gatttcatca cttgacacag gacgtttctg ggctgagcgg ataatcccat
    18421 taaagatttt atctctggag aattgttccc gtgtgccatc ttttttaaca accactaagg
    18481 ttctttcttc tactcgttcg taggttgtaa aacggtgttg gcactcgtcg cactctcgtc
    18541 ttctacgaat ggtgttccct tcttctgctt ggcgactatc gataacactt gacttggtag
    18601 ccccacattt tggacaacgc atcctttccc tccttatcgt tttcttttca ttataccatt
    18661 ttttaagcga ttcccaaaac aattcttctt tttgcttgac aagttttttg ttttgttgta
    18721 ttatttaatt aagacaaaag gataagagaa aggagactaa gatgtcctgg acatttgaca
    18781 acaaaaaacc catctattta cagattatgg agaaaatcaa gcttcagatt gtttcccata
    18841 cactggaacc caatcaacaa cttccaaccg tgagggagct agctagcgag gctggtgtca
    18901 atcccaatac catccaaaga gccttatcag accttgaacg agaaggattt gtctacagca
    18961 agcgaacaac tggacgattt gtgactaagg ataaggagct aatcgctcag tcacgcaaac
    19021 aattatcaga agaagaattg gaacacttcg tttcctccat gacccatttt ggctatgaaa
    19081 aagaagaact accaggcgta gtcagtgatt atattaaagg agtttaagcc tatgtcatta
    19141 ctagcatttg aaaatgtatc caaatcatat ggagcaacac cagcccttga aaatgtttct
    19201 cttgacattc cagctggaaa aattgtcggc cttcttgggc caaacggctc aggaaaaaca
    19261 accctgatta aactaattaa tggcctctta caaccagatc aaggacgtgt cctcatcaac
    19321 gacatggacc caagcccagc aaccaaggcc gttgtagctt atttgcctga tacgacctat
    19381 ctcaatgagc aaatgaaggt caaagaagcc ctaacctact tcaagacctt ctataaagat
    19441 ttcaatcttg aacgcgctca tcatctactt gcagacctgg gcattgatga aaatagtcgt
    19501 ctcaagaaac tatcaaaagg aaacaaagaa aaggttcaac tgattttggt tatgagccgt
    19561 gatgctcgtc tctatgtttt ggatgaaccc attggtgggg tggatccagc agcccgtgct
    19621 tatatcctca ataccattat caacaactac tcaccaactt ctaccgtttt gatttctacc
    19681 cacttgattt ctgatatcga gccaatcttg gatgaaattg tcttcctaaa agacggaaaa
    19741 gtcgtccgtc aaggaaatgt agatgatatt cgctacgagt caggtgaatc cattgaccaa
    19801 ctcttccgtc aggaatttaa ggcctaagca aaggagatta tttatgtttt ggaatttagt
    19861 tcactacgaa tttaaaaatg ttaacaagtg gtatttagcc ctctacgcag ccgtgctagt
    19921 cctttctgcc ctcatcggaa tacagacaca aggctttaaa aatctacctt accaagaaag
    19981 tcaggctact atgctacttt ttctagctac agtctttggt ggcttgatgc ttacacttgc
    20041 gatttcaacc attttcttga ttattaaacg cttcaaaggt agtgtctacg accgacaagg
    20101 ctatctgact ttgaccttgc cagtttctga acaccatatc atcacagcca aactaatcgg
    20161 tgcctttatc tggtcattga ttagcaccgc tgtattggct ctaagtgctg ttattattct
    20221 ggctttaaca gctccagaat ggattcctct ttcttatgtg attacatttg tagaaacaca
    20281 tctccctcag atctttctta caggtatatc cttcctacta aataccattt caggaatcct
    20341 ctgcatctac ctggctattt ccattggaca gcttttcaat gaataccgta cagcactcgc
    20401 tgttgcagcc tacattggta tccaaatcgt cattggattt attgaacttt tcttcaatct
    20461 tagttccaat ttctatgtca attcactggt aggactcaat gaccatttct atatgggagc
    20521 aggtatagcc attgttaaag aactcatatt catagctatc ttttatctcg gaacctacta
    20581 catcttgaga aataaggtta atttgcttta aataattttt acctagatat gtaacatact
    20641 catagaacaa aagagaccag gcaaaaagtc tttaaaatta gaaaacgcat agtatcaagt
    20701 gttaaaaatc cttgatatta tgcgtttttt gtgagctgac ttatttcctt tcgctatatc
    20761 gcaaaatgaa ataagaacgg aacgatggga ttttggaatt caaatcaatt tataagaatg
    20821 ttttagaagt aatattatcc tattccagat tcagttcact atacaattga gttttcaagc
    20881 aacctgttta cataatgtgt acataattag gttcgtgatt ccaccctttt cacctttaaa
    20941 aacctcgctt tcgcaaggct cttctattta taagataagg cacgtttaaa ggttttccaa
    21001 atccctaaat catccgtttg aagaacgaga ctagcataca tgcgtccgat aaatcctgtt
    21061 gctaccaccg caaaaatcac tgtaatagca agtgaaatcc atgcttccgc tccctccgca
    21121 tagccattaa tcgttcgaaa cggcataaag aaggtcgaaa taaagggaat ataagaacca
    21181 atcttcaaga ggagattgtc accagctgca cctagagctg tcactccaaa aaaaccaccc
    21241 ataatcaaaa tcatcaaagg cgacaaggct ttccctgagt cctcaggacg agaaaccata
    21301 gatcctagga aggctgccaa gactacgtac atgaaaagac tgatcaaaat aaagagcagg
    21361 gtattcagtg agatagcatc tcccaagtga tccaaaatac cagactgagc caagaatggc
    21421 aaatctttaa agagcaaaac ggcagccaga ccacctacaa catagatccc aatatgcgtt
    21481 aaaatcacta gaaacagagc catcatccgc gcatagaaat agtgacttgc ccttatgcta
    21541 gaaaagacga cttccataat tttggtgcct ttttcactgg caacttcctg agctgttaca
    21601 cccgcatagg taatcagaat catataaaga aagaatccta aggcacctgc tgcaattgtt
    21661 tgaataaact ttttattttc cttggcttca tcaatctttt ctgtgaattg aattgtctgc
    21721 gctaagcgtt tttcctgctc ttgagacaag gaagcagttg aacgattaag ctgattttgc
    21781 agttcattga gtgtacctgt aacctcaaat ttaattccat tttcaagcga tgtttcgcca
    21841 tgataaactg cctttagaac actatcttct tgatcaatgg tcaaataacc ttttaatttt
    21901 tcttctttaa ttgcttcttt ggcacttgct tcatctttat agtcgaagtt aacaccattt
    21961 acattcttca gtccttctgc tacagatggc actgttgtca ctactgccac tttattattt
    22021 ttagccatag aagaaccttg gagatgccca attcctacag agattcctaa aaagaggaac
    22081 ggcgaaatca ccataaagaa gaaactccat gactcgacat gtcgaagata ggtttccttg
    22141 attacaaccc acatatttct catacttcca ctcctgattc tagtttaaag atttcatcga
    22201 tagttggcgc ttgttggtca aatgttgcga tatattgacc ttgagtcaag attgggaaga
    22261 gttcccttcc agcgctctca tcctccaaaa tcaatttcca actgccttgt ttggtcaagc
    22321 tcacctgttt gacatgagga agattttcca attcttcctt gcttcgttca cttgaaacaa
    22381 agagacgcgt tttcccgtat tgattgcgga catcctgaac tggtccgtgc aagaccacac
    22441 ggccatctcg gatcatcaga atatcgtcac aaagttcctc aacattggtc atgacatggt
    22501 cagaaaagat aatggttgct ccgcgctctt tttcctgaaa aatgacttgt ttgagcaatt
    22561 ctgtattaac tgggtccaat ccactaaaag gctcatccaa gataatcagg tctggttcat
    22621 gaatcagagt aataatgagc tgaatcttct gctgatttcc ttttgacaga ctcttgattt
    22681 tatctgtcag ctttcctttc acttccaacc tcttcatcca ttgagggagt ttttctttga
    22741 cttctttggc atccatgcct tttagagtcg ccaagtagcg aacttgttca agaactgtca
    22801 atttaggcat gagactgcgt tcttcaggca gataaccaat ccgagcatag gtctcctgac
    22861 gaatatcctg accatccaga ccgatttctc cctgatattc taggaatttc aaaatactat
    22921 ggaaaatcgt tgtttttcca gcaccatttt ttccgactag tcccaaaata cgacctggtc
    22981 gcgcttgaaa gtcaatacca aacaaaactt gcttggagcc aaaacttttc tctagacttc
    23041 ttacttctag catctttcac ctccgaaatt tcttgcactc attatactcc tttttgatag
    23101 cctttacaat gtttttgtcc atttttagaa gactattgct gtgtaaaata tggcctggag
    23161 cacttttata ctcaatgaaa agcaaagagc aaactaggaa gctagccgta ggctgctcaa
    23221 agtacagctt tgaggttgca gataaaactg acgaagtcag ctcaaaacac tgttttgagg
    23281 ttgtggatag aactgacgaa gtcagtaact atatctacgg caaggcgaag ctgacgtggt
    23341 ttgaagagat tttcgaagag tattagtgat aaatccatta tacagtagca aacttaattt
    23401 ataccttccg ctcctcaact gtctattttt aatcctgaat tgttatttga gtaactcctt
    23461 tttcctcata aagttttctt cctctaaaac ttctggaaaa aagcgaatag tttcagacaa
    23521 catttttata agaaacaagt tcatctgtca tttcaagaag gagtaatcct ttatctacta
    23581 atggacggaa cggaattcaa ccgcttgtcc gatatgtttt ctaaggatta tatagcaaaa
    23641 tgaaataaaa acaggacaaa tagatcggga cagtcaaatc gatttctaac aatgttttag
    23701 aagtagatgc gtactattct agtttcaatc tattatatct attatgcaca ccactatagg
    23761 atctaataaa aatcacaaca agttcattca tagatggtta cctcagggaa ctaagaaaac
    23821 gactacaaag gaagtcgcat tcatcgaaaa gtggattaac aactatccta aaaaatgctt
    23881 gaactacaag tcccccagag aagacttctg gatgactaac ttgaacttga aatttagcaa
    23941 taattaattc accatctaac tatatttagt aattatttca gaactgatta atattaaaat
    24001 taactaacaa ttcaaaggat tcatactagc cataaattac gtccatcaga gagagactct
    24061 tactactttt agattttagt ctttctagct tcagaataca tctaaacttt agggaaaatg
    24121 actattcgaa agcgcgaatg cctcaaaatt atctcagata agctattcga aacttagaat
    24181 gcttttaaat tcatggaatt gcgattattc gaaacctaga atgcatataa cctttagttg
    24241 acagacctat tctaagtctc gaagggctat ttactttcta ttccttatca aaaaagactc
    24301 attccccctt tctcctccaa aatatggtat agtagaaata tactatctat gaggagttta
    24361 catgtcacag gataaacaaa tgaaagctgt ttctcccctt ctgcagcgag ttatcaatat
    24421 ctcatcgatt gtcggtgggg ttgggagttt gattttctgt atttgggctt atcaggctgg
    24481 gattttacaa tccaaggaaa ccctctctgc ctttatccag caggcaggca tctggggtcc
    24541 acctctcttt atctttttac agattttaca gactgtcgtc cctatcattc caggggcctt
    24601 gacctcggtg gctggggtct ttatctacgg gcacatcatc gggactatct acaactatat
    24661 cggcatcgtg attggctgtg ccattatctt ttatctagtg cgcctatacg gagctgcctt
    24721 tgtccagtct gtcgtcagca agcgcaccta cgacaagtac atcggctggc tagataaggg
    24781 caatcgtttt gaccgcttct ttatttttat gatgatttgg cccattagcc cagctgactt
    24841 tctctgtatg ctggctgccc tgaccaagat gagtttcaag cgctacatga ccatcatcat
    24901 tctgaccaaa ccctttaccc tcgtggttta tacctacggt ttgacctata ttattgactt
    24961 tttctggcaa atgctttgac acgtaaaaaa tccgtttggt ttcccaagtg gattttgtgc
    25021 tttattttga aacttctttt gcaagaacaa agttcccaag tgtggcagaa ccatttcctg
    25081 cgactgctgg cgtcacgata tagtcacgca catctggtac tggtaggtaa ccattaagaa
    25141 gagatgtaaa tttctcacgg acacggtcca gcatatgttg ttgagccatg acccctccac
    25201 caaagacaat cacgtctggg cggaaagtca ctgtcgcatt aaccgcagct tgagcgatat
    25261 agtaggcttg aacatcccaa acagggttgt tgagttcaat agtttcccca cgtacacctg
    25321 tacgagcttc caaacttgga ccagctgcat aaccttctag acatccctta tggaaaggac
    25381 aaacaccctt aaactctttt tcaatatcca ttgggtgtct agcaacataa taatgaccca
    25441 tttcagggtg acccacacca ccgataaact caccacgttg gatgacgcct gcaccgatac
    25501 ctgtaccgat tgtgtagtaa accaagtttt cgatacgacc accagcattg ttacgggcaa
    25561 ccatttcacc gtaagcagag ctgtttacgt ctgttgtgaa gtacattggc acgtttaggg
    25621 cgcgacgaag ggcaccaagc aagtctacat ttgcccagtt tggttttgga gtcgtcgtga
    25681 taaagccata agtttttgag tttttgtcaa tatcaatcgg cccaaatgaa ccaactgcaa
    25741 gaccagcaag gttatcgaat tttgagaaga actcaatggt tttatcgatt gtttcgattg
    25801 gagttgttgt tggaaattgt gttttttcta caacgttaaa gttttcatca ccgacagcac
    25861 agacaaactt tgtaccgccc gcttccaagc ttccatataa ttttgtcatg ataaacctct
    25921 tgtttttatt ttctttatta tagcatactt cgaaagtcta aatgtctcta ttttttagat
    25981 tttcctctgt aaatcttact atctaataaa aacgaacaaa catgtcattt gttcgttttc
    26041 acattagaga ggattgatta gattttcact tcgatcacag catccccctt cgaaactgaa
    26101 cctgttgcga ctggagctac tgaagcgtag tcagctgtat ttgtaacgat aaccattgtt
    26161 gtatcatcaa gtccagctgc agcgattttg tttgagtcaa atgttccaag aacatcgcca
    26221 gctttcacct tattaccttg agcaactttt gcttcaaaac cgtcaccgtt catagataca
    26281 gtgtcaatac caacgtgaat caaaacttca gcaccatttc ttgttttcaa accaaaagcg
    26341 tgccctgttg gaaaggcaat tgaaacttca gcatcagcta gtgcatagac cacgccttga
    26401 cttggtttca cagcgatacc ttgtcccata gctccacttg agaagactgg gtcattgaca
    26461 tcagcaagag cgacaacatc accgacgata ggagttacaa gtgtttcatt ttgaagagct
    26521 gctggcgcaa cttcttcttt ttcttcagcc acttcagctt gttttgcagc tgcagttgcg
    26581 tctacttcat cttcgtaacc aaacatgtaa gtaagagcaa aaccaagggc aaatgataca
    26641 gctaccataa gaaggtattg tggaagttgt ccgttaccaa cataaagcat tgtaccaggg
    26701 atgatggtga taccattacc agtaccagca agtccaagga tagaagccaa tccaccaccg
    26761 attgcaccag caatcaatga aaggaagaat ggtttacgga agcgcaagtt caccccgaag
    26821 atagcaggct ctgtaatacc taggaaggca gaaagagcag ccgggaaagc aagtgttttc
    26881 agttttggat tttttgtttt aacaccaacc gcaacagtag cagcaccttg agctgtcata
    26941 gcagctgtga tgatagcgtt gaatgggtta gcatggtcag cagcaagtaa ttgcacttca
    27001 agcaagttga agatgtggtg cacacctgac acgacgatca attggtgaac cccaccaatc
    27061 aagaaaccac caagaccaaa tggcatgcta agaatcgctt ttgtagcaat aaggatgtag
    27121 ttttcaacaa cgtggaaaac tggtccaata acaaagagtc caaggataga catgaccaaa
    27181 agtgtcacga atggtgttac caagaggtca atgacatctg gaacaacctt gcggacagct
    27241 ttttcaaatt tagctccgac aaccccgatg atgaaggctg gaagaacgga accttgcaaa
    27301 ccaacaacag ggatgaaacc aaagaagttc atcgctgtta cttcaccacc ttgagcaact
    27361 gcccaagcgt ttggaagtga gccagagaca agcatcatac caagaacgat accaacggca
    27421 ggatttccac caaatacacg gaaggttgac cacacaacca aacctggcaa gatgatgaag
    27481 gctgtatctg tcaagatttg tgtgtaagtt gcaaagtcac ctggaagtgg catttcaaga
    27541 gcgttgaaaa gaccacgcac acccatgaag agacctgtcg ctacgataac tgggatgatt
    27601 ggaacgaaaa catcaccgaa agtacggata gcacgttgga accagttccc ttgtttagca
    27661 acttctgctt tcatgtcatc cttagatgat gttggtaagc caagtacaac aacttcatcg
    27721 tacattttgt taactgtacc tgtaccaaag ataatttggt attgccctga gttaaagaaa
    27781 gcaccttgaa ctttttccaa gttctcaatc acttctttat tgattttctc ttcatctttg
    27841 accatgacac gtagacgagt cgcacagtgg gcaacactat tgacattttc acgtccgccc
    27901 aaggcatcga tgactttttt tgcaatttcc tgattgttca tttgcaaaaa tctccttata
    27961 taacattttg ttcttgtttg aaagcgattt tattcgccct tacgactatt attttatcat
    28021 gttttaaaaa tatgtcaagc gttttgcaga aaaaatattc tatccactta gtgggcaagt
    28081 tttagattga ttgtttttga ctgtttcatc aggaattcct tgaaaaataa gtttgaaacc
    28141 ttggttaaaa agtattttat ttcattatct ttcacatttt cgtaaaaatt tgattgattt
    28201 cctgtattta tttcatgata atcgtttgac agttttttct attttttaat ataaaaggct
    28261 tgcatttttt atcgaaaaca gttactatta aaagtgataa gatttttgga ggaatgaatg
    28321 gaatggacaa ctgagcgtcg ttacagactt tatcaagatt ggacgcaaga agaaattcaa
    28381 catataaagg aaaatatggc acaatctcca tggcatactc attaccatgt tgagccaaaa
    28441 acaggacttc tcaacgaccc aaatggcttt tcttactttg atggcaagtg gatcctcttt
    28501 taccagaatt ttccttttgg tgcagcccac ggtttaaaat cttgggcaca gctagaaagt
    28561 gatgatttgg ttcactttag agaaactgga gtcaaagttt tgccagatac tccattagat
    28621 agtcacggtg cctactctgg ttctgccatg caatttggcg ataacttatt cctattttat
    28681 acaggaaatg ttcgcgatga aaactggatc cgtcacccat accaaatcgg tgctttgatg
    28741 gacaaggagg gtaagattac aaagattgac aagatcttga ttgaccagcc agcagactct
    28801 actgaccact tccgcgatcc acaaattttt aactttcagg gtcaatatta tgccattgtc
    28861 ggcggacaag acttggagaa aaaaggtttc gttcgtctct acaaggctgt caataacgac
    28921 tacacaaact ggcaagcagt tggcaacctt gactttgcta acgaccgtac tgcctacatg
    28981 atggaatgtc ctaatctggt ctttgtagag gaacagcctg tccttctcta ctgtccacaa
    29041 ggattggata agaaagttct agactacgat aatatctttc caaatatgta taagattggg
    29101 gcttcctttg accctaaaaa tgccaaaatg gtagatgtgt ctcaacttca aaacatggat
    29161 tacggtttcg aagcctatgc aactcaagcc ttcaacgctc ctgatgggcg tgctctagca
    29221 gttagctggc ttggtttgcc agatgtttct tacccatctg accgttttga ccaccaagga
    29281 accttctctt tggtcaagga actcactatc aaagacgaca agctctacca gtatccagtc
    29341 gctgctatta aggaccttcg tgcttctgaa gaagccttct caaaccgttc ccaaaccaag
    29401 aacacttacg aacttgaact caacttggaa gccaatagcc agagcgagat tgtcttactt
    29461 gctgataaag aaggcaaggg actttcaatc aactttgacc ttgtaaacgg tcaagtgaca
    29521 gtggatcgta gccatgctgg agaacagtat gcccaagaat ttgggacaac tcgttcttgc
    29581 cctatcgaga atcaggctac tactgctaca atcttcatcg ataactctgt ctttgaaatt
    29641 ttcatcaata aaggagaaaa agtattttct ggtcgtgtct tcccacatgc ggaccaaaat
    29701 ggtatcctga tcaaatctgg aaacccaact ggaacttact atgaattaga ttatggtcgc
    29761 aaaactaact gatgtcgcca aacttgcagg cgtcagtcct actaccgttt ctcgggttat
    29821 caataaaaaa ggatatctat ctgagaaaac catccaaaaa gtcaatgaag ccatgagaga
    29881 attaggctat aaacccaaca acctggctcg tagtctgcaa ggaaaatcag ctaagttaat
    29941 cggcttgatt ttccccaata tttccaatgt tttctatgca gaattgattg ataaattgga
    30001 acaccaactc ttcaaaaatg gttacaagac catcatctgc aacagtgaac atgattctga
    30061 gaaggaacgt gaatacatcg aaatgttgga agccaatcag gtggacggca tcatttctgg
    30121 tagtcacaac ctaggaatcg aagactacaa tcgtgtgaca gcgccgatta tttcctttga
    30181 ccgaaaccta tcgccagaca tccctgtcgt ctcctctgac aactatgctg gtggggttct
    30241 tgctgcccaa accttggtca agacaggtgc ccagtctatc atcatgatta cagggaatga
    30301 caattctaat tcgccaaccg gactgcgcca cgctggtttt gcatccgtac tcccaaaagc
    30361 tcctattatc aatgtttcca gtgacttttc tcccgtcaga aaagaaatgg aaatcaagaa
    30421 tatcttgacc cgggaaaaac cagatgccat ttttgcttcg gatgatttga cagctattct
    30481 ggtcattaaa atcgctcaag aattgggcat ttctgtccca aaagagctca aggtcatcgg
    30541 ctatgatggg acctacttta tcgaaaatta ctaccctcaa ttggctacta tcaagcaacc
    30601 tttggaagag attgcttgtc tcactattga tcttctcttg caaaagattg aaggcaagga
    30661 agtcgccaca actggttact tcttaccagt tacgctatta ccaggaaaaa gtatttaaac
    30721 acaagaaaac tcagaccgat tcgtctgagt ttttatgatc ttaaattttc gagatagcgc
    30781 tgggctgtct ctaggttaaa ggttttatct gcgataagct gctcgactag gggagcaact
    30841 tcagattcac tagccccagc taggagagct agggatttgg cctgtagttt catgtggcct
    30901 tgctggatgc ccgtacttac caaggctttg agggctgcaa aattttgagc aagaccgatg
    30961 gacacgataa tctgggctaa ttctctggca gaaggatttc ctagtagatc atgactgaga
    31021 actacacgtg ggttgaggcc gatagagcca cccttagtcg ctacaggcat gggcagggtc
    31081 atctcaccga ccaattcttc tctttcaagg tccagcgtcc agcaactaag accttgataa
    31141 cgtccatctc gactggcaaa ggcatgggcc ccagcttcga tggcacgcca gtcattacca
    31201 gtggcaatca aaatcgcatc aataccatta aaaattcctt tattatgagt agcagctcgg
    31261 taaggatcag cctgcgcaaa ctgactagcc aacgcaattt tctccgcaat ctctcgtcct
    31321 tgatcctttt ggcggctcaa gtagcgaaag gcgatgcgac agcttgcagt caccagagaa
    31381 tcggtcgcgt agttggacag gattgccatg agactctgtc cctgactgag ttcttctaag
    31441 actggtttca aggcttccag catggtgttg agcatattgg cacccatggc ttcctgggta
    31501 tcgacatgaa tataaacaac gagaaagtct ggttcacctt ttatctgctc gacatgcaga
    31561 tcacgcgccc cacctccacg tttaacgata gaaggatagg cttgattggc aagctccaag
    31621 agctccgctt tcttgctggc aatcttctct tgcgctagtt taggattagc aacttgataa
    31681 agggctacct gcccaatcat ctgtcgctga tggacttgtg cagtaaaacc acctgcacgc
    31741 ttgatgattt tgctggcata gctggccgcc gcaaccacag agggttcttc tgtcacatag
    31801 ggaacggtgt attcctgacc gttgacaagt acctccggaa ccagtgaata aggcagagaa
    31861 aaagttccca ctacattctc actcagctgg tctgccacag tcacgctcat ctgttcatcc
    31921 ttctccagac tagcttgtct ctcaggacta aggagcgcct gagcttttaa cagctcgagg
    31981 cgctcttggt atgatttttt agaaaatcca ttccaactta tcttcattat ttttcaacct
    32041 tgctataacg gcgttggtgg tcgagaattt caaccaaggc aaaatcttga ttttcatagc
    32101 cagcaaactg ggcagagttt gtttcatcca agtttacttc ctcaaaaaag accttttcat
    32161 agtctgcaac ggatagggca gttcgttggt tgagcttgtt caagcggtct ttatccaaat
    32221 aagcttcata tccttcaacc aattcaccac tgaagaactc agccacagct ccacttccgt
    32281 aactataaag ggcgatttta tccccagctt tcaagctatc tgtattttcc aagagagaca
    32341 aaagtccaag gaaaagtgaa cctgtgtaga tattccccac cttttgactg tagagaatag
    32401 actggtcaaa atgcttttgt aagaggtctt ttttctcttg aggcaggctc ttatccatga
    32461 tttttttcaa gccttttagc gctaatttag gataaggcaa gtggaaacaa acagccgcaa
    32521 aatcatccaa agtaagctgg tagcgttttt gatattcaag ccaagtcgtt ttcaaactat
    32581 ccaagtattg ttgggtagaa tagacaccat ttacataagg agttgtcgag taatttggtc
    32641 gccagaaatc catgatgtca cgggtctgag ctacattgtc attattaaag gccatcatgc
    32701 gtggattttg tgtaatcaac atagctacac ttccagcacc ttgagttggt tctcctggag
    32761 tttcaatacc gtatttggca atatcactgg caatgaccaa gaccttggac tccggagaat
    32821 tttccacatg caatttggca taatggaggg cagcagtcgc tccgtagcag gcttctttaa
    32881 tctcgaaact acgagcaaag ggctggatgc ccagcaagcc atgcacaaag acggccgcag
    32941 ccttactctg gtcaattcct gactcggtcg ccacaatgac catgtcaact tcttgtcttt
    33001 cttgctcagt taaaatagag tcactagcac tggccgccaa ggtcacgata tcctcagtta
    33061 ggggcgcaat actcaattcc ttgagtaaga gtcctttact taatttttca gggtcaattc
    33121 ccctcgcttc tgctaagtct tgtaatttca agacatattg actggtcgca aaaccaatct
    33181 tatcaatacc gattgtcata tttacctctg ttttatcatt catgtaaaaa atcgttctat
    33241 actattttat cacaaatggc agtaaaagag agaaaaaaga cttgattcac caaatcaagc
    33301 ctcttattgg tcatcatttt aaagaatgat tagttgctag agagttcacc gatataagta
    33361 gctttataag ctccattcac agttatcagc tcctggagga tcaaatttcc tgagtaagtc
    33421 cttcccatct catctacaaa tttttgataa aactgactgg tcggaatttc tctgacatcc
    33481 ttatcaaatg tcttatcaag tgttttacta accttctcag caatcaattg atgctcttgc
    33541 catccacttt gaaactctga gcccgaacta gaaaccatga ctgggataaa caacaaggtc
    33601 agtagactta cagacaataa ggaaaatagt agacttcctg caaaactaga atcctagttc
    33661 atgattgata ataacagcaa tcaaattcat tcgtaatccg aagcgtttac gatgatttcg
    33721 ataggttgtt gaaaacattt taaacgtttt tactttggca aagatgttct caaccttgct
    33781 tctctcctta gatagcgcat ggttataagc tttatcttca gctattaacg gcttgaggtt
    33841 gctggattta cgtggagttt gtgcttgagg atatatcttc atgggccctt gataaccact
    33901 gtcagccaag attttaccag cttgtccgat atttctgcga ctcattttga acaacttcat
    33961 atcatggcaa tagaaacaat tctcccttga cttgtgacaa tcgcttgagc cttcatagcg
    34021 tggcattttt tttaccagaa tcattcgcta attctttttt tagggcgatt gatttgtact
    34081 tccgtcgcat caatcattac cgtgtcctca gaactgagag gagttcttga aatcgtaaca
    34141 ccactttgaa caagagttac ttcaacccat tggctccgac ggattaagtt gctttcgtgg
    34201 ataccaaaat cagccgcaat ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt
    34261 tgttaattta tttatctcat ttttcagaaa attcttttat ttctgtaaag tctacgatac
    34321 tcgatgtgtc tttatataat tatacagtct gagaatcact gttccgctag ccattccaat
    34381 agagattacc agagccaaca tgacaaccaa ggtcgcactt gccagtgctt tattatagtc
    34441 ccctgtcaca aaaaaggcag ttgttcggta ggagagataa cctggaacca gcggtgccaa
    34501 aatggccaag ataaagacca cagcaggtgt cttataaaga atacttaaaa tctggctgac
    34561 acaagaacca ataatggctg caatgaaggt agctacaatg acattggtcg gttccttgag
    34621 caagagatag attagccaga cagtcatgcc caaaatccct ccaggtaaga gcatagaccg
    34681 ttgcacattg agtacgatta aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa
    34741 taaaaaggtt gttagtgtca tattagttca tcaataccaa ggcgacagaa gttcctgccc
    34801 ctaaagcgag ggtaatgagc agggattcaa acatcttact cataccagag tttatgtggt
    34861 tggtcataat atcacggacc gcattggtca aggcaatacc tggtacaaac ggcatgaccg
    34921 caccagctat aatcaaatct gccgttgaag gaaaacctgt gtagcgagcc caaaactggg
    34981 caattatccc aaagacaaag gctccagcaa aggctgtcac aaagggaatt cggataaatt
    35041 tttccacata gagggaaaag gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt
    35101 cgtagatatt tccgctaaac ataactgaaa agaaaggagc actaaaggtc gcagccagag
    35161 ttacctgcaa cttagtatag ggaaggggtt gagcttgcaa ggccgtcaat tgcttaaagg
    35221 ctgtttctaa gtcaatctgc cccccaacta gctgacgaga aatctggttc acatcgcaga
    35281 ctttttcgat gttataagaa gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt
    35341 caatagagaa aaagatagcg gcaggcatgg caaggacatt gcaatccaca atcccctgcg
    35401 aatgcgcgat tcgaatcatg gtatcttcta cacgatggat ttctgagcca cttttaagga
    35461 gaatagtccc cgctagcata atcacatcaa tgacggcatt taattctttt gattcttcca
    35521 tgctttcctc cttttatcaa ctccctctat tctatcacaa atctggactc aaaaaaaatc
    35581 tttgccatga aatcatgaca aagattgatt actcattttg attatccatc tacttttaag
    35641 gagtagctga agttgtttta ggtttgtaga ttgaaatctt gactctagtc ttattgaggt
    35701 ctaccttttc acctgctcta ggactttgtt caacaaccat gccttctgca ctacctgcag
    35761 gcgctgtcgt cacttctaca acttctatat tagcttcctt aatcccaaca atttgaatca
    35821 aattgttctt agtaaactcc aagctggaac caatgtaact cggcatggca acacttgtaa
    35881 cttttttagc tactgtcaag acaatttgag taggtttact cacatcataa gtcgttccgg
    35941 cacctggact ttgtttcata atcgttcctg gttcgctttc gctggactct tcttcctcta
    36001 tcttaatcaa attctcagga accttcttct gcttgagttc tgagattact tctgtagagt
    36061 tccgtccaat atagttccct aattgaatcg tcgtagcttt tttagctact gtcaaaataa
    36121 tttgagttgc cttgctcaag tcataggtcg taccttctgg tagactttgc ttcaggaccg
    36181 ttccagcctc actctcattc gactcttctt cctcaatttt aatcaaatta tctggaactt
    36241 ttttctcttt taattccgcg ataacatcag aagatttccg gccgacataa ttactaattt
    36301 ggaaggattg tttgcctgat gagacaacca gattgatttt cgttccttct tttcgaccag
    36361 ttccagcgcc aggatctgta cggataatcc gcccttcttc caccttttca ctagcctctg
    36421 tcttctcctc accaatctca aaattggctt ttttgagcgt tgccttggcc tctgcaactg
    36481 tctgacctgc cacatctgga atggcaatgg ttgcaggagt tctggatagt atccaaataa
    36541 gagaagctgc caccaataca aggctggcca acaaaatcag gtaacgcatc ttaaatctat
    36601 gttttttcgg tgcttgtggt tggtaagttt cctctgtcac agcctggctt gggtttttga
    36661 ttgatttgtg ttctgtctgc gcttgaacct taggaataga tgtcaaggta ctctgagaaa
    36721 ccttcggcaa ggtcttggta tctgccttgc tcgtttcatc aaagattaac ttactttcat
    36781 ttctacgatt gtaggacaag ctactagaca agtccacata catctctgaa accgagcggt
    36841 agcgattggt caacttttta gcagttgcct tgataataac attttctaaa gcctgaggta
    36901 cagatggatt ttctgcaata acggacggca ggggtttctg gaaatgctgg agggcaatgg
    36961 tcaccgcgct atccccgtca taagggatat ggcctgtcaa catctcatag aaaataatcc
    37021 ccatggcata gatatcactc tgcacagtcg ccttagaacc acgcgcctgc tctggtgaca
    37081 agtaatgaac tgagcccaac atcgagttag tctgggtcag acttgtctct gcaaaggcta
    37141 cagcaatccc aaagtctgtg accttggcag tcccatctgg tgtcaaaagg atattttgag
    37201 gtttcaagtc cctgtgaaca attcctcgag tatgggccaa gcgcatagcc aagagaattt
    37261 gtcccatgat acggactgct tcttcattag aaagaggata atgttccttg atatagcgtt
    37321 tgaggtccag tccagccaca tactccatag ctaggtactg ttgaccgtct tcctcgccaa
    37381 tatctgttat ccgaacgata tgaggatggt ctagatctgc catagctctc gcttcacgct
    37441 gaaaacgagc tacagctatc gggtccgtct ggtagttggt cctcagaacc ttcactgcca
    37501 cttcttcccc atctaagatt aagtctttgg ctaggtagac atccgccatg cctcctcgac
    37561 caatctgttt gacaatccga tagcgtccgg caaaaatctt gccgatttgg atcattctgc
    37621 atcctcctcg ttcatagaaa caagggcaac cgtaatgttg tctaaacctc ctgcattgtt
    37681 agcaaaacga acaagtgtct ccgttttatc tgctaaagga atatcactgg ttacaatatc
    37741 acgaatctca ctgcctgaaa tcatgttggt caagccgtca ctattgagca agagatagtc
    37801 acctgactca aggataactg tcccaaaatc aggctgaatt tcatcttttt gcccaataga
    37861 ctgggtgata atattttttt gcggatgagc ttctgcctct tctggtgtca attgaccagc
    37921 cttgagcaat tcattaacca aggaatgatc gctcgtcaac tgatggtatt cttctccacg
    37981 aatcaagccg atacgcgaat caccaatatg agcatagata gcctgattat caataatagc
    38041 aaggacttcc aaagtagttc ccatgcctct gtaagcttca tcctgaccaa gctggtgaat
    38101 cttttgattt tcaatttcta ggtaatgggc gaaccattca cgcacttcat tgactgtatc
    38161 gatctgagta tcaacccaag ctacacccag gtctgtgact gccatttcac tagcgatatt
    38221 ccctgcgcga tgacctccca tcccatcagc taaaataatc atggtacgtc cagctctatt
    38281 gacatagtgg ttgacatagt cttggttatt tgttcgtttc tgaccaacat ctgttaataa
    38341 tgaaatttcc atgtgtcagt tccttcctaa tccgatatct tgcgaaattg actgatgaag
    38401 aatccatcac ttccatacaa ttcaggtgta atgaggatac agccgtcttt catgatatcc
    38461 ttacattcat gttctagttt tacctgctcg aactcgggat gactctctaa aaaggcctta
    38521 acgacttgaa aattctcctc tgagacgata gtgcaggtgc tataagttat tataccacct
    38581 ttgcctagta tttgacaaac actacctaat atttctaact gaatttcctg caaggacgcg
    38641 aaatctgccg tttctttatt gtatttgata tctggttttc ggcgcaaaag accgattcct
    38701 gaacaaggag catccaccaa aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc
    38761 tttctggcat ccaatttttg agtttgaacc cgatcttcaa ctcccagacg ttgggcattt
    38821 tcttgaatta aatccaactt atggtcgtac aagtccagag cagtaacctg acctgtcgta
    38881 agataagagg ctatatgggc tgttttccca cctggagccg cacaggcatc aagcactcgc
    38941 tcatcacctt gtaaatcaag cgtcggagca accagctgac tggactcatc ttggatggta
    39001 atggctccat tcgcaaacaa attatgccct gcaaaatgcc cctgctcctt aaccagacca
    39061 gtggttgcta aaagggaatt attcgcctcc aacaaggctt ggatttcctc ttttcgactt
    39121 aggtctgtta cacgaatact ggctttgttt cgcactaaca ggctttcaaa gatggctttt
    39181 gctctctcct ctccgtattc ttccttgagt ttggcaacta gccaaactgg gagagaatag
    39241 gcaatggagt cacgcttgtt ttttcgcttg atgctagcaa tatctggcca gccttcacgc
    39301 aagatacggc gaaggacagc gttgaccaat ttttcactgc cttttttacg gagtttggcc
    39361 aattccactg cttcattgac cacagcatga tctggaatct tgtccaaata gcggagttgg
    39421 taggcactca tgagaagaag gacatagagc cagctgtcta actggtctct gtcttcgata
    39481 aagtgggata ggtaccattc cagagtcagt ttacgggcta ccgttccata gactagctcg
    39541 gtcactaagc ccttgtctgc tgcagagagc tgactcccct tgaggtgttt atttaaggca
    39601 atatttgaat atgcttgatt cacaaaaaca tcctctagca ctgctagagc taaacttcta
    39661 gccgtttcta ctttagtcac caaatcgttc tcctacagtc aatgtacgtc caactccgtt
    39721 gaggaaggaa gcaatgtcca tcttaggctt accagctggc tgcacttgtt tgagggatag
    39781 agccccttca gccgttgcga caatcaattc tttcttgcag atagagagaa tctcacctgg
    39841 atttccctga ccttctactg gtagggcttc ataaatctta aagcggtcgc ccttaaggaa
    39901 agtatgggca acaggccagg ggttcattcc acgaatttgg ttaaagagtt gacgattggt
    39961 tttgttccag tccagttttt cttcctctgg ctttatattt ggagagaagg taacctgact
    40021 cgtatcctgc ggttcaggtt tgatatcacc agcaatatag gcaggcagag tgtccaaaag
    40081 caaatcacga ccaactagcg ccaatttttc aaacaaggtg ccaacattgt cctcatctgt
    40141 gatcggaatg ctgcgacgag aaatcatatc tcctgcatcc atttccttaa ccatttccat
    40201 gatggtcaca ccagcttcct catccccttg aatcaaggca taatggatag gcgcaccacc
    40261 acggtgtcta ggaaggaggg aggcatgaac gttgacagca aagtccatgc tatcaaggag
    40321 tttgcttggg agaaactgcc caaaagcagc agtcacaatt ccatctgctc ctagcttcat
    40381 aagttcttcc atctctggac ttccagataa tttttcaggt tggtagatag atagtcctgc
    40441 ttccttggca gcctgcttga ctggggtttc ttggataact tttttacgac caacagcacg
    40501 gtctggctgg gtcacaacgg ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa
    40561 gactgttgct gaaaagtcgg gggtccccat aaagattagt tttgtcatat cttctccttc
    40621 ttataaaaat tgctgcggct catggtcaat gctgagacgg agctcactat tttcccgttc
    40681 ttgagtcaag gctaaaacct ggttgagggt cggccccagc tcatcttcta aacggtattt
    40741 aattaaaatc tggtaatgat agaggttgtg ggtacgggca atcggttttg gcgttggccc
    40801 cagaatggga ctggtctctg acaagcctga ccgcaaaatg ttcatgactt cataggcacg
    40861 tttgaaaacc tcttcttctt tcttgtgaga aagggtaata ccaatcgtga aatagtaagg
    40921 tggatagccg agttgtcgtc tgattcccat ttcataggca taaaagcctt cgtaatcttg
    40981 atccttggca aatcgaatag catagtgctg cggattgtag gactgtatca agacttgacc
    41041 tgccttttca gcccgacctg ctcgacctgc cacctgagtc aagagctgga aggttctctc
    41101 agaagaacgg aaatcaggca gattcaaggc cgtatccgca tttagaactc cgactagggt
    41161 aacattggga aaatccaaac cctttgcaat catctgagta ccaagtaaaa tatccgcttc
    41221 ccctcgccca aactggtcaa gcaaggcttg gtgactgcct ttctttcgag tcgtatccac
    41281 atccatcctc agaatgcgag cttggggaaa gagttctgct agctcatcat aaaccttctg
    41341 agttcccgtc ccatagtaac gaatactgtg gctcttacag ttaggacaga cctgaggaat
    41401 atccttcgag aaaccacaat aatggcagtt catagtcttg gtatccatat gcaaggtcag
    41461 agaaatatcg cagttgggac aagtatccac cgtcccacac tcccgacaca tgacaaagct
    41521 agaataacca cggcgattga gcatgagaac cacctgctct tttttaacca gacggtcttg
    41581 gatagcctct agcaaaggag gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg
    41641 aaagtcaatc acttgaacct cagggattgt agccaaagga ttggcacgtt gggttagacg
    41701 taagtgttga tagacgcctt tgccagcacg cgcccggctc tctaagctcg gcgttgcaga
    41761 tccaagtacc agagttgctt gattatactg agcccgtaaa atagctacct ctctggcatg
    41821 gtaacgggga ttgctttcct gcttataagc cgcttcatgc tcttcatcaa taatcatgac
    41881 acccagattt ttcagaggag caaagatagc agatctggca ccaacaacaa cttgggcatc
    41941 gccacgctcc accttgcgcc attcatcata cttttcacca ttggataatc ctgagtgaag
    42001 aatggctacc ttgtccccaa agcgtgctat aaaacgctcg gtcatttgag gagtcaagga
    42061 aatctcaggt accagcaaaa tagctgtctt gcccttatcc agggcacctt ggataatctg
    42121 caagtaaacc tcggtcttcc cacttcctgt aatcccttga agtagaaagg gaggttgaga
    42181 actgccaata gaactcacaa ccgcatcacg cgcctgtctt tgttctggat ttaactccaa
    42241 aggtctactt gcttcaattc cttcaaaata agcagccgag cgttgaactt ccttttggac
    42301 tatggtaaca gcaccttgat ccacaaagaa gttgacttgc tctcgcgagt aggactccaa
    42361 caagctagcc aaggaagcgc tctctggatg agacagcaga taatctctca gttccaactt
    42421 tttcttggca cgtgtagaaa tctcaacacc ttctaattga gcatggtcaa cctcatacca
    42481 agactgggtc ttgaccttct tttgatcgac tgcctgatat tccagaccaa gcaggccttt
    42541 tctagtcaaa cgcatcattt cagcttgctt acctaaatcc agagaagaaa aggctagcga
    42601 atcttctgaa ccaaacaggc gtactcgttc ttcctgactc aagccttcca gaggatagag
    42661 aatcttgtca tagctagaat tcagaaatcc cggaagcatg gccttgagga tagagatttt
    42721 gtaggagaag acagatttgc gtaactcctc agccagccag agttgttctg gcgtgagaac
    42781 aggagaaaaa tccagcacct ctgcaatatc ttttaaatct tgctccatct cttctccatc
    42841 tgattgggac tccaaaccaa gaacaatccc ttgaatcagg cgattaccct taccaaaagg
    42901 cacatgaacc cgcatcccaa cttccagcat tccctcaaat tcctccggaa tcctgtaact
    42961 atagggctgg tccgtctgca tcaagggcac atctacgata atcttagcta gggccatctt
    43021 ctcacctcct ccttgtcagt acattcttgc aatagaaaaa ataagattga gtccccccaa
    43081 ccttaaattt tttcaccatc ttctttttct ttagcaattt gctctttgat tttcttttct
    43141 tcttcttctt tgcggcgttt ttcttcttcg atacggcgac gcactgcttc acgttttcct
    43201 tctggatctg ggtgaattgt aacgtttcct gattcgattt cttctaaagc gcgaagagtt
    43261 gatttttcag acttgaaacc ttgagttgct ggggcacctg cttccaattc gtgggcacgt
    43321 tttgcttcca agattacgag tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata
    43381 gagggtttta acatcatttg cttgtaccta ttttctaaat tttatcgggt agttggagat
    43441 tttggtaaca tctcctgata gtgaccaatg acacgatcca cacagaagtg ttctgcttca
    43501 atcacacatt tgacacgttc agcagctagg ggcacctgat cgttgacaat cgcataatca
    43561 tactcacgca tgagggcaat ttcttccttg gccttttcga ttcgttgggc aatcacttct
    43621 gcactatctg ttccacgacc taccaagcga tcttgcaatt catccaaatc tggtggtgtc
    43681 aggaagataa agacagcatc tggaaccttt ttcttgacct gaagagcacc ctgaacttca
    43741 atttcaagga aaacatcgat tcccttgtcc aaggtttcat tgacataggt cagaggagtt
    43801 ccatagtagt tgccgacata ttctgcgtat tccaacatct gtccttgacg aatcagctct
    43861 tcaaattctt cacgagtacg gaagaaatag tcaacaccgt ccacttctcc aggacgttgt
    43921 gcgcgtgtcg tcatcgatac agagtattga aattggtttt cagaactctc aaaaatctct
    43981 cttctaaccg ttccttttcc aacccctgaa ggaccagaaa aaacgattag taagcctcgg
    44041 tctgccattg tgtctccttt tagtcaatct gtgaaataac atttctctag aataatggca
    44101 aaaagccaga ttatccttta cagtctttct atctagtgta acaaaaaagc agtaattttt
    44161 caactgctct ttcttattta tttagcataa tctactgcac gaagctcgcg aatcacggtt
    44221 accttgatat ttcctggata atcgagattg ttttcaattt tcttacgaac tttgtgagcc
    44281 aagattgtga ctttgtcgtc cttgattttt cctggattga ccatgatacg aatttcacgt
    44341 cctgcttgaa gggcaaagct agtttgcact ccttcaaagc cgttagcaat ttcttccaaa
    44401 tcatggagac gcttgatgta gctttcaaga gactcactac gagcacctgg acgggctgcg
    44461 ctcaaggcat ctgctgcagc gacgataact gctatcacgc tctcagcttc aacatctccg
    44521 tggtgactag caatcgtatt caccacaact gggggttcct tgtacttacg ggccaattcc
    44581 ataccgattt caacgtggct accttcaacc tcatggtcaa tggctttccc gatatcgtga
    44641 aggaatccag cacgacgggc aagagccgca ttttcaccaa gttcgctcgc catgatacca
    44701 gccaacttag caacctcaat cgaatggcgc aaaacatttt gtccatatga agtacggaac
    44761 tgcaaacgtc ccataatctt catcaagtct ggatgaaggt ttggcgcacc aatttcatag
    44821 gcagcagcct caccgtattc acgaatctta ttgtcaatct cttgacggtt tttctcaacc
    44881 aactcttcga tacgagctgg atgtatacga ccatctttga gcaacatttc catagtcata
    44941 cgggcaatct cacgacgaat cggatcaaat cctgacaagg tcaccacttc tggtgtatcg
    45001 tcgataatca catcgacccc tgtcaaactt tcaaaggtac gaatgttacg accttcacga
    45061 ccaataatgc gtcccttcat agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc
    45121 gctacatatt caccagcgat acgttgcata gcttgaacca agatgtcctt ggccattttg
    45181 tcagaacgtt ccttgacctc ttgctcagct tcgcgaatgc gactggcaat ctccctggtc
    45241 aagttttcct ctgtctgagc caagataata tctcgtgctt ctgcctgaga cagagcacca
    45301 atacgctcta gttctgcttc tttttgtctt tcgacttcct ctaattgctc ttcacgcgca
    45361 tcaaggtttt tcgctctatc agaaatactt tgttcttttt gttcaagtgt ttgttcttta
    45421 ctcgtcaaat tgtcgtcctt acggtcaagg ctagtagctc tctctgtcaa acgactttcg
    45481 atttgtttga gttcttgacg ttctgattta aattcagcgt ccacttcttc acggtatttt
    45541 ctggcttctt ctttggcctc caatagtgct tcttttttaa gagacttgct ttcacgtttg
    45601 gcttcattaa caagtaaatc cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct
    45661 tgttcagcat ttaaaagcat caactctgca gcttcatgag atgatttcat cttagctgag
    45721 atgctgacat atccaatgac taaaccaatg atgacggcaa aaacagcaat cgcaagcgac
    45781 atgatctcca tgtttttacc tcattttatt gttattccga atgacataca ttcttttaca
    45841 ttctaccata aaaaagtgat tttcacaaac ctaaaataga atatgttttg gggaatttgg
    45901 aacacatttg ccaaaataaa cttgtttttt agaaatagta gtttagtaga gacttgagaa
    45961 aaagcctacc tttcaataga cttagtaatg atctttaaag gacaagaaag ccacgctatc
    46021 tccatccatc atataaatca agcgattttc tgcatcaata cgccgtgacc aggctccttg
    46081 gtaatcatat ttgagtggct ctggttttcc tattcctgta aatggatcgc gttgaatatc
    46141 cttgattaat ttattgattc tttttagtgt ttttttatct tggttttgcc agtagcaata
    46201 atctgcccac gcatcttctg taaacttgag tagcattcat cactcctcaa tcacatggac
    46261 ctgagtgctt ccagcacgga cttgagccat tcctcgcaaa accttgtctg ataactcctt
    46321 attttgggcg attctcaggg tttcctgaat actgtcccat tcgctctttg aaagaactac
    46381 aatgtcctca tctggatttt tattgaccac cgtcaaaggc tcaaattcat catttacctt
    46441 cttcatgtag tcctttaaat gatttcggaa tgttgagtaa aggactgctt ccataaccat
    46501 acctcgtttt agctcttttc cactattata cacgaaaaga aagaaattgt caggaacttg
    46561 tacaagattt tcttttctat ctatttatac tcaatgaaaa tcaaagagca aactaggaaa
    46621 ctagccgcag gctgtacttg agtacggcaa ggcgacgttg acgcgatttg aatttgattt
    46681 tcgaagagta ttattcgtaa aaaatctcaa aaagcctacc tttcggtaga cttagcttgt
    46741 ttctattcta atcggcactc ttccaaaatt ttgctctgct atacttggct ttcctagttg
    46801 gtaaatctgg tctgcttttt gggtcatagc atcccaaggt tctttgccaa ttcggctgac
    46861 tagattgacc tgtcctttca gagacttgag atgttgcctg cctttttcag taaatccaag
    46921 gacatgaatg gcttctggca agacattttc tctagcctgc accaaaatat aggtcaatag
    46981 gcgtctgaca cgcgccttgg tgtaacgttt ggtcgcaacc gcctcgacca actcttctac
    47041 agactgggct gttttaatag cttctttaat gcgcacagcc atttcttgat tgacctgata
    47101 gatggtggtt aggtcgggat ttgacaagat ttgatagcgg agcaagggaa aatagtcttc
    47161 ccagatcacc ttactggcct gctcaaatag ggcaacagaa ggcataaagc gttctaagaa
    47221 atcttggtcc ttctgatgtt gacggagggc tgtcgccgag gcaaagtcca catctttatt
    47281 cacagaatgg taacctgccc cctgacgctg aataggatgc agcttgatat ttcgtcctgc
    47341 aactgccttg gcataggcca gagcaagaac atgattgggg gtattacctg aaaaatcaag
    47401 accagcaaat tccttccaca tagcttgggt tttctgggga taggaaaggg aatcaggcag
    47461 attttccaca aatttctcca tctcagcacc tttctctgtg tataagtcag cgattttttg
    47521 ataatctaga acttcttctg tcccaaaagc gaggctatct atgcccaacc gagctaagat
    47581 atccacggcc ccttgaccga aaaaatctgc cgcctgaacg ctgactaaaa agggcaattc
    47641 cactaccaga tccgctccat tttccagcgc catctgggct cgtgtccact tatccacgat
    47701 agcaggttct ccacgctgca tgaaattccc tgacatagcc acgattttca gcccctccgc
    47761 ttgatccagc aggtatttgt gtccattatg aaaaggattg aactccgcga taatacccgt
    47821 gatggtcata gtaatctcct acttctttag tatcaaattg agtcaattat attctgtagg
    47881 ctccgttttt gagtagttgt ttcctcaatg aatttaattg accattcttt taagtaattg
    47941 tgtctactaa aataccagcc atttatccac ttatttatta aagttttttc atcatcgttc
    48001 aacatgttat aatattttct ttcatttatc ttccaatttg atactatatc agactctaat
    48061 ttttctatat tttcataatc actt
//
LOCUS       DAVLIK010000013        44632 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLIK010000013 DAVLIK010000000
VERSION     DAVLIK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.013"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            24..1292
                     /locus_tag="VXE87_000762"
     CDS             24..1292
                     /locus_tag="VXE87_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0842342.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLEDCE"
     gene            1289..2185
                     /locus_tag="VXE87_000763"
     CDS             1289..2185
                     /locus_tag="VXE87_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0842343.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            2200..2517
                     /locus_tag="VXE87_000764"
     CDS             2200..2517
                     /locus_tag="VXE87_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0842344.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            2534..2851
                     /locus_tag="VXE87_000765"
     CDS             2534..2851
                     /locus_tag="VXE87_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0842345.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            2861..4216
                     /locus_tag="VXE87_000766"
     CDS             2861..4216
                     /locus_tag="VXE87_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0842346.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            4539..6014
                     /locus_tag="VXE87_000767"
     CDS             4539..6014
                     /locus_tag="VXE87_000767"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV0842347.1"
                     /translation="MVQTKQPNIILIVVDQMRADVLSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            6011..6859
                     /locus_tag="VXE87_000768"
     CDS             6011..6859
                     /locus_tag="VXE87_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV0842348.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGTPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            6874..7644
                     /locus_tag="VXE87_000769"
     CDS             6874..7644
                     /locus_tag="VXE87_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0842349.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(7922..8209)
                     /locus_tag="VXE87_000770"
     CDS             complement(7922..8209)
                     /locus_tag="VXE87_000770"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0842350.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            8518..8790
                     /locus_tag="VXE87_000771"
                     /pseudo
     CDS             8518..8790
                     /locus_tag="VXE87_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8901..9104)
                     /locus_tag="VXE87_000772"
     CDS             complement(8901..9104)
                     /locus_tag="VXE87_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0842351.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(9135..9743)
                     /locus_tag="VXE87_000773"
     CDS             complement(9135..9743)
                     /locus_tag="VXE87_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0842352.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(9782..9952)
                     /locus_tag="VXE87_000774"
     CDS             complement(9782..9952)
                     /locus_tag="VXE87_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0842353.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(9964..10530)
                     /gene="amaP"
                     /locus_tag="VXE87_000775"
     CDS             complement(9964..10530)
                     /gene="amaP"
                     /locus_tag="VXE87_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0842354.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(10614..10778)
                     /locus_tag="VXE87_000776"
     CDS             complement(10614..10778)
                     /locus_tag="VXE87_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0842355.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            11181..12662
                     /locus_tag="VXE87_000777"
     CDS             11181..12662
                     /locus_tag="VXE87_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0842356.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            13024..14025
                     /locus_tag="VXE87_000778"
     CDS             13024..14025
                     /locus_tag="VXE87_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0842357.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            14175..15092
                     /locus_tag="VXE87_000779"
     CDS             14175..15092
                     /locus_tag="VXE87_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0842358.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            15103..15993
                     /locus_tag="VXE87_000780"
     CDS             15103..15993
                     /locus_tag="VXE87_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0842359.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            16022..17638
                     /locus_tag="VXE87_000781"
     CDS             16022..17638
                     /locus_tag="VXE87_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0842360.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            17648..18967
                     /locus_tag="VXE87_000782"
     CDS             17648..18967
                     /locus_tag="VXE87_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0842361.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVATKHKDNVGCIVLLGSDNLVEWQFESIFLKGREHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(19175..19247)
                     /locus_tag="VXE87_000783"
     tRNA            complement(19175..19247)
                     /locus_tag="VXE87_000783"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19212..19214),aa:Lys,seq:ctt)
     gene            complement(19511..20782)
                     /locus_tag="VXE87_000784"
     CDS             complement(19511..20782)
                     /locus_tag="VXE87_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0842362.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            21052..21291
                     /locus_tag="VXE87_000785"
     CDS             21052..21291
                     /locus_tag="VXE87_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842363.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVYSNNGLKKYEK"
     gene            21456..21635
                     /locus_tag="VXE87_000786"
     CDS             21456..21635
                     /locus_tag="VXE87_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842364.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            21778..21951
                     /locus_tag="VXE87_000787"
     CDS             21778..21951
                     /locus_tag="VXE87_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0842365.1"
                     /translation="MTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGELN
                     KYTERGIGKQAGL"
     gene            21988..22440
                     /locus_tag="VXE87_000788"
     CDS             21988..22440
                     /locus_tag="VXE87_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0842366.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKYFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            22731..23201
                     /locus_tag="VXE87_000789"
     CDS             22731..23201
                     /locus_tag="VXE87_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0842367.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            23220..24308
                     /locus_tag="VXE87_000790"
     CDS             23220..24308
                     /locus_tag="VXE87_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0842368.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLVPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            24289..24717
                     /locus_tag="VXE87_000791"
     CDS             24289..24717
                     /locus_tag="VXE87_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0842369.1"
                     /translation="MELEISDFLGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKIYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            24855..25805
                     /locus_tag="VXE87_000792"
     CDS             24855..25805
                     /locus_tag="VXE87_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0842370.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            25807..26550
                     /locus_tag="VXE87_000793"
     CDS             25807..26550
                     /locus_tag="VXE87_000793"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0842371.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            26561..28357
                     /gene="pepF"
                     /locus_tag="VXE87_000794"
     CDS             26561..28357
                     /gene="pepF"
                     /locus_tag="VXE87_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0842372.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGVDVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQINLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEATIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(28417..29094)
                     /locus_tag="VXE87_000795"
     CDS             complement(28417..29094)
                     /locus_tag="VXE87_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842373.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            29341..30111
                     /locus_tag="VXE87_000796"
     CDS             29341..30111
                     /locus_tag="VXE87_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842374.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            30104..30868
                     /locus_tag="VXE87_000797"
     CDS             30104..30868
                     /locus_tag="VXE87_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842375.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            31292..32083
                     /locus_tag="VXE87_000798"
                     /pseudo
     CDS             31292..32083
                     /locus_tag="VXE87_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
     gene            32194..32862
                     /locus_tag="VXE87_000799"
     CDS             32194..32862
                     /locus_tag="VXE87_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0842376.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEK"
     gene            complement(32887..33156)
                     /locus_tag="VXE87_000800"
     CDS             complement(32887..33156)
                     /locus_tag="VXE87_000800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842377.1"
                     /translation="MLKAVFEVIDKTDEVSSKHCFEVADRTDEVSLKHCFEVVDRTDE
                     VSLKHCFEVADRTDVVSNHTYGKVKLTWFEEIFEEYHTKKPCSSR"
     gene            complement(33206..33739)
                     /gene="queF"
                     /locus_tag="VXE87_000801"
     CDS             complement(33206..33739)
                     /gene="queF"
                     /locus_tag="VXE87_000801"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0842378.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(34044..34358)
                     /gene="trxA"
                     /locus_tag="VXE87_000802"
     CDS             complement(34044..34358)
                     /gene="trxA"
                     /locus_tag="VXE87_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0842379.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(34375..34596)
                     /locus_tag="VXE87_000803"
     CDS             complement(34375..34596)
                     /locus_tag="VXE87_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0842380.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(34696..35076)
                     /locus_tag="VXE87_000804"
     CDS             complement(34696..35076)
                     /locus_tag="VXE87_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0842381.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(35219..36172)
                     /locus_tag="VXE87_000805"
     CDS             complement(35219..36172)
                     /locus_tag="VXE87_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0842382.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(36240..37447)
                     /gene="sstT"
                     /locus_tag="VXE87_000806"
                     /pseudo
     CDS             complement(36240..37447)
                     /gene="sstT"
                     /locus_tag="VXE87_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            37586..38146
                     /locus_tag="VXE87_000807"
     CDS             37586..38146
                     /locus_tag="VXE87_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV0842383.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            38203..39111
                     /locus_tag="VXE87_000808"
     CDS             38203..39111
                     /locus_tag="VXE87_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0842384.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            39063..39653
                     /locus_tag="VXE87_000809"
     CDS             39063..39653
                     /locus_tag="VXE87_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0842385.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            39656..40762
                     /gene="yqeH"
                     /locus_tag="VXE87_000810"
     CDS             39656..40762
                     /gene="yqeH"
                     /locus_tag="VXE87_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0842386.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            40976..41287
                     /gene="yhbY"
                     /locus_tag="VXE87_000811"
     CDS             40976..41287
                     /gene="yhbY"
                     /locus_tag="VXE87_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0842387.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            41339..41968
                     /locus_tag="VXE87_000812"
     CDS             41339..41968
                     /locus_tag="VXE87_000812"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0842388.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            41968..42561
                     /gene="yqeK"
                     /locus_tag="VXE87_000813"
     CDS             41968..42561
                     /gene="yqeK"
                     /locus_tag="VXE87_000813"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0842389.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            42562..43062
                     /locus_tag="VXE87_000814"
     CDS             42562..43062
                     /locus_tag="VXE87_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0842390.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            43075..43428
                     /gene="rsfS"
                     /locus_tag="VXE87_000815"
     CDS             43075..43428
                     /gene="rsfS"
                     /locus_tag="VXE87_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0842391.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            43748..44488
                     /locus_tag="VXE87_000816"
     CDS             43748..44488
                     /locus_tag="VXE87_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0842392.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDETPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
BASE COUNT        13470 a         7732 c         9566 g        13864 t
ORIGIN      
        1 aatatattta agaggaaaag gttatggaaa aattattaca agaaaagtta cttccagtag
       61 cggctagatt gggtaataat aaagcgttgg tttctattcg agacggtatt actctaacta
      121 tacctttatt gttgataggt tcattactaa tggttattgc aagttttcct attccaggat
      181 gggaaaaata tctgggtgat attggtgttg ctgactattt atggaagggt gttgatagta
      241 gttttggatt acttggtctt gtagctagtt ttggtatcgc ttactttatg gctagacaat
      301 acaaagttga tggtattcct gctggtattg tgtcattatc atcttttatt acagttacgc
      361 ctttcattag aggagaggct ggagcaggaa tgcctaccgc tttcatggca tcaaaaggtt
      421 tatttgttgc tatgatttta ggattgatta atggctatat ctaccaatgg tttataaatc
      481 ataatataca gataaaaatg ccggatggtg ttccaccagc agtatctaaa agctttagtg
      541 ccattattcc tggtgcagtg actattgttg gttggttgat tgtttatgca actttagata
      601 aattaagttt acctaatctt catgaaattg ctcaagtagc tttgggaggt ccacttggac
      661 ttttaggaaa taatgttatt ggccttctta tcttaatttt ccttaatagt agtttttggt
      721 ttgtaggatt acacggagga aatgttgtta atgcagttat gaaaccgtta tggttagcta
      781 atctagatgc aaataaagta gcttatcaaa ctggagaaac tcttccaaat atttttacta
      841 gcgtatttat ggataatttt gtattcatag gtggcggtgg tgcaaccata ggtttagttc
      901 ttgcgttagg atatttagca cataagaaga aagctagtaa acaactaaaa actttggcac
      961 ctataactgt tatacctgga ttatttaata taaatgaacc agcaatgttt ggcgttccta
     1021 ttgttttgaa cattttgtta ctagttccat ttatcttagc tccaatgttt aacttactag
     1081 tagcgtgggg agcaatggca tcaggtttgg ttccgctaac ttatacagat ccaggttgga
     1141 ctatgccacc tgttataagt ggtttacttg ctacaggaag tatttctggt tcattattac
     1201 aaattgtatt gattgttttg gatgtcttac tttatttacc atttgtaata gctattgaaa
     1261 aacggtttaa gttattggag gattgcgaat gaaacgttta attagtgcaa atccatctga
     1321 gatattacag atgaatgctg aagaattaaa acaaagtatt ttagcaagtg aaggtagagt
     1381 tgttctatct gaaaatgtag ttactcgtga gacatttgtt ggggatataa ctaattctga
     1441 aattgctaga gcttttggag ctgatatgat tttattgaat tgtgttgatg tttttgagcc
     1501 taaaatttat gctttggata gttcaggtga tgatgttatt catcgcttac accagcttgt
     1561 tgcttgtcca attggtgtaa atttggaacc gattgaccca tctgcaaaga tgctagagga
     1621 aacacaggaa attgttgcag gtcgtgttgc tagtgttgaa acattgaagc gaatagagga
     1681 gttaggtttt gactttgtct gtttgactgg aaatcctgga acaggagtta gcaatcgaga
     1741 aatcattaag gctgttcaaa ctgctaagga aaacttttct ggtttgatta ttgcaggtaa
     1801 gatgcacggg gcaggagtga atgagcctgt ggcagagctt tctgtcgcag agcaattgtt
     1861 ggaagcaggt gcggatgtga tacttgttcc agcagttgga accgttccag cctttcatga
     1921 ccaagagttg cgtgaagtcg ttgatctcgt tcatagtaag ggtggtcttg tattgagtgc
     1981 tattggtact agccaagaaa catctgatac agatactatt aaggaaattg cacttagaaa
     2041 taaaatttgt ggagttgata ttcaacatat aggtgacgca ggatatgggg gactggcaac
     2101 agtcgataat atttatgcat tgagcaaggc aattagagga gtgagacata cagtatctcg
     2161 cttggctagg tcagtaaata ggtgataaag gagtaagcta tggctaaagt aacaattatg
     2221 ttagcatgtg cagcaggtat gagtacaagt ctgctagtga caaagatgca aaaggcagca
     2281 gaagataagg ggttggatgc agaaattttt gcagttccag ctcctgaagc agaagaaatt
     2341 gtagcaacaa aagaagtaaa tgtgttgctt ttaggccctc aagttcgcta tttactaggg
     2401 gactttcaag aaaaactaaa agatagacag attcctgtgg cggttattcc gatgacagat
     2461 tatggaatga tgaatggttc taaagtctta gatttagctg aaagtttatt agactaagat
     2521 tgaggagaat gctatgaatg aaagtaattt agaatctgca atggggctaa ttatgtatgg
     2581 tggggaagcc aaaagtaatg ctatggaggc tattcaggca gcaaaaaaag gggatttctc
     2641 taaagccaat cgaagattag ctgatgcgaa tgctgcctta ttacaggcgc ataaggctca
     2701 aacagaaatg ttgacaaaag aggcacaggg ggaagaaaca tcaattagcc tcttgatggt
     2761 acacgcgcaa gatcatttaa tgacgagtct gacctttgtt gacttggcga aagaagtggt
     2821 agaagtatac gaacgatttg aaaaaaatta ggaatttgct atgaatacaa tgttggataa
     2881 aatgcaagaa aaactttctc caattgcaat gaaagttggg aatcagaagt ttttagttgc
     2941 tttacgtgat tcatttgtgg ggactatgcc tgttattatg acaggttcca ttgctttgtt
     3001 attaaatgct tttctagtgg atttaccaca acaatttcac ctagaaagta ttacgaaaac
     3061 ctttcagtgg cttgttgaca tcaataattt ggtattcaag ggaagtatac caattgtttc
     3121 cttattgttc atctattgct tgggagtgaa tatcgctaag atttataagg ttgatacagt
     3181 ttctgctggt ttggtatcgc ttgcttcgtt tgtcatttcg attggaagta cagttacaaa
     3241 gagtttccct ttggcaaatg taggagatgt gaaattagat caaatcttac aaggaattga
     3301 taatctagca tttgatggta aaaatctgat ggtaactatt gggaatgtga ttccaggaaa
     3361 ccatattaat gccagaggct actttacagc catgatgatt ggatttttag cctctattat
     3421 tttctgtaaa gtaatgaaaa agaactgggt aatcaagtta ccagattcag ttccccctgc
     3481 gattgctaag ccgttcactt ctatcattcc aggatttatg gcgatgtata tagtagccat
     3541 cttgacttat gttttccatt tacttagcaa tgacttattg attgattggg tttacaaggt
     3601 gttacaaacg ccattactag gtttgtctca aagtttcttt gcagttattc tgatgatctt
     3661 tttgaataag ttattctggt tttttggtct ccatggagga aatgtattgg ctcccatcat
     3721 ggaagggctg tttggagttg ctatgttagc gaatctggat gctttccaaa aaggtgaacc
     3781 gattccttat atatggacaa gtgggtcttt tggggcgttt gtctggtttg gaggattagg
     3841 attagtactt gctattttaa ttttttcaag aaacagtcat tatcgaaaag ttgctaaact
     3901 tggtctagca ccagttctgt ttaatattgg tgagccggtc aattatggtt taccagttgt
     3961 cttgaatcct ttgctattta taccatttgt acttagcccg gttttcatgg caacggtagc
     4021 ttactgggca acaagctggg gtcttgtttc acctgttaca caaaacgtta cttgggtaat
     4081 gcctccaatt ttatatggtt tcttctctac agcatttgat tggcgtgcca tcatcttatc
     4141 agttgtttgt ttgattatta gtgtcttgac ttatttccca tttgtgaaaa tggcagataa
     4201 aactgaattg agttaatggt cttacttgcg ttttttgtga taaaatagaa atagattacg
     4261 tgtaagatga gttaggtgta ggatttctta tctccactaa aattgttatt agacaaaggt
     4321 ttataattta ttgaagttgg aatagtacac tgtaacttct aaaacagtac tagaaaatga
     4381 tttgaatttc ctaatcgatt tagtcatatt ttagttcatt tttctataaa acataacaag
     4441 aatgttattg ttttatatag agagattgat atagaaaggg gtgcagtaaa ggtagatatc
     4501 ttcttgtgcc tcttttgcca tattagaaag gagattttat ggttcagaca aaacagccaa
     4561 atattatttt gattgttgta gatcaaatga gagcagacgt cttatccttg aatagtaagg
     4621 ataagctagt tagcactcca acattagata tgatggctag tgtaggttat aattttgaaa
     4681 atgcctattc tccagttcct tcttgtgttc ctgctagggc agctttattg actggcttag
     4741 accaagataa aagtggacga gttggttatc aagatgaggt gccttggaat tttactaata
     4801 ctcttccaaa agtctttaaa gatatgggtt atcaaacaga gtgtattggt aagatgcatg
     4861 tttttccttc cagacagaga cttgggtttg atcatgtctt acttcacgat gggtatctac
     4921 atgttgatag aaagtatgat aaggcttatg gaagtcaatt tgattatgct agtgactatc
     4981 tagccttttt aaagggtaaa gttggttatg atgttgattt gattgatgac ggaatggatt
     5041 gtaattcttg ggaagctaga ccttgggata aagatgagaa gttacatcca acaaactggg
     5101 ttgtgagtga gtccatttca tttttacaaa gaagagatcc aacggttcct ttttttctca
     5161 aaatgtcttt tgaaaaacca catgctccat taaatccccc aaaatactat tttgatatgt
     5221 atatggaacg cttgcctcaa tttctcgatt tgcatatcgg gaattgggaa gtattagaaa
     5281 agcaaattcc gtctatttat gctttaagag ggaaattaaa ggaagatgat caaagaagaa
     5341 tggttgctgc ttattttgga ttgattactc atatagacca tcaaattagt cgctttttga
     5401 ctgccctaaa agaatttcgt catgataaag atacgattat ctggtttgtt tcggatcatg
     5461 gagatcagct tggtgaacat tatctgttta gaaagggata tccttatcag ggaagtatcc
     5521 acattccttc gtttatttac gatccggctg gattgatagc tggtaatagg ggaacaatca
     5581 agcaattagt gaaaattcaa gatatttttc cttcactcgt ggatttggca ggaggaacta
     5641 ctacagatga actagatgga cggagtgtta agaatttatt atttggacag tacgaggggt
     5701 ggcgaacaga atttcatggt gaacatgctt taggaaaaga ttctagtcaa tatatcttga
     5761 cagaccagtg gaaatttatc tggtttcctg ttttaaatca ttatcagtta tttgatatga
     5821 aaaaagatcc gcatgaaatg aatgatttgt atccaagtga aaaataccaa cctattgttc
     5881 gtcagatgaa gaaaaaatta gtagactttc ttagatatag agaagaaggt tttgttgtgg
     5941 atgaagagtt agttcctgtt gaactttcta aaataacgcc aactctaacg aaaacggggg
     6001 atagtcaatc atgaaaatga aaaaaatcaa gggtgggaca tttatgatgg gaacaaattc
     6061 tgaagagggc tttttagatg attttgaagg tcctcaagtc gctgttagtg taaaggattt
     6121 ttccattgcg gatactccag ttacgaatca agaatttgct caatttgtga aagaaacagg
     6181 ctataaaaca ctagctgagc gacaagagtg gtcttttgtt tttatattgt tcgttccaga
     6241 ggcagaaagg gagggatatc ctcatcctgc tgggactccg tggtggttac aagttccgaa
     6301 cgcttgctgg aaacatccct acggtgagaa tagtaatcta gtgggtttag aagaccatcc
     6361 agtagttcat gttgctttag aagatgcatt ggctttctgt aattggagcg gaatgtcttt
     6421 accgactgaa gcacagtggg aatatgctgc tagaggagga agacaatctg aatatccttg
     6481 gggagatact cttttagaag gtggatatta tcatgccaat acttggcaag gaagatttcc
     6541 ttatgaaaat actgccttag atggatttat aggaacggct cctgtctatg aatttttacc
     6601 taatgatttt ggtctatatc aaatgattgg gaatgtttgg gaatggtgtc gcaatccgag
     6661 atatacctta ttagctagtt ttaatgaaga tgactatgag ttaccaaaat atgggataca
     6721 agatgaggag tatgctatca gaggaggttc ctttttatgt cattgttctt attgtaatcg
     6781 ataccgagta gctgctagaa atggatgtat ttctacttcc actagtagcc atctaggttt
     6841 tagatgtttg aaagaatagg atggacttaa aaagtggttg agattattta ttttctaatc
     6901 attataatag ctagtggatt gggttctata tcaggcatgg gtggtggaat tataattaag
     6961 ccacttatgg atagttttgg ataccattcg gtcagtgata ttgcttttta ttctagtttc
     7021 tctgttttta taatggcgat tatttcaaca atcaaaagat tttcacaaag taaagagata
     7081 aaatggagat tgatttttac ggtatccttt tcttctgttt taggaggatt tctaggtcat
     7141 cttatttttc aagttttgtt atctcagtta tcagtacggc tagtatccat tgttcaaatg
     7201 attttactat ttgtgatgct acttgtatca tttgttttaa cagattttaa aaaaacttat
     7261 caatttgata agataggatt ctatatgatt tgtggtcttc tattgggctt gatttctagt
     7321 tttttaggga ttggtggtgg tccgctcaat gtatctttat tgatggtgtt tttttctatt
     7381 tcgataaaag aagcaacgat gtattctctt gcaattattt tcttttccca gttgtctcat
     7441 ttggctacaa ttgttgtggt tacaggttta aatcagtatc atttagcacc tgttccagtt
     7501 atttttcttg cttctatatg cggaggggta ttggggacgg ttgtatcaaa agtcttacct
     7561 gaaaattggg taagatactg ttttaaaggg atgttattct ttgtcatggg aatgacttta
     7621 tataatttat ttcatatttt gtaaggtcag tgtgaaaata tttaaataga cttcctgtaa
     7681 aaactggatt taacgccctc catttgtcaa attaagctag acagtcttac caactcagaa
     7741 aatacctgat gaggtatttg gtatccaaag gatttaggtg ggatgtgatt tcttgaggct
     7801 gggaaaaagt ctttaaaatt aaaaaatgta taatatcagg tgttggaaaa actttgatac
     7861 tatgcgtttt attgtgggaa tatttatttc attttctcct gaaattgagt ttttacccag
     7921 cctaaaattc ttgactgact tcgttgaaat ctgtctgctt tggcaagtca tgacacctta
     7981 aaagtctatt tgaatgttcg ttgagacacc gctgtcttgg acatcctaga ttcgcaaaaa
     8041 agctctcact atcgtgatga ttggaaatat ctttccattt tgaaaactct tttccacagt
     8101 caaacgtaat agatttaaag aggttcacta gaaattgtgc cagccaccct tggatggatt
     8161 ctgccatatc ctttgcctta cgactcttgg tcttcaaact gacaatcaat tgactatacc
     8221 tgttcgctca caaataggag agaacttttt acgaaaatct aatgaatatg ccacaagaac
     8281 attataccgc aacgtgtact atttttggtt cattttacta tagaaactat tgaagcacct
     8341 gtacgaaaat atagtagatt gaaactagaa tagtacacct ctacttctaa aacattgtta
     8401 gaaatcgatt tgactgtccc gatcgattcg tcctgttatt atttcatttt actatacatt
     8461 atgaaaaagg ggagatagaa agcaaacagc cttgaaatca atgttgactg cgattatgaa
     8521 cctgaatcag cccctcaaaa gggactgtat atgaatgaac gttaccagtg tttaaaaact
     8581 aaagaatatc aggcactttt atcttccaag ggtagacaaa ttttcgctaa acgtaagatt
     8641 gatatgaaat ctgtctttgg gcagataaag gtttgtttgg gttataagag atgtcatctg
     8701 agaggtaagc gtcaagtgag aattgacatg ggattcatac tcatggccaa caacctgctg
     8761 aaatataata agagaaagag gcaaaattaa aaagctagag ttccgcaatt gggaatctct
     8821 agctttttgt tttctgagaa tcatcttgac tcagactctt ttgactaatg ttaccaaaaa
     8881 agataaagta acttttaacc ttatttatcg tcgccactca acatgttttt aacaccttct
     8941 acagcacctt ctacagcgtc tttagcgtct tcggcaactt cttttacttt agaaacaact
     9001 ttttcagctg ctccttcttt ttccattttt tcatcaccga tggctttccc aacaccttct
     9061 ttaatagaac ctttagcttg atttaatttt tcttctactg acatgataat ttctcctgtt
     9121 atatttattt tatcttagtt tacacgagtg ttttcgtgag atactacacc atttgctgca
     9181 cctttaacag cttctacacc ttcgctaact ttttcttgaa cagttgagaa accagatcca
     9241 agaccagatt tagctttttc gaattgttct gaagtgaatt ctcctgttga ttcagcaacg
     9301 tcagatacgc gatcttgaag gcttactgag tctgcttcat gctgttcttt agttttgatg
     9361 tcgacaacgt ttacgttgat ttcaacaatt tccaagtcag tcattttagc aacttctgaa
     9421 gatacgattt ctctgatttc tgaatataaa gctggaacat ttttttggta ctcaacaata
     9481 acgtttaagt caactgcaac ttgtgtttta ccaacttcta cgttaacacc acttgttacg
     9541 tcatcgctgt taacgatttt ttctttaaga tttgagaaga aaccaccatc gattcccaaa
     9601 agacctgaaa cgttttctag tgaaagacca atgatttttt ggataacttt atcttcgtaa
     9661 gtaagttccc ctttgatttc gtgagctaca acagtagcat ctttcttttc tacgttagtg
     9721 tttgtgtttt tttcgtttga catatgaaac tcctttaatt aaattagtaa tttttatttt
     9781 tttatttatc tatatagttt ttttcgatat ataatccagc tgcaactccc agtgctccta
     9841 aaatcaatac aaatattgtt ttgaagaagc caaaggagac aatcaaacaa gccagaaata
     9901 cgcctatgag accagcgata attggatatc gatattgttt aagccattcc attttttact
     9961 tccttacttc acacgactaa cagtcttttt gttttgaggt tttggttggt aattttttac
    10021 tgcaacttca agttttactt gacgctcaat accaaaaaac tgcttcaatc cattagttat
    10081 ttcattttga attatttggc atctgtcagc gatgttgtct gaaggaagaa ttttaccttc
    10141 tacatgaacg aaacatttat tttttcgtaa atttacatga acagttgggt tcttgatcaa
    10201 tctatgatca ctcaccaaac ttctaacaaa accttcgatt gccgaattct ttaattttaa
    10261 tgtatcgttt ttagtttcaa gttggatttc caagtaacgt ttaggataaa acatcacaac
    10321 taaaatggat aataaaacta aagttgatag aaccactgtc ccccaaaaga catatctagc
    10381 aagatagaat tcaactacgg agttctgtct ccagctaagt agatgaatac ctagatcact
    10441 aacttgatga taatctatca aaacaggaag gaaaattgtc aagattaaaa tacagaaaat
    10501 aatgaaacat attttctttg cttttgacat atacaatcct ttcgatttaa catttaaact
    10561 atttttcccg tcattgattt aaaaatagtt tgctaacttt actggcgaaa agtttacttt
    10621 ctacctgtaa agaatgacac tacagtaatc acaatcgctg cacctacaat agatgggagc
    10681 aaagccattc cagcgattga tggaccccaa ctacctaaaa gagattgtcc tgcatatgcc
    10741 ccgactaaac cagcgaatac atttgcgatg attcccatag aactactttt ttagtgattt
    10801 tacctgccaa gagaccaata agacctccag caataattga tcacaacact gcctaccctc
    10861 cttttttatt ttaatatcaa aaaatcaatt tctttgatta atactattat ataactttaa
    10921 tatagaaaag tcaattattt cgattgttat tattatataa tttttaaaat taaaaatata
    10981 atctttagac ttgaatttga ttctgtattc acgccctcaa tagacggtaa aataagaaaa
    11041 ttgtttatat attgtctccg tagtgttatt atacgaaata aaagatttta ggaaaagtcg
    11101 ttatatcatg ctatacctat tctttgtggt ataattgcaa gaggtttaat ccgataattt
    11161 ataaagagag aaagatattc atgagagatt tattatctaa aaaaagtcat aggcaattag
    11221 aattattaga attattattt gaacataaac gttggtttca tcgttctgaa ctagcagagt
    11281 tattaaattg tacagaacgt gcagtcaaag atgatctatc ccatgttaaa tctgcttttc
    11341 ctgacttgat ttttcattct tctactaatg gtatacgcat tattaatacc gatgatagtg
    11401 atattgaaat ggtttaccat catttcttta aacattcaac tcatttttcg attttagaat
    11461 tcatcttctt taatgaaggt tgtcaagctg agagtatttg taaagaattt tatatcagtt
    11521 catcttcgct ctatcgtatt attagccaaa tcaataaagt gattaaaagg caatttcaat
    11581 ttgaagtcag tctgacccct gttcaaatca ttggaaatga gagagacatt cgttactttt
    11641 ttgcacaata tttttcagaa aaatattatt tcctagaatg gccatttgaa aatttttcat
    11701 cagagccact atctcaattg ttagaattgg tttataagga aacaagcttt ccaatgaatt
    11761 tgtcaacgca tagaatgcta aagttgctcc tagttacgaa cctatataga ataaagtttg
    11821 gtcattttat ggaagtagat aaagattctt ttaacgacca aagtttggat tttttaatgc
    11881 aggcagaagg aatagaaggt gttgctcaga gttttgaatc agaatacaat atctctttag
    11941 atgaagaagt tgtttgccaa ttatttgtgt cttactttca aaaaatgttt ttcatagatg
    12001 aaagtctctt tatgaaatgc gtaaaaaagg atagttatgt tgaaaaatct taccatctat
    12061 tgagtgattt tattgatcag atttcagtca agtatcagat tgaaatggag aataaggata
    12121 atctgatttg gcatctgcat aataccgcac atctgtatcg tcaagagttg tttactgagt
    12181 ttattttatt tgatcaaaaa gggaatacaa tcaggaactt tcaaaatatt tttccaaaat
    12241 ttgtttcaga tataaaaaaa gagctttctc actatttaga gactcttgag gtttgttcta
    12301 gttcaatgat ggtaaatcat ctatcttata ccttcatcac tcataccaaa catttggtga
    12361 ttaatttgct acaaaatcag cctaaactaa aggttttagt tatgagtaat tttgatcagt
    12421 atcatgcaaa attcgttgca gagacacttt cttattactg tagcaataat tttgaactgg
    12481 aagtttggac tgaattagaa ttatcaaagg aatctttaga agattcacct tatgatatca
    12541 ttatttctaa ttttattatt cctcctattg aaaataagag actcatctat tcaaataata
    12601 taaacacggt ctcactcata tacttgttaa atgccatgat gtttattcga ttagatgagt
    12661 aagcaaaaat aacaaaaaaa cgctatttcg cgtttgaact gtacctcaaa agttagacag
    12721 aaaaaatcta atttttgggg tgtttttgtt aagaaaagac cttcaatcat ttaagcaaaa
    12781 tgtacatcta gatttatagc cctctaaaac tcttgctttt tttgtagaag atacgaaaaa
    12841 agccataaaa ccaaggcttt tcctgtttta tgtagatgtt tacacatgaa aattgaagta
    12901 ttttcaaaag ctaattggag tgattttatt catgatggga taaatgatct ggccaaaaat
    12961 gattgagaaa tagttgctta aaaagcattt gcatgatact atatattgaa aggaggtgat
    13021 aatatggtag aacaaagaaa atcaattacc atgaaagatg ttgctttaga agcaggagtt
    13081 agtgttggaa ctgtttcacg tgtaattaat aaagaaaaag gcattaaaga agtaactttg
    13141 aaaaaagtgg aacaagcgat taaaactttg aattacattc cagattacta cgctagagga
    13201 atgaaaaaaa atcgaacaga aacgattgca atcattgtac caagtatctg gcatcccttc
    13261 ttttcagaat ttgctatgca tgtggaaaat gaagtctata agagaaataa caaattactc
    13321 ttatgttcta tcaatggtac aaatagagag caagactatc tggagatgtt gcgtcataat
    13381 aaagttgatg gagtggttgc cattacctat agtccaattg aacattactt gacgtcagga
    13441 attccctttg ttagtattga ccgcacatac tcagatattg ccattccttg tgtttcatca
    13501 gataatgatg caggtggaag agaagcagct aaacaattaa ttagtaaagg atgtcagcat
    13561 ttagcctttg tgggcggaca taatacaacc attaatgaaa ccaaacgtcg tagaatttca
    13621 tttgaaaagt atgtccaaga gcataaaata cctcttagta tttttgattt ggatgagaca
    13681 gttactgact attatggaaa gctagagagt ttcttggaag aaaattcttc tatagatgga
    13741 atttttacaa tcaacgattt tacagctttg gatgtgattg aaatactaaa aaaaaatggc
    13801 aaacgtattc ctcatgatgt ccaaattatt ggatacgatg gaattaaaat ggctggagat
    13861 agagattatc tactttcaac tattgaacaa ccattggaag aaatggcaaa agaagcggtt
    13921 cgtattttgt ttgatataat tgatggaaag actgttaatt tgcagacaat cctaccagta
    13981 aaatttgttg aaggaaaaac aacaaaaaat gaaaataagt cttgacagaa agcgctatca
    14041 atgatagaat aaattcagat aaaaagattt atttttaaaa caaaaatgaa acgtttcaaa
    14101 aaagaaataa aaagacagcg ccaagcgcta tcttttctag aaaaaaatga aacgtttcaa
    14161 aaaagagggt tgctatgaat agcaaagcga agcaagtttc tctttgggaa agaatcaaga
    14221 aacaaaaact cttgttattg atgactgtcc ccggtttagt tttaaccttt atctttaaat
    14281 acatccctat gtatggggtt ttaatcgcat ttaaagatta caatccttta aaaggaattt
    14341 tagggagtga ttggattggt ttttctgagt ttacaaaatt catatcctct cccaactttg
    14401 gtatcttgtt agccaacaca ttaaaattaa gtatctatgg tttattgctt ggctttttac
    14461 caccaatcat tcttgcgatt atgctcaatc aactcttgag tgaaaaagtc aaaaaacgaa
    14521 ttcagctcat tttatacgca ccaaacttta tctcagtcgt tgttattgtc ggtatgattt
    14581 tcctcttctt ttcagtggga ggaccaatca acaattttct ttctatgttt ggaatgaagg
    14641 ctgacttctt gacaaatcca gacttcttta gacccttata catctttagt ggtatctggc
    14701 aaggaatggg ctgggcttca acgctctaca cggcaacatt ggtaaatgta gatccagcct
    14761 tagtagaagc agctcgactg gatggagcca atatcttcca acgaatctgg cacattgata
    14821 ttccagctct taagcctatt atggttatcc aatttgtttt agctgcaggt ggaattatga
    14881 atgtcggata tgaaaaagca ttcttgatgc agacatcgtt aaatttgcca acttctgaaa
    14941 ttatctcgac atatgtctat aaagttggtc ttgtatcagg agactattct tactcaacag
    15001 cggttggttt gtttaatgca gtgattaacg tagtattgct tgttgcagtt aaccaaatcg
    15061 ttaaacgcat gaataatggt gaaggaattt aaggaggaaa gtatgaaaaa ttcgattatg
    15121 gatacaaaat ttgatagacg tatcttactc ttaaataaaa tcattattgt ctttatcgtt
    15181 ttgatgactt tgcttccttt actttatatc gtcgtagcat cctttatgga tcctaaggtt
    15241 ctggttagta gagggattag ctttaatcca gccgattgga ctgtagaagg ttaccagcgt
    15301 gtattcagtg accaatctat tctaagaggt tttatcaatt ctctactata ctcttttgga
    15361 tttgcagctt taacagtctt gctatctgtg tttacagctt atcctctttc caaaaaagat
    15421 ttggtagggc gccgttggat taactacttc ttgattgtga ctatgttctt tggtggtggt
    15481 ttagtcccaa cttacttgct cgtaaaagaa ttgggaatgc tcaatactcc atgggctatc
    15541 attgttccag gtgctgtcaa cgtttggaat attattcttg ctagggccta tttccaagga
    15601 ttgcctgaag aattagttga agctgctgtc attgatggtg caaatgattt acagattttc
    15661 ttcaaaatca tgcttcctct tgcaaaacca attatgtttg ttctcttcct ttatgctttt
    15721 gtaggacagt ggaactcata ctttgatgca atgatttata tcaaggatcc aaacttggaa
    15781 ccattgcaac ttgtacttcg taaaattctc attcagagcc aaccaggtca agacatgatt
    15841 ggagcacaag cggctatgaa tgaaatgaaa cgtttagctg aattgattaa atacgcaact
    15901 attgtcattt ccagcttgcc attgattgtt atgtatccat tcttccaaaa atactttgat
    15961 aaaggaatta tggctggttc acttaaagga taaaaaaaga aaaaataaaa ggagttttct
    16021 catgaaattc aaaacattct caaaatcagc agttttgttg acagctagtt tagcagtact
    16081 tgcagcctgt ggctcaaaaa atacagcttc aagtccagat tataagttgg aaggtgtaac
    16141 attcccgctt caagaaaaga aaacattgaa gtttatgaca gccagttcac cgttatctcc
    16201 taaagaccca aatgaaaagt taattttgca acgtttggag aaggaaactg gcgttcatat
    16261 tgactggacc aactaccaat ccgactttgc agaaaaacgt aacttggata tttctagtgg
    16321 tgatttacca gatgctatcc acaacgacgg agcttcagat gtggacttga tgaactgggc
    16381 taaaaaaggt gttattattc cagttgaaga tttgattgat aaatacatgc caaatcttaa
    16441 gaaaattttg gatgagaaac cagagtacaa ggccttgatg acagcacctg atgggcacat
    16501 ttactcattc ccatggattg aagagcttgg agatggtaaa gagtctattc acagcgtcaa
    16561 cgatatggct tggattaaca aagattggct taagaaactt ggtcttgaaa tgccaaaaac
    16621 tactgatgat ttgattaaag tcctagaagc tttcaaaaac ggggatccaa atggaaatgg
    16681 agaggctgat gaaattccat tttcatttat tagtggtaac ggaaacgaag attttaaatt
    16741 cctatttgct gcatttggta taggggataa cgatgatcat ttagtagtag gaaatgatgg
    16801 caaagttgac ttcacagcag ataacgataa ctataaagaa ggtgtcaaat ttatccgtca
    16861 attgcaagaa aaaggcttga ttgataaaga agctttcgaa catgattgga atagttacat
    16921 tgctaaaggt catgatcaga aatttggtgt ttactttaca tgggataaga ataatgttac
    16981 tggaagtaac gaaagttatg atgttttacc agtacttgct ggaccaagtg gtcaaaaaca
    17041 cgtagctcgt acaaacggta tgggatttgc acgtgacaag atggttatta ccagtgtaaa
    17101 caaaaaccta gaattgacag ctaaatggat tgatgcacaa tacgctccac tccaatctgt
    17161 gcaaaataac tggggaactt acggagatga caaacaacaa aacatctttg aattggatca
    17221 agcgtcaaat agtctaaaac acttaccact aaacggaact gcaccagcag aacttcgtca
    17281 aaagactgaa gtaggaggac cactagctat cctagattca tactatggta aagtaacaac
    17341 catgcctgat gatgccaaat ggcgtttgga tcttatcaaa gaatattatg ttccttacat
    17401 gagcaatgac aataactatc caagagtctt tatgacacag gaagatttgg acaaaattgc
    17461 ccatatcgaa gcagatatga atgactatat ctaccgtaaa cgtgctgaat ggattgtaaa
    17521 tggcaatatt gatactgagt gggatgatta caagaaagaa cttgaaaaat acggactttc
    17581 tgattacctc gctattaaac aaaaatacta cgaccaatac caagcaaaca aaaactagag
    17641 gttgattatg ggagataaga aatacacagt agaaaaagcc aatcgtttta tagcagaaaa
    17701 taaacatctc gttaatactc aatataagcc tgaagaacat ttttcagctg agattggttg
    17761 gatcaatgat ccaaatggat ttgtctattt tcgtggagaa taccatctct tttatcaatt
    17821 ctatccatat gatagtgttt ggggacctat gcactgggga catgctaaaa gtaaggactt
    17881 ggtgacttgg gagcacttgc cagtggcact tgctcctgat caagattatg accgaaatgg
    17941 ttgtttctca ggctctgcca ttgtcaagga tgatcgcctc tggctcatgt acactgggca
    18001 tatcgaagaa aaaaccggtg tccgccaagt gcaaaatatg gcattttcag acgacgggat
    18061 tcactttgaa aagattgaac aaaatccagt tgcaacagga gcagacttgc cagatgagtt
    18121 gattgctgct gatttccgtg atccaaaact ctttgaaaaa gatggacgct attactccgt
    18181 agtagctacc aaacacaagg ataatgtggg ctgtatcgtt ctactagggt ccgataacct
    18241 agtagaatgg cagttcgaat ccatcttttt aaaagggaga gaacaccaag gctttatgtg
    18301 ggaatgccca gattacttcg agttagatgg gaaagattgc cttattatgt cacccatgcg
    18361 ttatcagcgt gagggagact catatcataa catcaactca tcgcttttgt tcacgggtaa
    18421 ggtagattgg ggagaaaaac gttttatccc agaatcagtt caagaaatcg atcatggcca
    18481 agacttctat gcgcctcaaa cattgttgga cgatcaaaat cgtcgtatcc tgattgcttg
    18541 gatgcagaca tgggggcgta cccttccaac ccatgaccaa gaacacaaat gggcatgtgc
    18601 catgacttta cctagaattc taagattgga agatggcaaa ctaagacaat tccctgttaa
    18661 aaaaggccaa tatcaaatcc aaatagataa agattgtcat taccacttag gaaatgatac
    18721 agattatctt gaatttggtt atgacagtaa tgcgcagcaa gtttacattg atcgtagcca
    18781 tcttattcaa aaaattctag gtgaagaaga acaggacact agtcgacggt atgtagatat
    18841 tgaagctaaa gaattggaag ttgttctaga taaaaattcc atcgagattt ttgtcaatca
    18901 aggtgaagca agcttgactg caacttatta cttaacggtg ccagctgagc tatcacgaat
    18961 tgattaaaaa ttaagttatt tctcctaaag aaaaagttct ctttctaaaa tagtggaaag
    19021 aggacttttt gtgttttggg tatataagct tagtttatgg tatttgtaaa attggtgttg
    19081 gattatgatt taagctagtt ttctaaagaa tttgaaaaaa attttattta agcaaaaaaa
    19141 ccttggttcc aaggcttttc ctgttgtatt tagatgcccc ctacagggat cgaacctgtg
    19201 acccacggat taagagtccg ctgctctgcc agctgagcta aggaggcaaa gaaaaagctg
    19261 tattggtgcc gaaacttcac ggtttgtatt gaacccgcgc aattaagcag gtgggcaact
    19321 cgctctaact gaagctgttt ccgtgtgaga cggcctacat gctgttagaa gacttttgtt
    19381 tccctaataa tacaaaaaat agtcggtcaa cacttaagtg tgaagtcgta caccacagcg
    19441 tttctatact tatatgatac cactttttca aaaaaaatca agaggaaagt gcaatttttt
    19501 gaaaaggatt tcagattttt cgcaaacgat cgatagcttc ctttctttga gccaaagccc
    19561 gttcatattt accagtatct tctgcttgga aatagtgatg attacgaatt ttttctggca
    19621 gatagtcttg cttgacccaa tttccaggat agttgtgtgg atagagatag tcttgggcat
    19681 tccccagttc cttgcttcca ctgtagtgcc catcacgcag gtgtcgcgga ataggcaagt
    19741 gccctgatgt tttgaggtca gcaagtgcct tatccatagc tacataggct gagttggatt
    19801 ttggagaaag ggccaaatca atcacgacat tggcaatgag aatgcgggct tcggggaaac
    19861 caatcctttg tgcagcatcc agagcagtca cggtatgaat ctgggcctca ggattggcta
    19921 agccgatatc ttcataggcg ataacagtca agcgacgagc gagactaggc agatccccag
    19981 cctcaatcaa gcgggcagta tagtggagac tggcatccac atctgagcca cgaatagact
    20041 tttgcagggc agatagaaca tcatagtgac cgtctccatc cttgtccata gtgatgtagc
    20101 ttctctgaag actattttcc atgatgtcta aggtgatgtg gcgaatgccc tcgtcattct
    20161 caggggtaga tagaacagcc aagtccagtg agttaaaggc agagcgaagg tctccgtttg
    20221 tagaggttgc gatgaaatcc agcgcatcct catctagttc tattggaaaa tcaaaaccac
    20281 gttcagggtt acttagagct atctgcaggg cctctttgac gtcttggtta gacagaggtt
    20341 ccaactcgaa aatttgaact cggctacgaa tggcaggagt gacagagaag aaaggatttt
    20401 cagtcgttgc tccaatcatg atgaccagtc cactttccaa gagaggcaag aggaagtctt
    20461 gcttggtctt atctagtcga tgaatttcgt ctagcaatag gacgagacca ccagaaaatt
    20521 tagcttcttc cgagatttct tgcagtcgct ttttactatc aactgtcgca ttgaaagttc
    20581 gaaaggcata cttggtcgtt ccagcgatgg cagaggcaat actggttttg ccgattccag
    20641 gagggccata tagaatcatg gaggacaggc ggttggcttc caccatgcgg cggatgattt
    20701 ttccaggtcc gaccagatgc tcctgaccga tgacctggtc gatggtttta gggcgcatgc
    20761 gaagcgcgag attgtctggc atagcagtcc tttctaacgt ggatttgagt agaatgactc
    20821 atctactata tcttactatg tccattctag cctattagtt gtgatatttc aatggttttg
    20881 taataatcag ggagtgagat agaatctttt ttactattta atttaatgag gagaggtatc
    20941 agcatgagag atttgatttt ccttaaagct caaaatagga tagttgagcc taaagaagtg
    21001 gaagtgctga cttgagaaat aatattgctg aatgtcattg tatgaactat aatgaaaaga
    21061 gaggtgataa gcaatggaaa tgatggacca agtcaggaaa ttttgatttt tacaaaacaa
    21121 attcgtcatt ggattcttag tgatcaagtt atttcaggga aaagaaaact tttcttccgg
    21181 gaagatactc caaaagagat tttagatttg tacgaaaaca ttaaatctaa acttgatttt
    21241 gcttaccaag aagtttattc taataatggg ttgaaaaaat atgaaaaata gaataattga
    21301 tgtttttgaa gtagtaaatc gcatccttgt actaactgtt gaaaatcctg atttcgaaga
    21361 cttgagagtt aatcatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc
    21421 tgtacttgag tacggtaagg cgacgttgac gtggtttgaa tttgattttc gaagagtatc
    21481 agtttgtaaa aattggagat aaaaaatata gagtacgcag tggtcctatg attcattcaa
    21541 ctccgcctca atctgtctta gatcgagata cttttacaat tgactataca gatgatgaat
    21601 tgctcgataa agaagcagtt tttactactc attagaaaaa taggtctgaa taaattggtt
    21661 tcccttagaa ccacatctag gggcttttat gtataataga ataataagta tcactccttt
    21721 acaatacgtg taacacgtgt tataatggtg ttgtcaggag gtaaaagcgc tatacctatg
    21781 acacaaaaag agatggttaa actccttacg gcccatggtt ggataaagac tagaggcggt
    21841 aaaggctccc atattaaaat ggagaagcaa ggggaaagac ctatcacaat ccttcatggt
    21901 gagctgaata agtacactga aagagggata ggaaagcaag ctgggttgta aaattcagtc
    21961 cctgcttttt gatatggagg tagtgaaatg ttagttacgt atccagcttt attttattat
    22021 gacgacacag acggaacaga agcgacttat tttgtccatt tcccagattt tgaatactca
    22081 gctacacaag gagaggggat ttctgaggct ttggctatgg ggtcggagtg gctagggata
    22141 actgttgcag atttgataga gagtgatgga gagttacctc agccatcaga tatcaatagc
    22201 ttgtctttaa ttgataatga tccttttaaa gatgatgaag atttcgtgtc aacctatgac
    22261 cttgataaat attttatttc tatggtatct gttgatgtat cagaatacct aggaagtcag
    22321 gaacccatta aaaagacttt gaccatacca aaatgggcag ataagttggg acgagaaatg
    22381 ggacttaact tttctcagac tttgacagac gctattgcag ataagaaagt tcaagcctaa
    22441 gattaagcgt ggtatcgtgg taatagtcaa taaaaaagca cgtccacttg tgctagttac
    22501 tcgcctattg attttataga tttattagcc ctttcgcggg ctttttatat tgatttttat
    22561 gagaaatgaa gaaatcagac ttttaagaaa atcactgata ccaagggttt aaatgaggta
    22621 atatggtata attaggacat aaaataattt tgtggtaaga tggtagtatc tattttagca
    22681 tatttccgag caatcggggc gattaaagag tcgcatagaa agaggacaaa atggcaacat
    22741 acggattttt agatgtttta gaggaagagt tggacaagaa ctttcccttt gactttgaga
    22801 ttagctggga caaacgcaac catgcggtag aagtgagttt tctattggaa gcacaaaatg
    22861 ctgcaggtgt ggagatggtg gatgaagacg gagaggtttc atcagatgac attctttttg
    22921 aggaagcggt ccttttctac aatcctgcta agtcaaccgt caatgcagaa gactatttaa
    22981 cggttatccc ttatctacct aaaaaaggat tttctcgcga gtttttagct tattttgccc
    23041 ttttcctcaa agatactgcg gaagttgggc tagataccct catggacttt ttggaagatc
    23101 cagaagcaga ggaatttgtt atggaatgga atcaagaagt ctttgaagaa ggaaaagttg
    23161 gcttggaaga gggagaattt tatccttatc caagatacta ggagttggtt ggaggtgtta
    23221 tgaagaaaat tgggacttat ttggtttatg tgctagctgt tgtctttatt atgctagctt
    23281 ttgcttgtgg aacaatcgca tttgcagagt tggggtattc cgcagtttta gcctttactt
    23341 ttggttatgc cttcgctctt ctaagcatgt atttaatctt tattcttcat gagctgggtc
    23401 atgctttttg tggctacttg acaggctatc ggctggtggc ttttggatta ggacatttta
    23461 ttttgaccaa aaagtcaggc aggtttcatc ttagtagaac agccattctg aaaaatgttg
    23521 gtgctcaata cattggttta aaagaggatg aaagcgatca aagaatcatc ctgatgcttt
    23581 caggaggctt gatggttcat ctcggcttga tattattggc gatagtgttt ggatttttga
    23641 caagaagctg gtattttgca gggacttgga tttttcttaa tttatctttc ttcctaaata
    23701 acattttgcc agtcgacatc accgatggag caaaaatttg ggaattacta caacaccctg
    23761 aaaataccaa atacgcctac ctggtattga gacattctgc tcaaactttg ctggttcctc
    23821 aagaatatga tttgaaagac tttgttcaag cagttcctga ggatgcacga gggagttttg
    23881 cggatggtgt attaggtatg caaggtgaag tttccatttt ggaagggaag gaagaagtag
    23941 ctaaacagca gtttcaagca ttacttgaga ggacaactac tccgatgatg cagacagttg
    24001 cccaactatc cctgcttcat atcgccttgt tggaaggaga ttttgagcaa gcggagcaat
    24061 atgctagtat tcgacaggtc aaatcgtttc tgtctctcaa actgtccaat cttcaagtga
    24121 tacaagcctg gtatcaatta aaggtgaaga aagatgtaga tcgaactcgt aaggctctca
    24181 agattgctag acagaaaatg gatagtagtc gaatgttgag ggacgagaaa cgctattatg
    24241 aaaacttgtt agcagagctg gaaaaggaaa tgttagaagg aactgaagat ggaactagaa
    24301 atttctgatt tcctaggctg taagattgct ttgttttgtg gggataagct tttgactatc
    24361 ttacgcgatg ataaggcaag cattccctgg gccaatatgt gggaactgcc aggtggtgga
    24421 cgtgaaggtg atgaaagtcc ttttgagtgt gtagcgcgtg aagtttatga agaactgggc
    24481 attcatctga ctgaagattg tctgctttgg agtaagattt acccaagtat gctttttgca
    24541 gacaaacagt ccgtttttct agttggtcag ttgacacaga accagtttga cagtatcgta
    24601 tttggagatg aaggacaggg ctatcagctg atgaatgttg aggaatttct tagttccagt
    24661 caagttgtgc ctcagttgca agagagatta aaagattatt taaaagtaag tgattagaaa
    24721 ggatggttcg gttaaatttc taaactgaac ccgccctaaa cacggtgcca aaaagataaa
    24781 cttctcttag acacaaacgt cttcagagaa tttcctattt tggttttgtg ttttacgggc
    24841 ttggtatctt aataatggaa acatggcaag agttaaaagt tacagtgaag cgtgagggag
    24901 aggagttggt ttccaatctc ttgattgagc taggagcgca aggagtcgca atcgaagaca
    24961 gtatggacta tatgggaaat gtggatcgtt ttggcgagat tttcccagag gtggagcagc
    25021 aagaagaaat cgtagtgaca gcctactacc ctgacacggt ggatgtgaca gtggttgagg
    25081 cggacttgca ggctcgctta gcagaattga cggattttat ggatttgggt gaagtcaaga
    25141 tggggacgac tgccttggct gaggaagact gggcagacaa ctggaagaaa tactatgagc
    25201 cagctcgtat cactcatgat ttgaccatcg ttccctcttg gacagactat gaggcgactg
    25261 cgggagaaaa aattatcaag ctagatcctg ggatggcttt tggtactggg acccatccaa
    25321 ctaccaagat gagcctcttt gccttggaac aggttcttcg tggtggcgag acagtgctag
    25381 atgtggggac tggttcaggg gttctctcca ttgctagctc gctacttggt gccaaggaaa
    25441 tcttcgccta tgacctagat gatgtagcag ttcgtgttgc tcaggaaaat attgaactta
    25501 accctggaat ggaaaatatc cacgttgctg ctggagactt gcttaagggt gttgagattg
    25561 aggcagatgt gattgtagct aatatcttgg cggatattct cattcatctg acagacgatg
    25621 cctatcgttt ggtcaaggat gaaggctacc tgatcatgag tggcattatc aaggacaagt
    25681 gggacatggt gcgcgagtcg gctgagtcag ctggattttt ccttgaaacc cacatggttc
    25741 aaggggaatg gaatgcctgt gtctttaaga aaaccaagga tatttctggt gtgattggag
    25801 gctagcatgc agcagtattt tgtaaaaggc agtgctatct ctcctgtcac tatcgaggac
    25861 aaggaaacca gtaagcatat gtttcaggtt atgcgcttga aagaagagga tgaggttacc
    25921 ttagtctttg atgatggcat caagcgcttg gcgcgcgtgc tggatatgga aaatcgtcag
    25981 tttgagttgg tccaagaatt aaatgacaat gtggaactac cagttcaagt gaccatcgca
    26041 tctggatttc ccaagggaga caagctggag ttcatcgctc aaaaagtaac cgaactgggt
    26101 gctagccaaa tctgggcctt tcctgcagac tggtcagttg ccaagtggga tggcaagaaa
    26161 ttgggtaaaa aagttgaaaa actagaaaaa attgcccttg gagcagccga gcaaagcaag
    26221 cgtaatattg taccaagtat taaacttttc gagaaaaaag cagattttct aactcagctg
    26281 gaccagtttg actctatcat agtagcctat gaagaatcag ctaaagaagg agaagccgct
    26341 gcgcttctgc aagcagtcac tggtcttgaa acaggagcca aactgctctt tatctttggt
    26401 ccagaaggcg gtctctcacc tgcagaaatc gaaagttttg aagctaaggg agccgttttg
    26461 gtaggcctag gtcctcgtat tttgcgagca gaaacagcac cgctttacgc cttatcagcc
    26521 cttagtgttt tagtagaatt agagaaataa gaggaagaaa atggaacaaa aacaccgttc
    26581 agaatttcca gagaaggaac tttgggattt aacagctcta taccaagacc gtgaggattt
    26641 cttgcgtgca atcgagaaag ctcgcgaaga catcaaccag tttagccgtg attacaaggg
    26701 caatcttcac acttttgagg atttcgagaa ggcctttgcg gaattggaac agatctacat
    26761 tcagatgagc catattggca actatgcttt tatgcctcag acgacggact atagcaatga
    26821 cgaatttgca aatattgctc aagctgggat ggaatttgaa acagatgcca gcgtagcctt
    26881 gaccttcttt gacgatgcct tggtggtagc agacgaggaa gtcttggacc gtttgggtga
    26941 attgcctcac ttgacggcag ctattcgtca ggccaaaatc aaaaaagccc actatctagg
    27001 ggttgatgtg gagaaggcct tgaccaatct cggtgaagtt ttctatagtc cgcaggacat
    27061 ttatactaag atgcgagctg gggattttga aatggctgac tttgaagccc atggcaagac
    27121 ctataaaaac agctttgtca cctatgagaa tttctaccaa aatcacgagg atgctgaggt
    27181 tcgtgagaaa tccttccgtt ccttctcaga gggacttcgt aagcaccaaa atacggctgc
    27241 agcagcctat ctggctcagg tcaagtctga aaaactcttg gctgatatga agggatacga
    27301 ctctgtcttt gattatcttc tagctgaaca agaagtggac cgtgtcatgt ttgaccgcca
    27361 gattaacctc atcatgaagg actttgcacc agtcgctcag agatacctca agcatgttgc
    27421 caaggtaaat ggtcttgaaa agatgacctt tgcagactgg aaattggact tggacagcgc
    27481 cctcaatcct gaagcgacta ttgacgatgc ctatgatttg gtcatgaagt cggtagaacc
    27541 tttggggcaa gaatattgtc aggaagttgc tcgttaccaa gaagagcgct gggtggactt
    27601 tgctgctaac agtggcaagg attccggtgg ttatgcggcg gacccatatc gcgtacaccc
    27661 ttatgtactc atgagctgga caggccgttt gagcgatgtc tataccttga ttcatgaaat
    27721 cgggcattct ggtcaattca tcttttcaga caatcaccaa agctatttca acgcccacat
    27781 gtcgacctat tatgttgaag caccgtcgac cttcaatgaa ttgctactca gtgattactt
    27841 agagaaccag tctaatgacc cacgtcaaaa acgcttcgct ctggctcatc gcttgacaga
    27901 cacctacttc cataatttca tcacccacct cttggaagcc gccttccagc gtaaggtgta
    27961 tacattgatt gaagaaggag aaaccttcgg agcaagcaaa ctcaacagca ttatgaagga
    28021 agttttgaca gatttttggg gcgatgccat tgaaatcgac gacgatgcag ctttgacttg
    28081 gatgcgccaa gctcactact atatgggctt gtatagttac acttactctg ctggtcttgt
    28141 catctcgaca gctggttacc ttcatcttaa aaactcagaa actggagctg aagactggct
    28201 caatctcctc aaatcaggtg gtagcaagac accacttgag tcagccatga ttatcggtgc
    28261 tgatatttca acagacaaac cactccgtga taccatccaa ttcttgtctg acacagttga
    28321 ccagattatc gcctacagtg ctgagttggg ggagtaaggg gatagagagg ttgttataga
    28381 atgggtatgg acagttattt gcttaaaagt ccatgtttaa atcccccatt ccttttcgag
    28441 gaattctttg cccttctctg taatggtaag tgaacgtggc gtttgtgcag ggatgaccaa
    28501 ttgtttttca ctgaaaaatt ctaaaagagc attgccgaga gctccgccga catgattttt
    28561 acgttcgctc caatccaaac atttagggca aaatttccgt tttttctttt tcaattcatc
    28621 cgtatcaatg tgtaattttc tttggaaata agacttccca gcttcagtga gttggaagtc
    28681 tttttctgat tcgctgagga gattttcttg caagagataa ttggtaatgg aaatgccaag
    28741 ctcaccagca atatggtcat agcaggtgcg agcgaccttt aattcctttt tgtgaatgtg
    28801 ttgtttataa cttttgacat cacgctgagg agagtagaag ctgagaaatt ccagcatttc
    28861 tgcaatggca gcacttttta aagaataata atgaaaacgt ccataggttt gtagagtggt
    28921 tacctgcgct tcggtaagta atttgaggtg atagctgaca gtatgttgct tgattttggt
    28981 aaagctggca atttcgttaa ccgtgtgagc ttttccatcc attagaatat ctaaaatgtg
    29041 catccgagaa gggtctgata agagttttgt gatgatgaaa atatctggtt ccataaaaat
    29101 tttctccaaa tttcatatat cgatgatttt ctatctttta ttatactata attaaagcac
    29161 aagaaaaata gattttaaaa atgttttact agagaatatt ttaaatttta ttgtctgagt
    29221 ttaaatggag gtaaaattac aaaagtaatt gcagcagtat ccacagttga aggacgttaa
    29281 tcttaagatt acattctcaa cattttttca aaagtgagat gaattaacaa agtatccaac
    29341 atgctctatt tgtgggggaa agaaagagtg aagaagttaa gtgttaaaaa tctaaaaaag
    29401 caatatggtt cttatgaagc tgtcaaggga attagctttg aattgggaga cggagagtgt
    29461 ttgggtatct tgggaatcaa cggtgctggc aaaacatcca ctttaaagat gatttactca
    29521 ctgacctcaa tttcctcagg agagattgat atcttggggc aaaatattga aaccaatcgt
    29581 cgtaagagta aatcttgtct gggtattgta gggcaggagg atatgctgga catgaccttg
    29641 aatgtttatg ataatctttt tgctcacggt ctatgttatg gtatctcatc tgtcgaactt
    29701 aggaagagaa tcgattctct cttggatttt gttcaactga gcaaacatgc gcaaaagatg
    29761 gtgaatcagc tgtcgggtgg gatgcgacga cgtcttgtct tggcaagagc tctcatcaat
    29821 cggcctgata ttatcatttt agatgaaccg acagttggtt tagacattca atcccgcaat
    29881 attatttggg ataaactttt ggaattgaag gaattaggtg tttctatcat tattacttcc
    29941 cactatatga atgagattga atatttgaca gatagggtgc tgatgctcca ccaagggact
    30001 atcaaagaag aaggaactgt agaagacttg ctcatcaagt atgatgctga caaccttgag
    30061 acgctttttt gggggttgac tgggacagag aaggaggact tgcatgttta agttatcatt
    30121 tcactccatc ggacacgttg tggtacgcaa ctacatgagt tttagaaatt tatttaaaat
    30181 ttcaattgtc cccaacctta tcgaccccct cttttatctt ttagcaatgg gatttggagt
    30241 tggtgcttat ttgacgcatg ttaacggtat gctctaccgt gattttgtca ttacaggttt
    30301 aattgctgcg actgccatgt ctgcggccac cgcagaaaca acggtcaatg cctttatcca
    30361 gtataagatt gaaaagactt atgatgctat gttgatgacg ccaatcaata cgaatgatat
    30421 tgtggtaggt caggctatct gggcaggtat tcgtgcagtg attttcggtg ggattttttg
    30481 gctgatttcc atgcttatca cagcgcattt tcatgtcttg atgttattga ttcctctgat
    30541 tttatttata gtgggttatt tgtttggtgt tttgggacta atctttacct acttggcgcc
    30601 gtctagggaa tttctgaatt actacaatgt tttggtaatc cgtcctcttt atatgttttc
    30661 agataccttc tttcccatta cttccttgcc cccaatactt ggtgatttga cttggttttc
    30721 tcccttgtat cacgctaccc gcatgattcg tattatatgg ggaggtgagg tgacaggttt
    30781 gtatcttcat cttatctggt tgatagcctt ggcgctcttg ataacggtgc ttcctatgta
    30841 tatgttacat cgtagatatt atagatagtc taattatttg tgatgttgta gtcatattct
    30901 aatttatact aaacgttatt cgaatttgga caggtatggg aactgtgcct atcaatattg
    30961 taatttatgg aagttgaaat agtacggttc agtttttaaa tattgttaga aattgtttta
    31021 aattccctaa tcaatttgta tagtttttat ttcactttat tataactagt ttttcgcaat
    31081 ttttgagaca ggaatgtgat ttttgtgata aggttctatc attacaagtt tatttgttgt
    31141 aatatggaat aaatcattta tatatctttt cagaaatatg ctgtttctct gaatataaat
    31201 gtctttttct ttttaactta attttacaaa ttggtaaggt catttaagac tgcctttttg
    31261 aacagttgct agaaatgtag aggtattgac catgtatcaa gatttactaa gaaaaatagc
    31321 agaagaaaaa ccaaattata accaggagga aatccagtgg ttgcttgatc atttgggaga
    31381 tccttctcca gaaattcgtg atgaccttgt ttttacaagc tttgctagag ggattcagga
    31441 agagctattt acacaggaac aatttcattt cattgctgaa ggggtttcat ctgatggagg
    31501 gttagataaa gagattgata agataggcct gccaacactt gaacgttctt ttagggcgct
    31561 tatttatgca actctcttgt ctgacgatgc caaccagcaa tcggtttttt atcaggaatt
    31621 aaatgcagga tttcgtaatg acctttcaaa tcaaggcttg cactatcttt caaaagaaaa
    31681 ggatacaaca ggtttctcaa gtcagtatgg ttgggttcac gcttttgcac atggagccga
    31741 tttactgaca gaggtggttt gtcatccaga ctttcctaaa aacagagttc atgaagtatt
    31801 tgatatactt ggccaactat ttaaaaggat gtcgattcgc tttacagatg atgaggattg
    31861 gcgtttagca agagtgatct atgaacctat tttataaggg aagttggagc aagaacaagt
    31921 agcttcttgg ataaaaactg ttgattttcc gatagaagaa agggaggatt tttacaaatt
    31981 ttccaacttt agatcctgtc tggtggaagt ctatgtccaa cttgaccaga gaaatagttt
    32041 acaagatgag ttgaaagaag ctatccagtc ttttcaatac tagagattag ctaatagttc
    32101 tatgattttc aaaaaatttc caatcaattt tcttgaaacc ctttcctact tttgatagac
    32161 tagtatctag tttttgaaaa aaggagaaag aaaatgaaaa aatttgttgc tgagttaatc
    32221 ggtacgttca tgcttgtgtt cgttgggaca ggagctgttg tttttggaaa tggtcttgat
    32281 ggccttggtc accttggaat cgcctttgcc tttggtttgg caatcgtggt ggcagcctac
    32341 tcaatcggaa ctgtttcagg tgctcacttg aacccggctg tttcgattgc tatgtttgta
    32401 aacaaacgtt tgtcatcttc agaacttgta aactacatcc ttggtcaggt tgttggagct
    32461 ttcatcgctt ctggcgcagt cttcttcctc ttggctaatt caggtatgtc aactgctagt
    32521 cttggtgaaa atgccttggc aaacggtgtc actgtctttg gtggtttctt gtttgaagtc
    32581 attgcaactt tcttgtttgt cttagttatt atgactgtga cttcagaaag taagggcaat
    32641 ggcgcgattg ctggtttggt aatcggtttg tcattgatgg cgatgattct tgtcggattg
    32701 aagattactg gactttcagt aaacccagct cgtagcttgg caccagctgt cttggtaggc
    32761 ggcgcagccc ttcaacaagt ttggattttc atccttgcac caatcgctgg tggagttctt
    32821 gcagcccttg ttgcaaaaaa tttccttgga acagaaaaat aattgaaact caaaaagcct
    32881 tgctcctcat cttgaggaac agggcttttt cgtatgatac tcttcgaaaa tctcttcaaa
    32941 ccacgtcagc tttaccttgc cgtaggtatg gttactgact acgtcagttc tatctgcaac
    33001 ctcaaaacag tgttttaagc tgacttcgtc agttctatct acaacctcaa aacagtgttt
    33061 taagctgact tcgtcagttc tatctgcaac ctcaaaacag tgttttgagc tgacttcgtc
    33121 agtcttatct ataacctcaa acactgcttt gagcaacctg cggctaactt cctagtttgc
    33181 tctttgattt tcattgagta tgactttagc ggttgtcaat tttctctgga taaaggtcgt
    33241 gttggaagag gcgttgttct gccaagtcct catacttagt tccttgctta ccgtagttgt
    33301 agtaggggtc gattgaaatg ccaccgcgcg gagtgaattt tccccagact tctaaatagc
    33361 gagggtctag caagttgacc aagtctttcc cgatggtgtt gatacagttt tcgtggaaat
    33421 ctccgtgatt tcggtagcta aatagatata gtttgaggga ttttgactcg acacagagct
    33481 tgtcaggaat gtaggaaata tgaatcgtcg caaagtctgg ctgagcagtg atttgtccca
    33541 gcagagacat atcgaggata tggtgacgaa tgccctgttc cttagcgatt tctctagcaa
    33601 tttgaatttc gaggtgatga cgttggccgt aggcaaaggt gacagcttcg actgtttcat
    33661 agtgttgcat aacccagaaa aggcaggttg ttgaatcttg accaccacta aagacgacca
    33721 aggctgattg acgtttcata gtactccttc caaaatggga aatgttcaga gcatgcaaaa
    33781 agctcctatt agggagctaa aaaataccaa atcgagtttt tttagcgatg gcatatccca
    33841 aacatcgtaa tattctactt atatagtaaa atgaaataag aacaggacaa atcgatcagg
    33901 acagttaaat cgatttctaa caatgtttta gaagtagagg tgtactattc tagtttcaat
    33961 ctactatagt ctagcatatt ttttgaaaaa tggcaaaggg caagaaaaaa gagaccaaag
    34021 aaagtacttg gtctctcgtt tgattagctc aattcagcaa tgatggcctt gatttgttct
    34081 gctgtgtgaa cacctgcaac ttgtttgaca acttggccgt cttttttgaa gagaagagtt
    34141 ggaatagaca tgattccaaa agcacgagct gtgtttggat tttcatcaac gtccatttta
    34201 acgattttca agacatcttc tgaaagttct tcagacaatt tgtccaagat tggaccttgc
    34261 atacgacatg gaccacacca agttgcccag aagtctacta agaccaaacc atcttttgtt
    34321 tcttgttcga atgttgcatc tgtaattgct tttgccattg tatttctcct ttttttagtt
    34381 atattggctt aaatcttgtt tcatgagata gaagaagata tctccataag tcccatggta
    34441 gtccaaatta tgacccttgt aagttaattt ttggacaggg tagtagtctg cgacgccgat
    34501 aaggcaagct tgttgcgaac gttcaaagtc ttcataagac tcgaaagtca cagttctttc
    34561 gttcttgctg gcatctatat aggtaatttc aatcatattt aaaactcctt tgtttaatgc
    34621 taactttatt ttactcctta taaaagagaa tgtcaagaaa aatgattgcg cacgcaactt
    34681 tttttaaaaa tcatcttaaa tcaagaaatc caaacctgct tccaagcttt cttcgacagt
    34741 cttttgtagc gaggccagtg tcttttgccc atcatttgtc aggcagataa aactagagcg
    34801 tctatcttga tggcaacaca tgcgactgag tagaccgcaa tttttagctt ccaagcgagc
    34861 caccatccta gaaactgcgc tcgggctcag atgaagttta tctggcaggt caatctggcg
    34921 tagagatttt tcttcagcca agtccagata gtagagcagg tagaactctt tcaaggtcag
    34981 actttgctcg ctctgttggg caatggtctc ttccaagaga ctttcaattt ctttctgacg
    35041 ccgattgaag tcaaaccatt tttccaaata ggtcatagtg tctcctttct ttttagagtc
    35101 ataaatagaa gaaagtccat taacgggcag tctctgcgtc acaagatgat tgcgcatgca
    35161 ataattatac tacttttcaa gaatgctggc aagctctgtt ttttagtggt tttatttttt
    35221 actgtctata tttttggtaa aaatcaactt ttacttggat gaaggttttg gcttcacgta
    35281 ggagttgaag aagggtggcg cgggtttcaa attcttctct tgtcttgggc agactgcggt
    35341 tccggaagac ttccagataa cgttcaattt catctagcaa atcagaagca ggattggtct
    35401 ggctcagttg acctgcaatt tttgaaaaga gttgcgctaa gatcaggctt tcactggcgg
    35461 caaggtgaca agtgttaatc tgttgggcca tgtttctcag gatacgactt tgtcgttgtc
    35521 tcatctcaaa gtagtggata tggtagtcgg tctggtgaaa gaggtggtca gagtgatcca
    35581 aatagaccag tctgagggct tctttcaaaa gcgtgtctaa ttctgctacc agctgtgctc
    35641 ggttgcgtcc gtctcctctg gataaatagt atttgaagcg ctggaggata tcttttaact
    35701 tttcttccac cagcgtgtgg tagtgctgga tttcctcttc tcgtgaaggc atatagagat
    35761 taacaagcaa ggcaaatcct gtaccaatag caaagagaag gaattcattg actagaaggt
    35821 ctggagaggt tgactcttga accaagagat ggctaaccaa aacagtgctt ggtgtgatgc
    35881 caatttccca gcccatcttg taggctaaag gaacgtagaa ggccagatag aggccgagac
    35941 tccagatatg aaatccgctc aagtgaaaag ctagaacacc gatagccaga gctagaagca
    36001 tagaaaaaag acgattgcga gccagtttta aagtacttct acgcgtatca gataggctca
    36061 agagagcgat aattccagcc gaaactgctg atgaaagatt gagaaaataa gcaagcaggc
    36121 aggcaagaca ggtagctaag atgagcttgg tcgtacgttg gctaatagac ataagaattt
    36181 cctaataagt tagaataaaa gcgtaaaaga caagacatga gcaggcttgc cttgatgagt
    36241 tattttttac gggttgctgc gtattcggca acggcggtaa agaggacatc tgtagaagag
    36301 ttaagggctg tttcacatga gtcttggatg acaccaatca caaaaccaac cccaacaact
    36361 tgtatggcaa tatcgttaga aataccgaaa aggctacaag caactgggat aagaaggagg
    36421 gaacctccgg caatacctga agcaccacag gctgagatag ctgctaccac actgaggaca
    36481 aaggctgtgg caaagtcaac aggaattcca agagtgttaa ctgcagcaag ggtcaaaacg
    36541 ttaatggtaa tcgctactcc agccatattg atagtagaac cgagtgggat agaaacagaa
    36601 taggtatctg ggttgagtcc aaggtcatgg cagagtttca tgttgacagg aatgttagcc
    36661 gcagaactac gagtgaaaaa ggctgtcaca ccgctgacac ggaggcagtt ccaaactaga
    36721 gggtaaggat tgcgtctcat aaagaagaag gcaatcaaag ggtgaccaca agggcaacaa
    36781 aaagcatagt cgttactaat agaaccaata aaataccgta gttggtaagg cttccgactc
    36841 ccttgtcaga aatggtttta aaaacaagac caaggcttcc aaatggagcc agattgatga
    36901 tccattcgac aattttagaa gtcacgtcag cgatagtttt tagcaattct ttactatttt
    36961 tactggcttc tctcatagcg attccaaaaa tgactgccca agataagatt ctaatatagt
    37021 tagcagtaaa cagggcgttg actgggctgt caaccagttt gagcaagagg ttgctgagaa
    37081 cctgcccaac cccatctggt ggtgcaattt cagtattggc actatttagg gtaatttcaa
    37141 tagggacgat gaaacttgct agtacagcta caagagcagc ggcgaaagtc cctatcatag
    37201 gatatacaag aaaacaacag ttttcatatt gctatcttgt cccttttgat gttggaaagg
    37261 gcattggcaa cgagggcaaa gactaggata ggagcaacag cttttagacc tccaacgaat
    37321 aaatccccga gtagcccaat ccctgagaga ttaggaaggg tcagtcctag gattccccac
    37381 aaagcatacc aatcaagata cgcttgacaa ggcttgcctt attccaagca tgaatgattc
    37441 ttttcataat aatctccttt ttgtgtagtg attatgatta tagtataaat gatagacaaa
    37501 atcaagaatt ttctgtctat tttttgaata tttatggaga atgagactga tgaaaatatg
    37561 gtataatgaa ataaaggagt tttatatgca aaaatttatt caggcttata ttgaaaagct
    37621 agatgtgaca accattatcg agaatattct aaccaaggtc atttctcttt tactgctttt
    37681 gattgtattt tatattgcta aaaaaatgct tcataccatg gtgcagagaa ttgtcaaacc
    37741 ttctctaaaa atgtctcgtc atgatgtcgg acgccaaaaa accatctcac gtttactaga
    37801 aaatgtgttt aattatacgc tatatttctt tttactctac tgcattttgt cgattttagg
    37861 tttgccagtt tctagtttgc tggctggagc tggtattgct ggggtagcga ttggtatggg
    37921 agcccaaggc tttctgtctg atgtcatcaa tggctttttc atcctctttg aacgtcaact
    37981 ggatgtggga gatgaggtcg ttctgacaaa tggaccgatt actgtatcgg gtaaggttgt
    38041 cagtgtggga attcgtacga cacagcttcg tagcgaggag caagcccttc actttgtccc
    38101 taaccgaaat atcacagttg ttagcaattt ctcacgcaca gactagacct gttattttaa
    38161 gtaatttgtg gtacaataga gggagtttaa taaggagaaa agatggtttt agaaaagcag
    38221 ttgggcaatg gttgtacctg gatagaccta gacctaggaa agttgaataa actagaagac
    38281 ctttctgaaa tttacggttt ggacaaggaa accattgaat acgcactgga tagaaacgag
    38341 cgcgcccaca tggactacca ccgtgaaagt gggacggtta cctttatcta taatgtccta
    38401 gacgtaaaaa aggacaaggc ctactatgag acttttccca tgacctttat tgtcgagcat
    38461 cgtcgcctga ttaccattag taataccaag aacgcctatg tcattgaaca gatgactcgt
    38521 tatctggaga gccatgacac gctttcgatt tataagtttc tctttgccag tctggaaatc
    38581 atcagcaatg cctactatcc tgtcattgag cagatggaca agagtaggga tgaggtcaat
    38641 gacctcttgc gccagcgaac taccaagaaa aacctctttg ccctgtctga tttggagact
    38701 ggtatggttt atctaacggc agctgccaaa caaaatcgga ttttgttaga gcatattcaa
    38761 ggtcatgcct tgtatcgtag ttttgatgag attgagagag aacagtttga tgatgccatg
    38821 attgaggctc atcagctggt atccatgaca gacctaatct ctcagatttt acagcagctt
    38881 tcagcctctt acaacaatat tctaaacaat aatctgaatg acaatttgac aactttgact
    38941 atcatttcag tcttgctagc tgttttggca gtcgtgacag gctttttcgg aatgaatgtt
    39001 cccttacctt taacagatga gccccatgct tggctctata tcagtttggc tagtgcaggt
    39061 ttgtggattg ttttatcctt gttactaagg aaaattgcga aaaaaagtta agaaaaggag
    39121 ccagaatggc gattgaaaat tatataccag attttgctgt ggaagcagtc tatgatctga
    39181 cagtcccaag cctgcaggcg cagggaatca aggctgtttt ggtcgatttg gataataccc
    39241 tcattgcttg gaacaaccct gatggaacgc cagagatgaa gcaatggcta catgaccttc
    39301 gggacgcggg tattggcatt atcgtagtgt caaataacac caaaaaacgc gttcaacgag
    39361 cagttgagaa atttgggatt gattacgttt actgggcctt gaagcccttc acatttggta
    39421 ttgaccgtgc tatgaaggaa ttccactatg acaaaaagga agtggtcatg gttggcgacc
    39481 agctcatgac agatatacga gcagcccacc gtgcagggat tcggtcaatt ttagtcaaac
    39541 ccttggtcca acatgactca atcaaaacgc agattaaccg aactcgtgag cgtcgtgtta
    39601 tgagaaaaat cactgaaaag tacggaccga ttacatataa aaaaggaatt taactatgga
    39661 agaaattctc tgtattggtt gtggagcaac cattcagacg acagataaag ctggtcttgg
    39721 ttttaccccc cagtcggcac ttgaaaaagg tttggagact ggcgaagtct attgccaacg
    39781 ctgtttccgt ctccgccact acaatgaaat cacagatgtc cagttgacga acgatgattt
    39841 cctcaagctc ttgcacgagg tgggagacag tgatgcctta gtggtcaatg tcattgatat
    39901 ctttgatttt aatggatctg tcatcccagg tttaccacgt ttcgtctcgg gcaatgatgt
    39961 cctcttggta ggaaataaaa aagatatcct tcctaagtca gttaagtctg gtaagattag
    40021 ccagtggctc atgaaacgtg cccatgaaga aggtcttcgt ccagtcgatg tggtcctaac
    40081 ttcagcacaa aataaacatg ccattaagga agtcattgac aagattgaac actaccgtaa
    40141 gggccgcgat gtctatgtgg tcggtgtgac caacgttgga aaatcaactc taatcaatgc
    40201 tattatccaa gaaatcacgg gtgatcagaa tgtcatcact acttcacgct tcccaggtac
    40261 aaccttggac aaaatagaga ttccgcttga cgacggatct tatatttacg atacgccggg
    40321 aattatccac cgccaccaga tggctcacta cttgacggcc aaaaacctca agtatgtcag
    40381 tcctaaaaag gaaatcaagc ctaagaccta tcagcttaat cctgagcaaa ccctattttt
    40441 aggtggtttg ggacgctttg actttatagc aggagaaaag caaggattta ctgctttctt
    40501 tgataatgaa ctcaaactcc atcgtagcaa gcttgaagga gctagtgctt tctacgataa
    40561 gcacctggga actcttctga caccaccaaa tagcaaggaa aaagaagatt tcccaaggct
    40621 agtccagcat gtctttacca ttaaagataa gacagaccta gtcatctcag gcctaggctg
    40681 gattcgtgta acaggcatag caaaagtcgc cgtctgggca ccagaaggcg tcgccgtcgt
    40741 cacacgaaaa gcaattattt aaaacaaaat cgctgagcga acaaagtgag ctcatatagc
    40801 gatagttatt gccgtggtgt gattgccaat ctgtagattg gcaaggggca caattgagac
    40861 caaggctcaa ttgtgaggtc aggaaatcca tttttcaaag atgaaatctt tggaaaatta
    40921 gttccgaccg tccctcacca cctaaaataa ctatcaaaaa acaaggaaga aaattatgtc
    40981 attaacatca aaacaacgtg ccttcctcaa cagccaggca cacaccctca aacctatcat
    41041 ccaaatcggg aaaaatggac tcaacgacca aatcaaaacc agcgtccgtc aagctcttga
    41101 tgcgcgtgaa ttaatcaagg ttactctctt acaaaacaca gatgaaaaca tccacgaagt
    41161 agctgaaatt ttggaagaag aaatcggtgt ggatacagtc caaaaaatag gacgcatctt
    41221 gattttgttt aagcaatcta gcaagaaaga aaatcgcaag atttctaaga aagtcaaaga
    41281 aatctaagac cgaaactcca aataactgtt tttatagaga aataaagggg actagcctat
    41341 gacaatcgaa ctattgactc cctttaccaa ggtagagttg gagccagaaa tcaaggagaa
    41401 aaaacgcaaa caagttggga ttttaggggg gaattttaac cctgttcaca atgcccatct
    41461 cattgttgcg gatcaagtac ggcaacagtt gggactggat caagttcttc tcatgcctga
    41521 ataccaacct cctcacgttg ataaaaagga aaccatccct gaacaccatc gtctcaagat
    41581 gcttgagttg gcaattgagg gaattgacgg cctagtcatt gaaaccattg agttggagcg
    41641 caagggtatt tcctacacct acgacaccat gaagattttg acagagaaga atccagatac
    41701 ggattattac tttatcatcg gtgccgacat ggttgactat ctgcctaagt ggtaccgaat
    41761 tgatgaactg gttgacatgg ttcagtttgt gggggttcag cgtccacgct acaaggtagg
    41821 gacttcctat ccagttatct gggtggacgt accgctcatg gatatctcgt ccagcatggt
    41881 gcgggacttc cttgcccaag gtcggaaacc caactttctc ctacctcagc cagtgctaga
    41941 ctacatcgag aaggaggggc tctactgatg tcctatcaag actatatcaa ctgctcccgt
    42001 gaggccttgt tggaaaaaat ggcagagttt ctacctgaga aacgtctaac ccattgtcta
    42061 ggtgtggagc gtgccgctat ggaattagct cagcgctttg gtgtagatgt tgagaaagca
    42121 agtctagcag gtcttcttca tgactatgct aaaaagttgt caaatcagga atttctagcc
    42181 ttgattgacc gttaccagct agaccctgac ctcaaaaact ggggcaataa tgtctggcat
    42241 ggtatggtcg gaatttacaa aattcaggaa gatttggatt tgcatgattc agaaatcctg
    42301 cgagccattg aagtccatac agtcggtgct ggtcaaatga cagacctaga taaggtcatc
    42361 tacgtcgcag actatatcga gcacaatcga gcctttcctg gagtagatgt ggcgcgtgag
    42421 attgcaaatc tatcgctcaa taaggcggtg gcctacgaaa cagctcgtac cgtggagtat
    42481 ctagctcatc agggattccc catctatccc caaacccttg aaacctataa cgcctttgtg
    42541 cactatttga aagagaacta aatgaagacg gcttttataa tcattgatgt tcagaatgtt
    42601 ttagtagaaa ctgggttcca gacaaaaagt ctattgggaa aaatttctta tttacaaaac
    42661 caggctagaa gcaagaatat tgaaattatc tatgttcaac atattgagaa ctctgaagct
    42721 caaacatcag aagattggca gttatctgcg cttttaaatc gaaaacctgc tgaaaaggtc
    42781 tttcagaaga agtataacag tattttcaaa gaaactggct taaaagaata cttggataag
    42841 caggggattg aaaaattagt tttatgtggt atgcagacag aatattgtgt ggatacctct
    42901 gtcaaggttg cctttgaata tggctatcag cttattgttc cagaaggtgc tgtcacaacc
    42961 tttgatgggg atgacattcc agcagaaacg attaatgaat tttatgagga catttgggag
    43021 gagcgctttg cagatgttct agattacaaa catattttct aaaaagagga ttaaatgaac
    43081 gaaaaagaat tactagaact agtcgtgaaa gcggctgatg agaaacgtgc ggaggatatc
    43141 cttgcacttg atgtacaaga tttgactagt gtgacggact actttgtcat cactagctca
    43201 atgaatagcc gtcagttgga cgctatcgca gctaatatcc gtgaaaaagt agctcaagcg
    43261 ggctttaaag gtagccatgt cgaaggcgat gcagctggag gctgggtctt actggacctc
    43321 ggtgctgttg tcgtgcatat cttttcagag gaaatgcgtg cccattataa tctagagaag
    43381 ctatggcatg aggcgaattc agtagatatt tcagaagctc ttgcttagaa gatgaactca
    43441 gttgtagtca actgggtttc tttgcttatt ttagaaaaat tgatagaaag gtaaagggcc
    43501 tcgtgtttgt ttcatttcga aactgaacac gagctaaaag ctgagataaa aagtaacttt
    43561 ctttgtatct gacgataggg aagaaagttt cctatgtact ctttgctttt aaggctcttt
    43621 gtatcttaga aaggatttga acccgtcctg taattatcgg aaaatagata gccttccttg
    43681 gagctcggct ccatcgtaag gctcctaatt ttctatcgaa ttacgggcgg acttggtatc
    43741 atgttttatg gcgacttatg aaacctttgc ggctgtctat gatgcggtca tggacgatag
    43801 tttatacgac aaatggacga atttttctct gcgtcatttg cctaagacca aggagagaaa
    43861 gaaactcttg gaactggctt gtgggacagg aattcaatca gtgcgcttct ctcaggctgg
    43921 ttttgatgtg actggacttg acttgagtgc ggatatgttg aagattgcgg agaagagagc
    43981 aacttcagcc aagcaaaaga ttgcttttat agaaggtaat atgctgaatt tgtccaaggc
    44041 agggaaatac gattttgtca cgtgttattc ggactctatc tgctatatgc aggatgaggt
    44101 ggaagtaggg gacgtcttta aggacgtgta caatgcgctg aatgaagagg gagttttcat
    44161 ctttgacgtg cactcgacct accagacaga tgaagtattc cctggctatt cctaccatga
    44221 aaatgcggaa gattttgcca tgctttggga tacatatgag gacgaaactc ctcactccat
    44281 cgtgcatgag ctgactttct ttatcaagga ggctgacggt tcctttagtc gccacgatga
    44341 agtacatgag gagaggacct atgagatctt gacctatgat atcttgctgg aacaggctgg
    44401 atttaagtcc ttcaaactct atgcagactt tgaggataag gagccaacag aaactagcac
    44461 ccgttggttt tttgtggcgc agaagtaaat caaatattgt taatcttatg cttaggaggt
    44521 aagggaaaat gaatatacca ataccatttg gtgatattct tgaaaaagaa gtaattacca
    44581 atatacctaa aatttatcaa aagttaaagc aaatttataa cgacttacag tt
//
LOCUS       DAVLIK010000014        44292 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLIK010000014 DAVLIK010000000
VERSION     DAVLIK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.014"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            87..449
                     /locus_tag="VXE87_000817"
     CDS             87..449
                     /locus_tag="VXE87_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842393.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNTLKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            985..1677
                     /locus_tag="VXE87_000818"
     CDS             985..1677
                     /locus_tag="VXE87_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0842394.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1730..4141
                     /locus_tag="VXE87_000819"
     CDS             1730..4141
                     /locus_tag="VXE87_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0842395.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRYCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4391..5092
                     /locus_tag="VXE87_000820"
     CDS             4391..5092
                     /locus_tag="VXE87_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842396.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5094..7802
                     /locus_tag="VXE87_000821"
     CDS             5094..7802
                     /locus_tag="VXE87_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0842397.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEN
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7898..8389)
                     /gene="tpx"
                     /locus_tag="VXE87_000822"
     CDS             complement(7898..8389)
                     /gene="tpx"
                     /locus_tag="VXE87_000822"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0842398.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8512..9441)
                     /gene="psaA"
                     /locus_tag="VXE87_000823"
     CDS             complement(8512..9441)
                     /gene="psaA"
                     /locus_tag="VXE87_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0842399.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9473..10321)
                     /locus_tag="VXE87_000824"
     CDS             complement(9473..10321)
                     /locus_tag="VXE87_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0842400.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10318..11040)
                     /locus_tag="VXE87_000825"
     CDS             complement(10318..11040)
                     /locus_tag="VXE87_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0842401.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11331..13223
                     /gene="pepO"
                     /locus_tag="VXE87_000826"
     CDS             11331..13223
                     /gene="pepO"
                     /locus_tag="VXE87_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0842402.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEERSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13346..13975)
                     /locus_tag="VXE87_000827"
     CDS             complement(13346..13975)
                     /locus_tag="VXE87_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0842403.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAYLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14932..17154
                     /locus_tag="VXE87_000828"
     CDS             14932..17154
                     /locus_tag="VXE87_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0842404.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17184..17627
                     /locus_tag="VXE87_000829"
     CDS             17184..17627
                     /locus_tag="VXE87_000829"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0842405.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(17864..18079)
                     /locus_tag="VXE87_000830"
     CDS             complement(17864..18079)
                     /locus_tag="VXE87_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842406.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFSQLYSQIRPRF"
     gene            complement(18243..18893)
                     /locus_tag="VXE87_000831"
     CDS             complement(18243..18893)
                     /locus_tag="VXE87_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0842407.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            19005..19847
                     /locus_tag="VXE87_000832"
     CDS             19005..19847
                     /locus_tag="VXE87_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0842408.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            19923..20360
                     /locus_tag="VXE87_000833"
     CDS             19923..20360
                     /locus_tag="VXE87_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0842409.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRN
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            20428..20679
                     /locus_tag="VXE87_000834"
     CDS             20428..20679
                     /locus_tag="VXE87_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842410.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLK"
     gene            complement(20821..21894)
                     /locus_tag="VXE87_000835"
     CDS             complement(20821..21894)
                     /locus_tag="VXE87_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0842411.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLELAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            22050..22727
                     /locus_tag="VXE87_000836"
     CDS             22050..22727
                     /locus_tag="VXE87_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0842412.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            22720..23694
                     /locus_tag="VXE87_000837"
     CDS             22720..23694
                     /locus_tag="VXE87_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0842413.1"
                     /translation="MLDWKQFFLAYLRSRSRLFVYLLSLAFLVLLFQFLFASLGIYFL
                     YFFLLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(23743..25686)
                     /gene="thrS"
                     /locus_tag="VXE87_000838"
     CDS             complement(23743..25686)
                     /gene="thrS"
                     /locus_tag="VXE87_000838"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0842414.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(25744..25920)
                     /locus_tag="VXE87_000839"
     CDS             complement(25744..25920)
                     /locus_tag="VXE87_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0842415.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMKNF
                     LSDKEKQLNVRTRK"
     gene            complement(25927..26067)
                     /locus_tag="VXE87_000840"
     CDS             complement(25927..26067)
                     /locus_tag="VXE87_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0842416.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(26498..26698)
                     /locus_tag="VXE87_000841"
     CDS             complement(26498..26698)
                     /locus_tag="VXE87_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842417.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIISLLYSYRFRFSL"
     gene            26937..27566
                     /locus_tag="VXE87_000842"
     CDS             26937..27566
                     /locus_tag="VXE87_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0842418.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            27707..27976
                     /gene="rpsO"
                     /locus_tag="VXE87_000843"
     CDS             27707..27976
                     /gene="rpsO"
                     /locus_tag="VXE87_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0842419.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            28790..29404
                     /locus_tag="VXE87_000844"
     CDS             28790..29404
                     /locus_tag="VXE87_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0842420.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(29696..30445)
                     /locus_tag="VXE87_000845"
     CDS             complement(29696..30445)
                     /locus_tag="VXE87_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0842421.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTNKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            30578..32914
                     /locus_tag="VXE87_000846"
     CDS             30578..32914
                     /locus_tag="VXE87_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0842422.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFGVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFSRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            33016..33693
                     /locus_tag="VXE87_000847"
     CDS             33016..33693
                     /locus_tag="VXE87_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0842423.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGCLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQNHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            33680..34477
                     /locus_tag="VXE87_000848"
     CDS             33680..34477
                     /locus_tag="VXE87_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0842424.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            34494..35597
                     /locus_tag="VXE87_000849"
     CDS             34494..35597
                     /locus_tag="VXE87_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0842425.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            35604..35750
                     /locus_tag="VXE87_000850"
     CDS             35604..35750
                     /locus_tag="VXE87_000850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842426.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVYRTDEVSNHTHGKETLTWFELD
                     FRRV"
     gene            35853..36872
                     /gene="galE"
                     /locus_tag="VXE87_000851"
     CDS             35853..36872
                     /gene="galE"
                     /locus_tag="VXE87_000851"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0842427.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            36874..37827
                     /locus_tag="VXE87_000852"
     CDS             36874..37827
                     /locus_tag="VXE87_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0842428.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(37889..38095)
                     /locus_tag="VXE87_000853"
     CDS             complement(37889..38095)
                     /locus_tag="VXE87_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0842429.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSRDVLEAVKNCPTRALIGNQEA"
     gene            38147..38623
                     /locus_tag="VXE87_000854"
     CDS             38147..38623
                     /locus_tag="VXE87_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0842430.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            38632..39303
                     /locus_tag="VXE87_000855"
     CDS             38632..39303
                     /locus_tag="VXE87_000855"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0842431.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            39434..39772
                     /locus_tag="VXE87_000856"
     CDS             39434..39772
                     /locus_tag="VXE87_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0842432.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDIVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            39775..40404
                     /locus_tag="VXE87_000857"
     CDS             39775..40404
                     /locus_tag="VXE87_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0842433.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            40644..41795
                     /locus_tag="VXE87_000858"
     CDS             40644..41795
                     /locus_tag="VXE87_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0842434.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKKASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            42108..42857
                     /gene="truA"
                     /locus_tag="VXE87_000859"
     CDS             42108..42857
                     /gene="truA"
                     /locus_tag="VXE87_000859"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0842435.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            42847..43620
                     /locus_tag="VXE87_000860"
     CDS             42847..43620
                     /locus_tag="VXE87_000860"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0842436.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            43598..44059
                     /locus_tag="VXE87_000861"
     CDS             43598..44059
                     /locus_tag="VXE87_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0842437.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKFPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        12740 a         8315 c        10174 g        13063 t
ORIGIN      
        1 tattttataa tatcagaaaa tacttttttt aaaaagcaaa tatgatataa ttttatttga
       61 aaaaaaataa aaaaggagat tttattatga aatcaagtgg tatcgtcggt cttgtgggag
      121 gaattttact tcttatttgt ccttttgtct tgttgggaac agcggtaaat acagctgcta
      181 caactcttaa tggaggagct actgcagggg ctttttcagg tgttgcctta ctcttgaata
      241 ccttgaagat tgcaaatctt gttcttggta tcattgctat tgtttactat aaaggagata
      301 agcatgtagg tgcagctccg tctgtactaa tgattgtttc tggtgaagtt agtctcattc
      361 cattcttagg atgggttggg gggattcttg ctattatcgg aggatctcta ttccttgcaa
      421 cattgaagaa attcaaatca gaagaataaa aggtatttta gcatgaaaag aacaaaaaag
      481 tttatcggta taggagtagc tctattatct ctttctcttc tagttgcatg tggaacataa
      541 agttcaaaga atacttcaac aagtaatgat gagaagacag tagcaacatc caatagttca
      601 aaagaaacaa tcactttcga tacaccggtt gtaacagacg atgcgattga atcaatacgc
      661 acttatgcag attatataga tctttataaa aatatttttg atgattattt tactaaagct
      721 gaggaaggtt tcaaaggcac agctatggaa aataatgact cgtttactaa actaaaagag
      781 tcaactcaaa aattattcga tgcgcagaaa aaaaggttaa ataaatgaag atagaataga
      841 aacaaccaaa aacaatgtga ttgccaaaca ttgtcaaaca gtcctttcct ttttggtttt
      901 gactagcttt tttgtgaaaa attgtgtaaa atagaataga taaacgaggg gaaacctcgg
      961 aaaatttaaa ggagaatcca tctaatggta aaattggttt ttgctcgcca cggtgagtct
     1021 gaatggaaca aagctaacct tttcactggt tgggctgatg ttgatttgtc tgaaaaaggt
     1081 acacaacaag cgattgacgc tggtaaattg atcaaagaag ctggtatcga atttgaccaa
     1141 gcttacactt cagtattgaa acgtgctatc aaaacaacta acttggctct cgaagcttct
     1201 gaccaattgt gggttccagt tgaaaaatca tggcgcttga acgaacgtca ctacggtggt
     1261 ttgactggta aaaacaaagc tgaagctgct gaacaatttg gtgatgagca agttcacatc
     1321 tggcgtcgtt catacgatgt attgcctcca aacatggacc gtgatgatga gcactcagct
     1381 cacacagacc gtcgttacgc ttcacttgac gactcagtta tcccagatgc tgaaaacttg
     1441 aaagtgactt tggaacgtgc tcttccattc tgggaagata aaatcgctcc agctcttaaa
     1501 gatggtaaaa acgtattcgt aggagctcac ggtaactcaa tccgtgccct tgtaaaacac
     1561 atcaaaggtt tgtcagatga cgagatcatg gacgtggaaa tccctaactt cccaccattg
     1621 gtattcgaat tcgacgaaaa attgaacgtc gtttctgaat actaccttgg aaaataaaaa
     1681 attgtaagtc tagaattgat ttctaggctt tttatgttag tatggaagta tgataaggaa
     1741 taaaaaacaa gattatgtac tggcctacaa gcaaccagct tcaaccactt acatgggttg
     1801 ggaggaagaa gctttaccga taggcaatgg ttctttagga gcaaaagtat ttggccttat
     1861 aggggctgaa cggattcaat ttaatgaaaa aagtctctgg tctggaggtc cacttcctga
     1921 tagttcagat tatcagggtg gaaatcttca ggatcagtat gtttttttag ctgagattcg
     1981 gcaggctttg gagaagagag attacaatct ggctaaggaa ctggctgagc agcacctaat
     2041 tgggccaaaa acgagtcaat atgggaccta tctgtctttt ggggatattc acattgagtt
     2101 cagccagcaa ggtacgactt tgtctcaggt gacggactat cagagacagt tgaatattag
     2161 taaggcactt gcgacgactt cttatgtcta taagggaacg cgatttgaac gtgaagcttt
     2221 tgcgagtttt ccagatgatc tcttggttca atgttttact aaggaagggt tggaaactct
     2281 agattttact atagaactat ccttgacctg tgatttggct tctaatggaa agtatgagca
     2341 ggaaaaatct gattacaagg agtgtaagtt ggatattact gattctcata tcttgatgaa
     2401 gggaagagtt aaggataatg atctgcggtt tgctagttat ctagcttggg aaacggatgg
     2461 agatattaga gtttggtcag atagggttca gatatcagga gccagttatg ccaatctctt
     2521 cttggccgct aagacggatt ttgcccaaaa tcctgctagc aattatcgca agaaactaga
     2581 tttagagcaa caggtgatag acttggtgga cacagctaaa gaaaagggct atacccaatt
     2641 gaaatcaagg catatcgagg actaccaagc cttattccag cgtgttcaat tggatttgga
     2701 agctgatgtt gacgcatcca ctacagatga tttgttaaaa aattataagc cacaagaagg
     2761 gcaggctttg gaggagctgt tcttccagta tggacggtat ttattgatta gttcgtccag
     2821 atactgccca gatgctctac cagctaacct acagggagtc tggaatgcgg tcgacaatcc
     2881 tccttggaat tcggactatc acttaaatgt caatctgcag atgaattatt ggccagccta
     2941 tgttaccaat cttctagaga cggtctttcc agtcatcaat tatgtagatg atttgcgtgt
     3001 ctatggtcgt ctagcggctg taaagtatgc aggaatcgtc tctcagaaag gtgaggagaa
     3061 tggttggttg gttcatactc aagcgactcc ctttggttgg acggcacctg gttgggatta
     3121 ctattggggt tggtcaccag ctgccaacgc gtggatgatg caaaccgttt atgaagccta
     3181 ttcattttat agggaccaag actatctcag ggagaaaatt tatcccatgt tgagggaaac
     3241 ggttcgtttt tggaatgcct ttttacataa ggatcagcag gcgcagcgtt gggtgtcttc
     3301 tccgtcttat tccccagaac atgggccgat ttcgattggc aatacctatg accaatctct
     3361 gatttggcag ttatttcatg attttattca ggctgctcag gaattgggac tggatgagga
     3421 cttgttgact gaggttaagg agaagtctga tttactaaat cctttgcaaa tcactcaatc
     3481 tggtcgaatc agggagtggt atgaggagga agagcagtat tttcaaaatg agaaagtgga
     3541 ggcccagcat cggcacgctt cccatctagt gggactctat cctggcaatc tctttagcta
     3601 caagggacaa gagtatattg aagcggcgcg tgctagcctc aatgatcgtg gagatggcgg
     3661 cacaggctgg tccaaggcta ataagatcaa tctctgggcg cgtttgggag atggtaatcg
     3721 agcccataaa ttattggcag agcagttaaa gacatccacc ttgccaaatc tttggtgtag
     3781 ccatcctcct tttcagatag atggtaattt tggtgctact agtggcatgg cagaaatgtt
     3841 actccagtct catgcagctt atctggtacc tctagctgcc ttacctgatg cttggtcaac
     3901 aggttctgtt tcaggcttaa tggcacgtgg acattttgaa gtgagcatga gctgggaaga
     3961 taaaaaactc ttacagttga ccattttatc aaggagtgga ggagatttgc gagtttctta
     4021 tccagatatt gagaagagtg tgattaaaat gaatcaagaa aaaataaaag cgaaatgcat
     4081 ggggaaagat tgtatttcgg tggcaacagc agaaggtgat cttgttcaat tttattttta
     4141 agaagatgtt ataaggcagt aatttgaaac tgccttttaa taaggattta agaatgtaag
     4201 cagtttccaa ctagttgaaa aagcgttata atgataatag gaagtaatac tcaatgaaaa
     4261 tcaaagagca caaactagga agctagccgc aggttgctca aaacagtgtt ttgaggttgc
     4321 agatggaagc tgacgtggtt tgaagagaga ttttcgagga gtataatttg tttgatagag
     4381 ggtgggtctg atggcttata ttgagatgaa acactgttac aagcgttatc aggttgggga
     4441 cacggagatt gtggccaatc gtgatgtgaa ttttgagatt gaaaaggggg agctggttat
     4501 tatccttggt gcttcaggtg caggtaagtc aacagttctt aaccttcttg ggggaatgga
     4561 taccaatgat gaaggggaaa tctggattga tggtgttaat attgcggatt atagttccca
     4621 ccagcgcacc aattaccgta gaaatgatgt ggggtttgtt tttcagtttt ataatctagt
     4681 ttctaatctg acagctaagg aaaatgtgga attggcttct gaaattgtga cagatgcctt
     4741 gaatcctgat caggtcttga cagatgtagg tctggctcat cgtctcaata actttccagc
     4801 ccagctttct ggaggggagc aacagcgagt ctccattgca cgcgcggtag ccaaaaatcc
     4861 taaaattctt ctttgtgatg aacctactgg agccttggat tatcagacgg gcaagcaggt
     4921 tttgaaaatt ctccaagata tgtctcgtca aaagggagcg acggtgatca tcgtgactca
     4981 taatggagct ttggcgccca ttgctgatcg cgtgattcat atgcacgatg ccagtgtcaa
     5041 ggatgtggtg ctcaaccagc atcctcagga tattgacagt ttggagtact agtatgatca
     5101 agcgaaaaac ttattggaag gacttaattc agtccttcac aggctccaag gggcgttttt
     5161 tatccatctt gatcctgatg atgttgggat ctctagcctt agtaggcctc aaagtaacca
     5221 gtcccaacat ggaggcgaca gctaatgctt atttaacaac tgctcaaacc ttggatttgg
     5281 cagtcatgtc taactatggc ttggatcaag cagaccaaga agaactaaaa cagacggagg
     5341 gcgcagaggt cgagtttggc tatttgacag atgtgactat ggataatggg caggatgcca
     5401 ttcggctgta ctccaaacca gagcgaattt caacctttca gctaagaaag ggacgacttc
     5461 ctcagtcaga caaggaaatc gctttggcca ctcatttgca aggccaatac agcgtgggac
     5521 aggagattag ttttaaagaa aaagaagagg gtcattcctc tttaaaagac catacttata
     5581 ccattactgg ttttgtggat tcggctgaaa tcctctccca gcgagatatg ggctacgcag
     5641 gaagtggaag tgggactctg acagcctatg gggtgatttt acctagtcag tttgatcaga
     5701 aagtctacaa tatagctcgt ttgaaatatc aagatttagc aggtttaaat gccttttcat
     5761 cagcttatga agaaaaatcc aagcaacatc aggaagagct tgaacaaatt ttatcagata
     5821 atggcaaggt acgtctgcaa cttttgaaaa aagaaggaca agagtctcta gacaaggggc
     5881 aagagaccct tgacaaggct cagactaatt tgcaggaagg caagcgtcgt ttagcagctg
     5941 ctcaagctcg tatacaggct caagaaagtc aactagcctt gtttcctcaa gttcagagag
     6001 agcaggctag tgctcaactt acccaagcca agcaggaatt gggcaaggaa gaggccaaac
     6061 taaagcaagc tgaacaaaat ctagcccaag aaaatgaaaa attagaaaaa catcagcaag
     6121 tcttggacga tttggcggag ccaaggtatc aggtctataa tcgtcagacc atgccaggtg
     6181 gtcagggcta tcttatgtat agcaatgctt catccagtat tcgagcagtg ggcaatatct
     6241 ttcctgtggt actttatgcc gtagcagcca tggtgacctt tacgaccatg actcgctttg
     6301 tagacgaaga gcgaactcat gcagggattt ttaaggcctt gggttatcgt agtaaggata
     6361 ttatcgccaa gtttctcctt tatggactag tagctgggac tgtcggaacg gctctaggta
     6421 gtatacttgg tcattatttg ctagccagtg taatttcaag tgtcattaca aaaggcatgg
     6481 tggtgggaga aactcagatt cagttctatt ggacctatag cttactagct cttgtcttga
     6541 gcttgttggc gagtgtgtta ccagcctatc tggtggcttg gagggaactt catgacgaag
     6601 cagcccagct tctacttcct aaacctcctg tcaaaggagc taaaatctta ttggagcgta
     6661 tcggttttat ctggcgtcgt ctcagtttta ctcataaggt aacagcccgc aacatctttc
     6721 gttataagca gagaatgttg atgacaatct ttggtgtggc aggttctgta gctctgctct
     6781 ttgcaggttt gggaatccaa tcttctgtag caggagttcc gtctaaacag tttcaacaaa
     6841 tccaacagta tcagatgctt gtctctgaaa atcctagtgc gaccaatcag gacaaggtag
     6901 agctagcaga agtgttgaaa gggcaggaga tactagccta ccagaaaatc tattctaaaa
     6961 cgctagacaa ggatttcaaa ggcaaggctg gtcttcaaaa cattactctt atgatgatag
     7021 agaaggaaga tttgactccc tttatccatc ttcaacatca tcagcaggag ctgacattaa
     7081 aagatggcat cgttattaca gctaaactcg cccagctggc aggtgtcaag gttgggcaga
     7141 ctttagaaat tgaaggtaag gaactaaagg tcgctgctat tactgagaac tacgttggtc
     7201 actttattta tatgagtcag gctagctatg agcaacttta cggacagcta ccccaagcca
     7261 acacttatct ggtctcatta agggatacca gtgcaactag tatcgaaagt caggcgggct
     7321 tgcttatgaa tcaatctgcg gtgtccagcg ttgtccaaaa tgcttcagcc attcgactct
     7381 tcgactctat cgctagctca ctcaatcaga ccatgaccat cttggtcatc gtatctgttc
     7441 tattagctat tgtcatcctt tacaatctga ccaatatcaa cgtagctgag agaatccgtg
     7501 aactctccac tatcaaggtt ctcggttttc ataataatga agtcacactc tacatttacc
     7561 gtgagacgat tgtgctgtcc cttgtgggaa tcgtacttgg tctgatagct ggtttctatt
     7621 tacaccaatt tttgattcaa atgatttcgc ctgcgactat tctcttttat ccgcaggtag
     7681 gctgggaagt ctatgtaatc ccagtggcag cagtaagcat cattttgacc ttgcttggtt
     7741 tcttcgtcaa ttattatctg agaaaggttg atatgttaga agctctgaaa tctgtagagt
     7801 aaggtagtta tttttagctg attgaacttc tatttactaa tattcaaaaa tcctccgttt
     7861 caaagagcag ggaactcttt gtgacagagg attttttcta tagggcttta gcagctgcaa
     7921 ttgcggcttc gaagtttggc tcagaattga tattatccac gtattcaacg tagcgaatcg
     7981 tattgtcagt atcgaggaca aagactgcgc gtgctaatag gtgccattcg ttgattaaga
     8041 gggcataatc gtgcccgaaa gaatggtcaa agtagtctga aagcataatg gcattgtcaa
     8101 ggccttcagc accgcaccaa cgtttttgag caaaaggtag gtccattgaa acagtcaata
     8161 cgaccgtgtt gtccagtcca gccaattctt cattaaaacg acgtgtttga gttgagcaga
     8221 tgcctgtatc gatagaagga acgacactca agactttttt cttgccatca aaatcagcca
     8281 gagatttttt agaaagatct gttgtagtaa gagaaaaatc aagcgccttg tcgccaactt
     8341 gtagttgttt acctgtaaag ctcacaggat ttccgagaaa agttaccata ggatactcca
     8401 atcttttttc ttccattgta tctgaaacag tcagaatttt ccaatgattt gaccggaaat
     8461 gtgggcatag aaaaaacgcc agctcacatg agaatgacgt ttttcagagg cttattttgc
     8521 caatccttca gcaatcttgt caaggttgta tttcatcatg ctgtagtagc tgtcgccttc
     8581 tttaccttgt tctgcgatag agtcagtaaa gatttgtgcg tagattggga tgtttgtgtc
     8641 ttgagaaaca gttttcattg gacggtcatc cacacttgat tctacaaaga gtgatggaac
     8701 ttttgtttgg cgaagttttt caaccaaggt cttgatttgt tcaggagttc cttcttcttc
     8761 agtattgatt tcccagatgt aggcacttgg gacaccatag gctttagaga agtatttgaa
     8821 tgctccttcg ctggttacaa tgagtttctt ttcagcaggg atcttattaa atttatcctt
     8881 actttcttta tcaagtttgt ctaacttatc agtatattct ttgagatttt tttcatagaa
     8941 ttctttattg ttagggtctt tggcgctcaa ttgtttggcg atatttttag caaaaataat
     9001 accgttttca aggttaagcc aagcgtgtgg gtcttctttt cctttttcat tttgaccttc
     9061 aaggtagata acatcaacgc cgtcgctgac tgcgaagtag tctttgtttt cagttttctt
     9121 ggcattttct accaattttg taaaccaagc attgccacct gtttcaaggt tgataccgtt
     9181 atagaaaatc aaatcagcct cagaagtttt cttaacgtct tcaggaagtg gttcgtattc
     9241 gtgtgggtct tgcccaatcg gaacgatact atgaaggtca attttgtcac cagcaatatt
     9301 tttagtaata tcagcgatga ttgagtttgt agcaacaact tttagttttt gaccagaagt
     9361 tgtatctttt tttccgctag cacatgctac aagaatgatt gcagaaagaa agagaacgag
     9421 taatgtacct aattttttca ttagatcctc caatttatta gggctttgcc ccttatttta
     9481 acaaatgttt atttttcagt ttcaaatatc gttgtttggg agcgataaag aagctaatga
     9541 gaaagaaact agcagctgta agcacgatac tagaacctgc cgcaacatta aaactatagc
     9601 caataaagag tcccaaaact gaagcagtag ctccgaaggt tgaggaaagg aaaatcatac
     9661 ttttcagact attagcatac agataagcag ttgcagctgg ggtaatcagc atggctacaa
     9721 tcaggatagt tccgacactt tgcatggctg tcacagacac gagagtcagg agtaccatga
     9781 gaaggtagtg atagaaattg acaggcattc ccatggcttt agccaagagt tcatcaaagg
     9841 aagttatcaa gagttgcttg aagaaaatcc aaattaacaa gaggatggct gcccccacac
     9901 ccatagtaat aaacatatcc gtatcttgga cggccaggat attaccaaaa aggatatgga
     9961 aaaggtcagt tgaactttta gcgacaccaa tcaagatgat accgagggct aagaaagaag
    10021 aaaaggtaat gccgatggcg gtatcgcttt tgataatcga gtttcctttg atgtaggtaa
    10081 tgatgatggc agctagcaat ccaaagacaa tggctccgat aaagaagtca aggcccaaga
    10141 tgaaggagag ggctacacct ggtaagacag catgtgaaat ggcatctccc atgagtgaca
    10201 tcccgcgtag aataatgaaa catcccacgg ctccagctac aatcccgacg acaatagctg
    10261 ttatcaaggc attttgtagg aaatggaatt tttgcaatcc atcgataaat tctgcaatca
    10321 taggtcacct ccattgaaaa agagttgatt accgtaagct tcttttagat tggtttcggt
    10381 aaaagtttct tttgttggac caaaggcaat cacttctcga ttgacaagta agacttgatc
    10441 gaagtagtgg ggaatcttgc tgaggtcgtg gtgaacgatg agaaccgtct tcccagcttt
    10501 tttcaaatct ctcagcgtat tcatgatgat ttcctcactg acagagtcaa tcccagcaaa
    10561 gggttcatcc aagaggatat agtcggcttc ctgcaccaaa catctggcaa tcaagacccg
    10621 ctggaattga cctccagaca gttgactaat ttgacgttca gcgtagtcag ctaggccgac
    10681 gatttcaagg gcctcttgca ctttcttcca atgtttagcc tttaaacttc gaaagagagg
    10741 aatagaggga aatagtccta acgagacgca ttccttgacc ttgatgggaa agttgtagtc
    10801 gatattgatt ttttgttcga cataggcaat tcggtgtaag gattttttaa cttccttgtc
    10861 atcgagaaat gcctgacctt gatgtgggat aattcccaac atacctttta atagtgttga
    10921 tttcccagcg ccgtttggac caatgatgcc ggtaattgtt ggtccatgga gcactagtga
    10981 aatatcctta agtgccaacg tttctttgta ggagacactg aggttttcga tacgtatcat
    11041 aaacttgtat tcctcctgtc tcttaatata cattaaaaaa aaaattaagt caagttaatt
    11101 tttgaaaaaa ttaaaataat aactgaaaaa tagattctaa aaataacttt caggataaat
    11161 ttctaaatta taaaacgcat agtatcaagt gtaaaaaact tggaattatg cgttttatca
    11221 tggaaaggtt ttttataata gctaaaaaat aatagttaaa tggttattaa ttgcattccc
    11281 tagtgatttt tgttaagata aaggcaaata caaatgaaag cgagaacaag atgacacgtt
    11341 atcaagatga tttttatgat gctatcaatg gagaatggca acagacagct gaaatcccag
    11401 cagataagtc tcaaacagga ggttttgttg atttagacca ggaaattgaa gacctgatgc
    11461 tggcgacaac agacaagtgg ttagcaggtg aagaagtgcc tgaggatgct atcttggaaa
    11521 actttgtcaa ataccaccgc ctagttcgtg attttgacaa gagagaagct gacggtatca
    11581 cacctgtctt accactcctt aaagaattcc aagaattgga aacttttgcg gattttacag
    11641 ctaaactagc agagtttgag cttgcaggaa aaccaaactt ccttcctttt ggtgtatcgc
    11701 cagactttat ggatgctaga atcaatgttc tatgggctag cgctccaagc acaatcttgc
    11761 cagatacgac ctactatgca gaagaacatc ctcagcgcga agagctcttg actctttgga
    11821 aagaaagtag cgcaaatctc ctcaaggctt atgatttctc tgatgaagaa attgaagact
    11881 tgctagaaaa aagacttgaa ttggaccgcc gagttgcggc agtggtgctc tctaatgaag
    11941 aacgttcaga atatgctaaa ctctatcatc catattctta cgaagatttc aagaaattcg
    12001 cgcctgccct acctttggat gacttcttca aagcagttat tgggcaatta ccagacaagg
    12061 ttattgtaga cgaggaacgt ttctggcaag cagcagagca attttacagt gaggaagcct
    12121 ggtctctcct taaagcaacc ttgattttga gtgttgtcaa tctttcaacc agctatttaa
    12181 cagaggatat ccgtgttttg tctggtgcct acagccgtgc cctttctgga gttccagagg
    12241 caaaagataa ggtcaaagca gcttatcatc tagcacagga acctttcaag caagccctgg
    12301 ggctttggta cgcccgtgag aagttctctc cagaagccaa ggcggatgtg gagaaaaaag
    12361 tggcaaccat gattgatgtc tataaggagc gtctgcttaa gaatgactgg ctcactccag
    12421 aaacctgtaa acaggctatc gtgaagctca atgtgatcaa accttatatt ggctatccag
    12481 aagaattgcc tgcacgttac aaggataagg tagtgaatga aactgccagt ctttttgaga
    12541 atgctctagc ctttgcgcgt gtggaaatca agcacagttg gagtaagtgg aaccagcctg
    12601 tagactataa ggaatggggc atgcctgctc atatggtcaa tgcctactac aatcctcaga
    12661 agaacctgat tgtctttcca gcggccattt tacaggcgcc tttctatgac ttgcatcagt
    12721 catcttctgc taactacggt ggtattgggg cagtgattgc ccatgaaatt tcccacgcct
    12781 ttgatactaa cggggcttcc tttgacgaaa atggtagcct caaggattgg tggacagaga
    12841 gcgactatgc tgccttcaag gagaaaacac aaaaagtcat tgaccaattt gatggacagg
    12901 attcttatgg agcaaccatt aacggtaaat tgactgtatc agaaaacgtg gctgacttgg
    12961 gaggaatcgc agcagctctt gaagcagcta agagagaagc agacttctca gcagaagagt
    13021 tcttctacaa cttcggtcgc atctggcgca tgaaaggtcg accagaattt atgaaacttt
    13081 tggctagcgt cgatgtgcac gcaccagcca aactccgtgt caatgtgcaa gtaccaaact
    13141 tcgacgattt ctttacaacc tatgatgtca aagaaggaga cggaatgtgg cgttcaccag
    13201 aggagcgcgt gattatttgg taatgcaaaa aatctagtca tcagaaaaaa ggcatccaat
    13261 cacgtgtgaa aaccttgata ggatgccttt tataatagaa agatttgctg gatagtttac
    13321 ttaaatttcg attgtcatca tcttgctaaa aaaagggatt gaaggctttt tcgtgagcga
    13381 tagtagtagc tggaccatgt cctggataga catcgtagtt tggtagggtg aagagttggg
    13441 tctggatact atgaaggagt tgctccatgc taccagtcgg aaggtcggtc cgtccgatag
    13501 tttcgcggaa tagagcatct cccgtcaaga ctaggtaagc atcaggaaag actagggaaa
    13561 caccaccgat agagtgccct ggggtcggta gaaccttaaa acgaaattcc tctagttggt
    13621 attcttcgtg aaagacaaag gtgtgttctg caggttttgt gaccacatct gccatatcat
    13681 cgtggcgagg gagaccggag agattatcga caggagtgta gagccagctg gcttcgctct
    13741 ctgcgatata gacaggagga ttgccaaacg tctcgcgaac caagtccaga ctcatgatat
    13801 ggtcataatg ggcgtgggtc aagagaatag cacagatcgg tttgttgatc ttctcgattg
    13861 tctgacgaat ggcttcccaa tgactaccag gatcgacgac gatgaggtgc ttttcgcctt
    13921 ctagataata ggtattttca taggcaacag gattcacggt tttatggatt ttcatactag
    13981 ctccaatctc aaagaatgta ctaatactct tcgaaaatct cttcaaaccg cgtcaacttt
    14041 atctgcaacc tcaaagcagt gctttgaaca gcctgcggct agctttctag tttgctcttt
    14101 gattttcatt gagtataaat taagtatagc acagttaggg agaataggta aggatttaaa
    14161 atgaacttaa aaatcagcat gactagatga agacaggctg gttatcaatt tatcaatatt
    14221 ggaaaggtgt caattgccct tcataggttg cataaactcc gtcattagct tgtttgatag
    14281 acgtgatgtt tagagtgcta ccgtagttgg cttctcattt gtcgctatat tcactataag
    14341 ttatcctact gggcaggttc tggtcgttag catagtattg aacgagtttt ttatagcttt
    14401 gctggctgaa taggaacagg cagcaaactc ctaacattag gagagcaaag atagaaatag
    14461 cagttttttt cataggtatt ctccttataa actaaaggat agaagaaagt atcttgagga
    14521 tttttatact cttcaaaaat ctcttcaaac cgcgtcaact ttatctgcaa cttcaaagcg
    14581 gtgctttgag taacctgcgg ctagtttcct agtttgctct ttgattttca tttagtatta
    14641 attccaaaat ccagtcaagg taccagtgta tgtgctacga gttccaccgt ttatctttcg
    14701 tattttcaat ggaattgggg aagtcagaaa gtctttgggt tacaatatgg tttccgttct
    14761 tctatctctc cttctatcac ctaagtttaa aatctaactt cgtagtatat tatgggctaa
    14821 taattcagaa ttatcaagca attttgaatt atttttttct tattctgttc caatctagtt
    14881 ttcatattct taaaaaagtg ataaaatggt aggaagaatt ggagagtaga gatgccgaaa
    14941 gaagtgaatt taacaggcga agaagttgtc gctttaacca aagaatattt aacggaagag
    15001 gatgttcatt ttgtccataa ggccttggtc tatgctgttg aatgccacag tggtcaatat
    15061 cgcaaatcag gcgagcctta tatcattcac cctatccaag tggcaggtat tttagctaag
    15121 ctaaagctgg atgctgtaac agtagcttgt ggattcttgc atgatgtggt ggaagataca
    15181 gatgcgactt tggacgattt ggaaagagag tttggtcctg atgtgcggat gattgttgac
    15241 ggagttacca agcttggcaa ggtcgagtac aaatcgatcg aggagcaatt agcggaaaat
    15301 catcgcaaga tgctcatggc catgtctgag gacatccgcg ttattttggt caaactgtct
    15361 gaccgcttgc acaatatgcg gaccctgaaa catcttcgaa aagacaagca ggagcgtatt
    15421 tccaaagaaa ccatggaaat ctatgcccca cttgcccatc gtttggggat ttccagtgtc
    15481 aaatgggaat tagaagactt gtctttccgt tatctcaatc caacggagtt ttacaagatt
    15541 acccatatga tgaaggaaaa gcgcagggag cgtgaggcct tggtggatga ggtagtcaca
    15601 aaattagagg agtatacgac agaacgtcac ttgaaaggga agatttatgg tcgtcccaag
    15661 catatttact caattttccg caaaatgcag gacaagagaa aacggtttga ggaaatctat
    15721 gatctgattg ctattcgttg tattttagat acccaaagtg atgtttatgc catgcttggt
    15781 tacgtgcatg aattttggaa accgatgcca ggtcgcttca aagactatat tgccaaccgc
    15841 aaggccaatg gttatcagtc tatccatacg actgtttatg gaccaaaagg gccgattgaa
    15901 ttccagattc gaaccaagga aatgcacgag gtggctgagt acggggttgc ggctcactgg
    15961 gcttataaga aaggtataaa ggggcaagtt aacagcaagg aatcagctat tggaatgaac
    16021 tggatcaagg agatgatgga gctccaagac caggctgatg atgctaagga atttgtggac
    16081 tctgttaagg aaaactattt ggctgaggag atttacgttt ttaccccaga tggagctgtc
    16141 cgttcccttc ccaaagattc aggaccgatt gattttgcct acgaaatcca taccaaggtc
    16201 ggtgaaaaag caactggtgc caaggtcaat ggccgcatgg ttccactgac aaccaagtta
    16261 aagacagggg atcaggttga aattatcgcc aacccgaact cctttggacc tagccgtgac
    16321 tggctcaata tggtcaagac tagcaaggcg cgcaataaga ttcgccagtt ctttaaaaac
    16381 caagataagg aattgtctgt caacaagggt cgtgagatgc tgatggctca gttccaagaa
    16441 aatggctatg tggcaaataa atttatggac aagcgccaca tggatcaagt tctgcaaaag
    16501 accagttaca agacagaaga ctccctcttt gcggccattg gttttgggga aatcggtgcg
    16561 attaccgtct ttaaccgtct gactgaaaag gaacgccgtg aggaagagcg tgccaaggcc
    16621 aaggctgagg cagaggagct tgtcaaaggt ggcgaggtca aggttgaaaa taaagaaact
    16681 ctcaaggtca agcatgaggg gggagtggtt attgaaggtg cttctggtct cctagtgcgg
    16741 attgctaagt gttgtaaccc cgtgcctggt gacgatattg ttggctacat taccaagggt
    16801 cgtggtgtgg ctattcaccg tgtggactgt atgaacctgc gtgcccaaga aaactacgag
    16861 caacgtctcc ttgatgtgga atgggaagac cagtactcta gctcaaataa ggagtatatg
    16921 gcccatatcg atatctacgg tctcaaccgt acaggactgt tgaacgatgt actgcaagtt
    16981 ctttcaaata caaccaagaa tatttcaacg gtcaatgccc aaccaaccaa ggatatgaag
    17041 tttgctaata tccatgtgtc cttcggtatt gccaacctct ctacactgac cacggttgtc
    17101 gataaaatta agagtgtgcc agaagtttac tctgtcaaac ggaccaacgg ctagttgtcc
    17161 tagctcttac tagaaaggct attatgaaaa tcattatcca acgggttaaa aaagcccaag
    17221 tgagtataga aggccagatt cagggaaaaa tcaatcaggg acttttattg ctggttggtg
    17281 ttggaccaga ggaccaagag gaagatttgg actatgctgt gagaaaactg gtcaatatgc
    17341 ggattttttc agacgcagaa ggcaagatga acctgtctgt caaagatatt gaaggagaaa
    17401 tcctctctat ttctcagttt accctctttg cggatactaa gaaaggcaat cgtccagcct
    17461 ttacaggggc agctaaacct gatatggcat cagacttcta tgatgctttc aatcaaaaat
    17521 tagcgcaaga agtgcccgtt cagacaggta tctttggagc agatatgcag gttgagctgg
    17581 ttaataacgg acctgttacc attatcctag atactaaaaa gagataagaa agaccaagcc
    17641 cagtcggctt ggtctttctc atcgatcata aaatactcca aaaagaaatc ggttcttgat
    17701 atgcttgggg gaagtctctt ttcaggcttt ggcagatgcg ataggaaggg atgagatgtc
    17761 ctaggatgag gagagttccc tgaaggaaaa gtggaatatc acttaaagac accaaggaga
    17821 gaatcatcag gctatcccat aggagaattt gtaaagcaaa acgtcagaat ctcggtctaa
    17881 tctgggaata gagttgacta aagtggtcac aaagttggtt tgaaagatag gtcaatagca
    17941 caggatgaaa gaaaatgagc caaccactat aaatcaaaat ccagtcccaa gtaagccccc
    18001 ttttaaatgt caaaaatgcc agcatgattc catcaatgac aaggagttga atggttttga
    18061 tgaagatgat ttttttcatg ctaaaacctc cttttttcat ctgttagtga cgtaatgctt
    18121 tatataatta ttatacagta ttcagtcggg atatgaaaac gtttactatc gtttttgata
    18181 taaaaaatag ataagaaaac cctgaaaata aaactttcag ggttggtagg ggacttgaga
    18241 aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac ttgtaaatcc
    18301 tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt gacttggagc
    18361 tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa actatcgtgc
    18421 acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag gttattgatt
    18481 tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt tttagggaaa
    18541 cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc caagacctca
    18601 gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa aacttcaatc
    18661 aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt cagtagatag
    18721 ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat catttcagtt
    18781 acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat cttatgcagg
    18841 tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt cattcgtttc
    18901 ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct agctgtgact
    18961 ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg aaaatagctc
    19021 ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca gatgctcagc
    19081 agctaggagt ggatgaatac tggcttttgg gagatattct catgccaggg acaggacgta
    19141 gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg ggaaactggg
    19201 aagacagtct ttggcatggt gtccgtaagg aattggacag tactcgcccc agtcaacgct
    19261 atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa attgaagtgc
    19321 tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg ggaattagcc
    19381 atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa caagaggagt
    19441 ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat attcaccagc
    19501 agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg attggccaac
    19561 ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg attttggagt
    19621 ttgatgacaa gggtctggta gatatggact tccgacgggt agactacgat gtggcagcgg
    19681 aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat gaaagtctgg
    19741 tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct cagaaagagg
    19801 gctgcgatcg ggagttagac gactggttga aaagtggtaa cgattgacat tacaactaaa
    19861 aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa aaggagaaga
    19921 ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc attgccctcg
    19981 aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg gtcaatcctg
    20041 tcattatcag aaatatcttg tcccagttga agaaggcaga gctgatttca gtagcgcgtg
    20101 gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta gatgtttatc
    20161 aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac aatccgaatc
    20221 caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg gagagaattc
    20281 agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg gccgatgcag
    20341 agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga taattatgat
    20401 aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt attagccttt
    20461 atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt tttattatcc
    20521 ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata cgagaatgtt
    20581 cagttagctt tttatgtatt tacctttgtc ttacttcctt ttttgctttt tctaagtggc
    20641 atctttttaa tctataatgg ggtcattttg ttgaagtgag agggacgttc caagccccat
    20701 tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa agacttagaa
    20761 tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt ttcaagagta
    20821 ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa ggcgacccaa
    20881 ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat gaatgtattc
    20941 aagcgccttt aaggaagcca agtcgttgat agagctaata ccagcatcaa gaatagtgcc
    21001 aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca cccattcttt
    21061 aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga cgaagtgctt
    21121 gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg cagtactctg
    21181 aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac cttgtggaat
    21241 gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca attcttgatg
    21301 gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac tttgctcaat
    21361 ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcca gaataacctt
    21421 ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct tttgagcagg
    21481 aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac tgtcatctgt
    21541 cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag ccgcaaattg
    21601 cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat ttttgaagcg
    21661 cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa gcatggtggg
    21721 ctctcttgga acctgaggtg ctagctctaa aagacgttga ggaagtgtgg agaccagatt
    21781 atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat tcaagggaag
    21841 gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg ccataagagc
    21901 tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc attgcctgtt
    21961 tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc atggaaaaat
    22021 ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattagtg gaagatgatc
    22081 aggtcattcg tcaacaggtt gggaaaatgc tctctgaatg gggatttgaa gtggtcctgg
    22141 tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat ctggtcctca
    22201 tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc cgcaagattt
    22261 ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt gtcatggcaa
    22321 tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt cttttagcta
    22381 aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt ttgctggaat
    22441 atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg caagtcttga
    22501 atttgaccaa gaacgaattc cagattttac gcgtgttatt tgagcatgca ggcaacatcg
    22561 tagcacgtga cgacctgatg cgagaacttt ggaacagtga ctttttcatt gatgataata
    22621 ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga ttggtaggat
    22681 ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg gaaacaattt
    22741 tttctagcct atctgcgctc ccgtagtcgt ctttttgtct atctgctttc tttggcattt
    22801 ctggtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct ctactttttc
    22861 ctcttgtgtt gctttgtaac catcttattt ttcacttggg acatattggt ggaaatgcag
    22921 gtttatcgcc aggaacttct ctatggagag agggaagcca agtctccttt ggaaatagct
    22981 ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc aaaagcagaa
    23041 agaaaactga cggatttgct ggattactat accttgtggg tccatcagat aaagaccccc
    23101 attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa gcagcagcta
    23161 gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta cctgcgttta
    23221 gaaagtttcc atgatgattt gctcttaaag caggttcaaa ttgaggactt ggtcaaggaa
    23281 ataattcgta aatatgctct tttctttatt caaaaaggct taaatgtcaa tctacatgac
    23341 cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga gcaaatcatc
    23401 tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga tgaccaagag
    23461 ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg agtatttgaa
    23521 cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact tggcctttat
    23581 ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc tgaggtcgga
    23641 aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga gtaaaaatag
    23701 atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct caacgcgtga
    23761 tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga cagtttgtgt
    23821 ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt tgtctccaac
    23881 aattaattgg taaggaatct tgctggtttg tgaagcacgg atcttgaact gcattttttc
    23941 attgcgctca tctacatctg cacggacacc gcggtcacgg agtttcttgg ccacttccca
    24001 agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt gtggtgccag
    24061 ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc gttccatagt
    24121 tgagataact ccacggtgga tcatgactgg acggtgatct tcgccatcag ctccgatgta
    24181 tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa gggtttcttc
    24241 ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg ctgcttcacc
    24301 ttcggcttca aagtagtcca cgcccatttc atcaagagct gcacgaagca tggtttgggc
    24361 attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt cacgaagaga
    24421 gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa tcaactgaag
    24481 ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac cgtcgttgag
    24541 tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt aacggtgcat
    24601 cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat ggtgtttaaa
    24661 aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc cgtcacccat
    24721 gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag tcttgtaaag
    24781 ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca actctttgtt
    24841 tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc agaatggcaa
    24901 accttgtccc acttcttgtg aaatcataaa gaggtcaagc tctttaccaa gtttacggtg
    24961 gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt tcttgtcaaa
    25021 ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac gccagtacgc
    25081 accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa cgtgaggtcc
    25141 acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt cgtcttctga
    25201 gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac gtgcctcgtc
    25261 tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt gcatttcttc
    25321 ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag tatcgtagta
    25381 gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa gacgacgagc
    25441 tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat cttcgtgatc
    25501 aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt cgatgagttt
    25561 gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag attgggcaat
    25621 ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga aagtaatgtt
    25681 aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt ttttatcagc
    25741 agactacttc cgagtcctaa cgttcaattg cttttcttta tcagagagga agtttttcat
    25801 ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc agatattttc
    25861 tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt gctttgtcat
    25921 caccagtcat tggaaatttc caatatcatt agataaagcc aagaggtctt cttctaccgt
    25981 ccacttgaaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga ttgcccaact
    26041 gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat gcgacatcct
    26101 cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga gagggacacc
    26161 tctgatcggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca agagtagtat
    26221 cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa agggactaag
    26281 tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga ttttgtgaaa
    26341 gttttttgtt tttcattttt tgtagaatat gcttgatgct aataccagaa tccatgccga
    26401 ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca aaggttatga
    26461 tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa cggaaacggt
    26521 agctatagag taacgatata atcaagatta ccagaggtgt aaagaagaga agattgttta
    26581 tatagagttc cttgagtgta agggggtcag aaacaactag taagaacaac tcataaagtg
    26641 gccaataaaa gaataatatg accagatagt aggggagatg ggaatagaat ctacgcatga
    26701 taatcacctc gttttaaaaa aacagacaac ttagatctct tgctatgatt attatagcat
    26761 gtttaaaaca agaaagtaaa tttgttgaca aagaagattt ttcttttcac tagaatcata
    26821 gttagttttc ttggtagaaa tattttgata ataattaagc aagactattg acattaatta
    26881 ttaagagtgt cacaattgtt gtaactaaaa taattacaac aagagaggta taaaaaatga
    26941 aactagcagt tattgcagca aatggacaag cggggaaagc aattgttgaa gaagcagtca
    27001 aacgaggaca tgaagtaacg gctattgttc gttctgaaaa caaaagtcaa gctgagtcta
    27061 ttattaaaaa agatttattt gagttgacaa aagatgatct tactggattt gatgctgtta
    27121 tttcagcgtt tggtgcttat acaccagata cgctaccgct ccacagcaaa tcaatcgaac
    27181 tatttaatca gcttcttgct ggaacacaga cacgttttct agttgtaggg ggagcaggaa
    27241 gtctttatat agatgaaaca aaaacgacac gacttttaga tacgtctgat tttcctgaag
    27301 aatttaagtc actagcaaaa gctcaagcgg atgaattgga tcttcttcgt acaaaaaata
    27361 atctcaactg gacttttgtc agtcctgctg tagattttat tcccgatggt gaaaaaacag
    27421 gaaactacat tctagcagga gaaattttta ctactaatgg aaaaggaata agccagatta
    27481 gttatgcaga ttatgctatt ggattggtag atgaacttga aaaaggtcat catataaaag
    27541 aacgtatctc tttacttgaa aaataataac tatgagagta ttaatgtttg acagaaaatt
    27601 taaatcttgg taaaataagg attgtcgtaa agacaaataa cttcttcttg gttacaggca
    27661 tgccaacctg tcactcggat gaagccaaat aaaaaggaga aacatcatgg caatctcaaa
    27721 agagaaaaaa aatgaaatca ttgcacaata tgcacgtcac gaaggtgata caggttcagt
    27781 agaggttcaa gttgctgtcc ttacttggga aatcaatcac cttaacgaac acatcaaaca
    27841 acataaaaaa gaccacgcta cttaccgtgg attgatgaaa aaaatcggtc gccgtcgtaa
    27901 cttgcttgca tacttgcgta aaaacgacgt taaccgttac cgtgagttga tcaactctct
    27961 aggacttcgt cgctaattca agatacaaat gctgtcaaaa gcacaaagca aaaataggaa
    28021 aattgacgaa gaaacttcag tttctaggag attttatctt ttttgccaag tgcttaggcc
    28081 gtgttcaatt gagcatatct tgataataaa gctactctaa attgggtagc ttttttgcgt
    28141 tgtcacctta cctcgatata ctcaagtata atctttggtt acggttccta gcactgtaag
    28201 gtaaaataaa ccagcttttc tcccttcggg gagatttttt tgtttcactg aaagtttcgt
    28261 acgatcttcg cctcgtcgcc tagtctataa acgatttatc tagcaagaat catgatgcta
    28321 agggcgtcaa aaatccgtat gaaaataggg aaatgacaca gtgttcgatg agcacaagga
    28381 gtttcatctt tttcactagg attttagccc gggctcaaat cagctctctg acttcagagg
    28441 gcttttttat tgaggtttta tcggtaacaa ttttggagac tacaaaaatc tcaaacggta
    28501 tcagctaatt acaccataaa ggtgcgcagt tactcggctt ttcaagccga gtagctgtat
    28561 gcaagccccc tagaagagcc cactctttac aaagtaaagt atagtatgtt atactttaca
    28621 tggaagtagt cactgaattc cagttagaaa ttactttgta actacgtttt gaggaggagt
    28681 aaaatgcttt cctacgttcg acattaccca ctagcgatag ctaaattaat gtgtctgtgc
    28741 tctcctaaaa tctgctgatt tattactgac taatacagga gtttttttta tgggacagac
    28801 aatcatatct gctattggtg tttatatttc caccagtatc gattatttaa ttattttaat
    28861 tattttattt gcacagctat cacagaataa acagaaatgg catatttatg cggggcaata
    28921 tctaggcaca ggcttacttg taggggcgag tttagttgct gcttatgtcg ttaatttcgt
    28981 gcctgaagaa tggatggttg gattgcttgg tttaatccct atctatttag ggattcgctt
    29041 tgcaattgtt ggagaagatg cggaagaaga agaggaagaa attattgaaa gattagaaca
    29101 aagcaaggca aatcaactgt tttggacagt tacattgctg acaattgcgt ctggcggaga
    29161 taatttaggt atctatatac cttattttgc ttcgttagat tggtcacaga ccctcgtggc
    29221 cttgcttgtg tttgtaatcg gcataattat cttttgcgag attagtcggg tgttatcctc
    29281 tattccgtta atattcgaga caattgaaaa atacgagcga atcattgtgc ccttagtatt
    29341 cattctactt ggactataca tcatgtatga aaatggcacg atagagactt ttctgatcgt
    29401 gtagattttt ttgtttcact aggattttag tccgagctca aatcagctct ctgattttca
    29461 gagggctttt tcattgagta taaatggaca atcttaaagt tactctattg tagagtggct
    29521 tttgatttga ttaggagatt cttataaata tagtaaaatg aaataagaat aggacaaatc
    29581 gatcaggaca gtcaaatcga tttctaaaaa tgttttagaa gtagaggtgt actattctag
    29641 ttccaatcta ctatataaat gaaaacctta gctgtttcgc caaggttcat ttcttctatg
    29701 caagttcttc tcttttctta tctgggttcc agatgaagct tgcgataaag ctaaagatga
    29761 tggttaggat agcgaggata atagcaagga tgagggcagg gatgcggata aaccaccaga
    29821 gtggatttgg ttttttatca ttgtgccatt gtttcgtttc ttcgtccaga cgttggaatt
    29881 ctgtttgaat acgattggcg actgtttcaa tgccttcatc attcattttc ttgatatctg
    29941 agatatcgat tggatttcca aagttcatat cgacacgttc acggctaatc aagcccttca
    30001 aagtcatggg accggtgtag gtaaccggca tgatacggac cttggccatt ttggcaatca
    30061 gtgctgcgcc ccccttgaca tcgtttgagt ggcggctacc acttggaaac atgatgagag
    30121 agcggtcact ttttttgaga acgttgatag gatatttgat ggctgaggcg ctgggatttt
    30181 cacggtcgat gggaaaggcg ccacacatac gaatccacca accaaagata cggttggtaa
    30241 agagttcttt ttttgccata aagatgaact gttttggctt ggtcgcaaag gccatataaa
    30301 caggatccca ccaggtacgg tgaggcgcaa ctaaaatata attttcatct tgattaggaa
    30361 ttttattagt attatgatag tgagcattgc cattgatgga ccataagagc aatacaacta
    30421 atccacgcaa ataagtataa aacatgcgat ctccttcgat tgttttcttg ttattattat
    30481 accttatcaa aggagggctg gcaaactttt cccttgacta gatgcatatt tgggatgaaa
    30541 ttagaattct gttaaaaaaa atgatataat agaatttatg gataaaaata agattatggg
    30601 attaacccaa agagaagtca aggaaagaca ggctgagggt ttggtcaatg actttaccgc
    30661 atcagccagt accagcactt ggcaaatcgt taaacgaaat gtctttaccc tttttaacgc
    30721 tttgaacttt gccattgctt tggctcttgc ctttgtgcag gcttggagca atctggtctt
    30781 ctttgctgtt atctgcttta acgctttttc tgggattgtg accgagctac gagccaaaca
    30841 catggtggac aagctcaatc tcatgaccaa ggaaaaggtc aaaaccatcc gtgatggtca
    30901 ggaagttgct cttaatcctg aagaattagt gctaggagat gtcattcgtt tgtctgcagg
    30961 agagcagatt cctagtgatg ccttggtttt ggaaggcttt gcggaagtca atgaagccat
    31021 gttaacggga gaaagtgatt tggtgcaaaa ggaagttgac ggcttacttt tgtcaggaag
    31081 tttcctagcc agtgggtcag ttttatctca agttcaccat gtcggtgcag acaactatgc
    31141 tgccaaactc atgcttgagg ctaagaccgt taaacccatc aactcccgta tcatgaaatc
    31201 gctggacaag ttggctggtt ttactgggaa gattatcatt ccctttggtc tggctctctt
    31261 gctggaagcc ttgcttttaa aaggcctgcc tctcaagtca tccgttgtaa actcgtcgac
    31321 agctcttttg ggaatgttgc ctaagggaat tgcccttttg accattactt cgctcttgac
    31381 tgcagtgatt aagttgggct tgaaaaaggt cttggtgcag gagatgtact ctgttgagac
    31441 cttggcgcgc gtggatatgc tctgtctgga caagacgggc accatcaccc aaggaaagat
    31501 gcaggtggag gctgttcttc cactgacgga aacttacggt gaagaggcta ttgccagcat
    31561 cttgactagc tacatggccc atagtgagga taagaatcca actgcccaag ccattcgcca
    31621 gcgttttgtg ggagatgttg cttatcctat gatttccaat cttcccttct cgagcgaccg
    31681 caagtggggg gctatggagt tagaaggctt ggggacagtt ttcttagggg cacctgagat
    31741 gttgctggat tctgaagtcc cagaagccag ggaggccttg gagagaggat cacgtgtctt
    31801 ggtcttagct ctcagtcagg agaaattaga ccatcacaaa ccacagaaac catctgatat
    31861 tcaggctcta gccttgctgg aaatcttgga ccccattcga gagggagcag cagagacgct
    31921 ggactatctc cgttctcagg aggtgggact caagattatc tctggtgaca atccagttac
    31981 ggtgtccagc attgcccaga aggctggttt tgcggactat cacagctatg tagattgctc
    32041 aaaaatcacc gatgaggaat tgatggccat ggcggaggag acagctattt tcggacgtgt
    32101 ttcccctcat caaaagaaac tcatcatcca aacgttgaaa aaagcgggtc atacaacggc
    32161 tatgacaggg gacggggtta atgatatctt ggcccttcgt gaggcggatt gttctatcgt
    32221 gatggcggag ggggatccag caacccgtca gattgccaat ctggttctct tgaactcaga
    32281 ctttaatgat gttcctgaga ttctcttcga gggtcgtcgc gtggtcaata acattgccca
    32341 catcgccccg attttcttga taaagaccat ctattccttc ctgttagcag tcatctgtat
    32401 tgccagtgct ttactaggtc ggtcagagtg gattttgatt ttccccttca ttccgatcca
    32461 gattaccatg attgaccagt ttgtggaagg tttcccacca ttcgttctga cttttgagcg
    32521 aaatatcaaa cctgtcgagc caaacttcct cagaagatcc atgcttcgtg ccctaccaag
    32581 tgccctcatg gtcgtgtttg gcgttctttt tgtgaaaatc tttggaacga gtcaaggttg
    32641 gtctgagtta gaaatctcaa ctctcctcta ttatctcttg gggtcaattg gtttcttatc
    32701 cgtatttaga gcctgcatgc cattcactct atggcgagtc ctattgattg tctggtcagt
    32761 aggaggcttc ctagccacag ctctcttctc aagaattcaa aaactgcttg aaattgcaac
    32821 cttaacagga caaacattac ctgtttatgg tgtcatgatg ttggtcttta ccgtgatttt
    32881 catcctgacc agtcgttacc aagcgaaaaa ataaagaaag actgcaatct gtggattgca
    32941 gtttttttag gtacaagatt gccagccgaa atgtggtata ataagaggta atagagtttt
    33001 ggaaagtgag agaagatgat ttcaaagaga ttagaattgg tagcttcctt tgtgtcacag
    33061 ggggctattt tactagatgt gggaagtgac catgcttatc tgcctatcga gttggttgag
    33121 agaggccaaa tcaaaagcgc tattgcaggt gaggtggtgg aaggtcccta tcagtctgcg
    33181 gttaaaaatg ttgaggctca cggcctaaag gagaaaatcc aagtccgttt agccaatggc
    33241 ttggcagctt ttgaagagac tgaccaagtg tctgtcatta ccattgctgg catgggtggt
    33301 tgtttgattg ctaggatttt agaagaaggt ttggggaagt tagctaatgt agagcgtttg
    33361 atcctccagc ccaataatcg tgaagacgac ttgcgtatct ggctacagaa tcatggattc
    33421 cagattgtag cagaaagcat cttagaagaa gctggcaagt tttacgagat tttggtggtg
    33481 gaagcaggac aaatgaagct atcagccagt gatgttcgct ttggtccctt cttgtccaaa
    33541 gaagtcagtc cagtatttgt ccaaaaatgg caaaaagaag ctgagaagct agagtttgcc
    33601 ctcggacaaa tcccagaaaa aaatctggag gaacgtcaag ttctagtaga taagattcaa
    33661 gctatcaagg aggtgctcca tgttagcaag tgaagtgatc caagcttatg aagccttttg
    33721 ccctcaggaa ttttctatgg agggagacag ccgtggtctg caaattggca ctttagacaa
    33781 gggtatccaa agggtcatgg ttgccctcga tattcgtgaa gagacggtgg cagaggccat
    33841 tgaaaagggt gtggacttga ttatcgtcaa gcacgcgcct atctttcgtc ctatcaagga
    33901 cttgcttgcc agccgtccgc aaaatcagat ttacatcgac ctgattaagc atgacatcgc
    33961 agtttatgtc agccatacca atattgatat cgttgaaaat gggctcaatg actggttttg
    34021 tcagatgcta ggaatcgagg agacgactta tctgcaggaa acaggtccag aacgtggaat
    34081 tggacgtatt gggaatattc agcctcagac attttgggaa ttggcccaac aggtcaagca
    34141 agtctttgac ctagatagcc ttcgaatggt gcattatcaa gagaatgatt tgcagaagcc
    34201 tatttcaaga gtagcaattt gtggtggaag cgggcagtct ttctataagg atgctttggc
    34261 aaagggggca gatgtctata tcactggtga tatctactac catactgctc aggatatgct
    34321 gtctgatggc ttgttagcat tggatccagg tcactatatc gaagtgcttt ttgtggaaaa
    34381 aatcgcagca ctccttactc aatggaaaga gaaaaaaggc tgggaactag agattttacc
    34441 tagtcaagca tcgaccaatc ctttccgtca tatctagtta gaaagtgaag acaatgaaaa
    34501 aagttgccat tattggagca ggaattgtgg gagcaacagc tgcctactac ctctcgagag
    34561 aaagtgacct agaggtgacc gtttttgacc atgagcaagg tcaagccacc aaggccgcag
    34621 caggaattat cagtccttgg ttttccaaac gccgtaataa agcctggtac aagatggcgc
    34681 gcttgggggc tgacttttat gtggatttat tagctgattt agagaaatca ggacaaaaaa
    34741 tcgactttta ccagcgttcg ggagtctttc tcttgaaaaa ggatgaatcc aagttggaag
    34801 aactttatca actggccctc cagcgcagag aagaatctcc cttgataggg caattagcca
    34861 ttctggacca agcttcagct aatgaattat tccctggttt gcagggattt gaccgcctgc
    34921 tctatgcttc tggtggagcg agagtagatg gccaactctt ggtaactcgt ctgctagaag
    34981 ccagtcatgt caagctggtc aaagaaaaag tgactctgac actcttatca tcaggctacc
    35041 agattggcga agaggtgttt gatcaggtta ttttggcaac gggagcttgg ttgggggaca
    35101 tgttagagcc tttaggttat gaagtggatg tccgtcctca aaaaggacaa ctacgagatt
    35161 atcagcttgc ccaagacatg gaagattacc ctgttgtcat gccagaaggg gagtgggatt
    35221 tgattccctt tgcaggtggg aaattatcct tgggcgctac ccatgaaaat gacatgggat
    35281 ttgatttgac ggtagatgaa cccttgctcc aacaaatgga ggaggcggcc ttgcctcatt
    35341 acccagtttt agctagagcg acttcaaggg ctgagcgtgt gggaatccgt gcctatacca
    35401 gtgatttctc tcccttcttt gggcaggtgc cagaattggc aggtgtctat gtagccagtg
    35461 gactaggttc atcaggcctc acaactggtc ctatcattgg ttaccatcta gcccaactga
    35521 tccaagacaa ggagttgacc ttggaccctc taaattatcc aattgaaaac tatgtcaaac
    35581 gagtaaaaag cgaataatac tcaatgaaaa tcaaagaaca aactaggaaa ctagccgcgg
    35641 gttactcaaa gcactgcttt gaggttgtgt atagaactga cgaagtcagt aaccataccc
    35701 atggcaagga gacgttgacg tggtttgaat tggattttcg aagagtataa gcattttact
    35761 gaaattttat caggtagttt aggatggcaa atgacattcc ctgtcaaaaa tggtaaaata
    35821 agaaaaaata atctgagaat cgaggaaaaa agatgcaaga aaagattttg gtaactggtg
    35881 gtgccggttt tattggaacc cacactgtta ttgaattgat ccaagcaggc catcaagttg
    35941 ttgtggtgga taatcttgtc aatagcaatc gtaagagttt agaagttgtt gaaagaatca
    36001 caggagttga gattcctttc tatgaggcag atattcgtga cacagttacc ctcagagata
    36061 ttttcaagca ggaagaaccg actggtgtca ttcactttgc tggtttgaag gctgttggcg
    36121 aatcaacacg tatccctctt gcctactatg acaacaatat cgctggaact gtcagccttt
    36181 tgaaagccat ggaagaaaac aactgtaaaa acatcatctt cagttcttct gcgacagttt
    36241 acggggatcc gcacacagtg cccatcttgg aagatttccc actttcagtg accaacccat
    36301 acggtcgtac caagctcatg ctagaggaaa ttttgaccga tatttacaaa gcagactcag
    36361 aatggaatgt tgtcttgctt cgttacttta acccaatcgg agcccatgag agtggtgatt
    36421 tgggagaaaa tccaaacggt attccaaaca atctcttgcc atatgtgact caagtagccg
    36481 ttggaaaatt agagcaagtg caagtgtttg gagacgatta cgatacggaa gatggaacag
    36541 gtgttcgtga ctatatccac gttgtcgatt tggctaaggg tcacgttgca gctttgaaaa
    36601 aaatccaaaa aggttcagga ctaaacgttt ataaccttgg aactggtaaa ggttactcag
    36661 ttcttgaaat tatccaaaac atggaaaaag cggtgggacg tcctattcct taccgcatcg
    36721 tagaacgtcg cccaggtgat atcgctgcct gctactcaga cccagcaaaa gctaaagcag
    36781 aactcggttg ggaagcagaa ctcgacatca cccaaatgtg tgaagacgca tggcgttggc
    36841 aaagcaagca tccaaatgga tttgaagact aagatgatga tttcaatcat cgtcccttgt
    36901 ttaaacgaag aggaagtact tcctcttttt tatcaggctc tggaagcttt acttccagat
    36961 ttggaaacag aaatcgagta tgtctttgtc gatgatggat caagtgatgg gaccttggaa
    37021 ctcttaaagg cctatcggga gcaaaatccg gcagtccatt atatttcttt ctctcgaaat
    37081 tttggcaaag aagcagccct ttatgcaggc ttgcaatatg cgacaggaga tttggtggtg
    37141 gtgatggatg cagacctcca agatcctcct agtatgttgt ttgagatgaa aaatgtacta
    37201 gacaaaaatg tagacttgga ctgcgttggg acacggagaa ctagtcggga gggagaaccc
    37261 ttctttcgca gtttctgtgc tgttctcttt tatcgcctca tgcaaaaaat cagcccagta
    37321 gctctgccgt cgggtgtccg tgactttcgt atgatgagaa ggtctgtggt cgatgccatt
    37381 ttaagcttga ctgagtccaa tcgtttttct aagggactct ttgcctgggt cggctttaaa
    37441 acccactatc tggactatcc aaatgtcgaa aggcaggctg gcaagaccag ttggagtttt
    37501 aggcaactct ttttttactc cattgaaggg attgttaatt tttcagattt ccctttgact
    37561 atagcctttg tagctggtct cctatcttgt tttctttctc tgctgatgac cttttttgtt
    37621 gtggttcgga ccctcatttt gggcaatccg acatctggtt ggacctctct gatggctgtt
    37681 attctctttc ttggaggcat tcaactcttg accattggga ttctcggtaa gtatatcagt
    37741 aagatttatt tagagactaa aaaaagacca ctttatctta tcaaagaaaa aagtgacctt
    37801 cctgatttta cagaaaaaat aaagtgaaaa gactataatt ttacatggaa atgtgctaaa
    37861 ctagagggag tggattatcg ccattgattt aggcttcctg gtttccaatc agggcgcgag
    37921 ttgggcaatt tttaacagcc tctaagacat cccgactagg agaaatttct ttttccagtt
    37981 ggtcagggtc atcgtaaaaa cgcacgattc cattatcgtg gtaatcaaat aaatcagaat
    38041 aagtttggca aagtccacag gcgatacatc gttcaggtat aagtgtgatt ttcatgttca
    38101 tatttatatt gtaataagaa aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc
    38161 gtggcaagaa gatatttatg atcaagaaga atcaagagca gggcgtcggc atcgaaacca
    38221 cggaggggct gataggatgg ctaatcgtat tttgacgatc ctagctagta ttttctttgt
    38281 aattgtggtg gtgatggtca tcgttctcat ctatctatca tcggggggga gtaatcgcac
    38341 agcagcctta aaagactttc atgattctga tgcaagtgta gtacaaatct catcttcaag
    38401 tagttctcag cctgagcaga gttcagagcc agaatctact tctagtagtt cagaagaagc
    38461 tgctaatcct gaaggaacga ttaaagttct cgcaggagaa ggggaagcag ctattgccgc
    38521 tcgtgcagga atctccattg ctcagttaga ggccttgaat cctgggcaca tggctacagg
    38581 atcttggttt gctaatccag gtgatgttat aaaaataaaa taggagccga tatgaaaaca
    38641 attcaaattg ctattgatgg tcctgcttcc agcggtaaga gtacggtcgc aaagattatt
    38701 gctaaggatt ttggattcac ctaccttgat acaggagcta tgtatcgtgc agcgacctat
    38761 atggctctta agaaccaatt aggagttgaa gaagtcgaag cccttctagc cttgttggac
    38821 cagcatccaa tcagctttgg acgttcagaa actggagacc agcttgtttt tgtaggagat
    38881 gtggatatta cccatcctat ccgtgaaaat gaagtgacca atcatgtttc tgctattgca
    38941 gcaattcctg aagtgcgtga gaaactggtt tctctccaac aagaaattgc ccagcaaggc
    39001 gggattgtca tggatggtcg cgatattgga actgttgtat tgccacaagc agaattgaaa
    39061 attttcctag tagcttctgt tgatgagaga gcagagcgtc gttacaagga aaatattgcc
    39121 aagggaattg aaacagacct tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag
    39181 gatagtcatc gtgagacttc tcctctcaaa caagcagagg atgctgtcta ccttgataca
    39241 actggtttga acattcaaga agtagttgaa aaaatcaaag cagaagctga aaaaagaatg
    39301 taaatgtaga aaagccgata gattgatatc ggtttttttc taaatttgtc aaaatgctga
    39361 ttttagggta taatagttgc tgttcgagaa attttgattt tcaaagaata gtgaatgatg
    39421 ataaggagaa accatgaaca atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta
    39481 cgaagacggt gccctactgg tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt
    39541 tgcagaagta gaagaaggtc ttgtcgctat cgatgccaac ggaaataaat tggctgatgg
    39601 tgatatagta actctcatca aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca
    39661 agggacgcgc gtgaaaaata tccgcatcgt agaaggcgac cacaatatcg actgtaagat
    39721 tgatggtttt ggtgccatga aacttaaatc agagtttgtg aggaagattt aagcatgtca
    39781 aaacactata aacttgtatt ttatagccgt atcttcttgt ttctagcggc ttttacggga
    39841 gtttatcttg aaattactag gcatggtggt tttgggatgc ttctctatta cacggttctg
    39901 tccaacctct tggtaactat ttttaccctt tatcttctaa aggttatgag ccgtgtaggt
    39961 gaaaattggc aaaggccaag tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg
    40021 attacctgtg tgatttacca tttcctcttg gcgcccattg cgactaattt ctatacccta
    40081 gaaaatttcc tttgccacta tatcgttccc atctggtttt tagcggatac cctctttttt
    40141 gacaaacagg gtcaatacaa gatttgggat ccagcagtgt ggaccatttt accctttctg
    40201 tatatgatgt ttgctctttt taatggcttg gttctaaaac tcaatattcc aaatgccaag
    40261 gataatcctt tcccttactt ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag
    40321 tggtgtctga ttatctttgt tgcctatatg gtagcaggat ttattttcta ctttatcaag
    40381 caaatcaaga gaaagtcatc ctaatactct tcgaaaatct cttcaaacca cgtcagtttc
    40441 catctgcaac ctcaaaacac tgttttgaac aacctgcggc tagcttccta gtttgctctt
    40501 tgattttcat tgagtataag atacaaggga ttcattttcg aatttaagaa ggagtctaca
    40561 aaccaatgag gcttcttctt ttcttgctta tttgataact atcaaaaaag tagaagatta
    40621 agagaaatat agaaagagat ttcatgaaac aatttttaga acgggccagc attttggctc
    40681 tctccctcgt tttgattacc tccttttcca tttcgagtgc cctaccagcc atgtttgact
    40741 attatcaggg ttattctaag gaacaaattg agctcttggt gagcttgcct tcctttggaa
    40801 tcatgatgat gttactgcta aatggtttct tagaaaaaat atttcctgag cgcttacaga
    40861 ttagtttggg cttgctgatt ttatcattga gcggtacagc tcccttctgg taccaagcct
    40921 atccctttgt ctttggaaca cggcttctct ttggtttggg tcttgggatg atcaatgcca
    40981 aggccatttc tattatcagt gaacgctatc aaggaaaaag gcgaattcag atgttagggc
    41041 tacgcgcttc tgcagaggtc gttggagctt ctctcattac cttggccgtc ggtcagttgt
    41101 tggcctttgg ttggacagct atctttctag cctatagtgc tggatttttg gtgctgcccc
    41161 tttatctgct ctttgtccct tatggaaaat caaagaaaga agtcaagaaa agagcgaaga
    41221 aagcaagtcg tttaactcga gaaatgaaag gcttgatttt taccttagct atcgaagcgg
    41281 cagttgtagt ttgtaccaat acagctatta ccatccgtat tccaagtttg atggtggaaa
    41341 gaggattggg ggatgcccag ttatctagtt ttgttcttag tatcatgcag ttgatcggga
    41401 ttgtggctgg ggtgagtttt tctttcttga tttctatctt taaagagaaa ctgctcctct
    41461 ggtctggtat tacctttggc ttggggcaaa tcgtgattgc cttgtcttca tccttgtggg
    41521 tggtagtagc aggaagtgtt ctggctggat ttgcctatag tgtagtcttg acgacggtct
    41581 ttcaacttgt ctctgaacga attccagcta aactcctcaa tcaagcaact tcatttgctg
    41641 tattaggctg tagtttcgga gcctttacga ccccatttgt tctaggtgca attggcttac
    41701 taactcacaa tgggatgttg gtctttagta tcttaggagg ttggttgatt gtaatctcta
    41761 tctttgtcat gtacctactt cagaagagag cttaggattg attcctaagt ttttcttttg
    41821 atactcaatg aaaatcaaag agcgtagttg attgagtttg gaatagtacg ctgtagctgc
    41881 taaaatattt ctagaaatta atttgacttt cctaatagag ttgttcatat cttatttcaa
    41941 tctactatag aaagctagcc gcaggttgct caaaatagtg ttttgaggtt gcagatggaa
    42001 actgacgtag tttgaagaga ttttcgaaga gtatgagatt tttataccca tacaatattt
    42061 gttttaggtc cttgtttaca gactaatttc ttgataaaat agaggttatg acgagatata
    42121 aagcaactat ttcctatgat ggttatgcct ttgctggctt tcagcgccag cctcatgcgc
    42181 gtagcgttca ggaagaaatt gaaaaaacct tgaccagatt aaataaaggg caaaccatta
    42241 ctgttcacgg tgctggtagg acagatagtg gggttcatgc cctgggacag gtcattcatt
    42301 ttgacctgcc ttatcagatg gatgaggaga aactccgttt tgccttggat acccagtctc
    42361 ctgaagatat tgatgtgatt tcgattgagc ttgtggcaga tgattttcat tgccgttatg
    42421 ccaaacatag caagacctat gagtttattg tggatagagg acgtcccaaa aatcctatgc
    42481 gccgtcacta tgccacccac tttccctacc cactcgatgt ggaacgaatg cagattgcaa
    42541 tcaaaaagct agagggaacc catgatttta ccggttttac agcctctggg actagtgtag
    42601 aggataaggt tcgcaccatc acagaagcta gtttaatagt cgatgagaca ggacaatttt
    42661 tgacctttac cttttcagga aatggtttct tgtataaaca gattcgcaat atggtgggga
    42721 ctcttctcaa aatcggtaac aaccgcatgc cagtagagca gattgctctc atcttggaga
    42781 agaaggacag gcaacttgca ggtcccactg cagcaccaaa tggtttgtat ttaaaggaga
    42841 ttcgttatga agaataatcg tattttagca ctttctggaa atgatatttt tagtggtggt
    42901 ggactgtcag ctgatttggc tacctatacc ttgaacggct tgcatgggtt tgtagcagtg
    42961 acttgtttga cagccttgac agaaaaagga tttgaagtct ttccaactga tgataccatt
    43021 tttcaacatg aattagatag cttgcgtgat gtggaatttg ggggaattaa gattggtctt
    43081 ctccctactg tcagtgtggc tgagaaggcc ttggacttta tcaaacaacg cccaggagta
    43141 cctgtggtgt tggatcctgt cttggtctgc aaggaaacgc atgatgtagc tgtcagtgag
    43201 ctctgccaag agttgattcg cttcttccct tatgtcagtg tgattacgcc taatctccca
    43261 gaagcagaat tattatccgg tcaggaaatt aaaaccttgg aagacatgaa aactgcagcg
    43321 cagaaattgc atgatttagg agcgccagca gtcattatca agggaggcaa tcgtcttagt
    43381 caggacaagg ctgtggatgt cttttatgat ggacagacct ttactatcct agaaaatcca
    43441 gttatccaag gccaaaatgc tggtgcaggt tgtacctttg cctctagcat tgccagtcac
    43501 ctggttaaag gtgataaact tttgccagca gtagaaagct ctaaggcttt cgtttatcgt
    43561 gctattgcac aagcagatca gtatggagta agacaatatg aagcaaacaa aaacaactaa
    43621 aatcgccctt gtatccctat taaccgccct ttctgtggtt ctaggttatt tcttaaaatt
    43681 cccaacacct acaggaattc taactctttt agatgctggt gtcttctttg cggcctttta
    43741 ctttggtagt cgtgaaggag cggtagtcgg aggactagca agtttcttga ttgacctctt
    43801 atcaggctac cctcagtgga tgttctttag cttggtcaac catggcttgc agggattttt
    43861 cgcaggattt aaaggaaaaa gtcagtggtt aggccttatt ttagcaacta ttgccatggt
    43921 aggaggctac gccttgggtt ctactttgat gaatggctgg gcagcagccc tcccagaaat
    43981 tctaccgaat tttatgcaaa atatggtagg gatgattgta ggatttattc ttagtcaaag
    44041 tatcaagaag attaagtaat actcttcgaa aatctcttca aaccacgtca gcttccatct
    44101 gcaacctcaa aacactgttt tgagcagcct gaggctagct ttctagtttg cactttgatt
    44161 ttcattgagt ataaagaggt tgagtaaaaa gtctttcaaa taagaaaaac gcattatatc
    44221 aagtcttgac tgaactgcac cccaaaagtt agacagaaaa aatctaactt ttggggtgtt
    44281 tttattatga aa
//
LOCUS       DAVLIK010000015        41817 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLIK010000015 DAVLIK010000000
VERSION     DAVLIK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.015"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..401
                     /locus_tag="VXE87_000862"
     CDS             <1..401
                     /locus_tag="VXE87_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0842438.1"
                     /translation="KNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSGFTDADYQKQ
                     GAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPELADAMLAAKT
                     TGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            402..815
                     /locus_tag="VXE87_000863"
     CDS             402..815
                     /locus_tag="VXE87_000863"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV0842439.1"
                     /translation="MGAHFLTKQAGGSGVLLGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            761..1087
                     /locus_tag="VXE87_000864"
     CDS             761..1087
                     /locus_tag="VXE87_000864"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842440.1"
                     /translation="MVDIAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(1454..1714)
                     /locus_tag="VXE87_000865"
                     /pseudo
     CDS             complement(1454..1714)
                     /locus_tag="VXE87_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(1717..2217)
                     /locus_tag="VXE87_000866"
     CDS             complement(1717..2217)
                     /locus_tag="VXE87_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0842441.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            2253..2432
                     /locus_tag="VXE87_000867"
     CDS             2253..2432
                     /locus_tag="VXE87_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842442.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(2410..3378)
                     /locus_tag="VXE87_000868"
     CDS             complement(2410..3378)
                     /locus_tag="VXE87_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0842443.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(3464..3679)
                     /locus_tag="VXE87_000869"
     CDS             complement(3464..3679)
                     /locus_tag="VXE87_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0842444.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDAIWQEYLEH"
     gene            complement(3688..4542)
                     /gene="cvfB"
                     /locus_tag="VXE87_000870"
     CDS             complement(3688..4542)
                     /gene="cvfB"
                     /locus_tag="VXE87_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0842445.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(4602..5159)
                     /gene="frr"
                     /locus_tag="VXE87_000871"
     CDS             complement(4602..5159)
                     /gene="frr"
                     /locus_tag="VXE87_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0842446.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKREKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(5168..5905)
                     /locus_tag="VXE87_000872"
     CDS             complement(5168..5905)
                     /locus_tag="VXE87_000872"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0842447.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(5989..7323)
                     /gene="trmFO"
                     /locus_tag="VXE87_000873"
     CDS             complement(5989..7323)
                     /gene="trmFO"
                     /locus_tag="VXE87_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0842448.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(7568..7808)
                     /locus_tag="VXE87_000874"
                     /pseudo
     CDS             complement(7568..7808)
                     /locus_tag="VXE87_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
     gene            7818..8622
                     /locus_tag="VXE87_000875"
     CDS             join(7818..8186,8188..8622)
                     /locus_tag="VXE87_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0842449.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLHYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATKVKINRPKKELANDSGKKKCHAMKSQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPHKSSKLKPLIAEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(8611..9258)
                     /locus_tag="VXE87_000876"
     CDS             complement(8611..9258)
                     /locus_tag="VXE87_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV0842450.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(9367..9885)
                     /locus_tag="VXE87_000877"
     CDS             complement(9367..9885)
                     /locus_tag="VXE87_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0842451.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(10112..10981)
                     /gene="rsmI"
                     /locus_tag="VXE87_000878"
     CDS             complement(10112..10981)
                     /gene="rsmI"
                     /locus_tag="VXE87_000878"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0842452.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(10984..11301)
                     /gene="yabA"
                     /locus_tag="VXE87_000879"
     CDS             complement(10984..11301)
                     /gene="yabA"
                     /locus_tag="VXE87_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0842453.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(11341..12231)
                     /locus_tag="VXE87_000880"
     CDS             complement(11341..12231)
                     /locus_tag="VXE87_000880"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0842454.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLTKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(12228..12866)
                     /locus_tag="VXE87_000881"
     CDS             complement(12228..12866)
                     /locus_tag="VXE87_000881"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0842455.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(13088..13885)
                     /gene="proC"
                     /locus_tag="VXE87_000882"
     CDS             complement(13088..13885)
                     /gene="proC"
                     /locus_tag="VXE87_000882"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0842456.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(13889..15151)
                     /locus_tag="VXE87_000883"
     CDS             complement(13889..15151)
                     /locus_tag="VXE87_000883"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0842457.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(15161..16291)
                     /locus_tag="VXE87_000884"
     CDS             complement(15161..16291)
                     /locus_tag="VXE87_000884"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0842458.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(16371..18254)
                     /gene="cbpE"
                     /locus_tag="VXE87_000885"
                     /gene_synonym="pce"
     CDS             complement(16371..18254)
                     /gene="cbpE"
                     /locus_tag="VXE87_000885"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0842459.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWRQGINTTYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(18257..19144)
                     /locus_tag="VXE87_000886"
     CDS             complement(18257..19144)
                     /locus_tag="VXE87_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0842460.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(19134..19595)
                     /locus_tag="VXE87_000887"
     CDS             complement(19134..19595)
                     /locus_tag="VXE87_000887"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0842461.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(19592..20500)
                     /locus_tag="VXE87_000888"
     CDS             complement(19592..20500)
                     /locus_tag="VXE87_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0842462.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKDELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            20493..20690
                     /locus_tag="VXE87_000889"
                     /pseudo
     CDS             20493..20690
                     /locus_tag="VXE87_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(20742..21413)
                     /locus_tag="VXE87_000890"
     CDS             complement(20742..21413)
                     /locus_tag="VXE87_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0842463.1"
                     /translation="MKKRAIQILLVLSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(21467..21688)
                     /locus_tag="VXE87_000891"
     CDS             complement(21467..21688)
                     /locus_tag="VXE87_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV0842464.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLL
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            21960..22769
                     /locus_tag="VXE87_000892"
     CDS             21960..22769
                     /locus_tag="VXE87_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0842465.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(22950..23825)
                     /gene="aguB"
                     /locus_tag="VXE87_000893"
     CDS             complement(22950..23825)
                     /gene="aguB"
                     /locus_tag="VXE87_000893"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0842466.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELFFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(23835..24920)
                     /gene="aguA"
                     /locus_tag="VXE87_000894"
     CDS             complement(23835..24920)
                     /gene="aguA"
                     /locus_tag="VXE87_000894"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0842467.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(24917..26044)
                     /gene="nspC"
                     /locus_tag="VXE87_000895"
     CDS             complement(24917..26044)
                     /gene="nspC"
                     /locus_tag="VXE87_000895"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0842468.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKEVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(26044..27303)
                     /locus_tag="VXE87_000896"
     CDS             complement(26044..27303)
                     /locus_tag="VXE87_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0842469.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(27300..28160)
                     /gene="speE"
                     /locus_tag="VXE87_000897"
     CDS             complement(27300..28160)
                     /gene="speE"
                     /locus_tag="VXE87_000897"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0842470.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            28541..29130
                     /locus_tag="VXE87_000898"
                     /pseudo
     CDS             28541..29130
                     /locus_tag="VXE87_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(29096..30571)
                     /locus_tag="VXE87_000899"
     CDS             complement(29096..30571)
                     /locus_tag="VXE87_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0842471.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            31278..32273
                     /locus_tag="VXE87_000900"
     CDS             31278..32273
                     /locus_tag="VXE87_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0842472.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            32299..32942
                     /locus_tag="VXE87_000901"
                     /pseudo
     CDS             32299..32942
                     /locus_tag="VXE87_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
     gene            complement(32984..34972)
                     /locus_tag="VXE87_000902"
     CDS             complement(32984..34972)
                     /locus_tag="VXE87_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842473.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVIAVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSDIYNQFYGGMNVSISEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(34974..35732)
                     /locus_tag="VXE87_000903"
     CDS             complement(34974..35732)
                     /locus_tag="VXE87_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842474.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            36160..36351
                     /locus_tag="VXE87_000904"
     CDS             36160..36351
                     /locus_tag="VXE87_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842475.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(36705..36977)
                     /locus_tag="VXE87_000905"
     CDS             complement(36705..36977)
                     /locus_tag="VXE87_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0842476.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(37036..37485)
                     /locus_tag="VXE87_000906"
     CDS             complement(37036..37485)
                     /locus_tag="VXE87_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0842477.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            complement(37472..39601)
                     /locus_tag="VXE87_000907"
     CDS             complement(37472..39601)
                     /locus_tag="VXE87_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0842478.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFVTRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            39645..39728
                     /locus_tag="VXE87_000908"
                     /pseudo
     CDS             39645..39728
                     /locus_tag="VXE87_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            40058..40963
                     /locus_tag="VXE87_000909"
     CDS             40058..40963
                     /locus_tag="VXE87_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0842479.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            40960..41775
                     /locus_tag="VXE87_000910"
     CDS             40960..41775
                     /locus_tag="VXE87_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0842480.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
BASE COUNT        12204 a         9354 c         7773 g        12486 t
ORIGIN      
        1 ttaaaaataa cgaaaaccgt gtcgccctca cacctgcagg tgttcatagc ttagttagtc
       61 gtggtcatcg tgtccttatc gaaacaaatg ctggtctcgg ttctggcttt actgatgctg
      121 actatcaaaa gcaaggagct gagattgtcg ctactgctgg tgaagcttgg gcagcagagt
      181 tggttgtgaa agtaaaagaa cctttaagtt ctgaatacgg ttacttgcgc gacgatcttc
      241 ttctcttcac ctacttgcac atggccgctg ctccagaatt agcagatgct atgttagcag
      301 caaaaacaac aggaattgcc tatgaaactg ttcgtgacaa tcaaggacaa ctaccgctcc
      361 tcgttcctat gagtgaggtt gcaggtcgta tggctgttta aatcggagct cacttcctta
      421 ctaagcaagc tggtggctct ggtgttctac ttggtggtgt accaggtgtt ccaaaaggaa
      481 aagtaactat catcggtgat ggtgtcgtcg gtacacatgc tgcccgcatc gcccttggtc
      541 ttggtgctca agtgactatt ttagatatta gtgccaagcg tctctcagtt ctagaagaag
      601 tctttggaag tcaaattcaa actcttatgt ctaattcatt caacattgaa gcaagtgtga
      661 gagatgctga tgtggtgatt ggagccattc tcatccctgg tgcaaaagca ccggaattgg
      721 tgacagatga gatggtcaaa caaatgcgtc caggctctgt atcgttgaca ttgctgttga
      781 ccaaggtggc cttatcgaaa cagctgaccg tgtgacaacg cacgatgaac ccgtctatga
      841 aaaacacggt gttctccact atgccgttgc caatatccct ggtgcggttg cccgcacttc
      901 aaccatcgcc ctaaccaatg tcactcttcc ttatatcgaa gctttggctg gcaaaggatt
      961 cgcacaagca atctctgaag atgaaggctt gcgtcaaggt gtgaccactt atcaaggtta
     1021 cttgactagc ctaccagttg ctcaaggact taatcgtgac tacactgata tcaatgattt
     1081 agtataaatt ttgaaaagaa aagggtgact tcgcaagtcc tacccactgt gctttgtgtc
     1141 atcagctatt acatcgttgg tttattgtac tgtatacttt gcaactggag actttcgttc
     1201 cagactcaat tgtgcataag aaactctaaa ttgaataaag tcaacagagt ttcgcccaac
     1261 cacttcgtct tgtaatgaca attatataaa ccaaaggaag ctgagctctt tagtcccagc
     1321 ttctttttat atataaaatt ttacccgtgc aaagacaggg ccttagcaga cttctttttt
     1381 acttcgttca cccttgcttt ttctttttag gtttgggcgt tggcagttgg ttatacatag
     1441 ctaaaatcag gtcttataga aacatcttat tatcaagttc ttccactcaa atcatttctt
     1501 tggcaccttt gtatggaaac tcaaaagaag attggtcaat cttatctaag actgcttgca
     1561 cgggtttaac taaaaagcga tcgtcataaa tgccgccaat aatcttgccg cggaagtaaa
     1621 gaatatactc ccccatcatg gaacggtaag tcacatcatc taatcctgat aattgttcca
     1681 aaacaaattc caaatagttc ttacttgatg ccatttctaa tcttctaggc tctgttcagc
     1741 gataacaacc gtatagagtt cttgcttaac ctcgcatcca attgatttaa agccctgctt
     1801 ttcccaaaaa tgctgagatt gcggatttcc cttaacataa gccaaacgtg cctttcgaaa
     1861 gttcttagca aaataagcta gtgcttctgt cacaatatga ctaccaatcc cttttctctg
     1921 ataggcttga tcaaccataa acaaaccaat aaaaacagtc tcctcatcag gatatgcata
     1981 gacaaaatcc ataacagcca caaggtcaga tccattccaa aatccaacaa aaaacttatc
     2041 agccttagct ttaccttcag gtagacaaag catgtcctct tttacagttg caaaatttgg
     2101 ctctggtgga caatgctgaa aatacagagg attactttca tataaagata aaatacttgg
     2161 aatatccttt tcagttagta tcctacaact gtaatactta gatagttggt caatcatctt
     2221 ttcaaattcc tactttcttg tgccctgtga ttatgacaca ggaagatgca ctgatcgtca
     2281 tcagccacat aaaagttctt tccatcgtgc ctaatcgttg tctcagacct ttggataaaa
     2341 cctttagcct atacaactgg attttcctct ctcaaaagta tattcttttg caggcgaact
     2401 tcctcaaaat cagtcgtgtg caacttcagt agaatattca taggctcgga taatctgagc
     2461 gacaactgga tggcgaacca catccttggc tgaaaaatga acaaagtcaa tctgatggat
     2521 gttcttgagt ttctcttgag catcaatcaa accggacttg acattacgtg gcaggtcaat
     2581 ctgactgata tctccattga caatcatctt agaatgaaag cctaaacgcg tcaagaacat
     2641 cttcatctgc atgatggtcg tgttttgcgc ctcatcgaga atgacaaagg catcatccaa
     2701 ggtccggcca cgcatatagg caaggggcgc aatttcgata atttcacgct ccatgagacg
     2761 agtcgtttgg tctttcccca gaatctgata caaggcatca taaacaggtc taaggtaagg
     2821 atctaccttc tccttaagat cacccggaag aaaacctaga ctctctcctg cttccaccgc
     2881 tggacgtgtc aagataatcc gcttgacttg cccacgttta agggcagtca ctgccaaagt
     2941 aactgcaaga aaggtcttcc ccgtccctgc aggcccaatt ccaaaggtca catcatgctg
     3001 tttgacactg tccacataaa gtttttgacc taacgtttta acgcggatcg gtttcccagt
     3061 attatccttg ataatttctt cttcgtaaag ggcgacaaac ttatcaattt catcgttttt
     3121 gaccatgcta attgcagtca ccacatctgg cgtaccaacg gtcatcccac gatttaccaa
     3181 gaccatcaaa gcctgaataa cttgacgggc ttcctcacag gcagactctt ctcccaaaac
     3241 ctggacaatc tccgtacgag catgaatcac aacatcaagc tcttcttcca tcaaacgaag
     3301 atggcgttca ttggaaccaa aaagatgaaa caggtcatct ggatgactca gttgaatgtc
     3361 tattgaatgt tccttcaaat aaagaacctc tctaatcctt ttatttcttt ttattatagc
     3421 agagggatgg agaaattact agcccaaacc tagtgaataa atgctagtgt tctaagtatt
     3481 cttgccagat agcgtcaaag tctcctaggt taaaagagaa actggcatgc tcctccaaaa
     3541 agcgactgac ctcatcaaaa tcatctgtgt gttttggaaa agctgcctct tcaaaagcga
     3601 ggtctgccaa aattgctttg ggactgttac ttttaggatt gcgctcggtc atgagccaag
     3661 tgtaaaatga ttttctcata agcctcccta aatcaactct gtcccaaact ggtcctgctt
     3721 gattttacca gccttcataa gaccacctaa agctttcttg aactgacctt tagaaatgcc
     3781 aaaggttgcc ttgatgtcgt ctggagatga cttatcattt aaggtcatga aaccgccatt
     3841 actttccaaa taagtcaaaa tcatctgagc atcgttttcc aacatttcaa aggagcgtgg
     3901 tttgagggag aggttcagag tgcggtccac ttcacggaaa ccaataacgc gcgcatctaa
     3961 tacttgcccc aaacgtggct ctgcgtaacg ctcgctagga tgaataaaac caagcatatt
     4021 attttctggt aggtaaacaa aagttcctga cagcttgaga cggtaaacaa tggctggcca
     4081 gttttggttc tgcatgttgt tgtaggcagg acgagcaaga cgttggaagt cttcttgata
     4141 agccaagagg ccccagatac ggtctttctt atccacttca agacggatgt agagttggtc
     4201 gcccttctta ggccagagtt ccttgagctc agggagaata tcgagtgaca caacgatttc
     4261 cttgtcagga aggcctgtat ccacaaagac acccaagtcc ttacgaacct ctgtgacacg
     4321 tccccaacca aattggtcct gagtggcagt cacttctaag gttgtcaggc ggagtttttg
     4381 cttcatatcc gtgtatgcaa aacctttgac cgtatcccct actgtatgtt ggccttcttc
     4441 cttagcaaga gcataggttt gaccatcctt ttgcacaaag taaaaacggt cgttttcatc
     4501 gatgatcagt ccaacgataa aacttgcaag atttgtattc atatttcctt ctttcgaata
     4561 aaactcagcc agcaatgcca actgagtttt tctgtttatt tttagacttc caaaagttct
     4621 ttctctttgt tagcagtcat gtcgtcgatg tgtttaacag catcgtctgt tactttttga
     4681 atgtcttttt caagagtctt caattcgtct tcagtgattt cttttgcttt ttctcgtttc
     4741 ttagcttcgt ccatagcatc gcgacggata ttgcggacag ccactttagc attttcgccg
     4801 accttcttca cttctttagc aaggtcacga cgagtttctt ctgtaagagc tgggataacc
     4861 aagcgaatca cagaaccgtc attagccggt gtgataccaa gatcagaagc gttcaaggca
     4921 cgttcgatgt ctttcaatga agacttgtca aatggtgtta ccaacaaaac acgcgcttct
     4981 ggaatcgtaa ttgaagcgat ttggttaaga ggagtttcga ctccatagta ttctacatgt
     5041 acacggtcaa gcaagcttgc attggcacga ccagcacgga taccaccaaa ttcacgagca
     5101 agtgattggt gagactgggt cattctctct ttagcttttt caataattgc gttagccata
     5161 ttctttctta ttccttttct tcgatattat ttgaaactgt tgttccgata ttttcaccaa
     5221 atacgacacg tttgatgttt cctggttggt tcatgttgaa gacaaccaag tcaatgtcgt
     5281 tgtccattga gagggttgag gctgttgagt ccatgatacg aagacctttg ttgataacat
     5341 cacggtgggt caattcttca aacttaacgg ctgtcttgtc cttcttagga tcggcattgt
     5401 acacaccatc gacgccattt ttagccatga ggatggcatc tgcttcgatt tcagctgcgc
     5461 gaagagccgc tgttgtatct gtcgagaagt atggtgaacc aattccagca ccaaagataa
     5521 cgatacggcc tttttcaagg tgacgaaggg cacgtccacg gacataaggc tctgccactt
     5581 gttgcatggc aatagctgtt tgtacacgcg tatcaacccc aacttgttgc aatgaatctg
     5641 ccatcacaag agcattcata acagtcccaa gcattccagt gtaatctgcc tgaacacggt
     5701 ccatacctgc ttctgctgca ggttctccac gccagagatt tcctccacca ataacaaggg
     5761 caatttcgat acctaagcta tgaacttctt gaatctcttt tgcgattgtt tgaactgttt
     5821 ggatatcaat ccctacgcca cgttcaccgg caagggcttc acctgataac ttgattaaaa
     5881 tacgtttata cttgggattc gccattttca ctctccttct ttcatcctac ctattttatc
     5941 acaatttcta agatttttat agtatcatga gcaattcttt caaaaaaatt agacagtcaa
     6001 aaattcctct aagtcggcaa gggcacgctc tgcaattttt tcataacgag ccttcttatc
     6061 acggatacgc tcgccttcca actccttgat gatcccaaaa ttgacattca ttggttggaa
     6121 atgtttgctg tcggcatggg taatgtaatg agctaagctt ccaatcgctg tcgtctcggg
     6181 gaaaataacc tcgctttctt ccttgaagag acgagctgcg ttaattcccg caactaagcc
     6241 cgaagccgcc gactcaacat agccttccac ccccgtcatc tgaccagcaa agaagagatt
     6301 tggttgtttc ttagaacggt aagtctgctc aagaagattt ggtgaatcca tgtaagaatt
     6361 gcgatgcatc acaccataac ggacaaactc cgcattttca agacccggaa tcatttggaa
     6421 gacacgcttt tgttctcccc atttgaggtg ggtctggaaa ccaacaatat tgtagaggct
     6481 accagctgca ttatcctgac gaagttgcac aaccgcataa ggtgttttaa attctccatc
     6541 acgaggtcct gtatagtcgt ctgggtactc aagaccgact ggcttcatag ggccataaag
     6601 catagtttta atgccacgtt tggccatgac ttcgataggc atacatcctt caaagtactt
     6661 ttctttttca aaagaattaa gcggtgcttc ttctgcattg accaaagctt catggaaatc
     6721 cataaattct tgcttggtca taggggcatt gaggtaggcc gcttctccct tatcataacg
     6781 tgatttgagg tagaccttgc tcatatcgat agtgttgaca tcgataatag gcgctgccgc
     6841 atcgtagaaa taaaaaccag caccgtcatt aagagcatga atcttttcag ctaaggcatc
     6901 acttgtcaaa ggaccagtag cgataaccgt aataacatct gtcggcaatt ctgtaatttc
     6961 atcacgaacc acttcaatca aggggtggtt ggcaactttt tcggtcacca tttgagagaa
     7021 accatcacgg tccactgcaa gggcaccacc tgcaggaaca cgtgtagcct cagcagattc
     7081 caagataaca gaacccaagc gacgcatttc ttccttgaga agaccaactg catttgtcaa
     7141 agcatcccca cgcaaagaat tggaacaaac caactcagca aaattgtctg ttttatgctg
     7201 gggtgtagac ttgacaccac gcatttcata tagtttaact ggaataccac gctctgcgat
     7261 ttggtaagct gcttcagaac ctgccaaacc agcaccgata acattgatat aagattgaga
     7321 cacgacacta atacctcttt gggagtgtga agttaagatt cacattgaaa aagccaatca
     7381 gacttacgag ctttcgagtt tcttggctca ggctgaaaaa gtccacagga ctttttcact
     7441 cccacaaatc tttctatttt ttcttctact agtataacaa aaaaagggaa gaaggcaaac
     7501 ttccctgttt agtcattttc ttgatgtaaa gagatagtga gtattccagt taagaatcaa
     7561 ttatatgcta ctctataaaa tcttttccac ataacggatc gatagggact gttattctat
     7621 ctcttgctat aaccgtatta tctaaaacag cataacattc aacatagtga tctcctttaa
     7681 actgtgaatc ttcgtgatat tttattttta cctgaaaaaa tagcaccacg ctcacaattt
     7741 cttctaatag cctcagcttc aatatttctt actttccaat agacttcctg cgaaacaaaa
     7801 tatggtatag tagttctatg aatgatgaag caagtaaaca actaactgat gcacgattta
     7861 agcgtcttgt tggtgttcag cgtaccactt ttgaagagat gttagctgta ttaaaaacag
     7921 cttatcaact taaacacgca aaaggtggac gaaaacctaa attaagccta gaagaccttc
     7981 ttatggccac tcttcactat gtgcgagaat atcgaactta tgaagaaatt gcggctgatt
     8041 ttggtatcca cgaaagcaac ttactccgtc ggagccaatg ggttgaagta actcttgttc
     8101 aaagtggttt tacgatttca agaactcctc tcagttctga ggacacggta atgattgatg
     8161 cgacgaaagt aaaaatcaat cgccctaaaa aaagaattag cgaatgattc tggtaaaaag
     8221 aaatgccacg ctatgaagtc tcaggcgatt gtcacaagtc aagggagaat tgtttctttg
     8281 gatatcactg tgaactattg tcatgatatg aagttgttca aaatgagtcg cagaaatatc
     8341 ggacaagctg gtaaaatctt ggctgacagt ggttatcaag ggctcatgaa gatatatcct
     8401 caagcacaaa ctccacataa atccagcaaa ctcaagccgc taatagctga agataaagcc
     8461 tataaccatg cgctatctaa ggagagaagc aaggttgaga acatctttgc caaagtaaaa
     8521 acgtttaaaa tgttttcaac aacctatcga aatcatcgta aacgcttcgg attacgaatg
     8581 aatttgagtg ctggtattat caatcatgaa ctaggattct agttttgcag gaagtctaat
     8641 gtaattctca agctgtgagt tcattatgat ttgtaaatcc gatatatctt cagcagctaa
     8701 aaacacattt tgaaatgttc caagtccgtt ttcaccaaaa ctatattctc tcttactata
     8761 cttactctta ttattctcta tatagttaga gtcaaggttc ttaacctctt gaagttcatt
     8821 ttctttactt ctgaggttaa aatcttttac ttctgaagtt aagttttttg acttctgtaa
     8881 gtcattttct tttacctgaa atatactcat aaagtcttta acataaatga tattcggctt
     8941 accaagtcca agccttactc tttcgatcag tcctattcct ttttttacat caagctcatc
     9001 taatgttttt atggcagttg gctttgagat atttcttctt ttcataattt cttcgacagt
     9061 aaaatagata aatactctgc cttccttgtc tatccagtta ttcttaaatg acattcctgt
     9121 ctgtttaaga agtatggaat aaaggataat tgcttctgct gataagcccc gaaattcttc
     9181 tctatcaact aatatctccg gtacttttaa gaagttaaat ctttccgctt ctctgttata
     9241 aaaatattca aagtccatgc aagatcacct cccttcttaa aaatttgcaa agaaaaagac
     9301 gatagttttt cttctatcgc ctttggtaac catttttatg aaatttttta aagttaaaaa
     9361 tataatttat aatactatct tcttccattt tctgatttta gttctgaaag ttccaaaagg
     9421 tgcaaccgta tttacatgaa taaacttata cacttcccaa gtcgctgttt tagtcgcttc
     9481 atcagcccac tttctcatat gcggttcaaa taattcttcc tcactcaacg aatcaatcat
     9541 tgcagagata gaattaatat tttcatttaa ttttgctttc aactcttgca gagataaatg
     9601 agcgtaggta tctgtgaacc actgatataa ctcaccaagt tgattccatt taaatttatc
     9661 cgatggtgtt tttacttgaa gcccctttct ttcatcttct tcccatttaa gaaccaagtt
     9721 ggtccaacca acctgataag caaggttttc tgctggagtt ctgtcaactt catcagctct
     9781 cttatctttt aaattttctg gaatattatc aaattctaaa atatatttct caaatgtttt
     9841 ctctatctca gcttttagtt cttctttatt ttcgtatgtt cgcaaaaaat caccttcttt
     9901 ctgatttatc aatcctttga tttaaaatga ccttattttt ctatttatac cttctaagaa
     9961 cgctataact gctgctccaa ccatcggtat tccgtatggg cttaataaaa aacttaatac
    10021 caaagcttct ataccaagtg atacatcttt atattatcat cactaattaa gttaaacaga
    10081 aacagacaga attattacat cctgtctccc tttattgttt ttcttcccag tcgtggtagg
    10141 cagcgtagag ttgactctta ttccactggt aaatcttagc tacttcctta atagcttgat
    10201 ttttcttcat accttgctgg atacgagctt ggatttctaa gaacaagtct tcctcgtctt
    10261 tttcttccac acctttgctg gcaccttcaa caatcagaag acattcaccc ttgagagacg
    10321 tttcagagat gctttccagc aattcagaaa ttgtacctct ttggtattct tcatagattt
    10381 tggtcaattc cctgaccaag acaacggagc ggtcaccgta gacttctaac atattttcca
    10441 acgtgtctgc tacacgatga ggtgattcat aaaaaatctg tgtttcagga taatcttttt
    10501 tcgagtcaaa aaattgcttc tgctggcctg attttctcgg taaaaagccg taaaagatat
    10561 gtggctgcgg cgctaaacca ctggcaatca aggcagaaat tcctgcagag gcacctggaa
    10621 ctgtaacaac tgcaatttct tcctcaatag ctgccttaac taaatcatga ccagggtctg
    10681 aaatgctagg caaaccggca tcagagacct gagcaatact ttgccctgct ttcaagaaac
    10741 caatcaaatc aggaattttt tccttggcat tgtgctcatg aaaactgatc tgcttggtgg
    10801 aaatgtcaaa atgcttgagc aaaagccctg tattgcgcgt atcctcagca gcaatccaat
    10861 ctacttcttt caaggtctgg atagcacgaa aagtcatatc atctagattg ccaatcggcg
    10921 ttgccactag atacagcttg ccatagggag actgcccctt aaaacttttt tgaatttgca
    10981 tgcctactcc ctgtataaca actcatcaca gaacatacat tcttcgtcct gctctcgacg
    11041 ttgtccataa aaatcattac atacgtgaaa tccatcacgg taaatacgac ggacactttc
    11101 gcgaacatgc ttggccttga cgggagcgtc tgcttccacc tcacccaagc gttctcgcaa
    11161 cttactattt tccaagcgaa gagctgtatt ttcttctacc aagctcttga gatttttctt
    11221 gatggcttcc acatcggcta aggttaccaa taattgttgg gaaaaatcat ccagcgcgtc
    11281 aaataattct tttttgtcca taaaacagcc ctttcctttc tttatcattc atttttgagt
    11341 ttatatttct ttcaagacca gatattccat ggcattttga aagctgacat tagcttgcca
    11401 catttttcta gcttctagta aatcttgtag aatcactctt actcttacct gcaagaggtc
    11461 ctgcccacag agaacttcaa gaatccgtaa aacctgatcc tgtttttcct tatcatctgc
    11521 caagttggct aatttggcaa cctgtagata actttctttt ttcttagcta ctaaccaagt
    11581 cagcaggcgt tcactttcat cgaccaaggt ccaaaaactt gcctgattag ccaacttttc
    11641 tgcttcagct cgcgattgac taaacttagt taaaagagtc gcttttttct taacaagtcc
    11701 catttgttct aagagtaaga tgagtttttc ttcttgcttt ttaaagtgga agatctgagt
    11761 ccgacttcgg attgtcggta acatcttttc ctcatcgcta gtcaagaaga aaatataaac
    11821 ttcactctgg ggttcttcga tgaccttgag cagagaattg gctgcgttgg gatgcatttt
    11881 atccgcttgc tcgatgataa agacctgttg ctggctttca atccctgctt gagaaaactg
    11941 tcccaccaat tcccgaatgc gttctgtctt gatgacctga ttgactggct taatcaaggt
    12001 gacatctgga aactcttcct gttcaatcag cttgcaactt cggcatttct cacatggtaa
    12061 gacgccaact ttatccgtac aaaagaggct cttagctaaa aattgcgcca tttccaagct
    12121 tccaaagaaa cctgaaaaga gataggcgtg attgagctgg tcttgttcta agatacggac
    12181 aaaacggtca aactgagctg gttgccaagc ctttagttga tcttgtttca tttggccaag
    12241 cccattccgt caaacaagac agccttggta gtttccacaa cttgctccaa agggagacta
    12301 gcatcaatct tgacaatgcg atttccttct ttttccagga gagaaaggta gccttgacga
    12361 acttttttat gcaagtccaa cccttccaaa tccaaacgat taacctcgcg gtcactatta
    12421 gcagcaatac gagccagccc ttcttccacc tcgatgtcaa aatagagtgt caaatcgggt
    12481 ttgaggccat ctgtcgcaaa ctgattgagc cagtcaatgg cttcaatatc taagccacga
    12541 ccaaatccct gataggcaac agaactatcg ataaaacgat ccatgatgac caacttgcca
    12601 gcttcaaggg ctggaagaac tttttccacc aaatgctgtc tgcgactggc aatatagaga
    12661 agtagctctg ttttagcatc catctgagta tgacttggat ccaaaatcac ttcccgaatc
    12721 ttctccccaa tcaagactcc gccaggttca cgggtcgtca gcacctttac tcctttttcc
    12781 tctaaaattg gtagcagagc ctctaaaaca ctggtcttgc ctgctccctc tggtccctca
    12841 agagagacta aaaatccttt tgacatgtct aactcatttc ttttttacta cttctattct
    12901 atcaaaaaaa taggggtttg tgacaatctt tttgtgtctt ctcatttcat actcaatgaa
    12961 aatcaaagag caaactagga agctagccgc aggctgtact tgagtacggc aaggtgaagc
    13021 tgacgcagtt tgaatttgat tttcgaagag tatcaaccac cataaaagag gcagataaaa
    13081 ctacctctta tttacctagt tcttgtgttc gtttgtaggc ttgatgaact gcatccatga
    13141 ctgttcctcg gaaagcatgc gcttctaggc ttgctacacc agcgatagtc gaaccgcctg
    13201 ggctacagac ttggtctttc aatactccag gatgttgctg gctttctagg accaattgcc
    13261 cagctcctac cacagtttgg gctgccattt tcaaggctgt ttctcgtggt aatcccgtct
    13321 gaacacctgc atctgccaag gcctcaataa agagatagac aaaggctggt ccacaacctg
    13381 caagacctgt cgctgcattg attaagcttt ctcctaattc aaccaagaga ccagccttgg
    13441 ctaaaagctg acaaaagagc tcactgtcct cagccctgca attaggagac aaggcataac
    13501 taatcactcc ttgcccgata gaagcagggg tattaggcat catacgaata attcggtgtt
    13561 ggcttgggat aagacttgct agtttttcta aggtcaatcc agctgccatc gaaatcaaaa
    13621 gaagactttc tcttttttca aggatggtct ggtattgaga aagcagttca gaaaactgag
    13681 caggcttaac acctagaaaa atcacatctg cttcttcgaa tatttcttca ttgttagaag
    13741 tctgaccacc gaagttagcg atgaaagcat ccaccttgac ttgactacga ttggcaagga
    13801 gaatctcatc tgacggtcta gcctgcaaga cagacttggc taaactagca cccatattcc
    13861 ccaaaccgat aaatccaatc ttcatccctt actcccttat ctgtccatca ccagtgacca
    13921 catacttgta gctagtcaat tccttcaagc ccatgggacc acgcgcgtgc aatttctgag
    13981 tagaaatccc catttcacaa ccaagaccaa attgtcctcc atctgtgaaa cgagttgagg
    14041 cattaacata caccgctgca gagtccactt gatctgtaaa gtatgctgca gcttcagcat
    14101 tttccgtcac aatagcatcc gaatgatggg tgctgtggga ttcaatgtgc gcaaccgctt
    14161 cttctaaact gctcacaacc ttaacagcaa ggacatagtc taaaaactcg gtgtcaaagt
    14221 cttgggtctc agctgcttga cctgaaacaa actggcttgc tttgctatcc aagcggaatt
    14281 gaattggttc cagtccagct tccttacgct ctgcaaccag catttgatcc aagcgaggaa
    14341 ggatgcttgc tgccttgttt tcatgaacca gcagaacctc catggcatta caaacagaag
    14401 gacgactggt tttagcattg ttgatgatag acagcgcctt gtcttcgtct gcatccttat
    14461 ccacatagac atggacaatc ccagtccctg tctcgataac aggtacaatc gcattctcaa
    14521 ccactgcatt gatcaagcca gctcctccac gaggaatgag aaggtctaga tagcccttgg
    14581 ccttcatcat agcataacta ctttcacggc tagtatcctc caccagttga atcacatttg
    14641 gatgaatagt agtcgtctcc aagcccttct tcaaggctgt gacaatggca tgggttgttt
    14701 gataggcatc cttaccacta cgaagaacaa ccgcatttcc actcttaaga gtcaaagcag
    14761 ccgcatcaga cgtcacattt ggacggcttt catagataat accgatgaca cccatagcta
    14821 cacgtttttt tgtgataacc aaaccatttt caagctgact tgtttctaaa acttcaccga
    14881 ttggatctgg taaggcaacc acttcacgaa ttcctcttgc catcgcttct atacgatctg
    14941 catccaaata aagacgatcc aacatcacat ctgagatttt ccccttagcc gctgccatat
    15001 cgagggcatt agccgctaaa atttcctcag tagcagccac taagtgatca gccatggcta
    15061 gcaaggcttg gtttttcact tcttcactag ctgtgttaat cgatttttta acagcctgta
    15121 cctgttcaaa ttgttcttgt ctactcacca tagtttacct ctaaaattct gtaaaaagta
    15181 gttggatttc aggagtaatg gaaatccagt cgtcacggta aatcaagaca cccttggctt
    15241 tttgagaacg caacatatcc tccaaagcag atgctccaaa ttgcacgcgt ccttttccaa
    15301 gtgattttcc actttcctta tcaaatactg tcacgatatc accgtaagaa aagactcctt
    15361 ctgcttcaac gataccagat aagagaagac tctttccatg ttgagagaga gcttccgcag
    15421 cccctttatc aacccaaata gaaccttgac tctgagcata gaaggcaagc cattgtttct
    15481 gggtacgaag ccccttctct tgagcaacaa agtaagaacc atcctcggtc tcctctgccg
    15541 cctcaatcat ggaatctgat ttcaaggatg agcagatata aacaggaact cctgattccg
    15601 tcgcgatagt tgcagccttg attttggtta acataccccc agttccgttt gacgaaccag
    15661 ctccaccagc catatcaata atctcacgat tgatggtctc gattctctcc aagcgtttgg
    15721 ctcttggatc tgaattagga tttccagtat agagaccgtc cacatctgtc aagaaaacta
    15781 aaaggtctgc ttggaccatc gccgctactt gagcacttag agtgtcattg tccccaacct
    15841 tgagctcatc aataacgaca ctatcattct cattgatgat aggaattgcc ccacggttga
    15901 gcaaaaccga caaagcctga tgggcatttt tataacgacg cttatccaca aagtcatctt
    15961 gggtcagcaa gatttgtgca gaaacgattt gacgcaagag aagattggtt gtatattctt
    16021 ccaacaaaag cccctgccct accgctgctg aagcctgttt atcagcaatt ttagtcggac
    16081 gctttttaaa tcctaaggct ccaaaaccag ccgcaatggc acctgaagac accaaaatca
    16141 actcatgacc agcctcgtgc agcatagcca actgctgggt aatatccttt accttactac
    16201 gtgataaact tccatcctca tttgtcagag aagaagtacc caccttaaag acaatccgtt
    16261 tgtatttcat agtctcactc cgattattca tatttatcca ttataacatg aataacagga
    16321 aatagaaaag agttgatagg aaaaagaagg ccctaaaacc ttcttttcta ctactgttct
    16381 gattccgatt tgtttacact cgtttcagag ctttgtgaag ttgaggatgt caaatcttga
    16441 ctagttgaag aatttgtaac actttcatgt tgactcgttt ctttattttc aagatccttt
    16501 ttcactactt ctttggattc ttttatttct gaatgacttg tagttttaat tgtagcagat
    16561 ttctcgatcg gaacatccac taaccaggca ccacttgaat ccacagtata gccttctggt
    16621 gtcttaccat tcacaagtaa ttgaccattt tctttcaaga agtaccattt atccttgtct
    16681 ttaatccaac ctatagctcg tgaaccatct gtcttgtaga aataccaatc atttgccttt
    16741 ttaagccagc cttgcttcat agctcctgat tcttctagat agtaatgatg tccagcaact
    16801 tctatctcac ctgtcttcat gataccagta gaatccatat agtaccaggc ttctttatct
    16861 tttacccagc ccgttttcat ttcccctgat ggagcaaagt aataccattg ccccttatat
    16921 tgaagccaac ctgtcttcat agagccatca acatccaaat aataccactg ctctttatct
    16981 tgaatccaac caatttccat ctggttttct ttgttaaaat aataccagat tccagcgatt
    17041 ttcttccaat ttttagcagc aacaccagag tctgtcaaat agaaccaacg attgttccat
    17101 tttttccatt gattctgtaa taagataccc gtttggttaa agtaatacca ttcaccctta
    17161 atttcattcc aaccaacagc atattctcct gtagaatcag gcgcttgata ccaccagttt
    17221 ccatatgaac tcttatgcca accagcttga aaacttggaa tcggcttgta ggaagttgaa
    17281 atgtttacta aaccgtcttg tcgaatatca aaaactgttg catcatagtc tttgctggct
    17341 gcgttgattc tctcaattcc tcgttctttg agccaattaa catactcact atcaacacca
    17401 tttttccaag gtagactatc cgaagtttga acaatcaaac tcggactcaa atttttaatg
    17461 aaatccttgg tatttgattt gttggtatca tggtgatgat taaacttcat caaatcaact
    17521 tttccaatga gaggaccata cttgtcttct gctccatgaa cattatctaa atcgccccca
    17581 aggtaaattt tcttgccatt gactttcacc acgctaatca aggaattgga attgtcatcc
    17641 caaattttct ttaattcacc cgatgaatca gtttcatttt cataattata gagctgaata
    17701 tccatgtccc caaactgaaa atgagcatcc ccttgtgtga tattttgaat aactgaaaca
    17761 cctttttctg cagcagtctg taaaacctta tcatagccat acagattatc ccatagacgt
    17821 tcagaattag taatacgact atcactatat ttcttaagat agactcggtc aactggatag
    17881 gtagacagta attcatcaac atttccaata tgatcactgt gggtatgggt caccaaaata
    17941 aaatcaagtt tttggacacc caattccttc aaacgacgaa agacacggtc tgtcagaaca
    18001 tgcttataag tggtattaat accctgtctc catggatagc gagaatcact tccatctggg
    18061 aaatcataat cttctcctgt atccaccatg gcaaaatgtc cattgctttc aagaataatc
    18121 gcatcactgc caccttcttg aacattgata aagtggattt tatttcctga actttcttga
    18181 gcctgaacat tcccatacca tgacaaacct aaaaaagcgc ctacaagtgc taaactagtt
    18241 aatttctttt tcattcttac tttctcaatc tctccaaggt ttccttaaaa atctctggga
    18301 tatctgcttt aaattccaag gtcttacctg ttctcggatg agtaaaacct aaagtcttgg
    18361 catgaagaaa ttgtccatgt cctttcaaag tcttgcgagg accatagacc tcatcaccag
    18421 cgactggatg gccgatataa gccatgtgga cacggatttg atgagtacgc cctgtctcca
    18481 gttgcaactc tactaagcta taatcgccaa agcgttccaa gacgtgaaaa cgcgtcactg
    18541 caggcttccc tttagcagtt acagcctgtt tcttacggtc tttttcactc cggccaatcg
    18601 gcgcttcaat tacaccacga tcattaggca gatttccatg aacaatcgcc caatatttgc
    18661 ggagagactt tttatccttg agttcttggg caagtgctag atgcgcatca tcgtttttag
    18721 caatcatgag aagacctgac gtatccttat caatacggtg aacaatccct ggacgcagaa
    18781 ccccattgat acccgacaag tccttaatat gatacatgag ggcatttact agggttccac
    18841 tggtatgacc agcactcggg tgcacaacca ttccctgagg tttgttaacg acagccacat
    18901 cctcatcttg gtagactatt tctagcggaa gatcctcagc cacatactct aatacctctg
    18961 gttctggcac atggtaagtg acgacatcac cctcttggac tgtgtattta gctttcttga
    19021 cttgaccatt gaccaagacc tggcctgatt taatttgttc attcgcgaga ctacgtgata
    19081 attctgacaa atctgacaaa gccttatcca aacgcagacc accagtttca attttaattt
    19141 ccatttattt cctcttttag cattgcaatc aataaaataa tcactccaac cgtcagatag
    19201 ctatctgcca cattgaaaat tgcaaagttg ataaagtcaa ggtggaacat atccacaaca
    19261 aagccctgac tgaccctgtc aataaagttt ccaagaccac ccgcgattat tagagtcaaa
    19321 cccaagacca tccagaatga gtcctccatg tgtttatgta aataccaaat ggcacctatc
    19381 acgacaacca gagtaatgac agcgaataac aactgctgat cttgtaagat agaaaaggct
    19441 gcacctcgat tttgcaggta ggtcaagcta acgaaattgg ggatccagga gcgcacttca
    19501 cccagtggaa tctgctggac gatataggat ttgaccaact gatccagccc aattaaaagc
    19561 agtacaatga ctgccactat tgctcttttt ttcatgattt cctcttttga tcaaaatatt
    19621 cttgcatgac ttctacgaag agagtcccag cttgactaag ctccacttct tcacgtttaa
    19681 catagaccat gcggttatct aggttatcct tgagacgaat aactgtaatg ccattaacac
    19741 tgtcactatc taaaaatcca gaacctgtcg cataggcgtc cgtccgctcc aaaataccat
    19801 tcaaggtggc acggtctgtc acattaaaca tctgtgagct agcgctggta tcgacaaagt
    19861 tctctgaata ataaaggtac tcgtctttct cttgagtgaa acgaaccgtt ggtaaatccg
    19921 ctaaatcctc catgactaat tcatctttct gggctaaagg atgaccctca cggagataaa
    19981 tatgggtatg gaaaggaatc aattcgatga cctccagacc taatttttca acccgttgca
    20041 taatcccctt tttattttga ttgttgaggt agataatccc aatctcacta tgcccttgcg
    20101 ccacttcatc taatatttga acagtagttg attcaaaaat acggaagttc ttatagtcag
    20161 gatagcgctc tgaaaaggcc gtaatagttg gtggtaagaa gtcatagtgc tggctagcaa
    20221 cggaaaattc atctttttct tcttcaggat tggcatactg attttgaaaa atatcaaatc
    20281 ctttaaccaa ttcttgcgct ttttcataaa attccatccc acgacgggtc aagaaagtcc
    20341 ctgagctggt ccgacggaaa atcttaaaac ccaactcttt ttccaaatcc cgaacagaaa
    20401 tagacagact cggctgacta acatacatct tttcagcagc ttcacgaaaa gtaccactat
    20461 tggcaatagc cacaacatag cgtaattgtt gaatgttcat cttctacccc taacttcttt
    20521 atcttttcat tataccatat tttagaagtt ttccaaaaag gaaaaaagaa catcctattc
    20581 ttcttaacta tcttcactat ctgcctttct caagccaacc ttattttcaa aatcaattca
    20641 aaaaaataac tggctacaca ccactacaat atcgaaaaga aaaacgttga ctatttgtga
    20701 aaaaagaaaa tgccggaaag ttccgacatt attttagtaa gctaacttcc tgaaaatagg
    20761 agcaaccaca catcccagaa ggcagtgata ttaatgagaa tatgaactag tattggatag
    20821 tagagatttt tagtcatgcg atacaataga gctaaaataa gacctccact agcataaatg
    20881 aaaaaagcaa gaggagttaa agcaaaattg atatgaatat aaccgaaaat aatagcagaa
    20941 agcaaaacat ctccgtacca aggcgagttt ttgaaaaagg ttgtcataat cacaccgcga
    21001 taaatcaatt cctcagcaat aggggcgatg aagcaaacga tgagcaagaa ataagggaac
    21061 tcctgtcgtc ccatcatttc tatcgtttca ttcaaagaaa tttgatttga aggcggggat
    21121 atgaaatacg aaaagaggaa gtcagacata tatgaaatga tgtagcccag taaaaggtag
    21181 atgaagtacc tcagctgcca cttgaaatga aaaattttct ttcctgcaaa aaccagtaga
    21241 tagatgaccg ctaagaaaag aactccactc tccatcaaaa gaagaatctg aaaaaattca
    21301 cgacttgctg gtagataggg ctttgcgaga taattgaaaa gcctccaaaa ccaagttgat
    21361 ttgtaaaaaa ttaaggacaa tactagtaaa atttgaatag ctcgtttttt catattaaat
    21421 cctctgtttt ctccccttgt ttcttcatat tcctaataaa ttttacttaa aatctcgcag
    21481 cacttccttt gcaaagatga ttacctcctc caatatatcc taaatcatcg gttcctctgg
    21541 gacaaaatcc atgaaccagc agagttaata ctggttctat ttcccaatcg tacctaccat
    21601 taggattttt accatatgga tctgctccac cttgtatcag ctctaattct tcatttgtta
    21661 gatttatatt ttttgtcatt aaaatcatga tatatttcct ccattattct tcagattagt
    21721 tgagtaatct gctactcata cctacttaca aaaaaactat tatattaagt tggtttttta
    21781 atttgtctag ttgcaacatt gacaaacata gtatagcata tctttgcgaa atatcctctt
    21841 caaatcatga attgtcatca aaacatctta aactataaaa tcaattagtc tcaagctttc
    21901 tatcaatttc ttctccaaaa tatgctataa taatagcaaa agataaagaa ggaagaccta
    21961 tgattaaact actagccttg gatatggacg gcaccctcct caatgaagcc aaggaaatcc
    22021 cacaagctca cattactgct attcacaaag ccattgaaaa aggtgtcaaa ctggttctct
    22081 gtacgggtcg cccccttttc ggtgtcctcc cctactacaa aaaactggag cttgacctcc
    22141 agaacgaata tattattgtt aacaacggtt gttcaactca ccagactagc gactggggct
    22201 tggttgactg gcaagaactg agtccagctg acatcgaata cctctatgac cttgctgaaa
    22261 agagtgatgt tcagttgaca ctttttgacg agtcacatta ttttgttctc ggtggcaaac
    22321 ccaatcaagt tattgaaaat gatgctaaac tagtattttc agacctgact gaaatttctc
    22381 ttgaagaagc gactagtgga aagttccgga tgttccaagg tatgttttta ggaacaaaag
    22441 aacaaacaga cgattttgag cagcgttttg ctgaagagct ttgccaacga ttcagtggag
    22501 ttcgttcgca gcctgtcatt tatgaagcaa tgccgcttgg aacgacaaag gctactgctc
    22561 tttcacgact agctgagatt ttgaagattg attcctcaga gattatggcc atgggcgatg
    22621 ctaataacga tatcgaaatg ctccagtttg cagggcttgg gattgcaatg ggaaatgcca
    22681 gcgattatgt caaatctctt gcggatgccg ttacatcaag caacgaagaa gacggcgttg
    22741 cgcgtgctat tgagaaatat attctataaa aaagaaaagc aaatagacag aagttactgc
    22801 tatttgcttt tttgctaata ttttaaaata cggactaatc aatagacaag aatagcgaat
    22861 cataaaaatc gatttactag atgccatagt atcttatagt tgctaataag aagttagtct
    22921 agcagaatga atctctcatt tctcccacac taatctgtaa tttgtctata catttctggt
    22981 cttctatctc gaaacaagcc ccagtttagg cgttcacttg ctcccttgtc taagtcataa
    23041 gtagctaaca gaacagcttc ttcttgtctt tcagctcgtt ctagaatagc tcctgtttca
    23101 tccgtcataa aggaggaacc gtagaagtca agactggaac tctgtccgcc attttcctca
    23161 ctaggagtaa cctcctctaa accataacga ttggctgcga tgactggaac aatattcgct
    23221 gctgcgtgcc cttgcatagt acgttgccag tgaccacaac tatctgtatc caaaattggc
    23281 tctgaaccga tagctgtagg ataaaagaac aattcagcac cattcaatgc aagacagcgc
    23341 gctgtttcag ggaaccattg atcccaacag ataccgatac caatcttagc atagcgagta
    23401 ttccagacct tgaaaccagt gttaccaggc gtgaaataga atttttcttg ataataatgg
    23461 tcatctggta tatgggtctt tcgataaacg cccagcactt ccccatctgc atcaatgacg
    23521 gcaatagagt tatacaagac attaccatct ttttcataga aactgattgg taaaacaact
    23581 tgtagttcct tagcaatcac cttaaaatgc tgaatggcag tattttccgc tacagattgg
    23641 gcatactggt agtagtcata ctgacgttcc tgacagaaat agggatgttc aaacaactcg
    23701 ggcaagagaa taatttgggc tccttgctca gcagcctgac gtactaaacg ctctgcggtt
    23761 tggatatttg ttgccacatc cttagcgcat tgcatctgaa tggttgcaac tcttacattt
    23821 ctcatctttt tctcctattc tggaatttgt tgggtgatac agtggatatt gccaccacct
    23881 aagagaatat ctctggctgg tattccgaca actttacggt ctgggaaaca cttgctgagg
    23941 atatctaagg ccacttggtc gtttacatcc tcaaactgtg gaaccaagac agccttgttg
    24001 gcgatataaa agtttacgta ggaagctgct agtcgttcac ctgcgtatcg cttttcttct
    24061 ccttcttcat agatgtagcc tggcaaatct tcttctgtca caacttgtcg aactgcaggg
    24121 ataggcaatt tatgaatggt gaagtgacaa ccttttgcat ctgtttcctg ttctaagagt
    24181 tcgagatctg cttttgacat ggcatactgg ggatcatttt cgtcatctgt ccaagccaaa
    24241 acaagctcag caggaccaac aaaggcagca acattatcga cgtgttcatt ggtttcatcc
    24301 tgataaatac cataaggaag ccaaataact ttttcagcac caagactttc taataatgtg
    24361 ttttcaatct cctctttagt caggttagga ttgcgaccag gactaagcaa gcaactttca
    24421 gttacgagaa tagttccttg accatcgcta tggattgcgc ctccttccag tacaaaaggt
    24481 ttagcatcat agacaggcct ttccaaggcc tcagcaaaac gactggctac ttggtcatcc
    24541 tcttcataat cttgataaag accatcatag gtgcctcccc aagcattgaa ggcccaatcc
    24601 acggctaatt tcttaccttt atcattgacg agaatggttg ggccagtatc acgcgcccag
    24661 gcatcattgg tgggaatgtc taaataaaca accttgtctc caagatagga ttgggcttca
    24721 gatagatagg cctgctccac caaaagatag actctttccc cttctgctat ggtctcgatg
    24781 atctgagtaa atgctctttt agcagccttt ccttgaaaag gccatgatcc tggtcgagtc
    24841 ggccatatca tgagggtacc atgatggggt tcgtactctg ctggcatgtg atagcctaat
    24901 ttttttggac tgtccatcat gataatctcc ctttaaagtc ttgatagcca aaagctttga
    24961 gtaagctaca gtctccctgt tcgtccatga gatagagact tggcaatcca ataccattaa
    25021 aggtattatt tttgacaaaa gaataaatgg ccatgtcttg aaaataaagt ctgtctccga
    25081 tttggactgg attttcaaaa ctataatcac caatcacatc gcccgtcaga caggtattag
    25141 aagaaagtct gtaggtatgg gctttttcct gtgcctcaaa gccatttctc aaaggtggac
    25201 gatagggcat ctcaagtaca tcaggcatat ggcaggtcgc agaggcgtct aaaaccaaga
    25261 tttccatacc gttttctaca atatctaata cctcagttgc taaataaccc gcattaagcg
    25321 caatggcttc accaggctcg atatagattt caagattgta agtttttcgg atacgcttga
    25381 tttctgaaat cagcaaatcc acatcgtaac cttctcttgt aatatgatga ccaccaccca
    25441 tattgagcca ttttacctca tgtaagtagg gaccaaactg ttcttctact tctttcaaag
    25501 ttgtttgtaa atcatctgct ccctgctcgc aaagggtatg aaaatgaagt ccgtcaacca
    25561 aatctagcaa atcactcgga atcttgtcta tagtaactcc aaagcgagaa cctggtgcac
    25621 aagggtcata gagcgcgtga tctccttgag ttgaacactg agggttgagg cgcaaaccaa
    25681 cactgacacc agcctctcga caacgcgaac catgcttacg caactgtctc tctgagttaa
    25741 agacgatatg gtctgttatc ccaagcaatt cctccatgtc ctcatccttg aaagctggtg
    25801 caaaaacatg gacttcacca ggaaattctt cccttgccaa tttggcctca tagagtccac
    25861 tagctgtcgt acctgataga tactggctaa tcaagggata agttttgtag agggaatatg
    25921 ccttctgggc aagcaagacc ttgcaaccgg cctcttcttg tacatattgt agaatgcggc
    25981 aattagcttc taacttggcc aagtcaataa cataggctgg tgttggtact tgttctaact
    26041 tcattagtcc accatttgtg gattttcaac cacaacccat ggcaaaccat actcattcaa
    26101 agcttccatg aatggatctg gatctaactc ctcaaggtta tacactccag cttgtttcca
    26161 agttccgttc atgactaatt ttgtcccaat catggctgga actcctgtcg tataagaaat
    26221 agcttgcgaa ccaacctctg catagcactc ttgatggtcg cagacattgt agatatagat
    26281 agtctttttg acaccgtctt tgacacctgt aaagatacat ccaatattgg ttttacctac
    26341 agtacgtggg ccaaggctag caggatctgg aagcaaggct ttcaaaaatt gaattggaac
    26401 aatttcttgg ccgttaaagt taatggtatc cgtacgaagg agtccaacat tttcaagaca
    26461 tttcatgtgc gtcaagtaag attgaccaaa agtcataaag aaacgaatgc gtttgacacc
    26521 tggaatgttc ttggccaatg attcgatttc ttcatggtga aggagataca tatctttttg
    26581 tccaacttga gggaaatcat actcacgctt gatagacata gcttcgactt cgacccattt
    26641 cccatcttcc cagtaagaac ctggcgcaga aacctcacgg agattaattt ctggattaaa
    26701 gttggttgca aatggataac cgtggtcacc gccattacag tctaaaatgt cgatataatg
    26761 gatttcatca aaatagtgtt tgagggcata agctgaaaag acactagtta cacctgggtc
    26821 aaaaccagaa ccaagaagag cagtcaagcc tgcttctttg aatttctctt gataagccca
    26881 ctgccatgag tagtcaaagt aggctgtaaa accaagttcc ttacaacgtt tttcgtagat
    26941 agcacgccac tcagggtctt ctgtgtcttc tgcttcgtag ttggctgtat cgatatagtg
    27001 aacacctgtt gccaaacaag catccataat ggttaaatct tgataaggca gagctacatt
    27061 caaaacagct tctggtttgt agctttcaat caaggtaatg acctcttcta ccttgtcagc
    27121 atcaagtgct gcagtttcaa ttttagtact tgttttgcct tctagcttcg ctttcaagtc
    27181 atcgcatttt gacttggtac ggctagcaat cataatctct gtaaatgttt cgctatcttg
    27241 acaaattttt gaaatagcaa cttgggcaac gcccccacaa ccaataacta gtaaacgact
    27301 catttttttc cttcctcttc ttctaaaatg tcctcaacat acttgggcaa cataaaggct
    27361 cccacgtgta agtttgcagt gtagtattct gtgaaaagct ggcgtttttt ccaaccttcc
    27421 ttgtcaaaat ctttgacagg gtggtatttt ttcgatgcaa atccaaacaa ccaatagcca
    27481 gctgggctag ttggaatatg ggcctgataa acccgactga ttggaaaggc ttgattgacc
    27541 ttgcggtgca tgcttcggca ggccgactca tcctcgtcaa agaagggact cccatgctgg
    27601 taaatcatga tgccgtcttc cttcagagct cgataactat tgccgtagaa ttccttggta
    27661 aagagtcctt ccgtatggcc aaatggatct gtcgcatcgt tgatgataat atcgtaatca
    27721 tcttcgcagt ttcgcaaaaa gcgtagccca ttttggtagt aaatggtaac acgaggatca
    27781 tctagccctg cagcaaagtc tgggaaatac tcacgacaga cctcgaccaa catctcatcc
    27841 ggttccacga tatcgatttg ttccagttca ggatagagtg ttaatacttg ggcaacaccg
    27901 ccgtcaccac ccccaataac caatactttc tttggatttg ggtggacagc catgggaacg
    27961 tgaacggtca tttcattgta gacgaaatca tccgcatctg agaacaagac atggccattt
    28021 aaaatcagta ttttcccaaa agctggcgta tccaagactt cgatatcctg ccattcactt
    28081 tttccagcgt aaagttgctt ggctgttctc agagacaatt tgacatctgg agtatgaact
    28141 tcagaaaacc ataaatccat ctatttctcc ttatattata tttagcgcag ttagctactg
    28201 ccaaagccca agtggtatac ttggaataag ccactgtgga ttagttcatt tcctccaatc
    28261 gcttgacgat ttccgaaagg gtctaaccac agctttttgt ttcaattggt aatgagtttg
    28321 ataacgcata gacgttttat ctcgtctaag gtaacaaggc aaaaagttcg tagataacta
    28381 agtagacttg aaatactata tctggaggta ctcccatgct ttatgtgggc attgatgtcg
    28441 ctaaaaataa acacgatgtt acagccttga atgtttcagg aaaactgttc ttaaaccact
    28501 cactttttca aataataaag ctggttttga actcttagat ctgtctcttc gacagctcaa
    28561 ccaagactgt ctcatcgctc ttgaagatac tggacattat gcctttaatc tactgaactt
    28621 cctgcatgaa caaggatata aagtttacac ctacaatcct ttgctcatca aggaatttgc
    28681 caaatcatta tcacttcgca agactaaaac ggataagaaa gacgctcatg gcatcgctct
    28741 taaacttctt tctgacccca atcgtgaaca atttcaacac gataatcggc aagtagacct
    28801 aaaaatactg gctagacata ttcatcgtct caagaaaaac agtctgattg gaaagtacaa
    28861 tacactcgtt gtcttgatat catctttcct gagttggata aaatcgttgg aaagcattca
    28921 gaatatacct accaactctt gacacgctac cctaatcctc agaaaaggat tgaggcagga
    28981 tttgataagc tgatagaaat taagcgattg accgcttcta attcaagggc tttttgccgt
    29041 gctctaaaat catcgccaaa tcatcaaatt gaaataagaa atagtttaga taaaactatt
    29101 gacttttctt atagtttgtc tttctcttaa tgacgttgat atgattgacc tctggatctt
    29161 ccgtcccttg gagggagcaa ccacgttcct tggcgaattg gatatagtcg acaatttctc
    29221 gtgtaatgcg ttcaccagga gccaagatag gaatacctgg agggtaacac ataacaaatt
    29281 ctccacagac ctgtccaaca gaatcatcca aagttaaact ttttctttct gaatagaagg
    29341 cttcttgcgg agacagcact aactcgggct gaatatattc tcctgctatc aaatcttttc
    29401 catctcttga atagagtctc ttaatatcag ccagagcacc aaccaagcgc tcgatgtctt
    29461 ggatgcggtc gccgatggaa atataggcca agatattgcc gatatcacca aactcgatct
    29521 gaatgtcgta ttcgtctcgc aagaggtcat aaacctcgat acctgttaag ccaataccct
    29581 gagtgtaaac tgacaactta gttacgtcaa aatcgcaaac cgaaacaccg tctattaact
    29641 cttttgagta ggcatagtag ccaccgatag cattgatttc acggcgggca tactcagata
    29701 gctcaatgac tttctcaaac gactctttac cacgaagggc caagttgcga cgtgaaatat
    29761 ccaaactagc catcaacaag taagaggcag atgtagactg ggtcaggtta attatctgac
    29821 gaacgtattc agaattcatc tgctccccga taagtaaaat ggagctttgg gtcaaactcc
    29881 caccagactt atgcatggaa actgctgcca tatcagcccc tgcatccata gcagaaattg
    29941 gaagtttatc agtgaaatgc aaatgcgctc cgtgggcttc atctactaaa accatcatgc
    30001 cagcttcatg agccatttct gtcaacccct ttaggtctga acagatgccg tagtaagtag
    30061 gattgttgat taggatagcc ttagcatctg gatggtcctt tatggcctgt gctactcggt
    30121 cattttcaag acctaaagcg ataccaatct taggatctac actcatctcg atatagatgg
    30181 gaatagcacc acatagaacc aacgcattga tagcagattt atggacattt cgtggcagaa
    30241 taatcttatc tcctgccttg caggttgcca gaatcatagt ctgcaccgat gaagttgttc
    30301 caccaatcat tagaaaggca tggctagctc caaaagcatc tgcagccagc tcctctgcat
    30361 cacgaataat cgaaatagga tggcctaaat tatccaaggg tttcatcgaa ttgacatcaa
    30421 tgcctacaca tttttctcct aagagttcga caagttctgg atttccccgt ccacgcttgt
    30481 gacctggaac atcaaaggga acaatccttt tcttgcgtaa cttcaccaag gcctcataaa
    30541 ttggggcttg gttttgatct aactctttca aaacatactc ctttcaatat ttttaggacc
    30601 ttatgaaaac taaggaacta aaggttgact catgaaaaaa gagcaggttt tcacctgctc
    30661 tgcaatcttc tgacgtgttt attttggttt ctgttgagta tgtctgttcc cgatgtttcc
    30721 taactctcta gtagcaaata ttacgtactt tattgatcgt ttcacaagat gacgtgtgct
    30781 ttcaccacac taaaaattta tgaattagga caagtgtcct aacatcaact tataaaagta
    30841 ggcttttaac cctatcaata atgtggcttt tcaaccacgc ttcggcattc aaccctgcct
    30901 gtccgtaggc attttttact cgggtttata tttgctagaa aacatcatct cattttctaa
    30961 gctttattac tatatcatgt ttttaagaac ttgtaaagta ttttttgata aaaaacaaaa
    31021 atatagtaga ttgaaactag aatagtacac ttctgcttct aaaacattat tagaaataga
    31081 ttttactgtc ctgatcgatt tgttctgttc ttgtttcatt ttactatatg ttcgtaaatg
    31141 aaagttctat aatgaagtta gccacccagc cctcctaaaa attagatggt tcaactagct
    31201 gatagctctt gtaggcataa gaaaacacct ctgtgttata cttgttgttc aaccacaaac
    31261 acaagaaagg cacagagatg caagacaatt atactacaaa agccaaacat ttgacaatcg
    31321 atagccgtcg cttaatcgaa agatggaaaa aagaagggaa atcaaataga gaaattgcct
    31381 ctctgcttgg aaaagttcct caaactatcc acactgaaat caagcgtggg acagtccgac
    31441 aatgtcttgg aaaagggcgc ttcaaagagg tttattctgc cgactatgct caacagtctt
    31501 atgaaaacaa tcgcaagcgc tcggtcagga aatcaagcgt gaccaaggaa ctaaaggaaa
    31561 agattctcca ctatcataac caaaaatttt cgcctgaaat gatggtgatg gttaaagggg
    31621 ttaacgtggg aatttcaacc atttactatt ggattcatca tggaaaattg gggttaagca
    31681 aacaggatct gctttaccct agaaaaggaa aagcgcttaa gaaacaggct agcaccaact
    31741 ttaaacctgc tggtcaatcc atcgaacagc ggtctgaagc tatcaatctt cgcttggaga
    31801 atgggcatta tgagattgat acggttctac ttacgagagc gaaaaactac tgtttgcttg
    31861 tcttgactga tcgaaagagt agacatcaga tcatccgatt gattccaaat aaaagtgctg
    31921 atgtggtcaa tcaggctcta aaactcatct taaaacaaca caagattctt tccatcacgg
    31981 cagataatgg aacggaattc aatcgcttgt ttgatgtatt ttctgaggag cacatctatt
    32041 atgcgcaccc ctatgcctct tgggaaaggg gaactaatga gaatcacaac aggctcattc
    32101 gtagatggtt acctaaggga accaagaaaa tgactcccaa agaagtcgca ttcatcgaaa
    32161 agtggattaa caactatcct aaaaaatgct tggactacaa gtcacccaga gaagacttct
    32221 ggatggctaa cttgaacttg aaatttagcg tcagaaacaa atcacgaaat tgattcaaat
    32281 tttgcaggtc gtttaaatat cctgcgtgcg ggtgttcttg atgctaacga tggaattatt
    32341 tccattgctg gtgtggttat cggagttgcc agtgccacga gcaatatctg gattatcttt
    32401 ttatcaggtt ttgcggctat cttagctggt gccttttcaa tggctggtgg agaatatgta
    32461 tccgtttcaa ctccaaaaga taccgaggaa gctgccgttt cgcgagaaaa actcttgcta
    32521 gaccaagata gggaactagc caaaaaatcc ctctatgctg cttatatcca aaatggagaa
    32581 tgcaaaactt ctgcccaact cttgaccaat aagatctttc ttaaaaatcc actcaaggct
    32641 ctggtagagg aaaaatatgg gattgagtat gaagaattta ccaatccttg gcacgctgcc
    32701 atttctagct tcgttgcctt tttccttaga agtttgcctc caatgctgtc agtgaccata
    32761 ttcccaagtg aatatcgcat ccctgctact gtccttattg tcggtgtggc ccttcttctc
    32821 actggttaca ctagtgccag acttggaaag gatccgacta gaacagctat gattcggaac
    32881 ctagctatgg tctcttgact atgggagtta ccttcctgct cgaacaactt ttcagcattt
    32941 agaatacaag aaatacctcg attttgaagt cgaggtatct tttttacatt tgcacaatct
    33001 tacgataact tcttgaagta atcatgaaaa tcagcacata ggcgatgagg aagatagcgc
    33061 agatagacaa ggtcacgatc aacatcatag tcgtatccag tacaccaatc acttttaaaa
    33121 tcaggctaag catatggtag gcaaaggcta gatgtatgaa ggcaaaaagc aaaggaagga
    33181 agaaaacagt taaaacctgt ttgttgatgg tttgcttgat ttgcttttga tctaaaccga
    33241 ctttctgcaa gataataaag cgttcacggt cttcatagcc ttcagaaatt tgtttgtagt
    33301 agatgaccag aacggttccg accataaaga taatggatag gaaaatacca ataaagaaga
    33361 caccgccaaa gaggacactc atttgagcac tagcatctgc tagagtgcta ccatacacat
    33421 agttaccttc agtgtttaat tgagcattaa acttttgtaa gtatttttca tattcttcag
    33481 cgaccttgag ttgctcttct tcactgatac ttacattcat accaccgtaa aactgattat
    33541 agatatccga atctgggaat tgatccaaaa aggcttgtaa atcaggaaca acaaggtaat
    33601 tgtaatcagt agtcaagata ttaaacttat ttggaacatg gttcacaatg aaatctttat
    33661 taaattcttc tttgacagaa aattgatgat catttagagt tagagctttc tgtcctttca
    33721 gtccgtcatt tttggcaaag agaccgacct catttcctga tagagacagt ttttgaccag
    33781 tcatattttc ataatctttt tggtcaaata ccatgaaaac tgttttgggt tggacacggt
    33841 tttgtccttt ttcaaaaata gttaacttgg ttccttcttg atttgcaata ccaaagttac
    33901 tgtaacgaag tacttctttc tctttgacac tataaccttt gtcacttgca aactggctca
    33961 agagtttgtc caaatcttct ttttcaacat tttgccctga aaccccaaaa tcatgaggat
    34021 ttagaacttt tttaaagctt tctgcggaat tgaaaatgct tgtcgctgct gacatggtta
    34081 ccaaaaccat tgttgacaaa atagcgatgg ttgctagtcc aaccgcattt ttcttcatac
    34141 ggaaaatcaa gttggaaaca gatatgaggt tattaggttg gtaatagtat ttcttgtttt
    34201 tctttaagat ttgtaggaag actgtaatcc ctgcattaaa caagagatag gtcccaaaga
    34261 taaccagtaa aacagctatg aagaaggttg ttaaggctgt aagaggatct tttaccgtaa
    34321 gggcaagata atagccaatc cctaaactta tggaaccaag aatagtttgg agaggtagga
    34381 aacgacctct tttctctccg cttgctttct cacgcgagag ctggagggca ttcatacggg
    34441 cgattcgaag ggcattcagg aacatgaggc ctaggaaaat caatccaaag acaagaagta
    34501 ctgcaatgac aactttcatc tggaaggtag caaccagctc aaccttcaat ttcattagtt
    34561 tgagcaggaa agcgaaaatt aacttgtcaa acaaggctcc aataccgata cccgctccaa
    34621 cagttagaat cccaaatacc actaactcct taaaggtcat actgataaga tgacgcttct
    34681 ccaagcccaa catgccataa attcctagtt ccttggaacg gttcttcatg acaaaactat
    34741 tggcatagag aacgataatg gctgacgcaa gggtgacgac aaacatacca aatccaagtg
    34801 tagcctgaat ggttgttcct ccacgaattt cagcaatctt gggattgaag gttagagagt
    34861 aaaagagata ggtgacagtg actgccaaga gaacagctag cgcaaaagga tagtagagtt
    34921 tgcggttttt aatcaagttc gataccgcta acttattagt taatcgaaac atactaattc
    34981 acctcgcttg ccatgacagt caaggtatca gagatttctt ggaacatctg acgttctgtc
    35041 ttctctccac ggtagatttg gttgtaaaga atgccgtctt tgataaagag aacacgcttg
    35101 gccctgctag cagctgctgt tgagtgggtt accatgagga tggtttggcc gcgctcattg
    35161 atttcatcaa agacatcaag taaggctgca gatgacttgg agtcaagagc tcctgtcggt
    35221 tcgtccgcaa ggagaatttc aggttcagtg atgatggcgc gtgctactgc tacacgctgt
    35281 ttctggccac cagaaatctc gtaagggtac ttctcttgta attggtttat tcccagattc
    35341 tcagctgtca ccaccaattt cttcatcatc tctgtaatag gtcttcttga caagacaagc
    35401 ggaagcaaga tattgtcctt tacagataga gtatctagca agttaaagtc ttggaagaca
    35461 aagcccaact tttcacgacg gaagctagag gcctgtgaat ttttaatggt tgcggtgtca
    35521 gttccattca agtaaacctg accacgactt ggtttatcca gcatagctag aatattgaga
    35581 agagttgatt taccagaacc agactcaccc atgatggcaa cgtagtcacc cttttcgacg
    35641 gtaaagtgaa tatccttgag ggcctctact tggttgccct gaaaacgagt tttataaatt
    35701 ttttgaacgt gttttacatc taaaagtgtc atgagaatct cctttcttaa tatcccatca
    35761 aatgaaatgt cgcttgcatc atagcgcatc ccagctgaac gcgctcgatt tctttgtgac
    35821 ttggttttct tgttttctta tgtaagattt gtttcatgat gttactcctt tgttctttat
    35881 gagtctagtt tacatcaaaa aaagacctct tgccataacc taaccttaca aaagagactt
    35941 taatcttaca tttttgtaag attgggggaa atgtaagcaa aattacttag aaaatgattt
    36001 gatttcctat ttttaaaatt gtaaaatata aatatgaaaa ggcttacttt ggaaaggagg
    36061 aagcgggaac taacatttta gtaagcttac ctagataaca taccattcaa tttaacactt
    36121 gcaagtcgtt caacctataa ggaaagaagg tgcgccttaa tgaaacacaa agaacatata
    36181 ctcatcggac ttctctatct gctctctcca ttcatcggtc agctcttagt tgaacacaca
    36241 cactttatca gtacagaatt taccggcact gcttatgtta tttgctggtt atcagttgtt
    36301 atcagcatcc accatttttc caaaaatgta ttgtctcaac agcaaaaata gattaaaaaa
    36361 ctgcgtttaa attactgctt ttatagtaaa atgaaataag aacaggacaa atcgatcagg
    36421 acagtcaaat cgatttctaa caatttttta gaagtatagg tgtcctattc tagttccaat
    36481 ccactatagt ttgtggatga agctggcgaa atattattaa tactattcaa aaatcaaagt
    36541 gcaaactata tcaacttcac attgccgact aaattacagc ctgcggctgg cttcctagtt
    36601 tgcactttga tttttattga gtataaaagt aaaaaagctt taaatcaagc agtttagact
    36661 attgatttaa agctttttgc gtattccaaa tcttttgtaa aacctcacca aaaccagcct
    36721 tcattatcgt caatggcttg agcttctttg cgtttacgtg ggcctgttcc gtacatttct
    36781 gcttcgattt cttccttggt tggcatgata gaagctagga tgatatagat aatcacccca
    36841 agtccaaagt ttgcgactgt aaaaatggca aacagaaaac gtacaagggt aacatcaaag
    36901 ttccacttgt ctgacagacc tgctaaaact cctgaaatca tgcgatttcg tctcatttta
    36961 taaaacttac tgttcatgat atttcctctt tctgctaggt tagacatagt atatcacgga
    37021 taggctcggc tttcatcagt cctcaggctg atttactaat agcaactttc ctcgacaaag
    37081 tccacagcga tagcgtttgg tatcaatcct acgcttacgc tgataagttt gctggcagga
    37141 ttggcaacga tagagcttga ttggcttgga gttactattg ggcaaggatg gtacaaaccg
    37201 taatccatcc actgctttca acagttcctt aaaatcccga tccttgtgtt gatagccttt
    37261 cccttgaaaa tagaggtgat aatgacagag ttcatgtcgg acaattttcc taaaaacgtc
    37321 caaccccagt tcctgataaa ccttgggatt aaaatccaaa tgcccatctt tggggaaaaa
    37381 tcgcccacct gtcgaacgta gacgcctatt ccactggaca tgatggataa aaggtctgcc
    37441 gaagtcttct agtgaaacct gcttgacgta atcagtcagt ttcatttgga gctaggagag
    37501 acagattaac tttttcacgt tcagtatcaa ttttcttaac ccaaacgctc accaaatctc
    37561 caactgccac cacttgacta gggtgtttga taaacttgcg actcatatgg gaaatatgga
    37621 tgagaccgtc ctcatgaatt ccgatatcaa caaaagcacc gaaatcaaca acgttacgca
    37681 ccactccttc tagcttttgt ccaaccacta agtccttgat atctaggaca tcttgacgga
    37741 gaactggagc atcaaaggaa tcacggaaat ctcgacctgg tttgagaaga tctgcaatga
    37801 tatctttaag agtttctgga ccaaggtcta actcttgcgc catttccttg actgaaagcg
    37861 acttgagttt gctttgggcc tcttcattca gatccttaat gtccaagcat ttgaagagtt
    37921 ccttaacggc agcgtaattt tctgggtgaa ctcctgtatt atcaaggata ttgctacttt
    37981 cagggatacg gaggaaacca gcagcctgtt caaaagcctt ggcccccaaa cgaggaactt
    38041 tcttgatttg ggagcgtgaa gtgatttttc cctcttcctc acggtatttg acgatatttt
    38101 cagaaatggt tttattgagt ccagctacgt gtgaaagaag agctgggcta gctgtattga
    38161 cattgacacc aacttggtta accactgtat cgacaacaaa gtccagactc tcagatagtt
    38221 tcttctgact gacatcgtgt tggtattgac cgacaccaat tgacttagga tcgattttga
    38281 ccaattccgc aagaggatct tgcaaacgac gggcgataga aatggcagag cgtttttcaa
    38341 cggtcaagtc tggaaactcc tgacgagcaa gttcgctggc agaatagaca gaagcaccac
    38401 tttcattaac gataacatag ctgacttcag ggaaatcttt cagaacttcc gctacaaaag
    38461 cttcactttc acgactggcc gttccatttc caatggcaat aatctctaca ccgtattgac
    38521 caattaaatc tgctaaatct ttcttggctt cttcgatttg acgagctgat gctggtttaa
    38581 caggataaat aacctgagtt gtcagcattt ttcctgttgc atccacgaca gctagcttgg
    38641 cacctgtacg aaaggctggg tcaaacccaa gaaccacgcg ccctttcagt ggagcaacca
    38701 agaggagatt gcgcagattg tcagaaaaaa gttggatagc tccctcttca gctttctcag
    38761 ttaattctgt ccgaatacga cgctcaatag caggcaagac ctttttctta acggattgct
    38821 gaacaacttc atcaatataa gcatttttca ccttgaaacg agtaacaaag aaggcaagaa
    38881 tacggtccgt cgcatgttca aaaccgatct tcaagacacc aagtttctcc ccacgattga
    38941 gagccaaggt acgatagcct tgcatagttc caactgtctc tgaaaaatca taataaatct
    39001 gaaaaacctg cttttcatca agactttcat ccttggcttg agaagtgagt ttagagtgtc
    39061 tcagcacttc ctgataagtc atagaacgca aggtcacatc ttccgataag gcttcgacca
    39121 aaatatcaac tgcaccggtc aaggcttcct tgccagtcgc aaatccttca cagacgaact
    39181 tttcagcttc tttctctaag tcaactatat tctgcaaaat caagcgagca agaggaaaga
    39241 gtccagcttc acgggcaatg gttgccttgg tacgacgctt ttccttataa ggaagataga
    39301 gttcttcaac gtctgctaat ttttcggcaa ctaagatagc ttcttccaat tccttggtca
    39361 acttgccttg ctcttgaatc ttagctaaga cagcttcctt acggtcattg agatttgtca
    39421 gacttttatc caaatcaata atagccttaa tcgccacctc atccagacta ccagtcatgt
    39481 ccttacgata acgcgcgata aagggaatag tcgccccttc agctgtcaaa cttagaacgg
    39541 tatcaatttg ctttaacgtc actcccaaat cctgagagat tttttcatat tttttatcca
    39601 taaatctatt ataccacaag ctggaaggct ttctccaatc cttttcatac tcaatgaaaa
    39661 tcaaaaagca aactaggaag ctagccgcag gctgctcaaa atactgtttt gaggttgtgg
    39721 ataagactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
    39781 tcagtaaccg tactacggta aggcgaagct gacgtggttt gaagagattt tcgaagtgta
    39841 tcaactatcg aaaacaaatt aaaaaactcc cttttccgca aaataatagt ataatagagg
    39901 tagaatttag aatcgaggta cacctatggc tgtcaaattt acaaaacgag acgacttgga
    39961 caagatgttt gaagagtttg ctaaactccc tgatttgaaa caagttactt tccctgatga
    40021 caaagagaaa aaagtcaaag cagaaaagaa aaactagatg actgcttttc aacaactccc
    40081 atctagtgta cttcaaactg gagccatttt tctctccatt atcattgaag cccttccctt
    40141 cgttctgata ggaagcattg tctcagggct gattgaagtt tatatcacac ctgacaaggt
    40201 ttatcatttt ctccctcgaa atcgttgggg gagaatcttt tttgggacct ttgtcggtat
    40261 acttttccct tcttgtgaat gtggaatcgt ccccatcatc aatcgttttc tggaaaaaaa
    40321 ggttccaagt tacacggccg ttccttttct tgtgacagca cctgttatca atcccattgt
    40381 tctttttgcg acctattctg cctttggcaa ctccttccat gtcgccctat tacgagctct
    40441 gggttccatt cttgtggctg taatactagg aatttttcta ggatttttct ggcaagaacc
    40501 gattcagaaa gaaaatcgtc tggcttgtca tgagcatgat ttttcttact tgagttctgc
    40561 aaaaaaagtt tttcaagtct ttgtgcaggc cattgatgaa ttttttgata cggggcgtta
    40621 tttggtattt ggctgcctct ttgcttctat aatacaggtc tacgttccga ctcggattct
    40681 gacctctatc agtgcgactc ctctttttgc catcctgctc ttgatgcttt tggcctttct
    40741 tctttcgctc tgtagtgagg cggatgcctt tataggtgct tctctactct cgagtttcgg
    40801 tttggctcca gttctggcct ttctcgtcat tggcccaatg ctggatatca aaaatattct
    40861 catgatgaaa aattacttga aagcacgatt tattagtcac ttcattacga ttgtgactct
    40921 ggtcgtttta gcctattctc tcttgattgg agtcatccta tgattcgatt tttagtttta
    40981 gctggctatt ttgaactgac tatttacctc catctgtcgg gcaaactaaa ccagtacatc
    41041 aacatgcact attcctatct ggcctatatt tccatggtgc tttcctttat cttggcaatt
    41101 gttcaattgt atatctggat gaagcaagtc aaaacccaca gtcatctgaa cagccgattg
    41161 gccaagatga cgagtatttc tcttctggct attccacttg tcatcggctt aactttccca
    41221 actgttagct tggattctca gactgtttct gctaaaggtt atcatttccc cctatcggaa
    41281 ggaacggatc tagccattca gacaagcgaa gggacgacaa gccaatattt gaaaccagat
    41341 accagttctt atttttcaaa atcagcctat gaaaaggaaa tgcgaacggc ggcggataaa
    41401 tacttatccc aagatagtat tcagatcact aatgaaaact atatggaagt catggaggct
    41461 atctacgact atccagatga gtttgagggc aagacaatcc agtttacagg ctttgtctat
    41521 aacgacccca gtcatgccaa tagtcaattt ctgttccgat tcggcattat ccactgtatc
    41581 gcagattctg gtgtctatgg attgctgacc aagggcaata cccggcagta tgaaaacaac
    41641 acttggattt cagccaaagg aaaactggtc aatcactacc ataaagaact caaacaaaac
    41701 cttccaacct tggaaatcga cagctttacc aaagtcgata aaccagaaaa tccctatgta
    41761 tatagagctt tttaagaaaa tcaaaataaa aacgaacaag ttctcttctg aataaca
//
LOCUS       DAVLIK010000016        35001 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLIK010000016 DAVLIK010000000
VERSION     DAVLIK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35001
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.016"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            425..685
                     /locus_tag="VXE87_000911"
     CDS             425..685
                     /locus_tag="VXE87_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842481.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            639..860
                     /locus_tag="VXE87_000912"
     CDS             639..860
                     /locus_tag="VXE87_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842482.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            1179..2108
                     /locus_tag="VXE87_000913"
     CDS             1179..2108
                     /locus_tag="VXE87_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0842483.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            2122..3045
                     /locus_tag="VXE87_000914"
     CDS             2122..3045
                     /locus_tag="VXE87_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0842484.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            3303..4778
                     /locus_tag="VXE87_000915"
     CDS             3303..4778
                     /locus_tag="VXE87_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0842485.1"
                     /translation="MKNWKKYAFTSASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            5050..6036
                     /locus_tag="VXE87_000916"
     CDS             5050..6036
                     /locus_tag="VXE87_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0842486.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            6158..7018
                     /locus_tag="VXE87_000917"
     CDS             6158..7018
                     /locus_tag="VXE87_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0842487.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(7196..8260)
                     /locus_tag="VXE87_000918"
     CDS             complement(7196..8260)
                     /locus_tag="VXE87_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842488.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(8322..9233)
                     /locus_tag="VXE87_000919"
     CDS             complement(8322..9233)
                     /locus_tag="VXE87_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0842489.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(9226..9819)
                     /locus_tag="VXE87_000920"
     CDS             complement(9226..9819)
                     /locus_tag="VXE87_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0842490.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            complement(9806..10132)
                     /locus_tag="VXE87_000921"
     CDS             complement(9806..10132)
                     /locus_tag="VXE87_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0842491.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            complement(10271..11437)
                     /locus_tag="VXE87_000922"
     CDS             complement(10271..11437)
                     /locus_tag="VXE87_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0842492.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            11495..12652
                     /locus_tag="VXE87_000923"
     CDS             11495..12652
                     /locus_tag="VXE87_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0842493.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIIEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            12694..14544
                     /locus_tag="VXE87_000924"
     CDS             12694..14544
                     /locus_tag="VXE87_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0842494.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQEIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(14726..14824)
                     /locus_tag="VXE87_000925"
                     /pseudo
     CDS             complement(14726..14824)
                     /locus_tag="VXE87_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(14850..15482)
                     /locus_tag="VXE87_000926"
     CDS             complement(14850..15482)
                     /locus_tag="VXE87_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0842495.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(15504..16376)
                     /gene="sdaAA"
                     /locus_tag="VXE87_000927"
     CDS             complement(15504..16376)
                     /gene="sdaAA"
                     /locus_tag="VXE87_000927"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0842496.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(16385..17056)
                     /gene="sdaAB"
                     /locus_tag="VXE87_000928"
     CDS             complement(16385..17056)
                     /gene="sdaAB"
                     /locus_tag="VXE87_000928"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0842497.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            17298..17870
                     /locus_tag="VXE87_000929"
     CDS             17298..17870
                     /locus_tag="VXE87_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0842498.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(17923..18243)
                     /locus_tag="VXE87_000930"
     CDS             complement(17923..18243)
                     /locus_tag="VXE87_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0842499.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            18668..18955
                     /locus_tag="VXE87_000931"
     CDS             18668..18955
                     /locus_tag="VXE87_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0842500.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            19007..21115
                     /locus_tag="VXE87_000932"
     CDS             19007..21115
                     /locus_tag="VXE87_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0842501.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            21112..21753
                     /locus_tag="VXE87_000933"
     CDS             21112..21753
                     /locus_tag="VXE87_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842502.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            21960..22766
                     /locus_tag="VXE87_000934"
     CDS             21960..22766
                     /locus_tag="VXE87_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0842503.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            22783..23979
                     /locus_tag="VXE87_000935"
     CDS             22783..23979
                     /locus_tag="VXE87_000935"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV0842504.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVAVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQTGATTIAHGCTGKGNDQVRFEVSIAALDLNLKVIAPVREWKWSREEEIYYAKEN
                     GVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSSATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPNSLYDENLATYTSADTVDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            24039..24827
                     /gene="argH"
                     /locus_tag="VXE87_000936"
                     /pseudo
     CDS             24039..24827
                     /gene="argH"
                     /locus_tag="VXE87_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            complement(25116..25979)
                     /locus_tag="VXE87_000937"
     CDS             complement(25116..25979)
                     /locus_tag="VXE87_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842505.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            26445..28664
                     /locus_tag="VXE87_000938"
     CDS             26445..28664
                     /locus_tag="VXE87_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV0842506.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDIILSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQAIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIIDKTTIVVAHRLSTILR
                     CDKICFLENGTIVEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDIEEVTYG"
     gene            28657..29124
                     /locus_tag="VXE87_000939"
     CDS             28657..29124
                     /locus_tag="VXE87_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0842507.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            29121..30473
                     /locus_tag="VXE87_000940"
     CDS             29121..30473
                     /locus_tag="VXE87_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEV0842508.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQALQNELLQLQQQGDSPSLSDTTSADDKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNNPTSQAYNIYAQLISEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            30621..30926
                     /locus_tag="VXE87_000941"
     CDS             30621..30926
                     /locus_tag="VXE87_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPAR17_0115 family bacteriocin-like peptide"
                     /protein_id="HEV0842509.1"
                     /translation="MELILPNNYVDLEQEEMMYLDGGEPMSISAIVALAITIGGASYS
                     TGYVLGERVYYSGYKNSDYQKNKWGIRGAMLAAFGAIGAVVMLGFENRYYALVTGRG"
     gene            31260..31613
                     /locus_tag="VXE87_000942"
     CDS             31260..31613
                     /locus_tag="VXE87_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0842510.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            31610..32338
                     /locus_tag="VXE87_000943"
     CDS             31610..32338
                     /locus_tag="VXE87_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842511.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            33471..33710
                     /locus_tag="VXE87_000944"
     CDS             33471..33710
                     /locus_tag="VXE87_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842512.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            33695..33973
                     /locus_tag="VXE87_000945"
     CDS             33695..33973
                     /locus_tag="VXE87_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842513.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            34259..>35001
                     /locus_tag="VXE87_000946"
     CDS             34259..>35001
                     /locus_tag="VXE87_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842514.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKSEAAKKHYEEVKKKAEDAQKKYDEGQKKTVEKAKREKEASEKIAEATKEV
                     QQAYLAYQQASNESQRKEADKKIKEATQRKDEAEAAFATIRTTIVVPEPSELAETKKK
                     AEEAKAEEKVAKRKYDYATLKVALAKKEVEAKELEIEKLQYEISTLEQEVATAQHQVD
                     NLKKLLAGADPDDGTEVIEAKLNKGEAEL"
BASE COUNT        10968 a         5881 c         7407 g        10745 t
ORIGIN      
        1 agtgtattga atctataaca gtacaccttg gctgctaaaa tatttctata aattaatttg
       61 actttcctga tagagttgtt cacatcttat ttcaaatcac tataaaagct ctataatctc
      121 tttataagat ttgcccatca gacgaaatat aatggattga aactagaata gtacacctct
      181 acttctaaaa cattgttaga aatcgatttg actttcctga tcgatttgtc ctgttcttgt
      241 ttcattttac tatagaacga tttgaaggcg tttatgatat ttagctgtac gagagtcttt
      301 taaaagtgtt ttgatggttt ggatttcttc tttagttgat ttcatatcac tgttatataa
      361 tgctttttga ttttagtcta gtattagtaa gcagactcaa accttagaaa atcttttgag
      421 atcattgaca ggtgtatcga atcctaccac agattcagca cgtctggttt tggcagaggc
      481 taagaaagct tttgcagatg atagtttgac agagcaaggt ttacgtgata tcttgcaaac
      541 agtcaaagat gccattgctt ccctagagtc cattaaggaa agccagtcag caactaagga
      601 tggaggacaa acagcgggca aagaaacagc aggagaagat gagtctgcaa atcaaactca
      661 agaaattagc caaggaatta agtaaacttc ttaaagactc aaaccttgaa acagtagata
      721 aggatgtcct tgaaaactct caaaaagaac ttcaaaaagc agttttgttc ttggcagatg
      781 aaaaaggctc tgagcatact gaagcagagg tgattgataa tcttaaagag gttattgcta
      841 agttgaaagc aaacgcctaa taacatatta aaaatctcca gattaggaac tatcgctgag
      901 ttccctagtc tggagatttt tcagtatacc ccgttgttgg atgcttataa cagagtgacg
      961 ccatcactgg gctaatagag ataaaataaa caattgattt aggacatttg tttgatagtg
     1021 gtgataaagt tttaaatctg ctacataatt tgtggagttt tttctataat taggagttta
     1081 acctaacctg caaataggag tatactaata atgtaatcgt tatcaaaagt ctaaaaaaga
     1141 atttttagat ggatatcaaa ataaaaaggg aggaaattat gaaaaagttt tcaaaaacat
     1201 tgagagacaa ctggatcttt ctcttgatgg ttttgccagg ggcactctgg ttgattctat
     1261 tcttttacat tccagtattt gggaacgtgg ttgccttcaa agactaccac atgaccagta
     1321 atggtttcat agatagtatc ataaatagta aatgggtcgg actcgataat ttcagattct
     1381 tatttagttc aagagacgcc tttattatca cacgaaatac cgtcctctac aatcttggct
     1441 ttatctttct aggtttagtt gtatctgtag ggattgccat tatcctcagc gagctccgtt
     1501 ctaagagaat ggtgaagatt ttccaaactt ctatgttgtt cccttacttc ttgtcttggg
     1561 ttatcatcag tttctttaca gatgccttcc taaatattga taaaggggtg ttcaatcatc
     1621 tattggaaag tcttggtctc aaagaagtca atttctacgc tgacctgggc atctggccct
     1681 atctcctact tttcctaggt atttggaaag gttttggata tagcagtgtc atgtactatg
     1741 cgacgatcat gggaattgat ccaacctact acgaagcagc gacagtggac ggagctagca
     1801 agtggcaacg tattcgcaac gtaaccattc ctcagttgac tccgcttgta actgtattga
     1861 ccatccttgc agtcggaaat atcttccgcg cagacttcgg tctcttctat caaatcccac
     1921 acaatgctgg tcagctttac aatgtaacca acgttttgga cgtatatgtt tttaatggtt
     1981 tgactcagac agcagatatc ggtatggctg cagcagccgg tctttaccaa tccgttgttg
     2041 gtttgattct ggttatccta tcaaacttgc ttgcaagacg agtcgatcca aactcagctt
     2101 tgttctagaa aggaggagaa tatggcaaaa aagaaaatta aaaaagaaaa aattgataat
     2161 gtcggcattc actccttcag taagaaagca gatatcttct tcagtatcat ttcgggtttg
     2221 attgccctct cttgtatcct accttttgta ttcgttatca ttatttcagt gacagacgag
     2281 aaaagcctcc tccaatacgg ctatagcttc ttcccatccc aatttggctt agacggtttt
     2341 gagtttttgg cacagtttaa ggataaaatc ctacaagccc tcttcatctc tgtctttgta
     2401 accgtagttg ggacattgac aaatgtcttt atcacaacaa cctatgccta cgctatttca
     2461 cggacaacct ttaagtatcg cagattcttt accatcttcg ttctgctcag tatgttgttc
     2521 aacgctggtt tggtaccagg ttatatcatg gtgactcgtg tgcttcagct tggggatact
     2581 gtttgggcct tgattgttcc aatgcttctc tcaccattta acatcatctt gatgcgttcc
     2641 ttcttcaaga agaccattcc agaagccatt ctagaatcgg ctcgtatcga tggtgccagt
     2701 gaagcccgga ttttcttcca aatctgtttg ccattgtcac taccaggtat cgcaaccatc
     2761 acgctcttaa cagctcttgg tttctggaat gactggttca acgcccttct ttacatcaag
     2821 agtgacaact tgtatccatt gcaatatttg ctcatgcaaa tccaacaaaa tatggactac
     2881 attgccaaag cggtcggctt gactggtcaa ctgggagttg ctctaccgaa agaaacaggt
     2941 cgtatggcca tggttgtggt tgcaaccctt ccaatcgcga ttttgtatcc atttttccaa
     3001 cgctactttg taaaaggttt gactatcggt ggtgtgaaag aatagtgctt attgagaaat
     3061 aacatttctc agttcccaac ttcccttgtg tgaagttaat actcttcgaa aatcaaattc
     3121 aaaccgtgtc aacgtcgcct tgccgtagat atatgtaact gacttcgtca gtcttatcta
     3181 caacctcaaa gcagtgcttt gagcagcctg cggctagttt tctagtttgc tctttgattt
     3241 tcattgagta taagatcatt acattgttta taagtttaaa aataaaaaaa ggagttttta
     3301 tcatgaaaaa ctggaaaaaa tatgctttta catctgctag tgtagtcgct ctggctgcag
     3361 gtcttgctgc ttgtggaaat ttgacaggta acagcaaaaa agctgctgat tcaggtgaca
     3421 aacctgttat caaaatgtac caaatcggtg acaaaccaga caacttggat gaattgttag
     3481 caaatgccaa caaaatcatt gaagaaaaag ttggtgccaa attggatatc caataccttg
     3541 gctggggtga ctatggtaag aaaatgtcag ttatcacatc atctggtgaa aactatgata
     3601 ttgcctttgc agataactat attgtaaatg ctcaaaaagg tgcttacgct gacttgacag
     3661 aattgtacaa aaaagaaggt aaagaccttt acaaagcact tgacccagct tacatcaagg
     3721 gtaatactgt aaatggtaag atttacgctg ttccagttgc agccaacgtt gcatcatctc
     3781 aaaactttgc cttcaacgga actctccttg ctaaatatgg tatcgatatt tcaggtgtta
     3841 cttcttacga aactcttgag ccagtcttga aacaaattaa agaaaaagct ccagacgtag
     3901 taccatttgc tattggtaaa gttttcatcc catctgataa ctttgactac ccagtagcaa
     3961 acggtcttcc attcgttatc gaccttgaag gcgatactac taaagttgta aaccgttacg
     4021 aagtgcctcg tttcaaagaa cacttgaaga ctcttcacaa attctatgaa gctggctaca
     4081 ttccaaaaga cgtcgcaaca agcgatactt cctttgacct tcaacaagat acttggttcg
     4141 ttcgtgaaga aacagtagga ccagctgact acggtaacag cttgctttca cgtgttgcca
     4201 acaaagatat ccaaatcaaa ccaattacta acttcatcaa gaaaaaccaa acaacacaag
     4261 ttgctaactt tgtcatctca aacaactcta agaacaaaga aaaatcaatg gaaatcttga
     4321 acctcttgaa tacgaatcca gaactcttga acggtcttgt ttacggtcca gaaggcaaga
     4381 actgggaaaa aattgaaggt aaagaaaacc gtgttcgcgt tcttgatggc tacaaaggaa
     4441 acactcacat gggtggatgg aacactggta acaactggat cctttacatc aacgaaaacg
     4501 ttacagacca acaaatcgaa aattctaaga aagaattggc agaagctaaa gaatctccag
     4561 cgcttggatt tatcttcaat actgacaatg tgaaatctga aatctcagct attgctaaca
     4621 caatgcaaca atttgataca gctatcaaca ctggtactgt agacccagat aaagctattc
     4681 cagaattgat ggaaaaattg aaatctgaag gtgcctacga aaaagtattg aacgaaatgc
     4741 aaaaacaata cgatgaattc ttgaaaaaca aaaaataatc agctaaattg atttcgtgta
     4801 ttcattccta actcctaaaa taagaatcac tgctttcctc aggttggtct ggggagggca
     4861 gtggtttttt tggcacaagg atatagatat ccatgttttc tcttgtcctt attttaacca
     4921 ttcaggaaat ttcgagaacc ctctacaatt tccagtcaaa taaattgcat tcgttttctc
     4981 aagcaggtat actagtatgg ataaataaaa aatttagaaa atttaagaat agaaaagaga
     5041 acaaatctta tggcaaaaga tattcgtgtc ttactttact acctttatac tccaattgaa
     5101 aatgcagagc aatttgctgc agaccacttg gctttctgta aatcaatcgg ccttaaaggc
     5161 cgtatcctag tcgctgacga gggaattaac ggaacagttt caggtgacta tgaaacaact
     5221 caaaaataca tggactacgt tcacagcctt ccaggaatgg aagaactctg gttcaagatt
     5281 gacgaagaaa gtgaacaagc cttcaagaag atgtttgttc gctacaagaa agaaattgtc
     5341 caccttggtt tggaagacaa cgactttgac aatgacatca acccacttga aacaacaggt
     5401 gcttacttgt ctccaaaaga gttcaaagaa gcgcttcttg ataaagatac cgttgtcctt
     5461 gacacacgta atgattatga gtatgaccta ggacatttcc gtggggctat tcgcccagat
     5521 attcgcaact tccgtgagtt accacaatgg gtccgtgata acaaggaaaa attcatggac
     5581 aagcgtgtcg tggtttactg tacaggtggc gttcgctgtg agaaattctc aggctggatg
     5641 gtccgtgaag gctacaaaga tgtcggccaa ttgcacggag gaatcgcaac ttacggtaaa
     5701 gacccagaag ttcaaggtga gctttgggat ggaaaaatgt acgtatttga cgagcgtatc
     5761 gccgttgatg tcaaccatgt caacccaacc atcgtaggga aagactggtt tgatggaaca
     5821 ccatgtgaac gttatgtcaa ctgtggaaat cccttctgta accgtcgtat cttgacatca
     5881 gaagaaaatg aagacaagta ccttcgtgga tgctcacacg agtgccgtgt tcacccacgt
     5941 aaccgctatg tttcaaaaaa tgaattgaca caagctgaag tgattgagcg cctagccgct
     6001 atcggtgaaa gcttggatca agcagctact gtataagatc aaacagtcct caggggctgt
     6061 ttttctatgc tttgtactca aaaatctaaa gtttgtttct gtatctttca gaaaaataag
     6121 gtatactgta tgtaaacgat ttcaaaggag tccagttatg gcaaaaacat tttttattcc
     6181 aaataaacag agcattttag gagaacaaga gattttgaat gccaagtcga tcttggcctt
     6241 gctagacggt ttggagtcac atagctatga tgtagtctat ctccgtcagc ctcttaatcg
     6301 tctcgaatat atcgagtgtg cgatagtggg gcaatcacaa tttctcttta aggtcagtta
     6361 tgctgatggt caaaaggctt accgtgtcga tcttcctgac ctactaacaa agacagactg
     6421 gcagattatc aagtcatttt tagatgcttt gcttgcttat acagggactg atattgaagg
     6481 gctagatggt tttgattttg aagcttattt ccaagcaagt attcaagcct atctagcaga
     6541 ccctgtagct cgttttacga tttgccaagg aatttttaat cctattttct ttagtcgtga
     6601 gaacttgaaa agctttttag aggcagatgg cttggctcag tttgaagcgc gtgtgcgtgc
     6661 ggttcaagag acagatgcct actttgcgag agtttccttc tatcaggatg gagaaggaaa
     6721 agtgcatggc gtttaccatc tagctcaagg agtcaagaca gttttaccga gagaaccgtt
     6781 tgttcctgca gcctatattg agcaattggt ggataaggaa gtgcagtggg agattgactt
     6841 ggttcaaatc acaggagatg gctctaaacc agaagactat gaagccattg cccgcttgga
     6901 ctatgcaaaa ttcttagagg tattacccct atctttttac caccaactag acgccaatca
     6961 aatagaagtg caacccatat tagacaaaga ttttaaagca ttagcacaag aagagtaaag
     7021 cagaagcagg tcaatcgact tgcttttttg acatagaaaa aatcctgcca aggatgacag
     7081 gattgctact caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgtacttga
     7141 gtacggtaag gcgaagctga cgtggtttga atttgatttt cgaagagtat gaagtttaaa
     7201 gaaaggccaa gatacgaaga taatctccaa tcagtgccac ttcagctaca aagaagagga
     7261 ggataataac tccgttcaca aggacagaca agaataattg atagaaggag tcggtttcac
     7321 ttgcttgact tggtcttgta atgatatgga gactggcaag cagaatgatt ccaatgctaa
     7381 tcacacacaa gagagctgta aatcgtaggc tatcaaagaa agcaaagaaa ctagcaatag
     7441 cagtgaggaa gattggaatt gccaagagtt gactatattg ttggagaacc ttgtctagcg
     7501 tccagtcctt ttcctggtgg ataaatcgtc tcacaacgaa actacccaag aggaatgaaa
     7561 agaagaagag tgttgtcgct actaggatag agacgataga aaaaagagtt aaaggagcta
     7621 gctgctcagg gaagcgactg ttaatgcttg ctatatgtcc atagtaagca tgtttgatgt
     7681 gatagatact aaagaaaaag gaagatgcag aaaacagaat gagcaagaga aaggctgtgt
     7741 aactgtgtgt gatacttgtt tccaacttac ttgtaggaga tttgatcgct tccactagcc
     7801 aagaccaaaa atcaagcact tgctctttcc atttatccct agattttgga gcttggtcgg
     7861 ggatataagg actttctaaa gatttactga taagaagtgg ctctttcgtg gttgcttttt
     7921 gctgaggaag agcttcttgg ctctcttcag ctatagtgac tttttctgtt tctttagaaa
     7981 ggtctgactc ttcttcagta gaattagatg ccttcttttc ttctatttct gttctcgctt
     8041 caccgacttc aggagtttca attttctctt cttgctggct ttccagttcg acttcagctt
     8101 gagagacttc ctcctctact tgagtatttt ttccaattgg tgtatcgaaa tcggctatcg
     8161 tttcttcagc cttgtctgca acctcttgag cttgctcttc aggcttgttc ttgcttgttg
     8221 tttttacaaa atcattactt tcaaaccatt cttgtttcat ggtagaacct ccttttggtt
     8281 agataaatat gcttccatag tagcagatgt aagcgttttt gtcaacgtct gcttggtgtg
     8341 gatattagat caatattatc atcagatctc gcaatgagtt gatccttgac atcggttttt
     8401 tcagttttgt aagggttgct taattccgta cctcttgatt caggcttttc tcttgtgaat
     8461 tggaagatag aaccgtagtt acttgagatg tcccagttaa ttcgttggct ttctttctgg
     8521 tctaggatga ttctgagata atctttggca gtcagttcaa ccttaccatg gacttggata
     8581 ttttcagcgt ggaagtgatt atctgttgac tctagctgac tatctgtaag aactgtatca
     8641 aagatattaa cgatattggg cgttgtgagt ttactgtttt tgatacgact tccttcaatt
     8701 cggaggatat agctgtttgt attgagggtc gcattttcaa ggctagcatt tatgatggtg
     8761 gtttgtccgc gattggctga gatgttgatc ccttttagag ttctcccttt tggtagtcgg
     8821 agaataactt cttcaaaacg actagagtag ctacttgcga tatgaagaat cccaccaatt
     8881 ccagaagaga gaaacggagt ttcagacagt ttcttatcag tgagactcag agttctatcg
     8941 ttctgattgg tgataaaatc atggtgagca gaaagagatg gatggtaaga aatgtggatt
     9001 tgatcatcga aagagtctgt gatggtgagc gtgtgttggt ggagagtaat ttctaggttt
     9061 tcgacttcct tgccaaaggt tagcttttcc gtacggctat catagacagg ttctttggac
     9121 atggaaagta ggctcttaat cccgtcagat tggataccta caaaaagcag gataaagccg
     9181 ataacggtag tcaccacacc aaagatgaga aatccttttg tccatttacg catgctgatt
     9241 acctctcttt ccttttttaa gaacaaattg taccagacga acaatgagta gaccgaagaa
     9301 gcgagctaca taggaaatgc caagtaaaac tagcgaagaa gcaccgatag ccagtaaacc
     9361 agaaccaaaa atcaagataa aggctgattt ggcttgggcg aggatagtga aactttcaac
     9421 taaaaatagg aatccgccga tgatacccag tatggaaact gcaaagaaag ccagaatgac
     9481 agtcaaagcg gctacaagga ttgcgaacag ggtcacgagg atggcgattc ccagaggaat
     9541 gccgataggt gctgcaagga gggctaacaa ggcgatatgt aaaatttgtc ggttattttt
     9601 ttgagcgggt gcttcattga tttttttatc gagaagattg gatagaactt cgtgggccgc
     9661 ttctttggga gttcccaaac tagcgatgag ttcttcttct ccttcgactc cagcatcgtc
     9721 aaagagctct ctgaaatagt ccatggcttc gatacggtca gcttcaggta gtttcttgag
     9781 atagagttct agctgagtca ggtattcagt tcttgtcatg gcggatactc ccttctatga
     9841 tgccattgat ggtgtctgta tagagtgtcc attcatcttt tagggtcaag agctgctcta
     9901 taccaccgtt tgtcaaggag tagtatttgc gcatgcgacc ttggaactct ctagaatagg
     9961 ttgtcagaaa gctattgcct tccaattttt tgagaatggg atagagtgtg gattctttga
    10021 tattagcgat cagcttaatg gtttggctaa tctcataacc ataagaatca ccctgctcca
    10081 gtacagccaa gatgagaaat tcaatcaagg cagaggatgt tggaaagtac atgggaaacc
    10141 tccttttcta atgtgtaaga tttttatata taatttttct acacatacat tgtacatcta
    10201 aaagaaagcc ctgtcaagag aaatgtgtaa aatttttata tataaaaaac ttctagctaa
    10261 aactagaagt ttaaaggatc ttatccgctc tgtccactgt aaagagggcc acagtcatca
    10321 ggatatagat gagcaagagg gcagctacag ctggtaccca agagtggaac aggtcaaaac
    10381 tgtaaccaaa gagggttggc ccaaaggctg ctaggatata gcctcctgtt tgagataggc
    10441 cggacaattg ggctgtcttt tcaggggcgc ttgtcttgag tgaaaagttg accatgagat
    10501 aagggaagag ggcgctggtt gcggttccga tgaggagatg gatggtaagc cagtaaatga
    10561 aattattgat tgggaaaaag agcatggaaa tgccgaccac accagctagt gaaaccagag
    10621 tgagcatgag ctgacggttg cgagtagata aactggttgt caggcttggg atggtcattg
    10681 aaaaaggaat gctaatcaga gataagatag aagtcagcaa gccagcttcg tgactggata
    10741 gacctgcatg gatagacatg gtaggtaacc aggtcatgac ggtgtaaaag atcaaggatt
    10801 gaaaacctga aaagataata attgcccaaa cctgtttatt acgcatgacc tttatttgac
    10861 ttttttgttt ggtttgtgga gctagtctat gattatagcg gtgatttggg agccagacca
    10921 aaaaagttgc tagacagagt aacgtgagga ggaggataag tcctttccaa gaactggctt
    10981 gtgtaatggg cacagctaga taggaagcca gagccgttgc aatccccata gacgttacat
    11041 ataaggtggt cagaaaacca attttctttg gttgattggc ttggataaga ctaggaagca
    11101 ggacattgat gactgcgaca cttgccccaa ccatcaaggt tcctagatag agcaggggca
    11161 gattgattag tcgaatgagt gagccgatgg tcaagaagaa gaggctgtag gtgaagagat
    11221 gctccaagcc gattttctga gccagtcggg tagaaaatgg tgaaaagagg gtaaacataa
    11281 ggagaggcag gctggtcaag acaccaagcg aactaacttc tacctccaga ccttgcgaaa
    11341 tatttcccaa aataatgggt aaaacagtaa aaggagttcg caaggaaaca ccaatcagga
    11401 taatacctgg aacaaaaaag agtgattgct ttttcatata atacctcttc tagctgattt
    11461 taataacagc ttattttaag gctttttcac tataatgtca agtaaggttt ctggctttca
    11521 agataaaaat gggaaagtct tgaaaattat gatagaatgg tggaaggaaa aattcaggag
    11581 agtagtagtg actcaaaatg ttgaaagtct tctcgtatcc attgtaatca gtgcatacaa
    11641 tgaagaaaaa tatctgcctg gtctaattga agacttaaaa aatcaaactt atcctaaaga
    11701 gaatattgaa attctattta taaatgctat gtccacagat gggaccacag ctatcattca
    11761 gcaatttata aaggaagata cagagtttaa ctcaattaga ttgtataaca atcctaagaa
    11821 aaatcaagct agtggtttta acctgggagt taaacattct gtaggggacc ttattttaaa
    11881 aattgatgct cattcaaaag ttactgagag ttttgtaatg aacaatgtgg ctattattca
    11941 acaaggtgaa tttgtctgtg gggggcctag accgacgatt atcgaaggaa aaggaaaatg
    12001 ggcagagacc ttgcatcttg ttgaggaaaa tatgtttggc agtagcattg ccaattatcg
    12061 aaatagttct gaggatagat atgtttcttc tatttttcat ggaatgtata aacgagaggt
    12121 tttccagaag gttggtttag taaatgagca acttggccga actgaagata atgatattca
    12181 ttatagaatt cgagaatatg gttataaaat ccgctatagc ccaagtattc tatcttatca
    12241 gtatattcga ccaacattca agaaaatgct gcatcaaaag tatttaaatg gtttgtggat
    12301 tggcttgaca agtcatgttc agtttaagtg tttatcatta tttcactatg ttccttgttt
    12361 atttgttttg agtcttgtgt ttagtctagc attgttaccg atcacattcg tattcataac
    12421 tttactatta ggtgcctatt ttctactttt gtcactactc actttgctga ctttattaaa
    12481 acataaaaat ggatttctaa ttgtgatgcc ctttctttta ttttccattc actttgctta
    12541 tggctttggg acgattgtag gtttaattag aggatttaaa tggaagaagg agtacaagag
    12601 aacaataatt tatttggata aaataagcca aataaataaa aatatgctat aataacaata
    12661 tagtaaaact cttttaagga ggagtagatt tctatgaata aaaaactaac agattatgtg
    12721 attgatctgg tggaaatttt aaataaacaa caaaagcagg ttttctgggg aatatttgat
    12781 attttcagta tggtggtttc catcattgta tcttatattt tattttatgg gctgattaat
    12841 ccagcacctg ttgactacat tatctatacg agtttggcct tcctgttcta tcaattgatg
    12901 attggttttt gggggttgaa cgcgagcatt agtcgttaca gcaagattac ggatttcatg
    12961 aaaatctttt ttggtgtgac tgctagcagt gtcttgtcat atagtatctg ttatgccttc
    13021 ttgccactct tctccatccg tttcatcatt ctctttatct tgttgagtac cttcttgatt
    13081 ttattgccac ggattacttg gcagttaatc tactccagac gcaaaaaagg tagtggtgat
    13141 ggagaacacc gtcggacctt cttgattggt gccggtgatg gtggggctct ttttatggat
    13201 agttaccaac atccaaccag tgaattagaa ctggtcggta ttttggataa ggattctaag
    13261 aaaaagggtc aaaaacttgg tggtattcct gttttgggct cttatgacaa tctgcctgaa
    13321 ttagccaaac gccatcaaat cgagcgtgtc atcgttgcga ttccgtcgct ggatccgtca
    13381 gaatatgagc gtatcttgca gatgtgtaat aagctgggtg tcaaatgtta caagatgcct
    13441 aaggttgaaa ctgttgttca gggccttcac caagcaggta ctggcttcca aaaaattgat
    13501 attacggacc ttttgggtcg tcaggaaatc cgtcttgacg aatcgcgtct gggtgcagaa
    13561 ctgacaggta agaccatctt agtcacagga gctggaggtt caatcggttc tgaaatctgt
    13621 cgtcaagtta gtcgcttcaa tcctgaacgc attgtcttgc tcggtcatgg ggaaaactca
    13681 atctaccttg tttatcatga attgattcgt aagttccaag agattgatta tgtacctgtg
    13741 attgcggaca ttcaagacta tgatcgtttg ttgcaagtct ttgagcagta caaacctgct
    13801 attgtttatc atgcggcagc ccacaagcat gttcctatga tggagcgcaa tccaaaagaa
    13861 gccttcaaaa acaatatccg tggaacttac aatgttgcta aggctgttga tgaagctaaa
    13921 gtgtctaaga tggttatgat ttcgacagat aaggcagtca atccaccaaa tgttatggga
    13981 gcaaccaagc gcgtggcgga gttgattgtt actggcttta accaacgtag ccaatcaacc
    14041 tactgtgcag ttcgttttgg gaatgttctt ggtagccgtg gtagtgtcat tccagtcttt
    14101 gaacgtcaga ttgctgaagg tgggcctgta acggtgacag acttccgcat gacccgttac
    14161 tttatgacca ttccagaagc tagccgtctg gttatccatg ctggtgctta tgccaaagat
    14221 ggggaagtct ttatccttga tatgggcaaa ccagtcaaga tttatgactt ggccaagaag
    14281 atggtgcttc taagtggcca cactgaaagt gaaattccaa tcgttgaagt tggaatccgc
    14341 ccaggtgaaa aactctacga agaactcttg gtatcaaccg aactcgttga taatcaagtt
    14401 atggataaga ttttcgttgg taaggttaat gtcatgcctt tagaatccat caatcaaaag
    14461 attggagagt tccgcactct cagtggagat gagttgaagc aagctattat cgcctttgct
    14521 aatcaaacaa cccacattga ataaaaaaga aaaacgcata gtatcaagtt acacaacctt
    14581 ggtaatatgc gttttattat gtagagactt atactcttcg aaaatctctt caaaccacgt
    14641 caacgtcgcc ttgccgtatg tatatgttac tgacttcgtc agttctatcc acaacctcaa
    14701 aacagtgttt tgagctgact tcgtcagttc catctacaac cttaaaacag tgttttgagc
    14761 agcccgcagc tagtttccta gtttgctctt tgattttcat tgagtattac ttcattttct
    14821 tctgaaatag agttgtcgcc cagtctatgc tattgaaaat acgccaaaac ttctaagggt
    14881 ttgtgagcga tataatcagg ttgatagttt agtagatctg cttgctctcc aaatccccaa
    14941 gtgacggcca atttctgaat acctgtttct cgagctccca gcatatcaaa cttggtatct
    15001 ccgatgatga tggcttgttc tggtgctagt tgatgtgtct gtaaggcttg gtgaatgaca
    15061 tctgccttat ggggtgcttc agggctagaa ccataaatac catcaaagaa atgatggatt
    15121 tccaagtttt tggccatgtc ttgagcagta gatgtattct ttgtcgtggt gatgtagagt
    15181 ggataactgc tcgataactc ctcaagcaag tctataatct gaggaaagag ttgagcttca
    15241 tagatgcctt ttgccttata gtaagaacga tatatctgca tggcttcaga aatttggtct
    15301 ttggacaggc aggtcgcaaa actactttcg agaggtggtc ccataaaacc acgaatagtt
    15361 ttggcatcag ggctaggcac ccccagctct ttaaaggtat aggtaaaggc attgtgaatc
    15421 ccgatagaac tatcaacgag ggttccatcc aaatcgaaaa aaatcgctgt gatagaggtc
    15481 atggtttctc ctatttgata agcttattct ccgaaaatct ctttttggag gcgacgacca
    15541 gtaggggtgg tagcgagtcc accttcagct gtttcacgaa aggcagttgg catgcttgct
    15601 cctacttggt acatggcatc gatcacttca tccacaggga ttttagattc gatacctgcc
    15661 aaggccatgt ctgctgcgat gaaagcaaag ctagctccca tggcattacg tttgacacag
    15721 ggaacttcga ccaaacctgc aacagggtca cagatgaggc ctagcatatt tttaatgaca
    15781 aaggcaatag cttgactggc ctgataaggt gttccacctg cagccagagt caaggcggca
    15841 gcactcatag cagaggctga accaacttca gcttgacatc caccctcagc acctgagatg
    15901 gaggcattgt ttgcgatgac tagtccaaag gcaccagcag caaagaggaa atccaattgt
    15961 tgctcgtggc tgaggtctaa tttttcaata gcagcagtga gaacggaagg gagacaaccg
    16021 gcacttcctg cggtaggagt agcgcagacc aagcccattt tagcattgtg ttcattgact
    16081 gcgatagcat ttcgggcagc agagagaatc gtgtaatctg ataaagtttt ttcgtttttg
    16141 atgtagtgat ccaatttggc agcatctcca cctgtcaggc cactacgaga tttattttca
    16201 ttgaggccaa gttggacaga ggctttcata acttccagat tgcgttccat gagaaggaag
    16261 acttcttcac gttcgcgacc ggtcaattca aactctgttg taatcatgag ttctgcgaca
    16321 tttccttgaa agtccagatc tgcttgctcg accaattctt tgatagaata aaacatgctt
    16381 cctcctattt aaagaaattg acattgtgga gatgagggat ttttcgaatt tcttcgatag
    16441 cctcatcaca gttgcgactg tcaacttcga taatcataat ggctttttca ccagcttttt
    16501 cacgagtgac attcatctgg gcgatattga taccatagcg ggaaagcgcc tctgtaacaa
    16561 gggcaatcat acctggaata tcttgatgaa cgatgatgat agtcggtgta ttcatattga
    16621 gagagacggc aaaaccattg agttcggtta cctgaatatt tcctccaccg atagaaatac
    16681 cagtcacgct gatggtcttg tgggcatttt taacagtaat tttagtggtg ttagggtgag
    16741 gggcattgct gtctttctga atggtccaga caatcttgat accacgcttg tgggcaattt
    16801 ccagactatt tggaatttca ggatcatctg tatccattcc taaaatacct gcaacaaggg
    16861 ctaggtctgt tccgtgacca cgataggtct tggcaaatga gttaaaaagt tggaattcaa
    16921 cttctgtcgg agtatcatca aaaatggaag agacaatctt cccaatacga acagcaccag
    16981 cggtatggct actagatggg ccaatcataa ctggtccgat gatatcaaag acagattgaa
    17041 aacgaagtga tttcatcagt ttccccttat aaaaattctt atctctatta tatcaaagaa
    17101 tgaggggctt ggctttaatt gtggatgaaa acctttctaa tacctcaaat agcataaaaa
    17161 tagtatcttt tatgacaaaa aacaccttat ttagggaaat aaaaaataat tttgtaatat
    17221 ttctacataa aagtgtcaag aaacggtaat atttaaaggg tatgatagaa ctatagaaag
    17281 aaggagaatt ttcgaatatg aaatcaataa ctaaaaagat taaagcaact cttgcaggag
    17341 tagctgcctt gtttgcagta tttgctccat catttgtatc tgctcaagaa tcatcaactt
    17401 acactgttaa agaaggtgat acactttcag aaatcgctga aactcacaac acaacagttg
    17461 aaaaattggc agaaaacaac cacattgata acattcattt gatttatgtt gatcaagagt
    17521 tggttatcga tggccctgta gcgcctgttg caacaccagc gccagctact tatgcggcac
    17581 cagccgctca agatgaaact gtttcagctc cagtagtaag tgaaacagtt gtttcaactg
    17641 taagcggatc tgaagcagaa gccaaagaat ggatcgctca aaaagaatca ggtggtagct
    17701 atacagctac aaatggacgt tatatcggac gttaccaatt aacagattca tacctgaacg
    17761 gtgactactc agctgaaaac caagaacgtg tagcagatgc ctacgttgca ggacgttacg
    17821 gttcatggac tgctgctaaa aacttctggc ttaacaatgg ctggtattaa gaactaacga
    17881 acaaataata tgtaaaaggt cgaggagctc cctcgacttt ttttataatt tctttggttg
    17941 ataatgggtc tctacttctt ttttgagatg agacagcata gaagtttcct cggtcagctc
    18001 cagaagtgag aaaccttttt ggataagttt agcattatct gtacaaatcc caatacggac
    18061 atagcagata gcaagcctat cgtagctttt cttattcttg gcgtcctcca gtaaagtgta
    18121 gcagatttgc ttacacatgt ttttatcttg attgtataga tagagtgtgg aaaggtttag
    18181 caggattgct attcgcaagt catataaatg ttgatagttt ttatagactt ctaagcgttg
    18241 caagattttc tcggattatt gacaaataaa cggacattct gatagacgat tgccctagcg
    18301 gcttagtgta aactttacaa atttggcttg taattttttt ataaaattca cttcagttac
    18361 ttgacagtta ttatattttc gcttattata tagataaaag gatgggatag gattttaaaa
    18421 atttgaaagc gctatccata ttgtttattg gactgattct tgagtaatag ttagagtgtg
    18481 cttaatacta ctctggttgt tcaaggacct gatacagaag cgcaccattc tcccggttaa
    18541 gagtaagttc gttgttaaaa aatgaaatga gatagaagga aggtgagtcc aatggactac
    18601 gatacttgtt gataaattac tatagctgtt tttacggaac agctctcgat aataggagaa
    18661 ataaatcatg agaaaattag ttaaaattgg tgttgcatct ttaatggtat gtggtatact
    18721 tgctactaca aatgctttag cagtatgggt tgagggtggt caatggaact atggagtagg
    18781 ttggacagga acttttggat attctgatta cttacattct actcgatatc atacagcaac
    18841 tgttagacat gggggtagaa cctctaagga ttatgcaaaa cctgaggcat gggctagagc
    18901 ttccctcacc aagattccgc caacaggaat ggaatatttc tatggatttg agtaaaattc
    18961 ttccctctcc tatttggaga gggaaaactg tagtggaggc acttttatga aaaaaatcag
    19021 taatttctgt atgttactcc tgcttctgtg taccactttt tttgttttta atgtaaacta
    19081 tacacgagaa gtggttcgga ttcaagaaat gggaaagact gtagattctt tggatttgta
    19141 tttgaaagat attaacgaac ctgcagcgtc tgttcttcga ttttttgagg atgtatcaaa
    19201 ggagtataaa gtctccatca tcaaaacaga cagtggtgat gaggtggtca agtctggtgt
    19261 ttttgataaa gataccttcc cctaccaaga gtttgggatt tcttctcttg attttaccac
    19321 agatggtgaa ggagtctata gtaataaaga aatttccaat aaacttggta cgattccgac
    19381 ctttctaaaa gccaaaccta ttcagcttat gacttttcaa acctatatca aggatacatc
    19441 tcgtagttta aatggtcgct atacgataac ttctacacaa gagatggaca aggataggat
    19501 tgtacagaaa tggagcgatt ttttcaagat agaccaggct accttgctag agccgaccta
    19561 caaaagtgca gtggaagtca taaatcgaga tttgctttta tctgccattg tttttgtctt
    19621 ggctattttg cttcttgtgt tagtgacagt gtatcaaccg atgatggaga tgaaaagagt
    19681 tggggtacaa aaattacttg gttttcaaga tagggctgtt ttagctgatg ttgtaaaagg
    19741 caacctttac ctcctcctag gtggggctct tgtgatcaat ctaggcgtgt ttttcttgct
    19801 tgattataag ccaaaagatt tgtttcctat gctgtggttg tctcattttt tgctgttgca
    19861 gctttatctc tttatcagtt ggttgactta cctcttaatc caaaaaatga caatcagctc
    19921 tctgctgaaa ggtttttcat ctttcaaatt tggtcttatc ttcaattatg tgatgaaaat
    19981 agggacaact attttactga cggccttact gattggggtg ggcagaagtt tagaacaaga
    20041 aaacaaagaa cttgcttatc agcaacagtg ggtaagtcaa ggtaattacc tgaccttaga
    20101 aaccttcaaa ctcaatgata atctgtggca agaagagcta gcagggtcag ggaaatctac
    20161 agattatttc tatcgatttt atcaggattt ggtagaaaaa acgcaggcgg gctatgtgca
    20221 gagtagcagt cttcctgtaa aaaattttgt ccaatcagaa cagattcagc aatatcagtt
    20281 aacagatacg gtggatgttt actatgccaa tcgcaatttt ctaaagagca agggattcaa
    20341 gctaccagat accggtatta aaaaagttat tttgatgcca gcaagtacga aaggtgaaga
    20401 agataaaaat cagctcttgg ggaagttaat tgcctttcat tcgatgaagt atgaagagca
    20461 gcaaaaacga acgatagagg agatggatgt cgagattgcc tattatgaag gagattggtc
    20521 atttttccca tatagtgata agcgaaagga aaatctctcc aatccaatta ttagcttggt
    20581 caatgattct gatatgatgt gggatgagaa agcctccctg tcaacaactg gcttaaataa
    20641 tccgattaaa attgaaaata cggttcaaca tcaaaaagag attacagagt tagttgagaa
    20701 attgtcagat ggaaattatt taaaattttc atctattcaa gccattcaac aagagaaagt
    20761 ggattcttat cgagatgctg ttcggaattt taacctactc tttgctttgt ttggtctcct
    20821 tagcatgatg atttcctact tcttactagt aacaactttc ttattgaagc gcagggatat
    20881 cattaccaag aagtttatgg ggtggaaact ggtcgatcgc taccgtcctc tcctcgttct
    20941 gctcttgctg ggctatagtt tccctcttct agtcttgatt ttctttgccc atgcgttctt
    21001 accacttcta ctgtttgcag gttttacatg tctggatata ctatttgtgc taggcttagc
    21061 ttctaggatg gagaaaagaa gtctagtaga gttattgaaa gggggcatct tatgattgag
    21121 ttgaaaaata ttaccaaaac cattggggga aaagtgattt tggataactt atctctcagg
    21181 attgatcagg gggatttggt agctattgtt ggtaagagtg gtagtgggaa gtcgaccttg
    21241 ttaaatttat tgggtttgat agatggtgat tatagcggac ggtatgagat ttttggtcag
    21301 acaaatctag cggttaattc tgctaagtcg caaacaataa tccgtgaaca tatctcttat
    21361 ctgtttcaaa attttgccct gattgatgat gaaacggtcg agtacaatct catgctggcg
    21421 ctgaaatatg tgaaattgcc taagaaagac aagctcaaaa aggtggaaga gattttagag
    21481 agagtaggtt tgtcagctac tttgcatcaa agggtctccg agttgtctgg gggcgaacaa
    21541 caacgaattg cagttgctag agccatctta aaacccagcc agctgatttt agccgatgaa
    21601 cctacaggtt cgctggatcc tgaaaataga gatttggtct tgaagtttct cttagagatg
    21661 aatcgagagg ggaaaacagt cattatcgtg acccacgatg cttatgtagc ccaacaatgt
    21721 catcgaatca ttgaattagg cgagggaaaa tgagttcgtt cagcttcatt tgaccgactg
    21781 aatactcata tttttcagag agaaatagca taaataggcc taggaatgat atttttatgt
    21841 cattttcctg ggtttttctg ttttaaattg aaaaaaaata caatttaggc ttgacaaagg
    21901 atgagtatag gagtattatt tatacaataa aaaagaataa acataaagga ggctttgtta
    21961 tgaataagat gaagaaggtg ttgatgacga tgtttggttt agtgatgctc cccctactat
    22021 ttgcttgtag taacaatcaa tcggctggaa ttgaagccat caagtccaaa ggaaaattgg
    22081 ttgtagccct caatccagat tttgctccat ttgaatatca aaaagtggtt gatgggaaaa
    22141 atcagattgt gggttcagat atcgaattag ccaaggctat cgcaacagaa ctaggtgtcg
    22201 aattggaact atctcctatg agttttgaca atgtactggc tagcgttcaa tcaggaaaag
    22261 ctgaccttgc catatcaggt gtttctaaga cagatgaacg gagcaaggtg tttgattttt
    22321 caactcccta ctatactgca aaaaataaac tcattgtcaa aaaatctgat ttagccactt
    22381 atcagtctgt caacgatttg gcgcagaaaa aggtcggagc gcagaaaggt tcgattcaag
    22441 agacgatggc gaaagatttg ctacaaaatt cttccctcgt atctctgcct aaaaatggga
    22501 atttaatcac agatttaaaa tcagggcaag tggatgccgt tatttttgaa gaacccgttg
    22561 ccaagggatt tgtggaaaat aatcctgatt tagcaatcgc agacctcaat tttgaaaaag
    22621 agcaagatga ttcctatgcg gtagccatga aaaaagatag caaggaattg aaagaggcag
    22681 tcgataaaac cattcaaaag ttgaaggagt ctggggaatt agacaaactc attgaggatg
    22741 cctttaaagc gtccattgaa aaatagaaag aaggaaaaga acatgagtaa agaaaaagta
    22801 attttggcct attctggcgg tttagacaca tcagttgcta ttacctggct gaagaaagac
    22861 tatgatgttg ttgcagtttg tatggatgtg ggtgaaggga aagacttaga tttcatccat
    22921 gataaggctc ttaaggttgg ggcagtcgaa tcttatgtca ttgatgttaa ggacgaattt
    22981 gctacagatt atgtgctagt agctctccag tcacatgcct actatgaaca aaagtacccc
    23041 ttggtatctg ccttgagccg ccctcttatt tctaaaaaat tggttgaaat agcgcatcag
    23101 acaggagcga ctacaattgc tcatggttgt acaggtaagg ggaatgacca agtacgtttt
    23161 gaagtatcga ttgcagcctt ggatctcaat ttaaaagtga ttgctccagt tcgtgaatgg
    23221 aaatggtctc gggaggaaga aatttattat gccaaggaaa atggggtgcc tgttcctgct
    23281 gaccttgaca atccctactc tgtcgaccaa aatctttggg gacgtgccaa tgagtgtggt
    23341 attttggaaa atccatggaa tcaggctcca gaagaagcct ttggcatcac aacttctcca
    23401 gagcaagctc cagatatgcc agaatacatt gagattgagt ttagtgaagg tgttccagtt
    23461 tccctcaatg gagaagtgtt aaaattggca gatttgattc aaaaactcaa tgaaatagct
    23521 ggaaaacatg gggttggacg gattgaccac gtggaaaatc gcttggttgg gattaaatca
    23581 agagaaatct atgagtgtcc aggtgcagtg accctgctga cagctcataa ggaaattgag
    23641 gacttgacgc ttgtgagaga agtggctcat tttaaaccaa tcatagaaaa tgaattatca
    23701 aatctcattt ataatgcttt gtggtttagt tcggctacac aagccttgat tgcttatatt
    23761 aaagagactc aaaaagttgt caatgggact gcaaaagtca aactgtataa ggggagcgct
    23821 caggtcgtgg ctcggaaatc accaaattct ctttacgatg aaaatttggc gacgtatact
    23881 agtgcagata ccgttgacca agatgcggct gttggcttta ttaagttatg gggacttcca
    23941 accaaggttc attctgaggt tcaaaaaagc gccaaatagg acgattggat agagaggtgg
    24001 atgtgatatg gctaagaata caaaattatg gggtggtcgc tttggcagga acgactttcc
    24061 ccattgatcg ccaattgtct agcgatttgc tggagtttaa gcaaccttat acaaattctt
    24121 tggatgctgt tagtgaccgc gattttatct tagaatttct atcaaatgcc agcatactca
    24181 tgatgcatat gagtcgtttt tgcgaagaaa tgatcaattg gtgtagtttt gagtaccaat
    24241 tcattacctt gtcagatacg tttacaacag gttcctctat tatgccccaa aagaaaaatc
    24301 cagatatggc tgagttgatt cgaggaaaga ctggcagagt ttatgggcat ttgtttggac
    24361 tgttgacagt catgaagtcc ttgcctttag cttataataa ggatttgcaa gaagataagg
    24421 aaggaatgtt tgatacggtc gaaacgattt taaattccct cgatgtgttg gcaggtatgt
    24481 tatctagttt gcaggtaaac aaggaaaaaa tgcaagaatc aacagagaag gacttttcaa
    24541 atgcaactga gttggcagat tatttggcag ggaaaggctt gccatttaga gaagctcatg
    24601 aggttgtggg aagattagtg ctagactcta tcaagtctgc taaaaatctt caagattgga
    24661 ctttggagga attacaaacc tatcattctc tcattaccga ggatatctat gtctacttgc
    24721 aacctaaaac tgctgttcaa agacgaaatt ccttgggagg cacagggttt gaccaagtcg
    24781 aataccagat tgcagtcgct aagaaagcga atgaagctaa aaagtgatgg agtgatgggt
    24841 tcagaataag aggttggtcg attggcagcc tctttcttgt cgttgaaaaa gtgagatata
    24901 ttgacttttg aaaaaaatgt cataattgag ttgggataaa cgtaaaagtc atactttctc
    24961 gttaaatcgt tcggcgattc atggtgacat ggacacatag tagtaaacac actatgtggc
    25021 ttggcagagc taaaaacttc tggcttaaca atggctggta ttaagaacta acgaacaaat
    25081 aatatgtaaa gagtcgagga aatccctcgg cttttttatc tttccttcgc ttggtaatag
    25141 atctctactt cttttttgag atgagacagt atagaagttt cctcggttag ctccagaagg
    25201 gagaaccctt tttggataag tttcgcatca tccctacaaa tcccaatacg gacatagcag
    25261 atagccagcc tatcgtagct tttcttattc ttggcgtcct ccagtaaagt gtagcagatt
    25321 tgcttacaca tgtttttatc ttgattgtat agatagagtg tggaaaggtt taatagaatt
    25381 gtcattcgca agtcatataa atgttgatag tttttataga cttctaggcg ttgcaatatt
    25441 tttccagtga tgagatggag gtattcaatg ggaaaactga aaagaatggt attgaggatt
    25501 tttagatcac tctcatacca tgtatcttgt ttttcaattt ttttccaaag ttttttgaca
    25561 acctgttctg cgtgttttga tagttcccct gccccgtgtt gacggagata aataacaact
    25621 tcaagcatat ctctgatttc ttctataggg agatcgtggt gggtcttgag gtagtcttgg
    25681 catttttgaa ataaattgac aagatcgctg gtcccgataa tggaacgcat attgagatag
    25741 gtttgcataa tctctgtgcg ttgacttggt tgataaagtt gacagatata ttcaaactct
    25801 tcaaaactca tattgatttg acggagaaga aattccatat tttcatattt tggggttgtc
    25861 ttgccacttt cgatttttga taagctggtt cttgagagaa cacccccaca gacctcttct
    25921 tgggtcagcc cctttgactc acgtatttct ttatagacct ttccgaaatc ataacgcatg
    25981 attttctcct tttcgtgaaa aaagttaaca aacaataaaa ttttgttaaa aatattgtat
    26041 catagcaatg taaaaagtaa aaaagaaagt cgaaataaat ttgtgaaaaa agttaacgta
    26101 attttaaaat gagcttaata agaggtacta tgtaggtaga aaataaagat aggagaaaaa
    26161 gtatgaataa aaaaatattt tgtattctag tatgtattat atcattgatt agtctggcta
    26221 taatctttcc atggggctgg ccgatataat gtaagggagt ttgagttgtt aaaggaggct
    26281 cagtccttgg gcaaaaatct gctgtactac aatgcttgga aagatatcaa gaacaaagaa
    26341 tgatacggtt gaaaataaat taattcaaga actactgggc agtgattgag gtttgggtga
    26401 catcaaagaa aagttagatg aattctaaag aattgagtat ttctatgtta aaaaaatatc
    26461 cttgtacgat gcaacatgac cagtcagatt gtgctgcggc agttgtttca acagttcttt
    26521 tatcttacaa aaaggaacta tcaatcatga agattaggga aattattggt acagacatgt
    26581 atggaacgac tgtcagtggt attgtttcag gtctgaataa gttgaatttt acagtaaaag
    26641 ctgttcgagt agcactggaa gatttgactc caaaattaac atttcctgcg attcttcaag
    26701 ttaagaatga tttaggtcaa aatcattttg tggtattaca tagtatcaaa aggaatagta
    26761 aattttacgt agcagaccct gctagtggca tacgcaagat gtcaagtgat gaactgggag
    26821 aaatttatca aggtattact ctttttatgg ttccaaattc ggattttgaa agagggaaac
    26881 taaagggaaa aggacttctt gatttatttg gaaggttaat ttttaatcaa aaaggattga
    26941 ttagtacagt catattagct tcctttgttt taagtatcat tggtatttta tcgagtctct
    27001 tttcaaaagt tatcatggac gaggtgattc catatgcttt aaaaaatagt ctgtatatgt
    27061 ttttgatagt atttggaata gtgtcgttct tacagactct tctatctgca tttcgtcagc
    27121 acgttctttt gtttctatct cgaaaaattg atataccggt tttaatggga tattatgacc
    27181 atattattca tcttccttat agtttttttg gaagtcgtag agttggtgat gttttaacaa
    27241 gatttcaaga tgcgatgacg ataaagaatg tgtttacgtc agtctctatt tcattagtca
    27301 tggatatcat cttgtcagtt attagtgcgg ttgtcctttg gactattaat caatctttat
    27361 ttctgatatt agtttttatg gttattgtta acatcattct tatatactgt tttaaaaagc
    27421 cttataaaaa aattaatcat gaacaaatgg aagcaaatgg acttcttaat tcacagttaa
    27481 ttgaatctat tcgtaacatt gataccatta agtctcagca tgatgaggaa caacgtttaa
    27541 acaaaattga agaaaaattt gttcatactt tagaaattgg ttataaagag ggcgttttgc
    27601 agaatattca atctacaata tcttcaatga cctcaaccat gggtgggtta ttatttatgg
    27661 gagtgggcgc cttatttatc attgatggaa aaatgactat tggggacctc ttggtttttc
    27721 agacattaag tcaatatttt acagaaccta ttcagaattt agttggcttg cagttaacct
    27781 ttcaagaggt acaggttgcg gttagtcggc ttcaagaatt gatggaagta gatcgtgaag
    27841 acattgcctt ggattatagt attagagact tcaccttatg tgatgacatt gaatttaaag
    27901 atgtaacatt tgcctatggt tcacgccctc ctgttatcaa ggactttaat ttgcgaatta
    27961 aacaaggaga aaaaatagct tttgttggag aaagcggagc aggaaaaagt acgctagttc
    28021 gtttgttatt aagatttata aatccgagtg aggggaaaat tcgtatagga gaaaatgact
    28081 tatcagatct tgactatggt aaactacgta agaaaatttc ctacattcct caggccatag
    28141 aactctttac agggacaatt attgataatc taaaaattgg taatccttct gttacatatg
    28201 aggatatggt gagagtttgt cgtattgttg gtattcatga tacgattcaa cgtcttcaaa
    28261 atcgttatgg ctcctttgta gaagaaggcg gtcaaaattt ctcgggtgga gagaaacaac
    28321 gattggctat tgcaagagca ctactgagta aagctgattt gtatatattt gatgaggcaa
    28381 cctctaactt agattcattt agtgaacaga ttattcagga tttaatcttt aataaaataa
    28441 tagataagac aacaattgta gtagcccaca ggctgtctac aattcttcga tgtgataaga
    28501 tatgcttttt agaaaatggg actattgtgg aatatgggac tcatgaagaa ctaatggcga
    28561 aaaatggaaa gtatgctaga atggttggtt tgcagagcgt tcaagtgaat caacaaattc
    28621 agtcacaggc tgtgttagat atagaggagg ttacttatgg ctaagttaga ggtaaaagat
    28681 aataaaaaac tggtactaaa gtcagttatc tgtaaaaagt tacatgatac aaaagtagaa
    28741 gatgtagatc aggaaattaa taaatttcat caacatttgc agttgttaaa agcacaaatt
    28801 tttggtccat taattgtaaa aagttgtggt actactattc atgatgatgg attaataacg
    28861 actgattttg agttttatat tcaagctcat aatgctcaac agtacagtaa catttatgat
    28921 gtacaggatt ctatctctgt tccatattgt ttatatgttc gttttgaaga cagtccagag
    28981 tatctacagt atgcgtattc taaattggat ctatatgtct atgaaaatga tattcaaacg
    29041 gatgggattg tctatacagt ttatgttaat tcttctcctg aaaaaatggt agtagatatt
    29101 tttagaccaa ttgtaagcct atgaaattat ataataaatc agaattacgt tattctcgta
    29161 ttttctttga taagagacca ccagcttttg cgtttattct cattatttca actgctatta
    29221 tcttaagcgg tgcattggtt ggcgcagctt atatacccaa aaactatatt gtaaaagcga
    29281 atggaaattc agttataaca ggtacagagt tcctatcagc aattggttca gggaaggtag
    29341 ttactttaca taagtcagaa ggagatatgg taaatgctgg agatgtcatt atttcgttat
    29401 caagtggaca agaaggttta caagcgagct ctttaaataa acaattggag aagttacgtg
    29461 caaaagaagc tatctttcaa aaatttgaac aatcattaaa tgagaaatac aatcatttat
    29521 ctaattctgg tgaagaacag gaatattatg ggaaagttga atactatctg tctcagttaa
    29581 actcggaaaa ttataataat ggtacccagt attcaaagat tcaggatgaa tatacgaagt
    29641 tgaataaaat aacagctgaa agaaatcagt tagatgccga cttgcaagct ctacaaaatg
    29701 aattgcttca acttcaacag caaggagact caccttcttt atcagatacg acatcagctg
    29761 atgataaagc taagttagaa actaagatat cagaaataac aacaaaaatc gaagcattaa
    29821 aaacaaatat tacttctaag aatagcgaga ttgatagtca acaaagcaat attaaggata
    29881 tgaaccgtac ctataataat ccaacttctc aggcttataa tatttatgct caattaatta
    29941 gtgagttagg tactgctcgt tcaaacaaca ataaaagtat tacagagctt gaggctaatc
    30001 ttggagtggc aacaggtcaa gataaagcac atagtatatt agcgccaaat gaaggtactc
    30061 tgcattatct ggtacctttg aaacaaggaa tgtctattca gcaggggcaa acgatagcag
    30121 aagtttcagg gaaagaaaaa ggttactatg tagaagcttt tgtacttgcg agtgatattt
    30181 ctcgtgtttc gaaaggagca aaagctgatg ttgctattac tggtgtaaat agtcaaaaat
    30241 atggaacact aaagggacaa gtcagacaga ttgattcagg aacaatttcc caagaaacga
    30301 aagaggggaa tattagcctc tataaagtca tgatagaatt agaaacctta actctaaaac
    30361 atggaagtga gacagtcgtc ctccaaaagg atatgccagt tgaagtgcgg attgtctatg
    30421 ataaagaaac ctatcttgat tggattttag aaatgttaag tttcaagcaa taattggttt
    30481 taaacccctt aggtaaccta taaaaataaa taaggtagag aaaggatatc ttatctaggt
    30541 agctaagtga tagaaacaca gtcgacgatt acttgttagg aaactatcct aaccatgctt
    30601 aataaaaaag gagaaaataa atggaactca tattgccaaa taattatgtt gatcttgaac
    30661 aagaagagat gatgtatctt gatggcggag aaccaatgtc aatttcggcc attgttgcct
    30721 tggctatcac aattggtggc gcatcgtata gcacaggata tgtgttagga gaaagagtct
    30781 actattcagg atataaaaac tctgattatc aaaaaaataa gtggggtatt aggggagcaa
    30841 tgctggctgc atttggagca ataggtgcag tagttatgct cggttttgaa aatagatact
    30901 atgctttggt tactggtaga ggataaaatg ttaagagtaa tagtagttat tcaatcttta
    30961 gtaataatac tgcttgctgt tgctttatta ttatctcgga aaaactttga ttcgttaaat
    31021 gttgttctta taatgatgat cgtatcacaa ttgttgttat tagtatattt gataaaatta
    31081 gggaatcagt gattagctgt tatttgaatt aagtaaactg ttaagcttca agcagtaact
    31141 ggttttaaat atttaaaata agataaagga aggaagtcta atttaggtaa ctaaacaaag
    31201 cctgcgatca cttgttagga aactatccta accatgctta ataaaaaagg agaaaataaa
    31261 tggaactcgt attaccaaat aattatgttg ctcttgagca agaagagatg atgtatcttg
    31321 atgggggagc ttatttaagc aagcgtgctt gtcaaggaat ttgcgcagct ttagctatga
    31381 gtccaggaac ttttatagca ttagctggag ctgcagtttt aaccaaaaaa ctaataaact
    31441 atattaaagt tggaggcctt ggaggttggc ttattggtgc agcagcaggt gtattggctg
    31501 gggcggcagg aagaatagct tactgtattg gatatggtgc tcttaataga ggttgtgata
    31561 ttagcgggaa cccttatcct tgggatggat tcatatctgc gacagtaaga tgagtaatgt
    31621 agataagatt cgaaaaatac acattatcgt atgttggatg tatatatttt tatcattcag
    31681 ggcgattata aatgacacgg agtatttttt gcttattttt ttagctttta tctactcaat
    31741 agtatcacta cctctatatt ctgtgaaaaa taaaatagta tctatctgtc tagccataaa
    31801 ttcgattctg ttaatgagtt tccccatttt aatcaataag tttttcccag aaagtttttt
    31861 gacttatacc gtattaataa gtgtttttat tacagagttg ataatttttc atttaattgg
    31921 gaaagatttt gatattaaat tgactaacga atataagaaa attagtcagt ttagaagcaa
    31981 ggtgtctcaa tctccttgga taaaatattt agagatttct agttttatat taactatatt
    32041 tccatctatt ctttatggta cagttgataa tcatgtactg actcttatct ttttgataaa
    32101 aatttgtgca gataccacga taaaattttt attcatcaga ttatttgaca caagtacttt
    32161 aatgaagagg agaatatttt ttcttttcgc attggatgtt atagcttact tatttttagg
    32221 atatctttta gtgattcaaa aagcaggcta tttgttttcg gttttacttc ttttttctaa
    32281 tttttcagtt ccatttatca aagcaaagga atacgaatta tttaaaaata gcaagtaata
    32341 gaaacatagg ttaaatctta gaacggctta aaatcagata tgataaaggg aaatagtctt
    32401 atctaggtaa ctaagtgcta caaacacagt cgaggatcac ttgttaggat tacattttaa
    32461 tcatgcttaa taagaatgga gaattcctat ggggattgta ttactctgaa gtttcgaata
    32521 ccttagttct cgtgattttg agctgttcta gctttagaat ccttcagaat gtaaaatttt
    32581 aagcagtcaa agacttagaa tagcctggaa acatttattt tatagcaatt ctaggcttag
    32641 aattgctcat atatatgtat ttgagctgct cgatagttag gacagctcta ttctgagaaa
    32701 tctgagctat caatgcttca gaatagtatt tcgcaaatgg tttttattga agaggtgatt
    32761 gttttatgat agtctaaaat aaaactgatt taatggagta aatggagaat cgtcacatga
    32821 aacatttttt tgcaggaatt ggtgagataa aacttgttgg ctacttattg tatatatgtg
    32881 taggactagc ccctcttttt catatatatg tcataggttc ggaactgagt tttgtgaaaa
    32941 tagtgttatc tattttggga gttatatttg taagtatgtt aactattgct cgaatttatc
    33001 ggacttttct ataaagaata gtttggactt gaactgtatc taaaaacaga ggttggtcga
    33061 ttatcagcct ctttcttgtc gttgaaaaga gtgagatata ttgacttttg aaaaaaatgt
    33121 cataattgag ttgggataaa cctaaaagta atatagtaga ttgaatctgg aatagtccgt
    33181 tatgactgtt aaaatatttc tagaaattaa tttgactttc ctaatcgatt tgttcacatc
    33241 ttgtttcaat ctactatact ttctcgttaa accgttcggc aattcatggt gacatggaca
    33301 catagtagta agcacactat gtggcttggc agagctaaaa actgttccct tgcgataagc
    33361 ctaataagca caacataggg agttagagaa gccgactcta atcaaccact ttgggcagta
    33421 gtgagaactg ccccgtgctt ttttattttg agaaaatatg gagtttgtcg ttgaaattac
    33481 ttgattgtat tttggactat caagaaagat tcaatggaaa aacatgtcaa gtatcaacga
    33541 attataagta tttagagatt ttcaaagtga atttttgctt gactgattta catcatttat
    33601 ttgacttata caaaatcaca cgagattatg ctagtcaaac aaaacctgct attcaagctg
    33661 gtgtttttat tttagaagat tttagaaata tcctatgtac aatgatgtaa tcgaaaggat
    33721 atctttatat gagtttatcg gtgatatttt ctattctaaa ataataagtt gttgcatcgt
    33781 agctagggat ttatctaaaa atactatgaa attggacgtc atattttttg aggataaaaa
    33841 taaaagatcc gcagttttag gtttacgaag agacaaaagc ggagtattta aatcagttac
    33901 tctacatttt acaagcgcta agaaatatgc taaagttcgt aaaacagatg tgaaagaaat
    33961 gaaatggcta taaagattgt ccgcaggctt aagcttgcgt tttttgttgt ttaacgaaat
    34021 taaaaaataa gctctctcat tggaaatgtt tttataggaa tgaaggaaga tgatgctatg
    34081 tttaaaaaga gaatcgaaaa gggcaaaagt agtgtcttta tctttttgga gtagaagctt
    34141 atgatataga aatttgtaat aaaaatgtaa tataaaacat ttgacaaata tttacggggg
    34201 gagtatactt aatataagta tagtctaaaa atgactatca gaaaagaggt aaatttagat
    34261 gaataagaaa aaaatgattt taacaagtct agccagcgtc gctatcttag gggctggttt
    34321 tgttacgtct cagcctactt ttgtaagagc agaagaagct cccgtagcta gtcagtctaa
    34381 agctgagaaa gactatgatg cagcagtgaa aaaatctgaa gctgctaaga aacattatga
    34441 agaagttaaa aagaaagcag aagacgctca gaagaaatat gacgagggtc agaagaaaac
    34501 ggtagaaaaa gcaaagcgag aaaaagaagc ttctgaaaag atagctgagg caacaaaaga
    34561 agttcaacaa gcgtacctag cttatcaaca agctagcaac gaaagtcaga gaaaagaggc
    34621 agataagaag ataaaagaag ctacgcaacg caaagatgag gcggaagctg catttgctac
    34681 tattcgaaca acaattgtag ttcctgaacc aagtgagtta gctgagacta agaaaaaagc
    34741 agaagaagct aaagcagaag aaaaagtagc taagagaaaa tatgattatg caactctaaa
    34801 ggtagcacta gcgaagaaag aagtagaggc taaggaactt gaaattgaaa aacttcaata
    34861 tgaaatttct actttggaac aagaagttgc tactgctcaa catcaagtag ataatttgaa
    34921 aaaacttctt gctggtgcgg atcctgatga tggcacagaa gttatagaag ctaaattaaa
    34981 caaaggagaa gctgagctaa a
//
LOCUS       DAVLIK010000017        34654 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLIK010000017 DAVLIK010000000
VERSION     DAVLIK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34654
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.017"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            9..89
                     /locus_tag="VXE87_000947"
     tRNA            9..89
                     /locus_tag="VXE87_000947"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="VXE87_000948"
     tRNA            94..164
                     /locus_tag="VXE87_000948"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="VXE87_000949"
     tRNA            179..251
                     /locus_tag="VXE87_000949"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            262..333
                     /locus_tag="VXE87_000950"
     tRNA            262..333
                     /locus_tag="VXE87_000950"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:294..296,aa:Gln,seq:ttg)
     gene            343..426
                     /locus_tag="VXE87_000951"
     tRNA            343..426
                     /locus_tag="VXE87_000951"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:377..379,aa:Leu,seq:caa)
     gene            533..1810
                     /locus_tag="VXE87_000952"
     CDS             533..1810
                     /locus_tag="VXE87_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0842515.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VEERFSIYMEAIQKKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1886..3370
                     /locus_tag="VXE87_000953"
     CDS             1886..3370
                     /locus_tag="VXE87_000953"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0842516.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3431..4711
                     /locus_tag="VXE87_000954"
     CDS             3431..4711
                     /locus_tag="VXE87_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0842517.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4715..5335
                     /locus_tag="VXE87_000955"
     CDS             4715..5335
                     /locus_tag="VXE87_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0842518.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5501..6643
                     /locus_tag="VXE87_000956"
     CDS             5501..6643
                     /locus_tag="VXE87_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0842519.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDVQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAKKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVAERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7052..7390
                     /locus_tag="VXE87_000957"
     CDS             7052..7390
                     /locus_tag="VXE87_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0842520.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVETAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            7401..7769
                     /locus_tag="VXE87_000958"
     CDS             7401..7769
                     /locus_tag="VXE87_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV0842521.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            7876..8493
                     /locus_tag="VXE87_000959"
                     /pseudo
     CDS             7876..8493
                     /locus_tag="VXE87_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(8520..9377)
                     /locus_tag="VXE87_000960"
     CDS             complement(8520..9377)
                     /locus_tag="VXE87_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0842522.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9507..10649
                     /gene="tgt"
                     /locus_tag="VXE87_000961"
     CDS             9507..10649
                     /gene="tgt"
                     /locus_tag="VXE87_000961"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0842523.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLSSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            10750..12567
                     /locus_tag="VXE87_000962"
     CDS             10750..12567
                     /locus_tag="VXE87_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0842524.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12720..13871
                     /gene="nagA"
                     /locus_tag="VXE87_000963"
     CDS             12720..13871
                     /gene="nagA"
                     /locus_tag="VXE87_000963"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0842525.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14034..15092
                     /locus_tag="VXE87_000964"
     CDS             14034..15092
                     /locus_tag="VXE87_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0842526.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15243..15608
                     /locus_tag="VXE87_000965"
     CDS             15243..15608
                     /locus_tag="VXE87_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0842527.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15684..16625
                     /locus_tag="VXE87_000966"
     CDS             15684..16625
                     /locus_tag="VXE87_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0842528.1"
                     /translation="MVQEIAQEIIRSAREKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYGNLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16573..17589
                     /locus_tag="VXE87_000967"
     CDS             16573..17589
                     /locus_tag="VXE87_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0842529.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMKSLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17591..17653
                     /locus_tag="VXE87_000968"
                     /pseudo
     CDS             17591..17653
                     /locus_tag="VXE87_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGC"
     gene            complement(17671..19116)
                     /locus_tag="VXE87_000969"
     CDS             complement(17671..19116)
                     /locus_tag="VXE87_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0842530.1"
                     /translation="MITTNKVAIYVRVSTTNQVEEGYSIDEQKDKLSSYCDIKDWNVY
                     KVYTDGGFSGSNTDRPALESLIKDAKKRKFDTVLVYKLDRLSRSQKDTLHLIEDVFIK
                     NGIEFLSLQENFDTSTPFGKAMIGLLSVFAQLEREQIKERMQLGKLGRAKSGKSMMWA
                     KTSYGYDYHKETGTVTINPAQALTIKFIFESYLRGRSITKLRDDLNEKYPKHVPWSYR
                     AVRTILDNPVYCGFNQYKGEIYPGNHEPIISKEEYDKTQSELKIRQRTAAENVNPRPF
                     QAKYILSGIAQCGYCGAPLKIMLGVKRKDGSRLKKYECHQRHPRTLRGVTTYNDNKKC
                     DSGFYYKDKLEASVLKEISKLQDDADYLDKIFSGDNAETIDRESYKKQIEELSKKLSR
                     LNDLYIDDRITLEELQSKSAEFISMRGTLETELENDPALRKNKRKADMRKLLNAEKVF
                     SMDYENQKVLVRRLINKVKVTAEDIVINWKI"
     gene            complement(19500..20267)
                     /locus_tag="VXE87_000970"
     CDS             complement(19500..20267)
                     /locus_tag="VXE87_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0842531.1"
                     /translation="MKVENKEIFANNLSFYMEQKGVDRNTLCADLDLKYTTVRDWLKG
                     ITYPRIGKIELLANYFNINKSDLIENKIFTAQPSDSLLEEITNTARKLNTDNKKIVLR
                     TSEELLESQENEEETKINEVSENIIRLDDYRQTTYRRVTGVVSAGSGSIQDDDLDMEV
                     SFYEDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTQQVDYNTIGIFQVDGANYVKK
                     LRQGYLESLNPDYEDIHLDESNDIRTIGEVVSVYREK"
     gene            20429..20704
                     /locus_tag="VXE87_000971"
     CDS             20429..20704
                     /locus_tag="VXE87_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842532.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSQLEAFCTNCRQF
                     AFGWTELAEEIERQERYLLDSGFTQEEIDDIRFDVAFAGMLDKLNVA"
     gene            21298..21441
                     /locus_tag="VXE87_000972"
     CDS             21298..21441
                     /locus_tag="VXE87_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842533.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            21438..21608
                     /locus_tag="VXE87_000973"
     CDS             21438..21608
                     /locus_tag="VXE87_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842534.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAIEARLNQKADQLKLDDLD
                     LEIISSRLEKVI"
     gene            complement(21601..21840)
                     /locus_tag="VXE87_000974"
     CDS             complement(21601..21840)
                     /locus_tag="VXE87_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842535.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMANPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            21913..22119
                     /locus_tag="VXE87_000975"
     CDS             21913..22119
                     /locus_tag="VXE87_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001171134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842536.1"
                     /translation="MSKMTLKTLRTLKNWRQSDAAAAVNVSVDTWGHWERGITEPSVS
                     KAYQIASVFDVSVDDIIFLPDIAV"
     gene            22192..22554
                     /locus_tag="VXE87_000976"
     CDS             22192..22554
                     /locus_tag="VXE87_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0842537.1"
                     /translation="MQYIIRNTHGNYTSLNNAYAQDKRLKATTIGILTVILMNKSDWV
                     VYPDEIARRLGISRRTVDEHFKLLEKAGYLRVYRLGLGRGKGVTVYRFFSDMPISDDY
                     FEYLKTNLEKELSTDNGV"
     gene            23016..23732
                     /locus_tag="VXE87_000977"
     CDS             23016..23732
                     /locus_tag="VXE87_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEV0842538.1"
                     /translation="MNELINVTLNDNQEPVVSGRQLHEALGVNSRYTTWFDRMKEYGF
                     TEGQDFLPNLGKSTGGRQATDHIIKLDMAKEIAMIQRTERGKQVRQYFIQVEKDFNSP
                     EKIMARALLMADQKVHKLEAQIEADRPKVLFADAVSASHTSILVGELAKLISQNGYKI
                     GANRLFSWMRENGYLIKRKGSDWNVPTQRSMDLKLFEIMETNVQHADGHITVNKTPKV
                     TGKGQQYFINKFLNQEYLTG"
     gene            23804..23965
                     /locus_tag="VXE87_000978"
     CDS             23804..23965
                     /locus_tag="VXE87_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842539.1"
                     /translation="MKTVKKEWEPRIVNIMADGSQVDDLTGYVIPAGHSYYDIILGMN
                     KQSNEEGVA"
     gene            23965..24186
                     /locus_tag="VXE87_000979"
     CDS             23965..24186
                     /locus_tag="VXE87_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842540.1"
                     /translation="MKLLTKLKLRLEGVIKSVNLDWREVAIEVSNDLLEERKRRFMRE
                     QENHDLKQELAAYKYKENFDIKARLQGEM"
     gene            24187..24441
                     /locus_tag="VXE87_000980"
     CDS             24187..24441
                     /locus_tag="VXE87_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842541.1"
                     /translation="MYIISIYVKNTETGNEDFSLIGRDFLPTGHQDYIARVFGIKEEA
                     IDYLKSISYIASGVHGNDWVYQNEKLPEIESRCRIWKVGE"
     gene            24454..24714
                     /locus_tag="VXE87_000981"
     CDS             24454..24714
                     /locus_tag="VXE87_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842542.1"
                     /translation="MFKALKTIKKIKQLQKEMHDVSLAFLALQDVGLMPETERSKAKA
                     QTMHDVSHMLKDVLGGKSVDEAMKRLNSEVKIEEVEQEDDKD"
     gene            24939..25757
                     /gene="bet"
                     /locus_tag="VXE87_000982"
     CDS             24939..25757
                     /gene="bet"
                     /locus_tag="VXE87_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEV0842543.1"
                     /translation="MTNNQIVEAKGDFLTNPQLLNSGIIRKYLDPQGKASDEELAYFI
                     AQAKAQNLNPFTKEIYFIKYGTQPAQIVTAKSAFEKKADSHPQFDGKEAGVIYLMDGE
                     IKYSKGAFIPKGAEILGGWAKVYRKDRTYPTETEVSFEEYDNSKIRARVKELTQQGKD
                     VTYPVMNSYGKPIGENNWDTMPCVMIRKVALVSAYREAFPAELGASYEADEIQLDNTP
                     KDVTPQESREDVVARKMAQIEQFNKEQEANHADPEPAKTEEPIQGELLDGELEY"
     gene            25767..26855
                     /locus_tag="VXE87_000983"
     CDS             25767..26855
                     /locus_tag="VXE87_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV0842544.1"
                     /translation="MQELQVIDDKKINKIYEMITTDELTRESFEKDLIEATEKYKDYI
                     PTAGTLKDDKAKRAEFNKLIESKNRIRIDTKNLLSETANTWDSYAKSIIDPFATVVSE
                     FDKGIKEIEEHQRQLKIDTVKSYLANKSAEYMLDPRLFDEKALEYVKAGDFMADGVTL
                     KKATMKSLDDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEAFEQ
                     IKADYEFEKQKEEIRQAQERAERESQELLAAQQTKQQERAPKSTGTPNFDPEAGEILD
                     GEQIPQNEQNSLRGAENDLKRYTQKMTLEVYFVDTAEKDRFKAGLSQLGFDFKKNYQV
                     SGYQRIEPLTQAELNEQWGGNHGHQKNI"
     gene            26833..27156
                     /locus_tag="VXE87_000984"
     CDS             26833..27156
                     /locus_tag="VXE87_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842545.1"
                     /translation="MDIRKISDSVAIYSDGKKLHVIHNLGDEFILDFKVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEIFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            27149..27484
                     /locus_tag="VXE87_000985"
     CDS             27149..27484
                     /locus_tag="VXE87_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEV0842546.1"
                     /translation="MIKTVFFSCDYPHHEAIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            27579..27995
                     /gene="ssb"
                     /locus_tag="VXE87_000986"
     CDS             27579..27995
                     /gene="ssb"
                     /locus_tag="VXE87_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0842547.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFKAWRGTADIIAQYCSKGSLIGIIGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            28008..28703
                     /locus_tag="VXE87_000987"
     CDS             28008..28703
                     /locus_tag="VXE87_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0842548.1"
                     /translation="MEIDKIIKKDVLEFMETIPDNKIDLIVTDPPYLINYKTNWRKEK
                     HKFSNVIKNDNNPELIKEYIKECYRILKDDTAIYIFCSFDKVDFFKKEIEKYFSVKNI
                     IIWRKNNHTAGDLEAQFGKQYEMIILANKGRKKFNGERLTDVWDFKRVSSDKLLHQNQ
                     KPIELIKRCIVKHSDVGDTVFDGFMGSGTTALAALETDRHFIGTEIDEYYFGIAEERI
                     KNHNAQLSLFDEV"
     gene            28705..28914
                     /locus_tag="VXE87_000988"
     CDS             28705..28914
                     /locus_tag="VXE87_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842549.1"
                     /translation="MEWTDWVDWKPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     LDIKRDCLRLGVPFEDVYPLQTTLF"
     gene            28928..29257
                     /locus_tag="VXE87_000989"
     CDS             28928..29257
                     /locus_tag="VXE87_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842550.1"
                     /translation="MASKINATERIAIIIDKQKIEVVTTLNYDMSISFDNKDTAPTLD
                     DNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNIKTLQEVKKFFEFVNENRENLFEMA
                     GFKGALE"
     gene            29254..29685
                     /locus_tag="VXE87_000990"
     CDS             29254..29685
                     /locus_tag="VXE87_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEV0842551.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRARLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEIEVMKSLSI"
     gene            29701..29883
                     /locus_tag="VXE87_000991"
     CDS             29701..29883
                     /locus_tag="VXE87_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842552.1"
                     /translation="MADYALYQGDVFVTLGTLAQISSETGITERMLKYYTYTSHQRRH
                     PNGRAVIKIEEEDNEN"
     gene            29908..30225
                     /locus_tag="VXE87_000992"
     CDS             29908..30225
                     /locus_tag="VXE87_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842553.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWIGYSPSMAQVVIAVYLIY
                     GGN"
     gene            30227..30715
                     /locus_tag="VXE87_000993"
     CDS             30227..30715
                     /locus_tag="VXE87_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0842554.1"
                     /translation="MNKQELIEKYKKLEGVWNAEGAELARQIFLQDLEQLDKPKPVKV
                     PQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPEWFYENNIEKFCLAWLDGYEVEKE
                     KRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDANFGWVFDCPGIEIEE
                     VE"
     gene            30715..30876
                     /locus_tag="VXE87_000994"
     CDS             30715..30876
                     /locus_tag="VXE87_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842555.1"
                     /translation="MSLTLNSTIGDLVLAIGEIIVGSDGKTTTAILEIPDQSFYLEIE
                     LKLKEEVIN"
     gene            30873..31133
                     /locus_tag="VXE87_000995"
     CDS             30873..31133
                     /locus_tag="VXE87_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEV0842556.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYDKVKVGDEVLL"
     gene            31130..31552
                     /locus_tag="VXE87_000996"
     CDS             31130..31552
                     /locus_tag="VXE87_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842557.1"
                     /translation="MTETIKLPDYYEPDWKNARYGSLEELKELLLFKRIVKWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQDVSLDAVITNIEIGEPEEIPDHWGTGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVCSLVIGDIHFPVVNA"
     gene            31564..32001
                     /locus_tag="VXE87_000997"
     CDS             31564..32001
                     /locus_tag="VXE87_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842558.1"
                     /translation="MTPRYRAWIKTEKRMFFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            31998..32369
                     /locus_tag="VXE87_000998"
     CDS             31998..32369
                     /locus_tag="VXE87_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842559.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            32442..32846
                     /locus_tag="VXE87_000999"
     CDS             32442..32846
                     /locus_tag="VXE87_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0842560.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            32927..33009
                     /locus_tag="VXE87_001000"
     tRNA            32927..33009
                     /locus_tag="VXE87_001000"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32958..32960,aa:Tyr,seq:gta)
     gene            33314..33754
                     /locus_tag="VXE87_001001"
     CDS             33314..33754
                     /locus_tag="VXE87_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0842561.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            33732..>34654
                     /locus_tag="VXE87_001002"
     CDS             33732..>34654
                     /locus_tag="VXE87_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0842562.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWGNLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITVKATGQKILFRGLDDELKITSITVDIGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLIT"
BASE COUNT        10722 a         6139 c         7856 g         9937 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttggggtata gccaagcggt aaggcaaggg actttgactc
      301 cctcatgcgt tggttcgaat ccagctaccc cagttactat ttgccggcgt ggcggaattg
      361 gcagacgcgc tggactcaaa atccagtgtc cgcaaggacg tgccggttcg accccggccg
      421 ccggtatagt atagtgttag gaacgttgtt attcttcgtt ccttttttat attatttttg
      481 gtataattat agttattcaa attttattta gattaagaaa gtgtagggta gtatgtcttg
      541 ttctatcgat ttattaaaac atcggtattt gaaaaatatt aaagaaaatc ctgaattgtt
      601 tgtcggaatt gagttggagt atcctgttgc aagtttagaa ggggatgcta cagatgttga
      661 agttataaag gatctatttc attatttagt ttctactttg gatctcaccg tagcaaaggt
      721 agatgatttt ggcaatttga tccagttagt agatccgata agtcaggatg ctattttatt
      781 tgaagtttcc tatacaacga ttgagtttgc atttggtaag gctgaaacga tacaagaagt
      841 tgaagaacgt tttagtattt atatggaagc aatccagaag aagttagctg aatcaaatca
      901 tgctattgtt ggctgtggta tccatcccaa ctgggataaa aatgagaatt gtccagtggc
      961 ttatccacgc tatcagatgt tgatggatta tttgaatttg agtagaaata ttattaaatc
     1021 agatttacat catttccctg aatatggtac ttttatctgt gggagccagg ttcagctgga
     1081 tatttcaaaa accaactact tacgggtgat taatgctttt actcaaattg aagcggctaa
     1141 ggcttattta tttgcaaact ctgagttttc gggtgcggat tgggatacga aaatttcaag
     1201 ggatattttc tgggaagaat ctatgcatgg tatctatcca gagaatgttg gggtcaatgc
     1261 tagactcctt aatgatgaag ctgatttttt tgactatcta aatcattctg cgatttttac
     1321 tgcggaacgt gatgggcaga cctattattt ttatcctatt caggctgggg actatttggc
     1381 tacgcctgaa atccaagcat ttgctctgaa tggggatgag gttattattt ccccccaaga
     1441 gaaggatttt gaaactcatc gtagttacca gtaccaagac ttaacgactc gaggaacagt
     1501 tgagtttcgt agtgtgtgta cacagccact tgataggact tttgcttctg cagcttttca
     1561 cttgggatta ttggttaatt tagacaagtt agaagcttac ttagaaacag cacctttctt
     1621 taaagtattt ggttatgatt acaagtcttt aaggagacaa ttttctaaga aaaatcttac
     1681 agatgaggaa gaaactacga ttattgaatt ttccaaagac ttactcctac tagctgagga
     1741 gggactagtg gtgagaaata aggaagaaat gacctattta cagcctttga gagaagaatt
     1801 gagcctataa tttctcttat aaagggagaa ttttctgaaa aatcatgata taatggacga
     1861 gactatagat aaaggataga gagtaatgac attagtttat caatcaacgc gtgatgccaa
     1921 caatacagta actgccagcc aagcaatttt gcaaggtttg gcgacggacg gcggtttgtt
     1981 tacaccggtt acttatccaa aggtagattt gaactttgac aaattgaaag atgcttctta
     2041 ccaggaagtt gctaagctag ttttgtcagc atttttagat gactttacag ctgaggagtt
     2101 ggactactgt atcaacaatg cctacgatag caaatttgat actccagcta ttgcaccatt
     2161 agtgaaatta gatgggcaat acaatttgga acttttccat ggttcaacga ttgcctttaa
     2221 ggatatggcc ttgtctattt tgccatactt tatgacgact gctgctaaga aacatggttt
     2281 ggagaacaag attgttatct tgacagcgac atctggtgac acggggaaag ctgctatggc
     2341 ggggtttgcg gatgtgcctg gtactgagat tatcgtcttt tatccaaagg gtggtgtcag
     2401 caaggtacaa gagttgcaaa tgaccactca gaatggtgac aatactcatg ttatcgctat
     2461 agatggtaac tttgacgatg cacaaaccaa cgtgaagcac atgtttaacg acgtggctct
     2521 tcgtgaaaga ttagcggcca acaagttgca attttcatct gctaactcta tgaatatcgg
     2581 tcgtttggtg ccacagattg tttattatgt ttatgcctat gctcagttgg tcaagactgg
     2641 tgagatcgtg gctggtgata agattaactt cacagtacca acaggaaact ttggaaatat
     2701 cttggctgcc ttttatgcca aacaaatcgg tctcccagtt ggtaaattaa tctgtgcttc
     2761 aaatgacaac aatgttttga cagacttctt taaaacacgt gtctatgaca aaaaacgtga
     2821 gtttaaggta acaaccagcc catctatgga tatcttggta tcttcaaact tggagcgctt
     2881 gattttccat cttttgggaa ataatgctga aaagacaact gaacttatga atgccttgaa
     2941 cacgcaagga caatataagt tgacagactt tgatgcagag attttggacc tctttgcagc
     3001 tgaatatgcg actgaggaag aaacggcagc agagatcaag cgtgtttgtg agttagattc
     3061 ttatatcgag gaccctcata cagctgttgc ttcagcagtt tataaaaaat accaatcggc
     3121 cactggagat gtaactaaga cagtgattgc ttcaacagct agtccataca agttcccagt
     3181 agttgcagta gaagctgtaa ctggaaaagc aggtttaaca gactttgaag ccttggctca
     3241 attacatgaa atctcaggcg ttgcagtgcc accagcagtt gatgggcttg aaatagctcc
     3301 aattcgtcac aagacaacag tggcagctgc tgacatgcaa gcagcggttg aggcttattt
     3361 aggactttaa gacagaggga gcaaactcgg ttgggaaacc aactgagttt cttttcatca
     3421 ggaggagaga ttgtttaaga aaaataaaga cattcttaat attgcattgc cagctatggg
     3481 tgaaaacttt ttgcagatgc taatgggaat ggtggacagt tatttggttg ctcatttagg
     3541 attgatagct atttcagggg tttcagtagc tggtaatatt atcaccattt atcaggcgat
     3601 tttcatcgct ctgggagctg ctatttccag tgttatttca aaaagcatag ggcagaaaga
     3661 ccagtcgaag ttggcctatc atgtgactga ggcgttgaag attaccttac tattaagttt
     3721 ccttttagga tttttgtcca tcttcgctgg gaaagagatg ataggacttt tggggacgga
     3781 gagggatgta gctgagagtg gtggactgta tctatctttg gtaggcggat cgattgttct
     3841 cttaggttta atgactagtc taggagcctt gattcgtgca acgcataatc cacgtctgcc
     3901 tctctatgtt agttttttat ccaatgcctt gaatattctt ttttcaagtc tagctatttt
     3961 tgttctggat atggggatag ctggtgttgc ttgggggaca attgtgtctc gtttggttgg
     4021 tcttgtgatt ttgtggtcac aattaaaact gccttatggg aagccaactt ttggtttaga
     4081 taaggaactg ttgaccttgg ctttaccagc agctggagag cgacttatga tgagggctgg
     4141 agatgtagtg atcattgcct tggtcgtttc ttttgggacg gaggcagttg ctgggaatgc
     4201 aatcggagaa gtcttgaccc agtttaacta tatgcctgcc tttggcgtcg ctacggcaac
     4261 ggtcatgctg ttggcccgag cagttggaga ggatgattgg aaaagagttg ctagtttgag
     4321 taaacaaacc ttttggcttt ctctgttcct catgttgccc ctgtccttta gtatatatgt
     4381 cttgggtgta ccattaactc atctctatac gactgattct ctagcggtgg aggctagtgt
     4441 tctagtgaca ctgttttcac tacttgggac ccctatgacg acaggaacag tcatctatac
     4501 ggcagtctgg cagggattag gaaatgcacg cctccctttt tatgcgacaa gtataggaat
     4561 gtggtgtatc cgcattggga caggatatct gatggggatt gtgcttggtt ggggcttgcc
     4621 tggtatttgg gcagggtctc tcttggataa tggttttcgc tggttatttc tacgctatcg
     4681 ttaccagcgc tatatgagct tgaaaggata ggaaatgcaa aaaacagctt ttatttggga
     4741 tttagacggg actttattgg actcttacga agcgatttta tcagggattg aggagacttt
     4801 tgctcagttt tctattcctt atgataagga gaaggtgaga gagtttatct tcaagtattc
     4861 ggtgcaagat ttgcttgtgc gggtggcaga agatagaaat ctggatgttg aggtgctaaa
     4921 tcaggtgcgt gcccagagtc tggctgagaa gaatgctcag gtagttttga tgccaggtgc
     4981 gcgtgaggtg ctagcttggg cagacgaatc aggaattcag cagtttatat atactcataa
     5041 ggggaacaac gcttttacca ttctcaagga cttgggggtg gaatcctatt ttacagagat
     5101 tttaaccagt cagagtggct ttgtgcggaa gccaagtcca gaagcggcta cctatctgct
     5161 agataagtat cagttgaatt ctgataatac ttattatata ggggatcgga ctctggatgt
     5221 ggaatttgcc cagaatagtg ggattcaaag tatcaacttt ttagagtcta cttatgaagg
     5281 gaatcacagg attcaagcgt tagcagatat ttcccgtatt tttgagacta agtgataaaa
     5341 agattgtgtc agttttgtga cagagaccta acaaactatt tcaagtaacc tagtttgtta
     5401 caaggaatag acagttctgt taaataggcc cgagagggct ttttttctac attttttgtg
     5461 ttatgataga caggtactca tttgaaagga atttgaaaga atgaagaaaa gaatgttatt
     5521 agcgtcaaca gtagccttgt catttgcccc agtattggca actcaagcag aagaagttct
     5581 ttggactgca cgtagtgttg agcaaatcca aaacgatttg actaaaacgg acaacaaaac
     5641 aagttatacc gtacagtatg gtgatacttt gagcaccatt gcagaagcct tgggtgtaga
     5701 tgtcacagtg cttgcgaatc tgaacaaaat cactaatatg gacttgattt tcccagaaac
     5761 tgttttgaca acgactgtca atgaagcaga agaagtaaca gaagttgaaa tccaaacacc
     5821 tcaagcagac tctagtgaag aagtgacaac tgcgacagca gatttgacca ctaatcaagt
     5881 gaccgttgat gttcaaactg ttcaggttgc agacctttct caaccgattg cagaagctcc
     5941 aaaagaagta gcatcaagtt cagaagttac aaagacagtg attgcttctg aagaagtggc
     6001 accatctacg ggcacttctg tcccagagga gcaaacggcc gaaacaactc gcccagttga
     6061 agaagcaact cctcaggaaa cgactccagc taagaagcag gaaacacaag caagccctca
     6121 agctgcatca gcagtggaag caactacaac aagttcagaa gcaaaagaag tagcatcatc
     6181 aaatggagct acagcagcag tttctactta tcaaccagaa gaaacgaaag taatttcaac
     6241 aacttacgag gcaccagctg cgcccgatta tgctggactt gcagtagcaa aatctgaaaa
     6301 tgcaggtctt caaccacaaa cagctgcctt taaagaagaa attgctaact tgtttggcat
     6361 tacatccttt agtggttatc gtccaggaga cagtggagat cacggaaaag gtttggctat
     6421 cgactttatg gtagcagaac gttcagaatt aggggataag attgcggaat atgctattca
     6481 aaacatggcc agccgtggca ttagttacat catctggaaa caacgtttct atgctccatt
     6541 cgatagcaaa tatgggccag ctaacacttg gaacccaatg ccagaccgtg gtagtgtgac
     6601 agaaaatcac tatgatcacg ttcacgtttc aatgaatgga taaacccgac ttgataacat
     6661 cattttgacg aatgagatct agctttcgtg atggaaagcg attctcgttc gttttttctt
     6721 tgtcatactc ttcgaaaatc tcttcaaacc acgtcagttt tatatgaaac ctcaaagctg
     6781 tgctttgagc aacctgcgac tagcttccta gtttgctctt tgattttcat tgagtatcaa
     6841 tttgaatgga aaatgggaag ttaccatatt gtaatgagtt aagtaacatt cttgcaatct
     6901 attttacttt gcattatacg tgattagtca aatattgata aatcaataaa aagagagggg
     6961 aagaaatgct agagattcaa gatttactgt atcaactccg cttgtctgag caagcgagta
     7021 cgcaattgtt tgaaaaaagg cttggattag tttgacacgg tatcagattt tactgttttt
     7081 gctggagcat tctccttgta accaaatggc ggttcaggag cgtttgaaaa ttgatcaggc
     7141 tgctttgaca cggcatttca agattttgga aacggaaggt ttggtggagc gtcatcgtaa
     7201 tcctgaaaat cagcgggaag tgttggtaga gactgcgaag tatgccaagg agcagttagt
     7261 ggtgaatccc cctctgcaac atatcaaggt taaggaagag atggaaagta tcttaacaga
     7321 gtttgagaga acagaactca gccgtttatt aaataaattg gttttgggta ttgaaaatat
     7381 agaaatttaa ggagaaatag atgtcaatta ttacaattat tttaacaacg atcgttgctt
     7441 tggagcattt ttacattttt tatttggaaa gtattgccac gcaatcagat gcgactagtc
     7501 gtgtatttaa tatggaaaag gaagaattgg ctcatccgtc agtaagttca ttgttcaaaa
     7561 atcaagggat ttataaggct ctgctaggag tctttctctt gtatgtcatt tatttctcac
     7621 agaatttaga aattgtgact atttttgtct tatttgtgat tggtgctgcg acttacggct
     7681 ctttaacagc ggataaaaaa attattttga aacaaggtgg atcagctatt ttggccttga
     7741 ttagtatttt actctttaaa tacacttgaa ggtcgattct aatctcgcta atccttttta
     7801 atccagaata agggaaatat gttatacttg tttttaagaa aaaagtttca ttgaattggt
     7861 tttgaggagt tagaaatgaa agtattagtg acaggttttg agcccttttg aggccattaa
     7921 aggtttacca gctgaaatcc atggtgctga ggtccgttgg ctagaggtgc cgacagtttt
     7981 tcacaaatct gctcaagtat tggaagaaga gatgaatcgt tatcaacctg actttgtcct
     8041 ttgtattggg caagctggtg gaagaactag tttgacacct gaacgagtgg ccattaatca
     8101 agacgatgca cgcatttctg ataacgaaga taatcaaccg attgaccgtc ccattcgccc
     8161 agatggtgct tcggcctact ttagtagttt gccgattaaa gcgatggttc aagctataaa
     8221 aaataaggat taccggcctc tgtttccaat acggcaggga cttttgtctg cagccatttg
     8281 atgtatcagg ctctctattt ggtagaaaag aaatttccat atgttaaggc aggttttatg
     8341 catattcctt atatgatgga acaggtggtg aacagaccga ctactccaac tatgagttta
     8401 gtggatattc ggcgagggat agaagcagca atcggcgcta tgatagaaca tggagatcag
     8461 gaactcaagt tggtaggcgg agaaattcat tgatagaaaa aagcttgagg ggaaaacctt
     8521 caagcttttg gacgttttcg agccaatact gctcggtaaa acataatttt agtgcattgg
     8581 atataaggta ggagtgaaaa actagcaatg ccaaaggtaa tccaattgag gaagtaccaa
     8641 ggaagaagct gtaaatctag gacaaagtgc tggaacttgt agcccttcat aaaggaacgg
     8701 ctagttttta ggattcgtct tggtgggacc tgtcctaggt ctaaactata acagagaaga
     8761 aattccacct gtgaataggc ataatactgt ggaatataga ggatatttcc tacaatgatc
     8821 aagatgagac ttgcaagaaa gtagagtcca aagaccatga ggaaacgctc ggtttcaact
     8881 gatgagagat ctagatttgg aaactcagga tgtagggtga cgaatttttt ggctaaaaag
     8941 ctactataaa agaggaggta aatcccaagt aaattaggga tactccataa aaagagatag
     9001 aaacgtttga gaagtagggt caaaaaggtt tgagaaaagc gctcctcatc aaagagagct
     9061 aggctgtttt ttacagatgg ctccgtttta gaatctttca tgagtgtcag tgttgcatag
     9121 acggaactgg tcaaaagaat agtcccgata aaggagacta gtagaggaaa gaggtaggtt
     9181 tgaagtattt ggccaagtat gctgaaaaat ggctgttcta aaacagtccc gtggatccga
     9241 gataagggat taagaaaacc agataagatg accagcatac tgggaaggat atagaggaga
     9301 aagagacggg gggtgtcagc ctgaaaatgt tttgactcct gacgaattgt ttttaaatca
     9361 atttttggat agttcattct cttattatac catagttctt atacatagtt cgtgacagtt
     9421 cctacttttt ttgataaaat catacagtgt gtccttgggc acactgtatg aactgggact
     9481 gtctttccca gcttcggagg taaaaaatgt cagattcacc aatcaaatat cgtttgatta
     9541 agaaagaaaa acacacagga gctcgtctag gagaaatcat cactccccac ggtacctttc
     9601 cgacacctat gtttatgcca gttgggacac aagccactgt caaaactcag tcacctgaag
     9661 aattgaagga gatgggttcg ggaattatcc tatcaaacac ctatcatctc tggcttcgcc
     9721 ctggagatga actcattgca cgcgctggtg gtctccacaa gttcatgaat tgggaccagc
     9781 ctatcttgac agatagtggt ggttttcagg tttattcttt agcagatagc cgtaatatca
     9841 cagaagaagg agtaaccttt aaaaatcatc taaatggttc taagatgctc ctatccccag
     9901 aaaaagccat ctctattcag aataatctga gttcagacat catgatgtcc tttgatgaat
     9961 gtcctcagtt ttatcaacct tatgactacg ttaagaaatc gatcgagcgt accagccgtt
    10021 gggctgagcg tggtttgaag gctcaccgtc gtccacatga ccaaggtttg tttggaattg
    10081 tgcaaggtgc aggatttgaa gaccttcgcc gccaatcagc tcacgatctt gtcagcatgg
    10141 atttctcagg ctactctatc ggtggtttgg cagtgggaga aacccatgaa gagatgaatg
    10201 cggtcttgga ctttacaact caactgctgc ctgaaaataa acctcgttat ctgatgggtg
    10261 tgggagcgcc agatagcttg atcgatgggg tcattcgtgg ggtggatatg tttgactgtg
    10321 tcttaccgac tcgaattgct cgtaacggga cttgtatgac cagtcaagga cgtttggttg
    10381 tgaaaaatgc ccagtttgct gaggacttta cgccactgga tcctgagtgt gattgctaca
    10441 catgtaataa ctatacacgc gcttaccttc gtcacctgct caaggctgat gaaacctttg
    10501 gtatccgctt gactagctac cacaatcttt acttcttgct taacctgatg aagcaagtgc
    10561 gacaagccat catggatgac aatctcttgg aattccgtaa gtattttgtg gaaaaatatg
    10621 gctataataa gtcaggacgt aatttctaaa atggaattga tataagctaa aaatcctaag
    10681 ttttctctta ggatttttct tctttttttg atagaataaa gtgtacaatg aaaggaagaa
    10741 taaactcgta tgcgcattaa atggttttcc ttgattagga ttataggttt acttttggta
    10801 ctcttgtatc acttctttca gacgatcttt cctggaggat ttttcggggt agatgtcttt
    10861 ttcacatttt caggtttcct gattacagct ctactcattg aagaattttc taagaacaat
    10921 gagattgatt tgataggatt ttttagaaga cgcttttatc ggattgtgcc acctgtggtt
    10981 ttgatggtct tggtgaccat gccttttact ttcttggttc gccaagacta tgttgctgga
    11041 attggtggcc agattgcggg cgtcttaggc tttatgacca acttctatga actcttaaca
    11101 ggtgggagtt atgaatctca gttcattcct catttgtttg ttcataattg gagtttggca
    11161 gttgaggttc actactatat tctttgggga ttggcagttt ggttcttatc caaacaagct
    11221 aaatcaaatg gtcagttgaa ggggatgatc tttctcttat ctgctactgc cttcttgatc
    11281 agtttcttct ccatgtttat tggtagtttt ctagtgacct cttattcctc tgtttatttc
    11341 tccagtttaa ctcatgtcta tccattcttt ttgggaagta tgttagcaac tattgtaggc
    11401 gttcgtcaga cgacttccct cgtcaagcag ttggataaaa tctgggattt acgaaagact
    11461 ttggtagttt ttggaggagg ctttggtttc ctagttcttt tgactttctt tgtcaaattc
    11521 acttatcttt ttgcctatct tatcggcttc ttgcttgcca gtcttgcagc tcttgccatg
    11581 attctggcgg cgcgtgtctt acatgaaaag acacatcata tacaggagcc gaagattatc
    11641 agctttttag cggatactag ctatgcggtt tatcttttcc attggccttt ctatatcatt
    11701 ttctcacagt tgacatcaaa tcttcttgct gtattactga ctctgatttg ttcttatggc
    11761 tttgccagtc tgtcatttta tgtattggaa ccttggattg caggcaagaa cacacctatt
    11821 gtccaaaccc ttcgtcccct gccttatatt cacgcaattc ttgcagcagg tacaggaatc
    11881 ttgaccttca ttgtctgcat ggtgaccttg ttggcaccac aagtgggagc gtttgagaca
    11941 gacttgactg tcaatggctt gaagcaagct gcaacaaata ttggccagac caaggtgatg
    12001 gcagaacggg cagatgcaaa cagtttggga attgctgatg gcactatgtt aattggtgac
    12061 tcagtggctt taagggcaaa tacagcacta cagacagctc ttcctggagc acagattaac
    12121 gcgcaggtca gcgtaacaac caagaccgca aatgaaatca tgctaaataa tagccagaat
    12181 aaatttttac ctaagacggt ggtcattgcg actggggtaa ataatcctga gaactacaag
    12241 gatgactggg acagtatcgt gaaaaatctt cctaagggac accatatgat tttggtgact
    12301 ccttatgagg gagataagac aaaagagacc tatgccatcg ttgagaaggc tgctgcctat
    12361 atgagagaat tggcagagaa gacaccttac attacgatag cagattggaa tcaagttgcg
    12421 aaagagcatc cagaaatttg ggctggaaca gatcaggttc atttcgggag tgagagtagc
    12481 actatcgaag caggagcaaa attgtatgca gatacgattg ccacagcttt gcagacagct
    12541 caagacaagc cggttaaatc aaaataactt gtattaaaaa agagaagagt tggagaaatc
    12601 cagctctttt aaaatatctc caaaaaatag gtatatacca tttacaaata aaaaagaaag
    12661 gtttataatg taattgatat aacaaattgt agaatcaatc ttttaaggag gttaacatta
    12721 tgcctaacta tattaaagcg gatcagtttt tctacccaca cggagttcgt cgaggtggtt
    12781 acttggaact tgtggacggc aagtttggaa aacatgtaga gcagattcct gaaggggctg
    12841 aggtgattga ctatacaggt tatagcattg ccccaggtct tgtggatact catattcatg
    12901 gatatgcagg tgtagatgtg atggacaaca acattgaagg tacattgcat actatgagtg
    12961 aaggacttct tagtaccggt gttaccagtt tcttacccac aactttaaca gccacttatg
    13021 agcaattgct tgcagtcact gaaaatcttg gaaaccatta taaagaagca acaggtgcta
    13081 agattcgtgg gatttattat gaaggtccat atttcacaga aacttttaag ggggcacaaa
    13141 atccaactta tatgagagac ccgggtgttg aggagtttca ttcttggcaa aaagcggcaa
    13201 atggcttgct taataaaatt gcccttgcac cagaacgtga tggggtggaa gactttgttc
    13261 gtacagttac gggcgaaggt gtgacggttg ctcttggaca ttcaaacgcg acttttgatg
    13321 aagccaaaaa agcagtcgat gctggagcga gtgtttgggt gcatgcctac aatggaatgc
    13381 gtgggttgac tcaccgtgaa ttgggtatgg ttggagccat gtaccaattg ccacatacct
    13441 atgcagagtt gatctgtgat ggtcaccacg tagatccaaa ggcttgcgaa attcttatca
    13501 aacaaaaagg aacagaaaac atcgctctta tcacagactg tatgacagct gggggattgg
    13561 aagacggaga ttatatgttg ggagaattcc cagttgtcgt tgcaaatgga actgcacgcc
    13621 tcaaatcgac aggtaacttg gcaggttcta tcctcaaact caaagatggt ttgaagaatg
    13681 tggtcgaatg gggaattgcg aatccgcatg aagcagtcat gatggccagc ttcaacccag
    13741 ctaaatccgt tcacatcgat gacgtctgtg gccaaatccg tgaaggctac gacgctgact
    13801 tcatcgtatt agataaagat ttggaattgg tagcaaccta cctagatggc gtgaaacgtt
    13861 atcaagcata agagagaaag cagaagttag agactaactt ctgctttttt atgcagggta
    13921 ctttactggt aaataaaaag ttaaaaaaat cacaaaaaaa gcttgaagaa acaaagaaaa
    13981 aggcttacaa ttgaactata aatagtacaa ataaaaaaac ggaggagtgc tttatgaaag
    14041 cttatactta tgttaaacca ggacttgctt cttttgttga tgtagacaaa ccagttattc
    14101 gcaagccaac agacgctatt gtgcgtattg taaaaaccac tatttgtgga acagacctcc
    14161 atattatcaa aggggatgtt cctacttgcc aaagtggtac cattcttggc cacgaaggga
    14221 ttgggattgt tgaagaagtt ggggaaggag tttccaactt caaaaaaggt gacaaggtct
    14281 tgatttcttg cgtctgtgcc tgtggtaaat gctactactg taaaaaagga atttatgccc
    14341 actgtgaaga cgaagggggc tggattttcg gtcacttgat tgatggtatg caggctgaat
    14401 atctacgtgt ccctcatgca gataatactc tttaccatac tccagaagac ttgtcagatg
    14461 aagctttggt tatgctgtca gacattctgc ctactggata tgaaattggt gtcttaaaag
    14521 ggaaagtaga acctggttgc agcgtagcca ttattggttc aggtccagtt ggattggctg
    14581 ctcttttaac agcccaattc tattcaccag ctaaattgat tatggtagac ctagacgata
    14641 accgcttgga aactgcccta tcattcggtg cgactcataa ggttaattct tcagaccctg
    14701 aaaaagccat taaagaaatt tatgatttga cagatggtcg tggtgtggat gtcgctatcg
    14761 aagctgttgg tattcctgca acatttgatt tctgtcaaaa gattatcggt gtagacggaa
    14821 cggttgccaa ctgtggtgtg catggtaaac cagttgaatt cgatttagat aaactttgga
    14881 ttcgcaacat caatgtaaca actggtttgg tatctacaaa tacgactcca caattgttga
    14941 aagcacttga aagtcataag attgaaccag aaaaattggt aactcactat ttcaaactca
    15001 gtgaaattga aaaagcctac gaagtcttca gtaaggcagc agaccaccat gccattaagg
    15061 tcattatcga aaacgatatc tcagaagcct aagtagtaaa aatatttttg tacataagta
    15121 aatagaaatt cagtcatcca tcagatggct ggatttttta tcaaaaaatt cagaaatgag
    15181 catatttctt tccttgtctg gcggaattgg ttataatata cggtacaaag gaatgaatga
    15241 atatgtatcg tgttatagaa atgtacggag attttgaacc gtggtggttc ttagaaggtt
    15301 gggaagaaga tattgtagca agtagaaaat ttgatcagta ttatgatgct ctcaaatact
    15361 acaaaacttg ctggtttaga ttggaacaag aatcccctct ttataaaagt agaagcgatt
    15421 tgatgaccat tttttgggac ccggaagacc aacgctggtg tgatgaatgt gatgagtatt
    15481 tacaacaata ccattctttg gctcttttgc aggatgagca ggttatccca gacgaaaaac
    15541 tacgctcagg ctatgaaaaa caaaccagtc aggaaaggaa tcgttcttgc cgtatgaaat
    15601 taaaatagag aaaagtaact tttttggagt tgcttttttt atttttctaa ctctttgcga
    15661 atagtatagg tgaggaggta agtatggttc aagaaattgc acaagaaatc attcgttcag
    15721 ctcgggaaaa agggacgcag gatatttatt ttgtccctaa gttagacgcc tatgagcttc
    15781 atatgagggt aggagacgag cgctgtaaaa ttggtagcta tgattttgaa aagtttgcag
    15841 ccgttatcag tcactttaag tttgtggcgg gtatgaatgt gggagaaaaa agacgtagtc
    15901 aactgggttc ctgtgattat gcctatgacc agaagatggc gtctctacgt ttatctactg
    15961 taggcgatta tcgggggcat gagagtttgg ttatccgttt gttgcacgat gaggaacagg
    16021 acttgcattt ttggtttcag gatattgaag aattaggcaa gcagtacagg caacggggac
    16081 tctatctttt tgctggtccg gttgggagtg gtaagacgac cttgatgcat gaattgtcca
    16141 agtcactctt taaaggacag caagttatgt ccatcgaaga tcctgtcgaa atcaagcagg
    16201 acgacatgct tcagttgcag ttgaacgaag caatcggcct aacctatgga aatctaatca
    16261 aactttcctt gcgtcatcga ccagatctct tgattatcgg agaaattcgt gacagcgaga
    16321 cggcgcgtgc agtggtcaga gctagtttga caggtgcgac agtcttttca accattcacg
    16381 ccaagagtat ccgaggtgtt tatgagcgtc tgctggagtt gggtgtgagt gaagaagaat
    16441 tggcagttgt tctgcaagga gtctgctacc agagattaat cgggggagga ggaatcgttg
    16501 actttgcaag cagagattat caagaacacc aagcagccaa gtggaatgag caaattgacc
    16561 agcttcttaa agatggacat atcacaagtc ttcaggctga gacggaaaaa attagctaca
    16621 gctaagcaaa aaaatatcat caccctattt aacaatctct tttctagcgg ttttcatctg
    16681 gtggagacta tctccttttt agataggagt gctttgttgg acaagcagtg tgtgacccag
    16741 atgcgtgtgg gcttgtctca ggggaaatca ttctcagaaa tgatgaaaag tttgggatgt
    16801 tcaagtgcta ttgtcactca gttatcccta gctgaagtcc atggtaatct ccacctgagt
    16861 ttgggaaaga tagaagagta tctagacaat ctggccaagg tcaagaaaaa attaattgaa
    16921 gtagcgacct atcctttgat tttgctgttt tttcttctct taattatgct ggggctacgg
    16981 aattacctgc tcccacaact ggatagtagc aatattgcca cccgaattat cggtaatctg
    17041 ccacaaattt ttctaggcat ggtagggctt gtttccgtgc ttgccctttt agcactaact
    17101 ttttataaaa gaagttctaa gatgagtgtc ttttctatct tagcacgcct tccctttatt
    17161 ggaatctttg tgcagaccta cttgacagcc tattatgcac gtgaatgggg gaatatgatt
    17221 tcacagggaa tggagctgac gcagattttt caaatgatgc aggaacaagg ttcccagctc
    17281 tttaaagaaa tcggtcaaga tctggctcaa accctgaaaa atggccgtga attttctcag
    17341 acgataggaa cctatccttt ctttaggaag gaattgagtc tcatcataga gtatggggaa
    17401 gttaagtcca agctgggtag tgagttggaa atctatgctg aaaaaacttg ggaagccttt
    17461 tttacccgag tcaaccgcac catgaatttg gtgcagccac tggtttttat ttttgtggca
    17521 ctgattatcg ttttacttta tgcggcaatg ctcatgccca tgtatcaaaa tatggaggta
    17581 aatttttaaa atgaaaaaaa tgatgacatt cttgaaaaaa gctaaggtta aagcttttac
    17641 attggtggaa atgtaggtta ctaaaattat ttatattttc caattgataa caatgtcctc
    17701 agctgtcacc ttaaccttgt ttataagcct tctaacaagc accttttgat tttcgtagtc
    17761 cattgaaaag actttctcag cgtttagcag tttcctcata tcagcctttc ttttgttctt
    17821 cctgagtgct ggatcgtttt ctagttcagt ttcaagagtc cccctcatgc ttataaattc
    17881 ggctgacttg ctctgtaatt cttcaagggt aatgcggtca tctatgtata gatcgttaag
    17941 tctgctcagt ttctttgata gctcctctat ttgtttctta tagctctcac ggtctatggt
    18001 ctcagcattg tctcctgaaa atattttgtc caggtaatca gcgtcatctt gtagtttgct
    18061 tatttctttt agcacagagg cctctagctt gtctttgtag taaaatcctg agtcacactt
    18121 tttattgtcg ttgtaggtag taacgcctct cagcgttcgt gggtgccttt ggtggcattc
    18181 atattttttt aacctgctcc catctttcct ctttacgcct aacataattt ttaaaggagc
    18241 gccacaatat ccacattggg cgataccgga taaaatgtac ttagcttgga atggtctagg
    18301 attgacattc tctgctgctg ttctttgtct tatttttagc tcagattgag tcttatcgta
    18361 ttcctctttt gaaataatcg gctcatgatt acctggataa atttctccct tatactgatt
    18421 gaaaccacaa tagacagggt tatcgagtat ggttctgacc gcccgatagc tccaaggcac
    18481 atgctttggg tatttctcat ttagatcatc tctcaactta gtaatagatc tccctctcag
    18541 gtaactctca aagataaact taatggtcag agcctgagct ggattgatgg tcactgtgcc
    18601 tgtctctttg tggtaatcgt aaccatagga tgtcttagcc cacatcatgg atttaccaga
    18661 tttggcacgt cctagcttgc caagttgcat gcgttccttg atttgctccc tttctagctg
    18721 agcaaagacg ctcaagagtc caatcatagc cttaccaaaa ggagtagagg tgtcaaagtt
    18781 ctcctgcaag ctcagaaatt caatcccatt cttgatgaat acatcctcaa tcaagtgaag
    18841 cgtgtctttt tgactacggc taagacggtc cagcttatag actagaacag tgtcaaattt
    18901 tcttttttta gcgtctttga taagactttc tagcgctggt ctgtcagtat tggatcctga
    18961 gaaacctcca tcagtatata ctttgtatac attccagtct ttaatgtcgc agtagctaga
    19021 gagcttgtct ttttgctcat ctatagagta tccctcctca acctggtttg tcgtcgatac
    19081 cctgacatat atagctactt tatttgttgt tatcatagta gtacctcttt caaaatttcc
    19141 taaaaaatga taaaatgggt acaagaaaag acatcatgag aggttatctc catgaaaatc
    19201 ttttcctgtc acatgcctca cgctcagact cgccaaagtt ttgagagcgt ggggcttttt
    19261 ttgtttgcaa ttatttccat tttggaaaca gttggtttta ttctttcgat aagtgttgtt
    19321 gaagaattaa ggccacgttg gctttctctt cctctgtcat aggaggttcg tttggatcgt
    19381 ctaccgaaaa ctcgatagca tgccatttat catttactct aatccactct cttcgtctgt
    19441 ggcatttgca atctaggttg tgtttaatca cttccatcgg tctactttcg ttactcattt
    19501 tatttctctc tatacacact gacaacttcc ccaatagttc ggatgtcgtt gctttcgtct
    19561 aggtgtatat cctcataatc tggattcaag ctttccagat atccctgacg cagtttctta
    19621 acatagttag cgccgtctac ttggaagatg ccgatagtgt tataatcaac ctgttgggta
    19681 ttctttataa aaagatagtc accattcttt atctttggct ccatagagtt gccgacgaca
    19741 taagcgatag cgtcgtagtc gtctgggatt tcatcctcat agaacgaaac ctccatatct
    19801 aaatcgtcgt cctgtatcga accactacca gcagagacaa ccccagtaac acgtcggtaa
    19861 gtagtctgtc tgtagtcgtc cagtctgatg atgttctccg atacttcgtt tatcttcgtt
    19921 tcttcttcgt tttcttgact ctccagaagc tcctcagatg tccgtagcac gattttttta
    19981 ttgtcagtat ttaattttcg agctgtattt gtaatttctt ctaaaaggga gtctgacggt
    20041 tgtgcggtaa aaatcttgtt ttcgataagg tcagatttat ttatattaaa atagtttgcc
    20101 aaaagttcaa ttttaccaat acgaggataa gttattcctt tcagccagtc gcgaactgta
    20161 gtgtatttta aatccaagtc tgcacataat gtatttctgt ctaccccttt ttgctccatg
    20221 taaaaactta gattattggc aaaaatttct ttattttcga ctttcatttc cgcccctcct
    20281 tatatagtat attttacggc aaaaacgcaa aaaagtaaag aataaaataa aaaattgcga
    20341 aaaaaacgca aaaaacactt gacattgcgg ttaaaccgca gtataatata atcaagctta
    20401 aggaaataac aaaccggagg gaaacaccat gaacacatta aacgagaaag caatcaacat
    20461 cttcaaagca gtagctaagg aaactttaat ccaaggtact tacgaggaaa acttccttta
    20521 cagccagctt gaagcattct gtactaactg ccgtcaattc gcttttggat ggacagagtt
    20581 agcagaggag attgaacgcc aagagcgtta ccttctcgat tctggtttca ctcaagagga
    20641 aatcgatgac attcgttttg atgtagcatt tgcaggaatg cttgataaat taaatgtagc
    20701 ctgattggta tcaccaaggt tcgaatcctt ggcaggttgt tgctccaaga gcaaaataaa
    20761 aaagacaagg aggtgggaag atgaacgaac tagaaagaac agccctcaat gagatattga
    20821 ggaccgtgac atatattgct gagaaagtgg acgaactaga ttctaagatt tctttgaacg
    20881 attcacaagt tcctgagcaa taaaaaaagt cttaacctac tttacactag gtcaagactt
    20941 gcacactttg ataaggtttc acagtcggtg taaagcaact ggttgaaact tcgctggtca
    21001 tgcgtccagc actgcaatca acgtggtttg gctagtcttt gagtgtcgct cggtagttat
    21061 ctgtcagtcc cgctataagc agagctgcag tccctcttat agtcagcgac aggctccgtg
    21121 cagtcacact cgcagtaaaa acgcgttggt tacctagcca aactgaatca ctgaaccaca
    21181 gtccccttca aaaattttgc caatttgcat cagctccttt cttgttaagg ataatataaa
    21241 tatatactgt ttttgaaggg gttacatcgg tcttaagacc gatttttgga gacggtcatg
    21301 gaagataaaa tcatcgaact tgctgattac ttcatcagcg aatctacaac gtacagagaa
    21361 gctaaaatag cgtgtgagaa gctattgaaa caagtcagcc atgagataga actcagggcg
    21421 atggaaagta ggacagtatg aaagaagcag taaaggaatt tctaaaattc aggagccgat
    21481 ttacaaaaat agaatggttt gaaattaacc aagctatcga agctcgttta aatcaaaaag
    21541 ccgaccagtt gaaactggac gacttagatt tagaaatcat ttctagcaga ctagaaaaag
    21601 ttatctagaa acgatttgaa tgaacattgg atggatacga tagtcagcgc cacgatagtg
    21661 aatgtagata taatcctgat ggtacatcga gtttgcttca ggtttagaaa ttggtgagta
    21721 gagttctgca ttttcttccc accaaatgta aggattagcc atatttggtc ccattacaca
    21781 atcgtcgtcg gctgataggt tcacccaatt tccgcaaaga catgcgtgaa tttcagtcat
    21841 aacattccct cctttctgac tacattatag cagaattgcg aggaacaaat agaaaaataa
    21901 ggaggtagga acgtgtcgaa aatgacatta aaaacactaa gaacactcaa aaactggaga
    21961 caaagtgatg cggcagcagc tgtgaatgta tcagttgata catgggggca ttgggaacgt
    22021 gggataacag agcctagtgt ttcgaaagca tatcaaatcg ctagtgtttt cgatgtatca
    22081 gtagatgata ttattttttt acctgatatt gcggtttaac cgtaacaaaa aaatagaaat
    22141 ggggaagaat gattgaaaat aagtggagag aaaggggatt aaatatgagg tatgcagtat
    22201 ataatcagga atactcatgg gaattacaca tctttgaata atgcttatgc tcaagacaaa
    22261 cgtttaaagg caacaacgat aggtatcctt acagtaatct tgatgaataa gtctgattgg
    22321 gttgtgtatc ctgacgagat tgcacgacgt ctaggaataa gcaggcgcac cgtagatgag
    22381 cactttaagc ttttagagaa agcaggctat ctcagagtat atcgcttagg gttaggcaga
    22441 ggtaaaggcg taacggtata tagatttttt tcagatatgc ctatttcaga tgactacttt
    22501 gagtatctaa aaactaatct tgagaaagag ttatccacag ataacggagt ttaaaaatac
    22561 agttggaaaa tattgccatg tgtaaaattg ccatgtgtaa aattgccatg tgtaaaattg
    22621 ccctctaata agtactaact atacaacaag tactaactat acaataatct aagcctaacg
    22681 gcactaactt agtaataact actaacttac aacaaactaa tacttctcta aaaaataaaa
    22741 gagagaaatt tcaattttag gactttgaaa aataggaaag gagaaaaaat gagaccaaga
    22801 cgatatccgt atagtgggaa aaaagagtcc acctttgtaa aggccgaccc tgagttagtt
    22861 gaaaaacttt taagaaacac tagttttctt gagtgtttac aaaaaaagcc tatcaatttt
    22921 cagatagact tagaagaatt taagcgtctt agctatgaag ccattcatga tacttctcaa
    22981 gtaactcaat aggaggaagg aataaaagga atactatgaa cgaactcatc aacgtaaccc
    23041 tgaatgacaa tcaggagcca gtagtgtcag gaagacaact acatgaggcg ctgggtgtta
    23101 attcaagata tacaacatgg tttgaccgta tgaaggaata cggatttaca gaaggtcagg
    23161 actttctccc aaatttggga aaaagtacag gagggcgaca agctactgac cacatcatca
    23221 agctagacat ggccaaggaa attgctatga tccagcggac ggagagaggc aagcaagtcc
    23281 gacaatactt tatccaagta gaaaaagact ttaatagccc tgagaaaatc atggcaagag
    23341 cattgctcat ggctgatcag aaagtccaca agctagaggc tcagattgag gctgaccgtc
    23401 ctaaggtgct atttgcagac gcagtaagtg caagccatac atctatcttg gttggcgaac
    23461 ttgccaagct cattagccaa aacggctaca aaatcggtgc caatcgcctc ttttcttgga
    23521 tgcgcgaaaa tggctacctg attaagcgca aaggctcaga ttggaacgtg ccaacccaac
    23581 gtagcatgga cttgaaactc tttgaaatca tggaaacaaa cgtgcaacac gcagatggac
    23641 atatcactgt gaacaagaca ccaaaggtca caggcaaagg acaacagtat tttatcaata
    23701 agttccttaa tcaggaatac ttgacaggat aaaaacaaaa gcccctctgg aacggcaatt
    23761 ccattgaggg actaagcaaa atactttacg aggtaattat atcatgaaaa cagtaaaaaa
    23821 ggaatgggag ccacggattg taaacatcat ggcagatggt tctcaagttg atgatttgac
    23881 aggctatgtc atccctgctg gtcattcgta ctatgacatt attttaggca tgaacaagca
    23941 atctaacgag gagggcgtag cttaatgaaa ttacttacta aattaaaact cagactcgaa
    24001 ggtgttatta aatcagtcaa ccttgactgg agagaggttg ctattgaggt tagcaatgac
    24061 cttctcgaag agcgcaaacg tcgctttatg cgtgagcaag aaaaccatga cttgaagcag
    24121 gagcttgctg cctacaagta caaagaaaac tttgatatca aggctagact gcaaggagaa
    24181 atgtagatgt acattatatc gatttatgtc aagaatactg aaactggaaa cgaggatttc
    24241 agtttgattg gacgtgattt cttaccgacg gggcaccaag actatattgc aagagttttt
    24301 ggaataaaag aagaagcgat tgattactta aaatctatat cttacatcgc atcaggtgtt
    24361 catggtaacg attgggttta tcaaaatgaa aaactaccag aaattgagtc acgttgccga
    24421 atttggaaag taggagaata aaaggagaac aatatgttta aagcactaaa aacaatcaaa
    24481 aaaatcaaac agcttcagaa agaaatgcac gatgtcagtt tagcctttct ggctctacaa
    24541 gatgtcggat tgatgccaga gactgaaaga agcaaggcga aggctcaaac aatgcacgat
    24601 gtaagccaca tgctcaagga cgtcctgggc ggcaagtcgg tagatgaagc catgaaacgt
    24661 ctaaatagcg aagtgaaaat tgaagaggtg gagcaggaag atgacaaaga ttgaaattga
    24721 aaaccgtgtc tggcttttgg ccaatcatga agaaaaaaac gaattgctgg agcttgggaa
    24781 ggtgtatgct catgtttgat tatgacagag atataatgca accgcctgaa gaacgagaag
    24841 aacgtgaccc agctgattgg attttcagcg ctggtcaatg gatctatgta ggagattgtt
    24901 agcctatgaa tagagaacac aacgaaaggt agaaggaaat gacgaataat caaattgtag
    24961 aagcaaaagg cgacttttta accaacccac agctacttaa tagcggtatt atcagaaagt
    25021 atcttgaccc acaaggaaaa gctagtgatg aggagcttgc ctattttata gctcaagcca
    25081 aagcccaaaa cctcaatcca tttacaaaag aaatttattt tatcaagtat ggaactcagc
    25141 cagcccagat agtcactgcc aaatcagctt ttgaaaagaa agcagatagt cacccgcaat
    25201 ttgatggcaa agaggcaggc gtaatctatc tgatggatgg tgaaattaaa tactcaaaag
    25261 gagcatttat tcctaaaggt gctgaaattc ttggcggttg ggctaaggtg taccgcaaag
    25321 accgtactta cccaacggaa acagaagtat cttttgagga gtacgacaat tctaaaatac
    25381 gtgcaagagt taaggaactg acacaacaag gtaaagatgt tacttatcca gtgatgaact
    25441 catacggtaa gccaataggt gagaataact gggatactat gccttgtgtc atgatacgaa
    25501 aagtagctct agtgtcagct taccgtgagg cgtttcctgc cgagcttgga gcaagctatg
    25561 aggctgacga aattcagctg gataacacac ctaaagacgt cactcctcaa gaaagccgtg
    25621 aggatgtcgt agcacgcaag atggctcaga ttgagcaatt caacaaagag caagaggcaa
    25681 atcatgcaga tcctgaacct gctaaaactg aggagccaat ccagggcgag ttgctagacg
    25741 gtgaacttga atattaggag gacaacatgc aagaattaca ggttattgat gataagaaaa
    25801 tcaataaaat ctatgagatg atcacaacgg atgaacttac tagagagtct tttgaaaaag
    25861 acctcataga ggctactgag aagtacaagg actatattcc tacagctgga actctcaaag
    25921 acgacaaggc aaagcgggct gaatttaaca agttaattga gtctaaaaat cgtatccgca
    25981 ttgacactaa aaacttacta tcagagacag ctaacacatg ggatagttat gctaagtcaa
    26041 ttattgaccc atttgcaacc gtagttagtg aatttgacaa aggtatcaag gaaatcgaag
    26101 aacatcaaag acaactaaaa atagatacgg ttaagagtta cctagccaac aaatcggctg
    26161 agtacatgct ggaccctcgt ctctttgatg aaaaggccct tgagtatgtc aaggctggcg
    26221 atttcatggc agacggcgtg acgcttaaaa aagccactat gaagtcactt gatgacatgg
    26281 tcacatttga gtttcagaaa caacaagaat ttgaaaaagc caagtcagct atttcagggt
    26341 tatgtgctga gtacggcatg actgactcac cttacattag acagctgaaa gacttgactc
    26401 ttgctgaagc ctttgaacaa atcaaagctg attatgagtt tgaaaaacaa aaggaagaaa
    26461 tcagacaggc tcaagaacga gcagagcgag aaagtcagga acttttagca gcccaacaaa
    26521 ccaaacagca agaacgggct ccaaaatcaa cgggaacccc aaattttgac ccagaggcag
    26581 gcgaaatctt ggacggtgag caaatccctc aaaatgagca gaactctctt agaggggctg
    26641 aaaatgacct aaaacgatat acccaaaaaa tgactttaga ggtgtatttt gtagacacag
    26701 ccgaaaaaga ccgtttcaag gctggtctaa gtcaactcgg atttgatttt aaaaagaact
    26761 atcaagtcag cggttatcaa cgtattgagc cattgactca ggctgaactc aatgagcaat
    26821 ggggaggtaa ccatggacat cagaaaaata tctgacagcg tagccatcta ctcggacggc
    26881 aagaaattgc atgttatcca caacctaggg gatgagttta tcctagattt taaggtggga
    26941 gaggatagcg tctggaacct caatggccaa gtcgtagaaa ttattgacat gattgagcct
    27001 gtctttaaag ttttcagctt ttgctcaaaa tctggagagg gtatgcaacg cttaaaacat
    27061 gctatcgtcc actttgaaat atttgagcag tacatcagag ataatcagga agacctgatg
    27121 atctggtggc acaatccagg aggggaatat gattaaaacc gtattttttt catgtgatta
    27181 tccacatcat gaggcgattg acgaccaaat aaatagctgg cttgccgaaa atccaggcat
    27241 taagttgatt gacatcaaat ttcaatcaaa tgtgtctgct gtcgctgaca gtggagtcag
    27301 tgctgaatat tggcatacat ccgcattgat tatttacaaa gttccctcag agaacaatat
    27361 aagcagtatt aattcaaatg gtttaggttt cataatcagc tgtgagaaat gtggtagctt
    27421 atcaataatc aagggaaaag atgtaggtca aaatgtatgt tatgaatgca aaggagagaa
    27481 ataatgaatg attttatcaa agagattggg atggctatcc tatggatgtt tttagggtat
    27541 ctcttgggag agcgtagcac tagaggggga caaatcagat gatcaataac gtcacactgg
    27601 ttgggaggct tgtagcgcct cctgatctac gaaaaacgcc taacaatgta tctagcttgc
    27661 agggcacgct tgcagtcaat cgcaatttca aaaacgaaaa tggagagcgt gaggctgatt
    27721 ttatcaattt taaagcttgg agaggtacag ctgacatcat tgctcagtat tgcagcaagg
    27781 gctcacttat tgggatcatt gggcgcttac aagttaggtc ttacgagaaa gacggtcagc
    27841 gtcgatatgt gactgaagta atcgctgaga gtgtagctct gctagagagt cgcaacagtc
    27901 agcacggaca aggcaacagt ttccaaaatg ggaatagctc accttttacc gatcctaacc
    27961 cctttgacct cccaaatgac ggtttgccgt tttaggaggg acagttagtg gaaatagata
    28021 agattataaa aaaagatgtc ttggaattta tggaaacaat tcctgataat aaaattgatt
    28081 taatcgtaac agacccgcct tatttgataa attataaaac aaattggcgg aaagaaaagc
    28141 ataaattttc aaatgttatc aaaaatgata acaatcctga attgataaaa gagtatataa
    28201 aagagtgtta tcgaatttta aaagatgata cggctattta tatattctgt tcatttgaca
    28261 aggttgattt ttttaaaaaa gaaattgaaa agtatttttc agtaaaaaat attattatat
    28321 ggcgaaaaaa taatcatacc gctggcgatt tagaggcgca gtttggaaaa cagtacgaga
    28381 tgattatatt ggcaaacaaa ggacggaaga aattcaacgg tgagcgactg acagatgttt
    28441 gggatttcaa gagagtaagt tcagataaac tactccatca aaatcaaaaa cctattgaat
    28501 tgataaaacg atgtattgtt aaacattctg atgttgggga tactgttttt gatggtttca
    28561 tgggaagcgg tacgacagca ttagcagcgt tagaaacgga taggcatttt ataggaactg
    28621 aaatagatga atattatttt ggtatagcag aggagcggat aaaaaaccac aacgctcaat
    28681 taagtttatt tgatgaggta tgagatggag tggacggatt gggtggattg gaaacctgaa
    28741 accaaaacgg acattaaaac caaaattgaa aatgacgggt acacttttcc acactatgac
    28801 aagaaaaaca acggcgtcaa gtacgtcatc tctacactgg acatcaaacg agactgtcta
    28861 agacttggag taccgtttga agatgtgtac cctttgcaaa cgacactttt ttaacaggag
    28921 aaagaacatg gcaagtaaaa tcaatgcgac agaacgtatt gctatcatca ttgataaaca
    28981 aaaaatagag gtcgttacga ctctaaacta tgatatgagc attagctttg ataacaaaga
    29041 cacggctcct acactagatg acaatggtga cctttttgaa ccggtctaca agtgcaaagt
    29101 taaggcaatt cccaaaaatg atgtattttt cacctcatta acacgagtca agagcaacat
    29161 caagacgcta caagaggtta aaaaattctt tgagttcgta aacgaaaaca gagaaaatct
    29221 ctttgagatg gcaggattta agggggctct tgaatgaaat tgaccctgaa cattgagcct
    29281 aaacctcaat cacggccaag gtttgcaaga cgtgggagtt ttaccacaac ttacgaagac
    29341 aaggatatga aaacatggcg caatcattgc cagctgctca ttgctaatca gtacatgggt
    29401 cagcctatcc ttgagggagc tttgagggca cggcttagat tttatatcaa acctcctcag
    29461 tacatttcta aagtcaagaa gaaccaacag gccctcctgg atgaaattat accagtaggc
    29521 aaaaagcctg acatagataa ctacgaaaaa gcgctatatg acagcatgtc agggatcgtc
    29581 ttccaggacg acggtcagat agcgctacat gatgtaggca agttctacag tctaaatcca
    29641 cggatagagg ttgagattga ggtcatgaaa tccctgagta tttgaagaaa tgaggagcag
    29701 atggctgact acgcattata tcaaggtgat gtgtttgtta cgcttggaac attagcgcag
    29761 atcagtagcg agacaggaat tactgaaagg atgttaaagt attacactta cacatcacac
    29821 caaagacgac acccaaacgg tagggccgtt attaaaattg aggaggaaga taatgagaat
    29881 taagacggaa agtgaagaag ttggaagatg atggaagagt taaagcaaaa agttaatgaa
    29941 gtatacaact ggacggtaga agacgggaag ccgcaacctc ccaagcaaga tttaccacaa
    30001 gcggtgaaag accgggcgga ctatttttgg gaaatggcag aagatggtat gacgtttatg
    30061 ggagcgatgg aatgcatctt tgctgatgaa aagcctacag actatgattt gggagctact
    30121 aagggttggt tgccaaaatc taaggagttt gatgattgga ttggctattc gccaagcatg
    30181 gctcaggtag ttattgcagt ttatttgatt tatggaggaa actaagatga ataagcagga
    30241 attgattgag aaatataaaa aacttgaggg tgtatggaat gctgaaggag cagaactagc
    30301 tcgtcaaatt tttctgcaag acttggaaca actagataaa ccaaaaccag tcaaagttcc
    30361 gcagtgtgtg gcggaatata tagaatttaa aaagaaaaac aattttcatg tttacggtgc
    30421 aatgagagta attgaagatc attatgataa gaaagttcct gagtggtttt acgaaaataa
    30481 catcgaaaaa ttctgtcttg cttggcttga cggctacgag gttgaaaaag agaagcggta
    30541 tttggtgact ttaaaaaata ggcagccttt ggtcaaatcg caatcaggga gtactcttta
    30601 ttttagtcaa gatataacag ctaggaatta taaaggtact caaaaagaac tagaagacgc
    30661 aaacttcggc tgggtgtttg attgtccagg gattgagatt gaggaggtgg agtgatgagc
    30721 cttacgctaa atagcacaat tggagactta gttttggcaa tcggagaaat tatcgttggt
    30781 tctgatggta aaaccactac agcgatactg gagatacctg atcaaagctt ttacttagag
    30841 attgagctta aattgaagga ggaggtcata aattgaaacg attcatagct atctggattc
    30901 tgctatctgc tggattgaat atctggcaga gtatctacat taaaaagtta gaagaaaagc
    30961 gcccgattgt cgtctataaa gctgataacg caggcgctga gatattcggt aaagtcgtcg
    31021 agaaaggacg gcatggcaag ctatatacgc ttaccattcg tgactacggg gtgttcgtgg
    31081 ttacgaagga cgtgtacgat aaagtgaaag ttggggatga ggtgttacta tgacagaaac
    31141 tattaaacta ccagactatt atgagcctga ttggaaaaat gcaaggtacg ggtcgttgga
    31201 agagcttaaa gaattgttgc tctttaagcg tattgtgaaa tgggataagg actttttgct
    31261 gcttgaagac ggcacaaagg tcactattga aatgtctgaa agtgattgct gtgcctcagc
    31321 aggtggggag ttccaagatg tatcacttga cgctgtgatt actaatattg aaattggaga
    31381 accggaagaa atccccgacc attggggaac tggttataaa aacaaagtaa ctatcttcca
    31441 taatcagaac cctgtagcta ttgccaattg tgaagcagag cataacggct attattacag
    31501 cgtatgctct ttagtgattg gtgatattca ttttccagtt gttaatgctt aggaggattt
    31561 aacatgacac caagatatag agcgtggata aaaacagaaa aacgtatgtt tttttcagat
    31621 gacattcttg ctattgacta cgaaaacaaa gaaatagtga cacaacaagt ttattttgag
    31681 aatggtttac cagacgatag agatatctat tgttatgatt ttgacgaaat cgaactcatg
    31741 caatcaacag gactcaaaga caagaacggc aaggaaatct ttgaaggcga tattgtacga
    31801 actactagat ttttgggtag agctgacgaa attggcggtt tctatgagta tgacaaggaa
    31861 tttataggga ttgttaagca gcttgagggt tcttgggtaa ttgatacggg cagtgacgca
    31921 gtatgtttat ggactgaaat tgaagaaaat gaaatcatcg gcaacatcta tgaaaataag
    31981 gagtttggag gacgcaaatg agaccttgta aatatccata ttcaggaaga agaaaaaaac
    32041 aagaaacgcc gtcgccaata ttttctgcac gaccaatttt tgacgaagtt ccaattgtag
    32101 aagaagttaa ggttgagttc ggagttgaag ctagtatggg gcgcatatat ccagaaacgt
    32161 taatacattt agatatttct ggatacggaa atagagtgca ttcagtacat cgcttccccg
    32221 gtattttact gagtgttggt gagtcaatcc aactaaagat gcttttctat aaaagactta
    32281 gaaattttac tacagatcgt ttcttgacgt ttagagaatc tgattggaag ttctttatcc
    32341 gggacctggt caacgaattt aagcattaaa aaaagccaag acactctctg cctcagctaa
    32401 tagttctcgc aaagactatt atatcacaaa ggagacagag agtgaacaag gctaaagagc
    32461 tcttgaaaga gttgcaggat ctggacatgg acatccaaag ccgtatagac gaaattaacg
    32521 agcttgaggc aggtttgctc tcaagcccta aatggtccga ggttaaagtc caaggtggac
    32581 agactagaaa agttgatgat gtctatactc agttggtagt gatgaaagag gctatagagc
    32641 aggatactaa agaggtcatt aacagaaaac ttgaattagg tagaatgatc aataggctta
    32701 aaaatccaaa gtacagggca gtattaagaa tgacttacat caacaaaggc accgctgata
    32761 gcgtttgtta tgatttgaat atgagtcgta caacctacta caggttaaaa aatgaggcgg
    32821 tcttagcttt ggaagaagtt atctaacctc atagtgagct tatgggactt tttggaacag
    32881 cacggttcta aaaatctgtt agaatggtag tatcaagaat tgaaaagaga ggtctcagaa
    32941 ttggtagatg gttacctgta atgtcagggg gctgtaatgg ccttggaggt tcaagtcctc
    33001 ccctctcctt tgagtgtttg tgtcccagaa tgagttaaat cttctgggtg gggattcaca
    33061 tatcactcat taactcctat cactcattaa cttaaaaatg gttgcggaag cgactggacc
    33121 tcgcatgatt gcgtagctaa ttatattccg gataagttat aagctagagg gtttgattcc
    33181 ctcagaggtt ttaaagacta caaaaaataa aaaagaagtc aaaatttaat acgcacgcaa
    33241 ggtagtagtc gccttgcaag aaggtcgcac atcgtgtggc ttttttgatt gtttgaaagg
    33301 tggtgatgga aaattgagtg gattgagaat aaaacaaaag agatttgcag atgagtacat
    33361 catctcaggt aatgcgacgg aagcctataa gaaagcaggt tatcgtgttt ctagtgatag
    33421 agtggcaggc gttgaaggac ataagttact aaagaatcct aagattaaaa gctatataga
    33481 tgaacgactg aaacagcttg attctgaaaa gattgcggat cagcaagagg tcttaggtta
    33541 tctaacttca gtcatgcgag gagagacgca agaacagacc ttgataagca ttggagaact
    33601 agggcagacg attacggata ttgatgttgg agcaaaagac agaatcaagg cagccgaact
    33661 attaggaaaa cgtcataggc tttggacaga caaagtagag gcagacgttt ctggaacggt
    33721 ggtgtttgca aatgagtcag acataccaga ttaaacaaag tgatattgta atcgacctac
    33781 ctaagacagt aggagctggg tacggacagt tctggcgctc aagaaatctt tatcgtgttg
    33841 taaaaggttc ccgtggttcg aagaagtcca agacaaccgc tttgaattat gttatccgtc
    33901 ttttgaagta tccctggggc aacttgcttg ttattcgtag atactcgaat accaacaagc
    33961 aatcaactta tacggatttt aaatgggcgt gtaatgtgtt gggtgtgact catttgttta
    34021 aatttaacga gtctttgcct gaaataactg taaaagcgac tggtcaaaaa atactgttcc
    34081 gtggtttgga tgatgaactc aaaattacat ctattacagt cgatatcggt agtctgtgtt
    34141 gggcatggtt cgaggaagca tatcaaattg agactgaaga caagttcagc acggttgttg
    34201 agtctatccg tggtagctta gatgtacctg atttctttaa acaaatcaca gtcacattta
    34261 acccgtggaa tgagaggcac tggctcaagc gtgtattctt cgatgaagag acgagacggg
    34321 ctgacacatt cgctactaca accacttata aatgcaatga gtggcttgat gaagtcgata
    34381 tcaaacgcta tgaggatttg tatcatacga accccagacg tgctagaatc gtttgtgatg
    34441 gcgaatgggg agttgctgag ggtttaatct atgaaaacgt gactgtcaag gatttcaata
    34501 aagatgaatt actacaagat tcagctaata aattatgtat cggtcttgac tttggtttta
    34561 ctcatgatcc aactgctttg tgttgttcgt tgataaatga tacgacgaaa gagatttatg
    34621 tctttgatga ggcgtataaa gtcggattga taac
//
LOCUS       DAVLIK010000018        34642 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLIK010000018 DAVLIK010000000
VERSION     DAVLIK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.018"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            369..3029
                     /gene="rrgA"
                     /locus_tag="VXE87_001003"
     CDS             369..3029
                     /gene="rrgA"
                     /locus_tag="VXE87_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus tip adhesin RrgA"
                     /protein_id="HEV0842563.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTNGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQRTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTVYERKDKSVPL
                     DVVILLDNSNSMSNIRNKNARRAERAGEATRSLIDKITSDPENRVALVTYASTIFDGT
                     EFTVEKGVADKNGKRLNDSLFWNYDQTSFTTNTKDYSYLKLTNDKNDIVELKNKVPTE
                     AEDHDGNRLMYQFGATFTQKALMKADEILTQQARQNSQKVIFHITDGVPTMSYPINFN
                     HATFAPSYQNQLNVFFSKSPNKDGILLSDFITQATSGEHTIVRGDGQSYQMFTDKTVY
                     EKGAPAAFPVKPEKYSEMKAVGYAVIGDPINGGYIWLNWRESILAYPFNSNTAKITNH
                     GDPTRWYYNGNIAPDGYDVFTVGIGINGDPGTDEATATSFMQSISSKPENYTNVTDTT
                     KILEQLNRYFHTIVTEKKSIENGTITDPMGELIDLQLGTDGRFDPADYTLTANDGSRL
                     ENGQAVGGPQNDGGLLKNAKVFYDTTEKRIRVTGLYLGTGEKVTLTYNVRLNDQFVSN
                     KFYDTNGRTTLHPKEVEKNTVRDFPIPKIRDVRKYPAITIAKEKKLGEIEFIKINKND
                     KKPLRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENS
                     EPAGYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREY
                     PRTGGIGMLLFYLIGCMMMGGVLLYTRKHP"
     gene            3252..5249
                     /gene="rrgB"
                     /locus_tag="VXE87_001004"
     CDS             3252..5249
                     /gene="rrgB"
                     /locus_tag="VXE87_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus major pilin RrgB"
                     /protein_id="HEV0842564.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAAGTTTTSVTVHKLLA
                     TDGDMDKIANELETGNYAGNKVGVLPANAKEIAGVMFVWTNTNNEIIDENGQTLGVNI
                     DPQTFKLSGAMPATAMKKLTEAEGAKFNTANLPAAKYKIYEIHSLSTYVGEDGATLTG
                     SKAVPIEIELPLNDVVDAHVYPKNTEAKPKIDKDFKGKANPDTPRVDKDTPVNHQVGD
                     VVEYEIVTKIPALANYATANWSDRMTEGLAFNKGTVKVTVDDVALEAGDYALTEVATG
                     FDLKLTDAGLAKVNDQNAEKTVKITYSATLNDKAIVEVPESNDVTFNYGNNPDHGNTP
                     KPNKPNENGDLTLTKTWVDATGAPIPAGAEATFDLVNAQTGKVVQTVTLTTDKNTVTV
                     NGLDKNTEYKFVERSIKGYSADYQEITTAGEIAVKNWKDENPKPLDPTEPKVVTYGKK
                     FVKVNDKDNRLAGAEFVIANADNAGQYLARKADKVSQEEKQLVVTTKDALDRAVAAYN
                     ALTAQQQTQQEKEKVDKAQAAYNAAVIAANNAFEWVADKDNENVVKLVSDAQGRFEIT
                     GLLAGTYYLEETKQPAGYALLTSRQKFEVTATSYSATGQGIEYTAGSGKDDATKVVNK
                     KITIPQTGGIGTIIFAVAGAVIMGIAVYAYVKNNKDEDQLA"
     gene            5305..6486
                     /gene="rrgC"
                     /locus_tag="VXE87_001005"
     CDS             5305..6486
                     /gene="rrgC"
                     /locus_tag="VXE87_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HEV0842565.1"
                     /translation="MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQL
                     PSRDGHRLQVWKLDDSYSYDNRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSH
                     IPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKADTVTTKVKLIKVDQDH
                     NRLEGVGFKLVSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIFVTNLPLGNY
                     RFKEVEPLAGYAVTTLDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGA
                     MFKVMKEESGHYTPVLQNGKEVVVTSGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTS
                     PVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKPN
                     N"
     gene            6824..7726
                     /gene="srtC-1"
                     /locus_tag="VXE87_001006"
     CDS             6824..7726
                     /gene="srtC-1"
                     /locus_tag="VXE87_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HEV0842566.1"
                     /translation="MVKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPVIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQPEKALKALKAARKEVKVEDGQQ"
     gene            7713..8606
                     /gene="srtC-2"
                     /locus_tag="VXE87_001007"
     CDS             7713..8606
                     /gene="srtC-2"
                     /locus_tag="VXE87_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HEV0842567.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAVAIYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTEQEKKKGVSEYAN
                     MLKVHERIGYVEIPAIDQEIPMYVGTSEEILQKGAGLLEGASLPVGGENTHTVVTAHR
                     GLPTAELFSQLDKMKKGDVFYLHVLDQVLAYQVDQILTVEPNDFEPVLIQHGEDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLAALVMILVLSYGV
                     YRHRRIVKGLEKQLEEHHVKG"
     gene            8593..9444
                     /locus_tag="VXE87_001008"
     CDS             8593..9444
                     /locus_tag="VXE87_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEV0842568.1"
                     /translation="MSKAKLQKLLGYLLMLVALVIPVYCFGQMVLQSLGQVKGHEIFS
                     ESVTADSYQEQLQRSLDYNQRLDSQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLAMGLAHVDGTPLPVEGKGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(9517..10793)
                     /locus_tag="VXE87_001009"
                     /pseudo
     CDS             complement(9517..10793)
                     /locus_tag="VXE87_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(10908..11048)
                     /locus_tag="VXE87_001010"
     CDS             complement(10908..11048)
                     /locus_tag="VXE87_001010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842569.1"
                     /translation="MKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVDAFM
                     AL"
     gene            complement(11050..11334)
                     /locus_tag="VXE87_001011"
     CDS             complement(11050..11334)
                     /locus_tag="VXE87_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842570.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(12768..13991)
                     /locus_tag="VXE87_001012"
     CDS             complement(12768..13991)
                     /locus_tag="VXE87_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0842571.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYYKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            14159..15481
                     /locus_tag="VXE87_001013"
     CDS             14159..15481
                     /locus_tag="VXE87_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0842572.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            15483..17369
                     /locus_tag="VXE87_001014"
     CDS             15483..17369
                     /locus_tag="VXE87_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV0842573.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            17537..17881
                     /locus_tag="VXE87_001015"
     CDS             17537..17881
                     /locus_tag="VXE87_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0842574.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            17891..19303
                     /gene="lacG"
                     /locus_tag="VXE87_001016"
     CDS             17891..19303
                     /gene="lacG"
                     /locus_tag="VXE87_001016"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0842575.1"
                     /translation="MENLQFKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGDANILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLDRENIDHFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKTGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            19372..21051
                     /locus_tag="VXE87_001017"
     CDS             19372..21051
                     /locus_tag="VXE87_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0842576.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDTSAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QPISFVLLSLMLVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(21176..22615)
                     /locus_tag="VXE87_001018"
     CDS             complement(21176..22615)
                     /locus_tag="VXE87_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0842577.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLIFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(22619..23968)
                     /gene="trkA"
                     /locus_tag="VXE87_001019"
     CDS             complement(22619..23968)
                     /gene="trkA"
                     /locus_tag="VXE87_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0842578.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIEREHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            24157..25005
                     /locus_tag="VXE87_001020"
     CDS             24157..25005
                     /locus_tag="VXE87_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0842579.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            25020..25568
                     /locus_tag="VXE87_001021"
     CDS             25020..25568
                     /locus_tag="VXE87_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0842580.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            25575..25832
                     /locus_tag="VXE87_001022"
     CDS             25575..25832
                     /locus_tag="VXE87_001022"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842581.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDETDEVSSKQCFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            25934..27619
                     /locus_tag="VXE87_001023"
     CDS             25934..27619
                     /locus_tag="VXE87_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842582.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRII
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     ADTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            27604..28434
                     /locus_tag="VXE87_001024"
     CDS             27604..28434
                     /locus_tag="VXE87_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0842583.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQTLKKGDYITLLLATLFLVASLLLILQNQGRFYNPWK
                     "
     gene            28627..29130
                     /locus_tag="VXE87_001025"
     CDS             28627..29130
                     /locus_tag="VXE87_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0842584.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      29184..29418
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            29583..30146
                     /locus_tag="VXE87_001026"
     CDS             29583..30146
                     /locus_tag="VXE87_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0842585.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGFSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            30160..30786
                     /locus_tag="VXE87_001027"
     CDS             30160..30786
                     /locus_tag="VXE87_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0842586.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            30813..31202
                     /locus_tag="VXE87_001028"
     CDS             30813..31202
                     /locus_tag="VXE87_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0842587.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHFYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            31207..31655
                     /locus_tag="VXE87_001029"
                     /pseudo
     CDS             31207..31655
                     /locus_tag="VXE87_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            31783..32370
                     /locus_tag="VXE87_001030"
     CDS             31783..32370
                     /locus_tag="VXE87_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0842588.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            32760..34367
                     /locus_tag="VXE87_001031"
     CDS             32760..34367
                     /locus_tag="VXE87_001031"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0842589.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYIAFVTAAVENSN"
BASE COUNT        10600 a         5752 c         7666 g        10624 t
ORIGIN      
        1 ggagttttat ggcttatttt ttttattaga aaatattttt tatcaaatat tgtcgttcta
       61 taaaaaaata tgtgataaaa atatctattg tgatggaagt tgttttaatt tatactagga
      121 tagttaatag taatactata ctatactata ctatattgta tacaagtgtg tcattgccag
      181 gttgagaaga tagctataac gcacttttat acgcttttgc tacgtttgtt agtgaacgga
      241 ttaactcagt gagataaatt ttatcagaac ataagtaatc cgtttcttcg tgtatacaga
      301 ttgaaagtac ctatgaatca tagaaggatt aacttgttct atgaataatg cttaacaggg
      361 agacacacat gaaaaaagta agaaagatat ttcagaaggc agttgcagga ctgtgctgta
      421 tatctcagtt gacagctttt tcttcgatag ttgctttagc agaaacgcct gaaaccagtc
      481 cagcgatagg aaaagtagtg attaaggaga caggcgaagg aggagcgctt ctaggagatg
      541 ccgtctttga gttgaaaaac aatacgaatg gcacaactgt ttcgcaaagg acagaggcgc
      601 aaacaggaga agcgatattt tcaaacataa aacctgggac atacaccttg acagaagccc
      661 aacctccagt tggttataaa ccctctacta aacaacggac tgttgaagtt gagaagaatg
      721 gtcggacgac tgtccaaggt gaacaggtag aaaatcgaga agaggctcta tctgaccagt
      781 atccacaaac agggacttat ccagatgttc aaacacctta tcagattatt aaggtagatg
      841 gttcggaaaa aaacggacag cacaaggcgt tgaatccgaa tccatatgaa cgtgtgattc
      901 cagaaggtac actttcaaag agaatttatc aagtgaataa tttggatgat aaccaatatg
      961 gaatcgaatt gacggttagt gggaaaacag tgtatgaacg aaaagataag tctgtgccgc
     1021 tggatgtcgt tatcttgctc gataactcaa atagtatgag taacattcga aacaagaatg
     1081 ctcgacgtgc ggaaagagct ggtgaggcga cacgttctct tattgataaa attacatctg
     1141 atccagaaaa tagggtagcg cttgtgactt atgcttccac tatctttgat gggaccgagt
     1201 ttacagtaga aaaaggggta gcagataaaa acggaaaacg attgaatgat tctctttttt
     1261 ggaattatga tcagacgagt tttacaacca ataccaaaga ttatagttat ttaaagctga
     1321 ctaatgataa gaatgacatt gtagaattaa aaaataaggt acctaccgag gcagaagacc
     1381 atgatggaaa tagattgatg taccaattcg gtgccacttt tactcagaaa gctttgatga
     1441 aggcagatga gattttgaca caacaagcga gacaaaatag tcaaaaagtc attttccata
     1501 ttacggatgg tgtcccaact atgtcgtatc cgattaattt taatcatgct acgtttgctc
     1561 catcatatca aaatcaacta aatgtatttt ttagtaaatc tcctaataaa gatggaatac
     1621 tattaagtga ttttattacg caagcaacta gtggagaaca tacaattgta cgcggagatg
     1681 ggcaaagtta ccagatgttt acagataaga cagtttatga aaaaggtgct cctgcagctt
     1741 tcccagttaa acctgaaaaa tattctgaaa tgaaggcggt tggttatgca gttataggcg
     1801 atccaattaa tggtggatat atttggctta attggagaga gagtattctg gcttatccgt
     1861 ttaattctaa tactgctaaa attaccaatc atggtgaccc tacaagatgg tactataacg
     1921 ggaatattgc tcctgatggg tatgatgtct ttacggtagg tattggtatt aacggagatc
     1981 ctggtacgga tgaagcaacg gctactagtt ttatgcaaag tatttctagt aaacctgaaa
     2041 actataccaa tgttactgac acgacaaaaa tattggaaca gttgaatcgt tatttccaca
     2101 ccatcgtaac tgaaaagaaa tcaattgaga atggtacgat tacagatccg atgggtgagt
     2161 taattgattt gcaattgggc acagatggaa gatttgatcc agcagattac actttaactg
     2221 caaacgatgg tagtcgcttg gagaatggac aagctgtagg tggtccacaa aatgatggtg
     2281 gcttgctaaa aaatgcaaaa gtgttctatg atacgactga gaaaaggatt cgtgtaacag
     2341 gtttgtacct tggaacgggt gaaaaagtta cattgactta taatgttcgc ttgaatgacc
     2401 aatttgtaag caataaattc tatgacacga atggtcgaac aaccctacac cctaaggaag
     2461 tagaaaagaa cacagtgcgc gacttcccga ttcctaagat tcgtgatgtg cgaaaatatc
     2521 cagcaattac gattgcaaaa gagaaaaaac ttggtgaaat tgagtttatt aagatcaata
     2581 agaatgataa aaaaccactg agagatgcgg tctttagtct tcaaaaacaa catccggatt
     2641 atccagatat ttatggagct attgatcaaa atggcactta tcaaaatgtg agaacaggtg
     2701 aagatggtaa gttgaccttt aaaaatctgt cagatgggaa atatcgatta tttgaaaatt
     2761 ctgaaccagc tggttataaa cccgttcaaa ataagcctat cgttgccttc caaatagtaa
     2821 atggagaagt cagagatgtg acttcaatcg ttccacaaga tataccagcg ggttacgagt
     2881 ttacgaatga taagcactat attaccaatg aacctattcc tccaaagaga gaatatcctc
     2941 gaactggtgg tatcggaatg ttgctattct atctgatagg ttgcatgatg atgggaggag
     3001 ttctattata cacacggaaa catccgtaaa gtgtagaaat gataatatct atgttctgaa
     3061 cgatactttt aagaagtagc actcaagaag agatttaagt ttacttggtg aaaccagttt
     3121 tcttcgccaa gtaaaccacc attgaaaggg gagatgtttt cgaaaacttg cacagaaaaa
     3181 ggattattat tgtcatgtgt aattcattac attgctcaca gttgatttta agagataaat
     3241 aaggagaaat catgaaatca atcaacaaat ttttaacaat gcttgctgcc ttattactga
     3301 cagcgagtag cctgttttca gctgcaacag tttttgcggc tgggacgaca acaacatctg
     3361 ttaccgttca taaactattg gcaacagatg gggatatgga taaaattgca aatgagttag
     3421 aaacaggtaa ctatgctggt aataaagtgg gtgttctacc tgcaaatgca aaagaaattg
     3481 ccggtgttat gttcgtttgg acaaatacta ataatgaaat tattgatgaa aatggccaaa
     3541 ctctaggagt gaatattgat ccacaaacat ttaaactctc aggggcaatg ccggcaactg
     3601 caatgaaaaa attaacagaa gctgaaggag ctaaatttaa cacggcaaat ttaccagctg
     3661 ctaagtataa aatttatgaa attcacagtt tatcaactta tgtcggtgaa gatggagcaa
     3721 ccttaacagg ttctaaagca gttccaattg aaattgaatt accattgaac gatgttgtgg
     3781 atgcgcatgt gtatccaaaa aatacagaag caaagccaaa aattgataaa gatttcaaag
     3841 gtaaagcaaa tccagataca ccacgtgtag ataaagatac acctgtgaac caccaagttg
     3901 gagatgttgt agagtacgaa attgttacaa aaattccagc acttgctaat tatgcaacag
     3961 caaactggag cgatagaatg actgaaggtt tggcattcaa caaaggtaca gtgaaagtaa
     4021 ctgttgatga tgttgcactt gaagcaggtg attatgctct aacagaagta gcaactggtt
     4081 ttgatttgaa attaacagat gctggtttag ctaaagtgaa tgaccaaaac gctgaaaaaa
     4141 ctgtgaaaat cacttattcg gcaacattga atgacaaagc aattgtagaa gtaccagaat
     4201 ctaatgatgt aacatttaac tatggtaata atccagatca cgggaatact ccaaagccga
     4261 ataagccaaa tgaaaacggc gatttgacat tgaccaagac atgggttgat gctacaggtg
     4321 caccaattcc ggctggagct gaagcaacgt tcgatttggt taatgctcag actggtaaag
     4381 ttgtacaaac tgtaactttg acaacagaca aaaatacagt tactgttaac ggattggata
     4441 aaaatacaga atataaattc gttgaacgta gtataaaagg gtattcagca gattatcaag
     4501 aaatcactac agctggagaa attgctgtca agaactggaa agacgaaaat ccaaaaccac
     4561 ttgatccaac agagccaaaa gttgttacat atggtaaaaa gtttgtcaaa gttaatgata
     4621 aagataatcg tttagctggg gcagaatttg taattgcaaa tgctgataat gctggtcaat
     4681 atttagcacg taaagcagat aaagtgagtc aagaagagaa gcagttggtt gttacaacaa
     4741 aggatgcttt agatagagca gttgctgctt ataacgctct tactgcacaa caacaaactc
     4801 agcaagaaaa agagaaagtt gacaaagctc aagctgctta taatgctgct gtgattgctg
     4861 ccaacaatgc atttgaatgg gtggcagata aggacaatga aaatgttgtg aaattagttt
     4921 ctgatgcaca aggtcgcttt gaaattacag gccttcttgc aggtacatat tacttagaag
     4981 aaacaaaaca gcctgctggt tatgcattac taactagtcg tcagaaattt gaagtcactg
     5041 caacttctta ttcagcgact ggacaaggca ttgagtatac tgctggttca ggtaaagatg
     5101 acgctacaaa agtagtcaac aaaaaaatca cgatcccaca aacgggtggt attggtacaa
     5161 ttatctttgc tgtagcaggg gctgtgatta tgggtattgc agtgtacgca tatgttaaaa
     5221 acaacaaaga tgaggatcaa cttgcttaag taagagagaa aggagccatt gatgacaatg
     5281 cagaaaatgc agaaaatgca gaaaatgatt agtcgtatct tctttgttat ggctctgtgt
     5341 ttttctcttg tatggggtgc acatgcagtc caagcgcaag aagatcacac gttggtcttg
     5401 caattggaga actatcagga ggtggttagt caattgccat ctcgtgatgg tcatcggttg
     5461 caggtatgga agttggatga ttcgtattcc tatgataatc gggtgcaaat tgtgagagac
     5521 ttgcattcgt gggatgagaa taaactttct tctttcaaaa agacttcgtt tgagatgacc
     5581 ttccttgaga atcagattga agtatctcat attccaaatg gtctttacta tgttcgctct
     5641 attatccaga cggatgcggt ttcttatcca gctgaatttc tttttgaaat gacagatcag
     5701 acggtagagc ctttggtcat tgtagcgaaa aaagcagata cggtgacaac aaaggtgaag
     5761 ctgataaagg tggatcaaga ccacaatcgc ttggagggtg tcggctttaa attggtatca
     5821 gtagcaagag atggttctga aaaagaggtt cccttgattg gagaataccg ttacagttct
     5881 tctggtcaag tagggagaac tctctatact gataaaaatg gagagatttt tgtgacaaat
     5941 cttcctcttg ggaactatcg tttcaaggag gtggagccac tggcaggcta tgctgttacg
     6001 acgctggata cggatgtcca gctggtagat catcagctgg tgacgattac ggttgtcaat
     6061 cagaaattac cacgtggcaa tgttgacttt atgaaggtgg atggtcggac caatacctct
     6121 cttcaagggg caatgttcaa agtcatgaaa gaagaaagcg gacactatac tcctgttctt
     6181 caaaatggta aggaagtagt tgtaacatca gggaaagatg gtcgtttccg agtggaaggt
     6241 ctagagtatg ggacatacta tttatgggag ctccaagctc caactggtta tgttcaatta
     6301 acatcgcctg tttcctttac aatcgggaaa gatactcgta aggaactggt aacagtggtt
     6361 aaaaataaca agcgaccacg gattgatgtg ccagatacag gggaagaaac cttgtatatc
     6421 ttgatgcttg ttgccatttt gttgtttggt agtggttatt atcttacgaa aaaaccaaat
     6481 aactgatatt caatgtacat cattatgaaa aagatagcag gctgaaggga agaccagagt
     6541 actctgaggt gatgttaatc aggaatcatg gtgatgtggc atgaatcaca ataacggata
     6601 tgaggctggg cagattgtgc cagcctcatt gtgggttatt gtttgtaaaa cgataggact
     6661 ggtctggtaa tcattttagg aatggacagg actgggattc tgatttaaaa tggatggtga
     6721 atcagaaaga aatgagattt tctcgtttct cttagcagat aggattgtct gttaggaaaa
     6781 gcgataaaat gatgagtttg aagataaagg gatgctgata aaaatggtaa aaacaaaaaa
     6841 gcaaaaacga aataatctcc tattaggagt ggtatttttc attggaatgg cggtaatggc
     6901 gtatccgctg gtgtctcgct tgtattatcg agtggaatca aatcaacaaa ttgctgactt
     6961 tgataaggaa aaagcaacgt tggatgaggc tgacattgat gaacgaatga aattggcaca
     7021 agccttcaat gactctttga ataatgtagt gagtggcgat ccttggtcgg aagaaatgaa
     7081 gaaaaaaggg cgagcagagt atgcacgtat gttagaaatc catgagcgga tggggcatgt
     7141 ggaaatcccc gttattgacg tggatttgcc ggtttatgct ggtactgctg aagaggtatt
     7201 gcagcaaggg gctgggcatc tagagggaac ttctctgccg atcggaggca attcgaccca
     7261 tgcggtgatt acggcacata caggtttgcc aacagctaag atgtttacgg atttgaccaa
     7321 acttaaagtt ggggataagt tttatgtgca caatatcaag gaagtgatgg cctatcaagt
     7381 ggatcaagta aaggtgattg agccgacgaa ctttgatgat ttattgattg taccaggtca
     7441 tgattatgtg accttgctga cttgtacgcc atacatgatc aatacccatc gtctattggt
     7501 tcgggggcat cggataccgt acgtagcaga ggttgaggaa gaatttattg cagcaaacaa
     7561 actcagtcat ctctatcgct acctgtttta tgtggcagtt ggtttgattg tgattctttt
     7621 atggattatt cgacgcttgc gcaagaagaa aaaacaaccg gaaaaggctt tgaaggcgct
     7681 gaaagcagca aggaaggaag tgaaggtgga ggatggacaa cagtagacgt tcacgaaaaa
     7741 aaggcacaaa aaagaagaaa catccgctga tccttcttct gattttctta gtaggattcg
     7801 ccgttgcgat atatccattg gtgtctcgtt attattatcg tattgagtca aacgaggtta
     7861 ttaaagagtt tgatgagacg gtttcccaga tggataaggc agaacttgag gagcgttggc
     7921 gcttggctca agccttcaat gcgaccttga aaccatctga aattcttgat ccttttacag
     7981 agcaagagaa aaagaaaggc gtctcagaat atgccaatat gctaaaggtc catgagcgga
     8041 ttggctatgt ggaaattcct gcgattgatc aggaaattcc gatgtatgtc ggaacgagtg
     8101 aggaaattct tcagaagggc gcaggattgc tagagggagc ttcgttaccg gttggtggtg
     8161 aaaataccca cacagttgtc actgctcata gaggattacc gacggcagaa ctgtttagtc
     8221 aattggataa gatgaaaaaa ggggatgtct tttatcttca cgttttagac caggtgttgg
     8281 cctaccaagt ggatcagatt ttgacggttg agccaaatga ctttgagcct gtcttgattc
     8341 aacatgggga agattatgcg accttgttga cctgtacacc gtatatgatt aacagtcatc
     8401 gtctgttggt acgtgggaag cggattccgt atacggcacc aattgcagag cgaaatcgag
     8461 cggtgagaga gcgtgggcaa ttctggttgt ggttattgct agcggcgttg gttatgattc
     8521 tggtattgag ttacggggtg tatcgtcatc gtcgcattgt caaagggcta gaaaaacaat
     8581 tggaggagca tcatgtcaaa ggctaagcta cagaaattac tagggtattt gctgatgctg
     8641 gtagcattgg tgattcctgt ttattgtttt gggcagatgg tgttacagtc tttaggacaa
     8701 gtaaaaggtc atgagatatt ttcagaatct gtgacggccg acagttacca agagcaattg
     8761 caacggtcgc ttgattacaa tcaacgcttg gattcgcaaa atcgtattgt agatcctttt
     8821 ttggcggaag ggtatgaggt aaattaccaa gtgtctgacg atcctgatgc agtctacggc
     8881 tatttgtcga ttccgagttt ggaaatcatg gagccagttt atctaggagc ggattaccat
     8941 catttagcaa tggggttggc ccatgtggat gggacgcctc ttcctgttga gggaaaaggg
     9001 attcgttcag tgattgctgg gcaccgtgca gaaccaagcc atgtcttttt ccgccatttg
     9061 gatcagctaa aagttggaga tgctctttat tatgataatg gccaggaaat tgtagaatat
     9121 cagatgatgg acacagagat tattttaccg tcggaatggg aaaaattaga atcggttagc
     9181 tctaaaaata tcatgacctt gataacctgc gatccgattc ctacctttaa taaacgctta
     9241 ttagtgaatt ttgaacgagt cgctgtttat caaaaatcag atccacaaac agctgcagtt
     9301 gcgagggttg cttttacgaa agaaggacaa tctgtatcgc gtgttgcaac ctctcaatgg
     9361 ttgtaccgtg ggctagtggt actggcattt ctgggaatcc tgtttgtttt gtggaagcta
     9421 gcacgtttac tacgagggaa ataaaaagaa atgaaaggaa agctaaggct gttccttttt
     9481 ccggctcttt gtcaactgta gtgggttgaa aaaaagctaa gctcgagaaa ggacaaattt
     9541 tgtcctttct tttttgatat tcagagcgat aaaaatccgt tttttgaagt tttcaaagtt
     9601 tcgaaaacca aaggcattgc gcttgataag tttgatgaga ttattggtcg cttccagttt
     9661 ggcattagaa tagtgtagtt gaagggcgtt gataatcttt tctttatctt tgaggaaggt
     9721 tttaaagaca gtctgaaaaa taggatgaac ctgcttaaga ttgtcctcaa taagtccgaa
     9781 aaatttctct ggttccttat tctggaagtg aaaaagcaag agctgataga gttgatagtg
     9841 gtgtttcaag tcttccgaat agctcaaaag cttgtttaaa atctctttat tggttaagtg
     9901 catacgaaaa ataggacgat aaaatcgctt atcactcagt ttacagctat cctgttgaat
     9961 gagtttccag tagcgcttga tagccttgta ttcatgggat tttcgatgaa actgattcat
    10021 gatttggaca tgcacacgac tcatagcacg gctaagatgt tgtacaatgt gaaagcgatc
    10081 aagaacgatt ttagcacacg ggaaaagttg tctagctaag tcatagtaag gactaaacat
    10141 atccatagta atgattttga cgcgacatcg gacggctcta tcatatttaa gaaagtgatc
    10201 tcggatgaca gcttgtgttc taccttcaag aacagtgatg atatcgagct tttcaaaatc
    10261 ttgcgcaata aagctcatct ccatctcccg attgaaacag tcactccccg gactgtttca
    10321 acgtcccagg acataatctc aggaagacgc gaaaaatcat gctcaaagtg agaatcattg
    10381 agcttgcgaa tgacagttga agttgaaatg gccagctgat gagcaatatc ggtcatagaa
    10441 atcttctcaa tcaacttttg cgcaattttt tggttgataa tacgaggaat ttgatgattc
    10501 ttcttgacga tagaagtttc agcgaccatc atttttgaac agtgatagca cttgaatcga
    10561 cgctttctaa ggagaattct agtaggcata ccagttgtct caaggtaagg aatcttagac
    10621 ggtttttgaa agtcatattt cttcatttga cttccgcact cagggcaaga tggggcgtcg
    10681 tagtccagtt tggcgatgat ttccttgtgt gtatccttat tgatgatgtc taaaatctgg
    10741 atattagggt ctttaatgtc tagtaatttt gtgataaaat gtaattgttc catatgattc
    10801 tttctaatga gttgttttgt cgcttttcat tataggtcat atgggacttt ttttctacac
    10861 aaaaataggc tccataatat ccatagggga tttacccact acaaatatta tagagccata
    10921 aaagcatcaa catcttgtgt ggcacgtaaa ccatgatatt ctaagacata accaccgaca
    10981 cagataattg ttaaagtcag attttcctga attaattcct tatttagggc ttggaagacc
    11041 ggtttcattt tatccatgtt tgtatttctc catcaatttt tgaacattgg ttaacttagc
    11101 aggtttattt aatgaaatca catatttatg agttggagta tgctcttgaa aggcatactt
    11161 caagctaatt ttttgaaaac gggttagttc tttggagtct agcaactttt ctacatcttg
    11221 gtttgttaaa taagaatagt cttcaaaaat aacttttcgc aaatagcgaa accaatggct
    11281 tgcgttgaat tgtgattgtt tggatgcctg tatcatataa tcgtaccaat ccattgtctt
    11341 cctcctataa aatttagttt atattattgt agtttatatt caaaaatgta gtttttctta
    11401 attagctcgt atctatagga tgatactgaa aatcttcttg ttgctttaaa tcacaatcga
    11461 aaaattctgt ttttcatctt agaaaagaat gtttagaaat gtaaaatgaa ccttttttct
    11521 tatccgaaaa ccttactaaa gtatataatt taggaagtca atcctgtatg ataatgtttg
    11581 tactatcgtc gagtttttgc ttgattgcct aacgagataa attttagaag aattttcggt
    11641 gtgatttgac aagcttctga ctggaaggat agttacacta gtattgttta ttaaaatgag
    11701 cagatagaga aaatttggaa tctatttgct tattatcaat cgttttttta gcttatttgt
    11761 cttagattgg tatagaactg agctatggat taatactctt gtatcttatc ctgttcctaa
    11821 atatgttggt agaaaaatga agcagttgtt acgagtgtct gtattggaaa aaattttgtc
    11881 tatagaattc tttaaatgat atgaaggcta ggaatgccaa agcactgaca tatttcgttt
    11941 gaatctcatc cgctctcttt acttgtattt gtagaaatgc tatcagtaat atattcgcga
    12001 acactatgat ttacaacagt gtggtcgtac atctttgtaa ctttattata caacaaccat
    12061 ttacaggtgt aaagttgagc agtatcttta gtaaatttag ggatttgttt tgtcatagtt
    12121 ttgatacctg tattcgttgt ttcatgagca tttgacgttt cttttcatgt aggcatttca
    12181 acaattagaa tgatattttt ccgaggatga acttatatat tgtgactttt tagagttatg
    12241 atgcctcttg atttgactat cgctatcaat ttcatccact tttacagttt catggtttta
    12301 tgaaccgaaa catctaggta caggttttag catcaattga ttgtttttga gccatatgaa
    12361 gttgaaacgt ggagatgctt ttcttgtgat aacgccctat tcaaagagga ataaccgttt
    12421 ttggagagag ttcagtacta tgtggcgcta aatactatat gtaaaacata tattaaacaa
    12481 gatttaacta aggagaattg taaaaacaaa aatgagaatt tcatataaag tttattctag
    12541 gagtatgtat cttgaataaa aattgttatt taagttctgg gggttatgat gaatgttttt
    12601 ataataataa aatgcagcta gaagaaaagt tattttaata taaatcactc aacatagcga
    12661 gaaggcggtt tcctatatgg aagtcgtctt gttttcatat tgtctaaata cgagatatct
    12721 actacaggtt atagttgatt taaacaggtc tatagatttc taatatatta aggtgaaata
    12781 atatcttgta atacattgct atgttctatg aaaaaagcga cgatagctaa tgcacaagct
    12841 cctatacttc cacgatgttt gttgtaaggt aaaatttcaa tttctatatt acgagtaaag
    12901 ggaacgaagt ggagctggtc ttggatttta tccctgactt catgagtgaa aggttgataa
    12961 ttaagcaatt gactgttgat atagatttta tcagcaggat tgatgaggag gagatttgca
    13021 atagaagtgg ctaataaatt gactccttta tcaatttgtt gacgtaaagc ggagtcgcct
    13081 aaattataag ccgttaaaag ggtgtctaaa tgaatgtctt tttcagtctt tacaaggctt
    13141 tttagtacag ttagttggga atttttaaat aataattggg cgtgtttgat taaccaagca
    13201 tccgaaatat atgtttgtaa acaacctttt tttccgcatt cacaatattg cccattcaat
    13261 tcgacaatgg tgtgtccaat ttctccgata taaggatttt tagaggctcc tattttttct
    13321 tttgtgaaaa aggaagtgta aatacctaat ccagcgtgta ggaaaataaa gttatcgggg
    13381 gtattgtgtg gattaaaaag gtattgtcct atagccatac aatcgatatt attttttaca
    13441 ataaaaggaa aattgaatct tttaattaca tttaataaat taaaagattc ccatatgggg
    13501 ttgtttgtaa tgatacttcc ggagtctttg taataatgtc caggtattga taagccaaat
    13561 ccaagtaatt ttgtttccaa agggacgtac tctatagctg tttttatcat attggtaatg
    13621 gtggaattga tttctgaaat aggataatct tcattcaaaa tttctgtctc gaaaagagtt
    13681 ttcccttgta agtcacatag actgagaaag atacctagga cgtttatttc aatacctcca
    13741 acaacatacg gaatattatc tgtgatagaa atagtttttc tacgtcttcc agatccggaa
    13801 aactcgctaa attcatcacc agtttcgtat atgagggact gttcgcttag ttcttttatg
    13861 atgttagtcg ttgttgctgg agtaagtcct gtttcattaa caatatctgt acgggatgtt
    13921 gctggatttc gatatagaaa ctccagtata gtggctctat tttgtaaaaa ggctgattgt
    13981 tttgtaatca tttgtttcct cctttggttt attttatatt aaacataaga aaaaatcaat
    14041 taaaattatt attctataca aagaaaaaaa tattgtaaaa acaacaaaaa atatattgac
    14101 aacgctttct gttagtggta tatttaattt ataaaaaata aaaaaaggag ttccggtgat
    14161 gaacaatatt ttagcgtttt tagaaacaaa agtcgctccg tttggtgaaa aagttggcaa
    14221 ccaacggcat ttgaaagcta ttcgtgaagg atttatgatg gcaatgcctt tgattttagt
    14281 cggctcttta tttcttattc taatcagttg gcctcaagag gcttttacaa attggctgaa
    14341 tagtgttgga ttgctaagta tcttgacaac tatgaatcag tcaacagtag cgattatctc
    14401 cttggtcgct tgtttcggta ttgcctacag gttgtcggaa ggatatggta cagatggtcc
    14461 gtcggcaggg atcatagcct tatccagttt tgtattgatg gcacctcgtt tttcgagtat
    14521 ggtttatgat aaaaatgggg agcaggtcaa gcagttattt ggcggcgcaa taccattttc
    14581 tagcctgaat gcatcttctt tgtttatggc gattactatt ggattggtta cagcagagat
    14641 ttatcgtatg tttatccagc gcggaattac gataaaaatg ccaagtggtg tcccagatgt
    14701 agtaagtaaa tcattttcag ctcttttacc tggttttact acttttgttt tgtgggcttt
    14761 ggtcttaaaa ggtcttgaag cggcaggagt tgcaggaggt ctcaacggac tcctaggtgc
    14821 aattgttgga acaccgctta agttaattgc aggaacgctt ccaggtatga ttctatgtgt
    14881 tattgtaaac tcattctttt ggttctgtgg agttaatggg ggacaagttt taaatgcttt
    14941 tgtagaccca gtttggttac aatttactac agaaaaccaa gaagctgtgg ctgcaggaca
    15001 aacactccaa cacattatta cattaccgtt taaagattta tttgtattta ttggtggcgg
    15061 tggagcgact attggtcttg cgatttgtct cttcctattt agtaagagtc gtgcgaataa
    15121 aacattaggt aagctagcta ttataccgtc tatttttaat atcaatacag ctattctatt
    15181 tacgtttcca acagttttaa atccgattat gctgattccg tttattgcta ctcctacaat
    15241 caatgccttg attacctatg tatcaatggc tgtaggatta gtaccctata caacaggtgt
    15301 aatccttccg tggacaatgc caccgattat aggaggcttc cttgcaacag gggctagttg
    15361 gcgaggagct ctattacaag ttgttttgat tttggtttct gtagcaattt attatccatt
    15421 cttcaaaatt gcagataaac gcaatcttga aaaagaaaaa gctactgttg gagggaaata
    15481 agatggttat cagagtattt gatcaacaga aaaatactta ttctagcttt gccttagagg
    15541 aattaagtta ctatatgaat cgggtcttta agactaacat agagcttgtc gaggagaagg
    15601 aagcggatat ttttgtagga ttagtcaata aagaggacag aaaagaccat gttcttatct
    15661 cattagacaa gggtaagggg agaattgagt ctaatacaat tgtaggttta cttattggaa
    15721 tttaccgaat gtttcatgaa tttggggttg tgtacactag accagggcgc agacatgact
    15781 ttgttccaga gttacgattt gaagattttt tagataaaga gctatctata gatgaaacag
    15841 ccagttacta tcatagggga gtatgtatag agggagcgga ttcatttgaa aatatactag
    15901 atttcattga ttggctacct aagattggga tgaacagttt tttcatccag tttgaaaatc
    15961 cttactcttt tttgaaacgt tggtatgaac atgagtttaa tccataccta aataaagaaa
    16021 aattctcaaa tgaattagta caagaattga gtgataggtt ggataaagaa ttgcaaaaaa
    16081 gaggtcttat tcatcatcgt gttggtcatg gatggacagg tgaggtttta ggttactctt
    16141 caaaatttgg ctgggaatca ggtcttagta tttcagagga gaagaaaccg tatgtcgctg
    16201 aaataaacgg gaaacgagaa ttatttaata cggctccgat tttaaccagt ctggattttt
    16261 caaatccaga tgtggcggat aagatggtag aaattatcaa ggattatgcc aagaaaagac
    16321 ctgatgttaa ctacttacat gtatggttgt cggatgctcg taataatatt tgtgaatgcg
    16381 aaaactgtag acaagaattg gtttcggatc agtatattcg tattctcaat caattggata
    16441 gggctttaac gagtgaggga ttagatacaa agatttgttt tctgctttac catgagttgc
    16501 tatgggcgcc tcagaaagaa aaattagata atcctgaacg ctttaccatg atgtttgcac
    16561 cgattacaag aacatttgaa atgagttatg cagatgtaga ttttgacaat tccataccta
    16621 cgcctaaacc ttatctgcgt aataaaatta tacttccgaa ttctcttgag gaaaatttat
    16681 cttatctttt tgagtggcaa aaaacattta aaggagatag tttcgtatat gactatcctt
    16741 tagggcgtgc tcattatggc gatttaggct atatgaaaat tagtcaaacc atttacagag
    16801 atgtatctta tctttctaac ctacatttga acggttacat ttcgtgtcaa gaattacgtg
    16861 ccggattccc tcataatttt cctaattatg ttatggggga aatgctctgg aagaagacaa
    16921 gaagttatga agaattgatt gaagaatact tttctgcttt gtatggggaa aattggcagt
    16981 ctgttgttga atatttagaa aaattatcca gttattcctc atgtgattat tttaatgcaa
    17041 ttggcagtcg tcaaaatgat gttttagcga atcattatta tatagcttac aatctagctg
    17101 ataatttttt gccaattatt gaggaaaata tttctaagtt attaaatagt caaaaggatg
    17161 aatggaaaca gctcagttat catcgtgaat atgttgttaa gatggcgaag gctttatatc
    17221 ttcaagcaac cggaaaaaca aggcaagctc aagatgaatg gagaaatgtg ttgaattata
    17281 tccgtgggca cgaactgcta ttccaatcta atttggatgt ttatcgtgta attgaagtag
    17341 caaaaaatta cgctggtttc cacttataaa tcataagtat agaaaatgaa ccaaggtatt
    17401 cagagaagat tgatcctaaa tattatgaaa tttaaggatt tttaagatat ttagggtcga
    17461 ctttctattt gtatcgtagc gaagtcattt taataatgat gtgtaaaaga tggatcaaga
    17521 ttgaggagga agaaagatga aatcaaaaga agaaataaat atgcttggtt ttacaattgt
    17581 cgcttacgca ggagatgcaa ggtcagattt gatggatgct ttggcgtttg cgagagatgg
    17641 atattttgaa caggcaagag aattggttga gtctgcaaac gactcaatag tgtctgccca
    17701 tcgagaacag actaatttat tagcggagga ggcatctgga gataattttg aagtgagttt
    17761 tatcatgatt catggtcaag atactttgat gacaacgatg ctattgtatg atcaggtcaa
    17821 gttttttatt gatgaatatg aacgaattcg aaagattgaa gaacatattg gtttgcaatg
    17881 aggattagtc atggaaaatt tacagtttaa agccttaccg aaggagtttt tattaggagc
    17941 tgctaccgct gcttatcaag tagagggtgc aactagggta gatggtaaag gaataaatat
    18001 gtgggatgtt tatttgcaag aaaatagtcc gttcttacca gatccagcta gtgattttta
    18061 ttatcgttac gaagaggata tagctttggc ggcagaacat ggtttgcagg ctttgcgttt
    18121 atctatttct tgggttcgta tatttcctga tatagatgga gatgctaata tattggctgt
    18181 tcgttattac catagagtct ttcagtcttg cttaaaacat aatgtgattc cgtttgtttc
    18241 tttacatcat tttgattcgc ctcagaaaat gttagaaaca ggggattggt tggatagaga
    18301 gaatattgat catttcatac gatatgctcg cttttgtttc caagaattta cagaagtcaa
    18361 gcattggttt acaatcaatg aactgatgtc tcttgctgca ggtcaatata taggaggtca
    18421 gtttcctcca aatcatcatt ttcaattatc tgaagcaatt caagcgaatc ataatatgtt
    18481 gttggcgcat gctcttgcag tcctcgaatt tcatcaatta ggaattgagg gagagatagg
    18541 ttgtattcat gctttaaagc caggctatcc tattgatggg caaaaagaaa atattttggc
    18601 agctaaacgg tatgatgttt ataataataa atttctatta gatggaactt ttttgggcta
    18661 ctacagtgag gacacgcttt ttcacttgaa tcaaatattg gaagctaata attctagctt
    18721 tattattgaa gatggtgatt tagaaattat gaagagagct gcacctctta atacgatgtt
    18781 tgggatgaat tattatcgtt cagaatttat tcgtgaatac aaaggtgaaa atagacaaga
    18841 atttaattca acaggaataa aaggacagtc ttcttttaaa ttaaatgctc taggtgaatt
    18901 tgtaaaaaaa actggtattc cgacaacaga ttgggattgg aatatttatc ctcaagggtt
    18961 atttgatatg ttgcttcgta tcaaagaaga atatcctcaa catccggtca tttatttaac
    19021 tgaaaatggt acagccctta aagaagttaa gccagagggc gagaatgata ttattgatga
    19081 cagtaagaga atccgttata ttgagcaaca tttacacaaa gttttagagg ctcgagatag
    19141 aggagtcaat attcaaggct attttatatg gtctttgcaa gatcaatttt cttgggcgaa
    19201 tggctacaat aagcgatatg gtcttttctt tgttgattat gaaacacaga agagatatat
    19261 taagaaaagt gctctttggg taaaagggct aaaacggaat taaggttagc gatttgactg
    19321 atgtttaata tgttttaaat atgaggttga attttttata ggaggagttt tatggataag
    19381 ctagtcgctg ccattgaaaa gcaacaaggg aaatttgaaa aaatttctac taataactat
    19441 atgatggcta ttaaagatgg attcattgct actatgcctt taattatgtt ttcaagcttt
    19501 ttgatgatta ttattatgat tcctaaaaat ttcggagtag agttaccgag tccagctatt
    19561 gtctggatga gaaaagtgta tatgttaacc atgggagttt tgggtattat tgtttcaggg
    19621 actgttggaa agtcattagt tggaaatgtt aacagaaaaa tgcctcacgg aaaggtaata
    19681 aatgatactt ctgcaatgtt ggcagccata tgtagttatc tggtattaac tgtaacgctt
    19741 gtagttgatg agaagacggg atctacaagt ttgtcgacaa actatttagg atctcaagga
    19801 ttgataactt cgtttgtcag tgcctttatt actgtaaatg tttaccgatt ctgtattaag
    19861 cgagacatta ctattcattt acctaaggaa gttcctgggg ctatatcaca agcttttaga
    19921 gatatttttc ctttttcttt tgttttactt attagtggtt tgttagatat tgtatctcgg
    19981 tttagtttag atgttccttt tgcccaagta tttcaacaac tattgactcc tatttttaag
    20041 ggggcagaat catatcctgc tatgatgttg atttggttta tgtgtgcttt gctttggttt
    20101 gttggaattc atggaccatc tattgtctta cctgctgtta cagctttaca actgagcaat
    20161 atggaagaga atgctcaact tcttgcaaat gggcagttcc cttatcattc tttaacacct
    20221 aatttcggga attatatcgc tgctattgga ggaacggggg ctacctttgt tgtaccattt
    20281 attttgattt tctttatgcg gtctaaacaa ttaaaatcgg taggtaaagc tacaattact
    20341 cctgttttat ttgcggtaaa tgaacctctt ctatttggta tgcctgttat tttgaatccc
    20401 tatctttttg tccctttttt gatgactcca ccagtaaatg tatttctagg aaaggtattt
    20461 attgatttct ttggaatgaa tggattttat atccagttac cttgggcttt tcctggtccc
    20521 ttgggattgt taattggaac gaattttcaa cctatctcct ttgtgctttt atctttgatg
    20581 ttagttgtcg acatattgat ttatttgcca ttctgtagag cgtatgatag acagttactg
    20641 atgaaagaag atgttgcaag ctcaaatgat attattttag aggaggatac aagtgaaata
    20701 atgcctggtg agatagatgt aataaaaagt aaggagttga aagtactggt tctttgtgca
    20761 gggtctggaa caagtgcgca attagccaat gcaattaacg agggcgctca attagcagaa
    20821 gttagagtga ttgcgaattc aggagcgtac ggagctcatt atgatattat gggtgtttat
    20881 gatttaatta ttctggctcc acaagttcgg agttattata gagagatgaa ggtggatgca
    20941 gaaagattag gtattcagat agttgctacc agaggaatgg aatatattca tttaacaaag
    21001 agtccaagta aatccttaca atttgtattg gagcattacc aagctgtgta gtaagttttt
    21061 ccatctttta tttgagtaag aactttgctt acagacaggc ttggatttaa aaacgttccc
    21121 cctttttaat ataaaaatcc ctctttcaca attgtaaaaa gagggatttt gtattttatc
    21181 tcttagacca agttctcttc ataaagagaa gtaggattgg gtaaatctcc aagcggcctg
    21241 caatcattgc aaaggagagg agaatttttg agataggact aaagattgag aaactagaag
    21301 tggttcctag aataggcccg atattattga aacagctaaa gacagcgctg gtcacgatca
    21361 gaaaatcatt gctatctagg ctgacaataa agataaggga tagcaaaatc atagcataga
    21421 tgacaaagta cttgagaatt ttatgctggg tatccttatc aatcaccgtt ttattcacat
    21481 ggagagtcaa aacacggtgg ggagatagaa tggacaaaat ttgatttttg gcaatttttg
    21541 aaaggatgag gcctcgaata atcttgagtc cacctgcagt tgatccagca gaaccaccga
    21601 ttgtcatgag gaagaggagg ataaactggg agaagagggg ccagttggta atatctccat
    21661 atccaaaacc agttgttgta atgatgttgg aaacctggaa gaaggtcatt tcaaagctct
    21721 ttgaaaaccc tgggtagagg tagagggtgt tgaggctaat caagcctgta gaaaccagta
    21781 caatgaccaa gtaagcccga agttcttcgt caccaaagaa ggccttgatg cgacggagca
    21841 tgaggtagta gtagaggttg aaatttaccc caaaaatcag aactccgata ctgaccagat
    21901 aggtaatcag tgagctgcca tagtgggcaa ttccgtcgtt atagacggta aagcctccag
    21961 ttcccgctgt ccccatagca atgacaaaac tatcgtagag aggcatacca gctagataat
    22021 agatgatgac aaagagggag aagagagcta gataaaggag atagagaatc tgggcagtgt
    22081 tttttagttt ggatacaacc ttgccaaaaa caggacctgg aacctcagcc ttcatcacct
    22141 ctaggtggct atttttggca ttgtccataa tagcaagtgc aaaaacaagc actcccatcc
    22201 ctccaatcaa gtgggtaaaa cttcgccaga agaggaggga acggctgaga accgaaacgt
    22261 cgttcaaaat acttgctcca gtagttgtaa acccagaact aatttcaaaa aaggcatcaa
    22321 taacgctagg gatttgccca gaaaagacaa aggggagacc accaaagaaa gaccaaagga
    22381 tccaacagag ggcaacgatc aagactccct ccttggcata aatccgttga ttttttggct
    22441 tctgtaaact ccctgaaccg cctaacaata cgagaatccc tatggtcgaa aagagggccg
    22501 taaagacttg gctcgattca cggtaataga cagcgatagc cacaggaacc aagaggagaa
    22561 cagcttcaat caaaagtaac tttgaaagga ggtaacgaat catactttta ttcatttttt
    22621 acctcgcaat caagtcataa atcttggtga tgtttggcaa caaggttgtt actaggagct
    22681 tgtctccaac ttccaacata tcctccccag ttgggaaaat agtcttgccc tttcgaataa
    22741 tggctgcaat aagaacccct tttttcaatt tcagttgaga aagaggtttg gcagtcattt
    22801 tattggcttc cttgatatgg aattgcaggg tttcgatttg gccattggct agatggtgca
    22861 tggcttgaag gtctgaatac tgggcattaa ctcgaccacg aataaagtgc ataatcgtat
    22921 ctacagcgat gcttttaggt gtgatgatac ttgaaaaatc aggcgcattg ataatctcga
    22981 ggagactggt acgattgacc ttagtaatat ttttctgtac acctaccctg tcaaggaaca
    23041 tagatgtaat cagattttcc tcatcgacac ctgttagagt cgcaacggca tcatagtgtt
    23101 gagcactttc ttccagcagg atatcttttg cggttccatc tccttgaacg atgtagagat
    23161 ttgggaattt ctcgctaaag aagctggcga tttcaggatt gatttcaatg acttttgtat
    23221 cgatacgact atctttgaga ataccaagta gataataggc aattctacct gccccaacga
    23281 tgagaaggct cttcacggcg cgtgatttaa aataattatg gaagagtatc atatcgacac
    23341 ggttaccagt gacaaagatt ctatctttat cctgtacagt catgtcaccg cttggaatga
    23401 taatttgatg ctccctctct atcgcacaga caatgacatt accaaatttt ttacgaaaat
    23461 cagaaatggg catttggcaa agaccgctgg tggacttgac gacaaattcc atgaggctaa
    23521 cgcgtccacc agcaaagcgt tcgacagaca gggcgttggg gaagtcaatg atattcgcga
    23581 tagcgcgggc agccaagagc tcaggattaa cgataagaga aaaaccgaga atattctttt
    23641 ccttgaaata agagttagaa tattcagggt tccgcacccg aacgatagtt tctttagctc
    23701 ccattttctt ggctagaact gctgcaatca tgttgacttc atcgtgctca gtcagggcga
    23761 taaagatatc acaatcttgg acgctggctt gctcaagaat ggcaaaatcg gccccgttac
    23821 caaggatacc aatgatatca aagcgactga caatatgatt gagaacagct tcgtcttgct
    23881 caatcagcaa aacatcatgc ttttctgcaa ccaaggagcg acagagggca aaaccaactt
    23941 ttccccctcc gacaaggata attttcataa taaaacctac tttttcatga tgtaactatc
    24001 ataccctttt tcaagaaaaa atgcacctac tagctaataa ccagagtttt tagtaggaaa
    24061 tttgctataa gttaaaacta taccctaacc aattgaaata gctattagcg actttctctg
    24121 aaatatggta tgataaagga tatacaagga gataaaatga ataataattt actggtatta
    24181 caatcagact ttggtctggt tgatggtgcg gtatcggcta tgattggagt ggctttagaa
    24241 gagtctccaa ccttaaaaat ccatcacttg acgcacgata tcacgcctta taatattttt
    24301 gaggggagct atcgtctctt tcagacggtg gattactggc ctgagggaac gacgtttgta
    24361 tcggttgtcg atccaggtgt cggttcgaaa cgtaagagtg tagttgccaa gactgcaaaa
    24421 aatcaataca ttgtcacgcc agataatggg acgctttcct ttatcaagaa acacgttggc
    24481 attgtagcca ttcgtgagat ttctgaggtg gccaataggc gtcaaaacac agagcattct
    24541 tataccttcc acggtcgtga tgtctatgcc tatactggtg ctaaactggc cagtggtcac
    24601 attacttttg aggaagtagg gccagagctc agtgtggaac agattgtaga gcttccagtc
    24661 gtagcgacca tcatagaaga tcatctggtg aagggagcca ttgatattct ggatgtgcgt
    24721 ttcggttcgc tttggacctc tatcacacgg gaagaatttt acaagctgga accagaattt
    24781 ggtgatcgtt ttgaagtgac catctatcat gctgatatgc tggtctatca aaatcaggtt
    24841 gtctatggca aatcatttgc agatgtgaga attgggcaac ccatccttta catcaactct
    24901 ctctatcgtt taggtttggc tatcaaccaa ggttcctttg ccaaggccta taatgtaggt
    24961 gtcggttcat cttggaccat tgaaataaag aaaatagaag gataaaatag gagaatagta
    25021 tggaaatcaa atttacaatt aaacaagttg ttgctgtcgg aattggcgct gccctctttg
    25081 tcgtcatcgg gatgatcaac attccaaccc ctgttccaaa tacaagcatc cagcttcagt
    25141 atgcggtaca agcgctactt tctattattt ttggaccgat tatcggtttg cttgtcgggt
    25201 tgattggtca tgcaatcaag gactctcttg ttggttatgg tctatggtgg acttggatta
    25261 tcgctagcgg actctttggt ttagttgtgg gactttttag aaagtacgtt cgcgtgatca
    25321 atagtgtttt tgactggaaa gatattctta tttttaatct cattcaacta cttgcaaatg
    25381 cccttgtttg gggtgtcttg gcaccacttg gagatgttgt gatttatcaa gaagcggcag
    25441 aaaaagtatt tgcacaaggg attgttgcgg gaattgccaa tggtgtatct gtagctattg
    25501 caggaactct tctcttactt gcctatgcag gaacccaaac tcgtgcagga agtttgaaaa
    25561 aggactaata ctcaatgaaa atcaaagagc aaactaggaa gttagccgca ggttgctcaa
    25621 aacagtgttt tgaggttgta gatgaaactg acgaagtcag ctcaaaacag tgttttgagg
    25681 ttgtagatga aactgacgaa gtcagtaacc atacctacgg caaggcgaaa ctgacgtggt
    25741 ttgaagagat tttcgaagag tataaaatga tggggaaggc tgggcaacta gtctttttcg
    25801 atgtttatag attagttagg caagtaagct aggataggaa tctttttggc gctaagattt
    25861 taagagaaga gactgcaaga agggcttgat ttatgataaa atagaagtct aagaagcgaa
    25921 tgaagagagt aagatgaaag aagctataat tgagtggaag gatttctctt tccggtatga
    25981 aacacaacaa gaaccgacct tgcaagggat agacttgacc atttacaagg gagagaaagt
    26041 cttaattgtt ggaccatctg gatcaggtaa atctaccttg ggtcagtgtt tgaatgggat
    26101 tattcccaat atttacaagg gtcagacata tggagaattt ttgataaagg gtcaaacagc
    26161 ctttgatatg agcatctatg ataagtctca tctggttagc acagttttgc aggatacaga
    26221 tgggcagttt attggcttgt ctgtggcaga agatttggcg tttgctctgg aaaatgatgt
    26281 gacagcccta gatgagatga aaggtcgtgt ttataaatgg gctgaaaagc tggaccttct
    26341 tcctttactg gatcagcgtc ctcaggattt gtcaggtgga caaaagcagc gagtcagtct
    26401 agctggtgtc ttgattgatg aaagtccgat tctcttgttt gatgagccac tcgccaatct
    26461 agatcccaag tcaggtcagg atattatcga attgattgac cagattcata aggaagaggg
    26521 gacgacgact ctgattatcg agcaccgttt ggaggacgtt ctgcatcgcc ctgtggatcg
    26581 gattatcttg ataaacgatg gtcgtatcct ttttaatggg agccctgacc agttgcttgc
    26641 gactgattta ttgactcaaa atggaattcg agaacccctt tatctaacga ctctccgtca
    26701 attaggtgtg gacttagtca aggaagaaca gttagcgaat ctggataaca tgtctatctc
    26761 aaaaggtcag gttcagctgc agaatgaact ggcaaaagaa actccagaat tgcagtcact
    26821 ctttaaatta gaggacgtgt ctttctctta tgatgataga ccgattttaa aatccctaca
    26881 tttagatatt aaaaagggtg aaaagattgc tattgtcgga aaaaatggag cagggaaatc
    26941 aactctagcc aaggctataa gtagctttat tcagacggaa ggacgctatc tttgggaaaa
    27001 acaggatata aaaggcgatt ctgttgcaga gcgggcggaa cgagtaggct atgtgctaca
    27061 aaatcctaat caaatgattt caaccaatat gatttttgat gaggtggctc tagggctccg
    27121 tttgcgaggt gtggatgaga aggaaattga aacgagagtc tatgaaacct tgaaaatctg
    27181 tggactttat gaattccgta attggcctat ttctgccctg tcatttggtc agaaaaaacg
    27241 tgtcaccatt gcttcaattt tggtcttagg agctgaaatt attctcctag atgaaccgac
    27301 tgcaggtcaa gatcagaaga actatactga gattatggaa tttctcgaag agttacatca
    27361 aaaagggcat accattgtca tgattaccca tgatatgcaa ttgatgctgg attattcaga
    27421 ccgggtcctt gtcatggtgg atggagaatt gattgccgcc gatactgttc cagccagtct
    27481 gttgagcgat cctgagctgt tagtaaaagc caatctaaaa gaaacctcca tctttaactt
    27541 ggctaagaaa ctagatgtgg atccactgga tttaacggca ttttacaaag aaaggagaga
    27601 gggatgcaag ctaaattaat cggttaccag catagagata ctgtgattca tcgcttgtca
    27661 ggagctggga aacttctctt tttcattctg gtatcattgg cggccatgat tagctatgat
    27721 accagaatgc tcttgctgat tgccatcttt tcagtctttc tcctctattt atcagaaatt
    27781 cgctttaaag atgtttcctt tgtagccgtt tttgcgacgg tatttgccgt tttaaacgtt
    27841 ttgatggtct atctcttttc tcccgagtat ggggttggac tttatggaga gagaagtgtg
    27901 atttggcagg gaatcggtgt ctacactcta accagccagg agctctttta tctgctaaat
    27961 ttggccatta agtatctttg caccattcct ctggctatta tctttttgat gacaacccat
    28021 cctagtcagt ttgcttccag tttaaatcaa attggtgtgc cctataagat tgcttattct
    28081 gtcagcctga ccttgcgcta tattccagat ttgcaggaag aattctttac tatcaagatg
    28141 tctcaggagg cgcgtgggat ggaattatcc aagaaagctt ctcttatgca acgaatcaaa
    28201 ggcaatctgc tcattattac gcccttgatt tttagctcgc tagaacgcat tgataccatt
    28261 gcgactgcca tggagcttcg ccgctttggg aaagagaaaa aacgcacatg gtatagttat
    28321 cagaccttga aaaaaggaga ctatattacc ttgctcttgg caaccttgtt tttagtagct
    28381 agtttactac ttatcttgca gaatcaggga cgattttaca acccttggaa atagcttgaa
    28441 aaaattgaaa aaatcaagtc gtttctattg acaatgattc tgaaagtgtt atactaagaa
    28501 agtagtttcg ctgatttact tcaaacctgt tgtgaggtaa gttaacgatg ccttaaccac
    28561 gctgtctgct gagcttgact ccgggcagtg tggctatttt tttgcaatgg tgaaaggaag
    28621 caagtcatga caaatcacat tgtattattt gaacctcaaa ttccacaaaa tacgggcaat
    28681 atcgcgcgta cttgcgctgc gaccaattct cccctccaca tcatcaagcc tatgggcttt
    28741 cctattgatg accgcaagat gaagcgggct ggattggatt actgggataa gctagagatt
    28801 tatttttacg agagtttgga agatttcata tctcagatga agggaaaact ctatctgatt
    28861 tcgaaattcg cggaaaaagt ctattctgag gtggatttat cgactgacga ggaccattat
    28921 tttctttttg gacgtgaaga caagggctta cctgaagatt ttatgcgaga acatcctgag
    28981 aaggctctcc gtattcccat gaatgatgaa catgtccgca gtctcaatgt gtctaatacc
    29041 gtctgcatga ttgtctatga ggctcttcgc cagcagaact ttgcaggtct tgagctcgtc
    29101 catacctatg aagtggataa attgaaataa aaaatgaaaa tgaacaaaat gcttgcgctt
    29161 gcaagcgttt tttgttatga taaaagagtc ttcagggcag ggtgtgattc ccgaccggcg
    29221 gtgactttaa ctaggaaatg atcttttcct tttatacttt gttgacaagc tttgcctaac
    29281 cagaagttat gcctacagct tgtcgcctag tctaaaagaa aaatctctat ttccttctct
    29341 ttaaagaagt ccgcgagcgc aagctgatgt ggtgagattc cacaaccgac agtatagtct
    29401 ggatgggaga agacgaaaga atagctttgt ctgttttgat agatttatag ccggattgta
    29461 accacttgct ttgtttttct ttaatagagt aagagggaac ttttgggata taaaaagtga
    29521 gaatagatag aggaatcctt tccaacttct tctgatttta tagaaaattg gaggaacctg
    29581 ttatgacaaa cacacgtcga ctttcgacca ttgcaattct atcagccatc tcatttgtgc
    29641 tgatgtactt tgactttccg cttttaccag cggcatcttt cctcaagatc gaatttagta
    29701 tcttgccagt ccttgtgggt ctggtggtca tggatttgcc tgctgctcta ggagtgctct
    29761 tgcttcgctc actcttgaaa ttgcttctta acagccaagg agtgaatact tacattggtt
    29821 tgccgatgaa tatcgtagct ttgggagttt ttgtcatcgt atttgctttg atttggaaaa
    29881 aggaacggac aacccttcgt ttcctactag gctctctagc tggaactatt ggtttaacct
    29941 tggccatgtt ggttctcaac tatgtttatg ctgttccttt gtacgctaag tttgctaact
    30001 ttgatattgg aaaaattttg ggattttcca actacctaat gaccatggta ttacctttta
    30061 acttgattga gggtgtaatc ttttccgttt cattctggtt gttgtacgtc cttttgaaac
    30121 caaccttaaa acactatgaa agataaacaa acatttttaa tgaagggcag ttttgccctt
    30181 ttacttttcg ttattcttgg ctatatggtc aaattttacc ctgaaatgtt ggtcaatttt
    30241 gaccaatcga ttcagactgc cattcgagga gacttaccag attatttgac tattcttttt
    30301 cgagccctca cacgtctgat tgatatccca gtgattatca cttgggttgt cattacagct
    30361 tttgtctttt atcgtaagcg atggaagata gaaagtttct tcatgctggg aaatctggct
    30421 ttggcaggtc ttttaatcgt gacctttaaa aatatctacc agcgcccacg accagctatc
    30481 ttacatctgg tggaagagaa gggattttcc ttcccaagtg ggcattctct agctgtaacg
    30541 ctgatggtag ggactttgat tgttattctt agtcagcgga ttaaagatca ggtctggaga
    30601 aaaatcgtac aaatcgtcct tggcctctac ctagtcagtg tgctggtatc aagagtctat
    30661 ctgggagttc attacccatc agacgtcctt gccagtctct gtgtgggctt gggagtcctg
    30721 tttatcgagt ttccctttta tgacaagctc cgcttccaat ggcgatttaa aggcaaacag
    30781 aagtgagtat cgaattccct tgagagaaag aaatgaaagt caatatagca gatcttcatc
    30841 cgactcaact atatttatca gaaaagaagt tgcaagatat tcagatgctt taccagtcgg
    30901 cagaaacaat ccaagtcgat ccaatcagta ttcttgcctt tggagattgt ttgctgatta
    30961 cagatgggca tcacagggct tatcaggctt tattggcagg tcgggatacg atttctgctg
    31021 agtgggatag agatggtggt gatgaactat atcatttcta tgcgcaagct tgcgaggaaa
    31081 gaaagattta ctctgttttt gatttagaag atcgtatcct agctcaagat gggtatgaag
    31141 caaaatggta taactggtgt gatggtttta atcaagcagc aactcttttg ttgaaaaggt
    31201 agtgcattgt gttttgttcc ttattataag gtcaatcatt gtgaggaagc ttttgcttgg
    31261 tatcaggatg tgaacttggt ttacctcgta gatggggtga agcttcctta cagtcaagcg
    31321 accttggaag ccatgtattc ctatttggat cggcatggtg agcttttttg gattgaagtc
    31381 aaggagaagg gagaatggtt tccaattggg gatattacac tatctcagga taatctcccc
    31441 attgtgattg ggaattccgc ttaccaacat cgaggacttg gaaaaagatt ctaagtgctt
    31501 tgattgaatt ggctcgagta aaaggatgga aagaattgag agtcaaggaa atctacacct
    31561 acaatcatgc ttctaggagg tgtttcaagt cgcttggatt tgtggaaaat ggagcaacag
    31621 aaaaaggaag gggttttata ttggaattag tctaatcctg ccactttctc ccccttaacc
    31681 tttgactatt ccgcaaaatt atcgtaaaat aaagagtaaa tgataaaatg aggtcagagt
    31741 ctgttcgctc tgacgatagt agtataaatg aggagaaacg ctttggaatt agaagtattt
    31801 gctgggcaag aaaaaagtga actatctatg attgaggtag cgcgtgctat cttagaactt
    31861 cgtggtcgcg atcatgagat gcattttagc gatcttgtaa acgaaattca aaactacctt
    31921 ggaacatcaa acagcgatat ccgcgaagct ttgcctttgt tctacacaga gttgaacttt
    31981 gacggtagct tcatctcact tggggacaac aaatggggtc ttcgttcatg gtatggtgtg
    32041 gacgaaatcg acgaagaaat catcgctctt gaagaaaatg acgacgatga agtagcacca
    32101 aaagctaaga aaaaacgtgt caatgccttt atggatggtg attcagatgc cattgactac
    32161 aatgcagatg atccagaaga cgaagatgca tacgaagcag atccagctct ttcatacgat
    32221 gatgaaaatc cagatgatga aaaaaatgaa gtggaagctt atgatgcaga aatcaacgaa
    32281 atcgctccag atgacttggg agaagatgtg gatctcaacg aagacgacga cgagttttca
    32341 gatgacgacg ctgaaaccag cgaggaataa gagttagcta ttgacaatta tcctattttt
    32401 aggtatcata ttgtttgggc acctctttta gaggtcgggg ctccctagtt cttagggagc
    32461 tatttttgtt ttttcaagaa gttatcttct tgtattttat actcaatgaa aatcaaagag
    32521 caagctagga aactagccgt aggctgctca aaacactgtt ttgaggttgt agataagact
    32581 gacaaagtca ggaacacata tctacggcaa ggcgacgttg acgcggtttg aagagatttt
    32641 cgaagagtat tagttgtgaa tctggtgcag tcgtcccaga ttattcttat tagtagggtc
    32701 ttgttttcta tatcccctcg tagttaacaa gaccttgagc attttagaaa gaggaatcta
    32761 tgtctacgaa atatattttt gtaactggtg gtgtggtatc gtctattggg aaagggattg
    32821 tggcagcgag tctaggccgt ctcttgaaaa atcgtggtct caaagtaacc attcaaaagt
    32881 ttgaccctta tatcaatatt gatccgggaa ccatgagtcc ttaccagcac ggggaagttt
    32941 ttgtgacaga tgacggagct gagacagatt tggacttggg tcactatgaa cgtttcatcg
    33001 atatcaatct caacaaatat tccaacgtga caactgggaa aatttacagt gaagttcttc
    33061 gtaaagaacg ccgtggagaa taccttgggg caactgttca agtcattcct catatcacag
    33121 atgctttgaa agaaaaaatc aagcgtgccg ctctaacgac cgactctgat gtcattatca
    33181 cagaggttgg tggaacagta ggagatatcg agtccttgcc attcctagag gctcttcgtc
    33241 agatgaaggc agatgtgggt gcggataatg tcatgtatat ccatacaacc ttgcttcctt
    33301 acctcaaggc tgctggtgaa atgaaaacca aaccaaccca acactctgtc aaagaattgc
    33361 gtggcttggg aatccaacca aatatgttgg ttattcgtac agaagagcca gctggtcaag
    33421 gaattaaaaa taaactggcc cagttctgtg atgtggcacc agaagccgtt atcgaatcgt
    33481 tggatgttga acacctttac caaattccac tgaacttgca ggcacaaggg atggaccaaa
    33541 ttgtttgtga tcatttgaaa ttagacgcac cagcagcgga tatgacagaa tggtcagcca
    33601 tggtggacaa ggtcatgaac ctcaagaaac aagttaagat ttcccttgtt ggtaagtatg
    33661 tggagttgca agatgcctat atctcagtgg tcgaagcttt gaaacactct ggctatgtca
    33721 atgatgcaga agttaaaatc aattgggtca atgccaatga tgtgacagca gagaatgtag
    33781 cagaactctt gtctgatgca gacgggatca tcgtaccagg tggttttggt caacgtggta
    33841 cagaagggaa aatccaagcc atccgctatg cgcgtgaaaa tgatgttcca atgttgggag
    33901 tctgcttggg aatgcagttg acatgtatcg agtttgctcg tcacgtttta ggtcttgaag
    33961 gtgccaattc tgcagagctt gcaccagaaa caaaataccc tatcattgat atcatgcgtg
    34021 atcagattga tattgaggat atgggtggaa cccttcgttt aggactttat ccgtctaagt
    34081 tgaaacgtgg ctctaaggct gctgctgctt atcacaatca agaagtggtg caacgccgtc
    34141 accgtcaccg ttatgagttt aataatgcct tccgtgagca gtttgaggca gcaggctttg
    34201 tcttttcagg agtttctcca gacaatcgtt tggtagaaat cgtggaaatt cctgaaaata
    34261 aattctttgt agcttgtcag tatcaccctg aactgtcaag ccgtccaaac cgaccagaag
    34321 aactctacat tgcctttgtt actgcagcgg ttgagaacag caattagcaa aatcagaacc
    34381 tttgagaaaa atctcagagg ttttttgcac acgatgatat tgcagtatat ctgaggtagg
    34441 agtcctctgt atgtacctgc taccgttgaa atcaatagcg actccctctt gtcctgtgct
    34501 agtgaatgga tttatcagta tattgaaatg aaataaaatc tgaacaaatt aattcggaaa
    34561 gccaaatcaa tttctagcaa agttttagga actggattgt atagtgaatt gaaataagat
    34621 gtgaacatct ctatcaggaa ag
//
LOCUS       DAVLIK010000019        34618 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLIK010000019 DAVLIK010000000
VERSION     DAVLIK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34618
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.019"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            576..1028
                     /locus_tag="VXE87_001032"
     CDS             576..1028
                     /locus_tag="VXE87_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0842590.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGDFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1047..2384
                     /locus_tag="VXE87_001033"
     CDS             1047..2384
                     /locus_tag="VXE87_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0842591.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2463..3347
                     /locus_tag="VXE87_001034"
     CDS             2463..3347
                     /locus_tag="VXE87_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0842592.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3347..4180
                     /locus_tag="VXE87_001035"
     CDS             3347..4180
                     /locus_tag="VXE87_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0842593.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4198..6291
                     /gene="nanB"
                     /locus_tag="VXE87_001036"
     CDS             4198..6291
                     /gene="nanB"
                     /locus_tag="VXE87_001036"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0842594.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6303..7406
                     /locus_tag="VXE87_001037"
     CDS             6303..7406
                     /locus_tag="VXE87_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0842595.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7580..8278
                     /locus_tag="VXE87_001038"
     CDS             7580..8278
                     /locus_tag="VXE87_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0842596.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8297..9814
                     /locus_tag="VXE87_001039"
     CDS             8297..9814
                     /locus_tag="VXE87_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0842597.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9939..11267
                     /locus_tag="VXE87_001040"
     CDS             9939..11267
                     /locus_tag="VXE87_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0842598.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11519..12385
                     /locus_tag="VXE87_001041"
     CDS             11519..12385
                     /locus_tag="VXE87_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0842599.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAIMIAIVSF
                     VQFKVLGNDVEY"
     gene            12401..13240
                     /locus_tag="VXE87_001042"
     CDS             12401..13240
                     /locus_tag="VXE87_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0842600.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13512..13964
                     /locus_tag="VXE87_001043"
     CDS             13512..13964
                     /locus_tag="VXE87_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0842601.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNRFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14061..14405
                     /locus_tag="VXE87_001044"
     CDS             14061..14405
                     /locus_tag="VXE87_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842602.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVTALIGRYIKLGTY
                     AVKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14692..15336
                     /locus_tag="VXE87_001045"
     CDS             14692..15336
                     /locus_tag="VXE87_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0842603.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15505..16422
                     /locus_tag="VXE87_001046"
     CDS             15505..16422
                     /locus_tag="VXE87_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0842604.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16440..17324
                     /locus_tag="VXE87_001047"
     CDS             16440..17324
                     /locus_tag="VXE87_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0842605.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKFCMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAKH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17340..18191)
                     /locus_tag="VXE87_001048"
     CDS             complement(17340..18191)
                     /locus_tag="VXE87_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0842606.1"
                     /translation="MDKPDIATVIDSHFEEMTDLEQEIARYFLQAETIQDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHEAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEVQLERIAQLIEDAERVYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFSSVPNKDSQAYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18385..20442
                     /gene="pbp2b"
                     /locus_tag="VXE87_001049"
     CDS             18385..20442
                     /gene="pbp2b"
                     /locus_tag="VXE87_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0842607.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKVTTSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKEIA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVPTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIVTDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAESYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELGNGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQPIVFQGSAPIYSWYKLAYGSFPITAVEALEYSSN
                     AYMVQTALGIMGQTYQPNMFVGTSNLETAMGKLRATFGEYGLGAATGIDLPDESTGFV
                     PKEYSFANYITNSFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20453..21049
                     /gene="recR"
                     /locus_tag="VXE87_001050"
     CDS             20453..21049
                     /gene="recR"
                     /locus_tag="VXE87_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0842608.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21225..22268
                     /locus_tag="VXE87_001051"
     CDS             21225..22268
                     /locus_tag="VXE87_001051"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0842609.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22352..23725
                     /locus_tag="VXE87_001052"
     CDS             22352..23725
                     /locus_tag="VXE87_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0842610.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            23712..24323
                     /locus_tag="VXE87_001053"
     CDS             23712..24323
                     /locus_tag="VXE87_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0842611.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24414..25118
                     /locus_tag="VXE87_001054"
     CDS             24414..25118
                     /locus_tag="VXE87_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0842612.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25337..26710
                     /gene="ftsA"
                     /locus_tag="VXE87_001055"
     CDS             25337..26710
                     /gene="ftsA"
                     /locus_tag="VXE87_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0842613.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26727..27986
                     /gene="ftsZ"
                     /locus_tag="VXE87_001056"
     CDS             26727..27986
                     /gene="ftsZ"
                     /locus_tag="VXE87_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0842614.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27991..28662
                     /locus_tag="VXE87_001057"
     CDS             27991..28662
                     /locus_tag="VXE87_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0842615.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28672..29211
                     /locus_tag="VXE87_001058"
     CDS             28672..29211
                     /locus_tag="VXE87_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0842616.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29211..29474
                     /locus_tag="VXE87_001059"
     CDS             29211..29474
                     /locus_tag="VXE87_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0842617.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29471..30256
                     /locus_tag="VXE87_001060"
     CDS             29471..30256
                     /locus_tag="VXE87_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0842618.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30265..31053
                     /gene="divIVA"
                     /locus_tag="VXE87_001061"
     CDS             30265..31053
                     /gene="divIVA"
                     /locus_tag="VXE87_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0842619.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31401..34193
                     /locus_tag="VXE87_001062"
     CDS             31401..34193
                     /locus_tag="VXE87_001062"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0842620.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
BASE COUNT        10663 a         6097 c         7534 g        10324 t
ORIGIN      
        1 tctaattgaa aacggtaaca aaactaattt agagaatgaa atatagagta tttctctctt
       61 aaaagttttt ggtgaaacga gatgtagaaa ggagatttag ccaaagagtc tattagtgct
      121 agaataatag attagaatta ttttagaaaa acgaagtgag cagcttataa attcaagtcc
      181 ccaaatagat tcatactagt atcttttgca aaaaataaag ggcgacttcc ttcatgaata
      241 tcaatttcat ctataaggaa ggtagctaat tgaactaact tatttattct gtttgtcgct
      301 agaaaaatca gacctccttg tgaagattga ggagatactt aatgaaaatc aaagaagaaa
      361 ctagcaagct agtagcagat tgcccaaaac accgctttga ggttgtagat aagactgacg
      421 tatataatcc aaggtgaagc gactgtggtt tgaagagatt ttcaaagagt atagactaga
      481 gagtagtgtt tttatgtcct tctagtagaa aatgctagac agaagaatgg ggaacttgga
      541 taggaaaaat agattgagaa aggaggttag aagagatgat tattacaaaa attagccgtt
      601 taggaactta tgtgggagta aatccacatt ttgcaacatt aatagatttt ctagaaaaaa
      661 caggactaga aaatttaaca gaaggttcga ttgctatcga tggtaatcga ttgtttggga
      721 attgctttac ttatctagca gatggtcaag caggggattt ctttgaaaca caccaaaaat
      781 atttggatat tcatttagtt ttggaaaacg aagaagccat ggctgttaca tcgccggaaa
      841 atgtaagcgt tacccaagaa tatgatgaag agaaagatat tgaattatac acagggaaag
      901 tggaacagtt ggttcatttg agagctggtg aatgcctcat cacttttcca gaagatttac
      961 atcaacccaa ggttcgtata aatgatgaac ctgtgaaaaa agttgtcttt aaagttgcga
     1021 tttcttaatg tagaaagaga agaacgatga aaaaaatgag aaagttttta tgtctagctg
     1081 gaattgcgct agcggctgtt gccttggtag cttgttcagg aaaaaaagaa gctacaacta
     1141 gtactgaacc accaacagaa ttatctggtg agattacaat gtggcactcc tttactcaag
     1201 gaccccgttt agaaagtatt caaaaatcag cagatgcttt catgcaaaag catccaaaaa
     1261 cgaaaatcaa gattgaaaca ttttcttgga atgacttcta tactaaatgg actacaggtt
     1321 tagcaaatgg aaatgtgcca gatatcagta cagctcttcc taaccaagta atggaaatgg
     1381 tcaactcaga cgctttggtt ccgctaaatg attctatcaa gcgtattgga caagataaat
     1441 ttaacgaaac tgccttaaat gaagcaaaaa tcggagatga ttactactct gttcctcttt
     1501 attcacatgc acaagtcatg tgggttagaa cagatttgtt aaaagaacat aatattgagg
     1561 ttcctaaaac ttgggatcaa ctctatgaag cttctaaaaa attgaaagaa gctggagttt
     1621 atggcttgtc tgttccgttt ggaacaaatg acttaatggc aacacgtttc ttgaacttct
     1681 acgtacgtag tggtggagga agcctcttaa caaaagatct taaagcagac ttgacaagcc
     1741 aacttgctca agatggtatt aaatactggg ttaaattgta taaagaaatc tcacctcaag
     1801 attctttgaa ctttaatgtc cttcaacaag ctaccttgtt ctatcaagga aaaacagcat
     1861 ttgactttaa ctctggcttc catatcggag gaattaatgc caacagtcct caattgattg
     1921 attcgattga tgcttatcct attccaaaaa tcaaagagtc tgataaagat caaggaattg
     1981 aaacctcaaa cattccaatg gttgtttgga aaaattcaaa acatccagaa gttgctaaag
     2041 cattcttaga agcactttat aatgaagaag actacgttaa attccttgat tcaactccag
     2101 taggtatgtt gccaactatt aaggggatta gcgattctgc agcctataaa gaaaatgaaa
     2161 ctcgtaagaa atttaaacat gctgaagaag taattactga agctgttaaa aaaggtactg
     2221 ctattggtta tgaaaatgga ccaagtgtac aagctggtat gttaactaac caacacatta
     2281 ttgaacaaat gttccaagat atcattacaa atggaacaga tcctatgaaa gcagcaaaag
     2341 aagcagaaaa acaattaaat gatttatttg aggctgttca gtagatgtaa aagactagaa
     2401 aataggtggg ctagtgagct gaaaagctct agcccaatct tgtaaaagaa gggagaagga
     2461 gaatggttaa agaacgtaat ttaactcgct ggatatttgt tttgccagct atgattatcg
     2521 taggattact ctttgtttat ccgtttttct cgagtatttt ttatagcttt accaataagc
     2581 atttgattat gcctaattat aaatttgttg gtttggctaa ctataaagct gtgctatcag
     2641 atcccaactt ctttaatgcg ttctttaatt caattaagtg gaccattttc tcattagttg
     2701 gtcaagtttt agtagggttt gtattggctt tagctcttca cagagtacgc cacttcaaga
     2761 aattatatag gaccttattg attgttcctt gggcatttcc taccatcgtc attgcctttt
     2821 cttggcagtg gattctaaac ggggtttatg gctacttacc taatctaatc gtaaaattag
     2881 gtttaatgga acatacacct gcatttttga cagatagtac atgggcattc ctatgtttgg
     2941 tgtttatcaa catttggttt ggagcaccaa tgattatggt taatgtgctt tcagctttgc
     3001 aaacagtacc agaagaacaa tttgaggctg ctaagataga tggtgcttca agttggcagg
     3061 tgttcaagtt tatcgtcttt ccacatatta aagtggttgt aggacttcta gttgttttga
     3121 gaactgtatg gatctttaat aactttgaca ttatctacct cattactggt ggtggaccag
     3181 ccaatgctac aacgacgctt ccaatttttg cttacaacct gggctgggga actaaattgt
     3241 tgggtcgtgc ttcagcagtt acagtattgc tctttatctt cttggtggcg atttgcttta
     3301 tctactttgc tatcatcagt aagtgggaaa aggagggtag aaaataatga agaagaaatc
     3361 cagtatttat ttagatattc tctcacatgt acttttagtt ggtgcgacca tcgttgcaat
     3421 tttcccattg gtatggatta tcatatcttc tgtcaaaggg aaaggggaat taactcagta
     3481 tccaacacga ttttggcctg aacagtttac attagattat ttcactcatg ttatcaacga
     3541 tttgcacttc attgataaca ttcgaaacag tttaatcatt gccttggcta caaccctcat
     3601 tgcgattatt atttctgcta tggcagccta tggtattgtt cgattctttc ctaaattggg
     3661 agcaatcatg tcgagactac tcgtcattac ctacattttc ccaccaattt tgttagcaat
     3721 tccctattca attgccattg ctaaagttgg gttaacaaat agtttatttg gcttgatgat
     3781 ggtttatcta tcttttagtg ttccatatgc agtttggctc ttagttggat ttttccaaac
     3841 agttccaatt ggaattgaag aagcggctag aattgatggt gcaaataaat ttgttacgtt
     3901 ttataaagtt gtgctaccga ttgtagcacc aggtattgta gcaacagcta tttatacatt
     3961 tatcaatgct tggaatgaat tcctgtatgc cttgattttg attaacaata caggaaagat
     4021 gacagtagca gtagcccttc gttcacttaa tggttcagaa atactagact ggggagatat
     4081 gatggcagcg tctgttattg tagttcttcc atcaattatt ttcttctcta tcatccaaaa
     4141 taagattgca agtggattat cagaaggatc tgtgaagtag acgaaagaag gaaaaaaatg
     4201 aataaaagag gtctttattc aaaactagga atttccgttg taggcattag tcttttaatg
     4261 ggagtcccca ctttgattca tgcgaatgaa ttaaactatg gtcaactgtc catatctcct
     4321 atttttcaag gaggctcata tcaactgaac aataagagta tagatatcag ccctttgtta
     4381 ttagataaat tgtctggaga gagtcagaca gtagtaatga aatttaaagc agataaacca
     4441 aactctcttc aagctttgtt tggcctatct aatagtaaag caggctttaa aaataattac
     4501 ttttcaattt tcatgagaga ttctggtgag ataggtgtag aaataagaga cgcccaaaag
     4561 ggaataaatt atttattttc tagaccagct tcattatggg gaaagcataa aggacaggca
     4621 gttgaaaata cactagtatt tgtatctgat tctaaagata aaacatacac aatgtatgtt
     4681 aatggaatag aagtgttctc tgaaacagtt gatacatttt tgccaatttc aaatataaat
     4741 ggtatagata aggcaacact aggagctgtt aatcgtgaag gcaaggaaca ttacctcgca
     4801 aaaggaagta ttgatgaaat cagtctattt aacaaagcaa ttagtgatca ggaagtttca
     4861 aatattccct tgtcaaatcc atttcagtta attttccaat caggagattc tactcaagct
     4921 aactatttta gaataccgac actatataca ttaagtagtg gaagagttct atcaagtatt
     4981 gatgcacgtt atggtgggac tcatgattct aaaagtaaga ttaatattgc cacttcttat
     5041 agtgatgata atgggaaaac gtggagtgag ccaatttttg ctatgaagtt taatgactat
     5101 gaggagcagt tagtttactg gccacgagat aataaattaa agaatagtca aattagtgga
     5161 agtgcttcat tcatagattc atccattgtt gaagataaaa aatctgggaa aacgatatta
     5221 ctagctgatg ttatgcctgc gggtattgga aataataatg caaataaagc cgactcaggt
     5281 tttaaagaaa taaatggcca ttattattta aaactaaaga agaatggaga taacgatttc
     5341 cgttatacag ttagagaaaa tggtgtcgtt tatgatgaaa caactaataa acctacaaat
     5401 tatactataa atgataagta tgaagttttg gagggaggaa agtctttaac agtcgaacaa
     5461 tattcggttg attttgatag tggctcttta agagaaaggc ataatggaaa acaggttcct
     5521 atgaatgttt tctacaaaga ttcgttattt aaagtgactc ctactaatta tatagcaatg
     5581 acaactagtc agaatagagg agagagttgg gaacaattta agttgttgcc tccgttctta
     5641 ggagaaaaac ataatggaac ttacttgtgt cccggacaag gtttagcatt aaaatcaagt
     5701 aacagattga tttttgcaac atatactagt ggagaactaa cctatctcat ttctgatgat
     5761 agtggtcaaa catggaagaa atcctcagct tcaattccgt ttgaaaatgc aacagcagaa
     5821 gcacaaatgg ttgaactgag agatggtgtg attagaacat tctttagaac cactacaggt
     5881 aagatagctt atatgactag tagagattct ggagaaacat ggtcggaagt ttcgtatatt
     5941 gatggaatcc aacaaacttc atatggcaca caagtatctg caattaaata ctctcaatta
     6001 attgatggaa aagaagcagt cattttgagt acaccaaatt ctagaagtgg ccgtaaggga
     6061 ggtcaattag ttgtcggttt agtcaataaa gaagatgata gtattgattg gaaataccac
     6121 tatgatattg atttgccttc gtatggttat gcctattctg cgattacaga attgccaaat
     6181 catcacatag gtgtactgtt tgaaaaatat gattcgtggt cgagaaatga attgcattta
     6241 agcaatgtag ttcagtatat agatttggaa attaatgatt taacaaaata aaggagaaaa
     6301 acatggttaa atacggtgtt gttggagcag ggtattttgg agctgaattg gctcgctaca
     6361 tgcaaaaaaa tgatggagca gagattactc ttctctatga tccagataat gcagaggcga
     6421 ttgcagaaga attgggagca aaagtagcaa gttccttaga tgagttggtt tctagcgatg
     6481 aagtagactg tgttatcgtc gcaactccaa ataatcttca taaggaaccg gttattaagg
     6541 ctgcacagca tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct tatcaagatt
     6601 gtcgcgagat ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca ggacatatta
     6661 tgaatttctt taatggtgtt catcatgcaa aagaactcat taatcaagga gttatcggag
     6721 acgttctata ttgtcataca gctcgtaatg gttgggaaga acaacaaccg tcagtatcat
     6781 ggaaaaaaat tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat gaattggatt
     6841 gcgttcaatt ccttatgggg ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg
     6901 cccatgaagg tgaacatttc ggtgatgaag atgatatgat ttttgtcaat atggaatttt
     6961 ctaataagcg ttttgccttg ttagaatggg gttcagctta tcgttggggt gaacattatg
     7021 tcttaatcca aggaagcaaa ggtgccatcc gcttagactt attcaactgt aaaggaactc
     7081 ttaagctaga tgggcaagaa agctatttct tgattcacga atcgcaagaa gaagatgatg
     7141 atcggactcg tatctatcat agtacagaga tggatggagc aattgcttat ggtaaaccag
     7201 gtaaacgtac tccattatgg ctatcatctg tcattgataa agaaatgcgc tatctgcatg
     7261 agattatgga aggagcccca gtatcagaag aatttgcaaa acttttgaca ggtgaagctg
     7321 ccctagaagc aattgctact gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag
     7381 taaaattgtc agaaattgta aaataaattt tggtattctc ctatttatag gtcgacttgc
     7441 tcctctgaaa gtacttttag aggagctgtt tgactttgct agtttttgaa actgaaatct
     7501 attatactac aaactattga aagcgtttta attttaaggt ataataatct catagaaata
     7561 aagaaaagga ggaaagagga tgccacagat tagcaaagaa gccttgattg agcaaatcaa
     7621 agatggaatc atcgtttctt gtcaggctct tcctcatgaa ccgctttata cagaagcggg
     7681 aggggtgatt cccttgctgg tcaaagcggc tgagcaaggt ggagcagtcg gtatccgagc
     7741 aaacagtgtt cgcgatatca aggaaattaa ggaagtcact aaacttccaa tcattgggat
     7801 tatcaaacgt gattatccac ctcaggaacc cttcatcacg gctactatga aagaagttga
     7861 tgaattggca gaactggaca tcgaggtgat tgctctggat tgtaccaagc gtgaacgcta
     7921 cgatggtttg gaaattcaag agttcattcg tcaggttaag gagaaatatc ctaatcagct
     7981 tttgatggct gatactagta tcttcgaaga agggctagca gctgtagaag caggaattga
     8041 ctttgtcgga acaaccttat caggctacac atcctacagt ccaaaagtag acggtccaga
     8101 ttttgaattg attaagaaac tctgtgatgc cggtgtagat gtcattgcag aaggaaaaat
     8161 tcatacacca gaacaagcca aacaaatcct tgaatatgga gtgcgaggca tcgttgttgg
     8221 tggcgccatt actagaccaa aagagattac agaacgcttc gttgctagtc ttaaataaga
     8281 tgtgagaggg agttttatgt ttaaagtttt acaaaaagtt ggaaaagctt ttatgttacc
     8341 tatagctata cttcctgcag caggtctact tttggggatt ggtggtgcac tttcaaaccc
     8401 aaccacgata gcaacttatc caatactaga caatagtatt tttcaatcaa tattccaagt
     8461 aatgagctct gcaggagagg ttgtattcag taatttgtca ctacttctct gtgtgggatt
     8521 atgtattggc ttagcgaaac gagataaagg aaccgctgcg ttagcaggag taactggtta
     8581 cttagttatg actgcaacga tcaaagcttt ggtaaaactt tttatggcag aaggatctgc
     8641 aattgatact ggagttattg gagcattagt tgtcggaata gttgccgtat atttgcacaa
     8701 ccgatataac aatattcaat taccttccgc tttaggattc tttggaggtt cacgcttcgt
     8761 tcctattgtt acatcgttct cttctatctt gattggcttt gtcttctttg ttatttggcc
     8821 acctttccaa caacttcttg tttctacagg tggatatatt tctcaggcgg gtccaattgg
     8881 aacttttcta tatggatttt taatgagact ttctggagca gtaggcttac atcatataat
     8941 ttaccctatg ttttggtata ctgaacttgg tggtgttgaa actgttgcag gacaaacagt
     9001 ggttggagct caaaaaatat tttttgctca attagccgat ccggcccatt ctggattatt
     9061 tacagaagga acaaggtttt ttgcaggtcg tttctcaaca atgatgttcg gtttaccggc
     9121 tgcctgttta gcgatgtacc atagtgttcc taaaaatcgt cgtaaaaaat acgcgggttt
     9181 gttttttgga gttgctttaa catcttttat taccggtatt acagaaccaa ttgaatttat
     9241 gtttctattc gtcagtccgg ttctatatgt tgttcacgca ttccttgatg gtgttagctt
     9301 ctttattgca gacgtcttaa atatttcaat aggaaacaca ttttcaggag gtgtaatcga
     9361 tttcacttta tttggaattt tgcaggggaa cgctaagacg aattgggttc ttcagattcc
     9421 aattggactt atttggagtg ttttgtatta tattattttt agatggttca ttactcaatt
     9481 caacgttcta acgccaggac gaggagaaga agtagattct aaagaaattt ctgaatccgc
     9541 agattcaact tcaaatactg cagattattt aaaacaggat agcctacaaa ttatcagagc
     9601 cttgggtgga tcaaataata tagaagatgt agatgcttgt gtgacacgtt tacgtgtagc
     9661 tgtaaaagaa gttaatcaag ttgataaagc acttttaaaa caaattggtg cagttgatgt
     9721 cttagaagtg aagggtggca ttcaagcaat atatggagca aaagcaatct tatataaaaa
     9781 tagtattaat gaaattttag gtgtagatga ttaagtactt actgacttaa taaaaaacag
     9841 aggagagtga tggatgagta ggatgaaatg aaatcgcata caagaaataa agaactcatt
     9901 atccaagttg gatacgctta ttacatagga gaatacaaat gaaatttaga aaattagctt
     9961 gtacagtact tgcgggtgct gcggttcttg gtcttgctgc ttgtggcaat tctggcggaa
    10021 gtaaagatgc tgccaaatca ggtggtgacg gtgccaaaac agaaatcact tggtgggcat
    10081 tcccagtatt tacccaagaa aaaactggtg acggtgttgg aacttatgaa aaatcaatca
    10141 tcgaagcgtt tgaaaaagca aacccagata taaaagtgaa attggaaacc atcgacttca
    10201 agtcaggtcc tgaaaaaatc acaacagcca tcgaagcagg aacagctcca gacgtactct
    10261 ttgatgcacc aggacgtatc atccaatacg gtaaaaacgg taaattggct gagttgaacg
    10321 acctcttcac agatgaattt gttaaagatg tcaacaatga aaacatcgta caagcaagta
    10381 aagctggaga caaggcttat atgtatccga ttagttctgc cccattctac atggcaatga
    10441 acaagaaaat gttagaagat gctggagtag caaaccttgt aaaagaaggt tggacaactg
    10501 atgattttga aaaagtattg aaagcactta aagacaaggg ttacacacca ggttcattgt
    10561 tcagttctgg tcaaggggga gaccaaggaa cacgtgcctt tatctctaac ctttatagcg
    10621 gttctgtaac agatgaaaaa gttagcaaat atacaactga tgatcctaaa ttcgtcaaag
    10681 gtcttgaaaa agcaactagc tggattaaag acaatttgat caataatggt tcacaatttg
    10741 acggtggggc agatatccaa aactttgcca acggtcaaac atcttacaca atcctttggg
    10801 caccagctca aaatggtatc caagctaaac ttttagaagc aagtaaggta gaagtggtag
    10861 aagtaccatt cccatcagac gaaggtaagc cagctcttga ataccttgta aacggatttg
    10921 cagtattcaa caataaagac gacaagaaag tcgctgcatc taagaaattc atccagttta
    10981 tcgcagatga caaagagtgg ggacctaaag acgtagttcg tacaggtgct ttcccagtcc
    11041 gtacttcatt tggaaaactt tatgaagaca aacgcatgga aacaatcagc ggctggactc
    11101 aatactactc accatactac aacactattg atggttttgc tgaaatgaga acactttggt
    11161 tcccaatgtt gcaatctgta tcaaatggtg acgaaaaacc agcggatgct ttgaaagcct
    11221 tcactgaaaa agcaaacgaa acaatcaaaa aagctatgaa acaatagtcc ttagttattc
    11281 tataaaaagt agttttttaa agaacctaag agtgtatacc cccttttccc tctacacaga
    11341 tagtgtaaga aaagggggct tttgtttaaa atgtaagaaa ctgtcacgaa attaaaatga
    11401 agttcttaca taagcgaatc ataaaaaatt tcattttgat tttaaaacag ttcaagaaag
    11461 tcaaaaaatt attctatttg aaagagaggt gccgactgtg aaagtcaata aaatccgtat
    11521 gcgggaaaca gtgatttcct acgctttcct agcaccagta ttattcttct ttgtcatctt
    11581 tgtgttggct ccgatggtga tgggcttcat tacaagtttc tttaactact caatgactaa
    11641 atttgagttt gtaggcttgg ataactatat ccgtatgttt aaagatcctg tctttacaaa
    11701 atctctgatt aacacagtta ttttggttat tggatctgta ccagttgttg ttctattctc
    11761 actctttgta gcatctcaga cctatcatca aaatgtcatt gccagatcct tctaccgttt
    11821 cgtcttcttc cttcctgttg taacgggtag tgttgccgtg acagttgttt ggaaatggat
    11881 ttatgacccg ctatcaggga ttctaaactt tgtccttaag tcaagccaca tcatcagcca
    11941 aaacatttct tggttgggag ataaaaactg ggcattgatg gcgattatga ttattctctt
    12001 gaccacttca gttggtcagc ccatcatcct ttatatcgct gccatgggga atattgacaa
    12061 ttcactggtt gaagcggcgc gtgttgatgg tgcaactgag tttcaagttt tttggaagat
    12121 taaatggcca agccttcttc caacaactct ttatattgca atcatcacaa caattaactc
    12181 attccagtgt tttgccttga ttcagctttt gacatctggt ggtccaaact actcaacaag
    12241 taccttgatg tactaccttt acgaaaaagc cttccaattg acagaatacg gctatgccaa
    12301 cacaattggt gtcttcttgg caatcatgat tgctatcgta agctttgttc aatttaaagt
    12361 acttggaaac gacgtagaat actaaagaaa ggagacagct atgcaatcta cagaaaaaaa
    12421 accattaaca gcctttactg ttatttcaac aatcattttg ctcttgttga ctgtgctgtt
    12481 catctttcca ttctactgga ttttgacagg ggcattcaaa tcacaacctg atacaattgt
    12541 tattcctcct cagtggttcc ctaaaatgcc aaccatggaa aacttccaac aactcatggt
    12601 gcagaaccct gccttgcaat ggatgtggaa ctcagtattt atctcattgg taaccatgtt
    12661 cttagtctgt gcaacctcat ctctagcagg ttatgtattg gctaaaaaac gtttctatgg
    12721 tcaacgcatt ctatttgcta tctttatcgc tgctatggcg cttccaaaac aagttgtcct
    12781 tgtaccattg gtacgtatcg tcaacttcat gggaatccac gatactctct gggcagttat
    12841 cttgcctttg attggatggc cattcggtgt cttcctcatg aaacagttca gtgaaaatat
    12901 ccctacagag ttgcttgaat cagctaaaat cgacggttgt ggtgagattc gtaccttctg
    12961 gagtgtagcc ttcccgattg tgaaaccagg gtttgcagcc cttgcaatct ttaccttcat
    13021 caatacttgg aatgactact tcatgcaatt ggtaatgttg acttcacgta acaatttgac
    13081 catctcactt ggggttgcga ccatgcaggc tgaaatggca accaactatg gtttgattat
    13141 ggcaggagct gcccttgctg ctgttccaat cgtcacagtc ttcctagtct tccaaaaatc
    13201 cttcacacag ggtattacta tgggagcggt caaaggataa tactctgaga aaatctcttc
    13261 aaactacgtc agcgtcacct tgccatactt aagtattgcc tgcggttagc ttcctagttt
    13321 gttcttcaat tttcattgag tataggaaaa tcaatctatc aagatacaga agtatatttt
    13381 atagatttag agaatataga ggttataagt gtctacaaaa tggagggtat gcagttactt
    13441 tatgaagttt tgtcagacac ttataaactt aagaatggtt ttagttaact atcagaaacg
    13501 aaggaaagag tatgattttt gacgatttga aaaacatcac cttttacaaa gggattcatc
    13561 ccaatttaga caaggctatc gactatctct accaacatcg taaagattca ttcgaattag
    13621 gaaagtatga gattgatgga gataaagtct ttctagttgt tcaggaaaat gtcctcaatc
    13681 aagttgagaa taatcgattt gaacaccata agaactatgc agatttgcat ttgctgatag
    13741 aagggcatga atattcgagc tacggttcac gtatcaaaga cgaggcagta gcattcgacg
    13801 aagcgagtga cattggcttt gttcattgtc atgaacacta cccactcttg ttgggttatc
    13861 acaattttgc gattttcttc ccaggtgagc cacatcagcc aaatggttat gcaggcatgg
    13921 aagaaaaggt tcgaaaatat ctctttaaaa ttttgattga ttaaaaatag gatgaattgt
    13981 ttttttgtaa agctttgata atactctacc atgaaattga tctttgtgag gtagagaaat
    14041 gagaataaaa tatttaaaaa ttggtatctt ctaagtatgc tgcaagagct agtttcttag
    14101 atggacaggg gattacagtt gatgagatgg cttggataat taggggcatt gtgactgcat
    14161 tgattggtag atacataaaa ttaggtactt atgcagttaa gtatggtatt agtatggcgc
    14221 gctcgatctt aagtagggca gctgcaactg cggcagcaag agtaggatta ttgactaaga
    14281 tttttggatg gattttacga atagctgtgc tcgcagctga tgtatatggt aattttgcca
    14341 acaatattgc tgtagcttgg gatgcacatg ataaaatccc taacaatggt cgtataaact
    14401 tttaaaatgc gagaatgaaa gcactttgta tttttttatt gtatatgtta gcttggacag
    14461 tgcttgcaat gataatccgt ggagggctag atggatttga tgaacacact tggcgtacta
    14521 ttttaattgc ttcgctgtcc gggatatata tagattatat gtccatagat aaaagtagaa
    14581 aaaagtccaa aagaaaaaag aaaaaataga tttgttcatg gtagggactt atgaaagctt
    14641 tactgacaaa aaagaaaaca gtttacaaag aaaaatgatg gaggagcaaa catggcacaa
    14701 aaaggagtaa gccttatcaa ggcagcattt gatacagata actttctcat gcgttttagt
    14761 gagaaagtct tggacatcgt gacagccaat cttctttttg tcgtctcttg tttgcccatc
    14821 gtgacgattg gagtggctaa aatcagcctc tacgagacca tgttcgaagt taagaagagc
    14881 agacgggtgc ctgtttttaa aatctatcta agatctttca agcaaaatct gaaactaggt
    14941 cttcagctgg gtttaatgga gttaggaatt gtgtttctta ccctttcaga tctctatctt
    15001 ttctggggtc aaacagctct gcccttccaa ttgctgaaag ccatttgtct aggcattctg
    15061 attttcctta cgattgtgat gttggctagc tatccaatcg cggcacgtta tgatttaact
    15121 tggaaagaag tgttacaaaa agggcttatc ttggctagtt ttaactttcc ttggttcttc
    15181 ctcatgttag ccattcttgt cctcattgtg atggttcttt atctgtccgc cttcagtcta
    15241 ctcttaggtg gctcagtctt cctacttttt gggtttggac tattggtctt tatccagact
    15301 ggattgatgg agaaaatttt cgcaaaatac caataggagc cttatttctg aaactacttt
    15361 caaaggctcc aaacgctatt ctataagcga gaaactaaaa tctaagtgtc tataagatat
    15421 tgaaagcctt ttcggtaaag tgtatactaa agaagtaaag aaaaatctgc tttagcagaa
    15481 aataaaaata ataggagaaa atctatgtca gatttgaaaa aatacgaagg tgtcattcca
    15541 gccttctacg catgttatga tgagcaagga gaagtaagtc cagagcgtac gcgtgccttg
    15601 gttcaatact tcattgataa aggtgttcaa ggtctttatg tcaatggttc ttctggtgaa
    15661 tgtatctacc aaagcgttga agatcgcaag ttgattttgg aagaagtcat ggcggtagcc
    15721 aaaggtaaat tgaccattat tgcccatgtt gcttgcaata atactaaaga tagtatggaa
    15781 cttgctcgcc atgctgaaag cttgggagta gatgctattg caacgattcc accaatttat
    15841 ttccgcttgc cagaatactc agttgccaaa tactggaacg atatcagttc tgcagctcca
    15901 aacacagact acgtgattta caacattcct caattggcag gggttgcttt gactccaagc
    15961 ctttacacag aaatgttgaa aaatcctcgt gttatcggtg tgaagaactc ttctatgcca
    16021 gttcaagata tccaaacctt tgtcagcctt ggtggagaag accatatcgt ctttaatggt
    16081 cctgatgagc agttcctagg aggacgcctc atgggggcta gggctggtat cggtggtact
    16141 tatggtgcta tgccagaact cttcttgaaa ctcaatcagt tgattgcgga taaggaccta
    16201 gaaacagcgc gtgaattgca gtatgctatc aacgcaatca ttggtaaact cacttctgct
    16261 catggaaata tgtacggtgt catcaaagaa gtcttgaaaa tcaatgaagg cttgaatatt
    16321 ggatctgttc gttcaccatt gacaccagtg actgaagaag atcgtccagt tgtagaagcg
    16381 gctgctgcct tgattcgtga aaccaaggag cgcttcctct aatctaaaag gaggtattta
    16441 tgacatatta cgttgcaatt gatatcggtg gaaccaacat caagtatggt ttggttgatc
    16501 aagaggggca acttcttgaa tcgcatgaaa tgccaactga ggcgcataag ggtggacctc
    16561 atatcttaca aaagaccaaa gatatcgtag ctagttattt agaaaaaggc ccagtagcag
    16621 gtgttgccat atcttctgct gggatggtgg atccggataa gggtgagatt ttctatgctg
    16681 ggccgcaaat ccctaactac gcaggcaccc agttcaaaaa ggaaatcgaa gaaagcttta
    16741 ctattccttg tgagattgaa aatgatgtca actgtgcagg tcttgctgag gcagtatctg
    16801 gttcaggcaa gggagcaagt gtgacacttt gcttgaccat tggaaccggt atcggtggtt
    16861 gcttgattat ggataggaaa gtcttccatg gttttagcaa ttcagcctgt gaagtcgggt
    16921 atatgcatat gcaggatgga gcttttcaag acttggcttc tacaacagct ttagtgaaat
    16981 atgtagctga agcccatgga gaagatgttg atcagtggaa tggccgtaga attttcaaag
    17041 aagctacgga aggcaataaa ttctgcatgg aaggtattga ccgcatggta gactatctag
    17101 gaaaaggtct ggcaaatatt tgctacgttg ccaatccaga agtggtcatt ctcggtggcg
    17161 gtatcatggg acaagaggcg attctcaaac cgaaaatccg cacagccttg aaagaggctt
    17221 tggtaccaag tttggctgag aaaacaagat tagaattcgc caagcaccaa aataccgcag
    17281 gcatgttggg tgcttattat cattttaaaa caaaacaatc ctagtttggc ttagccaaac
    17341 taggattttc tgacacgttt ttgtctacga tagccgttga gtttcttatt ttcccaatag
    17401 ctattaaaga ttttctcctt gctttcacga ttgatttcca aaaagtaggc ataaatcaaa
    17461 tcgataaaga agagcatagg aagttgagcg gatatacgtt ggatgtagga aggctggctg
    17521 tgggtagcta caagaacggt ctcagtatag gcctggctat ctttattggg aacacttgaa
    17581 aagagtacag tctttgctcc catctccttg gcatccaata gactatctaa aatagaagga
    17641 gttgagcctg aaagtgagaa accaagtacg agacaatttt cgtccataat gctggttgtc
    17701 caggcaaagc cgtcttgatc ggtcaaagct tcgcagacca cacccagacg catgaagcgt
    17761 aatttcattt cacgagcaac aaggccagaa cttcctgttc cgaagaagta gacacgctca
    17821 gcatcttcga ttaattgggc aattcgttct agttggactt cgtcaatcaa gtcttgtgtt
    17881 tgttccctca tattactata gcttctgagg actcgtttgg tcagtggact gtgcttggag
    17941 acttggttgg cttgattttc tgcctcatgt tggtattgga aaataaattc tcggtagcca
    18001 gtaaagccac actttttagc aaagcgggtc agtgcagctt gagagatatg taatttttga
    18061 gtgacctgtt gggaggaaag gtcatcttga atggtttctg cttgtaaaaa atagcgagcg
    18121 atttcttgct ctaggtctgt catttcttca aaatgtgaat caatgacagt tgcgatatct
    18181 ggtttgtcca tagggaaggc tcctttaaat gagtcgtgtt ggaaaaagac tagattattg
    18241 aacttttaca ttcattataa catataatat agggatggat aaataaaaac gtatcttact
    18301 gtaaaaacga aaaaaagctt ctttcttttc cataattttc tgctcaaatt gtggtacaat
    18361 taagagtaag attttaagtt agaaatgaga ctgatttgta tgagaaaatt taacagccat
    18421 tcgattccga ttcggcttaa tttattgttt tcaatcgtca ttttactctt tatgaccatt
    18481 attggtcgtt tgttgtatat gcaggttttg aacaaggatt tttatgaaaa aaagctagcc
    18541 tcagctagtc agaccaaggt cacaaccagt tctgctcgtg gggaaatcta tgatgctagt
    18601 ggaaaacctt tggtagaaaa tacgttaaag caggttgttt cctttacgcg tagcaataaa
    18661 atgacggcta cagacttaaa agaaatagct aaaaagttac tgacttatgt gagcatcagt
    18721 tcgccaaatt tgacagaacg ccagctggct gattactatt tggctgatcc tgaaatctat
    18781 aaaaaaacag tggaagctct cccaagtgag aaacgcttgg attcagatgg caatcgccta
    18841 tccgaatcag aactgtataa caatgctgtc gatagtgtcc caacaagtca actaaactat
    18901 acagaggatg aaaagaaaga aatctatctt tttagtcagt taaatgctgt tggaaacttt
    18961 gcgacaggaa ccattgtgac agatcctcta aatgattctc aggtggctgt tattgcctct
    19021 atttcaaagg agatgcctgg cattagtatt tctacttctt gggatcgaaa ggttttggaa
    19081 acttcccttt cttctatagt agggagtgta tccagtgaaa aagctggtct cccagcggaa
    19141 gaagcagaat cctatcttaa aaaaggctat tctctaaatg accgtgttgg aacctcctat
    19201 ttggaaaagc aatatgaaga gaccttacaa ggaaaacgct cggtaaaaga aatccatctg
    19261 gataaatatg gcaatatgga aagcgtggac acaattgagg aaggtagtaa gggaaacaat
    19321 atcaaactga ccattgattt ggccttccaa gatagcgtgg atgctttgct gaaaagttat
    19381 ttcaattccg agctaggaaa tggtggagct aaatattctg aaggtgtcta tgcagtcgcc
    19441 cttaacccaa aaacaggtgc tgttttatcc atgtcaggga tcaaacatga cctgaaaacg
    19501 ggagagttga ctcctgattc cttgggaacg gtaaccaatg tctttgtccc aggttcggtt
    19561 gtcaaggctg cgaccatcag ctcaggttgg gaaaatggtg ttttatcagg aaaccaaacc
    19621 ttaacagatc agcctattgt tttccaaggt tcagctccaa tttattcttg gtataaattg
    19681 gcatatggat cttttcctat tacagctgtg gaagccttgg agtattcatc caatgcttac
    19741 atggttcaaa ccgctcttgg aatcatgggc cagacctatc aaccaaatat gtttgttgga
    19801 accagcaatt tggaaacagc tatgggaaaa cttcgtgcga cctttggcga atatggcttg
    19861 ggggctgcga ccggaattga cctaccagat gaatctactg gatttgttcc caaagagtat
    19921 agctttgcta attacatcac caattccttt gggcagtttg ataactatac gcccatgcag
    19981 ttggctcagt atgtagcaac tattgcaaat aatggtgttc gtgtggctcc tcgtattgtt
    20041 gaaggcattt atggtaataa tgataaggga ggactgggtg acttgattca gcaactgcaa
    20101 ccgacagaga tgaataaggt caatatatcc gactccgata tgagcatctt gcaccaaggt
    20161 ttttatcagg ttgcccatgg tactagtgga ttgacaactg gacgtgcctt ttcaaatggt
    20221 gccttggtat ccattagcgg aaaaacaggt acagccgaaa gctatgtggc agatggtcag
    20281 caagcaacca ataccaatgc ggtggcctat gccccatctg ataatcccca aatcgctgtc
    20341 gcagtggtct ttcctcataa taccaatcta acaaatggtg taggaccttc cattgcgcgt
    20401 gacattatca atctgtatca aaaataccat ccaatgaact agaaaggaaa ttatgcttta
    20461 tccaacacct attgccaagt tgattgacag ttattctaag ttaccaggta tcgggattaa
    20521 gacggctacg cgtctggcct tttatacgat tgggatgtct gctgatgatg tcaatgaatt
    20581 tgcaaaaaat ctcctttctg ctaagagaga attgacatat tgttctattt gtggacgttt
    20641 gacagacgac gatccttgtt ctatctgtac tgattcgact cgtgaccaga caacaatttt
    20701 agttcttgag gatagtagag atgtggcagc catggaaaat atccaagaat accatggact
    20761 ctatcatgtc ctgcatggcc tcatttctcc tatgaatggt atcagtccgg acgatatcaa
    20821 tcttaagagc cttatgactc gtcttatgga tagtgaggtt tcagaagtga ttgtggcgac
    20881 taatgctaca gcggatggtg aagcgacctc catgtatctt tcacgtttgc tcaagccggc
    20941 tggtatcaag gttacgcgtc tagcacgagg tctcgctgtg ggagcggaca ttgagtatgc
    21001 ggacgaagtg acactcttac gagcgattga aaatcggaca gagttgtaag tgtaggcaaa
    21061 tttacgaact ccattcattt ataaaaaatc aaagaggctg aaaatcgttc ctatcggcct
    21121 ctttttgtat agtgtgatga gtagaatcag gttcaagttt taaaaaacca agcaaatatg
    21181 atatactaaa gagcgagtat tctagtagaa ttaggacaaa taatatgaaa caaacgatta
    21241 ttcttttata tggtggacgg agtgcggaac gcgaagtctc tgtcctttca gctgagagtg
    21301 tcatgcgtgc ggtcaattac gaccgtttca cagtcaagac tttctttatc agtcagtcag
    21361 gtgactctat caaaacgcag gaatttagtc atgctccggg gcaagaagac cgtctcatga
    21421 ccaatgaaac cattgattgg gataagaaag ttgcaccaag tgctatctac gaagaaggtg
    21481 cagtggtctt tccagtcctt cacgggccaa tgggagaaga tggctctgtt caaggattct
    21541 tggaagtttt gaaaatgcct tacgttggtt gcaacatttt gtcatcaagt cttgccatgg
    21601 ataaaatcac gactaagcgt gttctggaat ctgctggtat tgcccaagtt ccttatgtgg
    21661 ctatcgttga aggcgatgat gtgactgcta aaatagctga agtggaagaa aaattggctt
    21721 atccagtctt cactaagccg tcaaacatgg ggtctagtgt cggtatttct aagtctgaaa
    21781 accaagaaga actccgtcaa gccttaaaac ttgccttccg atatgacagc cgtgtcttgg
    21841 ttgagcaagg agtgaatgcc cgtgaaattg aggttggcct cttgggtaac tacgatgtca
    21901 agagcacgct acctggagaa gttgtcaagg acgttgcctt ttatgactac gatgccaagt
    21961 atattgataa caaggttact atggatattc ctgccaaaat cagtgatgat gtggtggctg
    22021 tcatgcgtca aaatgcagaa acagccttcc gtgccattgg tggccttggt ctatctcgtt
    22081 gcgatttctt ctatacagat aagggagaga tttttctcaa cgagctcaat accatgccag
    22141 gtttcaccca gtggtctatg tacccactac tttgggaaaa tatggggatc agctacccag
    22201 aactaatcga gcgtttggtt gaccttgcca aggaaagttt tgacaagcgc gaagcgcatt
    22261 tgatataaaa tgaaagagag ggtagaagcc agaaccatca ctgcaaggtg actagagttc
    22321 tcggacttca gcccttttta aaggagtaga aatgaaatta acaatccatg aaattgccca
    22381 agttgttgga gccaaaaatg atatcagtat ctttgaggac actcagttag aaaaagctga
    22441 gtttgatagt cgtttgattg gaactggaga tttatttgtg ccacttaaag gtgcgcgtga
    22501 tggccatgac tttattgaaa cagcctttga aaatggtgca gcagtaacct tgtctgagaa
    22561 agaggtctca aatcatcctt acattttagt agatgatgtt ttgacagcct ttcaatccct
    22621 agcatcctac tatcttgaaa aaacgactgt tgatgtcttt gctgttacag gttcaaatgg
    22681 caagacaacg actaaggata tgttggcgca tttactgtca acaagataca agacctacaa
    22741 aacacaaggc aattacaata atgagattgg ccttccttac acagttcttc atatgcctga
    22801 aggaacagaa aagttggttt tggagatggg acaggatcac ttgggagata ttcatctctt
    22861 gtctgaattg gctcgtccaa aaacagccat cgtgaccttg gttggagaag ctcatttggc
    22921 ctttttcaaa gatcgttctg agattgctaa aggaaaaatg caaattgcag acggaatggc
    22981 ttcaggttcc ttgcttttag cgccggctga ccctatcgta gaggactatt tgccaattga
    23041 taaaaaggtg gttcgttttg gtcaaggagc agagctggaa attactgact tggttgagcg
    23101 taaggacagt ctgaccttta aggctaattt cttggaacaa gcccttgatt tgccagtaac
    23161 tggcaagtac aatgcgacaa atgctatgat tgcatcctat gttgccttgc aagaaggagt
    23221 ttcagaggag caaattcgtt tggcattcca acatcttgaa ttgacgcgta accgtaccga
    23281 gtggaagaaa gcagccaatg gagcagatat cctgtcagat gtttacaatg ccaatccaac
    23341 tgctatgaaa ctgattttag agactttctc tgccattcca gccaatgaag gtggcaagaa
    23401 aattgcagtg ttggcggata tgaaggagct tggtgaccag tctgttcaac ttcataatca
    23461 gatgattttg agcctctccc cagatgtgct tgatatcgtt attttctatg gagaagatat
    23521 tgctcagttg gctcaattgg ccagtcaaat gtttccaatc ggccacgttt actacttcaa
    23581 gaaaacagaa gaccaggatc aatttgaaga cctagtcaag caggttaagg aaagccttgg
    23641 agcctatgac caaatcttgc taaaaggttc taactctatg aatctagcca aattggtaga
    23701 aagtttagaa aatgaatgca agtgattttg ctaagtatct tcaaagaatg attgctctta
    23761 cagatactgg actaaccttt acaaaggatc cgtttgaccg tgagcgctac gaagacttgc
    23821 gaagtctgtt atctgaaatg ttgaatcagg tatcagacct tgatgcagac gaagtggcag
    23881 aactcttgaa accgacctcc gcttatgcga ctcctttaat ggacgtccgt gcttggatag
    23941 ttgaggatga aaaaatttgt ctggttaggg gacaaggaga gaatgattgg gctttgccag
    24001 gtggctttgg cgaggtcggt tattcaccaa ctgaaaatat tctcaaggaa attgaagaag
    24061 aaaccggttt taaagccaaa gttgaacgac tactagctgt ttttgatacc aatcgtttcc
    24121 aactacagag caaacaatat gcaaagtttg tttttgaatg taagcttctc gatggacaat
    24181 ttcaagaaaa tcaagaaatc gctgaccttc aattttttgc aattgaccaa ctgccgaatt
    24241 tatctgaaaa acgcattacc aaggagcaaa tagagcttct ttggcaggtt tatcaaggtc
    24301 atagggggca atatcttgac taagaagatg attatcgtat ttctaaatcc atttttaaca
    24361 actagcatgg tataataata tgcaggaaaa ttttgaatta tgaggaagac tagatgaatt
    24421 tatgggatat tttctttacg actcaggcaa ccgagccgcc caaatttgac cttttttggt
    24481 atgttagcct atttacgctc ttagccttaa ccttttatac agcccatcgc tatcgtgaaa
    24541 ataaggttta ccaacgattt ttccaaatct tgcagactgt tcagttaatc cttctttatg
    24601 gttggtactg ggtcaatcat atgccactgt cagaaagcct acccttttac cattgccgta
    24661 tggctatgtt tgtggtactc ttgcttcctg gtcaatccaa atataaacaa tactttgcat
    24721 tattgggaac atttgggaca ttagcagcct ttgtttatcc agtgccagat gcttaccctt
    24781 ttccacatat caccattcta tcctttatct ttggtcattt agcactcttg gggaactctc
    24841 tagtttatct attgagacag tataatgcgc gattgctgga tgtgaaggga atttttctca
    24901 tgacctttgc cctaaatgcc ttgatttttg tggtcaattt ggtgacaggt ggcgattacg
    24961 gatttttgac aaaaccgcca ttggttgggg atcacggtct agtagctaat tatttacttg
    25021 tttcaattgt gctggtagct actatcagtt tgactaagaa aatcttagaa ttctttttag
    25081 ctcaagaagc agaaaaaatg attgcaaagg aagcttaaca cagagctttc ttttttgctc
    25141 ttagagagtt tttacaagca gcttataaaa taagaatttc tgaatagaca aactcaaaaa
    25201 atggctggga aatttaggaa aaaagcaagc acgattaaat tttttgtgtt ataatatttt
    25261 gtgaatagct atgcctatgt ttagctatgg aataatacga agtgcgaaac ttggaagata
    25321 gagaggaagc gatgtaatgg ctagagaagg cttttttaca ggtctagata ttggaacaag
    25381 ctctgtcaag gtgcttgtgg ccgagcagag aaatggtgaa ttaaatgtaa ttggcgtgag
    25441 taatgccaaa agtaaaggtg taaaggatgg aattattgtt gatattgatg cagcagcaac
    25501 tgctatcaag tcagccattt cccaagcgga agaaaaggca ggcatttcga ttaaatcagt
    25561 gaatgtcggc ttgcctggta atcttttgca ggtagaacca actcagggga tgattccagt
    25621 aacatctgat actaaggaaa ttacggatca agatgttgaa aatgttgtca aatcagcttt
    25681 gacaaagagt atgacacctg accgtgaagt cattaccttt attcctgaag aatttattgt
    25741 ggatggtttc caagggattc gtgacccacg tggcatgatg ggggttcgcc ttgaaatgcg
    25801 tggtttgctt tatacaggac ctcgtactat cttgcacaat ttgcgtaaga cggttgagcg
    25861 tgcaggtgtt caggttgaaa atgttatcat ttcaccacta gcaatggttc agtctgtttt
    25921 gaacgaaggg gaacgtgaat ttggtgctac agtgattgat atgggggcag gtcaaacgac
    25981 tgtcgctaca atccgtaatc aagaactcca gttcacacat attctccaag aaggtggaga
    26041 ttatgtaact aaagatatct ccaaggtttt gaaaacctct cgcaaattag cggaaggctt
    26101 aaaactgaat tacggggaag cctatccgcc tcttgcaagc aaagaaacct tccaagtaga
    26161 ggttattgga gaagtagaag cagtcgaagt gacggaagcc tacttgtcag aaattatttc
    26221 tgcacgaatc aagcacatcc ttgaacaaat caagcaagaa ttagatagaa ggcgtctatt
    26281 ggacctccct ggtggtattg tcttaatcgg tgggaatgcc attttaccag gtatggttga
    26341 gcttgctcag gaagtctttg gcgtccgtgt caagctttat gttccaaatc aagttggtat
    26401 ccgtaatcca gcctttgcgc atgtgattag tttatcagaa tttgcgggtc aattaacaga
    26461 agttaatctt ttggctcagg gagcgataaa aggtgagaat gacttaagtc atcagccaat
    26521 tagttttggt gggatgctgc aaaaaacagc tcagtttgta caatcaacgc ctgttcaacc
    26581 agctcctgct ccagaagtag agccggtggc gcctacagaa ccaatggcgg atttccaaca
    26641 agcttcacaa aataaaccga aattagcaga tcgtttccgt ggcttgatcg gaagcatgtt
    26701 tgacgaataa agaggaaaaa taaattatga cattttcatt tgatacagct gctgctcaag
    26761 gggcagtgat taaagtaatt ggtgtcggtg gaggtggtgg caatgccatc aaccgtatgg
    26821 tcgacgaagg tgttacaggc gtagaattta tcgcagcaaa cacagatgta caagcattga
    26881 gtagtacaaa agctgagact gttattcagt tgggacctaa attgactcgt ggtttgggtg
    26941 caggaggtca acctgaggtt ggtcgtaaag ccgctgaaga aagcgaagaa acactgacgg
    27001 aagctattag tggtgccgat atggtcttca tcactgctgg tatgggagga ggctctggaa
    27061 ctggagctgc tcctgttatt gctcgtatcg ccaaagattt aggtgcgctt acagttggtg
    27121 ttgtaacacg tccctttggt tttgaaggaa gtaagcgtgg acaatttgct gtagaaggaa
    27181 tcaatcaact tcgtgagcat gtagacactc tattgattat ctcaaacaac aatttgcttg
    27241 aaattgttga taagaaaaca ccgcttttgg aggctcttag cgaagcggat aacgttcttc
    27301 gtcaaggtgt tcaagggatt accgatttga ttaccaatcc aggattgatt aaccttgact
    27361 ttgccgatgt gaaaacggta atggcaaaca aagggaatgc tcttatgggt attggtatcg
    27421 gtagtggaga agaacgtgtg gtagaagcgg cacgtaaggc aatctattca ccacttcttg
    27481 aaacaactat tgacggtgct gaggatgtta tcgtcaacgt tactggtggt cttgacttaa
    27541 ccttgattga ggcagaagag gcttcacaaa ttgtgaacca ggcagcaggt caaggagtga
    27601 acatctggct cggtacttca attgatgaaa gtatgcgtga tgaaattcgt gtaacagttg
    27661 tcgcaacggg tgttcgtcaa gaccgcgtag aaaaggttgt ggctccacaa gctagatctg
    27721 ctactaacta ccgtgagaca gtgaaaccag ctcattcaca tggctttgat cgtcattttg
    27781 atatggcaga aacagttgaa ttgccaaaac aaaatccacg tcgtttggaa ccaactcagg
    27841 catctgcttt tggtgattgg gatcttcgcc gtgaatcgat tgttcgtaca acagattcag
    27901 tcgtttctcc agtcgagcgc tttgaagccc caatttcaca agatgaagat gaattggata
    27961 cacctccatt tttcaaaaat cgttaagtaa atgaatgtaa aagaaaatac agaacttgtt
    28021 tttcgagaag ttgcagaggc tagtctgagt gctcatcgag agagtggttc ggtctctgtc
    28081 attgcagtta ccaagtatgt agatgtaccg acagcggaag ccttgcttcc gctaggtgtt
    28141 catcatatcg gtgaaaatcg tgtagataag tttctggaaa aatatgaagc tttaaaagat
    28201 cgagatgtga cttggcattt gattggtacc ttgcaaagac gtaaggtgaa agatgtcatt
    28261 caatacgttg attatttcca tgcattggac tcagtaaagc tagcagggga aattcaaaaa
    28321 agaagtgacc gagtcatcaa gtgtttcctt caagtaaata tttctaaaga agaaagcaaa
    28381 cacggttttt cgagagagga actgctggaa atcttgccag agttagccag actagataag
    28441 attgaatatg ttggtttaat gacgatggca ccttttgagg ctagcagtga gcagttgaaa
    28501 gagattttca aggcggccca agatttacaa agagaaattc aagagaaaca aattccaaat
    28561 atgcctatga ccgagttaag tatgggaatg agtcgtgatt ataaagaagc gattcaattc
    28621 ggttccactt ttgttcgtat aggtacatca ttttttaagt aggagagaac catgtcttta
    28681 aaagatagat tcgatagatt tatagattat tttacggagg atgaggattc aagtctccct
    28741 tatgaaaaaa gagatgagcc tgtgtttact ccagtaaatt cttcacagga accggctctc
    28801 ccaatgaatc aaccttcaca gtcggctggt acaaaagaga acaatatcac cagacttcat
    28861 gcaagacaac aggaattggc aaatcagagt cagcgtgcaa cggataaggt cattatagat
    28921 gttcgttatc ctagaaaata tgaggatgca acagaaattg ttgatttatt ggcaggaaac
    28981 gaaagtatct tgattgattt tcagtatatg acagaggtgc aggctcgtcg ttgtttggac
    29041 tatttggatg gagcttgtca tgttttagct ggaaatttga aaaaggtagc ttctaccatg
    29101 tatttgttga caccagttaa tgttattgta aatgttgaag atatccgttt accagatgaa
    29161 gatcaacagg gtgagttcgg ttttgatatg aagcgaaata gagtacgata atgatttttt
    29221 taattcgtat gatttataat gcagtggata tttactccct gattttggta gccttcgctg
    29281 tcatgtcttg gtttccaggt gcctacgaat ccagtttagg tcgttggatt gtagcgttgg
    29341 tgaaaccagt acttgctccc ttgcaacgcc tgcctttaca gatagcgggt cttgatttat
    29401 ctgtttgggt cgcgattgtt ttggttcgat ttttaggaga aaacctagtg cgttttctgg
    29461 cgatgatagg atgaataaag ggatttatca gcatttctcc atagaagatc gtccatttct
    29521 tgacaaggga atggaatgga taaagaaggt agaagatagc tatgctcctt ttttaactcc
    29581 ttttatcaat cctcatcagg agaagctatt aaagattttg gccaaaacct atggtcttgc
    29641 ttgtagcagt agtggggaat tcgtctcgag tgagtatgtt cgagttttat tatacccaga
    29701 ttatttccaa ccagagtttt cagattttga aatatctctc caagaaattg tgtattccaa
    29761 taaatttgaa catttaacgc atgctaagat tttagggaca gtcatcaatc aattagggat
    29821 tgaacggaaa ctttttggag atatcctagt agatgaagaa cgggcgcaga ttatgattaa
    29881 tcagcagttt cttcttctct ttcaagatgg actaaagaaa attggtcgta tacctgtttc
    29941 gctggaggaa cgtcctttca ccgagaaaat agataagcta gaacagtatc gagaactgga
    30001 tttatctgtg tctagttttc gattagatgt tcttttatca aatgttttga aactatctag
    30061 gaatcaagca aaccagttga ttgaaaagaa acttgtccaa gtaaattatc atgtggtaga
    30121 caaatcagat tacactgttc aagttggaga cttgattagt gtgagaaaat ttggtcgctt
    30181 gagattactt caagataagg gacaaacgaa aaaagagaag aaaaaaataa ccgtccagtt
    30241 attattaagt aagtgaggaa tagaatgcca attacatcat tagaaataaa ggacaagact
    30301 tttggaactc gattcagagg ttttgatcca gaagaagtcg atgaattttt agatattgtg
    30361 gttcgtgatt acgaagatct tgtgcgtgcg aatcatgata aaaatttgcg tattaagagt
    30421 ttagaagagc gtttgtctta ctttgatgaa ataaaagatt cattgagcca gtctgtattg
    30481 attgctcagg atacagctga gagagtgaaa caggcggcgc atgaacgttc aaacaatatc
    30541 attcatcaag cagagcaaga tgcgcaacgc ttgttggaag aagctaaata taaggcaaac
    30601 gagattcttc gtcaagcaac tgataatgct aagaaagtcg ctgttgaaac agaagaattg
    30661 aagaacaaga gccgtgtctt ccaccaacgt ctcaaatcta caattgagag tcagttggct
    30721 attgttgaat cttcagattg ggaagatatt ctccgtccaa cagctactta tcttcaaact
    30781 agtgatgaag cctttaaaga agtggttagc gaagtacttg gagaaccgat tccagctcca
    30841 attgaagaag aaccaattga tatgacacgt cagttctctc aagcagaaat ggaagaatta
    30901 caagctcgta ttgaggtagc cgataaagaa ttgtctgaat ttgaagctca gattaaacag
    30961 gaagtggaaa ctccaactcc tgtagtgagt cctcaagttg aagaagagcc tctgctcatc
    31021 cagttggccc aatgtatgaa gaaccagaag tagctccagt gcatccgaca ggtccaacac
    31081 cagctacaga aactgttgat tcagcaccag gatttgaagc accgcaagaa tccgttacaa
    31141 ttttataaga aacgatgtga gaacaatatc ttatccttat atttccagcg agcaggagat
    31201 ggtgtgagtc ctgcattccc taacgataag attatcctct caaaaactca agtctgaagc
    31261 tagtaagatt tgacgtttcc cacgttacgg gataagaggg agaaagacta aatctttttc
    31321 cgaataaagg tggtaccacg attttcgtcc tttttggaag ttgtggtttt taatttgtta
    31381 ttatttataa aggagatacc atgaaactca aagataccct taatcttggg aaaacagctt
    31441 tcccaatgcg tgcaggcctt ccgaccaaag agccagtttg gcaaaaggaa tgggaagatg
    31501 caaaacttta ccaacgtcgt caagaactaa atgaagggaa accgcatttt gtcttgcatg
    31561 atggccctcc atacgcaaac ggaaatatcc acgttggaca tgccatgaat catatctcaa
    31621 aagatatcat cattcgttct aagtctatgt caggttttaa cgcaccttat atcccaggtt
    31681 gggatactca tggtctgcca atcgagcaag ttttggcaaa gcaaggtgtg aagcgcaaag
    31741 aaatggactt ggttgagtac ttgaaactct gtcgtgagta cgctctttct caagtttata
    31801 aacaacgtga tgatttcaaa cgcttgggga tgtcaggtga ctgggaaaat ttatatgtga
    31861 ctttaactcc agactatgaa gcagcccaaa tccgtgtctt tggtgagatg gctaataagg
    31921 gttatatcta ccgtggtgcc aagccagttt actggtcatg gtcatctgag tcagcccttg
    31981 ccgaagcgga aattgaatac catgatttgg tttcgacttc actttattat gccaataagg
    32041 taaaagatgg caaaggtatc ctagatacag atacttatat cgtagtctgg acaacaactc
    32101 catttaccat cacagcttct cgtggtttga ctgttggtgc agatattgat tacgttttgg
    32161 ttcaacctgc tagtgaaact cgtaagtttg tcgttgctgc agaattgttg actagcttgt
    32221 ctgagaaatt tggctgggct gatgttcaag tgttggcaac ttaccgtggt caagaactca
    32281 accacatcgt aacagaacac ccatgggata cagctgtaga tgagttggta atccttggtg
    32341 atcacgttac cactgactct ggtacaggta tcgtccatac agcccctggt tttggtgagg
    32401 acgactacaa tgttggtatt gctaatggtc ttgaagtcgc agtgactgtt gacgaacgcg
    32461 gtatcatgat ggcgaatgct ggtcctgagt ttgaaggtca gttctacgac aaggttgtac
    32521 caactgttat tgaaaaactt ggtaacctcc ttctagccca agaagaaatc tctcactcat
    32581 acccatttga ctggcgtact aagaaaccaa tcatctggcg tgcagttcca caatggtttg
    32641 cctcagtttc aaaattccgc caagaaatct tggatgctat tgataaagtt aaattccata
    32701 cagaatgggg taaagtacgt ctatataata tgattcgtga ccgtggtgac tgggttatct
    32761 ctcgtcaacg tgcttggggt gttccacttc caatcttcta tgcagaagac ggtacagcta
    32821 tcatgacagc tgagactatt gaacatgtgg cgcaactctt tgaagtacat ggttcaagca
    32881 tttggtggga acgtgatgcc aaagacctct taccagaagg atttacacat ccaggttctc
    32941 caaatgggga gttcaagaaa gaaacagata ttatggatgt atggtttgac tcaggttcat
    33001 catggaatgg tgttttggta aatcgtccaa atctgactta tccagctgac ctttaccttg
    33061 aaggttctga ccaataccgt ggttggttca actcatcact cattacatct gttgccaacc
    33121 atggcgtagc accttacaaa caaatcttgt cacaaggttt tacccttgat ggtaaaggtg
    33181 agaagatgtc taaatcactt ggaaatacca ttgctccaag tgatgttgaa aaacaatttg
    33241 gtgcagaaat cttgcgtctc tgggtaacaa gtgttgactc aagcaatgac gtgcgtatct
    33301 ctatggatat tttgagccaa gtttctgaaa cttaccgtaa gattcgtaac actcttcgtt
    33361 tcttgattgc caatacatct gactttaacc cagctcaaga tgtagtcgct tacgatgaac
    33421 ttcgttcagt tgataagtac atgactattc gctttaacca gcttgtcaag accattcgtg
    33481 atgcctatgc ggactttgaa ttcttgacaa tctacaaggc cttggtgaac tttatcaacg
    33541 ttgacttgtc agccttctac cttgattttg ccaaagatgt tgtttacatt gaaggtgcca
    33601 aatcattgga acgccgtcaa atgcagactg ttttctatga cattcttgtc aaaatcacca
    33661 aactcttgac accaatcctt cctcacactg cggaagaaat ctggtcatat cttgagtttg
    33721 aagctgaaga cttcgttcaa ttgtcagaat tgccagaagc tcaaactttt gctaatcaag
    33781 aagaagtctt ggatacatgg gcagccttca tggacttccg tggacaagct caaaaagcct
    33841 tggaagaagc tcgtaatgca aaagttatcg ggaaatcgct tgaagcacac ttgacagttt
    33901 atccaaatga agttgtgaaa actctactcg aagcagtaaa cagcaatgtg gctcaacttt
    33961 tgatcgtgtc agacttgacc atcgcagaag ggccagctcc agaagctgcc cttagcttcg
    34021 aagatgtagc cttcacagtt gaacgcgctg caggtgaagt atgtgaccgt tgccgtcgta
    34081 ttgacccaac aacagcagaa cgtagctacc aggcagttat ctgtgaccac tgtgcaagta
    34141 tcgtagaaga aaactttgca gatgcagtcg cagaaggatt tgaagagaaa taagattgaa
    34201 aagtctaggc aaaattcaat ttgagaagaa aagacaacta attttatagt ctattaaacg
    34261 cattgtatca cgtttttgaa cacctgatat gatgcgtttt ttatttttaa aatttgcaag
    34321 gtgtgacttt ttatactcat actcaatgaa aatcaaaaag caaactagga agctagccgc
    34381 aggctgctca aaacactgtt ttgaggttgt agataagact gacgaagtca gtaacatata
    34441 tatggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtatca acaagaatca
    34501 aagagaaact tagcaagcta acagtagtaa gataaaatag gaatttgata ttagggataa
    34561 gattggtaaa tagtgtaata tttttacaac aataaattta tatagttatt tctggttt
//
LOCUS       DAVLIK010000020        33180 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLIK010000020 DAVLIK010000000
VERSION     DAVLIK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.020"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..1095
                     /gene="lytB"
                     /locus_tag="VXE87_001063"
     CDS             <1..1095
                     /gene="lytB"
                     /locus_tag="VXE87_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0842621.1"
                     /translation="KEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAE
                     KEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTA
                     NVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFI
                     PYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLT
                     EATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRS
                     KIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASG
                     MNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1156..2811)
                     /gene="pavA"
                     /locus_tag="VXE87_001064"
     CDS             complement(1156..2811)
                     /gene="pavA"
                     /locus_tag="VXE87_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0842622.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2916..3413
                     /gene="ybeY"
                     /locus_tag="VXE87_001065"
     CDS             2916..3413
                     /gene="ybeY"
                     /locus_tag="VXE87_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0842623.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRNTDRPTDVISLEYKPELEIAFDEEDLLENSELAEMMSEFDAYIGEL
                     FISSDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3394..3789
                     /locus_tag="VXE87_001066"
     CDS             3394..3789
                     /locus_tag="VXE87_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0842624.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3806..4705
                     /gene="era"
                     /locus_tag="VXE87_001067"
     CDS             3806..4705
                     /gene="era"
                     /locus_tag="VXE87_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0842625.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4754..5578
                     /gene="mutM"
                     /locus_tag="VXE87_001068"
     CDS             4754..5578
                     /gene="mutM"
                     /locus_tag="VXE87_001068"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0842626.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLNQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5578..6183
                     /locus_tag="VXE87_001069"
     CDS             5578..6183
                     /locus_tag="VXE87_001069"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0842627.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6170..7369
                     /locus_tag="VXE87_001070"
     CDS             6170..7369
                     /locus_tag="VXE87_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV0842628.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7369..7518
                     /gene="rpmG"
                     /locus_tag="VXE87_001071"
     CDS             7369..7518
                     /gene="rpmG"
                     /locus_tag="VXE87_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0842629.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7558..7791
                     /gene="secG"
                     /locus_tag="VXE87_001072"
     CDS             7558..7791
                     /gene="secG"
                     /locus_tag="VXE87_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0842630.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7893..10247
                     /gene="rnr"
                     /locus_tag="VXE87_001073"
     CDS             7893..10247
                     /gene="rnr"
                     /locus_tag="VXE87_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0842631.1"
                     /translation="MKDRIKEYLQDKGKMTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVLSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10210..10677
                     /gene="smpB"
                     /locus_tag="VXE87_001074"
     CDS             10210..10677
                     /gene="smpB"
                     /locus_tag="VXE87_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0842632.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10693..11553
                     /gene="tehB"
                     /locus_tag="VXE87_001075"
     CDS             10693..11553
                     /gene="tehB"
                     /locus_tag="VXE87_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0842633.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11626..12579
                     /gene="coiA"
                     /locus_tag="VXE87_001076"
     CDS             11626..12579
                     /gene="coiA"
                     /locus_tag="VXE87_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0842634.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHIANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12598..14400
                     /gene="pepF"
                     /locus_tag="VXE87_001077"
     CDS             12598..14400
                     /gene="pepF"
                     /locus_tag="VXE87_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0842635.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENRGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTIFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14402..15115
                     /locus_tag="VXE87_001078"
     CDS             14402..15115
                     /locus_tag="VXE87_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0842636.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFIMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15182..16123
                     /gene="prsA"
                     /locus_tag="VXE87_001079"
     CDS             15182..16123
                     /gene="prsA"
                     /locus_tag="VXE87_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0842637.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16242..16583)
                     /locus_tag="VXE87_001080"
                     /pseudo
     CDS             complement(16242..16583)
                     /locus_tag="VXE87_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            16995..17090
                     /locus_tag="VXE87_001081"
                     /pseudo
     CDS             16995..17090
                     /locus_tag="VXE87_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17343..17963)
                     /locus_tag="VXE87_001082"
     CDS             complement(17343..17963)
                     /locus_tag="VXE87_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0842638.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(17963..18445)
                     /locus_tag="VXE87_001083"
     CDS             complement(17963..18445)
                     /locus_tag="VXE87_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0842639.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(18445..19287)
                     /locus_tag="VXE87_001084"
     CDS             complement(18445..19287)
                     /locus_tag="VXE87_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0842640.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(19382..20170)
                     /locus_tag="VXE87_001085"
     CDS             complement(19382..20170)
                     /locus_tag="VXE87_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0842641.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQALK
                     HLDKPIIDLSGWQHPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDKAYKS
                     HITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTMSNMN
                     EGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLESSPKT
                     DLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            20323..21702
                     /gene="glmU"
                     /locus_tag="VXE87_001086"
     CDS             20323..21702
                     /gene="glmU"
                     /locus_tag="VXE87_001086"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0842642.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            21712..22257
                     /locus_tag="VXE87_001087"
     CDS             21712..22257
                     /locus_tag="VXE87_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0842643.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDENETLEVLEVSLEEAKELIQ
                     SGRICDAKTIMAVQYWELQKK"
     gene            22269..22583
                     /locus_tag="VXE87_001088"
     CDS             22269..22583
                     /locus_tag="VXE87_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0842644.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            22600..23292
                     /locus_tag="VXE87_001089"
     CDS             22600..23292
                     /locus_tag="VXE87_001089"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0842645.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            23369..23860
                     /gene="rocS"
                     /locus_tag="VXE87_001090"
     CDS             23369..23860
                     /gene="rocS"
                     /locus_tag="VXE87_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0842646.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            23958..24548
                     /locus_tag="VXE87_001091"
     CDS             23958..24548
                     /locus_tag="VXE87_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0842647.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQASAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            24557..26320
                     /locus_tag="VXE87_001092"
     CDS             24557..26320
                     /locus_tag="VXE87_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0842648.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            26534..27170
                     /locus_tag="VXE87_001093"
                     /pseudo
     CDS             26534..27170
                     /locus_tag="VXE87_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            27343..27543
                     /locus_tag="VXE87_001094"
     CDS             27343..27543
                     /locus_tag="VXE87_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842649.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            27568..27984
                     /locus_tag="VXE87_001095"
     CDS             27568..27984
                     /locus_tag="VXE87_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842650.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGMEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            28215..28922
                     /gene="ccdA2"
                     /locus_tag="VXE87_001096"
     CDS             28215..28922
                     /gene="ccdA2"
                     /locus_tag="VXE87_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0842651.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            28933..29490
                     /gene="sdbB"
                     /locus_tag="VXE87_001097"
     CDS             28933..29490
                     /gene="sdbB"
                     /locus_tag="VXE87_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0842652.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGQEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            29864..31255
                     /locus_tag="VXE87_001098"
     CDS             29864..31255
                     /locus_tag="VXE87_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0842653.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            31398..32315
                     /gene="adcAII"
                     /locus_tag="VXE87_001099"
     CDS             31398..32315
                     /gene="adcAII"
                     /locus_tag="VXE87_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0842654.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            32323..>33180
                     /gene="phtD"
                     /locus_tag="VXE87_001100"
     CDS             32323..>33180
                     /gene="phtD"
                     /locus_tag="VXE87_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0842655.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLS"
BASE COUNT        10153 a         6016 c         7197 g         9814 t
ORIGIN      
        1 aaagaatggg tctacgattc tcatagtcaa gcttggtact acttcaaatc cggtggttac
       61 atgacagcca atgaatggat ttgggataag gaatcttggt tttacctcaa gtctgatggc
      121 aaaatggctg aaaaagaatg ggtctacgat tctcatagtc aagcctggta ctacttcaaa
      181 tctggtggct acatggcgaa aaatgagaca gtagatggtt atcagcttgg aagcgatggt
      241 aaatggcttg gaggaaaagc tacaaatgaa aatgctgctt actatcaagt agtgcctgtt
      301 acagccaatg tttatgattc agatggtgaa aagctttcct atatatcgca aggcagtgtc
      361 gtatggctag ataaggatag aaaaagtgat gacaagcgct tggctattac tatttctggt
      421 ttgtcaggct atatgaaaac agaagattta caagcgctag atgctagtaa ggactttatc
      481 ccttattatg agagtgatgg ccaccgtttt tatcactatg tggctcagaa tgctagtatc
      541 ccagtagctt ctcatctttc tgatatggaa gtaggcaaga aatattattc ggcagatggc
      601 ctgcattttg atggttttaa gcttgagaat cccttccttt tcaaagattt aacagaggct
      661 acaaactaca gtgctgaaga attggataag gtatttagtt tgctaaacat taacaatagc
      721 cttttggaga acaagggcgc tacttttaag gaagccgaag aacattacca tatcaatgct
      781 ctttatctcc ttgcccatag tgccctagaa agtaactggg gaagaagtaa aattgccaaa
      841 gataagaata atttctttgg cattacagcc tatgatacga ccccttacct ttctgctaag
      901 acatttgatg atgtggataa gggaatttta ggtgcaacca agtggattaa ggaaaattat
      961 atcgataggg gaagaacttt ccttggaaac aaggcttctg gtatgaatgt ggaatatgct
     1021 tcagaccctt attggggcga aaaaattgct agtgtgatga tgaaaatcaa tgagaagcta
     1081 ggtggcaaag attagtacta taagtgaata tgatttgagt gaatagtaag ttaaaaatcc
     1141 tgatttcaag taaaatcagg attttttcat ggatgcaatt tttttggagt ctggtgtgac
     1201 gcggagggtc ttttgtcctg tgtaagtgac aaagccgggt tttccaccag ttggtttatt
     1261 gagttttttg acttcaatca tatctacctg caccagattc gacaggcgcc cttgagagaa
     1321 gtaggcagct aactctgctg cgtctgtctt gactgcatca gatgggtcaa gatttcctga
     1381 gatgacaaca tggcttccag gaatgtcctt agcatggaac caaagttcct ccttgcgggc
     1441 cattttaaag gtcaattcct cattttgaag attgtttcgt ccgacataga tgatggtttt
     1501 gccatcgctt gctagatatt gttctagttt tttgcgtttc tggattttct cccgttgtct
     1561 tctgcggata aaacctgttt gaatcaattc ttcacggatt tcagcgattt cttccagtcc
     1621 agcttggttg aggacggttt ctacactttc cagatagaga atagtggctt tggtttcttc
     1681 aatcaaatca gtcaagtatt tgacagcttc tttgagtttc tgataccgtt taaaatagcg
     1741 ttgggcattc tggttgggag tcagagcctt atcaagcgca atcatgatag gttggttggt
     1801 atagtagttg tctaggataa cctggtcttg gtcgttaggc acttggtgta ggaaggttgt
     1861 cagcaattct cctttttgac gaaattcttc agcgttgtct gtcgccagta actctttttc
     1921 ctgttttttg agtttgtgtc ggtttttctg aagttcattt tcaacacgac gaatcagttc
     1981 actggcctgc tgtttgacgc ggtcgcgctc agccttatcc ttatagtagg tgtccaacaa
     2041 atcagaaaga tttgcaaaag gctctcccac ctgatttgca aaaggaactg gactgaagga
     2101 agtctcagtc aagcatggct tggtttcttg attgaaaaaa tttcggaaag cggaaagttt
     2161 ttcactaacc agtatccttt ccaattcatt tgccgtatcg cgtcccagac cttgaaagag
     2221 gctttgaaga ttttttgctg ttagttcttg ggtttgcagg atttcaaaga gcttttcatc
     2281 cttgatagta aaaggattga gagattctgt acttggcgga gcgatatagg tcgatcctgg
     2341 aagtaaggtg cggtagctat tttgtgaaaa accgacgtgt ttgataactt cgaggatttt
     2401 atgactgctt ttatcgacca gtagaatatt actgtgtttc cccataattt cgataatcaa
     2461 ggtagcctgg atatggtctc caatctcgtt tttattggaa actgtaattt ccacaatacg
     2521 gtcattttcc acttgctcaa tcgactcaat cagggccccc tgcaaatact ttctcaaaac
     2581 catgataaag gtagaaggtt gagctggatt ttcaaaagtc gtttgggtca gctgaatgcg
     2641 tccaaaaact ggatgggcag aaaggagcag gcgatggctt tggcgattgc tgcggatttg
     2701 caagaccaac tcttgttcaa aaggctgatt gattttctgg atgcgaccat tcactaattc
     2761 gcttcgcaat tcctcaacta tgtggtgtaa aaaaaatccg tcaaatgaca tcgttctctc
     2821 cttgtgattg tattccatag tattatatca aaaaggtaga ataaaatcat ggaaatgtgg
     2881 tataataaag ccaagtaaag agaaacgaga agcacatgta tattgaaatg gtagatgaaa
     2941 ctggtcaagt ttcaaaagaa atgttgcaac aaacccaaga aattttggaa tttgcagccc
     3001 aaaaattagg aaaagaagac aaggagatgg cagtcacttt tgtgaccaat gagcgtagtc
     3061 atgaacttaa tctggagtac cgtaacaccg accgtccgac agatgtcatc agccttgagt
     3121 ataaaccaga attggaaatt gcctttgacg aagaggattt gcttgaaaat tcagaattgg
     3181 cagagatgat gtctgagttt gatgcctata ttggggaatt gttcatctct agcgataagg
     3241 ctcatgagca ggccgaagaa tatggtcaca gctttgagcg tgagatgggc ttcttggcag
     3301 tacacggctt tttacatatt aacggctatg atcactacac tccggaagaa gaagcggaga
     3361 tgttcggttt acaagaagaa attttgacag cctatggact cacaagacaa taaacgaaaa
     3421 tggaaaaatc gtgacctgat atccagttta gaatttgcca tcacagggat ttttactgct
     3481 atcaaggaag aacgaaatat gcgaaaacat gcagtgacgg ctctagtggt catccttgca
     3541 ggttttgttt ttcaggtgtc acgaatcgaa tggctctttc tcctattgag cattttcttg
     3601 gtagtagcct ttgagattat caactctgct attgaaaata tggtggattt ggccagtcac
     3661 tatcactttt ccatgctggc taaaaatgcc aaggatatgg cggctggcgc ggtattagtg
     3721 gtttctcttt tcgcagcctt aacaggtgca ttgatttttc tcccacgaat ctgggattta
     3781 ttattttaaa cagtaagagg aaattatgac ttttaaatca ggctttgtag ccattttagg
     3841 acgtcccaat gttgggaagt caaccttttt aaatcacgtt atggggcaaa agattgccat
     3901 catgagtgac aaggcgcaga caacgcgcaa taaaatcatg ggaatttaca cgactgataa
     3961 ggagcaaatt gtctttatcg acacaccagg gattcacaaa cctaaaacag ctctcggaga
     4021 tttcatggtt gagtctgcct acagtaccct tcgcgaagtg gacaccgttc ttttcatggt
     4081 gcctgctgat gaagcgcgtg gtaaggggga cgatatgatt atcgagcgtc tcaaggctgc
     4141 caaggttcct gtgattttgg tggtgaataa aatcgataag gtccatccag accagctctt
     4201 gtctcagatt gatgacttcc gtaatcaaat ggactttaag gaaattgttc caatctcagc
     4261 ccttcaggga aataacgtgt ctcgtctagt ggatattttg agtgaaaatc tggatgaagg
     4321 tttccaatat ttcccgtctg atcaaatcac agatcatcca gaacgtttct tagtttcaga
     4381 aatggttcgc gagaaagtct tgcacctaac tcgtgaagag attccgcatt ctgtagcagt
     4441 agttgttgac tctatgaaac gagacgaaga gacagacaag gttcacatcc gtgcaaccat
     4501 catggtcgag cgcgatagcc aaaaagggat tatcatcggt aaaggtggcg ctatgcttaa
     4561 gaaaatcggt agtatggccc gtcgtgatat cgaactcatg ctaggagaca aggtcttcct
     4621 agaaacctgg gtcaaggtca agaaaaactg gcgcgataaa aagctagatt tggctgactt
     4681 tggctataat gaaagagaat actaagtaga ggtaggctca tgcctgcttc ttgtttttac
     4741 agaaggagga cttatgcctg aattacctga ggttgaaacc gtttgtcgtg gcttagaaaa
     4801 attgattata ggaaagaaga tttcgagtat agaaattcgc taccccaaga tgattaagac
     4861 ggatttggaa gagtttcaaa gggaattgcc tagtcagatt atcgagtcaa tgggacgtcg
     4921 tggaaaatat ttgctttttt atctgacaga caaggtcttg atttcccatt tgcggatgga
     4981 gggcaagtat ttttactatc cagaccaagg acctgaacgc aagcatgccc atgttttctt
     5041 tcattttgaa gatggtggca cgcttgttta tgaggatgtt cgcaagtttg gaaccatgga
     5101 actcttggtg cctgaccttt tagacgccta ctttatttct aaaaaattag gtcctgaacc
     5161 aagcgaacaa gactttgatt tacaggtctt tcaatctgcc cttgccaagt ccaaaaagcc
     5221 tatcaaatcc catctcctag accagacctt ggtagctgga cttggcaata tctatgtgga
     5281 tgaggttctc tggcgagctc aggttcatcc agctagatct tcccagactt tgacagcaga
     5341 agaagcgaca gctattcatg accaaaccat tgctgttttg aaccaggctg ttgaaaaagg
     5401 cggttccacc attcggacct ataccaatgc ctttggggaa gatggaagca tgcaggattt
     5461 tcatcaggtc tatgataaga ctggtcaaga atgtgtacgc tgtggtacca tcattgagaa
     5521 aattcaacta ggcggacgag gcacccactt ttgtccaaac tgtcaaagga gggactgatg
     5581 agaaaaatca tcggaatcac tgggggaatt gcctctggta agtcaactgt gacaaatttt
     5641 ctaagacagc aaggctttca agcagtggat gccgacgcag tcgtccacca actacagaaa
     5701 cctggtggtc gtctgtttga ggctctagta cagcactttg ggcaagaaat cattcttgaa
     5761 aacggagaac tcaatcgccc tctcctagct agtctcatct tttcaaatcc tgaagagcaa
     5821 aaatggtcta agcaaattca aggggagatt atccgtgagg aactggctac tttgagagaa
     5881 cagttggctc agacagaaga gattttcttc atggatattc ccctactttt tgagcaggac
     5941 tacagcgatt ggtttgctga gacttggttg gtctatgtgg accgagatac ccaagtagaa
     6001 cgcttaatga aaagggacca gttgtccaag gatgaagctg agtctcgtct ggcagcccag
     6061 tggcctttag aaaaaaagaa agatttggcc agccaggttc ttgataataa tggcaatcag
     6121 aaccagcttc ttaatcaagt gcatatcctt cttgagggag gtaggcaaga tgacagagat
     6181 taactggaag gataatctgc gcattgcctg gtttggtaat tttctgacag gagccagtat
     6241 ttctttggtt gtacctttta tgcccatctt cgtggaaaat ctaggtgtag ggagtgagca
     6301 agtcgctttt tatgcaggct tagcaatttc tgtctctgct atttccgcgg cgctcttttc
     6361 tcctatttgg ggtattcttg ctgacaaata cggccgaaaa cccatgatga ttcgggcagg
     6421 tcttgctatg actatcacta tgggaggctt ggcctttgtc ccaaatatct attggttaat
     6481 ctttcttcgt ttactaaacg gtgtatttgc aggttttgtt cctaatgcaa cggcactgat
     6541 agccagtcag gttccaaagg agaaatcagg ctctgcctta ggtactttgt ctacaggcgt
     6601 agttgcaggt actctaactg gtccctttat tggtggcttt atcgcagaat tatttggcat
     6661 tcgtacagtt ttcttactgg ttggtagttt tctattttta gctgctattt tgactatttg
     6721 ctttatcaag gaagattttc aaccagtagc caaggaaaag gctattccaa caaaggaatt
     6781 atttacctcg gttaaatatc cctatctttt gctcaatctc tttttaacca gttttgtcat
     6841 ccaattttca gctcaatcga ttggccctat tttggctctt tatgtacgcg acttagggca
     6901 gacagagaat cttctttttg tctctggttt gattgtgtcc agtatgggct tttccagcat
     6961 gatgagtgca ggagtcatgg gcaagctagg tgacaaggtg ggcaatcatc gtctcttggt
     7021 tgtcgcccag ttttattcag tcatcatcta tctcctctgt gccaatgcct ctagccccct
     7081 tcaactagga ctctatcgtt tcctctttgg attgggaacc ggtgccttga ttcccggggt
     7141 taatgcccta ctcagcaaaa tgactcccaa agccggcatt tcgagggtct ttgccttcaa
     7201 tcaggtattc ttttatctgg gaggtgttgt tggtcccatg gcaggttctg cagtagcagg
     7261 tcaatttggc taccatgctg tcttttatgc gacgagcctt tgtgttgcct ttagttgtct
     7321 ctttaacctg attcaatttc gaacattatt aaaagtaaag gaaatctagt gcgagtaaaa
     7381 attaatctca aatgctcctc ttgtgacagt atcaattacc taaccagtaa aaattcaaaa
     7441 acccatccag acaagattga ggttttaaag tattgtccca aggaaagaaa agtaacccta
     7501 catcttgaat ctaagtagat tttatggtaa aataataggg attttaagga gtttgatatg
     7561 tataacctat tattaaccat tttattagta ttatctgttg tgattgtgat tgcaattttc
     7621 atgcaaccaa ccaaaaacca atccagcaat gtatttgatg ccagttcagg tgatttgttt
     7681 gaacgcagta aagctcgcgg ttttgaagct gtaatgcagc gtttgacagg gattttagtc
     7741 tttttctggc tagccattgc cttagcattg acggtattat caagtagata agaaaataat
     7801 gggcaggact aggtctttgc ctctttttat ttttaaagga tgtttgagaa ggttttacag
     7861 taaaagaaaa ttaaaaaatc tagaaagaaa atatgaaaga tagaataaaa gaatatttac
     7921 aagacaaggg aaagatgact gttaatgatt tggctcaggc tttgggaaaa gacagttcca
     7981 aggattttcg tgagttgatt aaaaccttgt ccttaatgga aagaaagcac caaattcgtt
     8041 ttgaagaaga tggtagtctg acattagaaa ttaagaaaaa acatgagatt accctcaagg
     8101 ggatttttca tgcccataaa aatggctttg gctttgttag tctggaaggc gaggaggacg
     8161 acctttttgt agggaaaaat gatgtcaact atgctattga tggtgatacc gtcgaggtag
     8221 tgattaagaa agtcgctgac cgcaataagg gaacagcagc agaagccaaa attattgata
     8281 tcctagaaca cagtttgaca acagttgtcg ggcaaatcgt tctggatcag gaaaagccta
     8341 agtatgctgg ctatattcgt tcaaaaaatc agaaaatcag tcaaccgatt tatgttaaga
     8401 aaccagccct aaagttagaa ggaacagaag ttctcaaggt ctttatcgat aaatacccaa
     8461 gcaagaaaca tgatttcttt gtcgcgagtg ttctcgatgt agtgggacac tcaacggatg
     8521 tcggaattga tgttcttgag gtcttggaat caatggacat tgtatccgag tttccagaag
     8581 ctgttgttaa ggaagcagaa agtgtgcctg atgctccgtc tcaaaaggat atggaaggtc
     8641 gtctggatct aagagatgaa attaccttta ccattgacgg tgcggatgcc aaggacttgg
     8701 acgatgcagt gcatatcaag gctctgaaaa atggcaatct ggagcttggg gttcacatcg
     8761 cagatgtttc ttattatgtg accgaggggt ctgcccttga caaggaagcc cttaaccgtg
     8821 cgacttctgt ttacgtgaca gaccgagtgg tgccaatgct tccagaacga ctatcaaatg
     8881 gcatctgctc tctcaatccc caagttgacc gcctgaccca gtctgctatt atggagattg
     8941 ataaacatgg tcgtgtggtc aactatacca ttacacaaac agttatcaag accagttttc
     9001 gtatgaccta tagcgatgtc aatgatatcc tagctggcga tgaagaaaag agaaaagaat
     9061 atcataaaat tgtattaagt atcgaactca tggccaagct tcatgaaact ttagaaaaca
     9121 tgcgtgtgaa acgtggagct ctcaattttg ataccaatga agcgaagatt ttagtggata
     9181 aacaaggtaa gcctgttgat atcgttcttc ggcagcgtgg tattgccgag cggatgattg
     9241 agtcttttat gttgatggct aatgaaacag ttgccgaaca tttcagcaag ttggatttgc
     9301 cttttatcta tcgaattcac gaggagccta aggctgaaaa ggttcagaag tttattgatt
     9361 atgcttcgag ttttggcttg cgcatttatg gaactgccag tgagattagt caggaggcac
     9421 ttcaagacat catgcgtgct gttgagggag aaccttatgc agatgtattg tccatgatgc
     9481 ttcttcgctc tatgcagcag gctcgttatt cggagcacaa tcacggccac tatggactag
     9541 ctgctgacta ttatactcac tttaccagtc caattcgtcg ttatccagac cttcttgttc
     9601 accgtatgat tcgagattac ggctgttcta aggaaatagc agagcatttt gaacaagtga
     9661 ttccagagat tgcgacccag tcttccaacc gtgaacgtcg tgccatagaa gctgagcgtg
     9721 aagtcgaagc catgaaaaag gctgagtata tggaagaata cgtgggtgaa gagtatgatg
     9781 cagttgtatc aagtattgtc aaattcggtc tctttgtcga attgccaaac acagttgaag
     9841 gcttgattca catcactaat ctacctgaat tttatcattt caatgagcgt gatttgactc
     9901 ttcgtggaga aaaatcaggt atcactttcc gagtgggtca gcagatccgt atccgtgttg
     9961 aaagagcgga taaaatgact ggagagattg atttttcatt cgtacctagt gagtttgatg
    10021 tgattgaaaa aggcttgaaa cagtctagtc gtagtggcag aggtcgtggt tcaaatcgtc
    10081 gttcggataa gaaggaagac aagagaaaat taggacgctc aaatgataag cgtaagcatt
    10141 cacaaaaaga caagaagaaa aaaggaaaga aaccttttta caaggaagta gctaagaaag
    10201 gagccaagca tggcaaaggg cgagggaaag gtcgtcgcac aaaataaaaa ggcacgccac
    10261 gactatacaa tcgtagatac gctagaggca gggatggtcc tgactggaac tgaaatcaag
    10321 agtgtacgag ctgctcgaat taatctcaag gatggctttg ctcaagtgaa aaatggagaa
    10381 gtttggctga gcaatgttca tatcgcgcct tacgaagagg gcaatatctg gaaccaggaa
    10441 ccagaacgtc gtcgtaaact cctgcttcat aaaaagcaaa ttcaaaaatt ggaacaagag
    10501 accaaaggga caggaatgac cttagttccc cttaaggtct atataaaaga tggctacgct
    10561 aagcttcttt taggacttgc caaagggaag catgactatg acaaacggga gtctatcaaa
    10621 cgtcgtgagc aaaatcgaga tatcgcgcgt gtgatgaaag ctgttaatca gcgataaaaa
    10681 gaggaattga aaatggaaaa attagttgcc tataaacgca tgcctttgtg gaataaacaa
    10741 acaatgcctg aagctgttca gcaaaagcac aatacaaaag ttgggacttg ggggaaaatt
    10801 actgtcttga agggagctct caagtttatt gaattgacag aagaagggga agttctagct
    10861 gaacacctct ttgaagcagg ggcagacaat ccaatggccc aacctcaagc ctggcaccga
    10921 gtggaagctg ccacagatga tgtggaatgg tacttggaat tttattgtaa acctgaggat
    10981 tattttgcta aaaaatacaa taccaatcct gttcattcag aggtcctaga ggccatgcag
    11041 acagtgaaac aagggaaagc tttggatttg ggttgtggtc aggggcgtaa ttctcttttt
    11101 ctagcccagc aagattttga tgtgacggct gtagatcaaa atggactagc tcttgaaatc
    11161 ttgcaaagca ttgtggagca ggaagatttg gacatgcctg ttggccttta cgatatcaat
    11221 tcagctagca ttgaacaaga atatgatttt atcgtttcaa cagttgttct catgtttcta
    11281 caagcggacc gcattccagc tattattcaa aatatgcagg agaaaaccag tgttggtggt
    11341 tacaacctta tcgtttgtgc catggacacg gaggattatc cttgctcggt taacttccca
    11401 ttcaccttta aagaaggaga actggcagac tattacaagg attgggaatt ggttaagtac
    11461 aatgaaaatc caggccattt gcaccgtcgc gatgagaatg gcaatcgtat tcaactacgc
    11521 tttgcgacct tactagctaa gaaaatcaag taaacacaca tgaagattag gaattttcct
    11581 gatctttttt cttttttacg aatgatatag aaaaggaggg aattcatgtt tgttgcgaga
    11641 gatgctaggg gagaattggt aaatgtgtta gaggataaac ttgagaagca agcatacacc
    11701 tgcccagctt gtggaggcca gatccatttg cgtcaaggac caagtgtacg gacgcatttt
    11761 gcccataaat ccttaaaaga ctgtgatttt ttctttgaaa atgaaagtcc agaacacata
    11821 gccaataagg aatccctcta tcactggttg aaaaaagaga caaaggttca attagagtac
    11881 ccgctttcag aacttaaaca gattgcggat gtatttgtaa atggcaatct agctctagaa
    11941 gttcagtgta gtcccttgcc tcagaaagtc cttaaagagc gaagtgaggg ctatcgtagt
    12001 cagggttacc aagtactgtg gttgctgggt caaaaactgt ggctcaagga gcgtttgact
    12061 cgtctacagc aaggttttct ttatttcagt caaaacatgg gcttttatgt ttgggaatta
    12121 gacaaggaaa aacaagtttt aagactcaaa tacctgattt accaggatct ccgcggtaaa
    12181 ctccattatc aaatcaagga attttcctat ggtcaaggta gtttattgga aatattgcgt
    12241 cttccctata agagacaaaa aatatctcat tttacagttt ctgaggacaa ggacatctgt
    12301 cgctatatcc ggcaacaact ttattatcaa aatctctttt ggatgaaaga acaagcagaa
    12361 gcctatcaaa agggagaaaa tatcctgact tatggactga aagaatggta tccacaaatt
    12421 cgaccaatag tgggcaaatt tttccagatt gaacaagact tgactagcta ttatcagcac
    12481 ttttatacct attaccaaaa aaatcctcaa aatgattggc aaaagcttta tccaccagcc
    12541 ttttatcagc aatatttctt gaaaaatatg gtagaataga aaggatggag gaatctaatg
    12601 gtattacaaa gaaatgaaat aaatgaaaaa gatacatggg atctatcaac gatctaccca
    12661 actgaccagg cttgggaaga agccttaaaa gatttaacag aacaattgga gacagtagcc
    12721 cagtatgaag gccatctctt ggatagtgcg gataacctac tagaaatcac tgaattttct
    12781 cttgaaatgg aacgccagat agagaagctt tacgtttatg ctcatatgaa gaatgaccag
    12841 gatacacgtg aagctaagta tcaagagtac tatgccaagg ccatgacact ctacagccag
    12901 ttagaccaag ccttttcatt ctatgagcct gaatttatgg agattagcga aaagcagtat
    12961 gctgactttt tagaagctca accaaagctg caggtttatc aacactattt tgacaagctc
    13021 ttgcaaggca aggatcacgt tctttcacaa cgtgaagaag aattattggc tggagctgga
    13081 gaaatctttg gttcagcaag tgaaaccttc gctatcttgg acaatgcgga tattgtgttc
    13141 ccttatgtcc tagacgatga tggtaaagaa gttcagctat ctcatgggac ttacacacgt
    13201 ttgatggagt ctaaaaaacg tgaggttcgc cgtggtgcct atcaagctct ttatgcgact
    13261 tacgaacaat tccaacacac ctatgccaaa accttgcaaa ccaatgttaa ggtgcaaaat
    13321 taccgtgcta aagttcgtaa ctacaagagt gctcgtcatg cagccctcgc agcgaatttt
    13381 gttccagaaa gtgtttatga caatttggta gcagcagttc gcaagcattt gccactctta
    13441 catcgctatc ttgagcttcg ttcaaaaatc ttggggattt cagatctcaa gatgtacgat
    13501 gtctacacac cgctttcatc tgttgaatac agttttacct accaagaagc cttgaaaaaa
    13561 gcagaagatg ctttggcagt cttgggtgag gattacttga gccgtgttaa acgtgccttc
    13621 agcgagcgtt ggattgatgt ttacgaaaat cgaggcaagc gttcaggtgc ctactctggt
    13681 ggttcttacg ataccaatgc ctttatgctt ctcaactggc aggacaatct ggacaatctc
    13741 tttactcttg ttcatgaaac aggtcacagt atgcattcaa gctatactcg tgaaactcag
    13801 ccttatgttt acggagatta ctctatcttt ttggctgaga ttgcctcaac taccaatgaa
    13861 aatatcttga cggagaaatt attggaagaa gtggaagacg acgcaacacg ctttgctatt
    13921 ctcaataact tcctagatgg tttccgtgga acaattttcc gccaaactca atttgctgag
    13981 tttgaacacg ccattcacca agcagatcaa aatggggagg tcttgacaag cgatttccta
    14041 aataaactct acgcagactt gaaccaagag tattatggtt tgagtaagga agacaatcct
    14101 gaaatccaat acgagtgggc tcgcattcca cacttctact ataactacta tgtatatcaa
    14161 tattcaactg gctttgcggc cgcctcagcc ttggctgaaa aaattgtcca tggtagtcaa
    14221 gaagaccgtg accgctatat cgactacctc aaggcaggta agtcggacta tccacttaat
    14281 gtcatgagaa aagctggtgt tgatatggag aaggaagact acctcaacga tgcctttgca
    14341 gtctttgaac gccgtttaaa tgagtttgaa gcccttgttg aaaaattagg attggcataa
    14401 aatggttgaa tcgtatagta agaatgctaa ccataacatg cgtcgtcctg tcgtcaaaga
    14461 agaaattgta gacttgatgc gtcagcgtca aaagcaggtc acaggtttct tgaaagaatt
    14521 ggaagacttt gcccgcaagg aaaatattcc tattattccc catgaaacgg ttgcttattt
    14581 ccgttttatt atggaaacca tgcagcctaa aaatattctg gaaattggga cggctatcgg
    14641 tttttcagct ctcttgatgg ctgaacatgc gccaaatgct aagattacaa ctattgatcg
    14701 taatccagaa atgattggtt ttgccaagga aaattttgcc cagtttgaca gtcgcaagca
    14761 aatcactctc ctagagggag atgcggtgga tgtcttatct acactgacag agtcttatga
    14821 tttcgtattt atggattctg ccaagtctaa atacatcgtc tttctgccag aaatcctcaa
    14881 acatttggaa gttggtggtg tggttgtctt ggatgatatt tttcaaggtg gtgatgttgc
    14941 caaggatatt atggaagtcc gtcgtggtca gcgaaccatt tatcgaggcc ttcaaaaatt
    15001 atttgatgca accttagaca atccagaact caccgcaaca ttagtgcctt taggagatgg
    15061 tattctcatg cttcgtaaaa atgtagcaga tgttcaactg tctgaaagcg aatgattttc
    15121 agaaaaattt aagaaaaaat agtaaaatag atagagtaac acttatctca aaggagtaga
    15181 catgaagaaa aaattattgg caggtgccat cacactatta tcagtagcaa ctttagcagc
    15241 ttgttcgaaa gggtcagaag gagcagacct tatcagcatg aaaggggatg tcatcacaga
    15301 acatcaattt tatgagcaag tgaaaaacaa cccttcagcc caacaagtct tgttaaatat
    15361 gaccatccaa aaagtttttg aaaaacaata tggctcagag cttgatgata aagaggttga
    15421 tgatactatt gccgaagaaa aaaaacaata tggcgaaaac taccaacgtg tcttgtcaca
    15481 agcaggtatg actcttgaaa cacgtaaagc tcaaattcgt acaagtaaat tagttgagtt
    15541 ggcagttaag aaggtagcag aagctgaatt gacagatgaa gcctataaga aagcctttga
    15601 tgagtacact ccagatgtaa cggctcaaat catccgtctt aataatgaag ataaggccaa
    15661 agaagttctc gaaaaagcca aggcagaagg tgctgatttt gctcaattag ccaaagataa
    15721 ttcaactgat gaaaaaacaa aagaaaatgg tggagaaatt acctttgatt ctgcttcaac
    15781 agaagtacct gagcaagtca aaaaagccgc tttcgcttta gatgtggatg gtgtttctga
    15841 tgtgattaca gcaactggca cacaagccta cagtagccaa tattacattg taaaactcac
    15901 taagaaaaca gaaaaatcat ctaatattga tgactacaaa gaaaaattaa aaactgttat
    15961 cttgactcaa aaacaaaatg attcaacatt tgttcaaagc attatcggaa aagaattgca
    16021 agcagccaat atcaaggtta aggaccaagc cttccaaaat atctttaccc aatatatcgg
    16081 tggtggagat tcaagctcaa gcagtagtac atcaaacgaa tagtccaaat caatgagtca
    16141 gggaaaaaac tcgacttcag gaaaaaatga agcaaacatt cccacaataa aacgcatagt
    16201 acaaggtttg tactgccccc caaaaaagtt agacaattaa tttatccgaa ggatttagtt
    16261 ctgtattgca cagagctaag tccttttagt tttatcttaa ttctcttatt gttgtaataa
    16321 tcaatatagt ctataatggc ttgttccaat tgattaagtg atttaaatgt ttgctcatag
    16381 ccataaaaca tttcggattt taaaatgcca aagaaagatt ccatcctacc gttgtcttgg
    16441 ctgtttcctt tgcgtgacat agatgcttga attcccttac tctctaggaa gcgatgataa
    16501 gaatcgtgtt ggtattgcca gccttggtca ctatggagaa tcgtattctc gtagtgcttc
    16561 tctttgaatg cctgttccaa cattaacgat caatcaattt aatcatatac ctaagattag
    16621 aattgtttat cccaaattta tttgaaagct tctctaagct atatccttgt tttctaagtt
    16681 catagatctg aactttatca tcataattca atttcataat aaaaacaccc caaaagttag
    16741 attttttctg tctaactttt ggggtgtagt tcatgtacac ctgatatgat gcgttttata
    16801 attttaaaga ctttttgacc agcctcattt tttaacttga tactcagtga aaagcaaaga
    16861 ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg cagataaaac
    16921 ttgtgaggta accaacatat ataatgtgaa gctgacgtgg tttgaataga ttttaggagg
    16981 gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt aagctagagt
    17041 tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca tcttagtata
    17101 gaaaagtgaa tctgaaatag tacataactg cttctaaaac attcttataa attgatttaa
    17161 attctcaaat catattattc agttcttatt tcattttgct ctacaatcct gttgagaaga
    17221 cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa ggttcttttg
    17281 tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag gctaggctat
    17341 aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc aaaatcatgg
    17401 gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag aagtggttct
    17461 ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc gacaattaga
    17521 atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg ctgagttgta
    17581 ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt tgaacgaaaa
    17641 gcctggattt gttgcgggta aatagcttcc agggttgcaa ttttcaaacc ttctaacttc
    17701 ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt atggagttga
    17761 ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata aatctgatca
    17821 aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga ttcaggaaga
    17881 agaggagaat caccactagc accttgaaaa cgaccttctt ggttccagag ggtacgaccg
    17941 tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca aagtctgcct
    18001 ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact tcgcctgcag
    18061 agacaatcat ttgatccaaa tctagagcaa ttttatcgat aaaaatggga taattgtgtt
    18121 tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt ttttctaagt
    18181 ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt ttcttttcag
    18241 acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct cccaaaagcg
    18301 ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct tctagggcat
    18361 tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc accaatgttt
    18421 ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac tcatccaaat
    18481 accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga caagtgaaag
    18541 tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca aaagggtact
    18601 tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt ttaaggcata
    18661 atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa tcggaaagaa
    18721 ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga gtcccaaaat
    18781 caaaagtaaa tttgatggac tgaggccagg aaccaagacg ccaagggcca atagtgcgcc
    18841 tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat ttaaggcata
    18901 gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa tcttgtctcg
    18961 gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa tagctcccgc
    19021 aaagctccat aatacaaaaa cctgataatt ttcaagcagg tattcaatcg ggtaggaaaa
    19081 taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa cattttcttt
    19141 aaagtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc ctaagattgc
    19201 tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta caatcccttt
    19261 aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat ttcaaaaaat
    19321 ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata aacaaatgct
    19381 tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag ggagagataa
    19441 cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg tattggtgaa
    19501 tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct gagccgtagg
    19561 acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc atgaagtaga
    19621 caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct cgaaagtttt
    19681 cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa tagtaactag
    19741 ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt tcttggacac
    19801 tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga agttcagtga
    19861 tatgactctt ataggccttg tctattccat tgataaatga agcatcattt tcttttgttg
    19921 tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag agggcatcgt
    19981 agttgatttc ctcaggatgc tgccagccag agaggtcaat aatcggtttg tctaagtgtt
    20041 tcaaagcctg tgctatattg gattttgttt taaacgattg gctgtcatta agtgggcgat
    20101 tgatgattaa aatgaacatc ataatcccaa aaaaactaaa taaaataagt ggatgaattt
    20161 gttttctcat atcttataag tctaccctaa aaatcaaaaa aaatcaaaaa aatcaaaaaa
    20221 atgggttaag gaagagactt tagagcattt tttcattcaa gagtgcggaa tgatttgaaa
    20281 tatggtataa taaaagggaa tttctacaga aaagagaaga ttatgtcaaa ttttgccatt
    20341 attttagcag cgggtaaagg gactcgcatg aaatctgatt tgccaaaagt tttgcacaag
    20401 gttgcgggta tttctatgtt ggaacatgtt ttccgtagtg tgggagctat ccaacctgaa
    20461 aagacagtaa cagttgtagg acacaaggca gaattggttg aggaggtctt ggctggacag
    20521 acagaatttg tgactcaatc tgaacagttg ggaactggtc atgcagttat gatgacagaa
    20581 cctatcttag aaggtttgtc aggacacacc ttggtcattg caggagatac tcctttaatc
    20641 actggtgaaa gcttgaaaaa cttgattgat ttccatatca atcataaaaa tgtggccact
    20701 atcttgactg ctgaaacgga taatcctttt ggctatggac gaattgttcg taatgacaat
    20761 gctgaggttc ttcgtattgt tgagcagaag gatgctacag attttgaaaa gcaaatcaag
    20821 gaaatcaaca ctggaacata cgtctttgac aacgagcgtt tgtttgaggc tttgaaaaat
    20881 atcaatacca ataacgctca aggcgaatac tatattacag acgtcattgg tattttccgt
    20941 gaaactggtg aaaaagttgg cgcttatact ttgaaagatt ttgatgaaag tcttggggta
    21001 aatgaccgtg tggcgcttgc gacagctgag tcagttatgc gtcgtcgcat caatcataaa
    21061 cacatggtca acggtgttag ctttgtcaat ccagaagcaa cttatatcga tattgatgtt
    21121 gagattgctc cggaagttca aatcgaagcc aatgttacct tgaaagggca aacgaaaatt
    21181 ggtgctgaga ctgttttgac aaatggtact tatgtagtgg acagcactat cggagcagga
    21241 gcggtcatta ccaattctat gattgaggaa agtagtgttg cagacggtgt gacagtcggt
    21301 ccttatgctc acattcgtcc aaattcaagt ctgggtgccc aagttcatat tggtaacttt
    21361 gttgaggtga aaggatcttc aatcggtgag aataccaagg ctggtcattt gacttatatc
    21421 ggaaactgtg aagtgggaag caacgttaat ttcggtgctg gaactattac agtcaactat
    21481 gacggcaaaa acaaatacaa gacagtcatt ggagacaatg tctttgttgg ttcaaattca
    21541 accattattg caccagtaga acttggtgac aattccctcg ttggtgctgg ttcaactatt
    21601 actaaagacg tgccagcaga tgctattgct attggtcgcg gtcgtcagat caataaagac
    21661 gaatatgcaa cacgtcttcc tcatcatcct aagaaccagt aggagcctat catggagttt
    21721 gaagaaaaaa cgcttagccg aaaagaaatc tatcaaggac caatatttaa actggtccaa
    21781 gatcaggttg aattaccaga aggcaaggga actgcccaac gggatttgat tttccacaat
    21841 ggggctgtct gtgttttagc agtaacggat gaacaaaaac ttatcttggt caagcagtac
    21901 cgcaaagcta tcgaggctgt ctcttacgaa attccagccg gaaaattgga agtaggagaa
    21961 aacacagccc ctgtggcagc tgcccttcgt gaattagagg aagaaacagc ctatacaggg
    22021 aaattagaac tcttgtacga tttttattca gctattggct tttgtaatga gaagttaaaa
    22081 ctatatttag caagcgattt aacaaaagtg gaaaatccgc gtccgcagga tgagaatgaa
    22141 accttggaag tccttgaagt gagcttagaa gaagcgaaag aattaatcca atcaggtcgt
    22201 atttgtgatg ccaagacaat tatggctgtt cagtattggg agttgcagaa aaaatagagg
    22261 aggtcagtat gggtaaatct ttattaacgg atgaaatgat tgaaagagct aatagaggcg
    22321 aaaaaatttc aggtcctcct ttgctagatg ataatgagga aactaagatt ttaccaacct
    22381 cttcttcccg ttttggttat gccaatccta aggatcatgg ttttagccag gaaaccttga
    22441 agattcaggt cgaaccatct attcataaaa gccgtcgtat tgaaaatacc aagagaaatg
    22501 tcttcaattc taagttgaat aaaatcttat ttgcggtcat ctttctcttg attttgcttg
    22561 ttttagcaat gaaacttttg taatagaaaa ggaattgaaa tgaaaatagg aattattgct
    22621 gctatgccgg aagaactggc ttatctggtc cagcatttag ataatgccca ggagcaagtt
    22681 gttttgggga atacctatca tacaggaacc attgcttctc atgaagtcgt tcttgtagaa
    22741 agtggaattg gtaaggtcat gtctgctatg agtgtggcga ttttggctga tcatttccag
    22801 gtggatgccc ttattaatac gggttcagct ggggcagtag cagaaggtat cgctgttggg
    22861 gatgtcgtga ttgctgacaa attagcctat catgacgtgg atgtcacagc ttttggctat
    22921 gcttatggac aaatggcgca acaaccgctt tatttcgaat cagacaaaac ctttgttgct
    22981 caaatccaag agagtttatc tcaattggac caaaactggc atcttggttt gattgctaca
    23041 ggagatagtt ttgttgcagg aaatgacaag atagaagcga ttaagtccca tttcccagaa
    23101 gttttagccg tggagatgga gggggcagct attgctcaag cagcgcatgc cctcaatctc
    23161 ccagtcttag tcatccgagc tatgagtgac aatgccaacc atgaagcaaa catctttttt
    23221 gatgagttta ttatcgaagc tggacgtcgc tctgcccaag tcttgttggc ctttttgaag
    23281 gctttagatt aagcggaaat ttgacagttt ttctagctta tgataagatt taagtaaaga
    23341 aaagctagaa aacgtttcag aggatattat gagtattgaa atgaccgtca gtgagattgc
    23401 agaggtctta ggattatctc gccaagcaat caataaccgt gtcaaagaat taccagaaga
    23461 agacacagat aaaaatgaca aaggggtaac agttgttacc agaagtggct tgattaagct
    23521 agaagaaatc tataaaaaaa cgatttttga agatgagcct gtcagtgaag atgtcaaaca
    23581 acgtgaactg atggagattc tagtggatga gaagaatgca gaaattcttc gtctttatga
    23641 acaattaaaa gccaaggatc gtcagttatc agaaaaagac gagcagatgc gtatcaaaga
    23701 ccgtcagatt gctgagaaag acaaacaatt agatcagcaa caacaattga cccttcaagc
    23761 catgaaggat caagaaaatc ttaagctaga gctggaccaa gcaaaagaag aagtccaatc
    23821 cactaaaaaa ggcttttttg ctcgtttatt tggaggataa tcaaggagct gtttaggtta
    23881 aatgctaacc tgatggcttc ttttgtttgt gaatagtata gttgattaga acagagacag
    23941 tagaggagag gtacagaatg gaacgattag aagattacat tgcttttgat ttagaattta
    24001 atcagcacga aggacaaaca cacttgattc aagcatcggc agtgcgtttt agagatggtc
    24061 gggaaatcga tgcctatgat tcctatgttc ataccagcgt ccctctaaaa agctttatca
    24121 atggtttgac cgggattaca gctgagacct taaaagatgc tcctccagtt gagaaagtct
    24181 tagaagaatt ccaagagttt gtgggttctt tgctgatgat aggctacaat gctgctaaaa
    24241 gtgatttacc tattttagca gagcatggtt tagactatag ccaacagtac aaggtggatt
    24301 tgtatgatga agcttttgaa cgtcggagtt cagatttaca tggtattgcc aatctcaaat
    24361 tgcaaactgt tgcctcattt cttggatttc aaggtcagtc tcataatagt ttagaggatg
    24421 ctcggatgac ggcgcgtgtt tacgaatcct tcttagagtc ggatcaagct agggaattgt
    24481 tagagacaga aagtagctta tcaaacaatc cttttggtgg cttggacttg tctcaattat
    24541 ttgactagga gtgcctatga aacctgaaaa acctaaaaaa ttgggtctta aacagattta
    24601 cctcaatctt gataaaatcc tctttctatt tttcttgatt tttatgatag tggagtattt
    24661 gtgggtacca ttcaattcat ggttggctag cttcttatta gatcagacag gttatctttt
    24721 tatttcctat aacaatgtct tagccatcct tactcattct ccattgatta gtctagcttt
    24781 tttagccttg attgtaatta accttctggt tgcttatttt caaataggac tcctctttat
    24841 tggtgctcgt catctcctct ataatgaaaa gcgaaggcta attgagtata tccgcaaggt
    24901 tttccatgaa agttttggat ttatgaaaaa gctaacttgt gctaaagcct tgtttatctt
    24961 tttctatata gctatgcttt ttccttttat acggaaaatg ctgaagattt attatcttaa
    25021 taaaatcgtc attccagagt ttatccaagc ttatttagaa gataaatatt ggatgtggtg
    25081 gctgagcatc ctacttctat ctcttatctt tctctatgtc tctgtcagat tgatgtttgc
    25141 ccttccgaag attgtatatg atcagctgac tgttcgagaa gcagtgatgt ttagcttgga
    25201 gaaaaccaag aagagagtta ctttttatgc ttggaattta ttttacatct tgctcaaagc
    25261 acatttatta ttttatcttc ctttgattcc tttattattg gctcaaactt tggtagatga
    25321 tatcactcag agagagtctc tgattcttgg tattttgaat tttgtcgtga ttaaaaatct
    25381 ctattatatg gctctgactt attttttggt taaatttgtt tcatttttga caggaaagga
    25441 gctggatatg cttcctagga gagaaaaaga tcacatcgtg cgatggggtg tcatgacttg
    25501 tgccagtctt ttctttgcct tagaaggtta tatttatctg gaggctccca tggttcatct
    25561 acctcaactt atttctcacc gaggggtttc caatgcaaat gggattcaaa atacagtaga
    25621 gtccttggaa actacagcac aactcaaacc agacttggtg gagacggacg tgcaggaaac
    25681 aaaagatggg cagtttgtca tgatgcatga tgctaacttg aaaaatctag caggtatcaa
    25741 taaaagtcct caagacttaa acttggagga gcttaaaggg attgatattt ttgaaaatgg
    25801 ctaccagact aaaatttcaa gctttgaaga ttatctcagt cgagccaacg aacttggtca
    25861 aaaattacta attgaaatta aaaccagtaa aaaagatagt ccagacatga tgaaccgctt
    25921 tttagcccgt tatgctgcaa agctcaagat ttatggacat caaatccagt ctttagacta
    25981 ccatgttgtc gaaaaagtaa gacagtatga tgccgaactg ccagtttatt tcatcatgcc
    26041 ctacaattct gtatttccta aaacaagagc gacaggatat actatggagt actcaacctt
    26101 ggatgaatat tttgtaagca aactatggac aacggatcag aaactttatg tctggactgt
    26161 caatgattca gaagctatca gcaaatctct tcacttagga gtagatggag tgattacaga
    26221 tgatttggaa aaagttcagc gggaaataga agtagcccaa gaagatccag aatatacgga
    26281 tttgctcttg aaaaaagcat tggaattctt tgaattttag taataaaaaa gaggaactgt
    26341 tgttcctccc atgataggta agtattcttg tgaatgcttg cttttttgtg gttgcaatcc
    26401 gtttacgaga attgtttgta ttgttcttgt ttcaatttac tttatagtgc tttgaagttg
    26461 gaatgctaca ctataacttc taaaatatag taaaatgaac caaaaatagt acacaatgtg
    26521 gtataatctt cttatggcat attcaataga ttttcgtaaa aaagttctct cttattgtga
    26581 gcgaacaggt agtataacag aagcgtcaca cgttttccaa atctcacgta ataccattta
    26641 tggctggtta aagctaaaag agaaaacagg agagctaaac caccaagtaa aaggaacaaa
    26701 accaagaaaa gttgatagag atagacttaa aaactatctt actgataatc cagacgctta
    26761 tttgactgaa atagcttctg aatttggctg tcatccaact accatccact atgcgctcaa
    26821 agctatgggc tacactcgaa aaaaagaacc acacctacta tgaacaagac ccagaaaaag
    26881 tagccttatt tcttaagaat tttaatagtt taaagcacct agcacctgtt tagattgatg
    26941 aaacaggatt cgatacttat ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa
    27001 gaagaggcaa agtatctgga agaagatatc agaggatttc tttggttgca ggtctaacaa
    27061 atggtgagtt aatcgctcca atgacttacg aagagacgat gacgagcgac ttttttgaag
    27121 cttggtttca gaagtttctc ttaccaacat taaccacacc atcggttatt agagtaaaat
    27181 gaaataagaa caggacaaat cgatcaggac agtaaaatcg aattctaaca atgttttaga
    27241 agtctatatg tactattcta gtttcaatat accataactg ctcctagtca acctgcaagt
    27301 cctgtcccag ctccaagctc agctccgact caagatccta gagtggtagc aagcgcttcg
    27361 gctagctcaa cgagcacaca agctcaagag caagttgaca agtctgaact tcgtgccttg
    27421 agtcaagagt tagaccaacg cttgaaagct ttggcaacag tatctgatcc aaaaatcgat
    27481 gcaaccaagg ctgtcctcct agatgctcaa aaagctccgg aagatagtgc cttgacagag
    27541 taaggtctgc atactgcagt agagtctgtg aaggctgcct tggactctct caaagatgtg
    27601 aaagcaaatg ctagcgacag caagcctgca caggacaaga aggatgcaaa acaaggaatg
    27661 gaagatagta aggattcaga taagatgact gaaacaaact cagttccggc aggagtgatt
    27721 gtggtcagtc tacttgccct cctaggcgtg attgccttct ggctgattcg ccgtaagaaa
    27781 gagtcagaaa tccagcaatt aagcacggaa ttgatcaagg ttctaggaca gctagatgca
    27841 gaaaaagcgg ataaaaaagt ccttgccaaa gcccaaaacc ttctccaaga aacccttgat
    27901 ttcgtgaaag aagaaaatgg ctcagcagag acagaaacta aactagtaga ggagcttaaa
    27961 gcaatccttg acaaactcaa gtaaaacatg atttatgaaa tgtcagacct aaaagacatt
    28021 ttcgttcaca aaagcagtga cgagtaatcc ttgtcgttgc tttttggcta ttttggggga
    28081 taagatccgc cttgactagc aaaagaaaag attggtccaa tagtgcccga tacgattttg
    28141 cgtagcagaa agcttacaaa taaaattgaa tatagtaaaa taggattaga attattaaga
    28201 aagttggttc tttattggaa acgatagtat ttttaatctc tgtttttcta gcaggtgttt
    28261 tatccttttt ttctccttgt atttttcctc ttctgccagt ctatgctggg attttattgg
    28321 atgatcaaga aagtgcaaaa agcttttctt tgtttgggag aaaggttctc tggtcaggct
    28381 tgattcgaac actttgcttt atcgctggta tctctctcat tttctttatt ctaggctttg
    28441 gtgctggtta ctttggtcat attctctatg caaattggtt tcgatatgtc atgggagcta
    28501 ttattatcat tttgggtctt caccagatgg aaatttttca tttgaagaaa ttagaagttc
    28561 aaaaaagttt tacctttaaa aaatcagatt ctaatcgtta ttggtcagct tttttacttg
    28621 gtattacctt tagctttggt tggacacctt gtattggtcc agttttaagt tctgttttag
    28681 cacttgcggc ttctggaggc aatggtgctt ggcaaggagc gatttatact ctcatttaca
    28741 ctctgggcat ggcccttcct ttcttggtct tggcactagc ttcaggtcta gtcatgccat
    28801 attttagtaa aatcaagcgt catatgatgc tactaaagaa aattggtggt ttcctcattg
    28861 ttttaatggg aattttgtta ctattaggac aagtaaatgt tctagctgga atttttgaat
    28921 aaaggaggac aaatgaaaaa agtaatgttt gctggcttaa gtctcttgtc attagttgta
    28981 ttgatggcct gtggtcagga agaaactaaa aagactcaag cagcacaaca gccaaaacaa
    29041 caaacgactg tacaacaaat tgctgttgga aaagatgctc cagactttac attgcaatcc
    29101 atggatggca aagaagttaa gttatctgat tttaagggta aaaaggttta cttgaagttt
    29161 tgggcttcat ggtgtggtcc atgcaagaaa agtatgccag agttgatgga actagcggcg
    29221 aaaccagatc gtgatttcga aattcttact gtcattgcac caggaattca aggtgaaaaa
    29281 actgttgagc aattcccaca atggttccag gaacaaggat ataaggatat cccagttctt
    29341 tatgatacca aagcaaccac cttccaagct tatcaaattc gaagcattcc tacagaatat
    29401 ttaattgata gccaaggaaa gattggaaag attcaatttg gtgctatcag taatgcggat
    29461 gcagaagcag catttaaaga aatgaactag aatcgataaa atctgattac aagatgtagt
    29521 cagattttgg taacttctaa aactaacttc cagtttccca caacttagct tttagtatga
    29581 gaaaaacgcg tgacatcagt ggaaatccgt cttagactaa ctttcactgg ttttcttttt
    29641 cttgatatat aagggttcaa aagcgaaaag actcagaaaa agtgcacgac aaatagccct
    29701 aaaacagagt cgtcttagag taacttccag ttttgggaga gagatggaag ttactttgag
    29761 aagttacggt agtcagattt ttttagaaaa acattttata aatattcaca tatctcctat
    29821 atttatggta aaatagaatt atcagtttat tttggagtca aagatgaata tatttagaac
    29881 aaagaatgtt agtttagata aaacagagat gcataggcat ttgaagttat gggatttgat
    29941 tttgctgggt atcggagcca tggtagggac aggcgtcttt acaatcacag gtactgcagc
    30001 tgcaacactt gctggcccag ccctagtgat ttcaatcgtt atttctgcct tgtgtgtggg
    30061 attatcagcc ctcttttttg cagaatttgc ctcgcgagta cccgctacag gaggtgccta
    30121 tagttacctc tatgctatct taggagaatt ccctgcctgg ttggctggtt ggttaaccat
    30181 gatggagttc atgacagcca tatcaggcgt agcttcgggt tgggcagctt attttaaagg
    30241 cttgctctct caatacggga tagcccttcc tcaggcttta aatggtacct ttaatcctca
    30301 agcagggaca tttgttgatt tattgcctat tcttgtcttg gtcttggtga cttcgcttgt
    30361 tttactaaat gccaaggcag ccttacgctt taattcgatt ctagttattt tgaaattttc
    30421 cgctttagct ctctttgttt tagtaggaat ttggaatatt aagtttgata attggagcaa
    30481 ttttgctcct tacggttttg gacaaatcta tggagctagc actggtatta tggctggtgc
    30541 gtccttgatg ttcttcggtt ttttgggatt tgaatccatc tctatggctg tagatgaagt
    30601 caagactcct caaaaaaata ttcctagagg gattgtctta tcgctttcta tcgtaaccat
    30661 tctctatgcc ttggtgaccc ttgttttgac tggtgtggtt cactatagtc atttaaatgt
    30721 cgatgatgcc gttgcctttg cccttcgtag tgttgggatt agttgggcag ccaactatgt
    30781 gtcattagtg gctatcttga ccttgattac agtttgtatt tcgatgacct atgccctatc
    30841 gcgtatgatt tacagtttag cacgtgacgg cttagtgcct gctgccttta aggaactgac
    30901 gaagactagc aagataccaa agaatgctac tatcttgaca ggtctagctt cagcagtagc
    30961 agcaggaatg ttcccactag ccagtattgc agccttttta aatatttgta ccttagccta
    31021 cttgatcatg ttggcttatg gtctgattcg cttacggaaa gaaaaaggaa tgcccaaagc
    31081 tggggaattt aaaacaccat tggtacctct gttaccaatt ttatcgatca tcatttgttt
    31141 atccttcatg ttacagtata atatgaatac ctggattgct ttcctagttg cgttgttagt
    31201 aggaagtatt atttacttca cttatggcta taagcattct accatagaag aataaagtga
    31261 aagtctattg agttgttgac actcagcaga tttttatatg tgaaagaaat ttcaaatttt
    31321 ttctaaaaat atcttgacag attaaatttt caggagtaga atatttacta gttaattaaa
    31381 tggttaagga gttgttcatg aagaaacaaa atttattttt agtcctgtta agtgtctttc
    31441 ttttgtgctt gggggcttgt ggtcaaaagg aaagtcagac aggaaagggg atgaaaattg
    31501 tgaccagttt ttatcctatc tacgctatgg ttaaggaagt atctggtgac ttgaatgatg
    31561 ttcggatgat tcagtcaagt agtggtattc actcctttga accttcggca aatgatatcg
    31621 cagccatcta tgatgcagat gtctttgttt accattctca tacactcgaa tcttgggcag
    31681 gaagtctgga tccaaatcta aaaaaatcca aagtgaaggt cttagaggct tctgagggaa
    31741 tgaccttgga acgtgtccct ggactagagg atgtggaagc aggggatgga gttgatgaaa
    31801 aaacgctcta tgaccctcac acatggctag atcctgaaaa agctggagaa gaagcccaaa
    31861 ttatcgctga taaactttca gaggtggata gtgagcataa agagacttat caaaaaaatg
    31921 cgcaagcctt tatcaaaaaa gctcaggaat tgactaagaa attccaacca aaatttgaaa
    31981 aagcgactca gaaaacattt gtaacacaac atacagcctt ttcttatcta gcgaagagat
    32041 ttgggcttaa tcaacttggt attgcaggta tctctcctga acaagaacca agtccacgac
    32101 aactaacaga aattcaggaa tttgttaaga cctataaggt taaaacgatt tttacagaaa
    32161 gtaacgcttc ttcaaaagta gctgaaactc ttgtcaaatc aacaggtgtg ggtcttaaaa
    32221 ctctgaatcc tttagagtca gacccacaaa atgacaagac ctatttagaa aatcttgaag
    32281 aaaatatgag tattctagca gaagaattaa agtgaggaaa gaatgaaaat caataaaaaa
    32341 tatctagcag gttcagtggc agtccttgcc ctaagtgttt gttcctatga acttggtcgt
    32401 caccaagctg gtcaggttaa gaaagagtct aatcgagttt cttatataga tggtgatcag
    32461 gctggtcaaa aggcagaaaa tttgacacca gatgaagtca gtaagagaga ggggatcaac
    32521 gccgaacaaa ttgttatcaa gattacggat caaggttatg tgacctctca tggagaccat
    32581 tatcattact ataatggcaa ggttccttat gatgccatca tcagtgaaga acttctcatg
    32641 aaagatccga attatcagtt gaaggattca gacattgtca atgaaatcaa gggtggctat
    32701 gtgattaagg tagacggaaa atactatgtt taccttaaag atgcggccca tgcggacaat
    32761 attcggacaa aagaagagat taaacgtcag aagcaggaac gcagtcataa tcataactca
    32821 agagcagata atgctgttgc tgcagccaga gcccaaggac gctatacaac ggatgatggt
    32881 tatatcttca atgcatctga tatcatcgaa gatacgggcg atgcctatat cgttcctcat
    32941 ggcaatcact tccactatat tcctaagagt gatttatctg ccagtgaatt agctgctgcc
    33001 caagcctatt ggaatgggaa gcagggatct cgtccttctt caagttctag tcataatgca
    33061 aatccagctc aaccaagatt gtcagagaac cacaatctga ctgtcactcc aacttatcat
    33121 caaaatcaag gggaaaacat ttcaagcctt ttacgtgaat tgtatgctaa acccttatca
//
LOCUS       DAVLIK010000021        31144 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLIK010000021 DAVLIK010000000
VERSION     DAVLIK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31144
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.021"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..1203
                     /locus_tag="VXE87_001101"
     CDS             <1..1203
                     /locus_tag="VXE87_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV0842656.1"
                     /translation="STLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTI
                     ISWNSLRFQPYFTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHS
                     SRSPFNSKEPWFFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYP
                     ENDESYNVPNQYFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSDKKYTGGV
                     KLSVYRDISTTPVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNG
                     QRYKTRLSIDWEMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEW
                     KDNKRTSLNDEVFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLL
                     EMIFTSQN"
     gene            complement(1425..1901)
                     /locus_tag="VXE87_001102"
     CDS             complement(1425..1901)
                     /locus_tag="VXE87_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0842657.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            2124..5327
                     /locus_tag="VXE87_001103"
     CDS             2124..5327
                     /locus_tag="VXE87_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV0842658.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENSDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNREKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            5707..6083
                     /gene="tnpA"
                     /locus_tag="VXE87_001104"
                     /pseudo
     CDS             5707..6083
                     /gene="tnpA"
                     /locus_tag="VXE87_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(6471..7100)
                     /locus_tag="VXE87_001105"
     CDS             complement(6471..7100)
                     /locus_tag="VXE87_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0842659.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(7110..8111)
                     /locus_tag="VXE87_001106"
     CDS             complement(7110..8111)
                     /locus_tag="VXE87_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0842660.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(8142..8783)
                     /locus_tag="VXE87_001107"
     CDS             complement(8142..8783)
                     /locus_tag="VXE87_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0842661.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(8802..9617)
                     /locus_tag="VXE87_001108"
     CDS             complement(8802..9617)
                     /locus_tag="VXE87_001108"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0842662.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            9888..10322
                     /locus_tag="VXE87_001109"
     CDS             9888..10322
                     /locus_tag="VXE87_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0842663.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            10334..11524
                     /locus_tag="VXE87_001110"
     CDS             10334..11524
                     /locus_tag="VXE87_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0842664.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            11535..12026
                     /locus_tag="VXE87_001111"
     CDS             11535..12026
                     /locus_tag="VXE87_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0842665.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLDEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            12041..12820
                     /locus_tag="VXE87_001112"
     CDS             12041..12820
                     /locus_tag="VXE87_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0842666.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            12807..13625
                     /locus_tag="VXE87_001113"
     CDS             12807..13625
                     /locus_tag="VXE87_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0842667.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            13625..13945
                     /locus_tag="VXE87_001114"
     CDS             13625..13945
                     /locus_tag="VXE87_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0842668.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLSIQDDLVSLQIAKGVVIHVEKESVMGKTKE
                     LLFK"
     gene            14007..15875
                     /locus_tag="VXE87_001115"
     CDS             14007..15875
                     /locus_tag="VXE87_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0842669.1"
                     /translation="MDGNQCRDYILSHCSKDYEKVKSSLERLMDNRFMFDSPWDMEPC
                     SKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYMVEGDKDYIQKCKFFLFDWI
                     EQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKILVSLEKQIDFMK
                     SHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQIETQILGDGSQ
                     FEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLDGRTLAFGDSDS
                     TETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFEKRAWQPKSMIF
                     EDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQSQPIFIDAGRYSYREIYER
                     YLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHYIEGAYWSAEPD
                     LPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGKINQLRLWSEVD
                     FDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRHSVYQTDDREVE
                     NALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKINERMIRLQC"
     gene            15935..16936
                     /locus_tag="VXE87_001116"
     CDS             15935..16936
                     /locus_tag="VXE87_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0842670.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(17046..17381)
                     /locus_tag="VXE87_001117"
     CDS             complement(17046..17381)
                     /locus_tag="VXE87_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842671.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(17392..17634)
                     /locus_tag="VXE87_001118"
     CDS             complement(17392..17634)
                     /locus_tag="VXE87_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842672.1"
                     /translation="MKKEKRQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(17645..18187)
                     /locus_tag="VXE87_001119"
     CDS             complement(17645..18187)
                     /locus_tag="VXE87_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV0842673.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIRNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(18203..18397)
                     /locus_tag="VXE87_001120"
     CDS             complement(18203..18397)
                     /locus_tag="VXE87_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842674.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            18563..19513
                     /gene="rsmH"
                     /locus_tag="VXE87_001121"
     CDS             18563..19513
                     /gene="rsmH"
                     /locus_tag="VXE87_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0842675.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            19525..19842
                     /gene="ftsL"
                     /locus_tag="VXE87_001122"
     CDS             19525..19842
                     /gene="ftsL"
                     /locus_tag="VXE87_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0842676.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            19846..22098
                     /locus_tag="VXE87_001123"
     CDS             19846..22098
                     /locus_tag="VXE87_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEV0842677.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSPLQSFMETQ
                     MDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEGITEDFVWRDILYQSNYE
                     PGSAMKVMTLASSIDNNTFPSGEYFNSSEFKIADATTRDWDVNDGLTTGGMMTFLQGF
                     AHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSF
                     GQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKEAA
                     STTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGST
                     NYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPA
                     KNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAP
                     NQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGSVVQKQDVRTNTAIKN
                     IKKIKLTLGD"
     gene            22100..23080
                     /locus_tag="VXE87_001124"
     CDS             22100..23080
                     /locus_tag="VXE87_001124"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0842678.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIAAVVVSFLVALFSKQLTNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            23689..25794
                     /locus_tag="VXE87_001125"
     CDS             23689..25794
                     /locus_tag="VXE87_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0842679.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGPTGVGKTELAKQLALDMFGTKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLV
                     EVNKTLSKKDIDLAVSEAAKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLD
                     AKHLEADMEDGVLVIREKA"
     gene            26244..26579
                     /locus_tag="VXE87_001126"
                     /pseudo
     CDS             26244..26579
                     /locus_tag="VXE87_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(26646..27128)
                     /locus_tag="VXE87_001127"
     CDS             complement(26646..27128)
                     /locus_tag="VXE87_001127"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0842680.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWARLILEQGISDDAFERHVI
                     "
     gene            complement(27223..28707)
                     /locus_tag="VXE87_001128"
     CDS             complement(27223..28707)
                     /locus_tag="VXE87_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0842681.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            28860..30467
                     /locus_tag="VXE87_001129"
     CDS             28860..30467
                     /locus_tag="VXE87_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0842682.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            30670..30798
                     /locus_tag="VXE87_001130"
     CDS             30670..30798
                     /locus_tag="VXE87_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV0842683.1"
                     /translation="MCFALAACGQSGSDTKTYSSTFSGNPTTFNYLLDYYADNTVN"
     gene            complement(30791..31144)
                     /locus_tag="VXE87_001131"
                     /pseudo
     CDS             complement(30791..31144)
                     /locus_tag="VXE87_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9542 a         5604 c         6935 g         9063 t
ORIGIN      
        1 agtacacttt ggcttttaaa ccattatcac tatcaagata gttgtaaaaa tgcagaaggt
       61 ggtttgattt tatcaagata tgcaggtcct ggtagccacc gctaccctgt tggtttttca
      121 ggggacacta ttattagttg gaattcctta agatttcaac cttattttac agcgacagca
      181 tctaatatcg gttatagttg gtggagccat gatatcggtg ggcacatgct gggggattat
      241 gacgaagagc tacaaactag atggctacag tttggtgttt ttagtccgat tactcgatta
      301 catagttcta gaagtccttt taatagtaaa gaaccttggt ttttttcaga aacaacatct
      361 aagattatga agaaatacct tcgtttgaga catcagatga ttccctatct atataccatg
      421 aatgtaaaga cacatgagga aggtgcccca ttaatcagtc caatctatta tttctatcca
      481 gagaatgatg agagctataa tgttccaaac caatactttt ttggaacaga actgatggtg
      541 gctcccattg tagaaaagat ggatttgaca ttccaatctg caaaagtaga tgtatggttc
      601 cctgaaggtg aatggtatga ctttttttca gataaaaaat acacaggtgg tgtgaagtta
      661 agtgtttata gggacatctc gactacgcct gtgtttgcaa aaagtggtgc aatcattccc
      721 ttggttggtt ctgagatagg tatgggtgtt gatttacctg aagttgtaga ttggtatgta
      781 ttcccaggaa aacaacattc ttttgaaatg cttgaagatc aaaatggtca aagatataaa
      841 acaagattat caatcgattg ggaaatggga atggtagagt tagcattaca aggagattct
      901 agtatcgttc caagcaatag aaaacataga attcatttta aaggaacgaa tgtgtctata
      961 attgaattgc caaataagaa tgatacagct aaatttgaat ggaaagataa taaaaggaca
     1021 tctttaaatg acgaagtttt tagactacta aagacagctt ctcttccata tgaattaaaa
     1081 gatagattgt taaatcaatt catcaatgcg aaaaactctc atgacttaat gaatatcttg
     1141 catcatcagg ataaggaatt gagagggcgt ttgttggaaa tgatatttac tagccaaaac
     1201 taattgatat aattagaaag tcatttgttt agtgtatatg aagattctgt atggtattcg
     1261 ttatcactgg tcacattgaa aatgtgaaat aagcacctac aacatagact ttacaacact
     1321 tcatgtttca tatcatgggg tgtttttcta tttaagtcaa agccaatcaa aaaatctcac
     1381 tattcatcag gttaaaggaa acctaatcat agtgagattg tgaattatag tagagtttgt
     1441 atcgcctctt caatttgttt tgggtctgtt tttgaagaaa agcgttcaaa gacttgccca
     1501 tctcgaccga tgagaaactt agcgaaattc cattcgactc gttttcctag tgggccggat
     1561 ttctggtctt ttaaccagac atagagaggg tctgcttcct taccgttgac cttaatcttg
     1621 gcaaaacgtg ggaaggtggt ttgaaaatgt aggctacaga aggcgttgat ttcctctgcg
     1681 ctgccgggtg cttgtcccat aaactgattg caagggaaat ccaatatttc gaagccctga
     1741 tcttgatagc gttcatagag ttcttgaagt ccctggtact ggggcgttaa accacatcca
     1801 gtagcagtgt tgacaatcaa gagaactttg ccacgatagc tatccaaggg agttgcttgg
     1861 ttgttttggt tcaaaacgga aaaatcataa agtgaagtca tgagggcctc ttttcttttt
     1921 ctacattgta acagttttta cttttttcgt cgagtcggat ggaagatatt gttgaagaat
     1981 aagccctcaa tatgatagaa accgtttaca aataacttta aaaatggtat gatttaatta
     2041 aaccggttta ctttgttgct ataaatctct aatttgagat ttagttccta ttgattttac
     2101 aatatgttta ttggagtgta tacatgcaaa caaaaacaaa gaagctcatt gtgagtttgt
     2161 cttcacttgt tttatcagga tttttattaa accattatat gacagttgga gcggaagaaa
     2221 cgactacgaa taccattcag caaagccaga aggaagttca gtatcagcaa agggatacaa
     2281 aaaatttagt tgaaaatggt gattttggtc agacggagga cggaagcagt ccgtggacag
     2341 gaagcaaagc tcaggggtgg tcagcttggg tagaccagaa gaatagttct gcagatgcct
     2401 caactcgagt cattgaggct aaggatgggg ctatcactat ctcaagccct gagaaattaa
     2461 gggcagcggt tcaccgtatg gttcctattg aagctaagaa aaagtataaa ctgcgtttca
     2521 agattaaaac agataataaa gtcgggattg ccaaggttcg tatcattgag gaaagtggta
     2581 aggacaagcg attgtggaat tctgcaacga cgtcaggaac aaaggactgg cagaccattg
     2641 aagcagacta tagcccgact ttagatgttg ataaaatcaa gctggagtta ttctatgaaa
     2701 caggaactgg gactgtttcc tttaaggata ttgagctggt agaggtagca gcccagcttt
     2761 ctgaggattc tcaaacagat aaacagcttg aggaaaagat tgatttacca attggaaaaa
     2821 aacatgtttt ttctcttgcg gactatactt ataaggtaga aaattctgac gttgcttcag
     2881 tcaaaaatgg aattttagaa cctcttaagg aagggacaac caatgtcatt gtcagtaaag
     2941 atggcaagga agtgaaaaag attcctttga agattctagc ctctgttaag gatgcataca
     3001 cagcccgttt ggatgactgg aatggcatca tcgctgggaa tcaatactat gattctaaaa
     3061 atgaacagat ggccaaatta aaccaggaat tggaaggaaa ggtagctgat agcctatcta
     3121 gtatttcaag tcaggcggac cgcacctatt tgtgggaaaa attttcaaat tataaaatgt
     3181 ctgcaaatct gactgccact tatcggaaat tggaggagat ggccaagcaa gtgaccaatc
     3241 cttcttctcg ttattatcaa gatgaaactg tcgttcgaac agtcagggat tccatggaat
     3301 ggatgcataa acatgtctac aatcgtgaaa agagcattgt tgggaactgg tgggattatg
     3361 aaatcggtac acctcgtgcc atcaacaata ccttgtctct gatgaaagaa tacttctctg
     3421 atgaggaaat taaaaaatat acagatgtga ttgaaaaatt tgtaccagat cccgaacatt
     3481 tccgaaagac gactgataac ccatttaagg ctctaggtgg aaacttagtt gatatgggaa
     3541 gagtaaaagt aatagctggt ttactgcgta aggatgatca agaaatttct tctaccattc
     3601 gctcgattga gcaagtgttc aagttggtag accaaggtga aggtttttat caagatggat
     3661 cctatatcga ccacaccaat gttgcctata cgggtgctta tgggaatgtt ttgattgatg
     3721 gcctgtctca actgttgcca gtcattcaaa agaccaagaa tccaatcgat aaagataaaa
     3781 tgcaaaccat gtaccactgg attgataaat cgtttgctcc tttgctggtg aatggagagc
     3841 tgatggatat gagtcgtgga cgctcgatca gtcgtgcaaa tagcgagggg cacgtggccg
     3901 cagtagaagt actaagaggg attcaccgaa tagcggatat gtctgaagga gaaaccaaac
     3961 aacgtttgca gagtcttgtg aagaccattg ttcaatcgga tagttattat gatgtcttta
     4021 agaatttgaa gacttataag gatatcagtt tgatgcaatc cttgttaagt gatgcaggag
     4081 tcgcaagtgt tccaagaaca agttacctat ctgcctttaa caagatggat aaaacagcca
     4141 tgtacaatgc agagaaaggg tttggatttg gcttgtcact cttttccagt cgtaccttga
     4201 attacgaaca catgaacaag gaaaataaac gtggttggta tacgagtgat gggatgttct
     4261 atctttacaa tggcgatttg agtcactata gcgatggcta ctggccaaca gttaatccat
     4321 ataagatgcc tggtacaaca gagacggatg ctaagagagc ggatagcgat acaggtaaag
     4381 ttttaccgtc tgctttcgtt ggaacgagca aactagatga tgccaatgcg acagcaacca
     4441 tggatttcac caactggaat caaacattga ctgctcataa gagctggttt atgctaaagg
     4501 ataagattgc ctttttagga agcaatatcc aaaacacttc aacagatact gctgcaacta
     4561 caatcgacca gagaaaactg gaatcaagta atccatataa agtctatgtc aatgataaag
     4621 aagcctccct tacagaacaa gaaaaggatt atcctgaaac ccaaagtgtc tttttagaat
     4681 cgtccgattc gaaaaagaat attggttact ttttctttaa gaagagttca atcagcatga
     4741 gtaaggcttt gcaaaaggga gcctggaagg atatcaatga aggacagtca gacaaggaag
     4801 ttgaaaatga atttcttacg attagtcagg ctcataagca aaatggagat tcttatggct
     4861 atatgctcat tcctaacgtg gatcgtgcca ccttcaatca aatgataaaa gagttagaaa
     4921 gtagcctcat cgaaaataac gaaacccttc agtctgttta tgatgccaaa caaggagttt
     4981 ggggcattgt gaaatatgat gattctgtct ctactatttc caaccaattc caagttttga
     5041 aacgtggagt ctataccatt cgaaaagaag gggatgaata taagattgcc tactataatc
     5101 ctgaaaccca ggaatcagct ccagatcagg aagtctttaa aaagctagag caagcagctc
     5161 agccacaagt acagaattca aaagaaaagg aaaaatctga agaggaaaag aaccattcgg
     5221 atcaaaagaa tctccctcag acaggagaag gtcagtcaat cttggcaagt ctagggttct
     5281 tgctacttgg ggcgttttat ctattccgta gaggaaagaa caactaattt gttcatcatc
     5341 tagatgaatt acatgaaact gtggaaaata gaaaaaatcc gaagaaggcc aaatatcttc
     5401 ggatttttct tttaaaaaag gataagttga tacttatcct ttttacttca ttatgtgact
     5461 atagcgtttt gaaactagaa taggacatca taactgctaa aagatttcta taaattcatt
     5521 tgattttcct aatcaatttg ttcgtatcct atttcactcc actatattag tccgtctcgc
     5581 tccgtgaggt gcgagacaaa acaaccaccc gctatacggg tgcgcgtcga aggttatacc
     5641 aaaaaaactc caaacgcgat acaataaagg tgttcaatcc acttgtaaag cgaaaggaga
     5701 aaaaatatgg cacaaaaggc tcatagttta tctcacacaa agtggaggtg ttctatcaca
     5761 ttgtgttcac ccctaagtat agacgaaaag tcatctataa tcaatataga agtagtttag
     5821 gcgaaatatt tcatcgcttg tgtagttata aaggtgttga aatgatcgag ggtcacttaa
     5881 tgccagacca tgtacacatg ttagtcagta ttccgtcgag gctaagtgtt tcaagtttta
     5941 tggggtattt aaaaggcaaa agtgcactca tgatgtttga caaacacgcc aatctcaagt
     6001 acaagtttgg gaatcggcat ttctgggcgg aaggttatta tgtaagtcca gtagggctta
     6061 ataaagccac aattaagaaa tatagtcaag attaaagaaa ttatccagtg gatgatttct
     6121 tcacgagtat gaaaatttga gaacgagtaa agcatgatat atagtaaaat gaaataagaa
     6181 cagaacaaat cgatcaggac agtcaaatcg atttttaaca atgttttaga agtagatgtg
     6241 tactattcca gtttcaatct actatagcac tagataaatt gagtgtaaaa gaatatgagg
     6301 atccctttag ggatagtggt aagtaatacc aaagtctctt aaagaggcaa gtgacgagtc
     6361 aagagcaata aggcttgaac aacgtgaaag ccagcgtctt taggcgcttg gctgatgatt
     6421 tgggcttata gctctgggat aaaccacccg tttgacgggt ggttatgatt ttatctgagt
     6481 gtaacatact gttgggcaat ctcgctgatg cggtcaaagt tgccttggga agcgagttta
     6541 ttgagttcgc caccaattcc aacggcatct gcaccagcag cgaaccattg agggatgttg
     6601 tttaggccga ctcctccggt taccattacg gaaacttgtg ggatcggtgc cttgactgca
     6661 gagatatatg ctggactgag agtactacct gggaagagtt tgatgatttc actaccggct
     6721 tcaagtgcag tcgtgatctc tgtgagggta atacagcctg gaatgtacgg tgtgctgtag
     6781 agattgcaca ttttcgcagt ttcagcatgg aaagatggag aaacaacgta atttgctcca
     6841 gctagaatgg catctctagc agttacggca tcaagcacag tacctgcacc gatacaaaca
     6901 ctctgatcgt cctgatacaa gtctacaagt tccttgatga tttgtcctgc atactgattg
     6961 gtataggcga tttcaatagc tttgataccg cccttgatac aagcaatcga ggcttgtagt
     7021 ccttcttcct ttgtatttcc tcgaatgaca gcgacaattt tctgtttttt tagttcaata
     7081 atcgtatctg atttggtcat gtaattctcc taacgaatga tatcttgtgc atttgccagt
     7141 aaattttcaa tactagttgc ggaagtggag agatggtctc ctggaagagt gcatttgaga
     7201 gttgcgctcg caactgcaaa gtcaatggta gtttttaggg aggaatgatg gagtagttgg
     7261 taaagggcac cagatataaa ggcatccccg ctaccaattc gttgatagac tgcagttttt
     7321 agttggacag actcttcaaa tcgttcttcc agagcatagg cttgatagac atttttgtct
     7381 tgctcatcac tagatcggag ggtatggaaa atggccttga aaccataggc ttcttttaaa
     7441 agtcgcatgc gattttccac ctcttctagg ctagcactgt ctcttggaaa catctctaga
     7501 ttttggtcat caatcatgag aggatcaata ccgaagcaat agtcagtaaa acgtgcaaac
     7561 ttagaaaatt catacttggc ttctaggact gaaatcatct ttgttctcag attgagatcc
     7621 attgaaacga caattcctcg gcgcttggct tcttccaaga gtaggagaag gatcgcacgg
     7681 acctcttgac cgatagctat ggtgattcca ctaaaatgaa aatggctaat cccctgaaag
     7741 agagaatcca tatctagcat gtttggccga atctggctga tactcgtatg cttacgatcg
     7801 tagaaaactt cactttgacg acaaccaaag ccgttctcca aatagtagag gccgattcga
     7861 tcgccaagcc gacagattga actggtatcg atttggtgct gtttcaagaa tgtgagaaaa
     7921 cgatctccaa tctcgttggc agggagtgcg gtaaagactt tcgttgagat acccagggct
     7981 tgcaaattac aagcgatgtt aatttctgat ccgccaaaat aagtcgaact ggcaacatga
     8041 tcgccgatac tggtggcatc taatggtgag attcgaatta atggttcgcc aaacagtaat
     8101 attttcgtca tccattagtt cctttctggt ttagaatagc tttacttggc taatacttct
     8161 ttcaaataag cagcgacttc atcatcttgg cagttttcaa agaagtattc ttggaagtat
     8221 ttgccagaga tggtgtcttt gaggaagtct tggtcgattg ttttaaggat ggtcatcaaa
     8281 tcattgtggg tgatttgttt cacctcgttt aagatacgag cgttgcgttg ttcagggatt
     8341 acacgttctc ttgggtagcc accgcccatt tcttcagcaa ataagcgttc aaacatcaat
     8401 ttgagggtca gttctgcccc ccagccaaat cctttggcat aagggataga caaggcgtta
     8461 ccaccattga tttgagaata aaggtaagcg tcagttgggt ccactgctag accacagaca
     8521 acaccaggga agctgtttaa agcaagcata gcccctacac ccgtaccaca gccggtaaca
     8581 acaaagtcaa ctgcctttgt atttaaaagg atggcagcca ttagtccgtt ctgcacataa
     8641 gttaattgac tttctccttc ttctccacgc ataccatagt taaataattg gtagcctttt
     8701 ttatctgtcg cttcttttag actatcgtaa ataatgtgat tcttgctagc ttgactattt
     8761 tcattgatta atgcgatttt cataagatct tctttctatt tttactcagg ttgttttccg
     8821 atgtaggcta agataccgcc atctacatat aggatgtggc cattgacaaa attgctggca
     8881 tcactagcga gaaagacagc agggcccatc aaatcttcag gatttcccca acgtgcagca
     8941 ggtgtttttg caatgatgaa ctggtcaaat gggtggcgag aaccatcttc ttgcaactca
     9001 cgaagaggtg ctgtttgagg agtggcaata taacccggtc caattccgtt acattggata
     9061 ttggctccac cgtattcaga cgcaatgttg cgggtcaaca ttttcaagcc ccctttagca
     9121 gcagcataag cgctaactgt ttcacgtccc agttcgctca tcatcgaaca aatattgata
     9181 atctttccat gccctttctt tatcatagaa ggaataactg cctttgaaac gataaatggt
     9241 gcgtttaagt caatatcgat gaccttacgg aaatcagcgg cgctcatttc gcacattgga
     9301 actcggcgga taataccagc gttattaacg aggatgtcaa tgacaccaac ctcttgttcg
     9361 atttgcttga ccatggcttg gataccgtcc tcgtctgtca cgtcacagac atatccatgg
     9421 gcttggatgc caacttcacg ataagcttca atccctttat tgaccagatc ttgattgata
     9481 tcgttaaaga caatagtagc gccggcttca gcgtaggatt tggcaatagc aaatccaatt
     9541 ccataagaag cgccggtgat gagagcaatt tttcctttta aagaaaactg ctcaattgag
     9601 aatgatgtat ttgtcatttg atacttcctt tcaaatttgt taagacttct ctataaccaa
     9661 attatattct agtaaaccgg ttttgtcaat aaataaatat ttttatttat aaaaagattt
     9721 attttcctta aaaatggaat attttgaaac ttctgtctat taaaatgatt aaaaagataa
     9781 tgaaagcgct aatatttttt taaaaaaact attgacaaga taaaaataaa ggattacaat
     9841 ggggaatata aagtaaaccg gtaaacctaa acaagaaagg agaaaagatg aaaattgtac
     9901 ttgtagggca tggacatttt gctacaggga tttatagttc tttacaattg attgcaggca
     9961 atcaagaaaa tgtggaggcg attgactttg tggaaggaat gtcagcagat gaactcaagc
    10021 aaaaaatctt acttgcaatt tcaaatgaag aagaagtttt aatcctaagt gatctcttgg
    10081 gaggatcgcc attcaaggtt tcttctacca taatgggaga aaatccagcc aaaacaatga
    10141 atgttctctc gggtttgaac ttagccatgt taatggaagc agtctttgct agaatggctc
    10201 atagctttga tgaggttgtt aataaatcag tagtggcggc ccagggcgga gtcgtaaatg
    10261 gtaaagaatt gttttcaacg gatgcagagg aagaggaaga agatttcgaa tcgggtattt
    10321 aaagggtaaa agaatgataa aaaaggttac gattgaaaaa ataaaatcgc ctgagcgctt
    10381 cttagaagta ccacttctga cgaaagaaga agtcggccag gcaatcgata aggttattcg
    10441 gcagttagaa ctcaaccttg actatttcaa ggaagatttc cctacgccag ctacctttga
    10501 taatgtctat ccaatcatgg ataacacgga atggaccaat ggtttctgga caggagaact
    10561 gtggttggct tatgaataca gtcaacagga tgcatttaaa aacatcgctc ataaaaatgt
    10621 tctttctttc ctggatcgtg tcaataagag agtagaattg gatcaccatg atctcggctt
    10681 cttgtacaca ccgtcttgta tggctgaata taagataaat ggagatggag aggctagaga
    10741 agcaaccttg aaagctgcag ataagttgat tgaacgctat caagaaaaag gtggttttat
    10801 tcaagcttgg ggagacttgg gcaagaaaga gcattaccgt ttgattatcg actgcttgct
    10861 caatatccaa ctcttattct ttgcttatca agaaacaggc gatcaaaaat actacgatat
    10921 tgcagaaagt catttctatg cttcagctaa taatgtaatc cgtgatgacg cttcgtcctt
    10981 ccacaccttc tattttgatc ctgagacagg tcaacccttt aaaggtgtaa cgagacaagg
    11041 gtatagtgat gattcatgct gggcacgtgg tcaatcatgg ggagtctatg gtattccttt
    11101 gacttatcgt cacttaaaag acgagtcctg ctttgacttg tttaagggtg tgaccaatta
    11161 tttcttgaat cgtctgccaa aagatcatgt gtcctattgg gatttgattt ttaatgatgg
    11221 tagtgatcaa tcacgagatt cttcagcaac agctatcgcc gtctgtggga ttcatgaaat
    11281 gctaaaacat cttccagagg tggatgctga caaagatatt tataaacatg ctatgcatgc
    11341 catgcttcgt tccttgatcg aacattatgc aaatgatcaa tttacccctg gtgggacaag
    11401 tctcctccac ggtgtgtact catggcattc aggtaaagga gtggatgaag gcaatatctg
    11461 gggtgactac tattacctag aagcccttat ccgtttctac aaagactgga acctatattg
    11521 gtaggaggag aaatatgaca atgccaaata ttattatgac ccgtatcgat gaacggttga
    11581 ttcatggaca aggacaactt tgggtaaaat acctaggttg taatacggtc attgttgcca
    11641 atgacgaagt aagcacggac aagatgcaac aaactctgat gaaaacagtt gtgccagact
    11701 cagttgccat gcgtttcttc cctttgcaaa aggtgattga tatcattcac aaggctaatc
    11761 ctgctcaaac gatctttatc gttgtaaagg atgtaaagga cgctttaacc ttggtagaag
    11821 gtggtgtccc tatcaaagaa atcaatattg ggaacattca caatgcccct ggtaaagagc
    11881 aagtgacacg ctccatcttc ctggatgaag aggacaaggc agccctcaag gaattaagcc
    11941 aaactcatca agtaacattt aatacgaaaa caactccaac aggaaatgat ggagctgttc
    12001 aagtcaacat tatggactat atttaaaaga ggagatcgtt atgtcgatta atgtatttca
    12061 agcgatttta attggattat ggacagcttt ctgttttagt ggaatgctgt taggaattta
    12121 caccaataga tgtattgttc tgtcatttgg tgtcggaatt attctaggtg atctgcctac
    12181 tgctcttgca atgggagcta ttggtgaatt ggcttatatg ggattcggtg ttggtgctgg
    12241 aggtactgtt ccaccaaacc caatcggacc tggtatcttt ggtaccttga tggctatcac
    12301 tagtgctggt aaagtcagtc cagaagcggc tcttgccctc tctactccga ttgctgtggc
    12361 gattcaattc ttacaaactt tcgcctacac tgtacgtgct ggtgcgcctg aaacggcgat
    12421 gaagcacttg aaaaaccata atttgaagaa atttaagttc actctaaatg caacaatttg
    12481 gttgtttgcc tttattggat ttaccttggg ttgcttgggt gccctttcaa tggatacctt
    12541 gttgaaactc gtagactaca ttccaccggt attgcttaca ggtttgacag ttgctggtaa
    12601 aatgctccca gctatcggtt ttgcgatgat cttgtcagtg atggctaaga aagagttgat
    12661 tccctttgtc ttgttgggat atgtttgtgc agcttatcta aacatcccaa caattggtat
    12721 tgcaattgta ggtactatct ttgctttgat tgaattttat aacaagccaa aaacagcgga
    12781 tcatgtggta gaggaggaag cacacgatga ctggatctaa caaattaaca aaacgtgatt
    12841 atcttaaaac gtctttgcgg gcattctttt gtcaaaatgg atttaactat agtaactatc
    12901 aagggttggg atatgccaat gtgatgtatc ctgctttgaa aaaacactat ggagaggatc
    12961 aggaaggttt ctaccaagcc ttggaagaaa actgtgaatt ctataatacc aatccacact
    13021 tcctgccttt tattaccagc ttgcaccttg taatgttgga aaatggccga ccaacaaaag
    13081 aaacacgtag catcaagatg gccttgatgg gaccattggc aggtattggg gattctctct
    13141 ctcaattctg tttagctcca ttgttctcaa ccatcgcagc ttcgtttgct caagaaggct
    13201 tggttgtcgg tccaatcttg ttcttccttg cgatgaatac gattttaaca gcgattaaat
    13261 tgtcaactgg tctgtatgga tacaaactag gaacaactgt gattgataaa ctaagcgaac
    13321 agatggcaac gatttctcgt attgccaata ttatcggtgt aaccgtaatt gctggtttgg
    13381 cagcgacatc tgttaagatt atggtgccga ttacctttgc tgcaggggaa gttaaagcag
    13441 acgctaaaca aagtatcgta agtattcagg gaatgcttga taaggttgct ccagctcttc
    13501 taccagccct atttacactt ttagtttact acttgatcaa agaaaagaaa tggacaacat
    13561 ataaactcgt tattttaaca gttatcatcg gaattatcgg aagctggctt aagattatag
    13621 cttaatggat acaacattgt tttatggaat agtgattgtc ttggcagtga gtcccctttt
    13681 actgtcaagc tttcattcta ttcgtcagca aaagttgctt cgcaaacaga tggagcaacg
    13741 acaagagtat ttagcttctt taacatctgg tgatgaagtg ttgttattgt ctggaattca
    13801 tggaaaaatc atttctatcc aagatgactt ggtctccttg tctatccaag atgacttggt
    13861 ctccttgcag attgcaaaag gtgtggtcat ccatgtagaa aaggaaagtg taatgggaaa
    13921 gacaaaagaa ctgcttttta agtagttctt tttctggtaa tagataatga aagaagaaag
    13981 aagaaagaag acaatttttt gaaagaatcg atggaaacca atgtcgtgat tatatcttgt
    14041 cccactgttc aaaagactat gagaaagtca agagttccct tgaacgcttg atggacaatc
    14101 gttttatgtt tgatagtcct tgggatatgg agccttgttc aaaaatccat caaatccaac
    14161 cgatggtatg ggatcaagta tttgaagatg atccagaatg ggcttatatg ctcaatcgac
    14221 aagaatatct cttgcagttt atgatagggt atatggtaga aggagataag gactatattc
    14281 aaaagtgcaa gttctttcta tttgattgga ttgagcaggt gagagaattt tctcctcaat
    14341 ccttgatgac tagaaccttg gatacgggta ttcgttcctt tacttggttg aaactactct
    14401 tgctcctctt gaaatttgac ttgctagagg agaaagaact agagaaaatt ttggtcagtc
    14461 tagaaaagca gattgacttt atgaaaagcc actatcgcgc caagtacacc cttagtaact
    14521 gggggatttt acaaacaatt ccgatgcttg ctatctatta tttcttttca gataagatgg
    14581 acctagaaga agcttaccat tttgcttcag aggagttgaa acagcaaatt gagacacaga
    14641 ttttaggaga tggaagccag tttgaacagt cgattctcta tcatgtagag gtttataaag
    14701 ccttactgga tttgtgtctc ttgcttccag acttgcaaga tagttaccga gagttgctgg
    14761 aaaagatggc gacctatatt caaatgatga caggcttaga tggacgaact ttggcttttg
    14821 gtgatagcga ttctacagaa acgacagaaa tgttgagcct gtctgctgtg gttttgaaca
    14881 aggaagacct tcttaacggt ctggatgtta aagttgattt gcttagcctc ttgttcctgg
    14941 ggcgagaaaa ggtcaagcga ctgcaggaat ttgaaaagag agcttggcag cctaagtcca
    15001 tgatctttga agactctgga catgtctgca ttaaggatga acatcgttat ctatttttca
    15061 aaaatggtcc gctaggaagt gcccatagcc atagtgacga gaatagtttt tgcttacagt
    15121 atcaaagcca acctattttc atagatgctg ggcgttattc ttatcgggag atatatgaac
    15181 gttatctctt aaagagtgct tggagtcatt cgacctgcat tgtagatggg aaagctccgg
    15241 aaagaatcac gggatcctgg gaatatgaat actatcctca ctccctgttt tgtcaccata
    15301 aagaaaggga gggagtgcat tatattgagg gggcttattg gtcagcagaa cctgatttgc
    15361 cttatcttca caagagaaaa atcctcatgt tggtagagga tgtctggctc ttggtagatg
    15421 acatcaggtg tcaaggtcag catgaggcgt tgactcagtt tatccttgac aaggatgtga
    15481 cctatcaaga tgggaaaatc aatcagttga gactatggag tgaagttgat tttgatttgg
    15541 aagataccat catttctcct aaatacaatg agcttgaaag aagtagcaaa ctcaccaagc
    15601 gccaattctt tgagaatcag atgctggatt ataccatcat tgcgcatgag agttttgaaa
    15661 tcatccgtca ttctgtctac cagacagatg atcgtgaagt ggaaaatgct ctggcttttg
    15721 aagtgaaaaa tgacgaaaca gacaagctga ttctgttatt aagcgaggat attggtgtag
    15781 gtgaaaaatt gtgcctcgtt gacggaacaa aaatgcgtgg aaaatgttta gtatatgata
    15841 aaataaatga gagaatgatt cgcttgcagt gctagaaata ggcattttga atagtgaata
    15901 tgttataata agtattagta ggaggtgttt tagattggag aagaaactga ccataaaaga
    15961 cattgcggaa atggctcaga cctcgaaaac aaccgtgtca ttttacctaa acgggaaata
    16021 tgaaaaaatg tcccaagaga cacgtgaaaa gattgaaaaa gttattcatg aaacaaatta
    16081 caaaccgagc attgttgcgc gtagcttaaa ctccaaacga acaaaattaa tcggtgtttt
    16141 gattggtgat attaccaaca gtttctcaaa ccaaattgtt aagggaattg aggatatcgc
    16201 cagccagaat ggctaccagg taatgatagg aaatagtaat tacagccaag agagtgagga
    16261 ccggtatatt gaaagcatgc ttctcttggg agtagacggc tttattattc agccgacctc
    16321 taatttccga aaatattctc gtatcatcga tgagaaaaag aagaaaatgg tcttttttga
    16381 tagtcagctc tatgaacacc ggactagctg ggttaaaacc aataactatg atgccgttta
    16441 tgacatgacc cagtcctgta tcgaaaaagg ttatgaacat tttctcttga ttacagcgga
    16501 tacgagtcgt ttgagtactc ggattgagcg ggcaagtggt tttgtggatg ctttaacaga
    16561 tgctaatatg cgtcacgcca gtctaaccat tgaagataag catacgaatt tggaacaaat
    16621 taaggaattt ttacaaaaag aaatcgatcc cgatgaaaaa actctggtat ttatccctaa
    16681 ctgttgggcc ctacctctag tctttaccgt tatcaaagag ttgaattata acttgccaca
    16741 agttgggttg attggttttg acaatacgga gtggacttgc ttttcttctc caagtgtttc
    16801 gacgctggtt cagccctcct ttgaggaagg acaacaggct acaaagattt tgattgacca
    16861 gattgaaggc cgcaatcaag aagaaaggca acaagtcttg gattgtagtg tgaattggaa
    16921 agagtcgact ttctaaaatg aaggaaaatg acttgcaatc tctgttaaga aataaaataa
    16981 tcccacctag aacaagctag gtgggattat ttgcctatga aatgagaaat tatgggagca
    17041 agctcctaaa tcaactgttt ttgatctact tctttaacta cttgataaaa gttatagaag
    17101 taggccaaac ttgaaatgat ggttacgact aggaatattg aaaatttcca ttggacaggg
    17161 ttggttaaaa gttgtggaaa ggatatgagg agaaagaaga gggctgcgtt gaggacaggt
    17221 atccgttttg attgtatttt ctcaagtcct ttattgagcg caggaagaaa gaggagtagg
    17281 agtagtaaaa ctgtatgaga aacagctcct gaaataaggg cgaagaaaag gaaaatactg
    17341 ataaaaacat gaatgatcag tagtctagct agtgatttca taaggcacct cctaatcctg
    17401 gtctttttta gctcttgcaa tacgaagtga gtcgacaata tgtatcatca ctccgaaaaa
    17461 gaaagctccc agtatagttt taaaaatatg ttttgtattt agaagagaac tgataaaatt
    17521 tggattttca cttgttaggg tatcaatgag tggaattata aaaaatatca ctgttccata
    17581 aatcgaacct gctttcagac ctggataacg taactgtctc ttttcttttt tcatagggca
    17641 cctcctaatc ctcatcttga tttttcttag tttttgcaat gcgacgggag atgaggaact
    17701 gtatgctcgc tccgaagaaa atagaaccga gaatgcttga tacaccattt cttatagtga
    17761 gaagagaatg aaaatagtcc tgaccttcac ctatgagtat cctgagaaga ggagttataa
    17821 aaaacatcca tagaccaaag aacaaacctg ctttcagacc tgggtagtgt agttgcttgc
    17881 tttctttctc attcagcata tctggttcaa tgactgtgat gcctgttttt ttcatttggt
    17941 aggtgacata gccagcagcg atgagggcaa tcactaaaat cagaggagga tagattagag
    18001 ccacttcttg agggtattta taggccagaa ggagtggaat aagatttccg aaaatcatca
    18061 gataaaagag gacgataaaa acttggttcc gaatactatc ggcctcacgc cgtttgtatt
    18121 cgtcaagggg accagaaata ccgtatgtgc gtttgatcag tttttcagtg aaggtttctt
    18181 ttttcataag tttgctcctt ttttaaaaat cttcctccca aaagagactg ttgaggtcag
    18241 tttggaggct gcgggcgaga ttgagacaga gttccaaggt tggattgtac ttgtcgtttt
    18301 caatcatatt gatagtctgt ctcgagacac cgatatcctt ggcgagttcg agctgggaaa
    18361 tacccaattc cttgcgaaat tctttcacac gattcatctg ttctcctttc tgatttatgt
    18421 cgtatatatt tgactatatt atagtctttt aaacataaag tgtcaagtat ttttgacata
    18481 ttttttgaag aaatagtagt ctccttgtcc tatttgtctg acaagtgcaa gctggtcgga
    18541 tttgtggtaa aatagataag atatgacaaa agaatttcat catgtaacgg tcttactcca
    18601 cgaaacgatt gatatgcttg acgtaaagcc tgacggtatc tacgttgatg cgactttggg
    18661 cggagcaggc catagcgagt atttattaag taaattaagt gaaaaaggcc atctctatgc
    18721 ctttgaccag gatcagaatg ccattgacaa tgcgcaaaaa cgcttggcac cttacattga
    18781 gaagggaatg gtgaccttta tcaaggataa cttccgtcat ttacaggcac gtttgcgcga
    18841 agctggtgtt caggaaattg atggaatttg ttatgacttg ggagtgtcta gtcctcaatt
    18901 ggaccagcgt gagcgtggtt tttcttataa aaaggatgcg ccactggaca tgcggatgaa
    18961 tcaggatgct agtctgacag cctatgaagt ggttaatcat tatgactatc atgacttggt
    19021 tcgtattttc ttcaaatacg gtgaggataa attctctaaa cagattgcgc gtaagattga
    19081 gcaagcgcgt gaagtgaagc cgattgagac aacgactgag ttagcagaga ttatcaagtt
    19141 ggtcaaacct gccaaggaac tcaagaagaa gggtcatcct gctaagcaga ttttccaggc
    19201 tattcgaatt gaagtcaatg atgaactggg agcggcagat gagtccatcc agcaggctat
    19261 ggatatgttg gctctggatg gtagaatttc agtgattacc tttcattcct tagaagatcg
    19321 cttgaccaag caattgttca aggaagcttc aacggttgaa gttcccaaag gtttgccttt
    19381 catcccagat gatctcaagc ccaagatgga attggtgtcc cgtaagccaa tcttgccaag
    19441 tgcagaagaa ttagaagcca ataaccgctc gcactcagcc aagttgcgcg tggccagaaa
    19501 aattcacaag taagaggaaa aaagatggca gaaagaatgg aaaaaacagg tcaaatacta
    19561 cagatgcaac ttaaacggtt ttcgcgtgtg gaaaaagctt tttacttttc cattgctgta
    19621 accactctta ttgtagcaat tagtattatt tttatgcaga ccaagctctt gcaagtgcag
    19681 aatgatttga caaaaatcaa tgcgcagata gaggaaaaga agaccgaatt ggacgatgcc
    19741 aagcaagagg tcaatgaact attacgtgca gaacgtttga aagagattgc caattcacac
    19801 gatttgcaat taaacaatga aaatattcga atagcggagt aagatatgaa gtggacaaaa
    19861 agagtaatcc gttatgcgac gaaaaatcgg aaatcgccgg ctgaaaacag acgcagagtt
    19921 ggaaaaagtc tgagtttatt atctgtcttt gtttttgccg tttttttagt caattttgcg
    19981 gtcattattg ggacgggcac tcgctttgga acagatttag cgaaggaagc taagaaggtt
    20041 catcaaacca cccgtacagt tcctgccaaa cgtgggacta tttatgaccg aaatggagtc
    20101 ccaattgctg aggatgcaac ctcctataat gtctatgcgg ttattgatga gaactataag
    20161 tcagcaacgg gtaagattct ttacgtagaa aaaacacaat ttaacaaagt tgcagaggtc
    20221 tttcataagt atctggacat ggaagaatcc tatgtaagag agcaactctc gcaacctaat
    20281 ctcaagcaag tttcctttgg agcaaaggga aatgggatta cctatgccaa tatgatggct
    20341 atcaaaaaag aattggaaac tgcagaggtc aaggggattg attttacaac cagtcccaat
    20401 cgtagttacc caaatggaca atttgcttct agttttatcg gtctagctca gctccatgaa
    20461 aatgaagatg gaagcaagag tttgctggga acctctggaa tggagagttc cttgaacagt
    20521 attcttgcag ggacagacgg cattattacc tatgaaaagg atcgtctggg caatattgta
    20581 cccggaacag aacaagtttc ccaacaaacg gtggatggca aggatgttta cacaaccatt
    20641 tccagccccc tccagtcctt catggaaact cagatggatg cctttctaga aaaagtaaaa
    20701 ggtaagtata tgaccgcgac cttggtcagt gcaaagaccg gtgaaatcct cgctaccacc
    20761 caacgaccta cctttaatgc agatactaaa gaaggaatca ctgaggactt tgtttggcgt
    20821 gatattcttt atcaaagtaa ctatgaacca ggatcagcca tgaaggttat gacgttagct
    20881 tcttctattg ataataatac cttcccaagt ggagaatact tcaatagcag tgaattcaaa
    20941 atagcggatg cgacgactcg agattgggat gttaatgatg gtttgactac tggtgggatg
    21001 atgactttct tacaaggttt cgctcactcc agtaatgttg gaatgagtct acttgaacaa
    21061 aaaatgggag atgctacttg gttggattat ctaaaacgct ttaaatttgg ggttccaact
    21121 cgctttggct tgacagatga atacgctggt caacttccag ctgataatat tgttagtatt
    21181 gctcaaagct catttgggca aggaatttca gtgacacaaa cacaaatgct tcgtgccttt
    21241 acagctattg ctaatgatgg agttatgctg gagccaaaat ttataagtgc tatttatgat
    21301 actaacaatc agtctgtacg taagtcacaa aaagaaatag taggaaatcc tgtttccaaa
    21361 gaggcagcaa gcacaactcg aaatcacatg atcttagttg ggacggaccc tctatatgga
    21421 actatgtata atcactacac aggaaagcca attataacag ttcctggaca aaatgtagca
    21481 gttaaatccg gtacggctca aatcgctgat gagaaaaatg gaggatactt ggttggttct
    21541 accaattata ttttctcagt tgtgactatg aatcctgctg aaaatcctga ttttatcttg
    21601 tatgtaacgg ttcaacagcc tgagcattat tcaggtatcc agttgggaga atttgccacc
    21661 ccaatcttgg agcgggcttc agctatgaaa gaatctctca atcttcaatc tccagccaaa
    21721 aatttagata aagttacgac agaatcttct tatgcaatgc ctagcatcaa ggatatttca
    21781 cctggtgagt tggcggaagc cttacgccga aatattgtgc aaccaatcgt tgtaggtact
    21841 ggaacaaaga ttaaagagac ttctgtagaa gaagggacca atcttgcacc aaaccaacaa
    21901 gttctccttt tatcggataa ggtagaagaa attccagaca tgtatggctg gaaaaaagag
    21961 actgccgaga cctttgctaa atggttggat attgaactgg aatttgaagg ttcaggttcc
    22021 gttgttcaga agcaagatgt tcggactaat acagctatca aaaacattaa aaaaattaaa
    22081 ttaactttag gagactaata tgtttatttc tattagtgct ggaattgtga catttttact
    22141 aactttagta ggaattccgg cctttatcca attttataga aaggcgcaaa ttacaggcca
    22201 gcagatgcat gaggatgtta aacagcacca ggcaaaagct gggactccta caatgggggg
    22261 acttgttttc ctcattgctg cagttgtggt gagtttcctc gtcgctcttt tttcgaaaca
    22321 attgaccaat aatgttggta tgattttgtt tattttggtc ttgtatggct tggttggttt
    22381 tttagatgac tttctcaagg tctttcgtaa aatcaatgag gggcttaatc ctaagcaaaa
    22441 attagctctt cagcttctag gtggagttat cttctatctt ttctatgagc gcggtggcga
    22501 tatgctttct gtctttggtt atcaagtgca tctagggatt ttctatattg tcttcgctct
    22561 tttctggcta gtcggttttt caaacgcagt aaacttgaca gacggtgttg acggtttagc
    22621 tagtatttcc gttgtgatta gtttgtctgc ctatggagtt attgcctatg tgcaaggtca
    22681 gatggatatt cttctagtga ttcttgccat gattggtggt ttgctcggtt tcttcatctt
    22741 taaccataag cctgccaagg tctttatggg tgatgtggga agtttggccc taggtgggat
    22801 gctggcagct atctctatgg ctctccacca agaatggact ctcttgatta tcggaattgt
    22861 gtatgttttt gaaacaactt ctgttatgat gcaagtcagt tatttcaaac tgacaggtgg
    22921 taaacgtatt ttccgtatga cgcctgtaca tcaccatttt gagcttgggg gattgtctgg
    22981 taaaggaaat ccttggagcg agtggaaggt tgacttcttc ttttggggag tgggacttct
    23041 agcaagtctc ctgaccctcg caattttata tttgatgtaa gaatggcacc ctgatgtttc
    23101 agggtgtttt tgtgtttaaa tacacaatga aaatcaaaga acaaactaga aagctaactt
    23161 taggctgctc aaaacatagt agtttgaaac tagaatagta cacctctact tctaaaacat
    23221 tgttagaaat cgatttgact gtcctgatcg atttgtccta tttttgtttc attttactat
    23281 acagttttga gatggctgat agaactgacg aagtcagctc aaaacaaggt tttgaggttg
    23341 tagacaaggc gaagctgatg tggtttgaag aggttttcga agagtgtaaa aaaatattgg
    23401 tcagttaaag tcaaaactct tgaccttttc tgaccaatgt agtatattat gaacgtaagg
    23461 taaatgaaag ccttactaga acacttattt aaagtaaaat agaaagaggt gggtctatgt
    23521 ttcatctagc aatcttcaga agtaaagata gtctactcct gcttgaaaaa gaaaaaccag
    23581 aaatagtacg tagggtagcg gtttagctag tctaaatttt ttaaaacaat ggtcaaagat
    23641 agtcaatatc agtaatcata actaagtaaa caaaaagagg taaagaatat gaataacaac
    23701 tttaataatt ttaataacat ggatgattta tttaaccaat tgatgggtgg tatgcgagga
    23761 tatagttctg aaaatcgccg ttacttaatt aatggacgcg aagtcacacc tgaggaattt
    23821 gctcactatc gtgcgactgg tcaattacca ggaaatgcag aaactgatgt gcaaatgcca
    23881 caacaggcat caggtatgaa acaagacggt gtccttgcaa aactaggtcg aaacttaaca
    23941 gcagaagcgc gtgagggcaa gttggatcct gttatcggac gaaacaagga aattcaagaa
    24001 acatctgaaa tcctctcacg ccgcaccaag aacaatcctg ttttggtcgg agatgcaggt
    24061 gttggtaaga cagcagttgt cgaaggtcta gcgcaagcca ttgtgaacgg agatgttcct
    24121 gctgctatca agaacaagga aattatttct attgatatct caggtcttga ggctggtact
    24181 caataccgtg gtagctttga agaaaatgtc caaaacttag tcaatgaagt gaaagaagca
    24241 gggaatatta tcctcttctt tgatgaaatt caccaaattc ttggtgctgg tagcactggt
    24301 ggagacagtg gttctaaagg acttgcggat attctcaagc cagctctctc tcgtggagaa
    24361 ttgacagtga ttggggcaac aactcaagac gaataccgta acaccatctt gaagaatgct
    24421 gctcttgctc gtcgtttcaa cgaagtgaag gtcaatgctc cttcagcaga gaatactttt
    24481 aaaattcttc aaggcattcg tgatctctat caacaacacc acaatgtcat cttgccagac
    24541 gaagtcttga aagcagcggt ggattattct gttcaataca ttcctcaacg tagcttgcca
    24601 gataaggcta ttgaccttgt cgatgtaacg gctgctcact tggcggctca acatccagta
    24661 acagatgtgc atgctgttga acgagaaatc gaaacggaaa aagacaagca agaaaaagca
    24721 gttgaagcag aagattttga agcagctcta aactataaaa cacgcatcgc agaattggaa
    24781 aagaaaatcg aaaatcatac agaagatatg aaggtgactg caagtgtcaa cgatgtggct
    24841 gaatctgtag aacgaatgac cggtattcca gtgtcacaaa tgggagcatc agacatcgag
    24901 cgtttgaaag atatggctca tcgcttgcaa gataaggtaa tcggtcaaga taaggcagta
    24961 gaagcagtgg cccgtgctat ccgtcgtaac cgtgctggtt ttgatgaagg taatcgccca
    25021 atcggtagtt tcctctttgt aggaccaact ggggttggta agacagagct tgctaagcaa
    25081 ttggcgctag atatgtttgg aaccaaggat gcgatcatcc gtttggatat gtctgaatac
    25141 agtgaccgca cagccgtttc taagctaatt ggtacaacag caggctatgt gggttatgat
    25201 gacaatagca ataccttaac agaacgtgtt cgtcgcaatc catactctat cattctcttg
    25261 gatgaaattg aaaaggctga tcctcaagtc attacccttc tcctccaagt tctagatgat
    25321 ggtcgtttga cagatggtca aggaaataca gtaaacttca agaacactgt cattattgcg
    25381 acctcaaatg ctggatttgg ctatgaagcc aacttgacag aagatgcgga caaaccagag
    25441 ttgatggatc gtttgaaacc ttacttccgt ccagaattcc ttaaccgttt caatgctgtc
    25501 atcgaattct cacacttgag caaagaagat ctttctaaga ttgtagacct tatgttggtt
    25561 gaagttaaca agacgctttc taagaaagac attgacttgg cagtgagcga agctgctaaa
    25621 gaatacatga ctgaggaagg ctacgatgaa gtcatgggtg ttcgtccact ccgtcgtgtg
    25681 gttgaacaac aaatccgtga caaagtcaca gacttccact tggataacct tgatgctaaa
    25741 cacctagaag ctgacatgga agatggtgtt ttggtcattc gtgaaaaagc ctaagacaga
    25801 attttgagca taaaaaagaa ggagccagct gaaaaactgg ttccttttga ggtacgacgg
    25861 gcatgtcgta cagtaggttg aaactagaat agtacacatc tacttctaaa atattgttag
    25921 aaatcgattt gactgtcctg attgatttgt cctgttctta tttcatttta ctatatatct
    25981 gaggtgtaag tcctcggtgg gtacctgcta ccggtgctcc caatagtgat tcccaagcct
    26041 gactatcgtg aggtagcgga ttaaaacggt ctggggatag accgttttaa gtctgacgct
    26101 ggaaataaga atcgtcagag gaagggatag cgaaatcgtg gctctacgaa taggaacgtg
    26161 ataataaggc gtatatagcg gataaggggc ctcaaactct aaagttcaaa aaggtagtcg
    26221 tagcctatat gtgtaaatca cgagagcaac tgaatttgtc tgttcgagga tggataaact
    26281 atttctcatt gggaaatatg aaaagtatag tcactagcat agatgagcgc ttgcatactc
    26341 gcctacgagt gattatctgg aagcaatgga agaagaaatc gagacgatta tggggattgc
    26401 ttaagttagg agttcctaaa tggatagcag ataaggtatc tggctggggc gaccattatc
    26461 aattagtagc tcagaagtcg gtacttaaac gtgttatatc aaaaccagtc cttgaaaaac
    26521 gtggactggt ttcgtgtttg gattattacc ttgaacgaca tgcgttaaaa gttagttgaa
    26581 ccgccgtatg ccgaacggca cgtacggtgg tgtgagaggg gctagagatt atcccctact
    26641 cgattttaaa tcacatgacg ttcaaaggca tcatctgaaa tcccttgttc caagatgagt
    26701 cttgcccatt ctttagcaga gaagaggctg tggtccttgt agtttccgca agattcgatg
    26761 gttgtccctg ggacatcttc ccaagtagta gtttcagcga tttccttgag cgaatccttg
    26821 ataacagctg cgattttagc actggtgtga cgtccccaca taatcatgtg gaagcctgtg
    26881 cgacaaccaa atggtgaaca gtcaatcatg ccgtcaatgc gggtacggat gagtttggct
    26941 aagaggtgct cgatagtgtg aaggccggca gtagggatag agtcttcgtt tggttgcacc
    27001 aagcgaatat cataattgga gatgatgtct ccttttggtc ctgtttcttc cccaatcaag
    27061 cgaacatagg gtgctttgac aatggtgtgg tcaagttcaa aactttcgac aataacttct
    27121 tttgacatgg taaatccttt cagttttctt ctctcattat atcataaagg ttgctcctga
    27181 gacagagaga aaacctctcc gaggctggag aggttgaaat ctttacttac gatataagcg
    27241 gtcgtattgg tagtatgggt caaaggttac gttgataccc agtttacgaa ggacattctt
    27301 gtcttcatca gtcaagatga tggttgagtg ggcttcgctt cctttgaggt tgccgagttc
    27361 ttccatagcg cgggcagcat caggattttc tgtagctgtg atagcaagtg caatcaggat
    27421 ttcatttgaa tgaaggcgtg gattgcggct accgagatga tcgattttaa gaccttggat
    27481 tggcttaaca acttcaggct cgattagttt tacttcttta gcgatgtcag ctgatttttt
    27541 gatggcgttg atcaaggcag cggctgtagg cccaaagagt tctgagttct taccagtgac
    27601 gatttcccca tttggcaatt caaaggctag ggctggtcca ccagtttctt ctgctttttg
    27661 gcgcgcaacg acagcaacct tacggtctgc aggtgtgata ccgaggtcgt tcatgagcaa
    27721 ctcaattttc ttgacggcag cttcgccaac tttttcagct ttgaagtcaa gaactgtttg
    27781 atagtaacgg cggatgattt cttgtttaga agcttcgaca gcagcctcgt catctgtaat
    27841 agcgaaacca accatgttga cacccatatc tgtaggtgaa gcgtatggtg attttccgag
    27901 aatacgttcc aacatgcgct tgagcactgg gaagatttcg atatcacggt tgtagttgac
    27961 agtggtttct ccataggttt gaagatggaa ggggtcaatc atgttgacat catcaaggtc
    28021 agctgtggca gcttcataag ccaagttaac tggatgatga aggggaagat tccaaacagg
    28081 gaaggtttca aatttagcgt agccagactt gatgccattg atttggtcgt ggtacatatt
    28141 ggacatacac gttgccaatt ttccagaacc gggtccagga gcggttacga caatcaagtt
    28201 gcgactggtt ttgatgtagt cgtttttgcc catgccttct ggggaaatga tgtgatccat
    28261 atccgtcgga tatcctttga ttggataatg aagataagaa tcaattccgt ttttctcaag
    28321 ttggttgcgg aaggcatctg cagcgagttg gccagcgtat tgtgtaatga caacggaacc
    28381 aacaaaaatc cctaattcat tgaatttgtc aatcaaacga agaacttctt ggtcataaga
    28441 aatgcctaag tcgccacgtg ctttggaatg ttcaatgttg ctagcattaa tggcaatcac
    28501 aacctcaacc tgctctttca attcttgcaa gagcttgatt ttgttgtcag gttcataacc
    28561 aggaaggaca cgagcagcgt ggaaatcttc taacatttta ccgccaaact ctaagtagag
    28621 cttgccgtca aattggttaa tgcgctctaa gatgtggtcg cgttgtaaat tcaaatactg
    28681 ttcagaacta aaagcttgtt ttttcatttt tttacctctg gattctatta taataaaaaa
    28741 ttggaagtta ggaaactacg gagctaaaaa agaaattaaa aagattaagc aaacgcttgc
    28801 acaaaatttt aaaaagtgct atcatatact atagattatt aaaataatga ggtaaacaga
    28861 tgcaagaaaa atggtggcat aatgccgtag tctatcaagt ctatccaaag agttttatgg
    28921 atagtaatgg agatggagtt ggtgatttgc caggtattac cagtaagttg gactatctag
    28981 ctaagctagg aatcacagcg atttggcttt ctcccgttta tgacagccct atggatgata
    29041 atggctatga tattgctgat tatcaagcga ttgcggctat ttttggaacc atggaggaca
    29101 tggatgaact gattgcagaa gctaagaagc gtgatatccg tatcatcatg gacttggtgg
    29161 tcaatcatac ctcggatgag catgcctggt ttgtagaggc ctgtgaaaat cctaatagcc
    29221 ctgagcgaga ctactatatc tggcgggatg agcctaacga tttagattct atctttagtg
    29281 ggtctgcttg ggaatacgat gaaaagtcag gtcaatacta tctccacttt ttcagcaaga
    29341 aacagccgga tctcaactgg gaaaatgaaa aacttcgcca gaaaatttat gagatgatga
    29401 acttctggat tgataagggt attggtggtt tccgtatgga tgttattgac atgattggca
    29461 aaattcctga cgagaaggta gtcaataatg gtcctatgct ccatccctat ctcaaggaaa
    29521 tgaatcaggc gacctttgga gataaggatc tcttgacagt aggggagact tggggagcaa
    29581 cgccagagat tgccaaactc tactctgatc caaaggggca agaattgtct atggtcttcc
    29641 agtttgaaca tatcggtctt cagtatcagg aaggtcagcc taaatggcac tatcaaaaag
    29701 agctgaatat cgctaagtta aaagaaatct tcaacaaatg gcagacagag ttaggagttg
    29761 aggacggctg gaattccctc ttctggaaca accatgacct ccctcgtatt gtctcaatct
    29821 ggggaaatga ccaagaatac cgcgaaaaat ctgccaaagc ctttgcaatc ttgcttcatc
    29881 ttatgagagg aactccttat atctaccaag gtgaggagat tgggatgacc aactatccgt
    29941 ttgaaacact ggatcaagta gaagatattg aatctctcaa ctatgcgcgt gaggctcttg
    30001 aaaaaggtgt tccgattgaa gaaatcatgg acagtatccg tgttattgga cgtgacaatg
    30061 cccgtacccc tatgcaatgg gacgagagca aaaacgctgg tttctcaaca ggtcaacctt
    30121 ggttggcggt taatccaaat tacgagatga tcaatgtcca agaagcgctg gcaaatccag
    30181 attctatttt ctatacctat cagaaactgg tccaaattcg caaggagaat agctggctag
    30241 ttcgagctga ctttgaattg cttgatacgg ctgataaggt ctttgcttat atacgtaagg
    30301 atggcgaccg tcgcttccta gttgtggcta acttgtccaa tgaagagcaa gacttgacag
    30361 tagaaggaaa agtcaaatct gtcttgattg aaaacactgc ggctaaagaa gtacttgaaa
    30421 aacaggtctt ggctccatgg gatgctttct gtgtggaatt actataaata ttttttgcag
    30481 aaaaatttaa aattgaaatc atgtaaaaac aagggaggac tgtataaaag acagaaatcc
    30541 tttgtttttt ataaccaagg tttataaact ttcattctcg aaattcaatt aactttacaa
    30601 attcccacta ttaaggagaa agaagatgaa cataaagaag cgtgtcctta gtgcaggtct
    30661 gacttttgca tctgctttgc tttagctgct tgcggccaat caggttcaga tacaaaaact
    30721 tactcatcaa cctttagtgg aaatccaact acatttaact atctattaga ctattacgct
    30781 gataatacag tcaattgaaa taagagcagg ataaaaaagc ctcgtaaaag gtattgcaac
    30841 ttggtaatac cttttacgag gctttttgat atgagcccat gttttctcaa taggattgta
    30901 ctcaggtgag tagggaggaa gaggtaaaag tttatgccca aactcttcgc ataaaagttc
    30961 tagcttcccc attctatgga atcttgcatt atccataata ataaccgatg gtgtggttaa
    31021 tgttggtaag aaaaacttct gaaaccatac ttcaaaaaag tcgctcgtca tcgtttcttc
    31081 gtaagtcatt ggagcgatta actcaccatt tgttagacct gcaaccaaag aaatcctctg
    31141 atat
//
LOCUS       DAVLIK010000022        30258 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLIK010000022 DAVLIK010000000
VERSION     DAVLIK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.022"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            720..1712
                     /locus_tag="VXE87_001132"
     CDS             720..1712
                     /locus_tag="VXE87_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0842684.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VXE87_001133"
     CDS             1714..2532
                     /locus_tag="VXE87_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0842685.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VXE87_001134"
     CDS             2534..3319
                     /locus_tag="VXE87_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842686.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3636
                     /locus_tag="VXE87_001135"
     CDS             3358..3636
                     /locus_tag="VXE87_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0842687.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3621..3818
                     /locus_tag="VXE87_001136"
     CDS             3621..3818
                     /locus_tag="VXE87_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0842688.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4199..4285)
                     /locus_tag="VXE87_001137"
                     /pseudo
     CDS             complement(4199..4285)
                     /locus_tag="VXE87_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4506..10937
                     /locus_tag="VXE87_001138"
     CDS             4506..10937
                     /locus_tag="VXE87_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0842689.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            11564..12040
                     /locus_tag="VXE87_001139"
     CDS             11564..12040
                     /locus_tag="VXE87_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0842690.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            12078..12383
                     /locus_tag="VXE87_001140"
     CDS             12078..12383
                     /locus_tag="VXE87_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0842691.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            12431..13906
                     /locus_tag="VXE87_001141"
     CDS             12431..13906
                     /locus_tag="VXE87_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0842692.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            13929..14006
                     /locus_tag="VXE87_001142"
                     /pseudo
     CDS             13929..14006
                     /locus_tag="VXE87_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14256..20957
                     /locus_tag="VXE87_001143"
     CDS             14256..20957
                     /locus_tag="VXE87_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0842693.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDTKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKTLRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGQTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(21205..22061)
                     /locus_tag="VXE87_001144"
                     /pseudo
     CDS             complement(21205..22061)
                     /locus_tag="VXE87_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(22272..22631)
                     /locus_tag="VXE87_001145"
     CDS             complement(22272..22631)
                     /locus_tag="VXE87_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0842694.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            22723..23679
                     /locus_tag="VXE87_001146"
                     /pseudo
     CDS             22723..23679
                     /locus_tag="VXE87_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            23663..24220
                     /locus_tag="VXE87_001147"
     CDS             23663..24220
                     /locus_tag="VXE87_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0842695.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            24213..24467
                     /locus_tag="VXE87_001148"
     CDS             24213..24467
                     /locus_tag="VXE87_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842696.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            24479..26533
                     /locus_tag="VXE87_001149"
     CDS             24479..26533
                     /locus_tag="VXE87_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0842697.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     ERIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            26712..27572
                     /locus_tag="VXE87_001150"
     CDS             26712..27572
                     /locus_tag="VXE87_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0842698.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLANYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            27783..28493
                     /gene="ccdA2"
                     /locus_tag="VXE87_001151"
     CDS             27783..28493
                     /gene="ccdA2"
                     /locus_tag="VXE87_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0842699.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            28513..29079
                     /locus_tag="VXE87_001152"
     CDS             28513..29079
                     /locus_tag="VXE87_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0842700.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            29090..30202
                     /gene="msrB"
                     /locus_tag="VXE87_001153"
     CDS             29090..30202
                     /gene="msrB"
                     /locus_tag="VXE87_001153"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0842701.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         9724 a         5255 c         6402 g         8877 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cgatgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aatttcacaa tccataggca aactcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagcaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tttccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ttggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccga aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactagatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 gttatctgca ggtcaaaaca gtggcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttacttgaca tctattctca
     3841 gagtgccata ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggagttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta tactcttaga
     4141 aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg acttcgtcag
     4201 ttctatccac aacctcaaaa cagtgttttg agcaacctgc ggctagtttc ctagtttgct
     4261 ctttgatttt cattgagtac taatcttatt ttttaacgtg tgctaaaaaa taaattaatg
     4321 catgttaatt tttcttgaat taaatttttt taaatgatat actgttttta tggagagata
     4381 acaattatat ataaatgtac tactctattt cctagataat acttagtaaa actttttata
     4441 acaaaggcta gcaaagttaa agtttattat ctattggaag ttaaataaat atgtaaggaa
     4501 ttaaaatgaa aaaaagtaca gtattgtcat taaccacagc tgcagttatt ttagcagcct
     4561 atgcccctaa tgaggtagtc ttagcagaca catctagctc tgaagatgct ttaaacattt
     4621 ctgataaaga aaaagtagta ttagataagg aaacagaaaa taaagagaaa catgaagata
     4681 ttcataatgc tatagaaact tcaaaggata ctgaagaaaa gaaaacaaca gttattgagg
     4741 aaaaagaagt tgttagtaaa aatcctgtga tagacactaa aactagcaat gaagaagcaa
     4801 gaatcaaaga agattccaat caatcccaag gagataatgc acactcgtct gcaaataaag
     4861 gcacagaaaa tccgaaaaaa gaagatagac ttgtctatat tgctgaattt aaagataaag
     4921 aatctggaga aaaagcaatc aagggactat caaatcttaa gaatacaaaa gttttatata
     4981 cttatgatag aatttttaac ggtagtgcca tagaaacaac tccagataac ttggacaaaa
     5041 ttaaacaaat agaaggtatt tcatcggttg aaagggcaca aaaagtccaa cccatgatga
     5101 atcatgccag aaaggaaatt ggagttgagg aagctattga ttacctaaag tctatcaatg
     5161 ctccgtttgg gaaaaatttt gatggtagag gtatggtcat ttcaaatatc gatactggaa
     5221 cagattatag acataaggct atgagaatcg atgatgatgc caaagcctca atgagattta
     5281 aaaaagaaga cttaaaaggt actgataaaa attattggtt gagtgataaa atccctcatg
     5341 cgttcaatta ttataatggt ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt
     5401 attttgaccc acatgggatg catattgcag ggattcttgc tggaaatgat actgaacaag
     5461 atatcaaaaa ctttaacggc atagatggaa ttgcacctaa tgcacaaatt ttctcttaca
     5521 aaatgtattc tgacgcagga tctgggtttg cgggtgatga aacaatgttt catgctattg
     5581 aagattctat caaacacaac gttgatgttg tttcggtatc atctggtttt acaggaacag
     5641 gtcttgtagg tgagaaatat tggcaagcta ttcgggcatt aagaaaagca ggcattccaa
     5701 tggttgtcgc tacgggtaac tatgcgactt ctgcttcaag ttcttcatgg gatttagtag
     5761 caaataatca tctgaaaatg accgacactg gaaatgtaac acgaactgca gcacatgaag
     5821 atgcgatagc ggtcgcttct gctaaaaatc aaacagttga gtttgataaa gttaacatag
     5881 gtggagaaag ttttaaatac agaaatatag gggccttttt cgataagaat aaaatcacaa
     5941 caaatgaaga tggaacaaaa gctcctagta aattaaaatt tgtatatata ggcaaggggc
     6001 aagaccaaga tttgataggt ttggatctta ggggcaaaat tgcagtaatg gatagaattt
     6061 atacaaagga tttaaaaaat gcttttaaaa aagctatgga taagggtgca cgcgccatta
     6121 tggttgtaaa tactgtaaat tactacaata gagataattg gacagagctt ccagctatgg
     6181 gatatgaagc ggatgaaggt actaaaagtc aagtgttttc aatttcagga gatgatggtg
     6241 taaagctatg gaacatgatt aatcctaata aaaaaactga agtcaaaaga aataataaag
     6301 aagattttaa agataaattg gagcaatact atccaattga tatggaaagt tttaattcca
     6361 acaaaccgaa tgtaggtgac gaaaaagaga ttgactttaa gtttgcacct gacacagaca
     6421 aagaactcta taaagaagat atcatcgttc cagcaggatc tacatcttgg gggccaagaa
     6481 tagatttact tttaaaaccc gatgtttcag cacctggtaa aaatattaaa tccacgctta
     6541 atgttattaa tggcaaatca acttatggct atatgtcagg aactagtatg gcgactccaa
     6601 tcgtggcagc ttctactgtt ttgattagac cgaaattaaa ggaaatgctt gaaagacctg
     6661 tattgaaaaa tcttaaggga gatgacaaaa tagatcttac aagtcttaca aaaattgccc
     6721 tacaaaatac tgcgcgacct atgatggatg caacttcttg gaaagaaaaa agtcaatact
     6781 ttgcatcacc tagacaacag ggagcaggcc taattaatgt ggccaatgct ttgagaaatg
     6841 aagttgtagc aactttcaaa aacactgatt ctaaaggttt ggtaaactca tatggttcca
     6901 tttctcttaa agaaataaaa ggtgataaaa aatactttac aatcaagctt cacaatacat
     6961 caaacagacc tttgactttt aaagtttcag catcagcgat aactacagat tctttaactg
     7021 acagattaaa acttgatgaa acatataaag atgaaaaatc tccagatggt aagcaaattg
     7081 ttccagaaat tcacccagaa aaagtcaaag gagcaaatat cacatttgag catgatactt
     7141 tcactatagg cgcaaattct agctttgatt tgaatgcggt tataaatgtt ggagaggcca
     7201 aaaacaaaaa taaatttgta gaatcattta ttcattttga gtcagtggaa gaaatggaag
     7261 ctctaaactc caacgggaag aaaataaact tccaaccttc tttgtcgatg cctctaatgg
     7321 gatttgctgg gaattggaac cacgaaccaa tccttgataa atgggcttgg gaagaagggt
     7381 caagatcaaa aacactggga ggttatgatg atgatggtaa accgaaaatt ccaggaacct
     7441 taaataaggg aattggtgga gaacatggta tagataaatt taatccagca ggagttatac
     7501 aaaatagaaa agataaaaat acaacatccc tggatcaaaa tccagaatta tttgctttca
     7561 ataacgaagg gatcaacgct ccatcatcaa gtggttctaa gattgctaac atttatcctt
     7621 tagattcaaa tggaaatcct caagatgctc aacttgaaag aggattaaca ccttctccac
     7681 ttgtattaag aagtgcagaa gaaggattga tttcaatagt aaatacaaat aaagagggag
     7741 aaaatcaaag agacttaaaa gtcatttcga gagaacactt tattagagga attttaaatt
     7801 ctaaaagcaa tgatgcaaag ggaatcaaat catctaaact aaaagtttgg ggtgacttga
     7861 agtgggatgg actcatctat aatcctagag gtagagaaga aaatgcacca gaaagtaagg
     7921 ataatcaaga tcctgctact aagataagag gtcaatttga accgattgca gaaggtcaat
     7981 atttctataa atttaaatat agattaacta aagattaccc atggcaggtt tcctatattc
     8041 ctgtaaaaat tgataacacc gcccctaaga ttgtttcggt tgatttttca aatcctgaaa
     8101 aaattaagtt gattacaaag gatacttatc ataaggtaaa agatcagtat aagaatgaaa
     8161 cgctatttgc gagagatcaa aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag
     8221 tttggtatgc tggcgccgct cttgttaatg aagatggaga ggttgaaaaa aatcttgaag
     8281 taacttacgc aggtgagggt caaggaagaa atagaaaact tgacaaagac ggaaatacca
     8341 tttatgaaat taaaggtgcg ggagatttaa ggggaaaaat cattgaagtc attgcattag
     8401 atggttctag caatttcaca aagattcata gaattaaatt tgctaatcag gctgatgaaa
     8461 aggggatgat ttcctattat ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc
     8521 ttggcgagat tgcagaatct aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa
     8581 aaaaagatac aactggggta gaacatcatc atcaagaaaa tgaagagtct attaaagaaa
     8641 aatctagttt tactattgat agaaatattt caacaattag agactttgaa aataaagacc
     8701 taaagaaact cattaaaaag aaatataagg aagaagacga ctttgtaact ggtggaaaaa
     8761 gaacagtaga acttgattat aaatatgacg ataaaggaaa tataactgcc tatgaagatg
     8821 aaagtgctct agaatatgaa actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg
     8881 ttctaagccc atctaaagat ggacactttg aaattcttgg aaagataagc aatgtttcta
     8941 aaaatgccaa ggtatattat ggaaataact ataaatttat agaaatcaaa gcgactaagt
     9001 atgactcaca ttcaaaaacg atgacatttg atttatacgc taatattaat gatattgtgg
     9061 atggattagc ttttgctgga gatatgcggt tttttgttaa agatgatgat cgaataaaag
     9121 ctgaaactaa aattagaatg cctgaaaaaa ataaggaaac taaagcagaa tatccctatg
     9181 tatcaagtta tgggaatgta atcgaattag gagaaggaga tctttcaaag aacaaaccag
     9241 acaatttaac taaaatggaa tctggtaaaa tctattctga ttcagaaaaa caacaatatc
     9301 tgttaaagga taacatcatt ctaagaaaag gctatgcact aaaagtgact acctataatc
     9361 ctggaaaaac ggatatgtta gaagggaatg gagtctatag caaggaagat atagcaaaaa
     9421 tacaaaaggc caatcctaat ctaagagtcc tttcagaaac aacaatttat gctgatagta
     9481 gaaatgttga agatggaaga agtacccaag ctgtattaat gtcggctttg gacggcttta
     9541 acattataag gtatcaagtg tttacattta aaatgaacga taaaggggaa gctatcgata
     9601 aagacggaaa tcttgtgaca gattcttcta aacttgtatt atttggtaag gatgataaag
     9661 aatacactgg agaggataag tccaatgtag aagctataaa agaagatggc tccatgttat
     9721 ttattgatac caaaccagta aacctttcaa tggataagaa ctactttaat ccatctaaat
     9781 ctaataaaat ttatgtacga aatccagaat tttatttaag aggtaagatt tctgataagg
     9841 gtggttttaa ctgggaattg agagttaatg aatcggttgt agataattat ttaatctacg
     9901 gagatttaca cattgataac actagagatt ttaatattaa gttgaatgtt aaagacggtg
     9961 acatcatgga ctggggaatg aaagactata aagcaaacgg atttccagat aaggtaacag
    10021 atatggatgg aaatgtttat cttcaaactg gctatagcga tttgaatgct aaagcagttg
    10081 gagtccacta tcagttttta tatgataatg ttaaacccga agtaaacatt gatcctaagg
    10141 gaaatactag tatcgaatat gctgatggaa aatctgtagt ctttaacatc aatgataaaa
    10201 gaaataatgg attcgatggt gagattcaag aacaacatat ttatgtaaat ggaaaagaat
    10261 atacatcatt tgatgatatt aaacaaataa cagacaagac actaaacatt aagattgttg
    10321 taaaagattt tgcaagaaat acaaccgtaa aagaattcat tttaaataaa gatacgggag
    10381 aggtaagtga attaaaacct catagggtaa ctgtgaccat tcaaaatgga aaagaaatga
    10441 gttcaacgat agtgtcggaa gaagatttta ttttacctgt ttataagggt gaattagaaa
    10501 aaggatacca atttgatggt tgggaaattt ctggtttcga aggtaaaaaa gacgctggct
    10561 atgttattaa tctatcaaaa gataccttta taaaacctgt attcaagaaa atagaggaga
    10621 aaaaggagga agaaaataaa cctacttttg atgtatcgaa aaagaaagat aacccacaag
    10681 taaaccatag tcaattaaat gaaagtcaca gaaaagagga tttacaaaga gaagatcatt
    10741 cacaaaaatc tgattcaact aaggatgtta cagctacagt tcttgataaa aacaatatca
    10801 gtagtaaatc aactactaac aatcctaata agttgccaaa aactggaaca gcaagcggag
    10861 cccagacact attagctgcc ggaataatgt ttatagtagg aatttttctt ggattgaaga
    10921 aaaaaaatca agattaagat aaaagctata gaaaaaaatg gtttatgtac tgagattaga
    10981 tagtgaggtg atgacatagt tttgtgaaaa cagccattta taactcaatt atttagttta
    11041 cttcactatt gatactattt ggagttatta atggacttag tttagataac taatgaattg
    11101 attgaaaggg ttagtattga caatattggt catattgatt agaaaataga gtctatcaaa
    11161 atttaaaggc taatagaggt gatgagacaa tttcaaggaa ttaagtagcg tttggttgct
    11221 taattccttt ttatttggaa ggaagttttt cgtaaccgcc caataacgaa gtctattggg
    11281 cggttacgat atgatcactg acttcgtcag ttctatctac aacctaaaaa cagtgttttg
    11341 aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgaatat tagaacagca
    11401 aaaatgcttg gagtatttgt ttgtgtgttt gtttttatat aacaaactat aaacaaaaca
    11461 aaaatataaa aaaagagaca aaaaagaaca aaaagtaatt gacaacggtt tcatatagtg
    11521 ttatacttat ggcataaagt taatggaaag aagggaaaac cttatggtat tagattattt
    11581 ctttgacaaa aaccttgtgt tttgcttaga agcggataat caagaacaac tctttgatca
    11641 ggttgcaact ttattggaag aacgagaaat tgtcactcca acttatcgtg aagccttgat
    11701 cacgcgtgaa aagtcatttc caactggttt agatatggaa tttctaggaa aggacttgcc
    11761 aaatgtagcg attcctcata cagatattgt tcataatcta gctgagaaag tggtggttgt
    11821 tcgattagaa aaaccagtaa cttttcacaa tatgatagct cctgataagg aagtagaagt
    11881 atccttgctc ttctttatca tcaataactc aagttcaagt caaacaaata ttctggctca
    11941 gttgatggac tttttcacag gaaatggaca tcttgaagac ctatcaaaaa tttccgaacc
    12001 agaaaaactt tatgcttaca ttgctgaagc aaccgcttaa tcttgtctat taaaaaataa
    12061 aatcggagga aatctaaatg attaaaattc ttgctgcctg cggtgcaggt gttaactcaa
    12121 gtcaccaaat taaaagtgct ctagaagaag aactttcaaa ccgtggttat gatgttcact
    12181 gtgatgcagt catggtgaaa gatgtaaacg aagaccttat gaaaggttac gatatcttta
    12241 caccaatcgc tgcaacagac cttggttttg aaccaggtat cccagttatc gaagctggac
    12301 caatcttatt ccgtatccca gcaatgagcg ctccagtatt tgacaatatt gaagcagcta
    12361 ttaaagaaca cggattaagc taattctaat ttgttaacat tcatataaca taaaaaaggg
    12421 aggaactgtt atggatgcaa tctttgacct aatcggaaag gttttcaatc ccatcttaga
    12481 aatgggtgga cctgtcatca tgttaatcat tttgacagta ttggctttac tttttggagt
    12541 gaaattctcc aaagcgcttg aaggtggtat caaacttgcc atcgctctta caggtatcgg
    12601 tgctatcatc ggtatgctaa atggtgcttt ctcagcatca cttgcaaaat tcgttgaaaa
    12661 cactggtata caattgagta ttaccgacgt tggttgggca ccacttgcaa caatcacttg
    12721 gggttctgct tggacacttt acttcttgct catcatgttg attgtcaacg tagtgatgct
    12781 tgctatgaag aaaaccgata cacttgatgt cgatatcttt gatatctggc acttgtctat
    12841 cacaggtctt ttgattaaat ggtatgctga taacaatggt gtgagtcaag gggtttcact
    12901 cttgattgct acagcagcta tcgttcttgt cggtgtgttg aaaattatca actctgactt
    12961 gatgaaacct acatttgatg accttcttaa cgccccaagt tcatcaccaa tgacatcaac
    13021 tcacatgaac tacatgatga acccagttat catggttttg gataagattt ttgaaaaatt
    13081 cttcccaggc cttgataaat atgactttga tgctgctaaa ttgaacaaga aaatcggttt
    13141 ctggggatct aaattcttca tcggtttcat ccttggtatc gttatcggta ttatgggaac
    13201 tccacatcca attgcaggtg ttgcagatgc agataaatgg cgtcttgtta tcaaaggatg
    13261 gttgtctctt ggtttgactg ccggtgtatc tttggaactc ttctcactta tcggttcatg
    13321 gttcatcgca gccgtagaac cactatcaca aggtattaca aacgttgcta ctaaacgtct
    13381 tcaaggacgt aaattcaata tcggtcttga ctggccattc atcgctggtc gtgctgaaat
    13441 ctgggcttgt gccaacgtac ttgcaccaat catgttgatt gaagcagtgc ttctttcaaa
    13501 agttggaaat ggtatcttgc cacttgcagg tatcatcgct atgggtgtta ctccagctct
    13561 cttggttgta actcgtggta aattgctccg tatgattatc ttcggaacac tcttgttgcc
    13621 actcttcctt ctttcaggta cacttattgc accatttgca acagaacttg ctaaaggtgt
    13681 aggtgccttc ccagaaggtg tgagccaaac tcaattgatt actcactcta ctcttgaagg
    13741 accaatcgaa aaacttcttg gttggacaat tggtaacact acaactggtg atatcaaagc
    13801 aatccttggt gcagtagcct tccttgtatt ctatatcggt atctttgctt ggtacagaaa
    13861 acaaatgatc aaacgtaacg aagagtacgc agcaaaagca aaataatgcg ctcctataaa
    13921 atataaactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac
    13981 acagttttga ggttgtagat aagactgacg aagtcagctc aaaacatggt tttgaggttg
    14041 tagatgaaac tgacgaagtc agctcaaaac atggttttga ggttgtagat gaaactgacg
    14101 aagtcagtaa tcatatctac ggcaaggcga cactgacgaa gtttgaattg gattttcgca
    14161 gagtgtaaat tgttgaaact aggttgtcat accatgtata ccacttgggc tttggtagta
    14221 gctaactgca ctaaatataa tataaggagg gttttatggg gaaaggccat tggaatcgga
    14281 aaagagttta tagcattcgt aagtttgctg tgggagcttg ctcagtaatg attgggactt
    14341 gtgcagttct attaggagga aatatagctg gagaatctgt agtttatgcg gatgaaacac
    14401 ttattactca tactgctgag aaacctaaag aggaaaaaat gatagtagaa gaaaaggctg
    14461 ataaagcttt ggaaactaaa aatgtagttg aaaggacaga acaaagtgaa cctagttcaa
    14521 ctgaggctat tgcatctgag aagaaagaag atgaagccgt aactccaaaa gaggaaaaag
    14581 tgtctgctaa accggaagaa aaagctccaa ggatagaatc acaagcttca agtcaagaaa
    14641 aaccgctcaa ggaagatact aaagctgtaa caaatgaaga agtgaatcaa atgattgaag
    14701 acaggaaagt ggattttaat caaaattggt actttaaact caatgcaaat tctaaggaag
    14761 ccattaaacc tgatgcagac gtatctacgt ggaaaaaatt agatttaccg tatgactgga
    14821 gtatctttaa cgatttcgat catgaatctc ctgcacaaaa tgaaggtgga cagctcaacg
    14881 gtggggaagc ttggtatcgc aagactttca aactagatga aaaagacctc aagaaaaatg
    14941 ttcgccttac ttttgatggc gtctacatgg attctcaagt ttatgtcaat ggtcagttag
    15001 tggggcatta tccaaatggt tataaccagt tctcatacga tatcaccaaa taccttcaca
    15061 aagatggtcg tgagaatgtg attgctgtcc atgcagtcaa caaacagcca agtagccgtt
    15121 ggtattcagg aagtggtatc tatcgtgatg tgactttaca agtgacagat aaggtgcatg
    15181 ttgagaaaaa tgggacaact attttaacac caaaacttga agaacaacaa catggcaagg
    15241 ttgaaactca tgtgaccagc aaaatcgtca atacggacga caaagaccat gaacttgtag
    15301 ccgaatatca aatcgttgaa cgaggtggtc atgctgtaac aggcttagtt cgtacagcga
    15361 gtcgtacctt aaaagcacat gaatcaacaa gcctagatgc gattttagaa gttgaaagac
    15421 caaaactctg gaccgtttta aatgacaaac ctgccttgta cgaattgatt acgcgtgttt
    15481 accgtgacgg tcaattggtt gatgctaaga aggatttgtt tggttaccgt tactatcact
    15541 ggactccaaa tgaaggtttc tctttgaatg gtgaacgtat taaattccat ggagtatcct
    15601 tgcaccacga ccatggggcg cttggagcag aagaaaacta taaagcagaa tatcgccgtc
    15661 tcaaacaaat gaaggagatg ggagttaact ccatccgtac aacccacaac cctgctagtg
    15721 agcaaacctt gcaaatcgca gcagaactag gtttactcgt tcaggaagag gcttttgata
    15781 cttggtatgg tggcaagaaa ccttatgact atggacgttt ttttgaaaaa gatgccactc
    15841 acccagaagc tcgaaaaggt gaaaaatggt ctgattttga cctacgtacc atggtcgaaa
    15901 gaggcaaaaa caaccctgct atcttcatgt ggtcaattgg taatgaaata ggtgaagcta
    15961 atggtgatgc ccactcttta gcaactgtta aacgtttggt caaggttatc aaggatgttg
    16021 ataagactcg ctatgttacc atgggagcag ataaattccg tttcggtaat ggtagcggag
    16081 ggcatgagaa aattgctgat gaactcgatg ctgttggatt taactattct gaagataatt
    16141 acaaaaccct tagagctaag catcccaaat ggttgattta tggatcagaa acatcttcag
    16201 ctacccgtac acgtggaagt tactatcgcc ctgaacgtga attgaaacat agcaatggac
    16261 ctgagcgtaa ttatgaacag tcagattatg gaaatgatcg tgttggttgg gggaaaacag
    16321 caaccgcttc atggactttt gaccgtgaca acgctggcta tgctggacag tttatctgga
    16381 caggtacgga ctatattggt gaacctacac catggcacaa ccaaaatcaa actcctgtta
    16441 agagctctta ctttggtatc gtagatacag ccggcattcc aaaacatgac ttctatctct
    16501 accaaagtca atgggtttct gttaagaaga aaccgatggt acaccttctt cctcactgga
    16561 actgggaaaa caaagaatta gcatccaaag tagctgactc agaaggtaag attccagttc
    16621 gtgcttattc gaatgcttct agtgtagaat tgttcttgaa tggaaaatct cttggtctta
    16681 agactttcaa taaaaaacaa accagcgatg ggcagactta ccaagaaggt gcaaatgcta
    16741 atgaacttta tcttgaatgg aaagttgcct atcaaccggg taccttggaa gcaattgctc
    16801 gtgatgaatc tggcaaggaa attgctcgag ataagattac gactgctggt aagccagcgg
    16861 cagttcgtct tattaaggaa gaccatgcga ttgcagcaga tggaaaagac ttgacttaca
    16921 tctactatga aattgttgac agccagggga atgtggttcc aactgctaat aatctggttc
    16981 gcttccaatt gcatggccaa ggtcaactgg tcggtgtaga taacggagaa caagccagcc
    17041 gtgaacgcta taaggcgcaa gcagatggtt cttggattcg taaagcattt aatggtaaag
    17101 gtgttgccat tgtcaaatca actgaacaag cagggaaatt caccctgact gcccactctg
    17161 atctcttgaa atcgaaccaa gtcactgtct ttactggtaa aaaagaagga caagagaaga
    17221 ctgttttggg gacagaagta gcaagagttc gtacattaat tggtaaagaa ccaaaaatgc
    17281 cgaaaacagt aggttttgta tacagcgatg gtagtcgtga aaaacttcca gtaacttggt
    17341 ctcaagtcga tgttagtcaa gcaggagttg tgactgttaa aggtacagca aatggacgtg
    17401 aggtagaggc tcatgtcgag gttctagcaa ttgcgaaaga attaccaaca gttaaacgta
    17461 ttgctccaaa tactgacttg aattctgtag acaaatctgt ttcttatgtt ttgactgatg
    17521 gaagtgtaca agagtacgaa gtagatagct gggagattac ggaagtagat aaagccaaac
    17581 tttcagtagc tggatcacgt attcaaatga ctggtcagtt agctggagaa actattcatg
    17641 caacccttgt ggtagaagaa ggaaatgctg cagcacctgt agtgccaact gttactgttg
    17701 gaggtgaggc agtaacaggt cttactagtc gacaaccaat gcaatatcgt actctatctt
    17761 atggtgccca actgccagaa gtcacagcaa gtgctgaaaa tgctgatgtg acagttcttc
    17821 aagcaagcgc agcaaacggc atgcgtgcga gcatctttat tcagcctaaa gatggtggtc
    17881 ctcttcaaac ctatgcaatt caattccttg aagaagcgcc aaaaattgct cacttgagtt
    17941 tgcaagtgga aaaagctgac agtctcaaag aagaccaaac tgtcaaattg tcggttcgag
    18001 ctcactatca agatggaacg caagctgtat taccagctga taaagtaacc ttctctacaa
    18061 gtggtgaagg ggaagtcgca attcgtaaag gaatgcttga gttgcataag ccaggagcag
    18121 tcactctcaa agcggaatat gagggagcta aaggccaagt tgaactcact atccaagcca
    18181 atactgagaa gaagattgcg caatctatcc gtcctgtaaa tgtagtcaca gatttgcatc
    18241 aaaaacctac tcttccaaca acagtaacgg ttgagtatga caaaggtttc cctaaagctc
    18301 acaaagtcac ttggcaagct attccgaaag aaaaactaga ctcctatcaa acatttgaag
    18361 tactaggtaa agttgaagga attgaccttg aagcgcgtgc aaaagtctct gtagaaggta
    18421 tcgtttcagt tgaagaagtc agtgtgacaa ctccaatcgc agaagcacca caattaccag
    18481 aaagtgttcg gacatatgat tcaaatggtc acgtttcatc agctaaggtt gcatgggatg
    18541 cgattcgtcc agagcaatac gctaaggaag gtgtctttac agttaatggt cgcttagaag
    18601 gtactcaatt aacaactaaa cttcatgttc gcgtatctgc tcaaactgag caaggtgcaa
    18661 acatttctga ccaatggacc ggttcagaat tgccacttgc ctttgcttca gactcaaatc
    18721 caagcgaccc agtttcaaat gttaatgaca agctcatttc ctacaataac caaccagcca
    18781 atcgttggac aaactggaat cgtactaatc cagaagcttc agtcggtgtc ctattcggag
    18841 attcaggtat tttgagcaaa cgttcagttg ataacttaag cgttggcttc catgaagacc
    18901 atggagttgg tgcaccgaag tcttatgtga ttgagtatta tgttggtaag actgtcccaa
    18961 cagctcctaa aaaccctagt tttgttggta atgaggacca tgtctttaat gattctgcca
    19021 actggaaacc agttactaat ctaaaagccc ctgctcaact caaggctgga gaaatgaacc
    19081 actttagctt tgataaagtt gaaacctatg ctgttcgtat tcgcatggtg agagcagaca
    19141 acaaactagg aacgtctatc acagaggtac aaatctttgc gaaacaagtt gcggcagcca
    19201 agcaaggaca aacaagaatc caagttgacg gtaaagactt agcaaacttc aaccctgatt
    19261 tgacagacta ctaccttgag tctgtagatg gaaaagttac ggcagtcaca gcaagtgtta
    19321 gcaacaatgg cctcgctacc gtcgttccaa gcgttcgtga aggtgagccg gttcgtgtca
    19381 tcgcgaaagc tgaaaatggc gacatcttag gagaataccg tctgcacttc actaaggata
    19441 agaacttact ttctcataaa ccagttgctg cggttaaaca agctcgcttg ctacaagtag
    19501 gtcaagcact tgaattgccg actaaggttc cagtttactt cacaggtaaa gacggctacg
    19561 aaacaaaaaa cctgacagtt gaatgggaag aagttccagc ggaaaatctg ataaaagcag
    19621 gtcaatttac cgttcgaggc catgtccttg gtagtgatct tgttgctgag gtcactgtac
    19681 gagtgacaga caaactaggc gaagctcttt cagataaccc taactatgat gaaaacagta
    19741 accaggcctt tgcttcagca accaatgata ttgacaaaaa ctctcatgac cgcgttgact
    19801 atctcaatga cggagatcat tcagaaaatc gtcgttggac aaactggtct ccaacaccat
    19861 cttctaatcc agaagtatca gcgggtgtga tcttccgtga aaatggtaag attgtagaac
    19921 ggactgttgc tcaagccaaa cttcacttct ttgcagatag tggtacggat gcaccaacta
    19981 aactcgtttt agaacgctat gtcggtccag agtttgaagt gccaacctac tattcaaact
    20041 accaagccta cgacgcagac catccattca acaatccaga aaattgggaa gctgtgcctt
    20101 atcgtgcgga taaagacatc gcagctggtg atgaaatcaa cgtaaccttt aaagctgtca
    20161 aagccaaagc tatgagatgg cgtatggagc gtaaagcaga taagagcggt gttgcgatga
    20221 ttgagatgac cttcctggca ccgagtgaat tgcctcaaga aagcacgcaa tcgaagattc
    20281 ttgtagatgg aaaagaactt gctgatttcg ctgaaaatcg tcaagactat caaattacct
    20341 ataaaggtca acggccaaaa gtctcagttg aagaaaacaa tcaagtagct tcaactgtgg
    20401 tagatagtgg agaagatagc cttccagtac ttgttcgcct cgtttcagaa agtggaaaac
    20461 aagtcaagga ataccgtatc cagttgacta aggaaaaacc agtttctgag aagacagttg
    20521 ctgctgtaca agaagatctt ccaaaactcg aatttgttga aaaagatttg gcctacaaga
    20581 cagttgagaa aaaagattca acactgtatc taggtgaaac tcgtgtagaa caagaaggaa
    20641 aaactggtaa agaacgtatc tttacagcga ttaatcctga tggaagtaag gaagaaaaac
    20701 tccgtgaagt ggtagaagct ccgacagacc gcatcgtctt ggttggaacc aaaccagtag
    20761 ctcaagaagc taaaaaacca caagtgtcag aaaaagcaga tacaaaacca attgattcaa
    20821 gtgaagctag tcaaactaat aaagcccagt taccaaatac aggtagtgcg gcaagccaag
    20881 cagcagtagc agcaggttta gctcttctag gtttgagtgc aggattagta gttactaaag
    20941 gtaaaaaaga agactagaaa ttttgatacc ttctttatca ttaaagacca aagaaaaact
    21001 cttgtcctaa atagaagata aagagtctgg aacaaaatag ttctcaacca caaaaaagct
    21061 agatatttcc aattgcggaa ctctagcttt ttaattttga gtcgttctct tattgtatag
    21121 tagattgaaa ctagagtagt acacttctac ttctaaaaca ttgttagaaa tcgatttgac
    21181 tgtccttatc gatttgtcct gttcttattt catttcacta tgttttagga ggttattggc
    21241 cataagtacc aatcccatgt caattctcac ttgacgcttg cctctcagat tacatctctt
    21301 gtaacccaaa caagccttta tctgcccaaa gacaggttct acatcaatct tgcgttgagc
    21361 gaaaatctgt ctatcttggg gagataaaag cgcctgacat tctttagctt tcaagttttg
    21421 atagcgttcg ttcatataca atcccttttg aggggctgat tcaggttcat cagcgtagta
    21481 aaccttgatt tcctgttgaa agtctgtctg tgttttctgg tacttgatat ggtgaaaacg
    21541 atagcaccag ccatcaggat gtatgtagct atcctccttg tcattatagt gccaattcgc
    21601 taagttttta gctgactgtt tataccctct cttttgttcc ttatcaaaca tggcatattt
    21661 aatcagaagg ggagtgattt cttcttgaaa atagacttgt atctgttctt gaagtttggc
    21721 ggagaatttc tctgtcgttt tcttccacac aaaactatac ttgttggcat tggattcaat
    21781 cttagttccg tcaataaaca aacaatctaa ggtcactaac tcttccattt ttcaattttt
    21841 cgaccagaga aaatcccttg tgaataggca aatagaagag tagatacaag cattttaggg
    21901 tgataagacg ggcgaccaaa ggcatgatag gaggtgtaga agtgacgttc ctccaaggta
    21961 ttcaccactt tttcaatagt aaagacgaga tggtcttgtg gtaagaagga actgatttct
    22021 agtggtaaag ttgtttgatt tgtgttatag tgaatatgca tgggatagcc tttctaaatg
    22081 gtttattaag caattctatt ttaccaagac tatcgtaacc atgcaaaaaa gcaacggcaa
    22141 atccgttgcc ttttttggat ataagagact attgtcccag actcttttct ttgtataaaa
    22201 ttgtatagtg ttattgtcta tactattttg tagagaaagc aaaaatccct agaaaatgct
    22261 tagggattcg actatttcat taagaacaat tcaacaatca tctctatata catgataagg
    22321 gttaataaaa atcctgtacg ccagaagaat ttgatgaatt taggatagta aaagctgcgt
    22381 ttttttaaaa ggaagaaaaa gacgagaata atggctagga acgagagggc tagccccagt
    22441 ctagggagga aattatgggt aaaggtttta gctgtaatca agtaatactc aaataccaag
    22501 actggaaaag ccaaatccgc aaagtttcgt cctagttttt ttaatctaaa aagtttggtt
    22561 aggataatgc agacgactaa ggtcagtatc aataataaaa tagatgctaa tttcattaaa
    22621 atcataccca tattgtatca taaaaaaagg ctaatggaaa cgagaaacag aggaatttat
    22681 aggaaagtca ggcttttgag attgtgggtg atttttgtta taatgaaagt tataaaatct
    22741 tatgatacct tgaatgatta ttatcgaaaa ctctttggag aaaagacttt taaagtccct
    22801 attgatgcgg gatttgactg tcccaatcgt gatggaactg tggctcatgg aggctgtact
    22861 ttttgtacgg tttccggttc tggagatgcc attgtagccc cagatccgcc tatccgtgag
    22921 caattttata aggaaattga ctttattcat cgtaagtggc cagatgttca gaagtatctg
    22981 gtttattttc aaaattttac caacacccat gaaaaggtgg aagttattcg agagcgttat
    23041 gaacaggcta tcaatgagcc aggtgtggta ggaatcaata ttggaacgcg cccagactgt
    23101 ttaccagacg aaaccatcga atatttggct gagttatcgg agtgcatgca tgtgacggtt
    23161 gaattgggct tgcagactac ttatgaagca acctctgacc tgattaaccg tgcgcattct
    23221 tatgaattgt aggtggaaac ggtcaagcgt ttgagaaagt atccaaaaat tgagattgtt
    23281 tcccatttga tcaatggttt gcctggtgaa acccatgaga tgatggttga aaatgtccgc
    23341 cgttgtgtca cggataacga tattcaaggg attaaactgc atttgctcca tcttatgaca
    23401 aatactcgta tgcaacgaga ttaccatgag ggacgtttac aattgatgag tcaggacgaa
    23461 tatgtcaggg tcatctgtga ccaactggaa attattccca aacatatcgt catccatcga
    23521 attacaggag atgcgcctag ggatatgctg attggtccta tgtggagcct caataaatgg
    23581 gaagtcctca acagcattga gatggagatg agacgtcgtg gaagtgttca aggatgcaag
    23641 gctgtaaaac aggagtttga aaatgaaaag accacttgag atggcacatg attttttggc
    23701 tgaggtcgtg acaaaagagg atgtcgtagt ggatgcgact atgggaaatg gtcatgacac
    23761 gcttttttta gccaagctag ccaagcaagt ctatgccttt gatattcaga agcaagcctt
    23821 ggaaaagacc caagagcgtt tgcatcaggc tggcttgaca aatgcccagt taatcttgca
    23881 aggccatgag acactggacc agtttgtgac aaaagctaag gcagggattt ttaatttggg
    23941 ctatttgccg tcagctgata agtctgtcat cacccgaccg cagacaacga ttgaggcatt
    24001 agaaaagcta tgtggcttac ttgtcaaagg tggacgaatt gctattatga tttactatgg
    24061 tcatgaagga ggcgacctcg agagagatgc tgtcttggat tttgtgatcc agttgaacca
    24121 acaagagtac acagctgcca tttaccgaac tttaaaccaa gtcaacaacc cgccgttttt
    24181 agtgatgatt gaaaaattag agagatacag acatggataa acaataccta cacgaaaagc
    24241 tggatgccat gcgccagaat tttgttgaat caacctacca cgaacgagcg gtgggcgtgc
    24301 tagaccaagc gcatatgagc aaaaaaatgc ttaaaatcaa gaaaaaatta gttgctcttg
    24361 aaatggaacg gtgccagaga aaaattgagc acaaagactg ttccaagatt gaccaaaaaa
    24421 tcaaagagca gaaggagata tttgaatcct gttgtaaaaa agattaagga ggacgtgcgt
    24481 ggaattactg atttacctca tcctattttt actggtcttg attgtctcaa gtacaaccaa
    24541 taagctccta ccctttttgc ctctcccttt ggtgcagatt cttttgggaa ttgtgattgg
    24601 tctcttttta cccaatactg actttcacct taatacggag ttgtttttgg cactggttat
    24661 cggccccttg cttttccgag aggctgaaga agcagatgtt acggctattt taaaacactg
    24721 gcgaatcatt gtttatctca tatttccagt gatttttatc tcgaccctga gtttgggtgg
    24781 cttggcccat cttctttggt tcagccttcc cttggcagct tgcttggctg ttggggcagc
    24841 ccttggtcct acggacttgg tggcctttgc ctctctttcg gagcgtttta gctttcctaa
    24901 gcgcgtgtcc aatattctta agggcgaagg actcttgaat gatgcttctg gtttggtggc
    24961 ttttcaggta gctttgacag cttggacaac tggagctttt tctctggggc aagctagcag
    25021 ttcactcatc ttttcaatcc taggcggttt tttaattgga tttttaacag ccatgaccaa
    25081 ccgcttcctc cataccttct tgctaagtgt gcgtgcaacg gatattgcca gtgaactttt
    25141 attagaattg agtttgcctc ttgtgacctt ctttctggca gaagaagttc atgtttcagg
    25201 tattattgcc gtcgtagttg ctggaatttt aaaggcaagt cgtttcaaga aaatcacgct
    25261 cctcgaagcc caagtggata cggtgaccga gacggtctgg catacagtga cctttatgct
    25321 caacggttct gtctttgtga ttttagggat ggagctggaa atgatagcag aacctatctt
    25381 gaccaatcca atctataatc ctctactttt attgctatct cttatcgccc ttacctttgt
    25441 cctctttgtc attcgtttta ttatgatcta tggctattat gcctatagaa cccgacgcct
    25501 caagaaaaag ctaaataagt atatgaagga catgtttctc ttgacctttt caggtgttaa
    25561 gggaacggtg tcgattgcta cgattctctt gataccaagt aatctagaac aggagtatcc
    25621 tctcttgctt ttccttgttg caggtgtgac gcttgttagc tttttaacag gtctcttggt
    25681 cttgcctcat ctttctgatg aagaggaaga aagcaaggat tatctcatgc atatcgccat
    25741 tttgaatgaa gtaacgctag agttggaaaa agagttggaa gacaccagaa ataaactttc
    25801 cctctatgcg gctattgaca attatcatga acgtattgaa aatctcattt taagccaaga
    25861 aaaccaggat gatcaagaag actgggctgc tttgaaactc ttgattctta gtattgaaag
    25921 tgatggtttg gaacaggcct atgaagaggg gaatattagc aatcgtgctt accgagttta
    25981 ccaacgttat ctgaaaaata tagaacaagg aatcaatcgt aaacttgcct caagactgac
    26041 ctattatttt cttgtttcct tgaggatttt acgttttctc cttcatgaag tttttactct
    26101 tggaaagacc ttccgtagct ggaaggacaa ggagcaaagc cgtctccgtg ctcttgatta
    26161 tgaccaaatt gcagagctct atcttgccaa tacagagatg attattgaaa gtttggaaaa
    26221 cctgaaggga gtctacagac gctctttgat tagttttatg caggagtctc gtcttcgaga
    26281 aacagctatt atcagcagtg gtgcctttgt cgaacgggtt atcaatcgtg tcaaacccaa
    26341 caatatcgat gaaatgctga gaggctatta tctggagcgc aagttgattt tcgaatacga
    26401 agaaaaacga ttaattacaa ctaagtatgc caagaaatta cgacaaaatg taaataactt
    26461 agagaactat tccttgaagg aagctgccaa taccctgccg tatgatatgg tggaattggt
    26521 aagaagaaat tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttgg
    26581 attatatatg tgactgactt cgtcagtttc atctacaacc tcaaagcagg gctttgagca
    26641 acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga ttataaatga
    26701 aggagtatga catgaaaaag tggtggaaag agctgataga caagccttta ttaaaagctt
    26761 ttttgcatta ttatcaagca tcagatagtg agttgaccag tgtcgcagta gcctactatt
    26821 ggttgatttc gattttcccc ctgcttttgg tggtggtcaa tatcctcccc tattttcaga
    26881 ttcctgtggg agaatttctg tgctttatga aagacgtcct gcccccaagc ctctatgaag
    26941 gtgtggaaaa aatagccaga gaagttttga cgcaaccttc aacaggttta ttgagttttt
    27001 ctgttttatc ggcgttatgg agtttttcaa aatctatgaa tttcttgcaa aaagctttta
    27061 acaaggctta tggcgtcgaa aagagtcgtg gacttatttc ccatcagatg ctaagtctcc
    27121 tagtcagttt tggcttgcag ctcctctttg cgtttgcctt gtttttgatc ttatttggtc
    27181 agatgatttt ggctttactt gctaattatt ggacaaaaga tggcattatc tatcaggctt
    27241 tacaagggtt ggcaggtcct ctgatttacg ccctcctctt tgctatcttg gtcatgcttt
    27301 attattttct tcccaatata tctaacagga aaattagcta taccctacca ggcagtgcct
    27361 ttgttctctt agtgatttta ggtttactaa ctctgttctc tagttatctc aattactatg
    27421 tccatcattt ggtggatgtc cgaattttag gttccgttct tcttgttgtt atgatgtttt
    27481 ggtttatctt gattgctaaa attgttatcc taggcgcggt tatcaatgcc agtatgcaga
    27541 gtttgagaga tccggtcttt aaaaaagact aactatttat ccattacaaa agcgcatagt
    27601 atcaaaactt tatagaacct tgatactatg cgcttttgtg ctttgacagt tttttgtata
    27661 gtttttgtcc aagatttcta aatcatctga ttaaattcct attttcccct atcattgtcc
    27721 ctgttttttc gaaaatggaa ggagtataat aaatctatca ataaaatgat aggaggaact
    27781 ttatgggtca tattttcttt tttctaagtg tctttttggc agggattcta tccttctttt
    27841 ctccttgtat cttacctttg ttaccggtct atacaggagt gttactagat gataaggatg
    27901 gtgctcaggc ttctagcggc aaattttcaa tctcagttac tagtttatta cgaactctgg
    27961 cctttatagc aggaatttcc tttatattta ttttgttggg ctatggagct ggttttttag
    28021 gcgatttgct ttatgcttct tggttccaat atcttactgg ggcaattatt atccttcttg
    28081 gtttgcacca aatggagatt ctacacttta aggggcttta taaggaaaag aggctacaac
    28141 tgcaaggaca ggggcaaaat ggtaagggct atagtcaggc atttttattg ggcttgacct
    28201 ttagttttgc ttggacgcct tgcgtggggc cggttctggg gtctgttttg gccttggcgg
    28261 cttcaggtgg ttcaggagct tggcagggag ctggtctcat gttggtgtat acgctgggct
    28321 tggcgctacc attcttgctt ctagctctga cctctagtta tgttttgaaa catttccgaa
    28381 aacttcatcc ctatctcgga atcctcaaaa aagtgggtgg ttttctcatt attgtgatgg
    28441 gactcttggt tctgtttgga aatgcttcaa ttttaagtca attatttgaa taaaatggaa
    28501 aggaatatca atatgaaaaa atggcaaaca tgtgttcttg gagcaggttc gctcctttgt
    28561 ttgacggctt gttcaggcaa gtccgtgact agtgaacacc aaacgaaaga tgaaatgaag
    28621 acggagcaga cagctagtaa aacaagcgca gctaaaggga aagaggtggc tgattttgaa
    28681 ttgatgggag tagatggcaa gacctaccgt ttatctgatt acaagggcaa gaaagtctat
    28741 ctcaaattct gggcttcttg gtgttccatc tgtctggcta gtcttccaga tacggatgag
    28801 attgctaaag aagctggtga tgactatgtg gtcttgacag tagtgtcacc aggacataag
    28861 ggagagcaat ctgaagcgga ctttaagaat tggtataagg gattggatta taaaaatctc
    28921 ccagtcctag ttgacccatc aggcaaactt ttggaaactt atggtgtccg ttcttaccca
    28981 acccaagcct ttatagacaa agaaggcaag ctggtcaaaa cacatccagg attcatggaa
    29041 aaagatgcaa ttttgcaaac tttgaaggaa ttagcctagg aggtgtctta tgaatgataa
    29101 gttaaaaatc ttcttgttgc taggagtatt ttttctagcc ataaccggtt tctatgttct
    29161 attgatacga aatgcagggc agacagatgc ctcgcaaatt gaaaaggcgg cagttagcca
    29221 aggaggaaaa gcagtgaaaa aaacagaaat tagtaaagac gcagacttgc acgaaattta
    29281 tctagctgga ggttgtttct ggggagtgga ggaatatttc tcacgcgttc ccggggtgac
    29341 ggatgccgtt tcaggctatg caaatggtag aggagaaaca accaagtacg aattaattaa
    29401 ccaaacaggt catgcagaaa ccgtccatgt cacctatgat gccaagcaaa tttctctcaa
    29461 ggaaatcctg cttcactatt tccgcattat caatccaacc agcaaaaata aacaaggaaa
    29521 tgatgtgggg acccagtacc gtactggtgt ttattacaca gatgacaagg atttggaagt
    29581 gattaaccaa gtctttgatg aggtggctaa gaaatacgat caacctctag cagttgaaaa
    29641 ggaaaacttg aagaattttg tggtggctga ggattaccat caagactatc tcaagaaaaa
    29701 tccaaatggc tactgccata tcaatgttaa tcaggcggcc tatcctgtca ttgatgccag
    29761 caaatatcca aaaccaagtg atgaggaatt gaaaaagacc ctgtcacctg aggagtatgc
    29821 agttacccag gaaaatcaaa cagaacgagc tttctcaaac cgttactggg ataaatttga
    29881 atccggtatc tatgtggata tagcaactgg ggaacctctc ttttcatcaa aagacaaatt
    29941 tgagtctggt tgtggctggc ctagttttac ccaacccatc agtccagatg ttgtcaccta
    30001 caaggaagat aagtcctaca atatgacgcg tatggaagtg cggagccgag taggagattc
    30061 tcaccttggg catgtcttta cggatggtcc acaggacaag ggcggcttac gttactgtat
    30121 caatagcctc tctatccgct ttattcccaa agaccaaatg gaagaaaaag gctacgctta
    30181 tttactagat tatgttgatt aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc
    30241 cttaccgtat gtagggtt
//
LOCUS       DAVLIK010000023        29093 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLIK010000023 DAVLIK010000000
VERSION     DAVLIK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.023"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(437..1165)
                     /locus_tag="VXE87_001154"
     CDS             complement(437..1165)
                     /locus_tag="VXE87_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0842702.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1323..2732
                     /locus_tag="VXE87_001155"
     CDS             1323..2732
                     /locus_tag="VXE87_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0842703.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKKEYGNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKRS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2750..4045
                     /locus_tag="VXE87_001156"
     CDS             2750..4045
                     /locus_tag="VXE87_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0842704.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            4050..4358
                     /locus_tag="VXE87_001157"
     CDS             4050..4358
                     /locus_tag="VXE87_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0842705.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALEWIGEIR
                     "
     gene            4355..4663
                     /locus_tag="VXE87_001158"
     CDS             4355..4663
                     /locus_tag="VXE87_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0842706.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(5530..8181)
                     /gene="adhE"
                     /locus_tag="VXE87_001159"
                     /gene_synonym="adhC"
     CDS             complement(5530..8181)
                     /gene="adhE"
                     /locus_tag="VXE87_001159"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0842707.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(8481..8891)
                     /locus_tag="VXE87_001160"
     CDS             complement(8481..8891)
                     /locus_tag="VXE87_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842708.1"
                     /translation="MENLTNFYEKYRVYLTRPRLEILAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(8893..9321)
                     /locus_tag="VXE87_001161"
     CDS             complement(8893..9321)
                     /locus_tag="VXE87_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0842709.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            complement(9368..9667)
                     /gene="yajC"
                     /locus_tag="VXE87_001162"
     CDS             complement(9368..9667)
                     /gene="yajC"
                     /locus_tag="VXE87_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0842710.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(9784..11760)
                     /gene="tkt"
                     /locus_tag="VXE87_001163"
     CDS             complement(9784..11760)
                     /gene="tkt"
                     /locus_tag="VXE87_001163"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0842711.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            complement(11874..12965)
                     /gene="ulaG"
                     /locus_tag="VXE87_001164"
     CDS             complement(11874..12965)
                     /gene="ulaG"
                     /locus_tag="VXE87_001164"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0842712.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(13140..14750)
                     /locus_tag="VXE87_001165"
     CDS             complement(13140..14750)
                     /locus_tag="VXE87_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0842713.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKSLLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKF"
     gene            complement(14929..15633)
                     /locus_tag="VXE87_001166"
     CDS             complement(14929..15633)
                     /locus_tag="VXE87_001166"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0842714.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(15635..16498)
                     /locus_tag="VXE87_001167"
     CDS             complement(15635..16498)
                     /locus_tag="VXE87_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0842715.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            complement(16502..17167)
                     /locus_tag="VXE87_001168"
     CDS             complement(16502..17167)
                     /locus_tag="VXE87_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0842716.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRRITEAADPAGAARAFKDEIKR
                     IWG"
     gene            complement(17184..17669)
                     /locus_tag="VXE87_001169"
     CDS             complement(17184..17669)
                     /locus_tag="VXE87_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0842717.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(17749..18027)
                     /locus_tag="VXE87_001170"
     CDS             complement(17749..18027)
                     /locus_tag="VXE87_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0842718.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQAL"
     gene            complement(18050..19507)
                     /locus_tag="VXE87_001171"
     CDS             complement(18050..19507)
                     /locus_tag="VXE87_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0842719.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(19638..20261)
                     /locus_tag="VXE87_001172"
     CDS             complement(19638..20261)
                     /locus_tag="VXE87_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0842720.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKILDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(20312..21298)
                     /locus_tag="VXE87_001173"
     CDS             complement(20312..21298)
                     /locus_tag="VXE87_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0842721.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(21317..22141)
                     /locus_tag="VXE87_001174"
     CDS             complement(21317..22141)
                     /locus_tag="VXE87_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0842722.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            complement(22116..22487)
                     /gene="rnpA"
                     /locus_tag="VXE87_001175"
     CDS             complement(22116..22487)
                     /gene="rnpA"
                     /locus_tag="VXE87_001175"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0842723.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(22636..23826)
                     /locus_tag="VXE87_001176"
     CDS             complement(22636..23826)
                     /locus_tag="VXE87_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0842724.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(23877..24830)
                     /locus_tag="VXE87_001177"
     CDS             complement(23877..24830)
                     /locus_tag="VXE87_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0842725.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(24891..25483)
                     /locus_tag="VXE87_001178"
                     /pseudo
     CDS             complement(24891..25483)
                     /locus_tag="VXE87_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(25586..26032)
                     /locus_tag="VXE87_001179"
     CDS             complement(25586..26032)
                     /locus_tag="VXE87_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0842726.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFSSVK
                     IKEEKTDKKEEVVTDSSEKAEKKNQKRSLKRKRIHSQFNYNALNPE"
     gene            complement(26010..26471)
                     /locus_tag="VXE87_001180"
     CDS             complement(26010..26471)
                     /locus_tag="VXE87_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0842727.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(26434..26694)
                     /locus_tag="VXE87_001181"
     CDS             complement(26434..26694)
                     /locus_tag="VXE87_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842728.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(26699..27178)
                     /locus_tag="VXE87_001182"
     CDS             complement(26699..27178)
                     /locus_tag="VXE87_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0842729.1"
                     /translation="MDASRKNRLKPIKNTMINKILVKSLKIKAFTMLESLLVLGLVSI
                     LALGLSGSVQSTFAAVEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQK
                     LPVPKGIQAPSGQSITFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(27096..27359)
                     /locus_tag="VXE87_001183"
     CDS             complement(27096..27359)
                     /locus_tag="VXE87_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGC"
                     /protein_id="HEV0842730.1"
                     /translation="MLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAEL
                     YSLEKNEDASLRKLQDDGRITEEQAKAYKEYHDKQNTSQIVKD"
     gene            complement(27361..27618)
                     /locus_tag="VXE87_001184"
     CDS             complement(27361..27618)
                     /locus_tag="VXE87_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842731.1"
                     /translation="MKILNIKLANVEQTDLGFEHWVDVTYQVPILKNEYTVKLLLLME
                     CRIEDQEVIEYLVSTWKYRDLVLHSVRMYEIEKSESFTILD"
     gene            complement(27850..28806)
                     /gene="lytA"
                     /locus_tag="VXE87_001185"
     CDS             complement(27850..28806)
                     /gene="lytA"
                     /locus_tag="VXE87_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0842732.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLAD
                     RWKKYTDGNWYWFDNSGEMATGWKKIAEKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(28812..>29093)
                     /locus_tag="VXE87_001186"
     CDS             complement(28812..>29093)
                     /locus_tag="VXE87_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0842733.1"
                     /translation="VILAGIAVKAVKDYLVQKGGEKTIKIVEILAKNAVNAVEQVAAE
                     TGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQMNDAWKG"
BASE COUNT         8583 a         6124 c         5234 g         9152 t
ORIGIN      
        1 taaaaaataa aattttttta aatgattatg atttagaatt tatttaatat attaaaagaa
       61 gatatgaaca aataaattgg gagattgaaa ttcatttcta gcaatttgtt agaagtcaca
      121 gtctactatt ctaaccacag tatactatat gtgttacaag aaaagactca aaaacttctc
      181 gtcagtgtaa gaatgtttga aacactattt aaaactaaat aactataaga agtagatcag
      241 gtgaacaatt tcagtaccta ctctataagc tatacgaaga tatttttcaa catgatggat
      301 acaacgatca ctcttttaaa gccatcttat ttagaaaaga gaaaccattt aagcatagat
      361 gggaccttct tgccctgttt taaatttttc ttaaactaga gtctgtaaaa gattggcttc
      421 attttcacat tttctcctag gaggaatgtc gtaatgcaaa agaattaaat tcaaataaat
      481 catagcgatg acgactaatc gagtactcaa acggagttcc gttatccaaa taagccactt
      541 gttctacttc aaataccggt tccgttggaa ggagctgcaa gtaatgttgc tcattttctg
      601 aactagaaga agctcgtaag atttttgtag cactggcaat atgcaatcct aactttcctt
      661 caatgtaatt gtaaatcgat ttttgtaaaa tatcttcagt aatacctgga ataacatcgg
      721 tactcatata agtttgttcc agaacataag gtttaccgtc aataatacgc aggcggtaaa
      781 tattataaac tggactctgc aaagcgacct gtagtttttc tgctaaaaat tcatttgcaa
      841 attctaattt gaagtgaata atcctcgagt caattgtaga atgagcatct tcagatattt
      901 ttgtcagtcc ccggatatct ctttctggaa cgattaattt tctttttgag ctgccacgag
      961 agagaacaaa ggttccctgc ccacgttttc taaaaattaa gccctcagaa actaacaagt
     1021 ctaaagcttt tttgatcgtc attcgactac aggcaaactg tttagctaat gtcatttcat
     1081 caggcaattg ttcgttcatg gtatatttat tacaaagaat cttttcacga atctcattgt
     1141 aaataaataa atattttgta ctcatttaat ctggttctct ctataatatt ctaatagtag
     1201 tataacaaag ttcaagaaat gaggcaaaca caagatatgt atcaacaatt tttaaaaatg
     1261 tctagacaaa ttttaaaatt atgctatact ttatgtatag aataatagaa aggaggttga
     1321 gcatgaaaaa aaagttagta tttcctaatc tgttttggtg gggagctgct tctagcggac
     1381 ctcagacaga aggtcaatat ggaaaagtac atgaaaatgt gatggactac tggttcaaaa
     1441 cgcatccaga agattttttc gataatgtcg gacctcttgt agccagtaac ttttttcata
     1501 cttacaccga agatttccac ttgatgaagg aaattggagt taattctttc cgcacttcca
     1561 tccaatggag tcgactcatc aagaatttag agacaggtga gcctgatcca aaaggtattg
     1621 ctttctacaa tgccatcatt gaagaagcta aaaagaacca gatggatctt gtgatgaatt
     1681 tacatcattt tgatttacca gtggaacttc ttcaaaaata cggtggttgg gaaagcaaac
     1741 atgtagtgga gttattcgtg aagtttgcca agactgcttt cacatgcttt ggagataagg
     1801 ttcattactg gacaactttc aatgagccaa tggtcattcc agaagcagga tacttatatg
     1861 ctttccatta tccaaatcta aaaggaaagg gaaaagaggc cgtacaagtc atctataatc
     1921 taaaccttgc tagtgcaaaa gtgattcaac tatatcgctc attaggactt gatggaaaga
     1981 ttgggattat tttaaacttg acacctgctt atccaagaag taattctcca gaagacttag
     2041 aagcaagtcg atttacagat gacttcttta acaaagtctt cttgaatcca gctgttaaag
     2101 gaactttccc agaaagattg gtaaaacagc tagagagaga tggcgtgtta tggagtcata
     2161 ccgaaaaaga gcttcaactg atgaaatcaa atacggttga ttttcttgga gtaaactact
     2221 accatccaaa acgtgttcaa gcacaagcaa atcctgagga atatcagacg ccctggatgc
     2281 cagaccaata cttcaaagag tatgaatggc cggagcgtcg catgaatcca tatcgtggtt
     2341 gggaaatttt tccgaaagcc atttatgata ttgctatgat tgtgaagaaa gaatatggta
     2401 atattccatg gtttatcagt gaaaacggaa tgggtgttga aaacgaagca cggtttatcg
     2461 gtgaaaatgg agttatcgat gacgtgtatc gtattgaatt ttatgaagaa catttaagat
     2521 ggctacataa agccattgaa gagggaagtc actgttttgg ataccacgct tggaccgcat
     2581 ttgattgctg gtcttggaat aatgcatata agaatcgtta cggatttatc tccgttgatt
     2641 tagaaacgca aaagagaacc atcaagagat caggaagatg gtatcgcaaa gtaagtgaca
     2701 ataacggttt tgaagtagaa attgaggagt aaagagagga gatattcaga tgaaaaactc
     2761 aaaatttata gatcaatttg ccacctttgc tggtaaacta gggaaccaaa ttcatttaaa
     2821 aaccctaaga gatgcattcg taacagtaat gccattatat attttggcag gtttaatcgt
     2881 tcttttgaac aacacggtat ttaagtggat tttccaaggg gatacattaa caagattcca
     2941 atattgggga ataacaattg caaacggtac tttaagtatt tcaggtatga ttattgctgt
     3001 aatggttggt tatttcttag ctaaaaacag agatttcgaa aacccgttag cagcatcaat
     3061 gctatcatta gtttctttaa ttgtgatgat gccaaataca gtttctgtag ttcctgacgg
     3121 agcaaaagat gcggtaaaca tttcaggtgt tctttcattc aacaacacag gtacaggcgc
     3181 aatgttcgcc ggggttatcg tagcgattat tgcaacagaa ttattcattg aattatcaaa
     3241 cgttaaagct ttacaaatga accttggtga aaatattcca ccagctgtta gtagatcatt
     3301 tagcgtatta cttccagtca tgaccgtcat ctccttattt ggggttgttt cagcattatt
     3361 attcaatata actggaatga acttaatctc aatcattaca atctttattc aagaaccaat
     3421 tcgtcatatt ggtacaagct taatcggggt cattattatt tactctttag gaaatatgtt
     3481 atggctattt ggtattcacc aagcagttat ttacagtgcc atcctagaac cattactatt
     3541 aattaacatt actgaaaaca tcactgcagc aaataatgga caagccattc cacacatcat
     3601 caacttatca caaatacaaa cattcgcttt aatgggtggt agtggatcta cattatgttt
     3661 attaatagca acattcttag taagtcgcaa tgctgtttct aaaaacgtgg ctaaattatc
     3721 ttttggacct ggtatcttca atatcaatga accagtatta ttcggttacc caatcgttta
     3781 taacatttca ttagctattc catttatcac agttccagta cttggtattt taatcagcta
     3841 cttagcaaca gttacaggat tcatgagtcc tgcatttata caagttcctt ggactacacc
     3901 agtattctta aatgcatggt tagcaacagc aggggacgtg agagcagttc tagttcaatt
     3961 catcatcttt gcacttggag ttcttctata cattccattt atcaaagtta atgacaaagt
     4021 tgttgaacaa gaaatggaag gttaatatta tgaaacaaat tttattagta tgtaatgcgg
     4081 gaatgtcgac aagtatgctt gttaaaaaaa tgcaacaaag tgcgactgaa cgtgggattg
     4141 aaatttctat ccaagcaaaa tcaatgacag aagctaaaaa aaatatccat gaagcagatg
     4201 tcattctaat tgggccacaa attcgttatg agttacttgc tgtgaaagaa attgcaggaa
     4261 atatccctgt agataccatt gatatgcggg attacggaat gatgaatgga gcaaaagttc
     4321 tggaacaagc acttgaatgg ataggagaaa taagatgaca gaagaaatgg aatatatctg
     4381 ttttcagctc attgccaata gtggagcagc caaatcatcc tttattgaag ccatccaact
     4441 agctaaggca ggaaatttaa aagaagcgaa aattaaagtt gaagaagcgg aagactcctt
     4501 agtagaagcg cacaagattc actccaatct catacaaaaa gaagctactg gagaaaaaat
     4561 aggattctcc ttgctattta tgcatgcaga agaccaaatg gcttcaacag agattattca
     4621 gttgctatct aaagaattca tcgatctcta tcaaaataaa taggaacact gtcgttccca
     4681 tctgtcttta ttaatgacga ctacattgta ggaacctcca aaagttggac aaaatgattg
     4741 aaaggattgg atcctgcatt acacaagatc caatcctttt cttttactct agtttttata
     4801 atatgttgaa tctagaatag tccactgcag tttctaaaaa attgctggaa atagatgtta
     4861 agctccaatt tatttgttta tatcttattt cagtttacta tactagctta ttattctagt
     4921 gaaaaattga atgagccact atttatttaa tatgtatgat gagggaatga ctcaaaaact
     4981 tcttgtcgat ataagaatat ctgagatagt attttaaaac gaaaggacta taaaagctca
     5041 tttccttcgc acttatttta tagagatcta tcattatact ctttagaaat caaaaagcaa
     5101 cacaccttgt catcgtttta tcgtaaatct gttaatgagg gggctagtct tatctgcaat
     5161 ctcaaatcag tgttttgagc tgaatggcac tcgttttcta gtttgctctt tgattttaat
     5221 tgggccttag taaatactac tcttaaatta aactatagtg aattgaaata agatgtaaac
     5281 aactctatca ggaaagtaaa attaatttct ataaatgttt tagaagcaga tgtgtactat
     5341 tctagtttca atctgctata tattttgttt ctattctagt ttttcaaaaa gggcaaaaag
     5401 gcctcaacat cataaaaagg catcctatca ggtattcaaa aaccttgata ggatgccttt
     5461 tatcatagaa aaattactgg atctttccct caaattgagt ttttgtcttg cttctagact
     5521 gataaacaat tatttacggc gtcctggtct ttctttgtag ccatagtatg catcttcgat
     5581 gatttcttgc atatggtcta ccattggaag acgtgggtta gctggtgaac attggtcttc
     5641 ataagccagg aaggctaatt cacgagaatg ttctttccat tctttttcgt caattccttg
     5701 gtctctaaaa ttcatttgga tcccaatacg ttcaccgagt tcgtagacag cttttgcgta
     5761 agattcaacc ccttcttctg gagtagaagc tggaagtcca agcatgcgtg cgatatcttg
     5821 gtatttttca tctgcacggt agtagttgta cttaggccat gttgctgtct tagctggacg
     5881 tgtaccgttg taacggataa cgtacggaag caagatagca tttgtacgac cgtggattgt
     5941 gtggaattgc gcaccaatct tatgggccat tgagtgagaa atacctaaga aggcattggc
     6001 aaaggccata ccagcgattg ttgaagcgtt atgcattttc tcacgtgagt ggaagtctgc
     6061 attcttaact gagctttcga gattttcaaa gaccaattta atggcttgaa gtgctaaacc
     6121 atcagtgtag tcactagcca tttgtgatac atatgcttct gttgcgtgag tcaatacgtc
     6181 cataccagta tcagcagcaa caaatcctgg aactgtcaat accaaagcag gatctacgat
     6241 tgccacagtt ggtgtcaatg agtagtcagc gattgggtat ttacggttgt ttgctttatc
     6301 agagataacg gcaaatggtg ttacttcaga tcctgtacca gatgtagttg gaatcgcgat
     6361 gaatttagtc ttcttaccaa gcaatgggaa cttgaaggca cgtttacgga tatccatgaa
     6421 tttttggaca aggtcacgga agtccacttc tggttgctcg tagaagagcc acattacttt
     6481 ggcagcatcc attggagacc caccaccgag tgcgatgatg gtatctggtt tgaaggcacg
     6541 cataatctca gtaccacggt ttacagttgt gatatctgga tccggttcta catccgcaaa
     6601 gatttggtaa acaaccttat tgcgacgaag gtccagttgt tcgatgatac gatcaaggaa
     6661 accaagctct accatggcat ggtcagtaac gatcatgaca cgttcaacgt cacgacattt
     6721 ttgaaggtat tgaattgaat cacgttcaaa gtatgttttt gaaggaagtt tcatccattg
     6781 catgttattt ctccgtcttc cgactttttt gatattcaag aggttaatgg cactaacgtt
     6841 atccccaact gagttgcgtc cgtaagaacc acatccaagt gtcaatgatg gcaagaaggc
     6901 attgtaaacg tccccgatac caccaaaagt agaaggtgag ttacagataa cacgaatagc
     6961 tttaacagct ttaccaaatt ctttagtcaa ttcttcgtca gctgtgtgga tagctgctga
     7021 gtgtccaaga ccgttaaatt caaccatttg acgagcctta gtaataccat cttcacggct
     7081 ttcagatttc aaaactgcaa taactggtga caatttttca cgagtcaatg gctcattttc
     7141 gccaacttct ttacattctg cagcaagaat gtttgttcct tctggaactg taaatcctgc
     7201 ttgttctgca atccaagttg ctggtttacc aacgatgtca gcgttcaatt ttgcaccagc
     7261 acagtttttg ctgtttgctt tgacgccgaa gcagaactct tcaagaagag ctttttcttt
     7321 tttgtttaca aagtaagtgt ggtaagattt gaactctgct acaaattcat cgtaaatttc
     7381 tttatcaatg ataactgctt gttcagatgc acagaccata ccgttatcaa atgatttaga
     7441 catgacgata tcgtgtgctg cttgacgaat gtttgctgat ttttcaacat aagctggaac
     7501 gtttccggca cctaccccaa gagctggttt accacatgaa taagccgcct taaccatggc
     7561 attaccacct gttgcaagga ttgtcgcaac accttcgtgg ttcataaggg cacttgttgc
     7621 ttccatagat ggttgagtaa tccattgcac acagttttca ggagcaccag ctgcgatagc
     7681 tgcatcgcgg acgatacgag ctgcatgagc agatgattct tgtgctgatg gatggaaggc
     7741 aaagacgatt gggttacgtg tcttcaatga aatcaatgat ttgaagattg ctgttgatgt
     7801 tgggtttgtt gttggagtaa taccacaaac aacaccaact ggttcagcaa taagagtcaa
     7861 tcctgttaca tcgtcttctt cgataacgcc aactgtctta gtgtgacgca tgttgtttac
     7921 tacgtgttca caggcaaaca agttcttagt tgctttatct tcaaatacac cacgtcctgt
     7981 ttcttcaaag gcatgtaaag ccaattctcc gtgggcatcc aaagctgcta ctgatgcttt
     8041 ggcaacgatg tagtcaactt gctcttgatc caatttacgc atttcttcaa gggcaactag
     8101 agctttttga accaactcat ctacgtgttt ttcagcaacg agtttctttt cctctggtgt
     8161 cacagttttt ttatcagcca tattttcctc catagctttc aaggatcgat atcctttgtt
     8221 aattttttca caagtttatt ataacgcatt atttcaactt tgtaaacagt ttcataaaca
     8281 tttcacaaag aatttttaaa ctcttgtgaa acttttctca ttttcttttc ttatcaggtt
     8341 ttatctttga agtttgtgaa atttatttca aatatttttt atttcacaaa cttgcttgga
     8401 agagggattt ggaaagaaag ggatttacag gtaagcgctt accttgtaat tctaataata
     8461 cctcctttga taaggaggct ttatttttgt tgaaaaacgc cttgtttaaa agttccttca
     8521 taaacgactt cttgttctgt tgttagtttc ccttttcctt cagcctgacc atttacaaaa
     8581 tcaccttcgt aggtccagcc ttctttagat tgaaaggtac cttttccgtt gaaggctcca
     8641 ttgttgaagc cacctgtata ttggtctcca ttttggaagg taatggtacc ttggccattc
     8701 attttaccgc ggacaagact gccatcataa acaatcgttc cattatcgag ttttaagaca
     8761 ccttttcctg gaatatttag aaaaaagacg agtacagcac agaaaacaat ggtaactact
     8821 gccaaaatct ctaaacgtgg acgagtcaga taaacacgat acttttcgta aaaattcgta
     8881 agattttcca ccttaactct ccttttctaa acgttctaac caagcttgac agccctcttg
     8941 aacacgtcga taggtttctt caaaatctcc tgtataccaa gggtctggaa cactttcaga
     9001 tgaaaatgag taaatcttat cttgacagtc tactggacac atctgacgta agtcagaaat
     9061 atttgaagcg tccattccga taatataatc aaaggcttca aaatcttcct tactaatctg
     9121 aagcgatgtc ttgttcttgt cataaggaat ctcatactgt tgaaaaattc cctgagtccc
     9181 cttatgaatc ggattgccat gttcccaaga ggaagttgct cgactttgga tttcgtagtt
     9241 atctgtcatt gatttcataa caaactcggc catagggcta cggcaaatat ttcccagaca
     9301 gacaaagact aattttttca tcccatttcc tttcttttat agaaaaacgg gagttcgtga
     9361 tcccgtctta tttttcaatt gcgccttcta gtgaagctgt ttctttcagc ggtaatactg
     9421 tcttgatagc agctagttca aaagttaagt aaactccatc tacgtcaaga actattgttc
     9481 ccttctccgt atctacttca tcgactgttc cataaagtcc accgattgta atcacttcat
     9541 agcctttttg tagtttattt aagctttcca tacgcttttg agcttgtttc ttttgagaac
     9601 gttgcataaa gaacatcaag gccatcatac ctacaagcat gattaaaaaa gtaatatttg
     9661 gattcattgt tttctccttt gtcttttaca taggactact atatcaaatt ttagctactt
     9721 ttacaagatt gtaccttact tttctggtaa gaaaaaccag agcttacgcc ctgattttta
     9781 ggattatttc aagtttcgaa caatttttac aagattttct acagtaaagc catattctgc
     9841 caatactttt ggtgctgggg cagaggctcc gaaggtatca atacctagaa cggcaccatc
     9901 gagaccaaca tatttgtacc agttttgact tgcacccatt tcgactgcaa cacgacggcg
     9961 gactgcattt ggaagaatct cttccttgta agctgcatct tgtttatcaa agacatctgt
    10021 agatggcatg ctgactacgc ggattttttc gccttgacta gccaattctt tagcagctga
    10081 gacagcaaga ttaacctctg aacctgtcgc aatcaagatg gtatcaaagt cggctgcatt
    10141 ttcatataca acataagcac ctttagcaac cttgtcgaag tctgttccat cttcaacagt
    10201 caagttttga cgtgtcaaga caagggcagt tggtgttttc tcacttgtca ctgcaaggta
    10261 ccaagctgct tgcgtttcac gcgcatctgc tggacggaaa acatttagat ttggcatagc
    10321 acgaagacct gctaaatgct caaccggttc gtgagtcgga ccatcttccc caactgcgat
    10381 tgaatcatgg gtaaagacat aagtcacagg aagtccttgt aaggctgaca agcggacagc
    10441 tgccttcaca tagtcagaga agacgaagaa agttccaccg tatacacgaa gtccaccatg
    10501 aagggccatc ccgttcaaga ttgttcccat tgcaaattca cgaacaccaa actgaatgtt
    10561 acgattcaag cgattggtat cgtcttgaag tccatccgtc ttgatataag tcatgtttga
    10621 gtgagcaagg tcagctgatc cacctaggaa ggttggtaat ttagctgcca caacattcaa
    10681 ggcatcttga cttgaattac gagttgcttg agaaaaacca ttttctaaag ctgggaagtc
    10741 tgctggagtc acttcgactg gatcacgtcc gtcgatgatg gcttctactt ctgcagccag
    10801 ttctggatga gcttctttat aatctgcaac taatttagtc caagcttgat aagctgatgc
    10861 gccacggtct gcaacatgtt ctttgaaatc agcatatact tgttctggaa tttcaaatgg
    10921 ttcgtagtcc caaccgaggg cttgacgagt tgatgcagtt tcatctgctc caagaggggc
    10981 gccgtgtaca gcattagttc cttgtttgtt tggagaaccg tatccaataa ccgtcttcac
    11041 ttcaatcaaa gatggcttgc ctgaagcttt tgctgtttcg atagcagcat ggatggcttc
    11101 caagtctgtt ccattttcaa ccaaggcagt atgccaaccg taggcattgt aacggtcacg
    11161 aacactttct gtaaaggaat cctttgtctc accatccaag ttgatatcat ttgaatcata
    11221 aagaacaacc aacttatcaa gtttttgcaa acctgcgtat gaagctgcct cgcttgagac
    11281 accttccatc aagtctccgt ctccacagat aacgtaagta tagtggtcaa agatattgta
    11341 gccttcacgg ttatatttgg ctgccaagaa acgttctgct tgggcaaaac cagtagcagt
    11401 tgaaatccct tgccctagag gacctgtcgt agcatcaatc cctgccgtat gaccaaattc
    11461 tgggtgacct ggtgtttttg aaccccattg acggaaactc ttaatctcat ccatgctgac
    11521 atcttcaaaa ccagaaaggt gaagaagagc ataaaggagc attgaaccat gacctgctga
    11581 aagaataaag cggtcgcggt taatccagtt tggttgagct ggattgatat gaagttgttt
    11641 tgtaaagagg ctgtaagcca tcggagccgc tcccataacc acacctggat gacctgagtt
    11701 ggctttatta atggcgtcaa tacctagaaa acgaattgca ttaacagata gatttgacat
    11761 agaatttcct ttctatttga ggtgattatt gaatcacaca ttctatttta ctattatatg
    11821 aaaattatcc gtatcatgca acatacggat aacctccaaa gaatattttt atattatagc
    11881 aaagctttaa attgaatgtt agagtcttgt tcaaaacaat catcaaaacc acgtggatga
    11941 tggtattcta ctaagtgttg atcttgagga taagtgtact taccgccaac ttcccagata
    12001 aatggatgga aatcgtattg caagcgatct tttcgcattt tccaaagttc tagaatctca
    12061 ttagtagaag ccatgaagtt agaccagata tcatagtgaa ctgggataat gactttggta
    12121 cgcagatttt ctgccatacg aagaaggtcg atagatgtca ttttgtcttg gatacctacc
    12181 ggattttcac catagttatt caaagcaaca tcaattttaa agtctttacc atgttttgca
    12241 aaatagtttg agaagtgaga atctgcacca tgatagatgg ttccacctgg tgtttcaaag
    12301 atatagttaa cagccttttg agccatttct tcatctgtaa cagccaagcc agcaagttca
    12361 ccgcctgtct catcagcacc gttcactggg agagttacca agcaagtacg gtcaaatgat
    12421 tctactgcat gaatcttcat atcttttaat tcgatagtgt cacctggttt aacaacgatg
    12481 atacgttctt ttggaacccc ccatccttcc cagattcgtc cacagtggta aggaccgata
    12541 aacttaacat gctctaactt aggattgttg agaattgctg cagctgtgta tgggtcgata
    12601 tgatcactgt ggaagtgtga aactaagtaa tagtctagtt cgttgatagc aaatggatcg
    12661 ataaccattg gctgaacacg caagtttggt tgcaatttac gaacacctgc catatttgcc
    12721 atttggtgcc cacgaaccat atctttcact tttttggttg attttccacg gtttgaccaa
    12781 aggtccatga caacgttagc accagctggt gtcttaatcc aagtaccaca gttgcctagc
    12841 caccacatgg caaagttgcc ttcaggtacg acttcttctt cgatttcttc gttcaaccat
    12901 gttccccact ctgggaaagt ggctaaaatc catgactctc ttgtaatttc tttgacgttt
    12961 ggcatatgtt gcctcctttg gatataattg ttatctttga gattagtata ccacccttca
    13021 aaacactaaa aaagaccaag aaaaacacag gtttgtgttc atcattggac tgtccttcaa
    13081 atatcttcca aaaaagcttg aactactatt tcttgattta taagtgtttg aacctcttct
    13141 tagaacttac tagccaactt gctgtctaca atataagacg aaataagact agaaagattt
    13201 tcactgaaac ttttgctctt attacgaaat atattgtgtt taagatagtc tagcattttc
    13261 aaaatatctt ctgcttcaag gataggatta acccttaaaa tcggaaatct gctatccaaa
    13321 tcatcattag tagtaatcac tacatcaact tgtgcaatat cttccacact cttaaattgt
    13381 tctgttgtaa atacagtgtc aatttgctca tttggaaaat aaagtttgca ttgtttcagc
    13441 aaaagtctcg aaaccgcaac accttcatca caaacgagat aaactttttt catatttttt
    13501 tgagacgatg gtgtatactt taaaaatcct ccaatatgaa tcgtcaaata ggcaatatca
    13561 tcgtctgtta gccgaataaa ccatgctcct tctaaaattt ccgcagattt tctagtgact
    13621 aaaaataatt ctccatactt ggatcgaatt tgttttgtta gaggattttt agaaaaaata
    13681 ccgtaagtct ttctaaataa caaggattta cagtggatca tcaaatttcg taacaaatca
    13741 tccttgttct caatctccat tcggatttgt gattcaaaat accagataaa ttcttctaaa
    13801 gcaagtttta attgccgaaa atcatcactt tctgcatgaa tatccaaatc tttacgatag
    13861 gagaggagga gaacagctac aagagaaact tcaagtcctg acaaagaaat ttcaaacttt
    13921 tgaaacaacc gttctcctaa tttcttagac acctgatact ctattctttt tcttatcaaa
    13981 gaaaattctt tctctatatc ctgatgtctt tcttgatact gttcaacatt atgacagctt
    14041 aacagcaaat aaggtagaac ctgcaacata aaagttattt catgatggtt tattttcttc
    14101 cctaaatctt gttcaactaa aggaacctgt tccttaaaaa attggttcat ttcaacagaa
    14161 agcaaacact catcatctaa cctctctttc atcttatctt ctaaaataga tacaaaagtg
    14221 gcattttctt ccataaaaat atgatataga agcgattgaa gatactgaat tttattaaga
    14281 gggtgggcat gaaggtggta tccctgtgac ttgctcactt gcaagatcac ctgatattgt
    14341 tccaaagtta gttgataacg aatactattc aaatcattga gaacagtatt cctagatacc
    14401 tctgttaact ctatcaattt ttcaatcgta atacgttctt tagaaatacc tatccatagt
    14461 aacattatca tcatacgttc atgcgcactc atgatataat cgtacgaatc tacttccgat
    14521 aatagtttac aacaagcatc tctctgctct tccgttaagt gaataccaat tcgtggaata
    14581 ctaatgatgt gaagcgcctc gtcacccaga gcagcattga ttttgtcaat gtgataataa
    14641 attttccttc ttgactcttt caaatctttc gaaatcgcca taatcgtttt ggacgtttct
    14701 tgatccatca aatattgaag caaatcacaa cttgccttat ccagtaccat attaaaaaat
    14761 cccccaaatc tattgatatc acagcaattc tttttatttt accatatata tatcaagcgc
    14821 tatttctaaa aaatctttta aaattacttc aattccaact ttactctcaa taaaaatcaa
    14881 atgtaaaaag aggagctaaa tttatctttt tctcctcctt catcgttctt acttttgacc
    14941 ataataagca tttggtccat gtttacgttg gtagtgtttt tctagtatgt actggggagc
    15001 aggtccaact cttggattga tttgttctgt aaagcgattc atctttgata cttcctctag
    15061 tacgacagag tgataaacag cattctctgg atttttgccc caggtgaatg gaccgtgatt
    15121 gcgtacaaca attcctggta cttcaaccgg gttaagtccg cgatgttcaa actcttctac
    15181 gataaccagg ccagtatctt tttcataggc cacttctact tcgtccttgg tcaaactacg
    15241 ggcgcaaggg attgaaccgt agaaataatc tgcatgggtt gttccgtaga aaggaatatc
    15301 acgacctgcc tgagcccaag caacagcttc tgtcgaatgg gtgtgaacca cactaccaat
    15361 ttctgaccaa gccttatata attgcacatg agttgggagg tcggaagatg gtcttaaatc
    15421 cccttctagg atcttaccat ctagatcagt cactaccatg ttttcaggtg tcaattcgtc
    15481 ataatccacg cctgatggtt tgataacaat gacaccgagt tcgcgattaa cttcagatac
    15541 attcccccag gtaaatttga caagtccatg ttttggcaat gattgattgg catcacagac
    15601 tcgtttacgc atagcattga ttacttgatt catcttacat caaacctgct ttcttaatga
    15661 gtggatagag aaaagcttgc gcctcttgaa cggctgcgcg tgtttcttct actgtttcac
    15721 aattttcaga ccacatttcg attaggaaag gtccattata attggtttcc tttaaaatat
    15781 cgaaagcttc ttcccatttg acacaacctt gcccgaaagg tacatctcgg aactggccct
    15841 ttgaactttc tgtcactgca taagtatcct tgagatggag agctgcgatg gcatgatgac
    15901 caagataaaa ctcactatag atatcattat gccatgcaga cacattacca atatctggat
    15961 atacaaagag gaagggagag tcaatctctt tttctatagc caaatatttt tcgatgctat
    16021 tgatgaaagg atcatccata atttcaatag caagtaccac ctgagcttct tcagcccagt
    16081 cacaggcttt tctcaaattt ttgataaaac gttggcgtgt ctggggtgac ttttcctcat
    16141 agtaaacatc gtaaccagct aattgaatcg tacgaactcc caagtcttga gctaattcga
    16201 tacatttttt catgagttct agagattttt cctctagaac tggatctttt gaacccaatg
    16261 ggtagcgacg atggcctgaa aaacagatag aaggaatacg aacaccagtt tcatagattg
    16321 ctttgacaac ttccaagcgt tcttccttac tccagtcaag tcttgctaaa cgctcgtcac
    16381 gttcgtcaat agacatctcg acaaaatcaa agcctaactc cttggcaaaa tttaaacgtt
    16441 ctagccaagt aaagtgtgtt ggggttgcct tttcataaat tccaattgga cgtaccatga
    16501 tttaccccca aattcgtttg atttcatcct tgaaggcacg cgctgctcct gctggatccg
    16561 cagcctctgt aattctacga cctgcgataa aggtaaagac atcaacacct tcaaagagtt
    16621 tgagagtatc tacatctaga ccacctgtta cagatacacg gaagcccatg tcaatgagtt
    16681 ttttaacctt attaaggtct ttttcacccc aagtttcacc agcaagaaga gcatcacgag
    16741 attggtgata aatagcttgt gagatacctg catctagcca aagctgagct tgttcaaaag
    16801 tccaatcgcc ataaagctcg atctggattt cgcctcgttc tcctcgttca gtcttgatag
    16861 cctttagagc tgcttccata gtagggatgg ttgcacaaca gatacaagtc atccagtctg
    16921 ctccacgaac cgcattattt ttagcaactg ttccaccagc atcagcacat tttgtgtctg
    16981 ccacaataat cttatctggg aaaaggctac gcaagacttc agccagttca cttccaactt
    17041 gaagcaagca aacagttcca gcttcgataa tatctacttc ctgaccaaca gaaacagctg
    17101 ctttaatcgc tccttgcaag tctgaatggt ctaatgcaac ttgtaaatta ggtattcttt
    17161 ttgtcatttc tttattcctc tttctaactt tccaaatcca atccttcgag ataagggcta
    17221 tccttagatt cttcaatcat agccaagaca tcttctttag tctggcaagc ctgtaaacgt
    17281 gcaatagaat cttctaattc aaacagggca ataatttgtg gaatggccac acttgtgtga
    17341 atttttgaac ttgttgctgc tagtgccaac aaaacagata cctctttccc atctgaaaat
    17401 acaacaggat tttgtaaggt aatcaatgaa aaggcatcac tttgcacacc agcttcaggt
    17461 ctagcgtggg gcatagccat acctggcatc aagatatagt aaggcccata ctcttcagtc
    17521 gattcaatga tagcatcgta atactctggc aaaattgccc cactttcaat caagggatct
    17581 actgctacct tgactgcttc tttccaatcg ttagcctcta aacctagtcg gatcgagtcg
    17641 ttgtcaatta aagcttgttt taaattcata tctgcctcct ttatttaaag agggagaagg
    17701 acagaaacga taactctcag tttctgtcca gtcccctcca accttttact atagtgcttg
    17761 actgagtttt tcggtgattt ctttatcatc catcaagtta tcaagaccaa ttaacttccc
    17821 attagttcgc ccttccaatt cttgaatcaa atgaagagaa gcgattacga tgtcatatcc
    17881 tactgctaaa cctttagctt caccgacact gcatgaattg actgtaaaat ctgtttgatt
    17941 aagcttacgg agagcatttt caaccttcat cttgataacc attgatgaac ccattccatt
    18001 tccgcacgct gctaatactt taaccatttt atttctcctt ttctagatac taagcttctt
    18061 cttgaacttc accgttgtaa tatttctctt tatcttttgc tttggcaaat tgaagttgag
    18121 gaataacaag caagaagaga cacacaagta cataaccaac aataccaagg tatttgaaga
    18181 tatatccaaa tccaagccat gggaattcaa agtcgatatt tccatggtag ccaccataag
    18241 atgccaaatc gagaagggcc acacaaagag ctcctagagc aacttgaagg acacctgata
    18301 taaaggaaag gataacagcc gctttccatc cgccgcgttt atcagcgtag accgcaatgg
    18361 ctgcattgtc aaagaacact ggtacaaatc ctgtaataat aagaatcgga tttttaaaga
    18421 cgatgagcaa gacaattgta atcaattgac caatcaaacc aaaggtaaat cctgacaaga
    18481 cagcatttgg agaaccaaat ccataagaag ctgcaacgtc aaccgctggg aatgaacctg
    18541 gcaacaattt gtttgaaata ccttggaaag cgtttgttaa ctcagatacg aacattcgga
    18601 caccttgcat caaaacgaac aagtaaactg agaaggtaaa ggctgtttgg ataatgtaca
    18661 taaagaaatc ttgtttagca ggattgaata gagttcctga agtgatgact tctttattag
    18721 acataatgtc tggacccaag attaaaagaa tggccccgaa gaatacgagc atcaaggtag
    18781 cagatgcaac aactgtatcg tggaagattg agaggaactt aggtaattta agattgtcta
    18841 aactttcttc tttcttacca aagcgtcctg ctactttatc tacaaaccag attgcaaatt
    18901 gctgttggtg accaatcgca aatccgccac caccagtcaa gcgttgagtt gcctcaacag
    18961 tcatatttga actaactgcc cagtaaagtc cacagatgat accaatcgct gctgtaccgt
    19021 aagcattgcg caattgtggt actaagaata gaaccataag agatactgtt gcagcttgtt
    19081 gtaccatgat gtgaccagta ataaagaggg ttcttacctt cgtaatcttt cgaagagcta
    19141 cgagcaagat atttattccg aaaccaatca atagagctgt agttgcagtt ccaacaaaat
    19201 ctggaaactc tgctgcaatt ttgttgtttg ctgcagcaag tccaaagtaa gggtcgataa
    19261 ccgctgcacc aatttggaat ttgtagttaa gagctgctaa gattggacga aaggttgtaa
    19321 ccaaaccacc agcacccacg ttaagcaaca tataccctac tgttgcttta acaaaccctg
    19381 aaaaaacgtc atgggcaggt tttttcaaaa gtgcatatcc tatcaacacc aataaaccta
    19441 cgaaaaatgc gggattctgc aaaatattgc tagaaaacca atttagaaca cttgaaacga
    19501 cttccataat tgttctcctt ttgaattgtt tttgtaagtt tattatataa tgcgaaagcg
    19561 caaacaaaaa gaccaagaat tacacagcgg actgttcact cttggactgt atgatttatg
    19621 atgttttaca aattatctta ttttctcgta gctagataat agggaagaat tttagaataa
    19681 gacttcaata agccttctac gatttcttct tcagacgaat tttctgtcat aggaacatct
    19741 accttcacta aaacttttcg aacttcttga cttctcacct tctcgcgtaa agtacgacgc
    19801 ttttcttcat tcgcctccca ccgttgactt tgaccattag agtaggttag ataataaatc
    19861 cctttaacgg ttggaatgtc taaaatcttg gcctgcttgc ccagtgtttg ctcatccttc
    19921 ttacgttcga tgaaactgac ttccaaagaa attccaaagt cagtagatgt cccatacaaa
    19981 cgtaaggcca tcataggttc tgtcacttgt ccgtctctct gtagataaac ccaaaaatgt
    20041 ggtctcaaac gctgggcctg attcatccac tgactagtct gttggagttg ccattctgga
    20101 tggcttgctt gaaaggcttt ggccagttct gtaaaagcct ttcgggcctc ttgtcctttg
    20161 tggcggaacg ccagcatctt ctctcgctct gctcccgctt tatcaggact acggtactgc
    20221 aaaccagaaa agtctagata gtctcttatc ttattcaaca tcagtttaac ctcctctagc
    20281 tagcaaaaaa tcaggtcaac cctgatttta cttattctgt atctacaacg acatagcgat
    20341 ttggctcatc accttcagag taactggtca cgccatccat acgtgaaata atacggtgga
    20401 taatcttgcg ttcactattc gacattggat ctgtttgatg actacgtcct tcttctaaaa
    20461 cacgaatcgc caatttttgc gcataggtct gcaagacttc tgcacggtgt tcaacataat
    20521 cattgacatt aatagtgata tagaaggttc ttgaatagca gttgtaaaga taattttgag
    20581 ccaacagttg caaggccttc aagactttac catggtagcc gataatacga cctggttcgt
    20641 tagtatcaat ttgcaaattg atgctacgac ggttataatc atttgaaagt gtagcctcaa
    20701 catccatgtc atcaataatc gtttgaacat aagcagtcac atccgtagcc acctgggcaa
    20761 tatcataact ttgctcgacc ttcaagccca tctctttcaa gtcttgattt tcagtttgat
    20821 cttgctcagt ttcaaggtca tcagcgcctg cttcttccct catcgcttcc tcgatttgaa
    20881 gttcatttaa aatctcaatg tgaccagttt cttctaagat agtgctggca tgtctttcat
    20941 gttttaagat ttcagccttg acttcatcag aaataccttg accttcttcc tctatttttt
    21001 taatagcatc aaccacatga ccaaggtcaa cggtttcttc actaacagtc ttcacaggct
    21061 cgttcaaatc attgattttt ttcggaacgc cttttactac ctgttgattt gctttgacaa
    21121 cagtcgtttc actaatcgct tcaatatcca cttgggctgg ttttttacca aatagaccaa
    21181 gaaagccttt tttctcccta gaaatgactt tgatatgagc cttcattctt ggaatatcta
    21241 attctttcaa tcctttctgg attgcttctt caacagttga acctgtaaat actaccatta
    21301 ccagattcct ccttatttat ttcgttttct gagccttttt cttggctttt ctttttctat
    21361 tttccaaatc tttttgtgcc tgtactacgg cctcgcgctc tgcgataatc ttgaatggat
    21421 tattcaagaa ataggtttgc aagacttgat aagcattaga cactgtccag tatagggcga
    21481 ctccacctgg cgcataaact gcaaagataa aaatcaagac tggaatccca tacatcatcg
    21541 cagtcgtagc gccatttcgc tcagacaaag ctttgttgga caaccaagta cttaaaaagg
    21601 tgaatactgc tgctaaaatc ggaagaacaa gggttgtatc cacactacca aggttaatcc
    21661 ataagaaatg acctgtcttt aaaaagtcaa ctcttgatag ggcttggaac agggccaaaa
    21721 taaccggcat ctgaatcaaa atcggccaaa gagagtctga ctgtctgaca cccatttctt
    21781 taaatacttt acgcatttcc tgctctagtt tggttctgct ttccatatct cgacctggat
    21841 attgttctcg aagcgcctta atgcgtggct gagcttcctg cattttccta gaagccacca
    21901 tttgcacctg aaagactggc aagaggactg tacgaatcaa gaccgtaaag agaataatcc
    21961 ccactccgat actaatatca aacgataaaa agcgaatgat ttccgcaaag aagtaaacca
    22021 atttactcca aaaatcagcc gattcggctg taatatcgct agttacccca ttagtcgcac
    22081 aggctgtcat gattaacaga gacagtccta gcaaactagt caactttagt ttctttttca
    22141 ctcccatttc cttcccggta aatctttgat aattttaata catggagtag atttttctcc
    22201 atctctgcgt atcccaaggt ttcgactcct tttcgagcaa tgacaacaaa gtcgacatct
    22261 tctaccagac tcccttttgc attctggata atatgccgaa tccgtcgctt aatttgattt
    22321 ctagtgacgg cattccccag ttttttgcta actgatagac ctactcgaaa atggtttttc
    22381 tggttttcta attggtagac cacaaatttg cgattagcaa aacttgtccc ctccttgaaa
    22441 atcgccttaa aatctttctc tctttttaca cgaaagtttt tcttcaaaac tcaactccat
    22501 ctattaaatt actactatta taccatattt ttcaaaaaag ccaatcatag caaggttttg
    22561 gacaatttca tcagaaaaag aagctggaaa aataactttc ccaactcctt gtattgaata
    22621 tttttttagt ttcacttatt ttttcaagcg ttcaacgtca cgggcaatga ctaattcttc
    22681 atctgttgga ataaccaaga cacggatttt agctgcctct gttgagatgt ctcctgtaac
    22741 gccaaagaca ttcttttcat catcaacatc acaaccaaac cacgaaatcc ctgagattac
    22801 atcacgacgg aaattctctg cattttcacc gacacctgct gtgaaaacaa tggcatctgc
    22861 tccatttagc actgcaaggt actgaccgat atgtttttgg atacggtcaa catacatttc
    22921 ataagccaag ctagcctcgt gattcccttc tgctacagct gcttctatat cgcgcatatc
    22981 gctagaatta gcagaaactc ccaaaagacc tgattcacgg ttaagaacac gactgatatc
    23041 ttctggtgtg ttaaaatcct ctgtatattg cattaaataa ggaatgatag ctggatcaat
    23101 atcccctgta cgcgttccca tcataatacc accaagagga gtgaacccca tagaagtgtc
    23161 tacagatttg ccggctttca cagctgtaat tgagcctccg ttaccaatat gacaggtaat
    23221 taacttcaag tcttctaatg gacgtcccaa gagttttgca gcttctcctg ctacaaactg
    23281 gtgacttgta ccatgagcac cgtatttacg aaccttgttt tctgtgtaat attttgttgg
    23341 tagagggtag cgataagctt tctctggcat acttgtgtgg aaggaagtat caaaaacaac
    23401 tacactggta atgtctggca acaattcctt gaaggcacga acacctgctg cattggccgg
    23461 gttgtgtaga ggagccaaca aactcaactc ttcaactttt tctaaaacat ctccctcaac
    23521 aactgttgat tctttgaaat attctccacc agcaacaaca cgatgtccaa cacctgtaat
    23581 ctcgtcataa gccttgataa tatcgaaacg aatcaagtca tccaataaaa ttttaacggc
    23641 ttgtgtatga ttttcaatat ccaaaatttg ttgttcagaa cggccgtcaa attttacagt
    23701 tgaaattgaa tctttcaaac cgatacgttc aatcaaacct ttcgccaata ctttttcttc
    23761 tggcattaag tataattgcc atttcaaact tgaacttcct gcattgattg caattgtttt
    23821 tgtcataaca tgatacccct ttttaagcgt tttcaactat tataacaaaa tctattttat
    23881 atttcagtac cttgagtcca tttttgaaaa ttttctttaa atttcattaa aacacttgca
    23941 tcttgcaagc tagcaagtgg ataaacaaaa ggctctactg ctatttcatt tttcttctgt
    24001 aggataaaaa tagtcttaga ttgtttagca ttagcaaaga gattttcagg cagactaatc
    24061 atagcaacca gactcgcctc ttctttcagc cattctttta acaaatcact ttgaggactg
    24121 gtcaacaaat cactcggagc tagaaaaata gcgtatccgt ctgacttgag gtacttaagc
    24181 ccttgttcca tgagcaagtg atgggcgtaa gtatgttctt ggctagaagc aacttgatgg
    24241 cgcgacgcaa cggcatcatc aggataatag ccaacaggca agtcactgat gaccacatcg
    24301 ctttctttga gcatttgtgg acgaacggca tctccttgga caaagccagc ctgcaaacca
    24361 attacatctg ccatgctagc tgccagatca atcagtaaat catccacttc cattcccaag
    24421 taatccacct ttttatcaag cgaggtcaag aaagtagcgc ctagaattcc catcccagaa
    24481 cccatttcga ggatagtaat ttcctcctct ttaaacaact cttccacaat aaacaccaaa
    24541 agcaaagcaa tagcatccgg tgtaaactgg tgattggcct gcaagggttc tgtttgccca
    24601 gccttcatca agagaaactg gtaggtcttg agccattctt ctttgcgtag tgctaaacgc
    24661 ttaagggcct gattgttgtc tttgacctgg tttagctcag tttcaccatc cagatagatg
    24721 ctgttttgct ccaccaaggc gtcataaaag ttggtcgcca aatcactttg gatgacttgg
    24781 acattctcta gtaaataggt ataagcttgt tcaatttttt caaaatccat attcctatct
    24841 tatcaaattt cccttctttt ttccatcctt atagaaaaat cactccctga ctaggcgagt
    24901 gatttttggg ctactattaa aaagaattct gagtgatttc cttgaaacag gtcttcagcg
    24961 ctatagagaa tctgactatg cacagatgaa aaaccatgct caattagctt gttttccagt
    25021 tcagctaaat caaatccatg atgattagct tctgtcttgg taaaatcagc aatgatgagt
    25081 ttcccatctt ccttcaaatg ttgatgaaac agtgagagag ccgcatccaa atcaggcata
    25141 tgatgaagaa cccgactaac agcaaggcaa tcaaactctt tctccaaggg atttttcggt
    25201 aaatcttgct ccaaaaactg gatattcttg attgcttgct gctccacttt caaacgagct
    25261 tgctccaaca ttttctcaga aatgtctaca agagtgactg acttagcctg cttggctagg
    25321 ggttaggggc aaggctaata gacccgccac caccgaaatc taaaatttct ttgtctgata
    25381 gaagatcaat ctgtttctcg gctgcttgac ataccaagtt tgcgaggaag atatttttag
    25441 gggaatcgaa agtttctgct ttgtggttaa aatcatgttt catatcttta gtttagcaca
    25501 aagtatagta aactgaaata agatataaac aaatgaattg gagattaaca tccatttcca
    25561 gcaattttct agaaactaca gtggactatt ctggattcaa cgcattatag ttgaattgac
    25621 tatgaattct ctttcttttc aggcttctct tctgattttt tttctccgct ttttcgcttg
    25681 aatcagtcac tacctcttcc tttttatccg ttttctcttc tttgattttg actgaagaaa
    25741 acagaaactc atattgactc ttatccgtac gaaccctcgt cactaagcca gttttcttgt
    25801 tttgatagct tacctgacct agattaaaaa cctgttcccc actttcttgc tcaaccttat
    25861 ctttggttcg tttagccata gcaaaagcaa ccaatttttc tttattcaaa gcatagtctt
    25921 gatagtgggc gacttgtcgg ttcaagtaaa attgcaacaa aagactaaag atagctgcca
    25981 tggtgactgc atagaggaga acacctgcct taactttctt ctttttccac acgatagatg
    26041 aactcccttt ctaagccttt ttgaaactgg aaacgaaaat gaaccagttg attgtcctct
    26101 gtaatctgag ctgatttgag gccataaacc ataggctgat acccccgtcc actagcatcg
    26161 gttttacgaa aatcgtctga ctttgactta ccgatggcga tgtccttgcc atcttgcttc
    26221 atgtataggc gattgccttc tactttttcg aactgcgaac ggtctaattc tacctcaagt
    26281 tggtccacaa acaagagcca ctccttttgc tcgctttgtt gctggtagcg aacttctgaa
    26341 atgaggagct gactcatagc ttgaaaaagg agtaatcccc cactgatgac aatgagggca
    26401 agcagggatt ctaacaaggt aaaagccttg accttatggc tctttgattg ccaacaactg
    26461 ttctgaacca tggtagacct ccaatccttt ttcactagaa aatacctgaa tctcaactcc
    26521 gttgatgctt acctgatttt gccccgtctg caaggccatc ttagctaccc tcaagacttc
    26581 ttccttttgc aagatttttg cttcctcttg cctatttttt tgaatttgtc ccaaaaggag
    26641 ggtcgcaatg ctggcaaaga tagctagagc gactactgct tccagtaaaa tcactgccct
    26701 aattttttgt ttccttaatg cgtttaattt ttccatttcc tagatataat tgatagcgaa
    26761 tcgctccttt actggtctga aattcaacct tagccaggga cgaattgccc ccagcacggt
    26821 caaatgtaat actttggcct gatggggcct gaattccttt agggactggc aacttttgac
    26881 tgccattgct aatcatctgc ccatccaagt tcagactagt cttttgttga ctagctacac
    26941 tgcgtttttg ggtttcccga tagagttctt caaactccat aaagaaaatc tgttcctcta
    27001 ccgctgcaaa agtggactgg acagagccgg acaagcccaa ggcaaggata ctcacaagtc
    27061 ccaaaaccaa gagactttcc agcatggtaa aggccttaat ctttaacgat ttgactagta
    27121 ttttgtttat catggtattc tttataggct ttagcctgtt cttccgtgat gcgtccatcg
    27181 tcttgtaact ttcttaggct agcatcttca ttcttttcca agctataaag ttctgcctgg
    27241 ctttccacca ccttaacaac agctgctttt cctttgtcat tgactgcttc tttttgcttg
    27301 gtcagattag gtacaaagag caagaaaagc acgctgataa tcagcaagac caccaacatt
    27361 tcaatcaagg atagtaaaac tctcactctt ttctatctca tacatcctta ccgaatgcaa
    27421 cacgagatca cgatacttcc aagtgctgac cagatactca ataacctctt ggtcctctat
    27481 cctgcattcc ataagtaata atagtttgac cgtgtattca ttcttcaaaa tcggaacctg
    27541 ataagtcaca tctacccaat gctcaaaacc taagtctgtc tgctctacat ttgctagttt
    27601 aatatttaaa atcttcattt ttattcctcc tacttatcta ttcgtaaaag aagataaaaa
    27661 gttatgaaaa aatcattact tttttaattc agacagtact ttcagagcaa ttttgttaat
    27721 gtcaacaaaa ttggcaacca agcgatttaa tactatttgt tgacgccaac aagtcaattt
    27781 tcagacaaac aaaaaaaccg caagcctgag cctgcggtga aagaacaatt tagaaagttt
    27841 cctttctatt tatttaactg taatcaagcc atctggctct actgtgaagt ctggcttatc
    27901 tgccagtgtt ccgtctggtt tgaggtagta ccagcctgtt ccgtctgcgg actggataaa
    27961 ggcatttgat accatagcgc cttctttagc gtctaagtag taccaagtgt ccttgtactt
    28021 gacccagcct gtcttcatgg caccttcttc gttgaaatag taccacttct cagcaatttt
    28081 cttccagcct gtagccattt cgcctgagtt gtcaaaccag taccagttgc cgtctgtgta
    28141 cttcttccag cggtctgcaa gcatatagcc tgagccatcg aaataatacc aggtaccgtt
    28201 gattttctca aacttatctt ttggataaga gccgtctgaa tgtacgtacc agtagccagt
    28261 gtcattcttc tgccagcctg tttcaatcgt caagccgttc tcaatatcat gcttaaactg
    28321 ctcacggcta atgccccaac ttgcaagata tggatatgga tccacatggt ctgagtggtt
    28381 gtttggttgg ttattcgtgc aatactcgtg cgttttaatt ccagctaaac tccctgtatc
    28441 aagcgttttc ggcaaacctg cttcatctgc tagattgcgt aagagttcga tataaaggcg
    28501 gtagtccgtc atgaactctt ctttagttga atggctttca atcagttcaa ccgctgcgta
    28561 actctcagta ttccaaccgc ccccaacatc ccaacttccg ttgttcacag gacctacttg
    28621 catgacacgg ccatttccga caacatgtga aaagaaccct agttcagggt cctttctata
    28681 gtggtaatca gcctcatttt gagctgttga gttacggttg cctgttgagt gggcgtgtac
    28741 ttgtcgataa ggctgcacac cgacctgagg caagcctgta cgtagtctgc ttgtatcgat
    28801 atccattact cttatccttt ccaagcgtcg ttcatctgtt tcactgcgga ctctacgaag
    28861 gtgtctaagt ctttgtcagt catgctaata ttgtattttg taagctcagc acggacttta
    28921 gcgcgagcct gtgccagttt ttcatctccc ttgtagccag tttcagcagc tacttgctca
    28981 acggcattaa ctgcgttctt agccaagatt tcaacaatct tgatagtctt ttctccacct
    29041 ttttgaacca ggtagtcctt gactgccttg actgcgatac cagccaaaat aac
//
LOCUS       DAVLIK010000024        28195 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLIK010000024 DAVLIK010000000
VERSION     DAVLIK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28195
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.024"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            27..380
                     /locus_tag="VXE87_001187"
     CDS             27..380
                     /locus_tag="VXE87_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842734.1"
                     /translation="MFSTLEKIKELAKKRGIPLTKLEESLGYSTNYFYTLKTKTPNSE
                     RLQQIADYFNVSTDYLLGRTDNPAIAGDDTISGYTSDDLRKMAENAKTFDGKPLTEED
                     IDAIQNIIEIYLRGR"
     gene            382..1476
                     /locus_tag="VXE87_001188"
     CDS             382..1476
                     /locus_tag="VXE87_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842735.1"
                     /translation="MTITEQDALLFNTLFENIYHQLPSVDSSKDYWFVRAQKGQFYKS
                     FQTGGYIAIGWNYITLDDLKNLDEDAIKGKIKEFDSRIEKPGSAYNQMMKFAYSLKIG
                     DIVIVPSESPNDFLVGEITSRPYTESESNIESASNVCPFNKRMNVHWFGVIPNRDIDP
                     KLYKLVYSGHTITDANAYKKFINRGLYDAYIDHDHMSITFKVQEENNIDAFEYSTFLH
                     TVLQMVNVVKESDELKDEKVVLRTNVQSKGPIELLGHPEILIPVLVFIIILTGGIAFR
                     NLIKRNGANFEVDSKLGKFKAQLNSDGDEAIKKAQANKINAEAIALLIDKGMSPQFKG
                     ATSQLDIKAPEVATRILQDELLESPEKVEE"
     gene            1699..2079
                     /locus_tag="VXE87_001189"
     CDS             1699..2079
                     /locus_tag="VXE87_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0842736.1"
                     /translation="MTIEELVDSHGVTLAYFDNELWQRPGVYIKEISIIFINRELSED
                     AKKRVIYHELGHLEHSTALYQNNHTRCENEANRHMIHKLLEEELALSDDHQSFNYIQF
                     MQKHKLRTVTDELMVIDEYYELIG"
     gene            2221..3348
                     /locus_tag="VXE87_001190"
     CDS             2221..3348
                     /locus_tag="VXE87_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0842737.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(3436..4347)
                     /gene="whiA"
                     /locus_tag="VXE87_001191"
     CDS             complement(3436..4347)
                     /gene="whiA"
                     /locus_tag="VXE87_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0842738.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(4344..5321)
                     /locus_tag="VXE87_001192"
     CDS             complement(4344..5321)
                     /locus_tag="VXE87_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0842739.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(5318..6208)
                     /gene="rapZ"
                     /locus_tag="VXE87_001193"
     CDS             complement(5318..6208)
                     /gene="rapZ"
                     /locus_tag="VXE87_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0842740.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(6260..6640)
                     /locus_tag="VXE87_001194"
     CDS             complement(6260..6640)
                     /locus_tag="VXE87_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0842741.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(6651..7238)
                     /locus_tag="VXE87_001195"
     CDS             complement(6651..7238)
                     /locus_tag="VXE87_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0842742.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(7247..8479)
                     /gene="clpX"
                     /locus_tag="VXE87_001196"
     CDS             complement(7247..8479)
                     /gene="clpX"
                     /locus_tag="VXE87_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0842743.1"
                     /translation="MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQE
                     IIREELAEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(8516..8686)
                     /locus_tag="VXE87_001197"
     CDS             complement(8516..8686)
                     /locus_tag="VXE87_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842744.1"
                     /translation="MERSIFGFFTAMLCLVCLLAGAQAFRKKRYGLSVLLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(8686..9192)
                     /locus_tag="VXE87_001198"
     CDS             complement(8686..9192)
                     /locus_tag="VXE87_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0842745.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWYLPAELQHFKETTLNHAIL
                     MGRVTFDGIGRRLLPQRETLILTRNSEEKIDGVTTFQDVQSVLDWYQAQEKNLYILGG
                     KQIFQAFEPYLDEVIVTQIHARVEGDTYFPEEFDLSLFETVSSKSYTKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(9322..9840)
                     /locus_tag="VXE87_001199"
     CDS             complement(9322..9840)
                     /locus_tag="VXE87_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0842746.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMRGRGFMVWHPKMDEYMDALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLIALFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            complement(10339..11844)
                     /gene="lytC"
                     /locus_tag="VXE87_001200"
     CDS             complement(10339..11844)
                     /gene="lytC"
                     /locus_tag="VXE87_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV0842747.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELKRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            complement(11882..12640)
                     /locus_tag="VXE87_001201"
     CDS             complement(11882..12640)
                     /locus_tag="VXE87_001201"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0842748.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(12738..13415)
                     /locus_tag="VXE87_001202"
     CDS             complement(12738..13415)
                     /locus_tag="VXE87_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0842749.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            complement(13424..14368)
                     /locus_tag="VXE87_001203"
     CDS             complement(13424..14368)
                     /locus_tag="VXE87_001203"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0842750.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            complement(14550..15062)
                     /locus_tag="VXE87_001204"
     CDS             complement(14550..15062)
                     /locus_tag="VXE87_001204"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0842751.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(15149..15907)
                     /locus_tag="VXE87_001205"
     CDS             complement(15149..15907)
                     /locus_tag="VXE87_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0842752.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            16115..16261
                     /locus_tag="VXE87_001206"
     CDS             16115..16261
                     /locus_tag="VXE87_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842753.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            complement(16408..17538)
                     /gene="ugpC"
                     /locus_tag="VXE87_001207"
     CDS             complement(16408..17538)
                     /gene="ugpC"
                     /locus_tag="VXE87_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0842754.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(17821..17906)
                     /locus_tag="VXE87_001208"
     tRNA            complement(17821..17906)
                     /locus_tag="VXE87_001208"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17870..17872),aa:Leu,seq:aag)
     gene            complement(17988..18563)
                     /locus_tag="VXE87_001209"
     CDS             complement(17988..18563)
                     /locus_tag="VXE87_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0842755.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            complement(18563..19351)
                     /gene="codY"
                     /locus_tag="VXE87_001210"
     CDS             complement(18563..19351)
                     /gene="codY"
                     /locus_tag="VXE87_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0842756.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            complement(19615..21189)
                     /locus_tag="VXE87_001211"
     CDS             complement(19615..21189)
                     /locus_tag="VXE87_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0842757.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            complement(21388..22614)
                     /locus_tag="VXE87_001212"
     CDS             complement(21388..22614)
                     /locus_tag="VXE87_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0842758.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKALT"
     gene            22807..24123
                     /locus_tag="VXE87_001213"
     CDS             22807..24123
                     /locus_tag="VXE87_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0842759.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVTAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            24222..25565
                     /locus_tag="VXE87_001214"
     CDS             24222..25565
                     /locus_tag="VXE87_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0842760.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            25565..26347
                     /locus_tag="VXE87_001215"
     CDS             25565..26347
                     /locus_tag="VXE87_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0842761.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            26473..27555
                     /locus_tag="VXE87_001216"
     CDS             26473..27555
                     /locus_tag="VXE87_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0842762.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            27548..27751
                     /locus_tag="VXE87_001217"
     CDS             27548..27751
                     /locus_tag="VXE87_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0842763.1"
                     /translation="MIKPYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(27876..28195)
                     /locus_tag="VXE87_001218"
                     /pseudo
     CDS             complement(27876..28195)
                     /locus_tag="VXE87_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         8521 a         6212 c         5153 g         8309 t
ORIGIN      
        1 atacccttag aaaggttgat ttaacaatgt tttcaacgct agaaaaaatt aaagaattag
       61 ctaaaaaaag agggattcct ctaacaaaac tagaagaaag tctaggatat agtaccaatt
      121 atttctatac tttaaaaacg aaaaccccaa actctgaaag attgcaacag atcgctgact
      181 acttcaacgt atctacagac tacttacttg gtcgtactga taatcctgct attgctggtg
      241 atgatacaat ctcaggatac acgtctgacg acctccgaaa gatggcagag aatgccaaaa
      301 ccttcgatgg taagccactt acagaagagg atatcgatgc gattcaaaac atcatagaaa
      361 tatacttgag aggtagatag tatgacgatt accgaacaag atgccttgct tttcaatacc
      421 ctttttgaaa acatatatca tcaactcccg tctgttgata gttctaaaga ttattggttt
      481 gtaagggctc aaaaagggca attctataaa agttttcaaa ctggtggcta tatcgccatt
      541 ggatggaact atataacatt agatgacctt aaaaatcttg acgaagatgc aatcaaagga
      601 aaaatcaagg agtttgacag taggatagaa aagcctggtt ctgcctacaa tcaaatgatg
      661 aagtttgcgt atagtcttaa aatcggagac attgtcattg ttccgtcaga atctcctaac
      721 gattttcttg taggtgaaat aacgagcaga ccctatacag agagtgaaag caacatagag
      781 tccgcatcta acgtttgccc atttaataag cgaatgaatg tgcactggtt tggagtcata
      841 ccaaacagag atattgaccc gaaactttac aaattagtct attcaggcca taccatcact
      901 gatgcaaatg cctacaaaaa attcatcaac cgaggtctat atgatgccta catcgatcat
      961 gaccacatga gtatcacttt caaagtacaa gaggaaaaca atattgatgc ttttgaatac
     1021 tcaacatttc tgcacactgt cttgcaaatg gtcaatgttg taaaagaatc tgatgaatta
     1081 aaagatgaga aagtcgttct aagaaccaac gtccaatcga aagggccgat tgaactactt
     1141 ggacatcctg aaatactaat cccggttcta gtatttatca ttattctaac tggaggaatt
     1201 gcttttcgca atttaattaa acgcaatggt gcaaactttg aagttgattc taagcttggg
     1261 aaatttaaag ctcagttaaa tagcgatggg gatgaagcaa tcaaaaaagc ccaggcaaat
     1321 aaaataaatg ccgaggctat tgcattgtta atagataaag ggatgagtcc gcagtttaaa
     1381 ggcgctacat ctcaactaga tattaaagct ccagaagtag caactaggat tcttcaagat
     1441 gaactactcg aatctccaga aaaagtcgaa gaataatttc agaaataacg aaactgagta
     1501 aaacgatgat tggaagtgtt aggatttgtc ttagaaaaaa gtaacaaatc aaaaaaacaa
     1561 atgctgaaac ttgaaacagt acagctaaat gtgcatagag tttcaacttc attttaatca
     1621 cttcctttca attctatttt actctagttc aagagataaa acaactaatt ttaaaaaata
     1681 tttgaaggat gatagcctat gactattgaa gagctagttg actcacacgg tgtcactctc
     1741 gcttactttg ataacgaact ttggcaaaga cctggagttt atatcaaaga aatcagtatt
     1801 atctttataa accgtgaact gtccgaagat gcaaaaaaac gggtcatata ccacgaatta
     1861 ggacatctgg aacattctac tgcactatat caaaacaacc acactaggtg cgagaatgag
     1921 gctaataggc acatgattca taagttgcta gaagaagaac ttgcactatc agacgaccat
     1981 caatctttca actatatcca gttcatgcaa aaacataagc ttagaacagt cacagacgaa
     2041 ttgatggtaa ttgacgaata ttatgaattg ataggatagt tcatcagaat aactataaaa
     2101 acaaaaaatc ctcacactcg ccatcgccaa actttgagtg tgaggatatc cagtatagta
     2161 aaaggcatta aaaagccctt tttactatac ccattttaac aaaaaagtga ggtaaacgca
     2221 atgtggatgg aagaattgcc aaacggcaaa tataaatttt ttgagcgata taaagatcca
     2281 tatactgaga aattaaaaaa agtttcagta accatggaga agaaaactcc ccaggcaaga
     2341 aatcaagctg ctatcttgtt acaagagaag ataaataaaa aactcagcac aaaacaagta
     2401 gaaagcatta catttgaaga aatctataac cttttctata aatcatgggc gcaaacagta
     2461 aaggaatcaa caaaacataa ttgtaaatca gttgataaga agatgaaaga agtcatacca
     2521 tccgatacca tacttgctaa tcttgacagg cgttttcttc aagaggctat tgaaaaaatt
     2581 attgaaagca acggatatat tacagctaaa aaagtacggc ataggctcag aggtatcttt
     2641 aattacgctg ttcaatactc ttacattgaa aacaacgagg tcgattatac tacgattcct
     2701 caaaaaccaa agactttaga agaactggaa aaaaagcgta acaactttct caccatgcaa
     2761 gaaataaaag cacttgtcga tgtccttaat cgtcgagaat atcaccaaaa gtacgctgat
     2821 atggttcttg tgctgacatt aactggtatg agatatggtg agttaactgc cttacaactg
     2881 aagaatatag acttcgaaaa caacaaaatt gagatcacag gtaattttga ttcagtaaac
     2941 aaaatcaaga cgctaccaaa gactacaaat tcaatacgga caatcaaagt atcagagagt
     3001 gtcatagaag ctattcaaag acaaatagta cgacttagcg aacgtttcca gccattgtca
     3061 agcgatgatt atattttctg ttttgaaaaa tggaatcaac ctacaacaat agcttgcttc
     3121 atacagatat taaaaaaata tggaaaacag gccaaaatag aaaaaaattt atctagccat
     3181 atttttaggc attctcatat ttcgttttta gcagagtctg gcctcccaat aaaatcaata
     3241 atggatcgag ttgggcactc aaatgcaaaa atgactttgg aaatctattc tcatactact
     3301 gaagatatgg aggataaact ggtcaataaa ttagatacta ttttttaatt ctgccccttg
     3361 gttgcccctt tttgatttca taacacaaca aaaccccttg aagatattga taattcaagg
     3421 ggttgcttta tatcgttata attcatccgc tatcttattg atttttctga gtctgtgatt
     3481 gacaccactt ttggtcagag gggtgctgag gctatctgcc aactgttgga tagagtagtc
     3541 tgggtgctga atcctcagtt gcgccacttc ctgcaaatct actggcaaat tttctaagcc
     3601 catgatatct tttattttac tgatattgtt aatggtcttc atgctggcag aaactgtccg
     3661 agcgatatta gctgtctcgg cattattagc ccgattgagg tcgttacggg tttctcgcaa
     3721 aatcttaacc cgctcaaaat catcacgtgc ctgcatggct ccgattacta tcaagaagtc
     3781 cataatgtct tctgctcgct ggagataggt cacagccccc ttcttgcgct caagcacctt
     3841 ggcatccagt aaaaactgtt ggagaaggga ggcaattcct tgcgcgtggt ccagataaac
     3901 agaactgatt tccaactggt acttgcctga ctcagggtca cgaatgctcc catttgccaa
     3961 gaaagcgcca cagagatagg cacgacctgc ttcctcatcc gataaaatcg cctcatcaat
     4021 acctgtttcc aggccaaaga aagagtctgc caagtgcaaa tcacttaaca aatcctgcac
     4081 cttttcatct gtaaaaacgg tatagacgcg attcttgcga agattgctcc gttggtggtg
     4141 acgaatttca gatttgattt catagaaatg gagaaaggac tcatagaggt gacgggccag
     4201 tttggcattt tctgtcacaa ctgacaaagt caagcccgaa gtcgagagac cgatgctacc
     4261 agacattttg ataatggcag ataattcatg ccagctcaga tggtgttggc ccaggatttc
     4321 ttcttttact gctactgtga aactcatttt ttcacctgta taatgcgcat caactcgtcc
     4381 acaatcaaat ctccatcgtg gaaggcaccg ccattttcca gacgaaggaa gttagatgaa
     4441 atcacgcgcg aaacttgctt acaaagacct acaaaatcgt gttccacttg caccaagtat
     4501 tcatcaaaac ggttggaatt catgtattcc tgaggcactt tttcaatatt caccaagaca
     4561 gtgtcgataa aagggcgacc aaggtgacga tgcaagactt ccacgtggtc gctatctgta
     4621 aagtgttccg tctccccacg ttgggtcatg atattgcaga cataggcaat ttctgccttg
     4681 gtttccaaaa gagcccgccc aatttcctta atcacgatat tgggcaaaat agaggtaaag
     4741 agagaacctg gccctaggac aatcatgtca ctttcaagga tggtctgcac tactcgacgg
     4801 ctggccagag gcgtatcatc gtttagggca ttggtcacat agacattgtc aattatgcct
     4861 cgatggtcta caatatgact ctctccagcc acttctgtcc catcctgaaa gactgcatga
     4921 agggtcaaag gatggtcact ggaaggataa attttccctg ttgtatggaa aaatttgctc
     4981 aataactgca tggcattata ggttgaaccc tgcatttctg acaagccagc aatgatgaga
     5041 tttcccaatg gatggccagc aaaggctccg gcatcctcag agaaccgata ctgaaagacc
     5101 ttctcataaa acttaggcat atccgacatg gccacaagga cattacgaag atcacctggc
     5161 ggtgtcaact gttgcatatt ttttcggagt tcacctgaag aaccaccatc atctgccacc
     5221 gtcacgatag ctgcgatttc cacatctttt tcccgcagac tttttagaat gacgggaatt
     5281 ccagtccctc caccaatcac cgttatcttt ggttttctca tgaacggttt accgtttcct
     5341 ttctgcggtc tttgtcgcga tgcccttcat taacagacca attcttggat aagtcctgca
     5401 ccaagcgttt agcaaatgcc acactacggt gttgtccacc cgtacatccc atggcaatgg
     5461 tcaaaacgga cttaccttcc ttttggtaac ttggcagaat cggctcaatc aaggccaata
     5521 aatgttgata aaagtcttct gactcaggat ggttcatgac ataatcataa acaggttcat
     5581 ccacacccgt ttggtttctc agttctggta gataataggg atttggcaag aaacggacat
     5641 caaagaccaa gtccgcatca atcgggattc catacttaaa tccgaaagac atgacttcga
     5701 tacggaaaga ctgggcttgt tcttggtctg aaaactgctc tgcaagggtt ttgcgcagct
     5761 cacgtggagt gagttcagtc gtatccacca cattttggct catatttttc aaaggtgcca
     5821 agagttcacg ttccaacttg attccatcta aaatacgacc gtctgctgct agtgggtgac
     5881 tccgtctggt ctccttgtaa cgagcgacca attccttatc agccgcatcc aaaaagagga
     5941 ttttgaaatc caaaccatct tgattttcca actcatccaa aacagcttga atctctgaaa
     6001 agaaagaacg gctacgcata tccactacca aggccaactt aggattgtct tccttaattt
     6061 caaccagctg caaaaactta ggcaagagag ctggcggcat attatcaatg gtgaaataac
     6121 ctagatcctc gaaggactga atggctacag ttttccctgc gccactcatc cctgtcacaa
     6181 tcaccaagtg aagttgtttc tttgtcatct ttttctcctt atatcaaaag aagtttggca
     6241 acaccaaact tcaactagct tatccaatct ctgcgatgac ttcaatttcg acttttacat
     6301 cacgaggaag acgagctacc tccacagctg aacgagctgg gaattcctct ttgaaggccg
     6361 tttggtaaac ctcattaaaa ggaacaaagt cgttcatatc gctcaagaaa caagttgttt
     6421 tgacaacatg gtcaaagtct gttcctgctt ctgccaaaat agcaccgatg tttttcaaga
     6481 cttgctctgt ctgttcttgg atattctctc ctacaatttc cccagtttca ggggataggg
     6541 gaacttgacc gctagcaaac aaaaggttgc caacgatttt tccttgaaca tagggcccga
     6601 tagcctttgg ggccttatct gtatgaattg tttttgccat tttcttttcc tcacaatttt
     6661 tctaagattg catcccaagc ctcatccatc cctgccttgc tgacagatga aaagaggatg
     6721 aaatcgtcac ttgggtcaaa gtttaatttc tttttgattg ctgattcatg cttgttccat
     6781 ttaccacgag gaatcttgtc cgccttggtc gccacaatga tgactggaat ctcataatac
     6841 ttgagaaatt cgtacatctg cacatcatct gctgacgggt catgacgaag gtcaactaga
     6901 ctgacaaccg cacggagatt ttcccgagtc gttaagtact cctcaatcat gcacccccac
     6961 ttttcacgtt cctttttaga aacacgagca tagccataac caggcacatc cacaaagcgc
     7021 atcttgtcat caatgttaaa aaagttcagg agctgggttt taccaggttt tcctgatgta
     7081 cgagcgagat tcttacggtt caacatagtg ttgataaagc tggatttacc aacatttgaa
     7141 cgccctgcta gggcaatctc tggcagttca tcctgcggat agtgggactt attagctgca
     7201 ctgagcaaga tttcagcatt gtgtgtatta agttccatag tcacctctag gctgtttcta
     7261 ggatcggttt atccgttcca tcgacagttt ctttagtgat gcgaaccaat ttcacatttt
     7321 cctgactcgg cacctcaaac ataacatcta gcatggtttc ttcgatgatg gagcgaagtc
     7381 cacgcgcccc tgtcttccgt tcgattgctt tattagcaat ctcttgaagg gcttcgtcgt
     7441 caaattccaa ctcaacatca tcataagaaa gcaaggtttg gtattgtttc accaaggcat
     7501 ttcttggctc tttcaagatg cgaaccaagt catcaacggt caattgctca agagccgcaa
     7561 aaacaggcaa gcgtccaatt aactcaggga taataccaaa tttttgaatg tcttcagcga
     7621 tgatttcttg catgtatgag ctgttttcgt caatcgcctt attgttttga ccaaatccga
     7681 tgactttttc acccagacgt tgtttgacaa tttcttcaat accatcaaaa gcaccaccca
     7741 cgatgaagag gatatttttt gtatccactt gaatcatctc ttgttgtgga tgtttgcgtc
     7801 caccttgagg cggtacgcta gcaacagttc cctcgataat cttgagaagg gcttgttgca
     7861 ccccttcacc agaaacatca cgtgtgatag acacattctc actcttcttg gcaatcttgt
     7921 caatttcatc cacatagata atgccacgct ctgcacgttc gatgttaaag tcagcaacct
     7981 gcaagagttt gaggagtata ttttccacat cctcacccac ataaccagcc tcggtaagag
     8041 ctgtcgcatc cgcaatcgca aaaggcacat ttaagctctt agccaaggtc tgagcaagga
     8101 aagttttccc tgaaccggtt gggccaatca tcaagatgtt tgacttctgc aaatctacat
     8161 cttccgactc ttcacgcgta tcgtggaaat tgatgcgttt gtagtgattg taaactgcca
     8221 ctgccaaggc acgcttggca cgatcttgac cgattacata gtggttcaag atatggagga
     8281 gttcaattgg ttttggtacc tcagacaagt ctgccaagac ttcttccgcc aactcttccc
     8341 gaatgatttc ctgggctaac tctacacatt cattacagat aaaggcgttg ttcccagcga
     8401 ttattttttg tacttcttct tggcttttgc cacaaaatga gcaataaacc atcatatcat
     8461 tattcctagt tgtaggcatg atttccttcc gttctattct atactgtcat tctatctaaa
     8521 ataaggtcat gtaaaaagca tggatactat tgaccaaatt ggtaaaggca tttaaccaga
     8581 gcaggacaga aagtccataa cgctttttac gaaaagcctg tgctcctgca agcaagcaga
     8641 ccaaacacag catggctgtg aaaaaaccaa atatactacg ttccattaga cttcctttct
     8701 cttgcggtat tggatggtaa aatcataagg atttttctca tctttggtat aggatttgct
     8761 tgaaactgtc tcaaaaagag acaaatcaaa ctcctcaggg aaataggtat ctccctccac
     8821 ccgagcatga atttgagtca caatcacttc gtcaaggtag ggttcaaaag cctgaaaaat
     8881 ttgcttccca ccgagaatat aaagattctt ttcttgagcc tgataccagt ccaagacaga
     8941 ctggacatcc tgaaaagtag taaccccgtc tatcttttct tcagaattac gcgtcaaaat
     9001 cagagtttcc cgttgtggaa gcaagcgacg ccctatccca tcaaaggtca cgcgccccat
     9061 caagatagca tgattcagag ttgtttcttt gaagtgttgc agttctgctg gtaaatacca
     9121 aggcagacga ttgtccttac caatcacacc ctcttcatcc tgggcccaaa tagctacaat
     9181 tttcttagtc atgcttccat ccttttcact gatagtacta ttctatcaaa aaactcaaaa
     9241 aaagactggt ttggaatagc ttacaaaata gaaaaaatct gtaagaaatt tcctacagat
     9301 ttatctatgt tgccttgttt cttataaacc aggtgcttgt ccaagttctg ccgcaagcat
     9361 ccaaactgtt ttctcaagtt cagccttagc accaacaaaa atatcgtttg taacatcatc
     9421 gccttcttcg tcagtcacat ccaacgcttt ttggaaaaga gcgatgaggt agcgataaat
     9481 agctagaaca cgttccaaac tttcttcaac attacggtat tcaccagctt cttcttcgat
     9541 ttcactgttt tgaaggaact ctgtcaatgt agagaatggg ctacctccaa gtgtaatcaa
     9601 tcgttcgctg atttcatcta aatgaccatc aagagcatcc atgtactcat ccatttttgg
     9661 atgccatacc ataaaaccgc gtccacgcat ataccagtgt acttggtgca aagcaacgtg
     9721 ggctacgtac aaatcagcaa cagcttggtt caatacttcc tttgtttttg ccaatgctac
     9781 tggcgctgct tttgttaatg ttgcgacatc ttttgctgct tcttttttca attctaccat
     9841 tttattttac ctcattcatt atttttatgt aaccacttct taatgattac taccttagta
     9901 tactactaag gaaaaccaat agcaagacaa agaacttata tgagaaaagt tgcaatagac
     9961 tgataattta agaattcttt agaagacaaa aaagagggtt ggatgcttat agtcaatgga
    10021 aatccatcag caaactagga aactaaaccc agcttgacca aagcacaagt tttgaggtcg
    10081 caggtagaac tgaccaagct gatgtggttt gaagaaattc cccaatacta taatagattg
    10141 aaataagatg aaaccaagtc gattaggaaa ggtaaatgaa tttctaaaat gttttaccaa
    10201 tcacaaggtc tttatctata ttcaatctac tatataagct tcatttccga gcaagatctt
    10261 gaatttactc gaggatgaac tatcataaaa caaagaaaaa gagggtgcta ctatcacatc
    10321 cctctttcaa atcatcgctt aataccaaac gctgacatct acgcgccctt ggattccttt
    10381 catgtattca gaagaggtat attgccaacc tttttctcct gaataataag ggttttccca
    10441 ttctaaagca ttcgtatagg ccgctaccca gtttacatgt tttaaaatat ctgggtgttt
    10501 taaacgcgtc tgtaataaac tacgatagct atagacatac acattttgat aacccgcctg
    10561 cttcatcgtg tccatgtact tgttgatgat tttaacccaa gtatctgtat cacttggagc
    10621 tctcttgctc ttatttacat attcccagtt ctcaacatca taatagatag ggtaagacag
    10681 gttcatattg tatttcttta taagttcaat ggtctgttta gcgtcattct cagcatcggt
    10741 ctcattttca gcataggtat agagatagac accataagga attcccagac gttttaactc
    10801 cttaatgtta tgcgccaatt ccttgtcttc tttaccgcta taacctagac gaacaatgac
    10861 accatccacc tcgttctcat caataacctt tttccaatca ttgatacgac cattgtgctc
    10921 actaatatca atgattttct tagcatgttc ggttcccact tgttcttctc tattattaaa
    10981 gaaatagcgt ttaccatctc tgtgaaccca gccgacattc aaatctttct tttctttgag
    11041 ctcaccagag gccgcaaaga tatagcgagc accatccata atcacttcgt cagtcgccat
    11101 agcaccactt ccagtcaaat agtagttgcc ttgccactca ttccgagcca tatagcccca
    11161 cttcttgaaa tagtaccatt tgccgcccac tttttgccac tcttggttag cataagttcc
    11221 atcggatttt agataaaaat aagcagaata ggctggatca tagagccatt cattttgcat
    11281 catagctcct tgaccattca agaaataact tccttgccat tggcttttag ccatgtaacc
    11341 ccacttcttg aagtagtacc acttatttcc aatcaattgc cattcttgat gagcataagc
    11401 cccatctgac ttgagataaa accaactctt gtaattactg tcatagatcc actcgttttg
    11461 ggccatatat ccacctgatt tcaggtagta atttccatgc cattcattct gcgagtaacg
    11521 accatctgaa ttaatataaa accaagcctt atagtagttg tcaaaaatcc attcactttg
    11581 agctttagaa ccatcatcct ttacataata atccccatcc cagtgggcag cagcattagt
    11641 ctgtacttct gcgctcgttt gcgttttatt agaagactga ttttgctctg aactacttga
    11701 agctgtcgtt gtatcctgcg aagtttttgc tacttcagtt tcatttgcag cgacatgact
    11761 agttgccaag cctagtaaac agatacttgc taatccaatt tttgttttca atctttgctc
    11821 tcctataaaa aatgtaacag acatctgaat gctgttccac ctagcttttg ctacttactg
    11881 attattttac aaagtcaagc aaagccaaga agctttcagc ttcaagtgac gcaccaccta
    11941 caagggcacc gtcaacgtct gggcaagcca tgtatgaagc aacattttca ggtttaacag
    12001 aaccaccgta ttgaacacga actttgtctg cgacttcttg accaaagtca gcagctacaa
    12061 cgtcacgaac aactttacac attttttgtg catcgtcttg tgaagctgat ttaccagtac
    12121 cgatagccca gattggctca taagcgataa ctgaggcagc aacttgttca gcagtcaatc
    12181 cagccaatgc agcagatact tgagcaccta cgaattcagc agctttacca gcttcgtaag
    12241 tttcaagtga ttcaccacaa cagatgattg gaagcatacc gttcgcaaag attgcttttg
    12301 cttttttgtt gatatcttcg tcagtttcat ggaagtagtc acggcgttct gagtgaccga
    12361 taacaacgta gtcagtaccg atttctttca aaacttgtgg gctagtttca ccagtgaaag
    12421 cacctgcatt ttcaaagtag cagttttgag cagcaacttt aaggtttgag ccttttgcaa
    12481 cagcaagaac agttgtcaaa tcaagagctg gagcagcgat acctgcttca acaagatctg
    12541 atgaaggaag ttttgatgca actgcttcaa cgaatgcttt agcttcttct ggatttttgt
    12601 tcattttcca gttaccagcg ataaatggtt tacgtgacat ttcacatacc tcttttttca
    12661 atttattttc tatttattct atcacaatta tacacagctt gcaaatctta ctcggatttc
    12721 aagcctactt gcatggatta atccttccag agatccatgg catttctgaa atctgcagat
    12781 acctgtgtca actgaggatt gcttgcttct ctttctgctc tcttggcctc aatttgagcc
    12841 acactcttga ttccttcatg gcgccagttt ctcaaaatcg cctgaatgta cttccagttt
    12901 ggttttccat tcaaaacagc ttcacgaaga gcctccttaa tcaagtcagc actggttcca
    12961 tcttccttta gtgtcttggt caaatcctca atctcaaaag gcgtcaacaa tcgtcccaac
    13021 tcctgctgga aggtttccac caaatccttg agctggtttt gaggtgttag ctggtctgaa
    13081 cttgaatgaa ctgctccaaa caggtcatcc aaacgttcca aggccaaact agcatcaaag
    13141 agcaattcaa tttcgccatt taattcgata gtacgatact ggagcagtcc cctttccgtc
    13201 agattagaaa tggactggtt gacatccgaa atttccttgc caatcctttc agcaatctgg
    13261 cttggcgaca tttcttctaa gcctgtcgta ttttgcaaat agaaaaattg ccaaaccaga
    13321 aaatcgtcgc tagaaggaaa gagttcctta aaatgcaaga gcagggcact cggtaaaacc
    13381 aaggtacctg atttaaaagc gtctaaatat gtcataattc ctcttataaa tacccatatg
    13441 cagatgcatc atcttctatc tttctccaat caaaaggcgt ctcctgatag accgcatggt
    13501 ttacccaatt actgaaaaag agggctgcag atgaagacca acaaagacaa ggtacctgat
    13561 taacatcatc atctttaaag taattttctg gaatatgtgg gtcgaaacct gcatcacgat
    13621 ctcgaaaata ctcttttgcc aaggtatcac ggtcatactc caaatgacca aaactataaa
    13681 tttctcgtaa atcacgactg gccaaaatag aaaccccaac ctgaggtcct tctgataaaa
    13741 tctcgagatt ggtcttgttt aagacctctt ccttagaaat ctccgtgtgc cgtgaatgag
    13801 gggatacata gctatcatca aagcctctaa atagaaggtg accctctttt agggtgtcct
    13861 gaggataaat acctgatagc ttactgtcca tctggtattt ttctacacca tagcgcagat
    13921 aaagcccagc ctgagccccc caacagatat gaagggtcga atagacatga gtcttagacc
    13981 actcaagcat ctgtctaaat tcctcccaat agtccacttc ctcaaatggt aaatgctcaa
    14041 ctggagcacc cgtgatgatc atcccatcaa aatactcatc cttgacttca ggaaaagttt
    14101 tatagaaggt ctccatgtgc tctgaacgag ttgttttaga acggtggctc tccatataga
    14161 gaaaatcaat atccagttgt aggggtgtat tagccaagtg gcgcaacaac tgggtctctg
    14221 tgaccatttt ctgtggcatg agatttaaaa ttaaaatctt caaaggacgg atatcttggt
    14281 gggcagcacg ttgatcatcc atgacaaaga tattctctgt ccgtaaaatc tcaacagctg
    14341 gcaatttttt atcaattcga atcggcataa ccctctccta actgtactct ttcaggaata
    14401 attgcatatg tttgaagaca aatctcaaac acttagtcct tttattatac tgtaagaaga
    14461 tatagttttc aattatagtt tttctctaac tagttatagt ctatttttat atcctagtgt
    14521 agagaaaaca gccctaggga ctgttttcat taataatgca taagaacttt gtagtcgtag
    14581 tcaccaattt tttcacggcc gttcaattca tccaattcaa caaggaaggc acaacctgcc
    14641 ataacaccac caagtttttc aatcatctcg atagttgcct taacagttcc acctgtcgcc
    14701 aaaaggtcat ctacaataag aacacgttga cctggcttaa tggcatccgc gtgcatagtc
    14761 aaggtatcga caccgtactc tttttcatag tcagcagaaa taacttcgcg tggcaattta
    14821 cctggcttac gaacaggcgc aaaaccaatt cccaactcaa aggcaactgg acaacccacg
    14881 ataaatccac gagcttcagg tcccacgatc atgtcgactt tcttgtcagt agcatactga
    14941 acgatttcac gaacagcgta gctataagca tttccatcag ccatcaaagg actaatatca
    15001 cggaaggtaa tgccttcctt tggataattt tcaattgttg caatgtaatc ttttaaattc
    15061 atctttttct ttctttcaaa gttttttact ctctattata gcatattttt taagaaagaa
    15121 aaaaggaaaa gttaacttca ataattatct aacgttttga cgatttataa ctagccatcg
    15181 caataaagcc caatttctgt ttattcttag caaacatttt atacatagtt aaaaactgct
    15241 ttctattctc ctttttacaa gcatttacac aaattttcaa agttcctagc aaaccttcgt
    15301 cataaatcat acccgataat ttcattaatg tcatttcacc agtcaatgct ttcacatcac
    15361 aataacctga ttctatcatc acctgttccc aaccatcttg agttaaagga cctacattta
    15421 catgaattgc ttgtgataat tcctgtctga tagactcttt agcttcctta agaagcacat
    15481 catgtgtcaa gagaagacct ccaggtttta atacccttag atattccatt acacattttt
    15541 tcttagcttg atcggcttgc atagtcagca tagcttcatt tataacaata tcaaaactag
    15601 catcttgata aggaagtttc attgcatttg ctctttcaaa actgattaaa tgagcaacac
    15661 ctgccgttcc agcagatttt ttagccactt ctaaagcttg agcatccata tcaacagcag
    15721 ttatcttgca accaaaacgc tgtgccaact caattgctgt agttccccta ttacacgcaa
    15781 cctctagtat tctcttttct tttgaaaatc ctccttctgc aattaaccaa tctgtggcac
    15841 gctttccacc tggacgtaag cgttttttcc ccaattttgc taaaaactta tgacctgctt
    15901 ctgacatttg aacacctctg ttttttcttc attataacac aaaatgatat tatctgacaa
    15961 ttctaatcta ttatttgata aactagaatc aaaagcatac aagtcaccat aactatagca
    16021 taaatttatt attacctctc tagttcgaat tcaattgctc acgtagttta cgcatatagc
    16081 ttcacttgta gatggtaccc acaaataata ctcaatggaa atcaaagagc aaactaggaa
    16141 actagccgta agctgctcaa agtacatctt tgaggttgca gataaaactg acgaaatcag
    16201 taatcatacg tacggcaagg cgacgttgac gtggtttgaa gagattttcg aagagtatta
    16261 aagagcatca caatatagat gcataatatg acttctctag caaaaaggag agaagcattt
    16321 tgtttctctc cctagattaa ctgatatctc tccactacaa ttgataaaga gatatctttt
    16381 cttgtagtgc tttgaatttt atttatttta gtagattgtt ttttcagttt ctacatcgaa
    16441 gaagtgtgct ttgttcaagt caaatccaag ctcaactgtt gcacctgttt gcaagtagtc
    16501 acgagcatca acttttgcaa caaactcgtc tttaccaact tggcagtaaa ggtgagattc
    16561 tgaaccaagc agttctgata cagagatagt cgcttttaca acacagtctg ggaatgtttc
    16621 aaggaaagca ggttctgcat tcacgtcttc tggacggata ccaaagatca attcttttcc
    16681 ttcgtagcct ttttcacgaa gaactttcaa tgctccttct ggcactttca aacggaaacc
    16741 gtcagaaaca atttcgctac caaccaattt cacggtgatg aagttcatag ctgggcttcc
    16801 gatgaatcct gcaacgaatt tgttaactgg atttttgtaa acttcttgag gagtaccgat
    16861 ttgttctaca cgtccgatag tacctgtacc agcagggttc ttagtagctg acataataac
    16921 gatacggtct gcaagtgtca tcgcttctgt ttggtcgtga gttacataga tagttgtagc
    16981 tccgatacga cggtgaattt tagcgatttc agcacgcatt gatacacgaa gtttggcatc
    17041 caagtttgac aaaggttcgt ccatcaagaa tactttcgca tcacggacaa tcgcacgccc
    17101 catggcaaca cgttgacgtt gaccacctga aaggtcagct ggtttacgtt ccaagaattc
    17161 tttcaatcca agtatttcag ctgcttcttg aacacgtttg ttaatgtctt ctttgctgta
    17221 tttacgcaat ttcaaaccga aagccatgtt gtcataaaca gtcatgtgtg ggtaaagagc
    17281 gtagttttgg aataccatgg cgatatcacg gtcttttgga gctacgtcgt tgacaactac
    17341 gccatcgata gatgcagtac cttctgtaat gtcttcaaga ccagcaatca tacggagtgt
    17401 agttgattta ccacatcctg aaggtcctac gaaaacgata aattctttat ctttgatgtt
    17461 caagttgaaa tcttcaactg aatagtgttc gctgtttgga tattttttgt aaatattttt
    17521 aagattcaat tctaccatga ggtgaactcc ttttgtcttt tgataattat attatatatg
    17581 aaaacgcttt atatttctat ggcaagatga ccaaaaaaat aaacaagttc tgtgcaactt
    17641 gcacaaaact ttagagaata tcggagaatt tgaagaagat aatctttatt attcttctat
    17701 gacaaaagca gaaacaagga tcagttttcc catattttcg ctgattctcc actacatttg
    17761 actggattct aattttttag agaaatacaa aagagctagc tttagctagc tcttttccta
    17821 tgcggagaga gggacttgaa ccctcacgac ctaaagcggt cacaggatcc ttagtcctgc
    17881 gcgtctgcca attccgccat ccccgcgtcg attactttac tagtatatca acttttggga
    17941 tgcttgtcaa cacttttttt caaatttttt cattttcacc aaccaggtta ctcagaaagt
    18001 tcatttagat tttcatctac taacttagct ccgagtgtat ttttgaaatg acctagggca
    18061 aattgatgat tttcaggcca gatggaagca acagctggtt taacaatctc gatgtcatat
    18121 cctagattat aggcatctat agctgtatgt aggacacaga tatccgtcaa gacacctgtt
    18181 aagataacgg tagacactct acgctctctc aaacgaatat ctaggtcagt ccctgaaaaa
    18241 gctgagtaat ggcgtttatc catccaaaag acacgactgt ctgaaccatg ctcttgataa
    18301 aagatcccca aatctccata taaattccgt ccactcgtcc caatcagatt atgaggagga
    18361 aataacttac tttccggatg gaaacaatcg ttttcttcat gagcatcaat agtaaagaag
    18421 atataatctc ctcgttcaaa agctaatcga gttaccttgc tgatggcatc cgaaatcgcc
    18481 tgagctggag cacctgctgt tagtttccca ctatcagcaa caaaatcttc tgtataatca
    18541 atcgaaatta aagcctttgt cattagtaat ctcttttctt cacttcttca aaaatatctg
    18601 aaatcaagac cttaagatag gttcccttca ttccaagtga gcgactttca ataatccccg
    18661 cagactcaag tttacgaaga gcattgacaa tcacagagcg agtgattccg atacgatctg
    18721 caatcactga cgcagtcaac ttcccttcat ttccatttaa ttcccctaaa attgctgaaa
    18781 cagcacggag ttcggagtaa gaaagggtat tgaccgccat ggtgacagca gtacgacgac
    18841 gaatattttt ctcatcttct tcacgttgga agttaagaag ctgaatccca acaacggtac
    18901 tggcaatctc aacaagaacc aagtcctcat cttcgaattt tttatcatta cgccaaataa
    18961 tcaaagaacc aaggcgaatc cccgatacat gaatcggtgc aatagtcgtc aagccatctg
    19021 gaaaatcatc tctactctca acagggaaaa tactcatatc atgctcaaca ggtaagtttg
    19081 cttctgtttc gtaaatcata ttagcccctt gaacgtagtc atctgggaaa atcttagttt
    19141 ggaagaattg ctctacgcga tctgtatttg ttttataacg cataaaatag ccaagcagac
    19201 gtcccttact attgataatg caggcattgc aatgaataat atccgctaac tgacgcgtaa
    19261 tagcgttgta aggaagctca tcctgcaact gctcctctga gcgtttcaaa attgatgtaa
    19321 tttttctagt tttttctaat aaatgtgcca tttttcacct cgaatttaat cgctatcatt
    19381 ataacataaa aacgtctctt tttcaataat tatctgaaaa ttccttattg acttgcattg
    19441 acttacaatt taattaaaaa ccagaatatt tttaattaaa ttgttccttt tctattgaca
    19501 agttgcctat ttttgtgtat tataacatta taaaagataa tataataatt ttatttgtct
    19561 tttcacattc ggtctcctta tataaaaaag cgattcattt tgaaccgctt tttcttattt
    19621 atcgcctttg ttacgaataa caaagcctgt ttgcttttcg cttaaagtat tgcgtggttt
    19681 tttattatcc ttacggtaac gtttttcctt atcaaaacga tcgttgccac gacttccttt
    19741 tttgaactca tcacggcgac cattgccacg gcgatcacgc tctcgacggt cgtccccacg
    19801 acggcctcca cgacctccct tagctttacc accgaaacca ttacctgatg gtttaaacgg
    19861 tagtggtttt tcacgtgcaa tctccacttc tggaaggcta tctgggtctt ggactgtcag
    19921 actcaagata tacattgcca attcttctgg agtaaactca gcagccaatt tgcgagcatc
    19981 cttaccaaat ttctcaaagt tggcacgaat ggtttcatct gcaaaatcac gttcgatttt
    20041 cttgagagct acctgttttt ttgattggaa ggattcttct acacttgcag gtttgagacc
    20101 tttcatgcgt ttcttagtca agttttcaat gatttgaagg taacccattt cgtttggagc
    20161 aacaaaagta atagattgac ctgacttacc agcacgacct gtacgaccga tacggtgaac
    20221 ataactctca ggatcttgtg gaatatcgta gttgtagaca tgggtcacac ctgaaatatc
    20281 caaaccacgc gctgcaacgt ctgtcgcaac caaaacatca agattgccat ttttaaagtc
    20341 acgaaggaca cgaagacgtt tgttttggtc taggtcgcca tgaattcctt ctgcacggaa
    20401 gccacgaatt ttcaaaccac gagtcaattc atccacacgg cgtttggtac gaccaaatac
    20461 aatagcgagt tctggttgtg ccacatccat gagacgagtc atggtgtcaa atttttcttg
    20521 ttccttaaca cggatatagt actggtcaac caattctgtt gtcaattcct tagccgcaat
    20581 cttgacatgt tcaggggctt tcataaactg aacaccgata cgtttgatgg catctggcat
    20641 agttgctgag aaaagcaaag tttgacggtt ctcaggtaca cgggaaataa tggcttcgat
    20701 gtcttcaagg aagcccatgt taagcatttc atccgcttcg tcaaggataa gggtttcaat
    20761 gtcttgtaat ttcaaggcct tgcgtttaat caagtccaag aggcgacctg gagttcccac
    20821 cacaatatgg gcaccagatt taagagcctt aatttgtttt tcaatgcttg atccgccata
    20881 tactgaacgg actttgactc ccttactacg accaaagcgg aagagttctt cttgactttg
    20941 gacagctagt tcacgagttg gagcgatgac caaggcttgg atagtcgctt cttctgtacg
    21001 gattttttca agggtaggca agccaaaggc tgcagttttt cctgtaccag tctgagcttg
    21061 accgataaca tccttgcctt caagggccaa aggaatagtt tgttcttgga taggactagc
    21121 ttctacaaaa ccagcttttt caatttctgc tagcaaatca gcagacaagt ttaattcatt
    21181 aaatttcacg ttattcttct ttctaaaggt ggtgcgaagc caccctatag ggcttagttt
    21241 atacttttct ttttatgacg tattttcata taactagata taaaatcgtg ttgcttcttt
    21301 tccacaaaag aaaagtactg ttttctttgc aacctatcta gtataacaca agaccagagc
    21361 aaaagatagc cccatttcta cagaaaatca tgtaagcgct ttttgacttt cttttttgat
    21421 tgaacgacct agataataag acaaagccaa ggcgatactg tataaaatga gaaaaacgaa
    21481 caaggtttgt gtgtacgaat gagccatttt ataagtctct gctaataaaa taggtcccgc
    21541 taaaccagcc attgcccaag ctgttaaaat ataaccatgc agagcggcca attccttggt
    21601 tccaaaaata tcactgagat aagctggaat caaagaaaaa ccagctccat agcaagtcat
    21661 caaaatagac atagcaacta caaataaaac ggaatctgta aagagccaaa gtgagagaga
    21721 aaagaaaaga ttgacaagca gtaatatact aaaggttaga gggcgaccga tatagtcaga
    21781 caaactcgcc cagagcaagc gaccaaatcc attgaaaatc cccaaaacac ccaccattac
    21841 tgctgcatga cttgtagaca agccagccat ctcctgtgcc attggcgatg ccgctgaaat
    21901 taagcctaaa ccacaagcta tgttgataaa gaaaataatc caaagcatat aaaaccgatt
    21961 gctttttaga gcctgatttg cagccattcc ttgcgtcaaa gaggctgttt tttctttccc
    22021 tgaagaagat aaaattgcaa gctcttgctc atttggacgc ttaatgaatt gtgaagctag
    22081 gagcatgata ataaagtaac ttgctcctaa aatataaaaa gtttctacaa gccctacccc
    22141 tgcgatgagg tgttgcgcta tgggactagt caataaagaa gcaaaaccaa accccataat
    22201 cgctaaacct gttgcgagac cacgtttatc aggaaaccat tttataatcg tcgacacagg
    22261 ggtaatatag cctgctccca aaccaagccc acctaaaatg ccataagcga gatacaacaa
    22321 ccacagctcc tgacggtcta ttgcaaatcc tgttaagata tttccacctg cgtatagaaa
    22381 agcagataga cttcccatga ctttcggacc aaatttttct accaaacgcc ccataaatgc
    22441 agccgataag cccaaacaaa agattgctag actaaaggcg aaggcaacag aagcctgatc
    22501 ccatcccgtt ttttcaataa tagggttacg ataaacactc caagcataag tcgaacccag
    22561 cattaagtgt aaaatgaccc cagcaaaggc aataatataa cgattcgatt tcataaaacc
    22621 tcctattttc gaacatttat tctatcttat ataaaaatag ataggatttt agtttatcaa
    22681 gcttgtcaaa aaattactag ttttttgtct ggaaagcgtt tttatctttt tctgtctttt
    22741 ccgtagcaga attgtgcaaa agtttttttc ttgtgctaga atgaaattcg aataggagga
    22801 agataaatgt taacatacga tttaattgtt attggatttg gtaaagctgg taaaacacta
    22861 gcaggtaaat tggcttcagc tggcaaaaaa gttgccctcg ttgaacgcag caaggctatg
    22921 tacggtggaa cttgtatcaa cattggttgt atcccaacta aaaccttgct agttgctgct
    22981 gaaaaggact tgtcttttga agaagtcatt gctactaaaa acacgatcac tggtcgcctc
    23041 aacggtaaaa actatgcgac tgttgctggt acaggcgtag atatctttga tgcggaagct
    23101 cacttccttt caaataaagt catcgaaatc caagctggtg atgaaaagaa agaactgact
    23161 gctgaaacaa tcgtcatcaa cactggtgct gtttcaaacg tcttgccaat ccctggactt
    23221 gctacaagca aaaacatctt tgactcaaca ggtatccaaa gcttggacaa attacctgaa
    23281 aaacttggaa tccttggtgg cggaaatatc ggtcttgaat ttgccggcct ttacaacaaa
    23341 cttggaagca aggtcacagt cctagatgcc ttggatacat tcctacctcg tgcagaacct
    23401 tccatcgcag ctcttgctaa acaatacatg gaagaagatg gcattgaatt gcttcaaaat
    23461 atccatacta ctgaaatcaa aaacgatggt gaccaagtgc ttgtcgtaac tgaagacgaa
    23521 acttaccgtt tcgacgccct tctctacgca actggacgca aaccaaatgt agaaccactt
    23581 caacttgaaa atacagatat tgaactaact gaacgtggtg ctattaaagt agacaaacac
    23641 tgtcaaacaa acgttcctgg tgtctttgca gttggagatg tcaacggtgg ccttcaattt
    23701 acttacattt cacttgatga cttccgtgtt gtttacagct accttgctgg agatggcagc
    23761 tacacacttg aagaccgtct caatgtgcca aatactatgt tcatcacacc tgcactttca
    23821 caagttggtt tgactgaaag ccaagcagct gatttgaaac ttccatacgc tgttaaggaa
    23881 atccccgtta cagcaatgcc tcgtggtcac gtaaatggag accttcgcgg tgccttcaaa
    23941 gctgttgtca atactgaaac aaaagaaatt cttggagcaa gcatcttctc agaaggttct
    24001 caagaaatca tcaacatcat cactgttgct atggacaaca agattcctta cacttacttc
    24061 acaaaacaaa tcttcactca cccaaccttg gctgagaact tgaatgactt gtttgcgatt
    24121 taagttgaga tttaatcgta tcgaacagcc ctctttgggc tgtttttact tctgcggaat
    24181 ctcaaatctg tctttctcct cttttatgat ataatagaaa catgaactta aaaactactt
    24241 tgggccttct tgctgggcgt tcttcccact tcattttaag ccgtcttggc cgtggaagta
    24301 cgctcccagg taaagtcgcc cttcaatttg ataaagatat tttacaaaac ctagctaaga
    24361 actacgagat tgtcgttgtc actggaacaa atggaaaaac cctgacaact gccctcactg
    24421 tcggcatttt aaaagaggtt tatggtcaag ttctaaccaa cccaagcggt gccaacatga
    24481 ttacagggat tgcaacaacc ttcctaacag ccaaatcttc aaaaactggg aaaaatattg
    24541 ccgtcctcga aattgacgaa gccagtctat ctcgtatctg tgactatatc cagcctagtc
    24601 tttttgtcat tactaatatc ttccgtgacc agatggaccg tttcggtgaa atctatacta
    24661 cctataacat gatattggat gccattcgga aagttccaac tgctactgtt ctccttaacg
    24721 gagacagtcc acttttctac aagccaacta ttccaaaccc tatagagtat tttggttttg
    24781 acttggaaaa aggaccagcc caactggctc actacaatac cgaagggatt ctctgtcctg
    24841 actgccaagg catcctcaaa tatgagcata atacctatgc aaacttgggt gcctatatct
    24901 gtgaaggttg tggatgcaaa cgtcctgatc tcgactatcg tttgacaaaa ctggttgagt
    24961 tgaccaacaa tcgctctcgc tttgtcatag acggccaaga atacggtatc caaatcggcg
    25021 ggctctataa tatctataac gccctagctg ctgtggccat cgcccgtttc ctaggtgccg
    25081 attcgcaact catcaaacag ggatttgaca agagccgtgc tgtctttgga cgccaagaaa
    25141 cctttcatat cggtgacaag gaatgtaccc ttgtcttgat taaaaatcca gtcggtgcaa
    25201 cccaagctat cgaaatgatc aaactagcac cttatccatt tagcctatct gtcctcctta
    25261 atgccaacta tgcagatgga attgacacta gctggatctg ggatgcagac tttgaacaaa
    25321 tcactgacat ggacattcct gaaatcaacg ctggcggtgt tcgtcattct gaaatcgctc
    25381 gtcgcctccg agtgactggc tatccagctg agaaaatcac tgaaacgagt aatctggagc
    25441 aagttctcaa gaccattgag aatcaagact gcaagcatgc ctatattctg gcaacttata
    25501 ctgccatgct ggaatttcgt gaactgctgg ctagtcgtca gattgttaga aaggagatga
    25561 actaatggtt tatacttcac tttcctcaaa agatggcaat tacccctatc agctcaacat
    25621 tgcccacctc tacggaaatc tcatgaatac ctacggggac aatggaaaca tcctcatgct
    25681 caagtatgtg gctgaaaaac tgggagccca tgtgaccgtt gacatcgttt ctctccatga
    25741 tgactttgat gaaaatcact acgacatcgc ctttttcggt ggtggtcaag actttgaaca
    25801 aagtatcatt gcagacgacc tacctgctaa aaaagagagc attgacaact acatccaaaa
    25861 cgacggtgta gttctggcta tctgcggtgg tttccaacta ttgggtcaat attatgttga
    25921 agcttcagga aaacgtatcg aagggctagg ggtcatggga cactacacgc tcaaccagac
    25981 caataaccgt tttatcggtg acatcaagat tcacaatgaa gatttcgatg aaacctacta
    26041 tggatttgaa aatcaccaag gccgtacctt cctctctgat gaccaaaaac cgctgggaca
    26101 ggttgtctat ggaaatggaa acaacgaaga aaaggtcggt gaaggggttc attataagaa
    26161 tgtctttggt tcctacttcc acggacctat cctctctcgt aatgccaatc tggcttatcg
    26221 cctagttact actgccctca agaagaaata tggtcaggat atccaactcc ctgcctatga
    26281 ggatatcctc agccaagaaa tcgctgaaga gtacagtgac gtcaaaagca aggctgactt
    26341 ttcttaaaca aaggaaaatg atatcaaaga actccgttat cttgtcggag ttttttgtct
    26401 tttcttttac ccttctccct tgcattttct ctcatttttt gccaaaatag aggggtagaa
    26461 agaaggtagc atatgtctaa attacaacaa atcctaacat atcttgaatc agaaaaacta
    26521 gacgtcgctg tcgtatctga ccccgtcaca atcaattacc tcactggttt ttacagtgat
    26581 ccccatgaac gccaaatgtt cctctttgtc ctagcggatc aggaacctct cctctttgtc
    26641 ccagctcttg aagtagaacg tgcaagtagc accgtttcct tcccagtagt gggctatgtc
    26701 gattctgaaa atccatggca aaaaatcaaa catgctcttc cacaacttga cttcaaacgt
    26761 gtcgctgttg agtttgacaa tctcatcttg accaaatacc atggtttgaa aacagttttt
    26821 gagactgctg agtttgacaa cctcactcct cgtatccaac gcatgcgcct catcaaatca
    26881 gctgatgaag tgcaaaaaat gatggttgca ggtctttatg ctgacaaggc tgttcatgtt
    26941 ggttttgata atatttctct tgataagact gagacagata tcatcgcaca aattgacttt
    27001 gccatgaaac gtgaaggtta cgaaatgagc tttgatacca tggtcttgac tggtgataat
    27061 gctgcgaatc cacacggcat tccagcagct aataaggttg aaaatgatgc tcttctcctc
    27121 tttgacctgg gtgttctggt caatggctat gcgtcagata tgactcgtac agtcgctgtc
    27181 ggcaaaccag accaattcaa gaaagatatt tacaacttga ctcttgaagc ccaacaagct
    27241 gctcttgact ttatcaagcc aggtgtgact gctcatgaag tggaccgcgc tgcccgtgag
    27301 gtcatcgaaa aagctggtta tggtgagtac ttcaaccacc gtctcgggca tggtatcggt
    27361 atggatgtcc atgaattccc atctatcatg gaaggaaacg acatggtcat cgaagaaggc
    27421 atgtgcttct ctgttgaacc aggtatctat atccctggta aagtcggtgt tcgtattgaa
    27481 gactgcggtg ttgttaccaa ggatggcttc gacctcttta caagcaccag caaagatttg
    27541 ctttattttg attaaaccat atagccccta tgctttcctt tcaaaatatc taggggctat
    27601 tttattgtca tttttctgct attatgctaa agaaattggc tgcaataatc taaccctaag
    27661 tgtctggaat gataacgagg gtgctctccg cttttatcaa agacaaggga tgaaacccca
    27721 agaaacaaca atggaaatga taattgatta agaagtcatc tatcaaaaga tgttagaaaa
    27781 agttcaattt cactagaaaa tgaggaaaat cttcccacaa taaaacgcat actatcaggt
    27841 attgtgtact gaccccaaac agttagacaa ttaatttatc cgaaggattt agttctgtac
    27901 tgcacaggac taagtccttt tagttttacc ttaattcgtt tgttgttgta gtaatcaata
    27961 tagtctacaa tagcttgttc caattgctta agcgactgaa acgacttaaa acatttccga
    28021 tttcagaatc ccaaagaagg actccatcat accgttgtct gggctgttgc ccttacgtga
    28081 catggatgct tgaattccct tactctctag aaaccgatga taagaatcgt gttgatattg
    28141 ccagccttgg tccttatctg ttttgtctag ctgtttcaag tgatagtagt aggtc
//
LOCUS       DAVLIK010000025        26300 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLIK010000025 DAVLIK010000000
VERSION     DAVLIK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26300
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.025"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(20..1978)
                     /gene="ftsH"
                     /locus_tag="VXE87_001219"
     CDS             complement(20..1978)
                     /gene="ftsH"
                     /locus_tag="VXE87_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0842764.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMSGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1994..2536)
                     /gene="hpt"
                     /locus_tag="VXE87_001220"
     CDS             complement(1994..2536)
                     /gene="hpt"
                     /locus_tag="VXE87_001220"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0842765.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2540..3817)
                     /gene="tilS"
                     /locus_tag="VXE87_001221"
     CDS             complement(2540..3817)
                     /gene="tilS"
                     /locus_tag="VXE87_001221"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0842766.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3814..5082)
                     /locus_tag="VXE87_001222"
     CDS             complement(3814..5082)
                     /locus_tag="VXE87_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0842767.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5202..5570)
                     /locus_tag="VXE87_001223"
     CDS             complement(5202..5570)
                     /locus_tag="VXE87_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0842768.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5563..5829)
                     /locus_tag="VXE87_001224"
     CDS             complement(5563..5829)
                     /locus_tag="VXE87_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0842769.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5897..9421)
                     /gene="mfd"
                     /locus_tag="VXE87_001225"
     CDS             complement(5897..9421)
                     /gene="mfd"
                     /locus_tag="VXE87_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0842770.1"
                     /translation="MVTLLDLLSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKRKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNK
                     KDYEILEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9422..9991)
                     /locus_tag="VXE87_001226"
     CDS             complement(9422..9991)
                     /locus_tag="VXE87_001226"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0842771.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10062..11177)
                     /gene="ychF"
                     /locus_tag="VXE87_001227"
     CDS             complement(10062..11177)
                     /gene="ychF"
                     /locus_tag="VXE87_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0842772.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11297..12463)
                     /locus_tag="VXE87_001228"
     CDS             complement(11297..12463)
                     /locus_tag="VXE87_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0842773.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKGGATVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLY
                     KARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHA
                     SILLNAGLPYKEIQIRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS"
     gene            complement(12559..13011)
                     /locus_tag="VXE87_001229"
     CDS             complement(12559..13011)
                     /locus_tag="VXE87_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0842774.1"
                     /translation="MDKINYFSAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQ
                     NDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGIKFLTINHLDYLIPFFIETME
                     NIVLWVAMGLIDFNFLKEIISSILYYEELTEKVKEKLVQIALAEENNK"
     gene            complement(13011..14015)
                     /locus_tag="VXE87_001230"
     CDS             complement(13011..14015)
                     /locus_tag="VXE87_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0842775.1"
                     /translation="MTDLTTSQIERQNILNNSLALQKAEEILKVPGFYFEDTFYFTNS
                     QLATFFEVDIRTIERLVEAHKTELTENGYHTLRGEKLAKFKENAFATDTNVGSKVTQL
                     SISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTA
                     LEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNARA
                     TMYSEVLIVIASFEKGVAYEIEQKSKSSNQKLTNTDVIEIIQRLANHPMQEPHLMHAR
                     EKMASRDLSFRNAKHEKLAEYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
                     "
     gene            complement(14164..15120)
                     /locus_tag="VXE87_001231"
     CDS             complement(14164..15120)
                     /locus_tag="VXE87_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842776.1"
                     /translation="MAKNSPQDLENREYFSKRLNLLMEQKGVRQIDLHNALDIPKSTI
                     TGYVKGKSLPTAGNLQKIADFLNVKKSFLDLRFIDTVSTSTLKELLDNNQREKVFEMF
                     FNKIKEILSFKKDYMNMEYIRGKIAFDQGVLGRVLQSSIINPGIVEIFNGLDLSDISK
                     NNEALLLSKQREAREYAYNNVLTMITNEYITRLINVIEREQALNTSYVHSEISNLINS
                     LNNKIDSYGAVVFEVNEIIEKIGIQDRKILGYCLQRKISSVQNEINDLVHNNTNNSFC
                     VTKNKIFTEKSDIIDTIEFDYYKGIQNRLNDLAEEIREHFSD"
     gene            15277..15510
                     /locus_tag="VXE87_001232"
     CDS             15277..15510
                     /locus_tag="VXE87_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842777.1"
                     /translation="MEQWTLKACRVNAGYTLRQVAKKVNKNFQTVSKYEKDSTYIPFE
                     LLKELSAIYQVKLDNIFLGDSTKKIELNKRELQ"
     gene            15600..16226
                     /locus_tag="VXE87_001233"
     CDS             15600..16226
                     /locus_tag="VXE87_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEV0842778.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIKTWEAKPKHAHSTMNNLLLKAVTDMNAKQLVKSRGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSV"
     gene            16678..17130
                     /locus_tag="VXE87_001234"
     CDS             16678..17130
                     /locus_tag="VXE87_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842779.1"
                     /translation="MTETTYENLTRRINRISAEMQEIGEKNGLSRLSLLASQTKFIKE
                     ELSRLLWIELPELNDSHKIEAVSKSTTGMFFHPGIFEMDAMRQAFFKRQAMHFFENEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            17127..17327
                     /locus_tag="VXE87_001235"
     CDS             17127..17327
                     /locus_tag="VXE87_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842780.1"
                     /translation="MTLDLDNMTQAEFDKQMAEIKERNPNIFQLISDFLDRKVTPEEV
                     DEFLKMERAEQVEYIKNYQARV"
     gene            17329..17544
                     /locus_tag="VXE87_001236"
     CDS             17329..17544
                     /locus_tag="VXE87_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842781.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPDYGRYIQLAGVNVWGGME"
     gene            17541..17834
                     /locus_tag="VXE87_001237"
     CDS             17541..17834
                     /locus_tag="VXE87_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842782.1"
                     /translation="MSYTMNLYPDIEKIPDETYFTKEIFLATCLNNTIRIAVARGVLT
                     SQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFVNKSKGEEGLDESIRE"
     gene            17815..18156
                     /locus_tag="VXE87_001238"
     CDS             17815..18156
                     /locus_tag="VXE87_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0842783.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            18149..18424
                     /locus_tag="VXE87_001239"
     CDS             18149..18424
                     /locus_tag="VXE87_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842784.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEAREKVPPRLTKLINRVELK
                     EELKISDNTLNKWESQGLRRYQPPDDGARIIFYLVDDIRRFMGVENG"
     gene            18564..19424
                     /locus_tag="VXE87_001240"
     CDS             18564..19424
                     /locus_tag="VXE87_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV0842785.1"
                     /translation="MTIYEARGFQSNLVYPFDKMEPFQYIERFKPLVVPESADPEEYK
                     RTQAPYCLSGKVMPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLF
                     NGFGDEGGRNVAVTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            19477..20946
                     /locus_tag="VXE87_001241"
     CDS             19477..20946
                     /locus_tag="VXE87_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEV0842786.1"
                     /translation="MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVTEKV
                     AMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDV
                     RIKPREWPQIKLMVRTLAKIRKPLESANLVPVKNGIIDLRTKELLPFSPKYVITSKIS
                     TAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAIFYG
                     DGNNGKGTFQRFLINLIGESNISALKPAQFGEKHNLETLVGKVCNIGDEAPNEYLKNP
                     SDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVPFNA
                     DFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDNDYL
                     LSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQLTP
                     NRYSLRKKRVPSEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            21287..21454
                     /locus_tag="VXE87_001242"
     CDS             21287..21454
                     /locus_tag="VXE87_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842787.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEINDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            21537..22067
                     /locus_tag="VXE87_001243"
                     /pseudo
     CDS             21537..22067
                     /locus_tag="VXE87_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22138..22637
                     /locus_tag="VXE87_001244"
                     /pseudo
     CDS             22138..22637
                     /locus_tag="VXE87_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            23324..23734
                     /locus_tag="VXE87_001245"
     CDS             23324..23734
                     /locus_tag="VXE87_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0842788.1"
                     /translation="MTPEQVKEKLEGVKWINKEIEGLYLELAALESGIIKKQELSNTR
                     VQTSRVNTTENNPISVLKLKEDTLQRIERLNEERMEISRLIDKLANPLERSVLRLFYL
                     NVLDAWQVAEEIDKSKTAVYIIRQKAIEHLANVG"
     gene            23890..24282
                     /locus_tag="VXE87_001246"
     CDS             23890..24282
                     /locus_tag="VXE87_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0842789.1"
                     /translation="MELDKFKTMMNVRERMTYFLRFQRMAGSENQVTIDEEAWKLVLP
                     YRWDLSGEHEKAIREGLEIFAQDINSIENKRARKYFIIHYCYMRKKTMSECVEMAATS
                     STSYHRYKQIAVLNFARIHQNGELEVYK"
     gene            24336..24494
                     /locus_tag="VXE87_001247"
     CDS             24336..24494
                     /locus_tag="VXE87_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842790.1"
                     /translation="MIEDFLIDLENIQLEDMEIDFNMDIDIDLNIDFEIDVDLDDLDL
                     TLLQELEA"
     gene            complement(24923..25117)
                     /locus_tag="VXE87_001248"
     CDS             complement(24923..25117)
                     /locus_tag="VXE87_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0842791.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANCWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(25182..>26300)
                     /gene="dnaN"
                     /locus_tag="VXE87_001249"
     CDS             complement(25182..>26300)
                     /gene="dnaN"
                     /locus_tag="VXE87_001249"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0842792.1"
                     /translation="NKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNG
                     QISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTS
                     GKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVH
                     FVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEI
                     FFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLS
                     SATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKA
                     LNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
BASE COUNT         8353 a         4904 c         4731 g         8312 t
ORIGIN      
        1 gctccagcct ctctcagggt tatttttcgt cattcatttt tgactttact tcatcatagg
       61 atagtgcatg agattcctct tctactgctt caggcatctt tcctgtttcg taaagagctt
      121 taatttgtgt actatccaat gtttcgtatt tcaataatgc ttctgcaatt aacttgtgag
      181 tttcacgatt tgactgaata atttcagcag ctttatttcg tgcctcattt aataatgaac
      241 gaacctcttc atcaatttca taagctgttt gttctgaaat tgatttttga ggactctgtg
      301 caccagacat agcatggttt ccttcatatt gtactgggcc aagtttttca ctcataccgt
      361 actctgtaac cattgcacgc gccatttgtg tcgcttgttc aaagtcgttt gaagctcctg
      421 tagtttggac attaaagata atttcttcag ctacacgtcc acccattaag ccagccaatt
      481 gctctttcat atcttcttta gatagaagca tttgatcctc tttaggaagt gcaatcatgt
      541 atccgcctgc acggccgcgt ggtacaattg taaccttatg gacaacgcga gcattcgaca
      601 agactagacc aacaatggta tgtcctgcct catggtaagc aaccaattct cgttcttttt
      661 gtgaaactgt cttatctttc ttagaaggtc cagcaataac tctatcttct gcttcatcaa
      721 tatctgaagc atcaattatc gatttattgc gacgagcagc aactaaagct gcttcattca
      781 agacattctc taaatcagca ccaacaaagc ctggagtttg ttgagccact aatttcaaat
      841 caacatcttc tgctaaaggc ttgttcttag cgtgaacttt caagattgct tcacgacctt
      901 taacatcagg acggccaacc aatacttttc tatcaaaacg tcctggacgc aaaagggcag
      961 gatcaagtac atctgaacgg tttgtcgcag cgatgacgat aatcccttca tttccctcaa
     1021 aaccatccat ctcaatcaaa agttggttca aggtttgttc acgttcgtca ttacctccgc
     1081 cgagaccgac tccacgttga cgtccaacag catcaatttc atcgataaag atgatagctg
     1141 gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg actagctcca actccgacaa
     1201 acatttctac aaagtcagaa cctgagatac taaagaatgg aacacctgct tctccagcga
     1261 ctgccttagc aagcaaagtc ttacctgtcc ccggaggtcc ctccaaaaga acacctgctg
     1321 gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt taagaactca acaacttcaa
     1381 ctagttcttg tttttcttcc tcagctccag caacatctga aaatcttact ttaatatctt
     1441 ctttatttgc tgctttagcc ttactacgtc caaaactcat tggattacgg ccattgcctc
     1501 ctcccatatt tcccatcata gagaatagga agaagaatag aattccaaat ggcacaatgg
     1561 atacgagtag attaatccat ataccacttg aactttcatg cttaacagtt acttctgctt
     1621 tatggtcagt agcaagtttt tgcaattctg atacggtagt atctgcagga agaatagtgc
     1681 tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa ctgaatgcct gttccttctt
     1741 tacttgtttt aggattttta tagacaccag aaacttcgat aacactacca tttggttggt
     1801 aagttaattc ttttacatta ccatcggtaa tttcttgtac caactcagta tagttgattt
     1861 gctgacttcc tcctgagtta ttcccagaat agaaatactg gaatcctgtc acaaggaaaa
     1921 agataaataa taaccataga aaaggatttt taattaaacc attattttgt tttttcatta
     1981 aagattattc tttctaattt gaatacactt cctctttcaa tactccaata taaggaagat
     2041 tacgataatt ttctttgtag tctaaaccat aacctactac aaactcattt gggatagtaa
     2101 agcaggtata gtctgcctca atttctacaa cacgtccttc tggtttatcc aacaaggttg
     2161 caattttaac agaagctgct tctctttctt taaacatatc tcgcaaattc ttcaaagttt
     2221 gacctgtatc aatgatatct tctacaaata gaacatgtct tcctttgata tcttgagtca
     2281 catcttgttt aatattgata acaccactac ttgctgttcc accatggtag ctagaaacca
     2341 tcatgaagtc catttcaata tgtgtatcaa tatgtttgac caattcagcc ataaaaggaa
     2401 tagatccttt taaaatccca actaagattg gattttttcc tgcatagtct ttagttaatt
     2461 gagcacctag ttttttagct gcttctgtaa tttcatcgtg tgaaacgagg acttttttaa
     2521 tatcgttttc taacattttt tacctatcta ttttttctat ataaagtaca gtgttcatta
     2581 tatcattttt cgttttttta ctcaaattat tggtcgcaat tcccaaaatt gagacaattt
     2641 caccaaattg ctcaataata agagcagagt ttctcttttc catagggatt ttcaaatcaa
     2701 taaataaacg tctgagtttt tttctatgcc cattttgaat caaaacatct cctgtttttc
     2761 gatgacgaat gtgtatggat gtttcacgtg aaacaggtat ttgttgaatt gattcacctt
     2821 ctaatggaag tccaaaggaa aataaatatc cttgataagc tacctgattt tgatagtgta
     2881 acacaagttc atcttccttt tcatcagcct gcggactgat tttacaaatc tgaaactgtt
     2941 ggtactcttt tatcaattca tagccatttt taatcggatg acgatactgg cttttagatt
     3001 ttaaaatctg ctgaacttca gcaaactgag cttttgtaag attcaaatct ggaaaacgat
     3061 tcagataagt ttgaagtaaa actctttgtg tagactcaga gtaagaaaat aactgctgta
     3121 aatcttccac attaatattg ttagataatt cagctattgc caaatcataa tctaaaattt
     3181 cattgccaat gcctaagatt gcatccctaa atcgaggatt ttctttttcc aattctggta
     3241 agtaagagtt tcgaatacga tttcgaaaat aatgattctc ctgatttgat gtatcttcaa
     3301 agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa gaagggacga atgatttcta
     3361 tctctccgac tacttgcttc tccttaattc ctgatagata gcgcaagcga gttcctcgaa
     3421 tcaagcgcat caaaatcgtt tccacctgat catcagcatg gtgggcagtg actaaagctg
     3481 tcgcacctgt ctttttcata acctcttgaa aaaaatcata acgaaaattt cgtgcacgcg
     3541 cttctgaaaa ttctcctgaa aaattgctga tataaatagg aagctctgct tcagcagcca
     3601 acttccttaa ttccttttct tcccaatctg attcaattct ctgcttatga ttcacatgag
     3661 ccagaatcaa ttcaatctct aactcttttt gataagtaga caatacctta aatagaaaca
     3721 tagaatctaa tccaccagaa agagctagaa ccgccttagc atgctttttg aaatatccct
     3781 tcttgagaaa atgatttaaa aaatctggtt ccctcatttt agaacctcat aaacatcctt
     3841 ggctatctta gaaatcgtat cataatcaga attcttagtg aaaatagaaa gaataaatgg
     3901 agaatctgca tagacaacac ccgtatcatg cttaaattca tccgcatctc caattttatg
     3961 agctacttta acagaaacac ctttggcaat tcgctgacta tcaaaatctg ttttagtcaa
     4021 agactctagc acaaatccat tttgattata aatagcttcc ataaacttcc cggccatctt
     4081 agaagaaatc aatttttctt ttggatccca atcatctccc ataatggcag acatcttgga
     4141 tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc aatagattat gagctacatt
     4201 atcagattct tttgatactt tcgtaattaa atcctttaaa gaatattctt tattatcttc
     4261 ttttttagga agactaccac ttccctctgg tttataagaa cctggaaaat cattgactgc
     4321 agatacgtat tttacagtcg tatctaactg ataaagaccc tcatttattt tttcttgcgt
     4381 ataatagaga taggagagtt tcaaaacgct ggctgcatac atcttttcat cttgattgat
     4441 accagcttct tttccagtag tcagttgctt aacataaata gagaaagaat ctttctgata
     4501 tttttcagat aacatttctt gaactttact catccgatta tcttcttcag aagttgattc
     4561 tttagctacc catccagcct gatcaatatg tagaaattct cttccttcta caaacatggt
     4621 cttgtcgatt gatacttgcg aataagctga taaggatgat ttcacttctt ttaaatcata
     4681 aggactattg tacagtttaa agtcagattc taaccatact ttttttattg ttggagttac
     4741 ctctgattga tcatataaaa atcgtttgtc cgcagctata aattgatgat ttgatagctt
     4801 aaatactgga attccttgtt tatttaagcg ccactcggtt atttgaaaac ttgttttggg
     4861 agtcaatttc ccagattcca ctactaaatc ttcattcgca taaacaggaa cctctccata
     4921 aaccatggga gaacttaatt tttctctaaa ataaatacca aagtcagatt gtgaaaggta
     4981 ataaatttct ttcgaagtat agacgacttc tttttctgtg ctaacgactt ttgaaatggt
     5041 caaaaaactt ggtaacaaca aaataattaa gaatttacgc attcttcctt tccttttctt
     5101 cttgtaaacg caataattga tttttatcag ccaattcttc cagcttttca tctgacaaac
     5161 tcaaaaattg ctctattacg tctaataaat tttccatttt atcacctttg aagcaagtca
     5221 ggaatcgtat aaactttttc cctcgactta gaataatagt acttcgctcg tgtatattta
     5281 gcagcataat cttcatcttt caacttggta gcaaatgctg tctccttatc cttttcatca
     5341 ctcaaagttt gatactgagt ttgcaagtct gctaattgct gacgtctttg gagtaattgc
     5401 tgataactct gcgctaaatt aaaagttggc aagataaata atagcataat caaaatcaat
     5461 acccctccca taaaacgatt ccgtttttgt cgttctttca tcaggtagcg acgacgttgg
     5521 tattcatttt gaataaaaga attattcaat tgtacaatat ttttagacat tttcttctac
     5581 ccgtgtttca ctgataattt catacattcc tgctgcatct tctttttttg tactatcttt
     5641 catctctagt acttttacaa gcagcaactt attgccaaag cgaatttcaa cttggtcatt
     5701 aactttcaag tccgttgaac ttttggccaa gattccatta accttgattc tacctttatc
     5761 tgctacttcc tttgcgactg tacgacgctt gataattcgc gatactttta aatatttatc
     5821 taatctcatc cttattacct caatttatta ttgtaccatt tttatctatt tttatctatt
     5881 ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc tctaataaac
     5941 tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt tggacatcaa
     6001 atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc gttacggata
     6061 aagctttaaa ataatcttga gctaaaaaca atcgttgagt gactttttca aattgaattg
     6121 taattttatt atcttttctt ttattatctt ttctttccac acgttgaaca aagaccttgt
     6181 ccaagtatga tttaaccaaa ccaatctcta aaagataggc tactacatct gggtattctc
     6241 caaaacggtc tatcaactcc tcttgtaact cttcataatt gacacggttg tcaatttgac
     6301 gaattttctt gtaaatttca atcttatgtc gttgatcaga aatataagta tcaggaagat
     6361 aggcatcaat ttgcaaaatc aactcagcat tccctttggt tcttgtgtta gcgttagcat
     6421 taccgtttcg tttagcaata gcttcctcta ataactgcga atacaattca aaaccaacag
     6481 aatcaatgaa accagactgg gattttccta aaagatttcc tgctccacga atcgaaagat
     6541 ctcgcattgc aatcttaaag ccagagccca attctgtaaa tcctttaatc gcttctaatc
     6601 tcttttcaga gacttcactg attgattttt ctggacgata catgagataa gcataagcaa
     6661 tacgattact acgaccgact cttcctctta actgatataa ggttgacaag cccatatggt
     6721 ccgcattttc aataaataaa gtattagcat ttggaatgtc cacccctgtc tcaataatag
     6781 tagtcgtcac caagatatcg tattgtccct caataaagtc taatagagta ttttccaact
     6841 ggacttcact cattcgacca tgaacatatc caatcgaagc ctccggaatc aactcctgta
     6901 attctgaaac cttctgaaca attgtgtcaa ctttgttgta aagataataa acttgacctc
     6961 cacgctccat ttcacgcaag acagcatcac gaatgacact atcattcttt tccaaaacat
     7021 aggtctgaac aggatagcga ttagtcggcg gagtttcaat aacagataaa tctctgattc
     7081 ccagcataga catatggagg gtacgaggga ttggcgtagc ggtcaaggtt aggacatcca
     7141 cttgtttctt cagttctttc aaagtttcct tatgcttgac accaaatcgc tgttcctcat
     7201 caataatcat caagcccaaa tcagcaaaca caacatcttt tgacaaaaca cgatgtgttc
     7261 caatcaaaat atcgacttga ccgtttttca atttttcaag tgttgcagtc tgctcttttt
     7321 tacttctaaa gcgactcaac acatcaatat taactgcaaa attttggaat cgttccttaa
     7381 aattcgtata gtgctgttgc gctaaaaccg tcgtcggaac tagaatgaca acctgtttgt
     7441 gatcattgac tgctttaaag gctgcacgca tagcaacttc agtctttcca aaaccaacat
     7501 ccccaactaa aagtcgatcc attggctgag aagcctgcat atccctcttg atttcctcaa
     7561 tactacgaag ttgatcatcc gtttcaacat aagggaaagc atcatcaaag gcatcttgat
     7621 catcatcatc agctgagaaa gcaaaaccct tcaactgact acgttcagag tagagtttga
     7681 ttaaatcatc agctatatcc tctacctggt tcttaacctt ttgcttggcc tttttaaaat
     7741 gaccgtcatt taatttattg agttttggag ctttaccatc acttgaaata tatttggaca
     7801 gtagatgaat ctgttccacg gggatagaaa tttgatcacc attttggtat tggacactga
     7861 cataatcgcg atgaattccc ttgatttcaa tggtttcaat tcctagatat tgaccaatcc
     7921 catggatatg atggacaaca tagtcccctt tttcaagttc attgtaatct tttaatctct
     7981 ctgcatttga aacatgttgt cttcgaaaac gacgctttaa tttcttttga aaaatctcat
     8041 gttcagttat caataaaatc ttttcatcta caaaatgaaa accatgtctg agattaccct
     8101 ctattaagtt tacagattct ttacagatac ttgtcttatc tctagaatcc aatttaatct
     8161 gatattcctc taacatatcc tccaatgttt tacttcccat tgaattgcta gactgcagaa
     8221 taatggtgta atccattttt ttatatcgtt caatttcttc ttttagaaaa gaaaactgat
     8281 tgaaaaattc ctgcatagga tattgattga attgataaat tttgtcaaat ttgagatttc
     8341 ctaaaccctt ttgaagatta gagaaaaagg tcactggact ttgtttttta tagatttgtt
     8401 caatatcaga aaaatactgc atatcagaaa atgctttact attctgtaat tcttctgtaa
     8461 agtactgcgc taattctctt tcaaagactt catactgatt catcaatttt tgataatcat
     8521 caaagaatat tggagtatct ttttcaatat aatcaaagac agtccatgtc ttatcatagc
     8581 acaaagataa aaacttccga gagtctgcat gactttgttt ttggtgaaaa cttgaaagaa
     8641 tttcttctag gtatgatttc aaaataggtg ataaagtttt tgaaatttgt ttttctaaag
     8701 ctgactgtcc tcgttgataa tccttttctc tcaaaagcat atcactagct ggaaagatag
     8761 tgagttctgt cttattttct ttcgataatt gtgtttctac ttcaaatgac ctgataccat
     8821 caatttcatc accaaaaaac tcaattcgac aaggttctaa ctgggatatt tcaaaaatat
     8881 ctaaaatatc tcctcgaaga ctaaattcgc cctgagtttg tacttgagta acttttcgat
     8941 agccattttc ctttaactga tggataaacg cgtgttgatc atattcttca ccaactgaga
     9001 tttttacaat actatctttg aatgcattgg gagacggtaa aatcaatcga cttgctgcga
     9061 tattacaaac taaaatccct ttcttagatg aatcagtcaa aaaacgcaag gcttcaaccc
     9121 gtgaaataat tttttcctgt gaagacatca aaaactccac cataggagca tcatctacca
     9181 aaaatggata gacgagttcc tcacccaaga tagatataag atcactaaca agtccttctg
     9241 cttctccata agttgacgtc aataacacaa tcctatcttc tttttctaaa ctgcttgcaa
     9301 ttgcaagagc cttagtagat gttgataaac caagtattag ttgtcttttc ttatctgtta
     9361 aattttgatg ccatttttta atctgatcat tttctgagag taaatctaat aaggtcacca
     9421 tttatccgtt atacctctgc attgttttct caaaattttt ctcttgtaaa tagtagttta
     9481 cagaatcgtc aactttgtca acagactgta aaataccgat ataatcatcc ctgtcaaact
     9541 tactcaaaac atgatgaaca actgacatac catttttagg tcttccaatt ccaatcttaa
     9601 cacggttaaa gacctgagtt cctatatgtt gaataataga cttgatacca ttatgaccac
     9661 ctgctgagcc ttttgctctt aaacgaattt tcccaacttc catgtcaaga tcatcgtaaa
     9721 tgataagtaa atcgtcaata tccaaaccat agtaagttaa taaagcatga actgcttttc
     9781 cactttcatt cataaaggtc gttggtttaa ccagataaat tttttctcca tttaggaaaa
     9841 aggatgctag gtcagcttga aatatcttat cgtgtgtaaa agtgacattc tgtttcttcg
     9901 ctagttgatc aatcaacata aaaccaacat tgtgttttgt ttcaaaatat ttatcccctg
     9961 gatttcccaa acctacaagt aatttggtca tttatttttc ctttcaaaag ccaaaagggt
    10021 tggaattttt ttccaaccta attgacacca tttattaatt tttagacatt aaagcggaat
    10081 tccatgatat cgccatcttg aacgatatat tcttttcctt cttcacgcaa gcgtccagct
    10141 tcttttacgg ccttttcaga tccgtatttc actagatctt catatgacat ggttactgca
    10201 cgaataaagc ctttttcaaa gtctgagtgg ataataccag ctgcttgagg agccttcata
    10261 ccacgtttga aagtccaagc gcgaacttct ttttcaccag ctgtgaagta agttcccaat
    10321 ccaagcaagt ggtaagctgc acgcgtcaac ttatctacac ctgattctgt caaaccaatg
    10381 gcttcaagaa actctttttt atcttcatca tccaattcag aaatttcttc ctcagcacgc
    10441 gcagaaataa cgactacttc agcattttct gtcgctgcaa attcacgaat ttgtttgaca
    10501 tagtcgatag agtcaggttc tgaaaccaca tcctcgtcca cattagctac ataaagaact
    10561 ggtttagtcg tcaaaaggaa aagacctttg acaacctttt gttcctcatc tgtaaattca
    10621 atggtacgag ctgatttccc gtcttctagg actggtttaa tcttttgaag aacattgaat
    10681 tctgctactg attctttatc tttttgcgta cgtgccatct tttctacacg cgcatatcgt
    10741 ttgttcactg attctaagtc agcaagaatt aattccagat taattgtatc aatatctgca
    10801 agtggatcta caaaggcgtc ttcacgtcct tgctcgcgca ttacattttc atcatcaaaa
    10861 gcacgaacta cgtgaacaat cgcatctact tcacgaatat tggccaagaa tttattccct
    10921 agcccttctc cttttgaagc tccttttaca atccctgcaa tatctgtaaa ttcaaatgtt
    10981 gtgggaactg tctttttagg agttatcatt tcagttagtt tttgtaggcg ttcatctgga
    11041 acttccacca ttccaacatt tggatcaata gtcgcaaatg ggtagtttgc tgcctctgct
    11101 cctgcttttg taattgcatt aaatagtgtt gatttaccaa cgtttggcaa accaacgata
    11161 cctgctgtca aagccatatt tctcattctc cgttttcatt tcaatcccta atattataac
    11221 acaaaaaggg aaaacttgct aaaattcctt gatatagcta tttcccataa ctgaaataat
    11281 aattttatgg acttttttag gaacttttta atttttcaat agctttttca taaaatgaag
    11341 tagcattttt ctgattgtct ttggataggt ggctataaat atccatggtc atagaaagtt
    11401 ttgcatgacc gagccgtatt tgtatctctt tgtaaggtag tccagcattg agcaagatac
    11461 tagcatgagt gtggcggaag gcgtggaacg taaaacgagg gcatccagca cgttccaaat
    11521 gttttactaa cctgaaacta agcattctag cgtctatatg cttatcaaag ctattagaga
    11581 atactttctc ataggtcaac cccatttctt tccctatttg ggattgtctt gctttataga
    11641 gccgtagcat gagcaccgtc ttattatcca agtcaattac cctaatactt gatttagtct
    11701 tagggccagt gatttctttg ataatattta acgttttatt tacgtctagt gtgccgtttt
    11761 ttaggtcaat atcagaccat ttgagggcta aacactcacg aatacgcaaa ccagtcgcta
    11821 aaagcgtctt atatagcacc gtatcgtaga aatttttgta agtgtttggc agctgctcca
    11881 ggtaagtcaa gaattttttt aagttatcat catccagata tttcagtttt tgcccttctt
    11941 tttccttacg acgtggcacg ataacatcac gggcagggtt aaaggggata gcttgcaaag
    12001 atacggcata tttaagtatg cgtttgttta gagagtgaag gagcggatat tcttggaatc
    12061 ctttgcctag ttgattatag tcttttgccc attgattgac ttgcttttga atgattgggg
    12121 gcgtcagttt atccagccta taatttccga aagctggaag tagatattta tctattttga
    12181 atttggtacc cattaaggtc gattttttaa ccgtatggca gtacgtttct agccaattct
    12241 ccaccagttc ggcgtaagtc tttatctcca ccgctttata tactgtagcc cctccttttt
    12301 caaagtcgat ttgagcctgt agcgctttgg ctttgagttc tctcttggtt cgccctgata
    12361 tagtcgtctt gactttctta cctgttacgg tatcgatacc aaggtagacg ctagagcgat
    12421 agactgtaga cccgtctttt ttggtgtatt ctgttatttt catgatgata aacctttcta
    12481 aaatacatca gcaggcaagc tattattaaa aaggttttag attatggttt atatcatgtt
    12541 gagcttacgg gaaagatttt atttgttatt ttcttcagct aaagctatct gtacaagttt
    12601 ttcttttact ttttcagtga gttcctcata gtagagaatt gaagaaataa tttcttttaa
    12661 aaaattgaaa tcgattaacc ccattgctac ccataagaca atattttcca ttgtttcgat
    12721 aaagaaggga atgaggtaat caaggtgatt gattgttaaa aatttaatac cgaagacaat
    12781 gctacttctc ttatttccat cattgaacat atgaaattga actgtattaa atactagcac
    12841 tgtaagtttt gtttcaaagt ctggatagta atcgtcattc tgtaagtgtt caaatacact
    12901 aaataccctt cccttatctt taacaccgtg taaaccacct attttctcaa ttacttcaat
    12961 gtcgtgtagt aaaattgctt cttcagcaga aaaataattg attttatcca ttatttatct
    13021 ctcaatcttt caaaaacttg gcggtgttca tcaatttgtt ccgaaagtga tttactttgt
    13081 tcgccaataa atctttcaaa atcttcttca gaaattggac ggatatattc tgctaatttc
    13141 tcatgtttgg cattcctgaa agatagatcc ctactagcca ttttctctct ggcatgcatt
    13201 aaatggggtt cttgcattgg gtgatttgct aatctctgaa ttatctcgat tacatcagta
    13261 ttagttagtt tttgatttga agacttactc ttttgttcaa tctcataagc aacccctttc
    13321 tcaaaactag caataactat aagtacctca ctatacattg ttgcgcgagc attatcattt
    13381 ttattcaatt tcagtatttt tttatattct gatgctcttt ctttaaagat tgctttgtaa
    13441 atttcattcg ttaattgacc atatttaaaa ttacttccag agacatactt atcaatggca
    13501 tttgtaaata tttttctagc attatcttct tctaatgcag tcgatagata atttttgtca
    13561 cgctggttta taaattttac atggccacca gtcttctcag ttaacacatt aatgacaata
    13621 tcaagtaggg tatttcttac ttgcttagct atatcactat tggttaacaa catagcaaaa
    13681 ttaagcaatg ttctgaacga tgagatactt aattgtgtaa ctttgctacc gacatttgtg
    13741 tcggtagcaa aagcattttc tttaaattta gctagttttt ctccacgtaa agtgtgataa
    13801 ccattttcag taagctccgt tttatgagct tcaacaagtc tttcaatagt tcgaatgtcg
    13861 acttcgaaaa aggtagctag ctgagaattt gtaaaataaa aagtatcctc aaagtagaaa
    13921 ccaggtactt ttaaaatctc ttcagctttt tgtaatgcta aagaattatt taaaatattt
    13981 tgtctttcta tttgtgaggt tgtcagatca gtcataattt ctcctttttg tcgagttaat
    14041 ttgccaataa ctcccgatat ttcaagagtt ttattttatt ttcgtgtcgt tagagtatat
    14101 tagaaaatct tgaactccgc gaatacacgc gcttcaggat tgttgaacat tgtggcgcgt
    14161 gggttagtcg ctgaagtgtt ccctgatttc ttcagctaaa tcattcaagc ggttctgaat
    14221 acctttatag taatcaaatt caatggtgtc aatgatgtca cttttttcag taaatatctt
    14281 gttttttgta acacaaaagc tattatttgt attattgtga acaaggtcat ttatctcatt
    14341 ttgaacagaa gatattttcc tttgtaagca atagcctaag atttttcgat cttgaatacc
    14401 tattttttca attatttcat tcacttcaaa gacaactgcc ccatagctat caattttatt
    14461 gttaaggcta ttgataagat tagaaatttc agaatgcaca taggaggtat tgagagcttg
    14521 ctcacgttca ataacgttta ttaaacgtgt aatatattcg ttagtaatca tggtgagtac
    14581 attattataa gcgtactccc tagcttcgcg ctgtttggaa agtagtagag cctcattatt
    14641 ttttgagata tctgataaat caagtccgtt gaaaatttca acaataccag ggtttattat
    14701 tgaagactga agaacgcgac ccaaaacacc ctggtcaaat gctatttttc ctcgaatgta
    14761 ctccatattc atataatctt ttttaaagct aagtatttct ttgattttat tgaagaacat
    14821 ctcaaaaacc ttttctcttt gattattatc tagcaactct tttagtgtgc tggttgaaac
    14881 tgtatcaata aaccgcagat ctaggaaaga tttttttacg ttcaaaaaat cagctatttt
    14941 ttgtaaattc ccagcggttg gtaaagattt tccttttaca tatcccgtaa ttgtactttt
    15001 aggaatatct aaagcgttat gaaggtcaat ttgtctaacc cctttttgtt ccataagaag
    15061 gttgagccgt ttagagaagt attctctatt ttcaagatct tgaggactat ttttagccat
    15121 gactttaacc ctttcagttg taagttatac attgattata acacaaaata aaaacaaagt
    15181 acgaaaataa ataaactttt ttctaaaaac acttgactag gtacgaaaat aatagtacta
    15241 ttaacttatc acttttgaaa ggaattgtta gattatatgg aacaatggac gttgaaagcc
    15301 tgtagagtaa acgctggtta tactttgcga caggttgcta aaaaggtaaa taagaatttt
    15361 caaactgtct ccaagtacga aaaagatagt acatatatac cgtttgaact tttaaaagaa
    15421 ttgtctgcaa tttaccaagt taaattggac aatatttttt taggagatag tacgaaaaaa
    15481 atagaactaa ataaaagaga gttgcaataa tgagagtatt attttaagtc aatggtggca
    15541 gaaatcaaac cagacataac aatagatgaa ttattttata gctagaaagg agcaaaccaa
    15601 tggaactagt ctatatggac ggtaaaaaag agccgtatac actgagcagt attgtggcag
    15661 agtgtgcaga agtcaagcac agacatttga agattttgct aaataaacac cgagaggact
    15721 tcgagagttt cggaaaggtg caatttaaaa tttcaccttc agaaagtggg caaaatgtac
    15781 gggactatat tttaaatgaa caacaagcaa cattgctgat cacttactta cgaaatacag
    15841 aacccgtaaa agagtttaag aagaacctag tcaaagcatt ctttgaaatg cgtgaggaac
    15901 tttctaagtt tcgtatgcag agggcgctag aaaagccaaa aagaaaaacc ttgcatgaca
    15961 gtattaaaac atgggaggca aaacccaagc acgcgcatag caccatgaac aacctgttac
    16021 tgaaggcagt aactgacatg aacgctaagc agttagtaaa aagccgtggg ggctataatg
    16081 gcattgatag cttgaccagt gacgagctgg agcaatacca ggcatttgag gatatggtaa
    16141 tagccatgat tggcttgaat atgagttatc aggaaatcaa agctatggca ttcagaaata
    16201 aaaaaacacg ccaaagaagc gtgtgagagc aacaaaaaag gcttagcaat aaccacaccg
    16261 cagagccttt cacactaaca ctaaaacgaa tttaacaaaa agcaggcaag ctattatcaa
    16321 agaggtttta gtaaagattt atacctagat tatagcatat ttagggcaat ttgaccatac
    16381 ggagagcgcc aactctttaa actggtactt tctcacgctt tcaatttggc gagtctgagc
    16441 gtgaggctag tacttacaag aaaaaactgt ataagaaaca actcaaaaag ccccacgctc
    16501 agaagtttgg cgaccgagag catgaggctg taggcaagaa aaactgtata agaaacaacc
    16561 attcaaaatc cccacactcg ccatcgctca actttgagtg tgaggatcag caggtatagt
    16621 aaaaggtatt aaatggccct tagggcaact acacaacata gaaacagagg taaaaacatg
    16681 acagaaacaa catacgagaa tttaactaga cgtataaaca gaattagcgc agaaatgcaa
    16741 gaaattggcg aaaaaaatgg gcttagtaga ctttcgttat tggcaagtca gacaaaattc
    16801 atcaaagaag aattatcccg tttactttgg attgaactcc ctgaattgaa tgacagccat
    16861 aaaatcgaag cggtctctaa aagcactacg ggaatgtttt tccaccctgg tatttttgaa
    16921 atggacgcta tgcgacaagc attctttaaa cgccaagcta tgcacttttt tgagaacgaa
    16981 gcagagcaac aggcgtatat agaacatgct gaaaaggagt atttagaggc tactataacc
    17041 ttaaaagata ttctttttaa ctctaaaaat ggaactcaga gagtaaataa aagttgtctt
    17101 atagagaagt ttgaggaggc aatgcaatga cactagacct agacaacatg acacaagcag
    17161 aatttgataa acaaatggct gaaatcaagg agagaaatcc aaacattttt caactgattt
    17221 ctgatttttt agatagaaag gtaacacccg aagaggtgga tgagtttttg aagatggagc
    17281 gagctgaaca agtggaatat attaagaatt atcaagcgag ggtataacat gaatgagcta
    17341 gatataagta acacacaggc tgctgtctta atcgtgattt tgattggctt actgctttat
    17401 ttaaaccacc gagaccgcaa aaaaagcgcc caaattgagc gagaaaacca acagacgata
    17461 aaaacaccta gcgaggattt aaaccctgat tatgggcgat atatccagct tgcaggagtc
    17521 aacgtatggg gagggatgga atgagttaca caatgaattt ataccccgat attgaaaaaa
    17581 taccagatga aacctatttt actaaagaga tttttctagc aacgtgcttg aataacacaa
    17641 tcagaatagc agtagccaga ggagtgctaa catctcaact tttagacaaa gaaactaaag
    17701 aagttgtttg taaaaccttg gatacaatca tagaaaatca aaaagctatt ttgcaagggg
    17761 tagcgagcgg acaaataacc tttgtaaata aaagcaaagg agaggagggg ttggatgagt
    17821 ctatcagaga atgacaagcg agttttaaga ctaatcaagg taggggctga gaactccata
    17881 acagggtcag aaattagcct gacaaccaag ctaacagaaa gaactgtacg tgacattatc
    17941 aagcgtctag tagttaagca caacatccct attgtagggg ttagatgtgg cgtttttagt
    18001 gggtacttta ttccagcgaa taaaggcgag ttactagatg gcgctaaggc tttttacaac
    18061 caagtacagg aggagagcaa gcgcctagcg gtgttgatga atagcgacct agaaagctac
    18121 aaagaaacct tgaaggaggt gggcggatat gtttagccta agccgagaaa gcgagcaaga
    18181 cctagcgcat ggcattctgg aggtagtgga aagatacctg gaagcgcgtg agaaagtacc
    18241 gccaagattg accaagttaa taaatagagt tgaactcaaa gaggaattga aaattagtga
    18301 caacacgctg aataagtggg aaagtcaggg tttaagacgc tatcaaccgc cggacgatgg
    18361 tgctagaata atattttatt tagtggatga cattcgtagg tttatggggg tggagaatgg
    18421 gtagatataa cacacaccca gcgcaaggcg gaggtcatta tcatgacatt aaattgtata
    18481 agcaccgtgg cagatctttg gaacagttcc aagaacaaaa gctactgaag aagttaaaaa
    18541 aaaacgcaaa aaggggcgat agtatgacaa tttatgaggc tagaggtttc cagagtaatc
    18601 ttgtctatcc atttgataag atggagccgt tccagtacat tgaacgcttt aagcctttgg
    18661 tagtccctga aagtgctgat ccggaggaat acaaaagaac tcaggcgcca tattgtttaa
    18721 gtggtaaggt tatgccggag aaaaacggga gttacaaacg aaacaactcc agtctaatct
    18781 atcgggattt gattttcctt gattatgacg atatacaggg gacgactgag gacttcatag
    18841 aagccgtttc tagcgctttg tttggctact cttatatctt atacccgact atcaaacata
    18901 gcatagaaaa gccccgtttt cgccttgtgg tgaaatctaa caacgtgatg aacgaggcaa
    18961 cctataagca ggtagtaaaa gagattgctg acaagattgg gctacccttt gacatggcca
    19021 gtttaacctg gtcacaactc caagggctac cagtaacaac aggcgaccca gcaacttatc
    19081 aaaagattgt agagcatgga cttgattatc cagtccccaa ggttgaacca agagcgaagc
    19141 aaggaactac tgagcgttat aaacctagag taagtggcca gaggtcaatg actatgagga
    19201 tcattgacac gcttttcaac ggatttggag acgagggagg gcgtaacgtg gcagtgacac
    19261 gctttgtggg attactcttc aataagtggg ttgattgtga cctagagacc gcctatgaac
    19321 tgacaaagat agccaatagt gtgacagttg aaccattgcc tattgaagag ctagaccgca
    19381 cttttagcag tatagcacgg gctgagtata gaaagagagg ttagaaccat agaactagaa
    19441 gaattagcaa acctaaaaag tgaaatcatg gaggtaatgg agcaagaaca ccctcctaga
    19501 acgatgaagg agcttgaaaa tcgtatcttt aaagctggag aagaatggcg ggcagaacat
    19561 actgaaacta aggtaaatga gaccacaggg gacgttaccg aaaaggttgc catgcctcag
    19621 acattcacag tagcaaaaat actgagcgag attgtcacat ttacttttat cagcaagagc
    19681 aatatacctg attatagcct gctctatatc tatgatttag acgagggtat ctataccgct
    19741 agtaatgatc tattcaatct tttgtgtaag acctttgacg ttagaattaa acccagagag
    19801 tggccacaga ttaagttaat ggttagaaca ttggcaaaga tacgaaaacc tttagagagt
    19861 gctaaccttg tacctgtaaa gaatggcatt attgacctaa gaactaagga gctactcccc
    19921 tttagtccta agtatgtaat tacaagtaag ataagcacgg cctaccacgc gcctaaacga
    19981 gtcccaacag atagagaggg caaaactttt gatgattggc taaactcaat cgcttgtaat
    20041 gatagtgaac tggtaacact gttttggcag attatccttg aagctattaa ccctaaccat
    20101 acccgaaata agtttgctat cttctacggg gacggtaaca atggtaaagg gacattccag
    20161 cgcttcctta tcaatctgat aggggaaagt aatatatcag ccttgaagcc tgcacagttc
    20221 ggagaaaagc ataacttgga gaccttggta ggtaaggttt gtaatattgg ggatgaagcg
    20281 cctaacgaat atttaaaaaa tccgtctgat ttaatgagta tcactagtgg cgacactgtt
    20341 ctagtcaatc caaaaggacg cccagccttt gaagctactt tcaagctatt caatatcttt
    20401 tcagggaatt atattcccaa tggtggcaac aagacaaaag gctggtatcg tagaattatg
    20461 atcgtccctt ttaatgctga ctttaacggg gagaaggaaa aaccttggat taaaaatgag
    20521 tttttagcaa acaaggaagt cctagagtat gccctctaca aagctatcaa tcaagagcca
    20581 tttactcact ttatcgaacc taaagcagtt aaaggactcc tagaagaata ccaggaggat
    20641 aatgactact tactttcatg ggttaagcat gaatacatgg aaaaaggttg gcatgagctg
    20701 gacgtagtac ctgtttttat cgttacaaga tcactaaagc actatgccga agatatggga
    20761 atacccaaac ccaatgttta cggggctggt aaagaaacta tcaagcactt acaacagttg
    20821 acacctaatc ggtattctct aagaaagaaa agagttcctt cagaagattt tgaaaaacta
    20881 gaggcatggg acgttgacaa gataaaaatg cggacacctc aacactctat cactaaacaa
    20941 gaataagtgt gacgttcttt ttttgcttaa acccttgata atactgattt tcttaaaaaa
    21001 agtgtgacgt tctcaaaaaa gaaggttaca ccccttgaag ccttgatata tctagcttta
    21061 ggggaatagg tgtgacgttg tgacattctt tccaactctt atatatagag aaaaatgcag
    21121 tatttatata taggaacgat aaaacaaaag aacgtcacag ggtcacaggg gtggtgaaac
    21181 acctagagcc tcaagggttt gaacgtgtga cgttctttgt cacagaaggt cacagaacac
    21241 gaaaaatatt acataattta ccttaaaata aagaaatgac aacaacatga aagttaaact
    21301 atttgaatat actagacgat gggaaaaaga agactttgag aaagagatca atgacttcat
    21361 ggcaactgtt gaagtgctgg acgttaaatt ttctggtaca ccatctagtg aatcctttaa
    21421 ttcggtggct atcgtattgg tattatacag ataacaaaat ggggtagata gtaccgaccc
    21481 ccttgtaatg gtgtaactac tagtgacacc tttaaaacag aaagaggaaa aacaacatga
    21541 cattaaaaac attttcggat aaagccaaaa catttacttt cacttacgaa tttaaagacc
    21601 tagatactgc tatggtagca ggtcacgcgc tactgggata tatgactggg acttatgaag
    21661 taccatctat ttcaataact cacaaggata aagggacgct tgtcgctgag tatgtggaag
    21721 atcacaagct aaacaagact ttcaagcgta tttgtgacag tttcaaagac tattacaacc
    21781 aaccagtgga cgatgaagca tttgaagaac gttataaacg ggagcgcgtg ctccaactca
    21841 aagagtaaga ggactttgag aacttgctgg aaaaagtaac agactacgag ctggaactat
    21901 tagactatgc tgatcgcttg ctttctgata agcctatccc tatggactct atgaccgctt
    21961 ttggtacgtt ggaaatgctg ggcgatgaaa gtattagcct actccaaaag ttggacgtag
    22021 agggcgaata taaaggcctt gctggttata cagagcattt gaagtagaac acaggggagc
    22081 aatccccttt ttgttatcaa gtcaatagtt ttgggttttt ccatataggg ggaaataatg
    22141 aagcggttag caatagaaac aatcactaaa ccaatgaagc tgagaggaat atctaagggt
    22201 atagctgagt tggacggtca acgtttagag attgatttgg ataatttaat gattgatttt
    22261 ggtggagagt catttgaatt agacagaata gcaggaacta agggaggtaa tagatatttc
    22321 tttgccctga ttgtgggaga cggtgcaggt tgctttataa acggtattta tattttagtt
    22381 gcggtacttg tctagatatc cacaagagca ccctgaaccg tagtaaaacg gattgccaat
    22441 actactggga gcttgcacta aaagaagcca gaaaggtaga accagggtgg agtcctagac
    22501 gtggtggata tatgtttgat agtttccctg aaagaccaaa gtatatgaag cgtgacaggt
    22561 atcataagca ctataagaag tttttgaagt atattgaaaa aggagataga ttttggctga
    22621 atggtttgag attgtaggac aatatgaagt agtgtgcaat ttacaaaaca aacaaatact
    22681 acatatttga cggtttgaat gttaaaaaag ctagatatat caaggattta agtaagtaga
    22741 gtgttccaaa agagggtgag gtaagggtga ggttacatat aaaaagtaca aggttagtac
    22801 aaggtcacat acttcaaaat agcaaggttt tagcaaggta cagggctttt ttctagtgat
    22861 agaaccctaa tattacccta aggtatagct acttttttag aaccatagaa cggtaaggtt
    22921 acggtaaggt atcgaagttt tccaatggtg aggtaagggt gaggtaagag caaaaaatgt
    22981 aaaggttttg tcaaggttgc gtatttaaaa gccccaaggt taccacaagg tagagaggtt
    23041 taccgagggt tagaaaaggt gagattttgc ttaggtagtg gcagtaaata tgcctggaaa
    23101 atggcagggt tatgtgtgtt gaactccgag cgaacgccga gaaagtggct atatctccct
    23161 ccccacgcac ttctatgagc ttcacaccgt cattgtacat tttttctcac ggggaagcat
    23221 ttgaagctag agcgaacata gagaaaacga aaaaagccaa gacactctct gtctcagcta
    23281 atagttctca caaagactat tatatcatag aggaggccga ggcatgacac cagagcaggt
    23341 aaaagaaaaa ctagagggcg ttaagtggat aaacaaagag atagaaggct tatatttaga
    23401 gcttgcagct ttagaaagtg gtattatcaa aaagcaagaa ctaagcaata ccagagtaca
    23461 aacaagcagg gtaaatacga ccgagaataa ccctataagt gttctaaaac taaaagagga
    23521 tacacttcag agaattgagc gacttaatga agagagaatg gaaatatcta ggctaatcga
    23581 taagctagcc aatccgcttg aacgttctgt tctcaggctg ttctacttga atgttcttga
    23641 cgcttggcaa gttgctgagg aaatagataa atcaaagact gcagtataca ttataaggca
    23701 aaaagccata gaacacttag caaatgtggg gtaataggtg agcacaaaaa aacgcctaga
    23761 acaatctaag cgctaaagag tagtggacgg tgtgcctgtc ccgtcatctc atactatgaa
    23821 gttgcgtagc gacactatca tctctacctc acttctcttt agactattat accacaaagg
    23881 agcgaactaa tggagctgga taagtttaaa acgatgatga acgtcagaga gcggatgacc
    23941 tactttctac gtttccagag gatggcagga agtgaaaacc aagttacgat agatgaagag
    24001 gcttggaaac ttgtcttacc ttatcggtgg gatttgagcg gtgagcatga aaaagcaatc
    24061 cgtgaggggt tggaaatatt cgcccaagac atcaacagta tagaaaacaa acgagctaga
    24121 aaatacttta ttatccatta ctgttacatg agaaagaaaa caatgagcga atgcgtagaa
    24181 atggcagcta ctagctccac tagctaccac cgatataaac aaatagccgt cttaaatttt
    24241 gcgagaatcc accagaacgg agagctagaa gtgtataagt aggcgtttgt ggtgttttgt
    24301 tgagaaatgt tgagatttaa gtgagggggg atgacatgat tgaagatttt ttgattgatt
    24361 tggagaatat ccaattagag gatatggaga tagattttaa catggatata gacatcgatt
    24421 taaacataga ttttgaaata gatgttgacc ttgatgattt agatttaacc ttactacaag
    24481 aattagaagc gtaaatgttg gcaaatgtag gctgaggctt catattcgtc ccctattttg
    24541 ctttggtttg gactggacaa ttaaaacacc atggataaac tagaagccct cagaaacgag
    24601 tctaggggct tttgtgaggt cataatctta taaaccacgc gcttcatggt ataatatacc
    24661 tatcagcaac cagcaataaa aaaagcacgt ttaaccgtgc tagtttcttg cctgctgaac
    24721 tcgtcattta ttgccctttt gtggggcttt ttttgtggac tttttgagaa tttttaagaa
    24781 cttttaatga tttctaatca aatgagattt ttcaaaaagt cagtaatatc aagggtttag
    24841 gcgctttaaa caagtttaaa agcgtataga ttacaatcta acacaaaaag ggataaagtg
    24901 ctaaccctct aactaagggt tctcagtcaa taattttatt catttttcgc tcaaaatcat
    24961 atcgccccat catgacaaca tgctcacaat tactgcattt tattttgata tctgctccta
    25021 cacgtgtaat ttcccaacaa ttagcctttt taccagtcga cttgattgta caagcgtgtg
    25081 attttttcat ctcaacaaaa tttccaactt gatacatact actctccttt tctttttcga
    25141 ttatatcata aaagaggcga gccaggctca acctctttca cttaatttgt acgaactggt
    25201 gtaatgagct gcatgaagtc ttcgtcagta tctgctggca caagagtaaa tggacgaaca
    25261 gctgagataa agctaatggt caccttttcg ctatttaaag ctttaagaga atcaatcaag
    25321 taagttgggt tgaaactaat ggtcaaatct tcaccagtaa cctgatcagt atcgatttct
    25381 tcgtttactt taccaacttc tggagagtga acatgggcgc taacaacccc atccttaatt
    25441 tcaagtttca cagtaccatt ttgagtcgca cttgataaaa gacgggcacg ctccattgac
    25501 tggcgtaagt ttaccacatt aaaagtaata gtagtgttaa agtctgttgg aatcaagcga
    25561 tctgtatcag gatagtttcc ttctaggaga cgagtataga agctaatatt ttcgcttcta
    25621 aagaggattt ggttattggc aaagaaaatc tctacagttt cgatatcatc tgtaaatacc
    25681 gctgaaaatt cgcgtagaga acggctagga attacgacat caaaatcatc actatttttt
    25741 tcaagagtca attttttctg gcttaggcga tgagagtctg ttgcaactgt ttttaactct
    25801 ttgtgttgac tcaatacgaa gtggacacct gttaaaatcg gacgactctc ttgtgtactt
    25861 gcagcaaagg ctgtttcatt aataattttc ttgagtaatt ttgtttcaag tattaaagga
    25921 gtgcttgctg aaatttcttg gattcgtgga tattgttcgc tatcttttcc ttttagggta
    25981 atttctgatt tgccactggt taaaacaatt tgattttgtt caatttcttt aaaatcaaga
    26041 gttacatcag gtaaactaga tactacattg ataaagaaag aagcttcaag aaggatcgaa
    26101 cctaaagaag taattaacaa accagcatct tcattttttt gagaaataaa attttcaatt
    26161 gaaatttgac catttgaacc aattaaagta ataccttcat tggtcacgtc aatttttact
    26221 gttgataaaa taggaatggc atttttagaa ctaatagctc tcttagtagt atttaatgct
    26281 tgtagaaata aatttttatt
//
LOCUS       DAVLIK010000026        25975 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLIK010000026 DAVLIK010000000
VERSION     DAVLIK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25975
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.026"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            463..1506
                     /locus_tag="VXE87_001250"
     CDS             463..1506
                     /locus_tag="VXE87_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0842793.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1674..3761
                     /gene="topA"
                     /locus_tag="VXE87_001251"
     CDS             1674..3761
                     /gene="topA"
                     /locus_tag="VXE87_001251"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0842794.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3867..4226
                     /locus_tag="VXE87_001252"
     CDS             3867..4226
                     /locus_tag="VXE87_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0842795.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4319..4951
                     /locus_tag="VXE87_001253"
     CDS             4319..4951
                     /locus_tag="VXE87_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0842796.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            4995..5651
                     /locus_tag="VXE87_001254"
     CDS             4995..5651
                     /locus_tag="VXE87_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0842797.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5670..6764
                     /locus_tag="VXE87_001255"
     CDS             5670..6764
                     /locus_tag="VXE87_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV0842798.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGIAVANSLAAVKNGAGRVEETINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLTETINTSEMVSRFPGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYENI
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAITDGIDAQDRVLVTVENRDTETIFNATGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6776..7812
                     /gene="leuB"
                     /locus_tag="VXE87_001256"
                     /pseudo
     CDS             6776..7812
                     /gene="leuB"
                     /locus_tag="VXE87_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            7809..8078
                     /locus_tag="VXE87_001257"
     CDS             7809..8078
                     /locus_tag="VXE87_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0842799.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8082..8441
                     /locus_tag="VXE87_001258"
     CDS             8082..8441
                     /locus_tag="VXE87_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0842800.1"
                     /translation="MAGSSREHAAWALANYGFKVVIAGTFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDHVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8603..9173
                     /locus_tag="VXE87_001259"
                     /pseudo
     CDS             8603..9173
                     /locus_tag="VXE87_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007122522.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            9267..9332
                     /locus_tag="VXE87_001260"
                     /pseudo
     CDS             9267..9332
                     /locus_tag="VXE87_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            9495..11426
                     /locus_tag="VXE87_001261"
     CDS             9495..11426
                     /locus_tag="VXE87_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0842801.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKV
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIGPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            11413..12729
                     /locus_tag="VXE87_001262"
     CDS             11413..12729
                     /locus_tag="VXE87_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0842802.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKEWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12904..13890
                     /gene="guaC"
                     /locus_tag="VXE87_001263"
     CDS             12904..13890
                     /gene="guaC"
                     /locus_tag="VXE87_001263"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0842803.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPTKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13954..14025
                     /locus_tag="VXE87_001264"
     tRNA            13954..14025
                     /locus_tag="VXE87_001264"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13987..13989,aa:Arg,seq:ccg)
     gene            14208..14906
                     /locus_tag="VXE87_001265"
     CDS             14208..14906
                     /locus_tag="VXE87_001265"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0842804.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14897..18436
                     /gene="smc"
                     /locus_tag="VXE87_001266"
     CDS             14897..18436
                     /gene="smc"
                     /locus_tag="VXE87_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0842805.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18433..19227
                     /locus_tag="VXE87_001267"
     CDS             18433..19227
                     /locus_tag="VXE87_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0842806.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYRGQDLYEATMSREFYLTTFEKLKTSPYV
                     DINKLLLTGKKGAYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGIIMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            19227..20045
                     /locus_tag="VXE87_001268"
     CDS             19227..20045
                     /locus_tag="VXE87_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0842807.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            20049..21269
                     /gene="ftsY"
                     /locus_tag="VXE87_001269"
     CDS             20049..21269
                     /gene="ftsY"
                     /locus_tag="VXE87_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0842808.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQAEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(21313..22800)
                     /locus_tag="VXE87_001270"
     CDS             complement(21313..22800)
                     /locus_tag="VXE87_001270"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0842809.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(22949..23689)
                     /locus_tag="VXE87_001271"
     CDS             complement(22949..23689)
                     /locus_tag="VXE87_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0842810.1"
                     /translation="MAKLKIDVNDLHKYYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23689..25854)
                     /locus_tag="VXE87_001272"
     CDS             complement(23689..25854)
                     /locus_tag="VXE87_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0842811.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQSTKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
BASE COUNT         8112 a         4589 c         5736 g         7538 t
ORIGIN      
        1 acactataat ttagtgtaat tgagaaagga gaaatgattg tgattgatgt tggctaggtt
       61 atgttcaatg attcctaccg tctcaaatct tgtcagtaag gaaaaataaa ttcttcaaaa
      121 gtagagatta caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa
      181 tggttattat aagaaatggt ctaaaataga tgatgatact tttcgaaaat ctttttacgt
      241 cagctcagct ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt
      301 tcatttacta gaaatgaaac tgatgagaga tatcagtaga catttgagtc aggatattat
      361 ggaaaatgat aaaaagagct cgtgagattg gcatatcaga ctactaaagt attgagtttg
      421 ttaggatttt agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg
      481 tattcgttga tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat
      541 ttagcgattt tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact
      601 cccgtgatta ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg
      661 ctctctctag ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt
      721 caaattcttg ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat
      781 gctagttcgg agattgttgc tagaacctct ccgactattt gggatgttct cattgctttt
      841 gtaggaggga tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct
      901 ggtgttgcta ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct
      961 tctgctaatc taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt
     1021 attgtcattg cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa
     1081 gataatgaag aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg
     1141 attccgagtt tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt
     1201 aagaaattta tatcagagca gtttcagggg tataatattt tgaaaaaaac ctattctaaa
     1261 aagactcata ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat
     1321 atgatttcaa gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa
     1381 ttgtctgatt cagaacaact tagtaaggaa gagctggtgg agtatttctt ccagtatatc
     1441 aaggataagg aagcaaaaga aaaggagaaa gccaataaat ttgatacaga gtctgaggag
     1501 caataatttc ttgagaatag ctggtttctc tcgtgagtct tctatgtata tcaaaggaag
     1561 actgaggttt taagtataaa acttttcttc tgtttatagt agctaagtct tgacagggtt
     1621 caaaaaatgg tttacacttt ataaagttta ttactttgaa aaggtgtgat actgtggcta
     1681 cggcaacaaa aaagaaaaaa tcaacagtta aaaaaaatct agtcatcgtg gagtcgcctg
     1741 ctaaggccaa gacgattgaa aaatatctag gcagaaacta caaggtatta gccagtgtcg
     1801 ggcatatccg tgatttgaag aaatccagta tgtccgtcga tattgaaaat aattatgaac
     1861 cgcaatatat taatatccga ggaaaaggcc ctcttatcaa tgacttgaaa aaagaagcta
     1921 aaaaagctaa taaagttttt ctcgcgagtg acccggaccg tgaaggagaa gcgatttctt
     1981 ggcatttggc ccatattctc aacttggatg aaaatgatgc caaccgtgtg gtcttcaatg
     2041 aaatcaccaa ggatgcagtc aaaaatgctt ttaaagaacc tcgtaagatc gatatggact
     2101 tggtcgatgc ccaacaagct cgtcggatct tggatcgctt ggtagggtat tcgatttcgc
     2161 ctattttgtg gaagaaggtc aagaagggct tgtcagcagg tcgcgttcag tccattgccc
     2221 ttaaactcat cattgaccgt gaaaatgaaa tcaatgcctt ccagccagaa gaatactgga
     2281 cagttgatgc tgtctttaaa aagggaacca aacaatttca tgcttccttc tatggagtag
     2341 atggtaaaaa gatgaaactg accagcaata acgaagtcaa ggaagtcttg tctcgtctga
     2401 cgagtaaaga cttttcagta gatcaggtgg ataagaaaga gcgtaagcgc aatgctcctt
     2461 taccctatac cacttcatct atgcagatgg atgctgccaa taaaatcaat ttccgtactc
     2521 gaaaaaccat gatggttgcc caacagctct atgaaggaat taatatcggt tctggtgttc
     2581 aaggtttgat tacctatatg cgtaccgatt cgactcgtat cagtcctgta gcgcaaaatg
     2641 aggcggcaag cttcattacg gatcgttttg gtagcaagta ttctaagcac ggtagcaagg
     2701 tcaaaaacgc atcaggtgct caggatgccc atgaggctat tcgtccgtcg agtgtcttta
     2761 atacaccaga aagcatcgct aagtatctgg acaaggatca gctcaagcta tataccctta
     2821 tctggaatcg ttttgtggct agccagatga cagcggccgt ttttgatacc atggctgtta
     2881 aattgtctca aaatggagtt caatttgctg ccaatggtag tcaggttaag tttgatggtt
     2941 atcttgccat ttataatgat tctgacaaga ataaaatgct accagatatg gctgttggag
     3001 atgtggtcaa acaggttaat agcaaaccag agcaacattt cacccaaccg cctgcccgtt
     3061 attctgaagc aacactgatt aaaaccttag aggaaaatgg ggttggacgt ccatcaacct
     3121 atgcgccaac cattgaaacc attcagaaac gttattatgt tcgcctggca gccaaacgtt
     3181 ttgaaccgac agagttggga gaaattgtca ataagctcat cgttgaatat ttcccagata
     3241 tcgtaaacgt gaccttcaca gctgaaatgg aaggtaaact ggatgatgtc gaagttggaa
     3301 aagagcagtg gcgacgggtc attgatgcct tttacaaacc attctctaaa gaagttgcca
     3361 aggctgaaga agaaatggaa aaaatccaga ttaaggatga accagctgga tttgactgtg
     3421 aagtgtgtgg cagtccaatg gtcattaaac ttggtcgttt tggtaaattc tacgcttgta
     3481 gcaatttccc agattgccgt catacccaag caatcgtgaa agagattggt gttgagtgtc
     3541 caagctgtca tcagggacaa attattgagc gaaaaaccaa gcgtaatcgc ctcttctatg
     3601 gttgcaatcg ctatccagaa tgtgaattta cctcttggga caagcctgtt ggtcgtgact
     3661 gtccaaaatg tggcaacttc ctcatggaga aaaaagtccg tggtggtggc aagcaggttg
     3721 tttgtagcaa aggcgactac gaggaagaaa agattaaata agaggagggg cccgaaagta
     3781 aatttcaggc tccttttggt tagaacttga caaaatacat cattttatgc gaaactagaa
     3841 gaagattatt ttaactagga gaagttatgc gtcttatcta tctgataatt ggttttttat
     3901 cactggcctt ggctattgtt ggggttgttt tacccttgtt gccgacaacg cctttccttt
     3961 tgttgtctat tgcttgtttc tccagaagtt ccaagcgttt cgaagactgg ctttatcata
     4021 ctaagctcta tcaaacatat gtagctgatt ttcgcgagac taagtctatt acgcgtgaac
     4081 gaaagaaaaa aatcatcgtc tctatctacg tcttgatggg aatttctatt tattttgcac
     4141 ctcttttacc agtcaaaatc ggtctgggtg ctttgaccat ctttatcact tattatcttt
     4201 tcaaggtcat tccagacaaa gaatagttaa aacagtagtt atttgccttg ataaaattga
     4261 aagcatattc ataataatat gatataataa atttgaagta atattcaagg agaatcaaat
     4321 gatttacgaa ttttgtgctg aaaatgtgac tttacttgaa aaagcgatgc aggctggagc
     4381 tcgtcggatt gaactctgtg ataatctagc agttggtggg acaacaccca gctatggagt
     4441 gactaaggca gcggttgaac tggcagctaa ctacgataca accatcatga ccatgattcg
     4501 gccacgtggt ggtgactttg tctataatga cctagaaatt gctatcatgc tagaagacat
     4561 tcgtttgact gctcaggctg gaagtcaagg ggttgtattt ggaactttaa ctgctgataa
     4621 aaagttggat aagcctaatc tggaaaagtt aattgctgca tcaaaaggaa tggaaattgt
     4681 ctttcacatg gcctttgatg aactaagtga tgaagatcaa ccggaagcta ttgactggct
     4741 cagtcaagcc ggtgtcactc gtatcctaac tcgtgctggt gtgtctggcg actccttaga
     4801 aaaacgtttt gttcactatc acagaatttt ggagtacgct aaaggtaaaa ttgaaattct
     4861 accaggtggg gggattgacc ttgaaaaccg tcaaaccttt atcgaccagg tgggggtaac
     4921 acaattgcat ggtactaagg ttgtttttta aaaaatagaa aggaactgct agctttgggt
     4981 agcagttttc acttatgttt gaaattttta aatcctatca atttaatcaa gaaaaggctc
     5041 atgattatgg ttttatagaa aatagcgaag tctggacata tagttgccag attttgcaag
     5101 gtgactttgt catgactgtg tccatcactg ctgataatgt gaactttcaa gtctttgacc
     5161 aagagactgg tgacctctat cctcacgttc atatggaaag catgagggga agttttgtcg
     5221 gaaatgtccg tgaggcttgt ctggagattc tttaccagat tcggaaggct tgttttgatg
     5281 tgcaagattt tatctgtcat cagactaagc gtatcatgac tcaagttcag gaaaagtatg
     5341 gaaaccagtt ggagtatctg tgggaaaaat cgcctgatac agctgtattg cgccatgaag
     5401 gcaatcaaaa gtggtatgcc gtcttgatga aaatctcttg gaataagctg gaaaagggca
     5461 gagaaggaca agtggaagca gtcaacctca agcatgacca agtagctaat ttgctttcac
     5521 aaaaggggat ttatccagcc ttccatatga gcaagcgcta ctggattagt gtgtcccttg
     5581 atgatacttt atcagatgaa gaagtactgg aattgataga aaaaagttgg aacttaacct
     5641 ctaaaaaatg aaatatttta ataattttca tgaactttca attagctaaa tattctttac
     5701 tgaagaaatt ttcagaaaat ataggattta ccacaccaga ggaatatggt gccatcttca
     5761 aatacctgat tgagaatgtc aagacggatc gtcagatcat ctattcgcct cactgtcatg
     5821 atgacctcgg aatagcagtg gcaaatagcc ttgctgctgt caagaatggt gcaggacgtg
     5881 ttgaagagac tatcaatggt attagggagc gagctggaaa tgctgctttg gaagaaattg
     5941 cagtggctct caatattcgc caagattact accaagtaga aaccagtatt gtcctaactg
     6001 agaccatcaa tacgtcagaa atggtttctc gcttccctgg tattccagtt cctaaaaaca
     6061 aagccgtcgt tggtggcaat accttctccc acgaatctgg tattcaccaa gatggagtcc
     6121 ttaaaaatcc tctcacttat gagaacatca cacctgaatt ggttggtgtt aagattccgc
     6181 ttggaaaatt atctggtcgc catgcttttg ttgagaaact gagagaattg gccctagatt
     6241 ttacagaaga ggatatcaaa ccactctttg ctaagttcaa ggcactggcc gataagaagc
     6301 aagaaatcac agatgcagat attcgagctt tggtagctgg aaccatggtt gaaaatccag
     6361 aaggcttcca ctttgatgat ttacaacttc aaactcatgc agataatgac attgaagcgc
     6421 tcgttagcct agccaatatg gatggtgaga aagtcgaatt taatgcgaca gggcaaggtt
     6481 ccgttgaagc aatctttaac gctatcgata agttctttaa tcaatctgtt cgtttggtgt
     6541 cctacactat cgatgcgata acagatggaa tcgatgccca ggatcgggtt ttggtcactg
     6601 ttgaaaacag agatacagaa accatcttta atgcaacagg gcttgatttt gatgtgttga
     6661 aggcttctgc tattgtctat ataaacgcta atacctttgt tcaaaaagag aatgcaggtg
     6721 agatgggacg cagtgtttct taccacgata tgcctagtgt gtaaaggaga aggctatggc
     6781 aaagaaaata gtagctctag taggagacgg aattggccca gaaatcatgg aggctggttt
     6841 agaagttctg gaggctctag ctgaaaaaca ggttttgact atgagattga cagacgaccg
     6901 ttcggaggtg cagatattga tgcagcagga cctcccttac ctgatgaaac ccttaaggca
     6961 agtagggaag cagatgctat cctactagca gctatcggta gtcctcagta tgatggagca
     7021 gcggttcgcc ctgaacaagg cctgatggct ctccgtaagg aactcaatct ttacgctaat
     7081 attcgtcctg taaaaatctt tgacagtctc aagtatttgt caccacttaa accggaacga
     7141 atttctggtg tagactttgt cgtggtgcgt gaattgacag gcgagattta ctttggagat
     7201 catattcttg aagagcgcaa agcgcgtgat atcaacgact atagctatga ggaagtggag
     7261 cggattattc gcaaagcctt tggaattgca agaaatcgca gaaaaatcgt tactagtatc
     7321 gataagcaaa atgttctagc gacctcaaaa ctctggcgga aagtagctga ggaagtcgca
     7381 caggatttcc cagatgtaac cttggaacac cagctggtag actcagctgc tatgcttatg
     7441 attaccaatc ctgctaagtt tgatgttatt gtaacggaga atctttttgg agatatttta
     7501 tctgatgaat caagcgtctt atctggtaca cttggggtta tgccatcagc cagtcattct
     7561 gaaaatggac caagtctcta tgaacctatt cacggttcag cacctgatat tgcaggtcaa
     7621 ggaattgcca atcctatttc catgatttta tcagtttcca tgatgttgag agatagtttc
     7681 ggacgttatg aggatgcaga gcgtatcaaa cgtgctgttg agacaagtct ggcggcagga
     7741 attttaacga gagatatagg aggtcaggct tcaacaaagg aaatgacgga agctattatt
     7801 gcaaggttat gaagttagac gaaaaaatta ctctagtcct tttgatttgg aatgtcatca
     7861 ttttcttgat ttatggcatt gacaaattca aggcaagaag aagagcttgg cgcatccaag
     7921 agaaaatctt actcatttta gcccttactt gtggtggttt tggggcctgg ttagctggaa
     7981 tcacttttca ccacaagact cgaaaatggt actttaaaac agtttggttt cttgggatgg
     8041 tgaccacact agtagcctta tattttattt ggaggtaatg gatggcaggg tcttcgaggg
     8101 aacacgctgc ttgggctcta gcgaactatg gttttaaggt cgtgattgca ggaactttcg
     8161 gtgacattca ttacaataat gaactcaata atggcctgtt gccaatcgtt cagcctagag
     8221 aggttagaga gaaattagcc cagctaaaac caaccgacca tgtaactgtg gacttggaac
     8281 aacaaaaaat catctcacca gttgaagaat tcaccttcga gatagatagc gagtggaaac
     8341 ataaactcct aaatagtttg gatgatatcg gtattacctt gcagtatgaa gagttgattg
     8401 ctgcttatga aaaacaacga ccagcctact ggcaggatta gaaaaaatag aaaaggaaat
     8461 atagtaaact gaaataagat gtaaacaaat gaattggagc ttaacatcca tttccagcaa
     8521 ttttttagaa actacagtgg actattctgg attcaacaca ttataaaatt atgacaaaac
     8581 acattcacaa gaaggctacg acattttaaa aggtgagggc ggatgtatcg cttgccctac
     8641 taaagttggt tacattatca tgaccagcaa caaggcagaa cttgagcgta agttcgcagc
     8701 caaagaacgt aagcgtaaca aaccaggtgt tgttctctgc ggtagcatgg atgaacttcg
     8761 cgctttagcg caactcaacc cagaaattga agcattctac taaaaacatt gggatgaaga
     8821 tattcttctt ggttgtatcc ttccttggaa accagaagcc tctgaaaaac tcaaagcata
     8881 cggggatggc cgtgaagaac ttatgactga tgtacgtggt actagctgtt ttgttatcaa
     8941 gtttggaaaa gcaggtgaac aattggctgc caagctttgg gaagaaggta aaatggtcta
     9001 cgcctcatct gcttcaatga caaaacgatt gaaactcgct atgagagcaa ggtgtaatgg
     9061 tgtctatggt cgataaggat ggcaaactca tcccagaaca aggaggagca cgttcaacct
     9121 caccagcacc agttgtgatc cgtaaagggc ttgacattga tatagtaaaa tgaagtaaga
     9181 gcaggacaaa ttaatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt
     9241 gtactattct agtttcaatc cactataaaa tcatgatgca cctgtcagat acttttaact
     9301 catgggacta ccgtcaggtt gagtattatt aggatagaga agaagtctag tgttaaggac
     9361 attacagctc ataatactag gcttttttat agaaattctt ttctttttct ataggatatg
     9421 gtattctatg tagaaaatat atgttaataa gtaatgccaa tatttaaaca tcattagtaa
     9481 aaggagttag attgatgaat aaaagaaaag ttagtttaga agatttttat aaatggtata
     9541 gtctaaataa agaagagtta ttaaataagg caactgttgg tgaaaagttt aatgataaat
     9601 taaaagaaga gtttctccag gaatggcctt tggataggat tttaacaatg tcaatcgatg
     9661 aatatgtaat aggaaaggga cagcaaaata agtctttatg ctacgctctt gagaagggaa
     9721 aatacaaaaa tctatttctt ggaatttctg gtggctcagc ttcaaaattt ggtatttatt
     9781 ggaataaaaa aacaaacaaa tataaagatc aagctaataa tgagatttca gagttggatc
     9841 agcgattttc aaaattaaaa tcagatttgt atgaaattat caaagaaggt attcgtttta
     9901 actttgaaaa tcctattttt gatatgaaaa gatcaacaaa tgaatttatt ggtcgttctg
     9961 ctatggtgac aaaattactt tgtatctatt ctgagggaga tcctttcttt ggtgtaaata
    10021 ttaatagtca gaaagaattt tggaaccact ttgtttctca gacaaatcaa ggtggacctt
    10081 atctgcaaaa tcataaaata attgaactgg tgtccaaaac ttatcctgag ttggagccat
    10141 cgaaagtagg aactatgctt tttgagtatt ctaagctttt tatggaaaat aaggaagaca
    10201 atagtacaat ggattcatca aacaattttc gtcatcaatt aactcaatct ctattaaagt
    10261 ctccaaacct tatccttcgt ggtgctcctg gcacaggaaa gacttatctt gctaaagaaa
    10321 ttgccaaaga attaacggat ggcaacgaag accaaatcgg atttgtacaa tttcacccat
    10381 catatgatta tacggatttt gtagaaggtt taagaccagt atcaaatggg gatggagcta
    10441 ttgagtttag gctacaggac ggtattttta aagatttttg tcagaaagca aaagaaaccc
    10501 aattgattgg aggacaagat aattttgatg aggcttggga ttcttactta gaatatataa
    10561 atgttgctga agaaaaagaa tatataacaa aaacatctta cttatctgtt aatagtagac
    10621 aaaatttgtc agtaaattat gatagtggtg ttccaggatg gtcactacct agcaaatatg
    10681 tttacgagtt gtataaagat aaaaattata ataagcaaga atactacaaa agtggtggaa
    10741 aaactgtcct agaaacattg agaaagagat ttggtttgaa agactatgtt tccccaacag
    10801 aaattgatac tgataagaaa ttcgtcttca tcatcgatga aatcaatcgt ggggagattt
    10861 ctaagatttt tggcgaactc tttttctcta tcggccctgg ctatcgtggt gaaaaaggaa
    10921 gtgtttctac ccaatatgca aatctacacg aaactgatga aaagttctat atccccgaaa
    10981 atgtttacat catcggaact atgaatgata ttgatcgttc agtggatacc tttgattttg
    11041 ctatgcgtcg tcgttttcgt tttgttgaag ttactgccga gggtcaagtt ggcatgttgg
    11101 ataaagagct gaatatccat gcagaagaag caaaaattcg tctaagaaac ttgaacgctg
    11161 ctatcgaaaa tgttcaggaa ttaaacagtc attatcatat tggaccaagt tattttctta
    11221 agttgaagga tgtagatttt gactatgaat tactctggtc tgattatatt aagcctctcc
    11281 tagaagacta cttgcgaggt tcttatgatg aggttgaaac tttggaaact ttgaaaaaag
    11341 catttgaact gacaaataat gagcaaaaag atcaggcagt agctgatgac aatgaaggtg
    11401 atgaaaacga tgatgcggat tactgataat caacacaaga ttattaaaga aaaatttgtt
    11461 gaagaatatc ctaaactaag caatcttctt ttagacagaa ccttggaaag tttatcccaa
    11521 gatgaacgta ttttcatttt tccaaatgat ttgactcata ctcctgattt ggataaggac
    11581 caaaagattt ttgaaacagt caatcagaaa atcaagacag ggaacgtgat tggttttctt
    11641 ggatatggtc aggaaagatt aacgatttcc tcacgatttt ctgatgagag taatgaccat
    11701 tttttgcatt atctcttaaa caaggttctt catatcaatc tcactagttt agatgttgct
    11761 ttgtctcgtg aagagaggct ttatcaactt ttggtgtatc tctttcccaa gtatctacaa
    11821 gctgctattc gaaaaggtct ttataaggaa tatcatcgat tttctcataa cgacagtaat
    11881 gttaagggag tgattgatgt aagaagccat ctcaagaaaa atcttccttt cacgggaaat
    11941 attgcctacg caacgagaga gttcacctat gataatcccc tcatgcagtt ggtccgtcac
    12001 actattgaat acattaagaa tcagaaaagc attggtcaag gggtactaga taatctctca
    12061 actagtcgtg aaaacgtatc tgaaatcgtg cgtgtaacgc cctcttataa actagctgat
    12121 cgtgctaaga ttattcgggg aaatcaatct aaacctatac gtcatgcata ctttcacgag
    12181 tacagaaact tacaagaact ttgtctgatg atcctaaacc aagaaaagca cggtttaggg
    12241 tatcaagatc aaaaaatcta tggtattctc tttgatgttg cctggctttg ggaagagtat
    12301 gtttacacct tgttgccaaa aggttttgta catcccagaa ataaggataa gacggatgga
    12361 atttcagtat tttctgttgg gaaacgaaaa gtatatccag atttttatga cagagaacga
    12421 aagattgttc tagatgcaaa atataaaaaa ctggaattga ctgaaaaagg aatcaaccgt
    12481 gaggacttat tccagctgat ttcctattct tatattttaa aagctgagaa ggctggactg
    12541 atttttccta gtatggagca gtcagtaaat agtgaaatag gaaaagtagc tggctatgga
    12601 gctcaattga aggagtggtc tattcgaatc cctcagaatg cctcattcta tagtacattt
    12661 tgtaaaatga tggaaaattc agaagaaaat tttaaagcga ttattgatga agaagtgggg
    12721 agaaaataat ttcccctctt tcttttattt ttaacacaag taaaacccga acgatatatt
    12781 ttaattcata aaataatttg acaaaaactg tactttggtt tataataaat taaggaaacg
    12841 tcggaaaagg cgtagtgatg caagagcata ggtaggtcat tacaaaagaa acgagacatc
    12901 gatatgttaa atgaatttcc aatttttgat tacgaagata ttcaattgat tccaaataaa
    12961 tgtgtcatta aaagccgtgc agaagcggat acaagtgtca ctttaggaaa tcacaccttt
    13021 aaactacctg ttgtgccagc gaatatgcag acgattttgg atgaaaatgt agcagagcaa
    13081 ctggctaaag gtggttactt ctacattatg caccgttttg atgaggcagg acgcattcct
    13141 tttattaaac gaatgcacaa tcaagggctc attgcttcca tatctgtcgg tgttaaggac
    13201 tatgagtatg atttcgttag acagctcaag actgatgctc ctgagtatat cactattgat
    13261 attgctcatg gtcatgcgga tagcgtgatt tctatgattc aacacatcaa gaaagaattg
    13321 ccagatacct ttgtcattgc tggaaatgtg ggaacaccag aagctgtgcg tgaattggaa
    13381 aatgctggtg cggatgctac taaggtcgga atcggtcctg gtaaggtttg tatcaccaag
    13441 gttaagactg gttttggtac aggtggttgg cagttggctg ctctacgctg gtgtgccaag
    13501 gctgcgcgta aaccgattat cgctgatgga ggaattcgta ctcacggtga tattgccaag
    13561 tctatccgct tcggtgctag catgatcatg attggttccc tctttgcagg acatattgaa
    13621 agtccaggga aaacgattga agtcgatggt gaacagttca aagaatatta tggttcagcc
    13681 tcacaatatc aaaaaggtgc ttacaaaaat gtggaaggca aacgtatctt gcttcctact
    13741 aaaggtcatc tgcaagacac tttaactgag atggaacaag accttcaaag tgctatttct
    13801 tatgcaggtg gacgtcaggt tgctgacctt aaacacgttg attatgtgat cgtgaaaaac
    13861 tccatctgga atggggatgc ttcccactaa gacggggtct ttgactaaaa aacttgttat
    13921 tagagcaaat ttctgttata ataaaacaag tttccaccct tagtgtaatg gatatcacgt
    13981 aagattccgg ttcttgagat gggggttcga ttccctcagg gtggatgtaa acattctaaa
    14041 aagcctttaa tagggctttt ttctttacac tactctaaat ttgccactaa aactgagaat
    14101 ctctgtctaa agaattccca aatgctttcc agtcccgttt tagagtgact cagggggctt
    14161 tttttgatat aataaaaagg actgttatca gttagaaaga ggttggtatg aaagaattac
    14221 aaactgtact aaagaaccat tttgcaatcg aatttacaga caaaaagtta ctggaaactg
    14281 cctttactca tacgagttat gccaatgagc accgcctctt aaaaatttca cataatgaac
    14341 gcttggaatt tttaggagac gctgttctac agttattgat ttcagaatat ctgtataaaa
    14401 aatatcctaa aaagcctgaa ggtgacctat caaaactccg tgctatgatt gtccgtgagg
    14461 agagtttagc tggttttgcg cgtgattgcc agtttgacca gtttatcaag ttgggtaaag
    14521 gggaagaaaa atctggtggt cgcaatcgtg acaccattct tggtgatgcc tttgaagcct
    14581 ttcttggtgc ccttcttttg gataaggatg tggccaaggt caaggaattt atctatcaag
    14641 tcatgattcc taaggttgaa gcaggcgaat ttgagatgat tacagactat aaaacccatc
    14701 tccaagagtt acttcaggtc aatggtgatg tggctattcg ttatcaggtg atttctgaaa
    14761 cagggcctgc tcacgataag gtctttgatg tagaagttct tgttgaaggt aagagcatcg
    14821 gtcaaggcca aggtcgttct aagaaattag cagagcagga agctgccaaa aatgccgttg
    14881 agaaggggct ggattcatgt atttaaagga aatcgaaatt caggggttca agtcttttgc
    14941 tgataagacc aaggtcgttt ttgaccaagg tgtgacggca gttgttggac ccaatggatc
    15001 tggaaagtcc aatattacag aaagtctgcg ttgggctttg ggggagtcta gtgtcaagag
    15061 tctccgtggg ggcaagatgc cggatgtcat ctttgctgga acagaaagtc gcaaaccgct
    15121 caattatgct tctgtagttg tgactctgga taatcatgac ggatttatca aggatgcagg
    15181 tcaagaaatc agggtggaac gccatatcta tcgtagtgga gatagcgaat acaagattga
    15241 cggcaagaaa gtccgtctgc gtgatattca tgaccttttc ttggatacag gtttgggacg
    15301 agattccttc tctattattt cccaagggaa ggttgaggag atttttaatt ccaagtctga
    15361 ggaacgacga gctatttttg aagaagctgc tggagtttta aaatacaaga ctcgcagaaa
    15421 agaaaccgag agtaaactgc agcaaactca ggataatctg gaccgcttag aggacattat
    15481 ctacgagttg gataatcaaa tcaagcctct tgagaagcaa gctgagaatg cccgtaaatt
    15541 tctagactta gaaggtcaac gcaaggctat ttacttggat gtattggttg ctcaaatcaa
    15601 ggaaaataag gcagaactag agtcgacaga agaagagttg gctcaggttc aagaactctt
    15661 gatgagttat taccaaaagc gtgaaaaatt agaagaagaa aatcaaactc ttaaaaagca
    15721 acgccaagat ttacaggctg aaatggccaa agaccaaggc agtttgatgg acttgactag
    15781 tctgattagt gatttagaaa gaaaattagc cctatcgaaa ctggagtctg agcaagtggc
    15841 cttgaatcaa caggaggcac aagctcgttt ggctgctttg gaggataaga gaaattcact
    15901 cagcaaagaa aagtctgata aagaaagctc tttagctctg ttagagggaa atctagtcca
    15961 aaataatcaa aaactcaatc gtttagaagc tgaattgctg gctttctcag acgatcctga
    16021 tcagatgatt gagctcttac gtgaacgctt tgtagctctt ttacaagaag aagcggatgt
    16081 ctcaaaccag ttgacccgta ttgagaatga gttggaaaat agtcgtcagc tttctcaaaa
    16141 acaagcagat caactagaaa agctgaaaga gcaattagct atagctaaag agaaggctag
    16201 tcagcaaaag gaagagcttg aaactgccaa ggagcaggtt cagaaattat tggctgacta
    16261 ccaagctatt gccaaggagc aagaggagca gaaaacttcc tatcaagctc aacaaagcca
    16321 actctttgac cgtctggata atctcaaaaa caagcaggcc agagctcaaa gtttggaaaa
    16381 tatcctgaga aatcatagta acttttatgc aggtgttaag agtgttctcc aagaaaaaga
    16441 tcgcctaggt gggattattg gtgcagtcag tgagcatctg acctttgata tgcattatca
    16501 aactgcccta gaaattgcgc ttggagcgag tagccaacat atcatcgtag aagatgaaga
    16561 gtcggcaacc aaggctattg acttccttaa acggaacaga gccggtcgtg caacctttct
    16621 tcctttgacc actatcaagg cgcgtacgat ttctagtcag aaccaagatg ctatcactgt
    16681 aagcccaggt ttccttggga tggcagatga gttggtgact tttgatacta gactggaagc
    16741 cattttcaag aacttgctag ctacgacggc tatctttgat gccgtagaac atgcgcgtgc
    16801 agcagctcgc caagttcgtt atcaggttcg tatggtgaca ttggatggga cagaattacg
    16861 cacgggtggt tcctatgcgg gtggtgccaa tcgccaaaat aacagtattt tcatcaagcc
    16921 agaactggag caattacaaa aagaaattgc tgcagatgaa gcaagcttgc gttcagaaga
    16981 agcggctttg aagaccttac aagaccagat ggctacattg acagaaagat tagaagtcat
    17041 caaatctcaa ggagaacagg cacgtattca ggagcaaggc ttgtccctcg cttatcagca
    17101 aactagtcag caagttgaag aactggaaac tctttggaaa ctccaagaag aggaaataga
    17161 tcgtctttcc gagggagatt ggcaagcgga taaggaaaaa tgccaagatc gtcttgctgc
    17221 aatcgccagt gacaagcaaa atctggaagc tgagattgaa gagattaagt ctaacaaaaa
    17281 tgccatccaa gaacgctatc aaaacttgca ggaagagcta gcgcaagctc gtttgcttaa
    17341 gacagaactg caagggcaaa aacgttatga agttgctgat attgaacgct taggcaagga
    17401 attggacaat cttgattttg aacaagagga aatccagcgc cttcttcaag aaaaggttga
    17461 taatcttgag aaggttgata cagaattgct cagtcaacag gcggaagaag ccaaaactca
    17521 gaaaacaaat ctccaacaag gtttgattcg caagcagttt gagttggatg atattgaagg
    17581 tcaactggat gatattgcta gtcatttgga tcaggctcgc caacagaatg aagagtggat
    17641 tcgcaagcaa acacgtgctg aagccaagaa agaaaaggtt agcgagcgct tgcgctattt
    17701 acaaagtcaa ttaacagacc aatatcagat tagctatact gaagctctag aaaaggcgca
    17761 tgaattggaa aacctcaatc tggcagagca agaggtgcag gatttagaga aagctattcg
    17821 ctcactgggg cctgtcaata tagaagctat tgaccagtac gaagaagttc acaatcgtct
    17881 ggatttccta aatagccaac gagatgatat tttgtcagcg aaaaatctgc tccttgagac
    17941 cattacagag atgaatgatg aggtcaaaga tcgctttaaa tcaacctttg aggccattcg
    18001 tgaatccttt aaagtgacct tcaaacagat gtttggagga ggtcaggcag acttaatctt
    18061 gactgaggga gacttgttga cagctggggt tgagatttct gttcaacctc caggtaagaa
    18121 aatccagtcg cttaacctca tgagtggtgg tgaaaaagcc ttatcagctc ttgctttgct
    18181 tttttctatc attcgagtta agactatccc atttgtcatc ttggatgagg tagaggccgc
    18241 gctggacgaa gccaatgtta aacgttttgg ggattacctc aatcgatttg acaaggacag
    18301 ccagtttatc gtcgtaaccc accgtaaggg aaccatggca gcggctgatt ctatctatgg
    18361 agtgaccatg caagaatcgg gggtctcaaa aattgtttcg gttaagttaa aagatttaga
    18421 aagtattgaa ggatgacaat taaactagta gcaacggata tggacggaac cttcctagat
    18481 gggaatggac gctttgatat ggaccgcctc aagtctctct tagcttccta caaggaaaaa
    18541 gggatttact ttgcggtggc ttcggggcgc ggatttctgt ctctagaaaa attatttgct
    18601 gatgttcgtg atgacattat ttttatcgca gaaaatggca gtttggtaga gtatcgaggt
    18661 caagacttgt atgaagcgac catgtctcgt gagttttatt tgacgacttt tgaaaagctg
    18721 aaaacttcac cttatgtaga tatcaataaa ttgctcttga cggggaaaaa gggagcttat
    18781 gttctagata cggttgatga gacctatttg aaagtgagtc agcactataa tgaaaatatc
    18841 caaaaagtag cgagtctgga agatattaca gatgacattt tcaaatttac gaccaacttc
    18901 acagaagaaa cgcttgaagc tggggaggct tgggtcaatg aaaatgtccc tggtgttaag
    18961 gccatgacaa ctggctttga atccattgat attgttctgg actatgtcga taagggtgtg
    19021 gccattgttg aattggctaa aaaacttggc atcataatgg atcaggttat ggcttttgga
    19081 gacaatctaa atgatttgca tatgatgcag gttgtgggac atcctgtagc tcctgaaaat
    19141 gcacgacctg aaattttaga attagcaaag actgtgattg gtcaccataa ggaccagtcg
    19201 gttatagctt atatggaggg cttataatgg cagatataaa attaatcgca ttggacttgg
    19261 acggtacctt gctgactact gataaaaggc tgacggatcg caccaaggca actttgaaag
    19321 ctgcgagtga tcgtggtatc aaggtcgtat tgacaactgg tcgtccctta aaagccatgg
    19381 acttctttct ccatgagtta gggactgacg gccatgaaga tgagtatacc attactttta
    19441 atggtggatt agttcagaaa aatacaggag aaatccttga taaaacagtc ttttcatatg
    19501 atgatgtggc acgtttgtat gaggaaacag agaaattatc actgcctctt gatgccatct
    19561 cagaaggaac agtttatcaa atccaatcgg atcaagaaag tctttatgcc aaattcaatc
    19621 cagctttgac ttttgttcca gttgactttg aagacctgtc tagtcaaatg acctacaaca
    19681 aatgcgtgac tgcctttgct caagaaccct tggatgcagc cattcagaag atttctccag
    19741 aattgtttga ccaatatgaa atctttaaat cacgtgaaat gttgctagaa tggtcaccaa
    19801 agaatgttca taaagcaaca ggtttggcaa aactaattag ccatcttgga attgatcaaa
    19861 gtcaagtgat ggcctgtggt gacgaggcca atgacctctc tatgattgaa tgggcagggc
    19921 tcggtgttgc catgcaaaac gctgttcctg aagtaaaggc agccgcaaat gtagtgacgc
    19981 cgatgaccaa cgatgaggaa gctgtcgcct gggctatcga agaatatgtg ctaaaggaga
    20041 actaagatat gggattattt gaccgtctat tcggaaaaaa agaagaacct aaaatcgaag
    20101 aagttgtaaa agaagctctg gaaaatcttg atttgtctga agatgttgat cctaccttca
    20161 cagaagttga agaagtttct caagaagaag ctgtgcttga agaaagtcag gattcagagc
    20221 cagctgtagg ggtttctcaa gaagaaatag aagaattacc agaggaagag aagcttgagc
    20281 acgaaggaac tatagaagaa aataattctg aagttcttga agcagaaagg cctcaagcag
    20341 aagaaaccgt tcaggaaaaa tatgaccgca gtcttaagaa aactcgtaca ggtttcggtg
    20401 cccgcttgaa tgccttcttt gctaacttcc gctctgttga cgaagaattt tttgaggaac
    20461 tggaagaact gctgattatg agtgatgttg gtgtccaagt cgcttctaac ttaacggagg
    20521 aactacgtta cgaagccaag cttgaaaatg ccaagaaacc tgatgcactt cgtcgtgtca
    20581 tcattgagaa attggttgag ctttatgaaa aggatggcag ctacgatgaa agcatccact
    20641 tccaagataa cttgacagtt atgctctttg ttggtgtgaa tggtgttggg aaaacaactt
    20701 ctatcggaaa actagcccac cgctacaaac gaactggtaa gaaggtcatg ctggttgcag
    20761 cagatacctt ccgtgcgggt gcagtagctc agctagctga atggggccga cgagtagatg
    20821 ttccagtagt aactggacct gaaaaagctg atccagccag cgtggtcttt gatggtatgg
    20881 aacgtgccgt ggctgaaggt atcgatattc tcatgattga tactgctggt cgtctgcaaa
    20941 ataaggataa ccttatggct gagttggaaa agattggtcg tattatcaaa cgtgttgtgc
    21001 cagaagcacc acatgaaacc ttcttggcac ttgatgcatc aacaggtcaa aatgccctag
    21061 tacaggccaa agaattttcg aaaatcacac ctttaacggg aattgttttg actaagattg
    21121 atggaactgc tcgaggaggt gtggttctag ccattcgtga agaactcaat attcctgtaa
    21181 aattgattgg ttttggtgaa aaaatcgatg atattggaga gtttaactca gaaaacttta
    21241 tgaaaggtct cttggaaggc ttaatctaat cagaagcaaa aatcctgcaa ggtacaaact
    21301 tgcaggattt ttttattcga aacgaccatc ttgacgatag gcgatatctg gttgccaagt
    21361 ccatttggca tcgaattttt caagtaggtc aaagctggct tgaggtccca tgcttccagc
    21421 tttatagtca tgaagtgggg caccattttc ggcccagagc tcttcaatac ggtcaatcaa
    21481 cttccatgac gcaccaacct catcccagtg gctaaagtta gttgagttgt tatttaggac
    21541 atcataaatc aatttctcgt atggttctgg agaagcacca gttgcagtcg cgtctgtacg
    21601 ataatcaagt gagttaggag ccaagttaaa ttcttctcct acttgcttcc catttaggct
    21661 aagagagaag ccttctgttg gttgaatata gatggtcaaa atatttggag caagtggttc
    21721 tccaaagata gaatccattt gtttaaagac gatgttgaca tgagttcctt tttcagtcag
    21781 tcgtttacct gtacggaaaa agaaaggaac accacgaaat cgatcgctgt ctacaaagaa
    21841 ggcaccagat gtaaaggttt cagttgttga ttctggattc acatttggtt cgctacgata
    21901 agagatgtat ttcatgccat caatcttacc agagcggtat tgtccacgga taaagtgttc
    21961 tttgagttct tcatcagttg gatgatagag gtttttaaag accttaatct tttcagcacg
    22021 aatctcgtct tttgtgaagc ttgctggttt gtccatggcg aggagcgaaa gaagttgtag
    22081 agtgtggttt tggaccatgt cacggagggc accggattgg tcatagtagc caccacgttc
    22141 ttctacaccc aagcgctccg caaaggtaat ttgaacattg tcgataaaat ccttgttcca
    22201 aacgttttca aaaatcaagt ttgcaaagcg aactgcaaag atgctttgga tcatttcctt
    22261 accaagataa tggtcaatac ggaaaatttg ttcttcgtca aatgttgcta ggagttcgtc
    22321 attcaacttg cttgcagttg cgtaatctgt accaaatggt ttttcaacga tcaagcgctc
    22381 aaaacctttg ccatcgacaa tgttttcaga tttgaggtgt ttggcaatgg ttccaaagaa
    22441 ctgaggtgcc atagacaaga agaagagctt attgtgttca gcttggtatt tttcattaag
    22501 ctcagcttgt aattgacgca aagcaatata atgttccgaa tcattgacat catggctttg
    22561 atagtagaag tggctagcaa attcttgggc ttgctcggta ctatctgcca aatcaaggat
    22621 ggactcgaca actacagatt caaaatattc cttactccaa ggtctacggg cagttccaat
    22681 aacggcaaag tgcttggaaa gattgccgga ttgatatagt ctaaaaaggg aagggtagag
    22741 cttgcgttta gccaggtctc cactcgcacc gaaaattgta acaataacct tagatgacat
    22801 ctagctacct aatttctatt tttattccta gtcttgctag gtatgaggaa acctcatttc
    22861 ataaacttaa ttctaacata attttccgaa aaatcaaaaa ttccaatacg aggtagaaaa
    22921 actgcaagga aatccttaca gtttgagttt agacgtttaa gaccttatct aagaactctt
    22981 tcagacgagg gtgttgtggg ttatcaaaga tttggtcagg tgttccgtct tcaaggaact
    23041 cgccatctgc agtaaagata acgcggttgg caacctgacg agcaaatccc atctcatggg
    23101 ttacgataat catggtcatg ccttgctcag ccaattcctt cataacgtta agtacgtctc
    23161 caaccatctc agggtcaagg gcagaagttg gttcatcgaa gagcatgatg tctggattca
    23221 ttgctaggcc acgagcgatg gccacacgtt gtttttgacc acctgatagg ctatctggat
    23281 tggcattagc tttatctgct agtccaacct tttcaagcaa ctccattccc aattcctcag
    23341 cttcttcctt agtcatcaac ttgtgctcaa taggagcaaa ggtgatgttg tccaatacag
    23401 acatatgagg gaagaggttg aagtgttgga ataccatgcc gatattttca cggacgtggt
    23461 caacattggt tgttttttca gttaaatcat agccgttcac agtgatgtga ccgctagtga
    23521 cttcttctaa aagattgagg ctacggagga aagttgactt accagaacct gaaggaccga
    23581 tgatacaaac aacatctcct tcatagaact tagtcgtaat tccttttagg acttcatttt
    23641 ttccatagta cttgtgtaaa tcatttacat caatttttaa ttttgccatt aacgaatcct
    23701 cttttctaag cgtttcgcta gtctagtcaa aagtgtgata attacaagat agaagatagc
    23761 aaggattgca tacatcttga aactttggta gttacgagca atgataatct taccagtttg
    23821 gaagagttca accaaaccga tagcagatac gatagttgta tctttaagag cgataacgaa
    23881 ttggttgaca aagtttggca acatcaattt agttgattgt ggcaagataa tcttacgcat
    23941 ggtttttcca taagagatac ccaagcttcg gctggcttcc atttggccaa ctggaacggc
    24001 ctgaatacca ccacgaacga tttcagcgat ataagcagcc gcattgagtg agagggcaat
    24061 tgttccagct acaaagtcgt taattgggct ttgttggcct gtgatagact cgatgaagtt
    24121 tggaattccc cagaagatga aggctgcaag aatcatcaat ggaataccac gaataacgtc
    24181 aacgaaaatc tcagagatga cgcgaagaga tttgtatggg ctaacgctaa acataccgaa
    24241 gataattccg atgacaatgg caatagcaaa tgagataaga gctagagcaa gagtgatacc
    24301 aagaccgcta aggagttgtt tgtagttgtt ttgaagcaag ccccagagcg ttgtttcgtc
    24361 aacagtactt gttgaagcag ttgaagattc gctagctagg tatttgtcaa gaatcttttg
    24421 gaattcaccg tttgctttaa ggtttgcaag tccgttgttg aacatttcaa tcagttctgg
    24481 atttgctcct tttttaacgg caaaggctgt ttcaccgatt ggagttccag agattggagt
    24541 tttcaatttt tgaccttggc tgatagaata tttgagaaca ggttcatcat ccataacggc
    24601 atcaatggca ccagtgttta aactgtcata cattgaagaa ccatcagcaa aggttttgat
    24661 tttgtaaccg tatttgcttt gattttctgt taggaaggtt tgagaagcag ttccgttttt
    24721 aacaccgact gtctttcctt ttagatcttc ataagaagca atattgcttg attctttgac
    24781 accaagaatg gtattagcag tgtagtatga ttctgagaag tcaaaagttg ccttacgagc
    24841 atctgtgaca gacataccag caatgatacc atcggcttga ccagcttgga cagcactgat
    24901 agcagcatca aaaccagggt tggtgatttc aatttcaaaa ccttggtctt tagcgattgc
    24961 cttaatcaat tccatatcaa taccagtgta ttggttgctt gaattttgga aaacaaaagg
    25021 tgcaaaagaa gaatcgctgg caatgatata tttagcctta acaggaatag cttttaatcc
    25081 tgcgagagta gttgtagttg gcactgctga agatgatgaa gcagtccatt tcttgataat
    25141 tttatcaaga ctaccatctt ttttcatttc agccaaggct tggttaaatt cagtaaccag
    25201 gtgctcgtat ttacttcctt ttttcacacc gaaagcaaaa cttcctacag cttcaccatc
    25261 catttcaata tggaggtctt gaccttggtt aatggcatat tcgataacag gtttgtcatc
    25321 catcatggca tcgatggcac cagcactcaa gctgttgttc attaaatcac cagtgtcaaa
    25381 tgttttaata gtaaagccgt atttatcttt gattgtttca aggaaacgtt gagcggcagt
    25441 tccgttttta acaccaacgg ttttgccagt taattggtcg tacttgctaa ttttgtgtga
    25501 ctttgtagta gcaatgacaa cttttgtatc atagtaagta tcagacatgg tgaagacttt
    25561 ttcacgttct ttagtctttg tcatccctgc catgatagcg tcggcttgcc cagcttgaac
    25621 cgcattgact gctgcgtcaa atccaggata ggacatctga atgttccagc ctttaatctc
    25681 agcgactttg ttaataatgt caacatcaat tcctttataa gtttgatctg aatctttaaa
    25741 ctcaaaaggt gcataggcgg tatcagaaac aatcttaatc gtttctgctt tggcaatacc
    25801 taatgagaaa attgggaata aaattagcaa aaatgctaga aattttttct tcatttttag
    25861 tctccttttc cgaatattct ctcattatat cagaaaaagt aaaaaaaggc aaatttttat
    25921 atttttcgtg tcagaaaata taacattgat ttttcctttt ctttcttgaa ttgct
//
LOCUS       DAVLIK010000027        25472 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLIK010000027 DAVLIK010000000
VERSION     DAVLIK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.027"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            817..1299
                     /locus_tag="VXE87_001273"
     CDS             817..1299
                     /locus_tag="VXE87_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEV0842812.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            1296..1892
                     /locus_tag="VXE87_001274"
     CDS             1296..1892
                     /locus_tag="VXE87_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0842813.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            1873..2364
                     /locus_tag="VXE87_001275"
     CDS             1873..2364
                     /locus_tag="VXE87_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842814.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            2744..4897
                     /locus_tag="VXE87_001276"
     CDS             2744..4897
                     /locus_tag="VXE87_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0842815.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            4910..6259
                     /locus_tag="VXE87_001277"
     CDS             4910..6259
                     /locus_tag="VXE87_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0842816.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATIEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            6429..7136
                     /locus_tag="VXE87_001278"
     CDS             6429..7136
                     /locus_tag="VXE87_001278"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0842817.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            7338..11063
                     /locus_tag="VXE87_001279"
     CDS             7338..11063
                     /locus_tag="VXE87_001279"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0842818.1"
                     /translation="MDKRIFVEKKADFQVKSESLVREFQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            11156..12598
                     /locus_tag="VXE87_001280"
     CDS             11156..12598
                     /locus_tag="VXE87_001280"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0842819.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            12635..13657
                     /locus_tag="VXE87_001281"
     CDS             12635..13657
                     /locus_tag="VXE87_001281"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0842820.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            13654..14199
                     /gene="purN"
                     /locus_tag="VXE87_001282"
     CDS             13654..14199
                     /gene="purN"
                     /locus_tag="VXE87_001282"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0842821.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            14283..14792
                     /locus_tag="VXE87_001283"
     CDS             14283..14792
                     /locus_tag="VXE87_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0842822.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            14817..16364
                     /gene="purH"
                     /locus_tag="VXE87_001284"
     CDS             14817..16364
                     /gene="purH"
                     /locus_tag="VXE87_001284"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0842823.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFSDNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            16486..17748
                     /gene="purD"
                     /locus_tag="VXE87_001285"
     CDS             16486..17748
                     /gene="purD"
                     /locus_tag="VXE87_001285"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0842824.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVIYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            18151..18639
                     /gene="purE"
                     /locus_tag="VXE87_001286"
     CDS             18151..18639
                     /gene="purE"
                     /locus_tag="VXE87_001286"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0842825.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPIIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAAIFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            18626..19717
                     /gene="purK"
                     /locus_tag="VXE87_001287"
     CDS             18626..19717
                     /gene="purK"
                     /locus_tag="VXE87_001287"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0842826.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVDELGEGIDF"
     gene            19727..19954
                     /locus_tag="VXE87_001288"
     CDS             19727..19954
                     /locus_tag="VXE87_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV0842827.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            20017..21315
                     /gene="purB"
                     /locus_tag="VXE87_001289"
     CDS             20017..21315
                     /gene="purB"
                     /locus_tag="VXE87_001289"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0842828.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(21370..25308)
                     /gene="strH"
                     /locus_tag="VXE87_001290"
     CDS             complement(21370..25308)
                     /gene="strH"
                     /locus_tag="VXE87_001290"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0842829.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWTDTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASDLGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVLGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
BASE COUNT         7032 a         4900 c         5893 g         7647 t
ORIGIN      
        1 tttgtatttt ctagatatta ttggatattt ttatttatcc attactcttt gtttgatagc
       61 tattcaaatt atttctttaa ttctacctag tttgttttca attataagta aattgttctt
      121 atttttatct ataggactat tgtctataga acaaggacaa gttgtaattt atgtcatact
      181 actcaattat tttattttag ttatggggat attagataat catgcgagta atttctattt
      241 taaaagcagt cgaatgagtc aaaaaagatt tcgtagcagt ctatttatat tgcttcgttt
      301 ttgttggtta aataaagggt taactttttc ttttattttg attagtattc ttctttccta
      361 tctattttgg tatatgatga cgatgttatc aattgatgac acaaaaatac caatattatt
      421 tctttatacc tcaatatata ttacattaat ggaggcaata atagggaatc ataaatcctc
      481 aattggggta gatctagctt tatttcaatt atctgctctt aatcattcta aaatgaattt
      541 cttttttaag aatgcacaac taatgatgtt gacgcattta atctctttct tacaattttc
      601 attgttgtta tgtttgattc cggtgacaag ttatagtaat gatataaaaa gtattttgtt
      661 gaatttgtta ttgattccat tcaattattt tatagcctat gtctattata agaaagctct
      721 atttttaatt aaaggtacag ttagtttatt gagatggagt tttctggttt tatattgttt
      781 tctgataata tttgtaattt tagtaggggg cattagatga gaaaaagtgg ttttctgatt
      841 tactatgtgt tattttgtat agtctgtttt ttactaggtt tacttttaag ctttatatta
      901 aaaaatgaga cttttgctac tatacctccg aaactggaat tacaatttac attgacagtt
      961 ttacaggcaa attctacaaa ttttttgcta tatctattct gttttccgat ttcgccctta
     1021 ttgcaacttt ttgatttgct atctttagga atacaattgg gtatatctgg tcagatgatt
     1081 ggaatagtag ctacaataaa aggaatatta cctcatgctc ttattgaaat accgaatttt
     1141 atttggtatc aaggtatgag tcagtatctt ttataccgat tattgaagga taggggaatt
     1201 aaaaatatac ttatttatat aaaaagtaat ttaaaatggt atatcatttc ttatctttta
     1261 ttaattttag cagcgttgat agagggaatt aaattatgaa aattgaaaat gaatctaaaa
     1321 gttatgataa atgtatattg aaaaatatat cactagagat tgataaggga atttacagag
     1381 ttgaaggaga gaatggttca ggaaagagca cccttctaca acttttagct gggctagaga
     1441 cttttgatag tggtttaaag aattgtgtct ccaaagatgt actatacctt gataccaatc
     1501 agcttggggt tgttccattt actatagaag aaaatttgca gttgttgtgt gattcttttc
     1561 aaatccatct atcatttgag gataaagaac aaattaatac tttttttgat aataaaatcg
     1621 gagataacta tatgacagca tctactggaa caaaattcaa attaggctta tccttaattt
     1681 ttgctaaaaa ttgggattat atttttattg atgagacttt atcaacagtg gatgcaagaa
     1741 gtattgatat gattgctaaa cgcttaattt ccatgaaaga aagctctact attatatatg
     1801 tatctcataa tttattgaat caagaattga ttagcaaatc tcaaaggatt ttaatagagg
     1861 aaggacgggt ttatgaaatt tcaaacaaat aatagtttat acaaattaat gaatctgatt
     1921 atttatcttt ttcttttata tttgtttatt gatttactga tgaagtcggg aattttagat
     1981 gaacaaattg ataaattatc tgaactatct aatcttttta caattaaaat agaaacaata
     2041 ttgacagtga tttctgttgt tttcacattt atagcaactc ttattgaata tggattttct
     2101 ctctttctga ttacattatt ttttgataag aataagagga actttggaga tattctttta
     2161 tctaaaaata taaccttaag ttttagcatt ttactttgtt atttatttaa tccatcggat
     2221 ataaagtttg cctatttcag cgtattgaca gtattactaa ttgggataac aaattatgcg
     2281 agatttaaaa atttaagatt gacagtagtg ttttctgtac catttttatt taatgctata
     2341 atgtctatta taaatagttt ttagaaatac taaaattttt ttctttactt aataatgata
     2401 tgaaatcatt tcggttttgt taacttgtaa ttcttatatt ttctaggtag aacgtttgtt
     2461 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
     2521 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
     2581 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
     2641 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
     2701 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
     2761 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
     2821 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
     2881 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
     2941 agccattaag gcggatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
     3001 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
     3061 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
     3121 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     3181 ttataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     3241 cttgattgcc aatatcgttt tggcaacact cttggtaacc gggattaaca ttgtgggttc
     3301 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     3361 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     3421 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     3481 caagcatgtt tttcacctcc ctatgtcctt ctttgcgaca cgcaggacag gggagatcgt
     3541 gtctcgtttt acagatgcta acagtatcat cgatgcgctg gcttcgacca tcctttcgat
     3601 tttcctagat gtgtcaacgg ttgtcattat ttcccttgtt ctattttcac aaaataccaa
     3661 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     3721 gaagccgttt gaaaagatga atcgggatac catggaagcc aatgcggttc tgtcttcttc
     3781 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     3841 ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     3901 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttgctta atgtcggcat
     3961 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     4021 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     4081 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     4141 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag atatgacctt
     4201 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     4261 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     4321 ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     4381 caatctcaat cagattgata aaaaagccct gcgccagtac atcaactatc tgcctcaaca
     4441 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     4501 gacacaggaa gatatcttac gggcggtcga attggcagag attcgagagg atatcgagcg
     4561 catgccactg aattatcaga cagaattgac ttcggatggg gcagggattt caggtggtca
     4621 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     4681 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcatggc
     4741 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     4801 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     4861 acagggaggc ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     4921 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     4981 tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg cagagaagga
     5041 gatgagtttg tccactagag ctactatcga acccagtcgt atccttgcaa atatccagtc
     5101 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     5161 ggatcttttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     5221 tcagttggac atgctaaagg atcaaaaaaa gcaattagag tatctgcaaa agagcctgca
     5281 agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca cctttcgcga
     5341 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     5401 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     5461 agaggctaaa attcgcgatt accagacagc taagtcagct atggaaacag gtgcttcctt
     5521 ggccagtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     5581 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     5641 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     5701 agggttaagc agtcaattgg aatcccttaa atcccaacat ttggcaaagg ttggtcagga
     5761 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     5821 tcttttagac aaggggaaaa ttacggcgag tgaggatggg gtgcttcatc ttaatcctga
     5881 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     5941 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     6001 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aacttttcct
     6061 agattcaact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     6121 taaaatagag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     6181 ggaaggccgc ttgcagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     6241 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     6301 aagattcttc ttgcagtttt ttctttacaa tttttgaaaa acatctacta tttattcggt
     6361 taaattcttg tgttttttgg ttttttgtgg taaaatgtgc tcaagtaata cgaaaggcga
     6421 actttaaaat gtcaaaacaa ttgatctatt cgggaaaagc taaagatatc tatacaactg
     6481 aggatgaaaa tcttattatt tcaacttaca aggaccaggc gactgctttc aacggtgtca
     6541 agaaggagca gattgcaggt aagggagtct tgaataatca gatctcatct tttatttttg
     6601 agaaattaaa tgcggctggt gtggcgactc actttgtgga gaaactttca gacacggaac
     6661 aactcaataa aaaggttaag attattcctt tggaagtcgt gctccgcaac tatactgctg
     6721 gttctttttc aaaacgtttt ggtgtggatg agggaatcgc cttggagact ccgattgtcg
     6781 aattttacta caaaaatgat gatttggatg atccatttat caatgatgag catgtgaaat
     6841 tcctacagat tgcgggtgac cagcagattg cctacttgaa ggaagaaacg cgtcgtatca
     6901 atgaactatt gaaagtctgg tttgctgaga ttgggcttaa attgattgac tttaagctag
     6961 agttcggttt tgacaaggat ggcaagatta tcttggcaga cgaattttca ccagataact
     7021 gccgcttgtg ggacgctgat ggcaaccaca tggataagga tgttttccgt agaggattgg
     7081 gagaactaac cgacgtttat gagattgttt gggaaaagtt gcaggaattg aaataatctg
     7141 tttgcaacgg aaaaccttcg tctctcaact aaaaggactc aggctgaaaa ggtcccccag
     7201 accttttcac tctgtagaga actaggtgaa ctaacagatg tttacgaaat tgtctgggaa
     7261 aagttgcagg gtttaaaata acaacctcaa ggctgtttgg gaatattgca agagctgaaa
     7321 taaaggaata agaattgatg gataaacgta tttttgttga aaaaaaggct gattttcagg
     7381 tcaagtcaga gagtttggtt agagagttcc agcacaactt gggactgtca agcttgaaaa
     7441 gtattcgtat tgtgcaagta tatgatgtat ttgacttggc tgaggacttg tttgcacctg
     7501 cagagaagca cattttctct gagcagggaa ccgaccatgt tttagatgaa gtatctgtgc
     7561 aggcggatct tgctaactat gctttctttg ccattgaaag tctgccaggg cagtttgacc
     7621 agcgtgcagc ttcgtcacag gaagccttgc ttttgttggg aagttcgagt gacgtgacag
     7681 tcaacacagc ccaactttac ttggtgaata aagatattga tgcgactgag ttggaagctg
     7741 tcaaaaacta cctgctcaat ccagttgatt ctcgtttcaa ggatatcacg acagggattg
     7801 ccaagcagga gttttcagag tcagacaaga ccattccaaa attgactttc tttgaaagct
     7861 atacagcaga agactttgct cgctacaagg ccgagcaagg gatggccatg gaagtggatg
     7921 atttgctctt tatccaagac tactttaagt caatcgggcg cgtgccaact gagactgaac
     7981 tcaaggtttt ggacacttac tggtctgacc actgccgtca tacgactttt gagacagagt
     8041 tgaaacacat cgacttttca gcttctaaat ttcaaaagca attgcagtca acctatgaca
     8101 agtatattgc catgcgcgag gagttaggtc ggtctgaaaa accacaaacc ttgatggata
     8161 tggcgactat tttcggtcgt tatgagcgtg ctaacggacg attggatgat atggaagtct
     8221 ctgacgaaat caatgcctgc tcagttgaaa ttgaagtgga tgttgatggt gtcaaggaac
     8281 cttggctcct catgtttaaa aatgaaaccc acaaccatcc aacagaaatt gagccatttg
     8341 gtggagcggc tacctgtatc ggtggagcta ttcgtgatcc gttgtcaggc cgttcctatg
     8401 tttaccaagc catgcgtatt tcaggtgctg gtgatattac agcaccgatt tcggaaactc
     8461 gtgctgggaa attgccacaa caagtcattt ctaaaacagc agctcatggt tattcttcat
     8521 atggtaacca gattgggctt gccacaacct acgttcgtga atacttccac ccaggctttg
     8581 tagctaaacg tatggaactt ggtgccgttg ttggtgcggc tcccaagggc aatgttgtcc
     8641 gtgaaaaacc tgaagcaggt gatgtgatca tccttctcgg aggcaaaaca ggtcgtgatg
     8701 gtgtcggtgg tgcgacgggc tcttctaagg ttcaaacagt tgagtctgta gagactgctg
     8761 gtgctgaggt tcaaaaagga aatgccatcg aagaacgcaa gattcagcgc ctcttccgta
     8821 atggcaatgt cactcgtctg atcaagaagt ccaatgactt tggggcaggc ggcgtctgtg
     8881 tggctatcgg tgaattggca gacggtcttg aaatcgacct caacaaggtg cctcttaaat
     8941 accagggctt gaatggtaca gaaattgcca tctctgaatc acaagaacgg atggcggtcg
     9001 tggttcgtcc tgaagatgtg gataccttcg ttgccgaatg taacaaagaa aatattgatg
     9061 ctgttgtggt ggcgacagta actgaaaaac caaatcttgt catgcactgg aatggtgaga
     9121 caatcgttga cttggagcgt cgtttccttg acaccaatgg tgtgcgcgtg gttgtcgatg
     9181 ccaaagttgt ggacaaggat gtcaaactcc cagaagagcg tcaaacatct gctgaaacac
     9241 tggaatcaga tacccttacg gttctatctg acctcaacca tgcaagtcaa aaaggattac
     9301 agactatctt tgactgctct gttggacgct caacggttaa tcacccactt ggtggtcgtt
     9361 accaactcac accaactgag gcatctgtgc agaaattgcc agttcaacac ggtgtgactc
     9421 atactgcgtc ggtcattgct caaggtttca acccatatgt agctgaatgg tctccatacc
     9481 acggtgctgc ttatgcggtt atcgaagcaa ctgctcgttt ggtggctgct ggtgccaact
     9541 ggtctaaggc tcgtttctct taccaagaat atttcgagcg gatggacaag caagcagagc
     9601 gtttcggtca gccagtagct gctcttctag gttctattga agcacaaatt cagcttggct
     9661 tgccatctat cggtggtaag gactccatgt ctggtacctt tgaagaattg accgttccgc
     9721 caaccttggt tgcctttggg gtgacgacgg cagatagccg taaggtgctc tctccagaat
     9781 ttaaagctgt tggggaaaat atctactaca tcccaggtca agccctctct gcagagattg
     9841 attttgactt gattaagaaa aattttgctc agtttgaagc aagccaagct gaccataaag
     9901 tgacgtctgc atcagctgtc aaatacggtg gtgtagttga aagtttggct cttgctacct
     9961 ttggaaacta tattggtgca gaggtgacct tgcctgaact taaaacagct ttgacagctc
    10021 aattaggcgg ctttgtcttc acatctcctg aagaaattgc tggagtagag aagattggac
    10081 aaacgaaagc agactttaca ctgactgtca acggtgtgaa gctagatgga cacaagcttg
    10141 acagtgcatt tcaagggaca ttggaagaag tttacccaac agaatttacc caagcgaaag
    10201 aactagaaga agtaccagct gtggcatcag atgttgtgat taaagccaaa gaaaaggttg
    10261 aaaaacctgt ggtttacatc ccagtctttc caggaaccaa ctcagaatat gattcagcta
    10321 aggccttcga aaaagaaggt gcagaggtca atttggtgcc attcgtgacc ttgaatgaag
    10381 aagctattgt caagtcagtt gaaactatgg ttgacaatat cgacaagact aatattctct
    10441 tctttgccgg tggattctcg gctgcggatg aaccagatgg ttcagctaag tttatcgtca
    10501 atatcctgct taatgaaaaa gtgcgtgtgg ctattgatag ctttatcgcc cgtggtggct
    10561 tgattatcgg tatttgtaat ggattccaag ccttagtcaa atcgggtctc ctaccatacg
    10621 gaaactttga agatgctaac agtactagtc caaccctctt ctacaatgat gccaaccaac
    10681 acgtggccaa gatggtggaa actcgcattg ccaataccaa ctcaccatgg ttggctggtg
    10741 tgcaagtggg cgatatccac gctattcctg tttcgcacgg tgaagggaag tttgtcgtga
    10801 cggctgagga atttgcagag ctccgtgaca atggacaaat tttcagccaa tacgttgact
    10861 ttaacggtaa accaagtatg gattctaagt acaatccgaa tggttctgtc catgccatcg
    10921 aaggaattac cagcaagaat ggtcaaatca tcggtaagat gggccactca gaacgttatg
    10981 aggatggtct tttccaaaat atcccaggca ataaagacca acacctgttc gcatcagcgg
    11041 ttaaacattt cactggaaaa taagacttac agattttcta atagatagta tcagtaatgt
    11101 aaaagtcatg taaatctagc tcttgatgat tacaaatgaa aattaggtat aaaaaatgac
    11161 atacgaagta aaatctctta atgaagaatg tggtgttttc ggtatttggg gacatccaga
    11221 tgctgctaag ttgacctatt ttggactcca cagtcttcaa caccgtggtc aggagggggc
    11281 aggaatcctc tccaatgatc aaggacaact gaagcgccat cgtgacatgg ggcttttatc
    11341 agaagttttc agaaatccag ccaatttgga taaattgaca ggagctggtg cgattgggca
    11401 tgtgcgttat gcgactgctg gcgaagcttc tgttgataac atccagccct tcctcttccg
    11461 ttttcacgat atgcagtttg gcttggctca taatggaaat ctgaccaatg cagcctctct
    11521 caagaaagaa ctggaacaaa gaggagcaat tttcagcgcg acttcggact ctgaaatctt
    11581 ggctcacctc attcgtcgta gtcataatcc tagcctgatg ggcaaaatca aggaagcgct
    11641 cagccttgtc aaaggtggtt ttgcctatat cttgctgttt gaggacaagt tgattgcggc
    11701 tcttgaccct aatggctttc gtccgctttc tatcgggaaa atggccaacg gagcggtggt
    11761 tgtttcctct gaaacctgtg cttttgaggt cattggtgcc gagtggattc gtgatttgaa
    11821 gccaggtgag attgtgatca ttgatgacga gggcattcag tatgacagct atacagatga
    11881 tactcagttg gcgatttgtt ctatggagta tatctacttt gctcgccctg attctaatat
    11941 ccacggtgtc aatgtccata cggcacgtaa gagaatggga gcgcaattgg cgcgagaatt
    12001 taagcatgag gcagatattg tagttggtgt gcccaattct tccctaagcg cggctatggg
    12061 atttgcggaa gaatcaggct taccaaatga aatgggtctg atcaaaaacc aatacaccca
    12121 gcgaactttt atccaaccga ctcaagaatt gcgggagcaa ggagtgcgga tgaaactgtc
    12181 tgctgtttcg ggtgttgtca aaggcaaacg tgtggtcatg gtggatgatt ccattgtacg
    12241 tggaacaacc tctcgtcgta tcgttcagct cttgaaagaa gcgggtgcga ctgaggttca
    12301 cgttgccatt ggaagtcctg cactagcgta tccatgtttc tacgggattg atatccagac
    12361 ccgtcaggag ctgattgcag ccaatcatac ggtcgaagaa actcgccaaa tcattggtgc
    12421 ggacagtctg acttatcttt caattgatgg cttgattgag tcgattggta tcgaaacaga
    12481 tgcgccgaac ggtggtctct gtgtcgctta ctttgacggt gactacccaa cgcctctcta
    12541 tgactacgaa gaagactatc gtagaagttt ggaagaaaag accagttttt acaagtaggc
    12601 gacagattct ccattaaaga aaaggaaaaa acaaatgaca aataaaaatg catatgccca
    12661 gtcgggtgtg gatgttgaag cgggttatga agttgttgaa cggattaaaa agcacgtggc
    12721 ccgtacggag cgtgcaggtg tcatgggagc tcttggtggc tttggtggta tgtttgacct
    12781 ttccaagact ggggttaaag aacccgtctt gatttcaggg actgacggtg tcggaaccaa
    12841 gctcatgttg gctatcaagt acgacaagca cgataccatc gggcaggact gtgtggccat
    12901 gtgtgtcaac gacatcattg ctgcaggtgc ggaacccctc tattttctcg actacgtagc
    12961 gacagggaag aatgaaccag ctaagctaga acaagtggtt gctggtgtgg cagaaggttg
    13021 tgtgcaggct ggtgctgccc tcatcggtgg ggaaacggct gaaatgccgg gcatgtacgg
    13081 cgaagacgac tatgacttgg ctggttttgc ggtcggtgtg gctgaaaaat ctcaaatcat
    13141 tgacggttca aaggtggtag agggagatgt tcttctcgga cttgcttcaa gtgggattca
    13201 ctcaaatggt tactctttgg ttcgtcgtgt ctttgcggat tacacaggtg aggaagtcct
    13261 accagaattg gaaggcaaga aacttaagga agttctactt gagccgactc gtatctatgt
    13321 caaggctgtc ttgccgctca tcaaagaaga gttggtcaac ggcattgccc acatcacagg
    13381 tggtggcttt atcgaaaatg tccctcgtat gtttgcagat gacctagctg ctgaaattga
    13441 tgaaagcaaa gttccagtgc ttccaatttt caaagccctt gaaaaatatg gtcagattaa
    13501 acacgaagaa atgtttgaaa tcttcaatat gggtgtggga cttatgttgg cggtcagccc
    13561 tgaaaatgta gagcgtgtaa aagaattgtt ggatgaagca gtctatgaaa ttggtcgcat
    13621 cgtcaagaaa gaaaacgaaa gtgtcattat caaatgaaaa aaatagcggt ttttgcctct
    13681 ggtaatggct caaattttca ggtgattgcc gaagaatttc cagtggagtt tgtcttttca
    13741 gaccatcgtg atgcctatgt gcttgagcgt gcaaagcagc tcggcgttct gtcctatgct
    13801 tttgaactca aggagtttga gagcaagaca gactacgaag cagcccttgt cgaactcttg
    13861 gaagaacacc agattgactt ggtttgccta gcaggctaca tgaaaatcgt tggaccaacc
    13921 ttattgtcgg cttatgaagg tcggattgtc aacattcatc cagcctactt gccagaattt
    13981 ccaggagctc atgggattga ggatgcttgg aatgctggcg tgggtcagtc tggtgtgacc
    14041 attcactggg tggattcggg tgtggataca ggccaggtca tcaaacaggt tcgtgtgcca
    14101 cgactagctg atgataccat tgacagattt gaagctcgca tccatgaagc agagtacagg
    14161 ttgtatccgg aagtagtgaa ggctctattt acagattgac tttttgatga ttcatatgat
    14221 atctttgatt ttaaattgga gtcagtgttt gttgaagacg gcttcaaacg gaggtatttg
    14281 taatgttaga atctaaaaaa acaactcgat atgtatttta tgtctatctg atgttattaa
    14341 cttggggaat cttatttaag tttgaaacaa atcctgaatt tatagcattt ttcttagctc
    14401 caaggtatat caattggatt ccattttcag aaccactaat agtcgatgga aaaattgttt
    14461 ttgctgaaat gttatttaat ctgatttcct ttattccatt aggtgtttgt ttccctttga
    14521 taaaaactaa tttatctagt ttaagaatag tcgggacagg tttcttgatt agtttattgt
    14581 ttgagtgctt acagtatatt ttagcaatag gtataacaga tataacggat ttgactttaa
    14641 atacgctagg tgtctgtgta ggcttactga tttatcaaat ttttataaga gtgttcaaat
    14701 cacagactag aaaatggatc aatatcttag gtatgcttag ccttggtttt gcttatcttg
    14761 ttttactgtt actgcattta attggtgttt aactaatgat taaaaaggag aatataatga
    14821 ctaaacgcgt cttaatcagc gtctcagaca aagcgggcat tgttgaattt gcccaagaac
    14881 tcaaaaaact tggttgggag attatctcaa caggtggaac taaggttgcc cttgataatg
    14941 ctggggtgga taccattgct atcgatgatg tgactggttt cccagaaatg atggacggtc
    15001 gtgtgaagac cctccaccca aatatccacg gagggcttct cgctcgtcgt gacttggata
    15061 gccacttgga agcggctaag gacaacaaga ttgagctcat tgaccttgtg gtggtcaacc
    15121 tttacccatt taaggaaact atccttaaac cagatgtgac ttatgctgat gcagttgaaa
    15181 atatcgatat tggtgggcca tctatgcttc gttcagcagc gaaaaatcat gccagtgtta
    15241 cagttgtggt agatcctgct gactacgctg tggttttgga cgaattggca gcaaacggcg
    15301 aaacctctta tgaaactcgc caacgtttag cagccaaagt atttcgtcac acagcggctt
    15361 atgacgcctt gattgcagaa tacttcacag ctcaagtggg tgaaagcaag cctgaaaaac
    15421 tcactttgac ttatgacctc aagcaaccaa tgcgttacgg tgagaatcct caacaagacg
    15481 cggactttta ccagaaagct ttgcctacag attactctat tgcttcagcc aaacagctca
    15541 acgggaaaga attgtcattt aataatatcc gtgatgcaga tgctgctatc cgtatcatcc
    15601 gtgacttcaa agatagtcca accgttgtgg ctctcaaaca catgaatcca tgtggaattg
    15661 gtcaagctga tgacatcgag actgcttggg actacgctta tgagtctgac ccagtatcta
    15721 tctttggtgg gattgtcgtc ctcaaccgtg aggtggatgc tgcgacagct gagaagatgc
    15781 acggcgtttt cctcgaaatc atcattgccc caagctatac ggatgaagcg ctagctattt
    15841 tgatcaataa aaagaaaaac ttgcgtatcc ttgccttgcc atttaatgct caagaggcta
    15901 gcgaagtgga agcagaatac acaggtgtag tcggtggact tctcgtgcaa aatcaagacg
    15961 tggtcaagga aagcccagct gactggcaag tggtgaccaa acgtcagcca actgagacag
    16021 aagcgactgc tcttgagttc gcttggaagg ctatcaagta cgtcaaatca aatggtatta
    16081 tcgtgaccaa cgaccacatg acacttggtg ttggtccagg tcaaaccaac cgtgtggctt
    16141 ctgttcgcct tgccattgac caagccaaag atcgtctgaa cggggcggtc cttgcttcag
    16201 atgccttctt cccattttcg gataacgtgg aagaaatcgc caaagcagga attaaggcca
    16261 tcatccagcc cggtggctct gtccgtgacc aagaatccat cgaagcagcg aataaatacg
    16321 gcttgactat ggtctttaca ggtgtgagac attttagaca ttaagaagat aaaagggaag
    16381 aaaacagttt ctttcctttt ttggcttaaa atgctaactg aaacaagatt aaaacgaact
    16441 tttttgatat aatgttggta aataattcgc aaaagaggtt gaggaatgaa actgcttgtt
    16501 gtcggttctg gtggtcgtga gcatgcgatt gctaaaaagt tacttgaatc aaaagacgtg
    16561 gaaaaagtct ttgtagctcc tgggaatgat gggatgactc tggatggttt ggaattggta
    16621 aatatctcta tttccgaaca ttctaaattg attgacttcg caaagaccaa tgatgttgct
    16681 tggaccttta tcggtccaga tgatgccctt gctgctggta tcgtggatga ttttaaccaa
    16741 gctgggctta aggcctttgg tccgactagg gctgcagcgg agctggagtg gtccaaggat
    16801 tttgccaagg aaatcatggt caaatatggt gtttcgacag cagcctatgg cacattttca
    16861 gatttcgagg aagccaaggc ctatatcgaa aagcatggtg cgcctatcgt agtcaaggcg
    16921 gatggcttgg cgcttgggaa gggtgtcgtc gttgctgaga cggttgagca agcggtcgaa
    16981 gccgctcatg agatgctttt ggacaataaa tttggtgact caggtgcgcg cgtggttatt
    17041 gaggaattcc ttgaaggaga ggaattttca ctctttgcct ttgtcaatgg tgataagttc
    17101 tacatcatgc caacggctca ggaccacaaa cgtgcctacg atggcgacaa agggcctaac
    17161 acgggtggta tgggtgccta tgcgccagtt ccacacttac cacagagtgt agttgataca
    17221 gcggttgaca ccattgtcaa gccagttcta gaagggatga ttaaagaagg tcgcccttat
    17281 ctaggtgtca tttacgcagg gcttatcttg acagcagacg ggccgaaggt catcgagttc
    17341 aactctcgat ttggagatcc tgaaactcag attatattgc ctcgtttgac ctctgacttt
    17401 gctcaaaata tcacagatat cctggatagc aaggagccaa atatcatgtg gacggacaag
    17461 ggtgtgactc tgggtgtggt tgtcgcatcc aagggctacc cgctagacta tgaaaggggc
    17521 gttgagttgc cagccaagac agaaggcgat gtcatcacct actatgcagg ggctaagttt
    17581 gcggaaaata gcagagcact gctctcaaac ggcggacgag tttatatgct ggttaccaca
    17641 gtagccaccg tcaaagaagc ccaagccagc atctaccaag aactatccca acaaaaaata
    17701 gaaggactct tctaccgaac agatatcgga agcaaggcaa ttaagtaaag atataagaat
    17761 aacgcgacgc agtcgccaaa cacgataatg gtcgtcgtgg tgaaaagacc agaacagtga
    17821 atgttctggt cagggggaaa ctttgagacc ttaggctcaa agtttaggaa tgaaaccgaa
    17881 ggtttgcttc cgcctccatc acctaagacc attatcaaaa agaaaaataa aaattcacaa
    17941 aatacgttaa tggtcgtatg gtttgcgagc gttagcgagc aaatatagaa taatcaccgc
    18001 cgttgtgaaa gaacgattgg atgataatcc aatcgttcag ggaaattgga agaccttggg
    18061 tttccaattt aggcatgaga cacctttggt ggctgctgcc gtccctcaca agctaaggtg
    18121 attgttgaaa aagaggaaaa aggagaagaa atgaaaccag taatttccat catcatgggt
    18181 tcaaaatccg actgggcaac catgcaaaaa acagcagaag tcctagaccg cttcggtgta
    18241 gcctacgaaa agaaagttgt ttccgcacac cgtacaccag acctcatgtt caaacatgca
    18301 gaagaagccc gtagtcgtgg catcaagatc atcatcgcag gtgctggtgg cgcagcgcat
    18361 ttgccaggca tggtagctgc caaaacaacc cttccaatca ttggtgtgcc agtcaagtct
    18421 cgtgctctta gtggagtgga ttcactctat tctatcgttc agatgccggg tggggtgcct
    18481 gttgcgacca tggctatcgg tgaagctgga gcgactaacg cagctatctt tgccctccgt
    18541 ctcctctctg tagaagataa gtccattgcg gatgcacttg ccaactttgc tgaagaacaa
    18601 ggaaaaatcg cagaggagtc gtcaaatgag ctcatctaaa acaatcggaa ttatcggtgg
    18661 cggtcaactg ggtcagatga tggccatttc tgctatctac atgggccaca aggttatcgc
    18721 gctggatcct gcggcggatt gcccggcctc tcgcgtggcg gaaatcattg tggcacctta
    18781 taacgatgtg gacgccctcc gtcagttggc agaccgttgc gatgtcctca cttatgagtt
    18841 tgaaaatgtc gacgctgacg gtttggatgc cgttatcaag gatggacaac tccctcaagg
    18901 aacagatctg ctccgcattt cgcaaaatcg tatttttgaa aaggactttt tgtcaaacaa
    18961 ggctcaagtc actgtggcac cctacaaggt cgtgacttct agcctagact tggcagatat
    19021 cgacttgtcg aaaaactatg tcctcaagac tgcgactggt ggctacgatg gtcatggaca
    19081 aaaggttatt cgttcagaag cagacttgga agcagcctat gcgctagcag actcagcaga
    19141 ctgcgtcttg gaagaatttg tcaactttga ccttgagatt tctgtcatcg tgtcaggaaa
    19201 tggcaaggag gtgacgtttt tcccagttca ggaaaatatc caccgcaaca atatcctgtc
    19261 taagaccatc gtaccagccc gcatttctga aagtctagta gacaaggcta aagctatggc
    19321 agtgcgaatc gcagaacaac tcaacttgtc tggaactctc tgtgtggaaa tgtttgcgac
    19381 tgatgatgac gttattgtca atgaaatcgc cccacgacca cataactctg ggcactattc
    19441 tattgaagcc tgtgatttct ctcagtttga cacccatatt ctcggtgttc tcggagcacc
    19501 attaccagtc atcaaactcc atgcgcctgc cgtcatgctt aacgttctcg gccagcatgt
    19561 tgaggccgct gaaaaatatg tcacagaaaa ttcaagcgcc cacctccaca tgtatggtaa
    19621 aatagaagcg aagcacaacc gcaagatggg acatgtgact ttgattagta atgaaccaga
    19681 tagtgtggat gagcttgggg aagggattga tttttaggac aagtctatga tacaaattat
    19741 cgttaataca tttattgaaa aggataagac tggagcagtt gttgaagtgt tgtatgccag
    19801 tgctgaccaa gataaggtac aagctaaata tgaagaacta gctgcacaat accccgaaaa
    19861 ttatttagct atctatgatg taccgctgga tacggatttg aatacactag atcattaccc
    19921 gtctgtgttt attggaaaag aggagtttga gtagaaatct tggtttacct agatagctta
    19981 ttcccaacag cttaagaaga aaggaaaaat taacacatga tcaaccgtta ctctcgccct
    20041 gagatggcga atatttggag tgaagaaaat aaataccgtg cttggcttga ggtggaaatc
    20101 ctctctgacg aggcatgggc tgagttgggg gaaatcccta aggaagatgt ggctttgatt
    20161 cgcaagaagg cggactttga catcgaccgt attttggaaa ttgagcagga gacgcgccac
    20221 gatgtggtgg ctttcacgcg tgcggtttct gagactcttg gtgaagagcg caagtgggtt
    20281 cactatgggt taacttctac tgacgtggtg gatactgctt atggttacct ctacaagcag
    20341 gccaacgaca tcatccgtcg tgaccttgaa aacttcacta atatcatcgc tgacaaggcc
    20401 aaggagcaca agttcaccat catgatgggg cgtactcatg gtgtgcacgc tgagccgaca
    20461 acctttggtc ttaaattagc aacttggtac agcgaaatga aacgcaatat cgagcgcttc
    20521 gagcatgcgg ctgctggtgt agaagctggt aagatttctg gtgcggttgg gaactttgcc
    20581 aatatcccac catttgtaga ggagtatgtc tgcgataaac ttggcatccg tgcccaagaa
    20641 atctctacac aagtccttcc tcgtgacctt cacgctgagt actttgcggt tcttgccagc
    20701 attgcgactt caatcgaacg tatggcgact gagattcgtg gtctacaaaa atctgagcaa
    20761 cgcgaagtag aagagttctt tgctaaaggg caaaaagggt cttcagcaat gcctcacaaa
    20821 cgcaacccaa tcggttctga aaatatgact ggtctggcgc gtgtcattcg tggtcacatg
    20881 attacggctt atgaaaacgt cgctctctgg cacgaacgcg atatttctca ctcatcagct
    20941 gagcgtatca tcacaccaga tacgaccatt ttgattgact acatgctcaa ccgttttgga
    21001 aatatcgtca agaacttgac agtcttccca gaaaatatga tccgaaacat gaactcgact
    21061 tttggtctta tctttagcca acgggctatg ttgacattga ttgaaaaagg catgacccgt
    21121 gagcaagcct atgacttggt gcaaccaaaa acagcctact cttgggacaa ccaagtagac
    21181 tttaaaccac ttcttgaggc agattcagaa gtaacatcac gtctcacaca agaagaaatc
    21241 gatgaaatct tcaacccagt ttattacacc aaacgagtgg atgatatctt tgaacgtctt
    21301 ggactaggtg attaattaaa aaataaacag cgagcttcaa tctcgctgtt tattttttat
    21361 cgaaaagact tagtcttctt ttcttttagt gagtccatag gctgctagtg tggacatgag
    21421 tcctgcgact actagtcctg cagaatcgtg agttcctgtt tcaggaagtt ttttctctgt
    21481 taccacagga gctggatctt gaggaagagc tttgctttcc tcagcaggag cagttgatgg
    21541 agctggttgg cttgggattt ctagttttgg tttttcttca gcaatagcgg cttgtccgtt
    21601 ttcatcgcct acatgtgtta ccatagttcc gacttcgact atttgagtaa cggcttcctg
    21661 tgctacgaca ctatttacaa gtgttttcac ttccttacca tcggcagaag tgctcacaga
    21721 gtagaagttg ctacgatgtc cattgacgcc cttagtaatg acttgtgttt ttcctttgag
    21781 taagagtgga ttttcacgag tcactgtggt aaatggaatt tcttcttttt ggatatccag
    21841 tctaggtttt acctcagtag ttggtgcaag accactttca tcacccttgt gagttacagg
    21901 agcgccaact tcaaccactt ggtttataac ttctttggtt acctggctat caaggactgt
    21961 ttctgttgtt tttccatttt cagtgagtac agagatgtaa tgagttcgtt cacctttgac
    22021 tcctgctgtg ataatatttt cctgaccagc tgggaggtta ggattttctt tcttgataac
    22081 ttcaaatgga atttcttcag ttcttgtgat gagttctggt ctggtttcaa cattggcagc
    22141 cacttcattt tcatctaggc ttcctgaatg agttgcagct ggtttgaggc cttgaagagc
    22201 ggcttttagg ttggctacaa gtgtgtcaag ctcagcttgt ttattacggt tgaggttgta
    22261 atttagagct gttttagctg cgtcaagggc ctcaagactt tctttactat atccttctaa
    22321 gtttgtagga attttagcta attcttcgcg gagagcatta taattagcac ggaagtagtc
    22381 tttgttgtgg tctgcaaagg cagtcatgag ttcaaagatt tcctcttcct tgtactcagc
    22441 gcttggtcta tctgcccaga ttgaaagcat acttccaact gttggaagat ctacttcagg
    22501 atatttggta gaagctagtt gattgaatgg tgtttttcca gtattctcaa tagctttctt
    22561 gaggaaacca ccaccatctt ctggtttttg accaagaaca taataccagt caccgttggt
    22621 attcaagaac ttataaccct tgcttgctag gtattgaggt gatgcgaggt tgtatcccca
    22681 ccagccttta gaccagtaag aaatcaagac atctttgtca aactgaacat cgtccttgtc
    22741 ttcatagtag aagccatcgt tgaaggccat tggttgaagc cctctttctt tggccatagc
    22801 tgcgagggtg ttggcatatt cggcaaattt gccatagagt tgataccact tgaggtagta
    22861 ccagccttgg gcactagtcg catcgttggc gtattcgtca gtaccaaagt tgaaaatctt
    22921 tgttttacct gcaaagaagt ccatgtattt accgatgagg gcttttacaa agttcatcgc
    22981 ttcttcgttt ttcaagtcca tagttgtttt tgaaacttta tcaaagtggg cttgaggatt
    23041 tttaatacct aatttttcca tggcaaccag catagcatcc atgtgacctg gactgttaat
    23101 agctgggatg agaccgatgt ccttagattt agcgtattca attagctctg ttacttctgc
    23161 ctgtgttagt gcagtaccgt ttggatcgtc gtagtaagct ttagttcctt cgataatagc
    23221 ttttttaacg tcatcactag cataggtttt tccgttggca gtaatggtca tatcatcgag
    23281 tagaaagcga agtccgtcat ttcctagaag gagatggaca tcagaatatc cgagatcact
    23341 ggccttgtct acgatgcgtt tgagttggtc cagagtaaag tatttgcgtc cagcatcgat
    23401 tgagattacc ttgtttttgg caagtttttc aacctcacgt ttagcttctt cttctttttg
    23461 agcttcaggc gtgagggtca agttgttgac agtttcttga agtttagcaa tggcttgatc
    23521 aatcgtatct tgttgggcac ggctaaggtt gctatcgaga gagcgaatag ctttttcagc
    23581 ttcttttacg gccgtgacgc tttctgcagt ataacggttc aggtcttttg gtacctcgtt
    23641 aagtgcttgc tctgcagatt cataatcagc tgcgaagtat tcagcgttgg catttgcaaa
    23701 atgacgcatg agtttgaaga ggcgtgatgg tgaataacgt gcagatggag tgtcagtcca
    23761 agcagctacc ataccaccga tgattgggat atcagctcct tctgtttttg gtacagaagt
    23821 gattggtgtg tttttaatac cattgagccc ctgatcgaga ttgtaccagc cttggccatc
    23881 agcgtttcgt ccaagaacgt agtaccaagc atcattggta ttaaggattt ggtgaccttt
    23941 ttcagctagt agtttagaag aagcgacatc gtagcctccc caaccaccag tccacataga
    24001 aacgatgatg tctttgtcaa aactaccaaa gcttgtgtcg ctattgtagt agataccgtc
    24061 gttaaaggcc attggtttga gaccgtgcga ttttacaata cgagcgaggt cattggcgta
    24121 ggcaataaat ttttcatagc cttttacagg gtagccttcg tttggatagt atttatcagc
    24181 ttgaagcaca ctccaacctt tagcatctgt cgcatcattg gcatattcat caagtccgat
    24241 gttgaagatt tcagtctttt tcgcgaaata agcagcatac ttgtcgataa gggcttttgt
    24301 aaaagcgaca gcttgttcgt tgtcaagatt gacagtacgg gctgattcct tcccaaaata
    24361 gctaaagtta gggttttgga ttcccaattc tttcatggca ttgagaatcg catccatgtg
    24421 accaggacta tttactgtcg gaatgagacc gataccttta tctttggcat agttaatcag
    24481 atctgtcatt tgactttctg ttaagtgatt gccgtttgga tcgttgtaat aatcatttgt
    24541 acctttttca atggcgcgtt tgacatcgtc actggcatag gtcttgccgt tagctgtgat
    24601 gctcatatcg tccaacatga aacggagtcc atcatttccg actaataggt gtaaatcagt
    24661 gtagccataa tgtttcgctt tatcgatgat ttccttgagc tgttctggtg agaaatattt
    24721 acgtccagca tcaatagaaa caattttctt tttcgctagt ttttcattta cagttgcagc
    24781 acgttccttt cctgcctctg tttccggttt gtcagcctct gctttcgctt catctttttt
    24841 agctggttta tccttgtcag tcttgtctgt atttgactct ttagaatcaa cctctttcgc
    24901 ttcttccttt ttagggctag cttcttctgc ctttttatta gcagtttctt tttcagcaga
    24961 agttggagtt accacctctg ctttatcact aggagttgaa ctaacttcct cttgtggttt
    25021 ttcttctgtt tttggaagac tagctacctt atcagtagct ggagtttctg tttctacagt
    25081 ttttggagct tctggttgaa gctctgcttt aggtgtttcc tcagtccgat tttcggatga
    25141 ttgaggggaa tcagaaaccg tatggatggt cggttggttt tctgtagtag taggagtaac
    25201 tccatcggct gcaacagtct gtgcttggaa ggcaaatcca attagaacag aagctgctcc
    25261 tacagcgtat ttacgaatag aaaaacgctg ttgtttttca tgtttcattg caaaacctcc
    25321 tgattgcatt gttatattga tagcgattat ataaatcaac gcctttattt tatttcttat
    25381 attaacgaga gtcaagagga gatgacaaaa aactataata agtataaaaa aatataaaat
    25441 ttaaacttaa gatttcagat tggtcggaaa aa
//
LOCUS       DAVLIK010000028        25060 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLIK010000028 DAVLIK010000000
VERSION     DAVLIK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.028"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            385..732
                     /gene="ssrA"
                     /locus_tag="VXE87_001291"
     tmRNA           385..732
                     /gene="ssrA"
                     /locus_tag="VXE87_001291"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(905..992)
                     /locus_tag="VXE87_001292"
     tRNA            complement(905..992)
                     /locus_tag="VXE87_001292"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(956..958),aa:Ser,seq:gga)
     gene            1155..1895
                     /locus_tag="VXE87_001293"
     CDS             1155..1895
                     /locus_tag="VXE87_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0842830.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            1892..2803
                     /gene="pfkB"
                     /locus_tag="VXE87_001294"
     CDS             1892..2803
                     /gene="pfkB"
                     /locus_tag="VXE87_001294"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0842831.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSDGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            2800..4752
                     /locus_tag="VXE87_001295"
     CDS             2800..4752
                     /locus_tag="VXE87_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0842832.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            4916..7141
                     /locus_tag="VXE87_001296"
     CDS             4916..7141
                     /locus_tag="VXE87_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0842833.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(7186..7614)
                     /locus_tag="VXE87_001297"
     CDS             complement(7186..7614)
                     /locus_tag="VXE87_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842834.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            7752..8894
                     /locus_tag="VXE87_001298"
     CDS             7752..8894
                     /locus_tag="VXE87_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0842835.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHSLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            8903..10117
                     /gene="thiI"
                     /locus_tag="VXE87_001299"
     CDS             8903..10117
                     /gene="thiI"
                     /locus_tag="VXE87_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0842836.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            10252..11076
                     /locus_tag="VXE87_001300"
     CDS             10252..11076
                     /locus_tag="VXE87_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0842837.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            11089..12255
                     /locus_tag="VXE87_001301"
     CDS             11089..12255
                     /locus_tag="VXE87_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0842838.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            12763..14256
                     /locus_tag="VXE87_001302"
     CDS             12763..14256
                     /locus_tag="VXE87_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0842839.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            14269..14811
                     /locus_tag="VXE87_001303"
     CDS             14269..14811
                     /locus_tag="VXE87_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0842840.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRYSEEVVA"
     gene            14808..15863
                     /locus_tag="VXE87_001304"
     CDS             14808..15863
                     /locus_tag="VXE87_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0842841.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGREIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIYG
                     SGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYLF
                     YFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVVQVDKSQLAIQKS
                     LEELETLKKSLMQEYFG"
     gene            15923..16159
                     /locus_tag="VXE87_001305"
     CDS             15923..16159
                     /locus_tag="VXE87_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0842842.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            16156..16569
                     /locus_tag="VXE87_001306"
     CDS             16156..16569
                     /locus_tag="VXE87_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0842843.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            16687..17652
                     /locus_tag="VXE87_001307"
     CDS             16687..17652
                     /locus_tag="VXE87_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0842844.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            17675..18256
                     /locus_tag="VXE87_001308"
     CDS             17675..18256
                     /locus_tag="VXE87_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0842845.1"
                     /translation="MFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTK
                     NVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRI
                     NSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQ
                     NEFADFVAQVDKSQFACEIAIKVWRNSLKFSII"
     gene            18286..21636
                     /locus_tag="VXE87_001309"
     CDS             18286..21636
                     /locus_tag="VXE87_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0842846.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(22142..22612)
                     /locus_tag="VXE87_001310"
     CDS             complement(22142..22612)
                     /locus_tag="VXE87_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0842847.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(22629..24902)
                     /locus_tag="VXE87_001311"
     CDS             complement(22629..24902)
                     /locus_tag="VXE87_001311"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0842848.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         7804 a         4373 c         5407 g         7476 t
ORIGIN      
        1 tttgactgtc ctgatctatt cgtcctattc ttatttcatt ttactatatt ttggtgcaat
       61 aagtgaaaag tagtccgaat aatataagga ttgattttat agtttttaaa ctcaaatgaa
      121 ttaaaataaa gagagtacga aaattctcat ctgaaagtat tttagaataa ttctcttcgt
      181 gaatttcttc aaaacagata gcttcatctt aggtatgtgt taattggatt tcgtaagctc
      241 tatttacaat cgtaaagtta tgcactgaaa aagttgtagt tagtcttcca gtttgctaaa
      301 tttctcgaat agtatctttt ttaggtatgt gatttctttt tgcatttttg agttagataa
      361 ggtataatgg ttttattgtc ttttggggtc gttacggatt cgacaggcat tatgaggcat
      421 attttgcgac tcgtgtggcg acgtaaacgc tcagttaaat ataactgcaa aaaataacac
      481 ttcttacgct ctagctgcct aaaaaccagc aggcgtgacc cgatttggat tgctcgtgtt
      541 caatgacagg tcttattatt agcgagatac gattaagcct tgtctagcgg tttgataaga
      601 gattgataga ctcgcagttt ctagacttga gttatgtgtc gaggggctgt taaaataata
      661 cataacctat ggttgtagac aaatatgttg gcaggtgttt ggacgtgggt tcgactccca
      721 ccggctccat tattcctttg cattccttgg taaaacgttg ttaaatcaac gttttttatt
      781 tttatctttg gtattccttt gcattctttt gctaaaaagg gagtcacaaa cagaccctat
      841 tttaaaaaaa ggatagaaaa aaggatacaa catttgtcgc atcctaaaaa taatcttttt
      901 tcgacggaag acatgggatt cgaacccacg cacgctatta cacgcctacc gcgtttccaa
      961 cacggcctct taagcctctt gagtaatctt ccaatactta ctcaaatagt ctaccataaa
     1021 ggctcttatc ttgcaataaa aattctagaa ataagaaaaa atgatagatt ttgaaagaaa
     1081 atgataaaaa atgcttgact tcgaaagaaa gtatggtaga atgaatagtg taaacgataa
     1141 caggaggtga ttcagtgtta aaaacagaac gtaaacaact gattttagag gagttaaatc
     1201 aacatcatgt agtttctcta gaaaaattag ttagtttgct agaaacgtca gaatcaacgg
     1261 ttcgaagaga cttggatgag ttggaagcgg aaaacaagct tcgtcgtgtg catggtggag
     1321 cagaactccc ccactcctta caggaagaag aaaccattca agaaaaatct gtcaaaaacc
     1381 ttcaagaaaa gaagttgctg gctcagaaag cagcctctct cattaaagaa aaagatgtca
     1441 tctttatcga tgctggaaca acaactgctt ttttgattca tgaattggtc aataagaatg
     1501 ttacagttgt gaccaactcc attcaccatg ccgctcagtt ggttgaaaag cagattccaa
     1561 ctgtcatggt tggaggaaac gtcaagacgg cgacagatgc tagtatcggt ggcgttgctc
     1621 ttaaccagat taaccaattg cactttgacc gtgcctttat cggaatgaat ggtgttgacg
     1681 atggctatta tacgactcct gatatggagg agggagctgt gaaaagagct attttggaga
     1741 atgccaagca gacctacgtc ttggtggatt cgtcaaaaat tggacaaact tgctttgcca
     1801 aggtagcacc actcaaacgc gctatcgtta tcactagtca agggcatgag ctcttgcagg
     1861 ttattaagga gaaaacggag gtaatagaag tatgatttat acagtcacac tcaatccatc
     1921 cattgactat atcgttcgtt tggaccaagt caaagttggt agtgtaaatc gtatggacag
     1981 tgatgataag tttgctggtg ggaaaggaat caatgtcagc cgtgtcttga aacgtttgaa
     2041 tataccaaat acagcgacgg gatttatcgg tggctttact ggtaaattta tcacagatac
     2101 tttagcagag gaagaaatcg agacacgttt tgtccaggtg gcagaagata ctcgtatcaa
     2161 tgttaaaatc aaagcagacc aagaaacaga aatcaacgga acgggtccaa ctgttgaatc
     2221 ggttcagcta gaagaattga aagctatttt atctagtctg acagcagaag atacagttgt
     2281 ctttgcaggt tcaagtgcta aaaatctagg caatgttatc tataaggatt tgatttcctt
     2341 gacgcgccag actggtgcgc aagtggtctg tgactttgaa ggacagacct taattgatag
     2401 tttggactac cagcctcttc ttgtaaaacc aaacaatcat gaacttggag cgatttttgg
     2461 ggttaaactc gaaagtttag atgaaattga gaaatacgct cgtgagttac tggctaaggg
     2521 tgctcaaaat gttattatct ctatggctgg tgatggtgcc cttcttgtca catctgatgg
     2581 agcttacttc gctaaaccaa tcaagggaac agtcaaaaat tcagttggag ctggtgattc
     2641 tatggttgct ggattcacag gtgaatttgt caaatcaaaa gacgcagtag aagccttcaa
     2701 atggggagtg gcttgcggaa cggcaactac cttctcagat gacttggcaa cggcggaatt
     2761 tattaaagaa acatatggaa aagttgaggt agaaaaacga tgaaaattca agacctattg
     2821 agaaaagatg tcatgttgct agatttgcag gcaactgaaa aaacagctgt catcgacgag
     2881 atgattaaaa atttgacaga ccacggttat gtaacagatt ttgaaacatt taaagaagga
     2941 attttggcgc gtgaagcttt gacttctact ggtttgggtg atggaatcgc aatgcctcac
     3001 agcaaaaacg ctgctgtcaa agaagcgaca gttctatttg ctaagtcaaa taagggtgtt
     3061 gactacgaga gcttggatgg acaagcaact gacctcttct tcatgattgc agctccagaa
     3121 ggtgccaatg atactcactt ggcagccttg gcagaattgt ctcaatactt gatgaaagac
     3181 ggttttgcag acaaacttcg tcaagcaaca tctgcagacc aagttatcga actttttgac
     3241 caagcttcag aaaaaactga ggaacttgtt caagcacctg ctaatgactc tggtgacttt
     3301 atcgtagctg ttacagcttg tacaacaggt attgcccaca cttacatggc ccaagaagcc
     3361 cttcaaaaag tagctgctga aatgggggtt ggtatcaagg tcgaaaccaa cggtgctagc
     3421 ggtgttggaa atcaactaac tgcagaagat atccgtaagg ctaaagctat tatcattgca
     3481 gcagacaagg ccgttgaaat ggatcgattt gatggaaaac cattgatcaa tcgtccagtt
     3541 gctgacggta tccgtaagac agaagagcta attaacttgg ctctttcagg agatactgaa
     3601 gtctaccgtg ccgctaatgg tgccaaagct gcaacagcct ctaacgaaaa acaaagcctt
     3661 ggtggtgcct tgtacaaaca cttgatgagt ggtgtatctc aaatgttacc attcgttatc
     3721 ggtggtggta tcatgattgc ccttgccttc ttgattgacg gtgctttggg tgttccaaat
     3781 gaaaaccttg gcaatcttgg ttcttaccat gagttagctt ctatgttcat gaaaattggt
     3841 ggagctgcct ttggtttgat gcttccagtc tttgcgggtt atgttgccta ctctattgct
     3901 gaaaaaccgg gtttggtagc aggtttcgtg gctggtgcta ttgccaaaga aggttttgcc
     3961 tttggtaaaa ttccttatgc cgcaggtggt gaagcaactt caactcttgc aggtgtctca
     4021 tctggtttcc taggtgccct tgttggtgga tttatcgcag gtgccttggt tcttgccatc
     4081 aagaaatacg ttaaagttcc tcgttcactc gaaggtgcta aatcaatcct tctattgcca
     4141 cttcttggaa caatcttgac aggatttgtt atgctagctg tgaatatccc aatggctgca
     4201 atcaacactg ctatgaatga cttcctaggc ggtcttggag gaggttcagc tgtccttctt
     4261 ggtatcgtcc ttggtggaat gatggctgtt gacatgggtg gaccagttaa taaagcagct
     4321 tatgtctttg gtacaggtac gcttgcagca actgtttctt caggtggttc tgtagccatg
     4381 gcagcagtta tggctggagg aatggtgcca ccacttgcaa tctttgtcgc aactcttctt
     4441 ttcaaagata aatttactaa ggaagaacgt aactctggtt tgacaaacat catcatgggc
     4501 ttgtcattta tcactgaggg agcgattcca tttggtgccg ctgacccagc tcgtgcgatt
     4561 ccaagcttca tccttggttc agcagtagca ggtggactcg ttggtcttac tggtatcaaa
     4621 ctcatggcgc cacacggagg aatcttcgtt atcgccctta cttcaaatgc tctcctttac
     4681 ctcgtttctg tcttggtagg agcaatcgta agtggtgtgg tttatggtta cctacgcaaa
     4741 ccacaagcat aaaaaataga aaaatgaaaa gattggaccg tttggtgcag tctttttctc
     4801 ttcccgaaat gcctgtgaaa tatggtataa tagaagaatg gcaaacaaga atacaagtac
     4861 aacaagacgg agaccgtcta aagcagaact ggaaagaaaa gaagcgattc aacgaatgtt
     4921 gatttcgtta ggaattgcga ttttattgat tttcgcagcc ttcaaattag gggctgcagg
     4981 tataaccctt tataatttaa ttcgcttgct agtgggtagc ctagcttatc tggcgatatt
     5041 cggcctatta atctatctct tctttttcaa gtggatacga aaacaggaag gactcttatc
     5101 tggctttttc accatatttg ctggcttact cttgattttt gaggcctact tggtttggaa
     5161 atatggtttg gacaagtccg ttctaaaagg gaccatggct caggttgtga cagatctgac
     5221 tggttttcga acgactagct ttgctggagg gggcttgatc ggggtcgctc tttatattcc
     5281 aacagccttt ctcttttcaa atatcggaac ttactttatt ggttctatct tgattttagt
     5341 gggttctctc ctagtcagcc cttggtctgt ttacgatatt gctgaatttt tcagtagagg
     5401 ctttgccaaa tggtgggaag ggcacgagcg tcgaaaagag gaacgctttg tcaaacaaga
     5461 agaaaaagct cgccaaaagg ctgagaaaga ggctagatta gaacaagaag agactgaaaa
     5521 agccttactc gatttgcctc ctgttgatat ggaaacgggt gaaattctga cagaggaagc
     5581 tgttcaaaat cttccaccta ttccagaaga aaagtgggtg gaaccagaaa tcatcctgcc
     5641 tcaagctgaa cttaaattcc ctgaacagga agatgactca gatgacgaag atgttcaggt
     5701 cgatttttca gccaaagaag cccttgaata caaacttcca agcttacaac tctttgcacc
     5761 agataaacca aaagatcagt ctaaagagaa gaaaattgtc agagaaaata tcaaaatctt
     5821 agaagcaacc tttgctagct ttggtattaa ggtaacagtt gaacgggccg aaattgggcc
     5881 atcagtgacc aagtatgaag tcaagccggc tgttggtgta agggtcaacc gcatttccaa
     5941 tctatcagat gacctcgctc tagccttggc tgccaaagat gtccggattg aagcaccaat
     6001 ccctgggaaa tccctaatcg gaattgaagt gcccaactcc gatattgcca ctgtatcttt
     6061 ccgagaacta tgggaacaat cgcaaacgaa agcagaaaat ttcttggaaa ttcctttagg
     6121 gaaggctgtt aatggaaccg caagagcttt tgacctttct aaaatgcccc acttgctagt
     6181 tgcaggttca acgggttcag ggaagtcagt agcagttaac ggcattattg ctagcattct
     6241 catgaaggcg agaccagatc aagttaaatt tatgatggtc gatcccaaga tggttgagtt
     6301 atctgtttac aatgatattc cccacctctt gattccagtc gtgaccaatc cacgcaaagc
     6361 cagcaaggct ctgcaaaagg ttgtggatga aatggaaaac cgttatgaac tctttgccaa
     6421 ggtgggagtt cggaatattg caggttttaa tgccaaggta gaagagttca attcccagtc
     6481 tgagtacaag caaattccgc taccattcat tgtcgtgatt gtggatgagt tggctgacct
     6541 catgatggtg gccagcaagg aagtggaaga tgctatcatc cgtcttgggc agaaggcgcg
     6601 tgctgcaggt atccacatga ttcttgcaac tcagcgtcca tctgttgatg tcatctctgg
     6661 tttgattaag gccaatgttc catctcgtgt agcatttgcg gtttcatcag gaacagactc
     6721 ccgtacgatt ttggatgaaa atggagcaga aaaacttctt ggtcgaggag acatgctctt
     6781 taaaccgatt gatgaaaatc atccagttcg tctccaaggc tcctttatct cggatgacga
     6841 tgttgagcgc attgtgaact tcatcaaggc tcaggcagat gcagactacg atgagagttt
     6901 tgatccaggt gaggtttctg aaaatgaagg agaattttcg gatggagatg ctggtggtga
     6961 tccgcttttt gaagaagcta agtctttggt tatcgaaaca cagaaagcca gtgcatccat
     7021 gattcaacgt cgtttgtcag ttggatttaa ccgtgcgacc cgtctcatgg aagagcttga
     7081 gatggcaggt gtcattggtc cagctgaagg taccaaacca agaaaagttt tacaacaata
     7141 aaaaaatagc ttctttccaa gtttggaagg aggctatttt agtggttatt gattactttt
     7201 attttctgaa gttggagtat tgggctgttt ttcattttca gtggcaggtt tacttgtagc
     7261 aggtgtagta gagtcctgag ttgctgtttt ctgatcttct tttttctctt ccttgacgct
     7321 agattttggt gtttcctctt gctgtgtttt ttcttgacta gtgttagtct ctttagttgg
     7381 actggtgttt tccttagggg attccttttg gatttctttg acaatggttg tcgtctggct
     7441 tgtcgtaggt tcttttttaa tatttttgtt attatccaag gcgttcatga tcgtgatact
     7501 cgcggtaatc aagccaagga tactagcgat tgtagcaacg gttttttgaa agactgtaaa
     7561 gccttttttg atgtgttctg tttttggttt tgaagttcta cgatagttag acatacattc
     7621 tctcctttga ttatgattta ttatactctg tttctttaaa aaaatcttaa aaaaagagaa
     7681 attgcccttt cttgtcgcaa gctccgtttc atgatacaat agaggaagtg attttagaaa
     7741 gcgtgagaaa catgatttac tttgataatt cagcgacgac caagccttat cctgaagccc
     7801 ttgaaaccta tatgcaggtc gcttcaaaaa ttttaggaaa cccatctagt ctccatagtt
     7861 tgggagacca agcaacacga atcttagatg cttctcgcca acagattgca gatttaatcg
     7921 gtaagaaaag cgatgaaatc ttctttacct ctggtggaac agaaggggat aactgggtta
     7981 tcaagggtgt ggcctttgaa aaagctcagt ttggcaagca catcattgtt tcagccattg
     8041 aacatccagc agtcaaagag tcagccctct ggttgaaaag tcaaggattt gaagtggatt
     8101 ttgctccagt tgataacaaa ggatttgtgg atgttgaggc gctagaagat ttgataagac
     8161 ctgatacgac cctcgtttcc atcatggctg tgaacaatga aatcggctct atccaaccta
     8221 ttgaggctat ttcagaattc ttggcagaca agccaactat ttccttccac gttgatgcgg
     8281 ttcaggcgct tgccaagatt ccgactgaaa agtatctgac agaacgagtg gatttcgcga
     8341 ctttctctgg tcacaagttc cacggaatcc gtggtgttgg ttttatctat atcaagtctg
     8401 gcaagaagat tacgcctctt ttaacaggtg gtggtcagga acgtgattac cgttcgacaa
     8461 ctgaaaatgt ggcaggaatt gcagcgaccg ctaaggctct ccgtttatct atggaaaagc
     8521 tagatatctt taggagcaag actgggcaga tgaaggcagt gattcgtcaa gcacttctgg
     8581 actatccgga tatatttgtc ttttcagatg aggaagactt cgcccctcat attctgactt
     8641 ttggaatcaa gggtgttcgt ggtgaggtca ttgttcacgc ctttgaagac tatgatattt
     8701 tcatctcaac gacctcggct tgttcgtcca aggctgggaa accagccgga accctgattg
     8761 ctatgggagt ggacaaggat aaggctcagt cagctgtgcg tcttagtcta gaccttgaaa
     8821 atgatatgag tcaggtcgag cagttcttga ccaagctaaa attaatttac aatcaaacta
     8881 gaaaagtaag ataggagcat tcatgcagta ttcagaaatt atgattcgct acggtgagct
     8941 gtcaaccaag ggcaaaaatc gtatgcgttt catcaataaa cttcgcaata atatttcaga
     9001 cgttttgtct atctatcccc aagttaaggt aacagcagat cgcgaccgtg cccacgctta
     9061 cctcaatgga gcagattaca cagcagtagc agaatcgctc aaacaagtat ttggaattca
     9121 aaacttttcc cctgtttata aggttgaaaa atctgtagaa gttctgaagt ctgctgtcca
     9181 agagattatg caggacatct acaaggaagg catgaccttt aaaatctcta gcaagcgtag
     9241 cgaccacacc tttgaattgg acagtcgtga actcaaccaa acgcttggag gggctgtatt
     9301 cgaagccatt ccaaacgtac aagctcaaat gaaaagtcct gacatcaatc ttcaggtgga
     9361 gatacgtgaa gaagcagcct atctttctta tgaaaccgtt cgaggggcag gtggattacc
     9421 agtgggaact tctggtaagg gcatgctcat gttgtcaggg ggaatcgatt cccctgtagc
     9481 tggctatcta gcgcttaaac gaggggtaga tatagaggca gttcactttg ccagcccacc
     9541 ttacacgagt cctggtgctc ttaaaaaagc ccaagatttg acccgtaaat taaccaaatt
     9601 tgggggaaat atccagttta tcgaagttcc ttttacagag attcaagagg aaatcaaagc
     9661 caaagcgcca gaagcctacc ttatgacctt gacgcgtcgt tttatgatgc gtattactga
     9721 ccgtattcgt gaggtacgaa atggtttagt tatcatcaat ggggaaagtc taggtcaagt
     9781 agccagccaa acccttgaaa gtatgaaggc tatcaatgct gttaccaaca ctcccatcat
     9841 tcgtcctgtg gttaccatgg acaagttgga aatcattgac atcgcccagg aaatcgatac
     9901 ctttgacatt tcaatccaac cgtttgaaga ctgttgtacc atttttgcac cagatcgtcc
     9961 aaaaacaaat cctaaaatta agaatgcgga gcagtacgaa gcgcgtatgg atgttgaagg
    10021 cttggttgag cgagcagtgg ctggaatcat gattactgaa atcacacctc aagccgaaaa
    10081 agatgaagtt gatgacttga ttgacaatct gctctaattc agaaaatcca aaagaatagc
    10141 gaaaatcagt aaaaaaagtt agttttttct ctaaaaacag gtaaaaaact aacttttttt
    10201 atttttatga tataatgata taaaattttg aatatagaga gttttctgac aatgaatcaa
    10261 tcctactttt atctaaaaat gaaagaacac aaactcaagg ttccttatac aggtaaggag
    10321 cgccgtgtac gtattcttct tcctaaagat tatgagaaag atacagaccg ttcctatcct
    10381 gttgtatact ttcatgacgg gcaaaatgtt tttaatagca aagagtcttt cattggacat
    10441 tcatggaaga ttatcccagc tatcaaacga aatccggata tcagtcgcat gattgtcgtt
    10501 gctattgaca atgatggtat ggggcggatg aatgagtatg cggcttggaa gttccaagaa
    10561 tctcctatcc cagagcagca gtttggtggt aagggtgtgg agtatgctga gtttgtcatg
    10621 gaggtggtca agccttttat caagcacaaa acaggttggt ttgatggcat gatgacgaca
    10681 ggttgctcta tgggagccta tcatgcactc aatttcttcc tccagcatcc agatgtcttt
    10741 accaaagtga ttgctctcag tggtgtttac gacgcacgtt tctttgtcgg tgattactac
    10801 aacgatgatg ctatttacca aaactcgcca gtagattata tttggaacca aaacgatggc
    10861 tggtttattg accgttaccg tcaggcagag attgtgctgt gtacggggct tggagcctgg
    10921 gaacaagatg gtttaccatc cttttacaag ctcaaagaag cctttgacca gaaacaaatt
    10981 ccagcctggt ttgctgaatg gggacatgat gtcgcccacg actgggaatg gtggcgtaaa
    11041 caaatgcctt atttcctcgg taatctctat ttataaaagg agttacctat gaattacctt
    11101 gttatttctc cctactatcc acaaaacttt caacagttta ccatcgaact agctaataaa
    11161 ggcatcacag tcttgggaat tggtcaagag tcttacgagc aattggatga gcccttgcgc
    11221 aatagcttga ccgagtattt tcgtgttgat aatcttgaga acatagatga agtcaaacgt
    11281 gcagttgctt ttctctttta taaacatggt ccaattgacc gcatcgagtc tcacaatgaa
    11341 tactggcttg agctagacgc aacactcaga gaacaattca atgtttttgg tgccaaacca
    11401 gaggatctca aaaagacgaa atataagtct gaaatgaaga aacttttcaa aaaagcaggt
    11461 gttcctgtgg tacctggagc tgttatcaag acggaagcag atgttgatca agcagtgaaa
    11521 gaaatcggtc ttccaatgat tgccaaacct gataatggag tgggagcagc cgcaaccttt
    11581 aaacttgaga cagaagacga tatcaatcac ttcaagcaag aatgggacca ttcaaccctt
    11641 tatttctttg aaaaatttgt cacttccagc gaaatctgta cctttgacgg gctcgtggac
    11701 aaggatggaa agattgtctt ctcaacaacc tttgactacg cctatacacc gcttgacctc
    11761 atgatttata agatggacaa ttcttattat gtgctcaagg atatggatcc taaactgcgc
    11821 aagtatgggg aagcaattgt caaagaattt ggtatgaaag aacggttttt ccatattgag
    11881 ttcttccgtg agggggacga ttatattacc atcgagtaca ataaccgccc tgcaggtggt
    11941 tttaccattg atgtttataa ctttgctcat tccttggacc tttatcgtgg ctatgcagct
    12001 attgtcgcag gagaggagtt cccggcgtca gactttgaaa ctcagtattg tttggctact
    12061 tctcgccgtg caaatgctca ctatgtttat tcagaagagg atttgcttgc caaatatagc
    12121 cagcagttca aggttaaaaa agtcatgcca gctgccttcg cggaacttca aggagattac
    12181 ctgtatatgc tgacaactcc gagtcgacaa gaaatggatc agatgattgc tgatttcgga
    12241 caacgtcaag aataagaact atcggattaa ggaaattcac tcccttaatc cttttgtttt
    12301 gtctggtaaa aaataagagc atcctaacaa ggtagctatc ataaaacttg ttcgataact
    12361 atttgaagca ggattaggtg gctagaaatt gaattttaac atttcaattt agtcatagta
    12421 ttgtgttttc gtatccttaa atcagctaaa aggatccatg acgacaccta tacgatatag
    12481 ttttcaagat accaaacaag tctattaata ttcaatgaaa atcaaagagc aaactaggaa
    12541 gctagccgca ggtttctcaa aacactgttt tgaggttgtg gatagaactg acagagtcag
    12601 tatcatatac ctacggcaag gtgaagctga cgtggtttga agagattttc gaagagtata
    12661 aaatattcag gtgacgcata gatatagtta attgaagctt tgtttgaaat ctgataaaat
    12721 aatgatatta ctaagtttta aaaactaaag aaaagggaag atatgattac aggcgaatta
    12781 aaaaataaaa tcgatcagct gtgggaaatt ctttggacag aaggaaacgc aaatccttta
    12841 acaaatattg aacagttgac ttatctctta tttatgaaag atttggatag tgtcgagctt
    12901 ggacgtgaaa gtgatgctga atttctaggg attccttatg agggagtttt tccaaaagat
    12961 aaacctgaat accgttggtc aacttttaaa aatataggag atgctcagga agtttatcgt
    13021 ttaatgactc aggagatttt tccgtttatt aaaaatctca agggggatac agatgataca
    13081 gccttttcac gatatatgcg agaagctatt tttcaaataa ataaacctgc tacgcttcaa
    13141 aaggcaattt ctatcttaga tgtttttcca actaggggat tagatgtaga ttttgataat
    13201 gacaaacaaa gtattactga tatcggagat atctatgaat atctgttatc aaaattgtcg
    13261 accgcaggta aaaatggaca gttccgtaca cctcgtcaca tcatcgatat gatggttgag
    13321 ttgatgcaac cgactatcaa agatatcatc tcagatcccg ctatgggttc tgctggcttc
    13381 ttagtatctg ctagccgtta cttaaagcgt aagaaagatg aatgggaaac caatacagat
    13441 aatatcaatc attttcataa tcagatgttt catggaaatg atacggatac gactatgttg
    13501 agacttgggg cgatgaacat gatgctacat ggagtagaaa atccacaaat cagttacctt
    13561 gactcgctgt ctcaagataa tgaagaagcc gataaatata ctttggtttt agcaaatcct
    13621 ccttttaagg gctcacttga ctacaattca acctctaatg accttcttgc aaccgtaaaa
    13681 accaaaaaaa cagaattact ctttctttct cttttcttgc gaactttaaa accaggtgga
    13741 cgagcagcag ttatcgtacc tgatggtgtc ctttttggtt cgtctaaagc tcataaagga
    13801 attcgtcagg aaattgtaga gaatcataag cttgatgctg taatctcaat gcctagtggt
    13861 gtgttcaagc cttatgctgg agtttcaact gccattctca tctttacaaa aactggtaat
    13921 ggtggtactg acaaagtctg gttttacgat atgaaagcgg atggtttaag tttggatgat
    13981 aagcgacaac cgattagcga caatgatatt ccagatatta tcgaacgctt tcatcatctt
    14041 gaaaaagaag cagaacgtca gagaacggat caatctttct ttgttccagt tgctgagata
    14101 aaggaaaatg attatgattt gtctatcaat aaatataaag agattgagta tgaaaaagtt
    14161 gagtatgaac caacagaggt catcttaaag aaaatcaatg atttagaaaa agaaattcaa
    14221 gctggcttgg ctgaattaga aaaattactc aagtagagag gtggctgtat gaaaaaagtg
    14281 aagttggggg aagtcttatc tctaaaaaaa ggcaagaaag ccactgtact tgctgaacaa
    14341 acaactctaa gccaacgtta tattcaaata gatgatttaa gaaataataa taatttaaaa
    14401 ttcactgaaa gtttaaatat gactgaagca ctcccagatg atattctgat agcatgggat
    14461 ggagctaatg caggaacagt tggttatgga ttatcgggag ctgttggtag tacaattacg
    14521 gtcttaaaaa agaatgagcg atacaaagaa aaaattatat cagattactt gggagtcttt
    14581 ttggaaagta aatcgcagta tttacgagaa cattcaacag gtgcaacaat tcctcattta
    14641 aacaagaata tattacttga tttacaatta gaattgctag gtatcgaaga acaagagaac
    14701 attatctgta ttcttaatac gattaaaagg cttattacta aaagaaaatt gcagttagat
    14761 gaactaaact tgctcgtcaa atcccgatat tccgaggagg tggttgcatg aagaaagtga
    14821 aattagggga agtggctact tttatcaatg gctatgcttt taaacctcaa gattggtcat
    14881 ctgaagggag agagattatc agaatacaga atctgactaa aacttcaaca gagataaatt
    14941 attattcggg tacgattgat aaaaaataca ttgttgaagc tggtgatatc cttatttcgt
    15001 ggtcgggtac attaggggtt tttcagtggt gtggaagatc cgcagtatta aatcagcaca
    15061 tttttaaagt ggtttttgat aagatagata tagataaatc gtattttaaa tatgttgttg
    15121 aaaaaggttt acaagatgct gtaaaacata ctcatggttc cacaatgaaa catttaacta
    15181 aaaaatattt tgataatatt atagttccat atacaaattt gggagagcaa caaagaattg
    15241 caagtgagct ggatttgtta agcaagctga ttttaaggag acaagaacaa cttgaagagc
    15301 ttaatctact tgtaaaatcc cgatttaacg agatgtttgg ggatgttatt ctaaatgaaa
    15361 aagaatggaa agttagcaaa tggaacgaga ttctaacaat aagaaatggt aaaaatcaaa
    15421 aacaggttga agatgctgat gggaaatttc ctatttatgg aagtggggga attatgggat
    15481 atgctaaaga ttggatagtg aagaaaaatt cagttattat tggacgtaaa ggaaatataa
    15541 ataaacctat tttagttaga gaaaattttt ggaatgtaga tacagcattt ggattagagc
    15601 ctgttttaga aaaaataaac tcagaatatt tattctattt ttgtcaatta tacaattttg
    15661 agaagttaaa taaggctgta acaataccta gtttaactaa atcagattta ttaaatattt
    15721 ccatccccct ccccccacta gccctccaaa atgagttcgc agactttgta gtccaggtcg
    15781 acaaatcaca attggcaatc caaaaatctc tggaagaact tgaaactttg aagaaatctc
    15841 tgatgcagga gtattttggc tgatattctg ccattgtaat tacggtaatg atttgttata
    15901 atacttcaaa ggaggaaatc agatggtagt aaaaacaaga aaacaaggaa attcaatcac
    15961 cattacgatt ccaagtgaat ttaatattcc aagtggtgtt aaatacgaag cgaaattgtt
    16021 accaagtggt gagattatct ttactcctga agaattgggg cagcaggttt cttatgtatc
    16081 tgatgatgcc tttgacttaa atttagataa aatatttgac gaatacgacg atgttttcaa
    16141 agctttggtg gaaaaatgac aatctatctg acagaaaagc aaattgaaaa aataaatgct
    16201 ttagcaattc aacggtattc tccaaatgag aaaattcaaa cagttagttc ttctgcctta
    16261 aatatgattg tgaacttacc agaacaattt gtctttggga agtctcttta tccaacaatt
    16321 tttgataaag caacgatact atttgtccaa ttgataaaga agcatgtttt tgctaatgct
    16381 aataaaagaa ctgctttctt cgttttggtc aaatttttac aattaaacgg ctatcgtttt
    16441 tctgtaacgg tagaagaagc agtaaaaatg tgtgtaacca tcgcagtaga agctttaact
    16501 gatgaaaaaa tgacaagcta ctccaaatgg gtttctgaac attctgttag agaaaaggtc
    16561 aaaaagtaac ctagtatgct ggatttgaat gagcacaaga aaataaatga acagacaata
    16621 ttagaattct gtaatgcaga aactgatatt gtctcttttt attgatgaat aagaaagtga
    16681 gaaattatgg aatcaaaagt tacaattatc atgcaagaaa tgttacctct tttaaataat
    16741 gaacaattac tagcgttgag agagagttta gaacatcatc tagtagacgg aaaaaagcag
    16801 cagaagtatt cgaataataa cctgttgcaa ctatttatta ccgccaagca ggtagagggc
    16861 tgtagctcaa aaacaattcg ttattaccag aggacgattg aaaacttgtt taatgctatt
    16921 aaagagtctg tgacacaact cacaacagat gatttaagga gttatttagc aaattaccag
    16981 tctgaaaagg attgtagtaa ggcaaattta gacaatatta ggcgtatatt gtcttctttt
    17041 tttgcttggc ttgagcaaga ggaatatatc attaaaaatc ccattcgacg gataaagaaa
    17101 attaagactg agcaaaatgt gaaggaaact tatactgatg aacatttgga aattatgcgt
    17161 gataactgtg aaaatttgag agatttggca ataatagacc tactagcatc gacaggtatg
    17221 cgtgtagggg agcttgtaca gttgaatcgt tcagatattg attttgaaaa cagagagtgt
    17281 gttgtctttg gtaaaggaaa gaaggagaga ccagtatatt ttgacgctcg gacgaaaatt
    17341 catttaagaa attatcttaa cgacagaaaa gatagtcacc ctgctctttt tgtaacgtta
    17401 gttggaaaag tccagaggct tggaattgct ggtgtagaga ttcgcttaag aaagttagga
    17461 gacaaactcg gtatacaaaa ggttcaccca cataagttca gaagaacttt agcgactaag
    17521 gcaattgata aaggtatgcc tatcgaacaa gtccaaaaac tgctaggtca tagcaagatt
    17581 gacacaaccc tggcctatgc catggtcaat caaaataatg tcaagcattc acaccaaaaa
    17641 ttcatctctt aaaagcaaat cccgatttaa cgagatgttt ggggaaaata aaatatttga
    17701 aagcattgat aacttatttg atattataga tggtgatagg ggcaaaaatt atcctaaatc
    17761 agatgagttg tttagtgagg agtactgttt atttttaaat acaaagaatg ttactaaaaa
    17821 cggattttca ttcgatacaa agcaatttat cactaaaaca aaggataaat tacttcgaaa
    17881 aggcaaactt gagcgttatg atatagtctt gacaacaaga ggtactgttg gaaatgtagc
    17941 gtactacgat gaattaataa aatataaaca tttacgtata aattcaggta tggtaatatt
    18001 acgtcccaag acaccaaatc taaatcagaa atttattatc catgttttaa ggaataataa
    18061 ttatagtcga gtgatatcag gaagtgctca gcctcagtta ccaattacaa aattaaaaaa
    18121 aatacttctc cccctccccc cactagccct ccaaaatgag ttcgcagact ttgtagccca
    18181 ggtcgacaaa tcacaatttg cttgtgagat agctataaaa gtgtggagaa atagcttgaa
    18241 atttagtata atatagctaa actatttgtt taaagtgaga aaaaaatggg aaattttagc
    18301 tttcttttaa aaaatgacga atatgaatct ttttcaaaac cttgcattga agctgaaaat
    18361 atgattgcta catcaactgt ggctactgcc tttatggcgc gtcgtgcttt ggagcaggct
    18421 gtccattgga tatatagtca cgattcatat ttagaagctc cctatcgtgc tactctatct
    18481 tctttagtat gggatgatga ttttagggat atcgtagatt ctgaactcca caagcagata
    18541 gttctgttga ttcggtgggg aaaccatgct gctcatggtg gtgaaattaa ggaacgagaa
    18601 gcgattttag ctttacatca tttgtatcag tttgttaatt ttatcgatta ttgttacagc
    18661 aatgaatttg tggagcgtta ttttgatgag aagtgcttac cactttcagc aaacatcaaa
    18721 taccgagaaa ctccacaatc tatgataaag ttacaagaca gtttaccaga actgcctgat
    18781 tttcatgaac agatggctgc tcagtccgta gaagttcaag agacttatac tgaaaaacgt
    18841 gagactgcag cgcaacggca agatgtgcct ttccatattg aacaattatc tgaggcagag
    18901 acaagaaagc tctttattga tatcgatctc cgtttagcag gatggatatt tgaagaaaac
    18961 tgtcgtgttg agatagccgt tgatggtctc aagcacggtt caggaattgg ttactgtgac
    19021 tacgtacttt atggtaaaaa tgggaaaatt ttagcgattg tggaggctaa aaaagcctct
    19081 gtcaatccag aagtagggga agtacaggtc aaagaatatg ctgaagcttt ggagaaacat
    19141 atcggctatc agccaatttg ctttattaca aatgggttga agcactatat acttgatggt
    19201 ccgaaccgcc gccagattgc aggcttttac tctcaagaag aattgcaatt agtgatggat
    19261 agacgtcatc ttcaaaaacc gcttgaggat atttctagta aaattaggga cgatatttcc
    19321 gggcgtcact accaaaaaca tgccattgca agcgtttgtg aagctttctc taatcatcgt
    19381 agacaggcac ttttggttat ggcaactggg gcggggaaaa ctcgtacagc agtttctcta
    19441 gttgatatct tatcacgtca taactgggta aaaaacgttc tcttcttagc cgatagaact
    19501 tccttggtta agcaagccta tgattcgttt agaaaattac tcccagatct ttccgtttgt
    19561 aacttcttag aagataaaga aggagctcaa tcaagtcgta tggtcttttc aacttatccg
    19621 accatgattg gagcgattag tggtcaagaa gaagtaaatc aacgcccttt tactgttggg
    19681 cattttgacc ttatcataat tgacgaatct caccgttcta tttatcagaa atacaagtcc
    19741 atttttgatt attttgatgc aagaattgta ggcttaacag ctactccgcg tcaagattta
    19801 gataaaaaca cctatggatt ctttaatttg gagaatgggg ttccaacata tgcatatgat
    19861 ttggaagagg ctgttaaaga cggatattta gtagcctatc attctatcga aaccaaactg
    19921 aaactaccta cggatggtct acattatgat gatttgtccg aagaagaaaa ggaacatttt
    19981 gatagcaaat ttgaagacga tagctgtgaa aaagatattg atgggagtgt gtttaattcc
    20041 tttattttca ataaaagtac agtagaaatt gttttaaatg aactcatgac aagaggaatt
    20101 cagacagcct cgggtgatga aattggtaaa actattattt ttgctaaaaa tcatgaccat
    20161 gcggaatata tcagaggtat ttttaacaac cgctatcctg aaaaagggag cgactatgct
    20221 caggtgattg attatagtat taagcattat cagaccttga ttgatgattt taaaattaag
    20281 gagaagtatc ctcaaattgc gatttctgtc gatatgttag atacaggtat tgatgtacca
    20341 gaggttgtta atttagtctt cttcaagaaa gtacgctcta aaactaagtt ttggcagatg
    20401 attggtcgag gaacccgtct atgtaaagat ttatttggac ctgagcagga taaggaaaac
    20461 ttcttggtat ttgattatgg ggataatttt gattattttc gtgcagatcc aagagatgga
    20521 gagggtcgtc acattgtttc gttgactcag cgtttattta atatcaaagt ggacttgatt
    20581 cgagaacttc agggactcca ataccaagaa gatcagtttg cgagagcata ccgtcagcag
    20641 cttgtctcgg aacttcaagg tcgtatagag agcttaaatg agttggactt cagggttcgt
    20701 atggttttag atacagttta tagctatagg aaattggaaa gttggcagaa tctaactgct
    20761 gttacaagtg aaaccattca aaaaaatctc tctccgcttt tatttgatga agataaagaa
    20821 gatgagatgg cgaggagatt tgatttgtgg ttgcttcata ttcagttggg gcaactgaca
    20881 gctaaatctt ccactgttca tatttcccaa gtgatgaaga cggctagagc tctttctgct
    20941 attggcaata tcccgcaggt ttttgagcag gctgaaatta tcaggaaagt acaggagcct
    21001 gaattttgga aagaagttaa cttgtctgat ttggaaaaaa ttcgtcttgc tattcgagat
    21061 ttattacagt ttttggataa aacagaccgt aaaccctact atgttaactt tgaagatcgt
    21121 atactctcca ctgttcacga gaccacagca tttttgcagg tcaacgatct tcggtcttac
    21181 aatgaaaaag ttgagcatta tttgaaaact catctggatg aggagtccat ttctaagcta
    21241 taccataata aaaagttgac atctgatgat atgcttgcac ttgaaaaatt gctctgggaa
    21301 aaattaggta gtaaagcaga ctaccaaagt cattatgaaa ataaggcaat tccgagattg
    21361 gttcgtgaga ttattggctt agatagagag tctgccaatc gtattttttc taaatttttg
    21421 tcggatgaga atcttaatgc caggcagatt tcatttgtaa aattgattgt agactacatt
    21481 gtagaaaatg gttttttaga gacgaaagtg ttaacgcaag agccgtttaa atcttatggt
    21541 tctgttcaac tactcttcca acaccaacta ccagtacttc gtaatattgt tcaaatcatt
    21601 gaacttatca ataatcgagc tggagaagcg gcttaaattc taaagtgatt gccatgctga
    21661 gactcattta aaattaaaaa gagtagaaat ttatgctata tatgagaagt tttattagga
    21721 agaatgtcat cgttttccta gaatacagta tcagttgtta agtggttgat aaatttcaaa
    21781 gtagatactt gtaccacgat gtttgttgat cgagttatta acaaaagagc tactttgatt
    21841 ttaaagaaat agaaaacaaa aagccgagca agaattcaat tgcaggagaa aatgaaataa
    21901 tactcaatga aaatcaaaga gcaaactagg aaactagctg caggctgctc aaaacactgt
    21961 tttgaggttg cagatggaag ctgacgcaga ttgaagagat tttcgaagag tataaatctt
    22021 cctaggataa agcaaaacgc atagtatcaa gggttttcaa cacttgatac tatgcgtttt
    22081 ctgatgttaa agactttcta ccaggttttt taaaagcata attgttagtt gtagtcattt
    22141 attattcttc aaagaaaaat ggtggggcga attttttcag ttcttcaaag cacttttgag
    22201 cagtatctgc atcttcacag atgataagac agacatcatt accacaaagg gtagcgatag
    22261 cgtcagggaa gctcaaagta tcaatgatag aaccaaagga ttgagccagt ccaggaaggg
    22321 tttttagtag gacttggtgt tgaactgggc gcatccagac aagggcgtct tccatgtaga
    22381 gttcgagacg tttttcccat tttgagatgg aaccattgtt aagaacataa taagcgctat
    22441 cttcttcgcg gacttttgat aggttcatat ttttgatgtc gcgtgagagg gttgcctggg
    22501 ttacttgaat gtcgttctca gcaagaaggg cttgcaactc agcctgtgta tgaatcttgt
    22561 tttttgtgat aagagcgcgt ataagttggt ggcggtgttc tgatttattc ataataatgt
    22621 aactcctttt agcaaggtaa ggtaagcatg gactgagcga ggtcgacagt caagtggtag
    22681 tctgtattgt cacggatggt gatttcaaag tcagtagtat agaggactaa acggagagtg
    22741 tctccttctt ttagcttgta aatagttggc tgcagttcaa attgaacgtc catccattca
    22801 tctgcagtaa tatcctctac taacagtaaa tcatttctat tttgtaaatt aaggtaacct
    22861 tttgtcacga ctcgttgtgc ctctggtcta aatggcaatt cacagagatt ttccaacatg
    22921 tgatagcgac cgttgtcaat ggttctagca cttaaaatag ctggataagg ttgtaggtat
    22981 ttcttttgcc caaattctag cagttgggca gataagagcc ccttgtttgt actggatttg
    23041 atacgaagat tgagctgagc gcgaccgttt aggtggagat ctttagtcac aggaaggtta
    23101 atagtaatct gattggcttt cccttgatag agctctgtat tgaaggtttg gtatgtctta
    23161 ccatagcgct caaaatcctt atctgggtac tggttttgaa tagcttgctc ttcttgacca
    23221 agtgagaagg tttcacagtt ttcttgccca ccgaagttat caagtgataa ccaagtctgt
    23281 ggagctgtat tgtcctgcca gataacagta ggaagttgaa agtctgtttc ctgtcctagt
    23341 aatttcttgg tcaataaggc atttatggac tcacggaagt caattgattg ccaattgttc
    23401 atgtaaacat gggcaccatt atggaaaaag agatgcttgt gtatatgagt aggaagagca
    23461 tggaacatct ggtaaacatg aagtggtttg acattccaat cctgagaacc atgagtaaag
    23521 acaacctctg cctttacttt atgggcattg agcagataat tgcggtcatg ccaaaactga
    23581 ttgtagtccc cagtttttcg gtctagctga gctttcactt tttctaagtc agcttggtga
    23641 gcttcattac cacggatata gtcgccagct aagagattac gagaataggt taactcagca
    23701 agggagtcaa agtcctcacc tggataacca cctgggctag tcaccagacc gttttcacgg
    23761 tagtagttgt accatgatga aattcctgcc tcggcaatga taacttctaa accatcgact
    23821 cctgtagtcg caagaccatt ggacatggta cctagatagg aaagtcctgt tgtagcaact
    23881 tttccgtttg accaatcagc cttgacttga cgctggcgcg tgtgatcagt aaaggcacgg
    23941 caacggccgt taagccaatc gatgacattt ttataagcct cgatttgctg gtagtctcca
    24001 ttagtcatga aacctgtcga gtctttggta ccaacacctg agacatagag attggcaaag
    24061 cctctcggaa ggaagtagtc gtttagtgta tagctagagt tgatgtgagt tagcttttcc
    24121 tcagcctctg ctataagctc agctttacct tggggttgga cgagatttag ttgaggtttc
    24181 tctagctcaa tcttgtgagg aagcttaacc tcaagctcgc cctccatctt gtagagagcc
    24241 ttgtcactag ccttgtcatt ggttccctga tgataagggc tggctgtcat gatggcaggg
    24301 atttttccat caaaacgagg gcgaataatg ctaaccttta ctaggtctga tagccctttt
    24361 tggtcagtat cgacacgaga ctcaacgtaa acgacttcac gaatgacatc ctggttagaa
    24421 aaagtagcca aactcttgcc gttaaagtag tggtagtcat tatcctccgg aataagacca
    24481 tcactaacaa gttggtcgat aagagtattt ccttttttgg tgcgagtatt gagtaactga
    24541 tagagatttt caatcaagtc accatatata atgggaaatc cagtttcttt acgaaaaacg
    24601 tcactatctt cgaagtcaac caaataagaa aagcctaaaa gttgaaaagc aacagtataa
    24661 aaaatatctg ctgtcagttc atcttctgat tgaaaaaatg tcagcaggtc tgttttttta
    24721 tcagctgcta ggatagaaag tgggtagttg gtgtcttgat aagtgaaaaa gaaacgacgt
    24781 aaaaaggttt caagtgagtc tttgtgattg gctgtatttt gtaaatcaaa gccacatttt
    24841 tttagttcag ataagacatt ttcttttgga aaattgatat aactatattg attaaaacgc
    24901 atagaacctc catatagaat gacagttaag gttattatat caaaaaaaaa gcagaaaggg
    24961 aattgttaac ttcaaaagga aataatccaa taaaaatgaa taaagtacta aattcaatat
    25021 agagaacaga gtaacaataa gaataaatag atagggtata
//
LOCUS       DAVLIK010000029        24394 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLIK010000029 DAVLIK010000000
VERSION     DAVLIK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24394
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.029"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..202
                     /locus_tag="VXE87_001312"
     CDS             <1..202
                     /locus_tag="VXE87_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0842849.1"
                     /translation="YIRLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSFL
                     KQLAKLYQVTTDYILEMDKFSC"
     gene            333..485
                     /locus_tag="VXE87_001313"
     CDS             333..485
                     /locus_tag="VXE87_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842850.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            652..2445
                     /locus_tag="VXE87_001314"
     CDS             652..2445
                     /locus_tag="VXE87_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0842851.1"
                     /translation="MKKNNVEIIKADSLVRRRGDNVERHLKRVAAYCRVSSDSEDQKN
                     SYDSQVRHYKEYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCANGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELVGFQGCLGYDYDVETKQISINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLEHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTAANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEEIAIEGAFLEAY
                     RQVYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRILLKKEENLVNLRLEGKVS
                     DSIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSNGEIDPAMLTIIFKTGEIQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDNTRGVCSVAGSILASQ"
     gene            2550..3137
                     /locus_tag="VXE87_001315"
     CDS             2550..3137
                     /locus_tag="VXE87_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV0842852.1"
                     /translation="MGGNPPIKNYTIVNKIVSSRKIERIVIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNVNSDYQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            3418..3666
                     /locus_tag="VXE87_001316"
                     /pseudo
     CDS             3418..3666
                     /locus_tag="VXE87_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            3771..4100
                     /locus_tag="VXE87_001317"
                     /pseudo
     CDS             3771..4100
                     /locus_tag="VXE87_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            4228..5457
                     /locus_tag="VXE87_001318"
     CDS             4228..5457
                     /locus_tag="VXE87_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0842853.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGLSVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            5477..8173
                     /gene="ppc"
                     /locus_tag="VXE87_001319"
     CDS             5477..8173
                     /gene="ppc"
                     /locus_tag="VXE87_001319"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0842854.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    8256..8473
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8586..9590
                     /locus_tag="VXE87_001320"
     CDS             8586..9590
                     /locus_tag="VXE87_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0842855.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            9659..10525
                     /locus_tag="VXE87_001321"
     CDS             9659..10525
                     /locus_tag="VXE87_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842856.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            10522..11280
                     /locus_tag="VXE87_001322"
     CDS             10522..11280
                     /locus_tag="VXE87_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842857.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            11370..13130
                     /gene="dnaG"
                     /locus_tag="VXE87_001323"
     CDS             11370..13130
                     /gene="dnaG"
                     /locus_tag="VXE87_001323"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0842858.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQDLYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            13133..14242
                     /gene="rpoD"
                     /locus_tag="VXE87_001324"
     CDS             13133..14242
                     /gene="rpoD"
                     /locus_tag="VXE87_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0842859.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            14256..14585
                     /locus_tag="VXE87_001325"
     CDS             14256..14585
                     /locus_tag="VXE87_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0842860.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            14700..15743
                     /gene="cpoA"
                     /locus_tag="VXE87_001326"
     CDS             14700..15743
                     /gene="cpoA"
                     /locus_tag="VXE87_001326"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0842861.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEENLLQIW
                     LDFYEKQAALGRK"
     gene            15759..17084
                     /locus_tag="VXE87_001327"
     CDS             15759..17084
                     /locus_tag="VXE87_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0842862.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            17115..17291
                     /locus_tag="VXE87_001328"
     CDS             17115..17291
                     /locus_tag="VXE87_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0842863.1"
                     /translation="MRSGRDKKIAGVCAGVAYYLDMDPTIVRVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            17350..17484
                     /locus_tag="VXE87_001329"
     CDS             17350..17484
                     /locus_tag="VXE87_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0842864.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            17548..18858
                     /gene="obgE"
                     /locus_tag="VXE87_001330"
     CDS             17548..18858
                     /gene="obgE"
                     /locus_tag="VXE87_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0842865.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVLVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLVTLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            18868..19026
                     /locus_tag="VXE87_001331"
     CDS             18868..19026
                     /locus_tag="VXE87_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842866.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            20075..21334
                     /locus_tag="VXE87_001332"
     CDS             20075..21334
                     /locus_tag="VXE87_001332"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0842867.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            21350..21901
                     /locus_tag="VXE87_001333"
     CDS             21350..21901
                     /locus_tag="VXE87_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0842868.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            21894..23171
                     /locus_tag="VXE87_001334"
     CDS             21894..23171
                     /locus_tag="VXE87_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0842869.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            23187..24047
                     /locus_tag="VXE87_001335"
     CDS             23187..24047
                     /locus_tag="VXE87_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0842870.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         7706 a         4024 c         5428 g         7236 t
ORIGIN      
        1 gtatatcaga ttaaagaatt taagagaaga caaagatttg tcccagtgtc aaattgcaca
       61 gtatcttcat tgttcacagt ctgcttattc tagaatagaa agtggcaagc aagatattcc
      121 tacatcattt ttgaaacaat tagctaaatt atatcaggta actacagatt atattttaga
      181 gatggataag tttagttgtt aataaatcct aagccctttg aaaactgaat aaaccgaggt
      241 gggactttct tatttgtcga gcactttagc ttgatacgcc gtgataggag cgataattat
      301 tagctataaa atagagtggt tctctatctg ccatgactac aaataaggat aatgatactt
      361 ctgaacgttc aggctgccag cgaaaaagga cagcgggtga aatgcccatg aatgatttaa
      421 ccagtcatac ccacggagga aattatacat gttacaagga ggaaaaagtt tggaacaatc
      481 agtaataaag tatactatgc aactatcaat gcttaacttt ttatactcaa gaaatatgtt
      541 atctaaaaat gagtatgaca agattagaaa caaactgcgt attaagtaca caaaatagct
      601 gactttttga tttgaatgcg gtaatataga atcaaaagga ggaatttcag tatgaaaaaa
      661 aataatgttg aaataataaa agctgattct ttagttcgtc gaagaggcga caatgtagaa
      721 agacacttaa agagggttgc tgcttattgc agagttagtt ccgatagtga ggatcagaaa
      781 aacagttatg attctcaagt aagacactac aaagaatata tttctcagcg ttcagattgg
      841 gagctggcag atatttatgc agatgaaggt atttcaggaa cacaagtagg aaagagacaa
      901 gattttcaac gattaatcaa tgattgtgca aatggagaga tagattatat tgtcacaaaa
      961 gcaattgcta gatttgcaag gaatacccta gatactttga agtatgtcag aatgttaaag
     1021 gatatgcaaa ttggagtata ttttgaggaa gaaaacatag ataccctaac aatggatgga
     1081 gaattgcttc taactattct aagctccgtt gcacagcaag aagtagagaa tacttctgcc
     1141 catgtgaaaa aaggattaaa aatgaagatg caacgtggtg aattggttgg ttttcaaggg
     1201 tgcttagggt atgattatga tgtagaaacc aagcagattt caattaataa aaaagaagcc
     1261 aaaattgttc gttatatttt tgaaaggtat ctagaaggta ttggaggaaa agtaattgca
     1321 agggaacttg atgaacttgg ttacaaatcg ccaagaggtt tagaacactg gaatgataca
     1381 acagttctag gaataataaa gaatgaaaaa tataaaggtg atattctaat gggaaaaact
     1441 tttacagttg acccaataag caagagacgg ttgagtaatt ttggagaaga agataagtac
     1501 tatatcaagg ataatcatga accaataata tctaaagaag attttgaaaa agctcaggag
     1561 attagattgc gtcgagcagg aaataagaag acagctgcga atgtaaatgg gaagcgtgaa
     1621 cgctattcaa aaatgtatgc ttttagtagc atgttggaat gtggtttttg tggttcaata
     1681 ttatctagaa gaagttggca ctgccgttca gattatcgca aagttgtgtg gcactgtgtt
     1741 acatcgataa agaaaggaaa gaaattttgt aagcatagta aaggattaga agagatcgcc
     1801 attgaggggg ctttcctgga agcttacaga caagtctatc attcaaatga aaatttaatg
     1861 acagacttac ttgaaacgat agaatctgaa ttgaatgaca atagccttaa caaggaacta
     1921 aaaaggatta caaacaaact tcgaatatta ctaaaaaaag aggagaatct tgtaaatcta
     1981 aggctcgaag gaaaagttag cgattccata tacaatgaaa agtacaatga aatttcctca
     2041 gaaaaagagt ttctagcaga agagaaggta aatattgaaa caacattaaa atcagaaatc
     2101 gatgtaaaga aaagactaac tgagtttaag cacttgctat cttcgcaaaa aatgcttacg
     2161 gagtttgatc gtgcagtttt tgaaagtatt gttgagaaaa ttattgtagg tggagttaat
     2221 agcaacggag aaattgatcc tgcaatgtta accataatat tcaaaacagg tgaaattcaa
     2281 aacaaggatg gtaaacaatt taaaagtaaa cgtaaaaatg ctaaactaga aacagataaa
     2341 ttgtgtcctc aaaacagtga cgaggataaa aaattgtatt ctcaaggaac agacaacaca
     2401 cgtggagtgt gtagtgttgc tggttcgatc ttagccagtc aataaaatga tatgttttaa
     2461 aaaaattata atttcgaaac gtgaataaac ttgtttaaac tttatgtatc tttagaaagt
     2521 gtgataactt gaaagaacaa atttttttga tgggtgggaa tccgccgata aagaactata
     2581 cgattgttaa taaaattgtg tcatcaagga agatcgaaag aattgtcatt tttacagttt
     2641 ttcgagaaaa ttgggaaccg tacatgaaaa agtacacgga agtttttcaa agtcaatttc
     2701 ctaatctaaa cattgattac ttgctcctgg acactgagca gattgatctt gatagctatc
     2761 tagatgctga cataattatc atcggtggtg gaaatacgga aaaatatatt gctacttatg
     2821 ttaatcagga gttcaaaagt tatatcgatc atatgcttaa taaagaggca aaaattatag
     2881 gattttctgc aggagcccta ctattaggag aaaaagtcta tgtctcacct aatgttaatt
     2941 cagattatca gataaagata aaaaatggat taggactttt tagtcagttt ttaattagtg
     3001 tccattatga ttcctggaat gataaagcaa ataaggatag agctgaagaa ctcgttaatg
     3061 ttcccataat tccactaaat gatcattctt gtcttgtatt ggataaactt ggaaacatca
     3121 tagagaaaat tgactaactt tcataatgta aaaatggatc taggaaataa aagtgtagac
     3181 gaactggata ggttactagt gaaaactgca aaaagtgttg taaagtgaat cggagtgtgc
     3241 ttgatggatt ttagtagtaa gatagccata aataaaggct ggtcagatga taaaaaatat
     3301 tgtgtgacag ttcaaaatca gtaaacatat ttcttgcgtg tttctgataa gtcgaagtta
     3361 gattataaaa aaattgaatt tgatacgatg gagaaagtag cttctcttgg agttccgatg
     3421 tgtaaaccaa ttagcattga actctgcgat gacgaagtac attctttaca cgaatggata
     3481 gacggaagag atgcaataga tagcatttta acttattcat aaaaccaaca atacacatat
     3541 ggtgtagaag caggaaagat acttagaaag attcatacaa ttcctgctac agaagtttgt
     3601 gaagattggg aaatcttttt taatctaaaa attgatgata aaatctccaa cgaaatgata
     3661 tggtaagtcc gaaacgctca gtgtgtaagc ttgttgctaa aagcgtaaaa accttggaac
     3721 gaaaggaata atagacttcc tgcgaaacaa aaatacaata caataaaact atggatgatg
     3781 aagcaagtaa acaattgagc gatagccgtt tcaagatcct tgtaggtgtt cagcgcacga
     3841 cttttgaaga gatgttagct gtgttaaaaa cagcttatca acgtaaacgc gcaaaaggtg
     3901 gacgaaaaac caaattaagc ctagacgatc tccttatggt aactattcaa tacatgcgag
     3961 aatagcgcac ttatgaacaa atttcggctg attttggcat tcacgaaagc aacttaatcc
     4021 gtcggagtca atgggttgaa gtaactcttg ttcaaaatgg ttttacgatt tcaaattctg
     4081 ctctaattat gaaaaacagt aaaattcgaa ggattataag gtaagagttt ttttctttct
     4141 gaaaaaatgg tataatagca atcaaaacta gaaaataaaa cggaatttgg aacagatttg
     4201 tctgtatcct agtagagtgg tgatgctatg aagattagta agaggcactt attaaattat
     4261 tccatcttga ttccctactt gcttttatct attttgggct tgattgtggt ctattcgacc
     4321 accagtgcta ttttaattga agaaggcaag agtgccttgc agttggttcg aaaccaagga
     4381 atcttttgga ttgttagttt gatactgatt gccttaattt ataaattgag actagatttt
     4441 ttgagaaatg agcgactaat cattttagtt atattaatag aaatgcttct attgttcttg
     4501 gctcgtttta ttggtctttc cgtaaacggg gcatacggtt ggatttcggt tgcaggagta
     4561 actattcagc cagctgagta cttaaaaatc attattattt ggtatttagc tcaccgattc
     4621 tccaaacagc aagaagaaat agctacttat gattttcaag ttttgactca aaatcaatgg
     4681 cttccccgtg cttttaatga ttggcgattc gttctcctag ttctgattgg aagtttggga
     4741 attttccctg atttaggaaa tgcgactatt ttagtcttgg tttccttgat tatgtataca
     4801 gttagtggaa tcgcttatcg ctggttttca accattctgg cgctcgtatc tgccgcttct
     4861 gtctttgtct tgaccactat cagcctaatc ggtgttgaga ccttttcaaa aattccagta
     4921 ttcggctatg tagccaagcg ctttagtgcc ttttttaatc cttttgccga tcgtgctgat
     4981 gcaggtcacc agttagctaa ttcttatttt gccatggtca atggcggttg gtttggtcta
     5041 ggtcttggaa actcgattga aaaacgaggt tatttgccag aagctcatac agactttgtc
     5101 ttttctatcg tgattgaaga atttggcttt gttggtgcca gtcttatttt agctctcttg
     5161 tttttcatga ttttgcggat tatcttggtc ggtatccgag cggagaatcc tttcaatgcc
     5221 atggttgcac tcggtgtcgg agggatgatg ttggttcagg tatttgtcaa tatcggaggg
     5281 atttcgggct tgattccatc tacaggagtg actttcccct tcttatccca gggtggaaat
     5341 agtcttctag tcttatcagt ggcagtagcc tttgtcttaa atattgatgc cagtgaaaaa
     5401 cgcgctaaat tgtaccgaga attggaaaat caaccaatga accttctgtt gaagtaggat
     5461 aaagaaagga tagtttatgt ctcttcaaaa attagaaaat tatagtaata aaagtgttgt
     5521 gcaagaagaa gtcttgattc taacagaatt actggaagat attactaaaa atatgcttgc
     5581 cccagagacc tttgaaaaaa taatacagtt gaaagaatta tcaacgcagg aagattatca
     5641 aggtctaaac cgtctagtga ctagcttatc aaatgatgaa atggtctata tttcacgcta
     5701 tttctctatc ttgcctcttt tgattaatat ttcagaggat gtggatttag cttatgaaat
     5761 caatcatcaa aataatattg atcaggacta tttaggtaaa ttatctacaa cgattaaatt
     5821 ggtagcagaa aaggaaaatg ccgttgagat cctagaacac ttgaatgttg tccctgtttt
     5881 gacagcccat ccaacacaag tgcaacgcaa aagtatgttg gatttaacaa atcatattca
     5941 tagtcttttg cgtaaatacc gtgatgttaa gttggggttg atcaataaag ataaatggta
     6001 caatgatttg cgtcgttaca tcgaaattat catgcagaca gacatgattc gtgagaaaaa
     6061 attaaaagtg actaacgaaa tcacgaatgc tatggaatat tataacagct cctttttgaa
     6121 agctgtacct catttgacga cggagtataa gcgcttagcg caagcgcatg gtctgaattt
     6181 aaaacaggct aaaccaatca ccatgggtat gtggataggt ggtgaccgtg atggaaatcc
     6241 atttgttaca gcaaagacct tgaagcagtc tgcactcact cagtgtgaag tcatcatgaa
     6301 ctactatgat aaaaagattt accaacttta tcgtgaattt tctctttcaa ctagcattgt
     6361 caacgtcagc aagcaagtca gagaaatggc tcgtcaatcc aaggataact cgatttaccg
     6421 cgaaaaagag ctttaccgtc gtgccttgtt tgatattcaa tcaaaaattc aggcaactaa
     6481 aacctatctg attgaggatg aagaagttgg gactcgttat gaaaccgcca atgatttcta
     6541 caaggatttg attgccattc gagattctct actagaaaat aagggcgagt ccttgatttc
     6601 aggtgatttt gtggaattat tgcaggcagt agagatattt ggtttttact tagcatcaat
     6661 tgatatgcga caagactcta gcgtctatga agcctgtgtg gcagaactct tgaaatcagc
     6721 aggaattcat tctcgttata gcgagttgag cgaagaagaa aagtgtgacc ttctcttgaa
     6781 agaattagaa gaagatcccc gaattctttc tgcgactcac gcagaaaaat cagaattatt
     6841 agcaaaagaa ttagctattt ttaagacggc tcgtgttttg aaagataagt tgggagatga
     6901 tgtcatccgt cagaccatca tttcacatgc aaccagcctt tctgatatgc tagaattagc
     6961 tattctgtta aaagaagtag gactggtgga tacggaaagg gcgcgtgttc agattgttcc
     7021 cctttttgaa acaattgaag acttggatca ttcagaggaa acaatgagaa aatatctttc
     7081 tcttagcctt gccaaaaaat ggattgactc acgaaataac taccaagaaa tcatgcttgg
     7141 ctactctgac agtaataaag atggcggtta cttgtcatca tgttggaccc tctacaaggc
     7201 tcaacaacaa ttgactgcta ttggagatga atttggcgtt aaggttacct tcttccatgg
     7261 tcgtggtggt actgtcggtc gtggtggtgg gccaacctat gaagccatta catctcaacc
     7321 gctcaagtct atcaaggatc gtatccgctt gacggagcag ggtgaagtaa ttgggaataa
     7381 atacggtaac aaagacgccg cttactataa ccttgaaatg ctagtatcgg cagctattaa
     7441 ccgtatgatt actcagaaga agagcgatac caatacccca aatcgttatg aagccattat
     7501 ggatcaagta gtggaccgta gttacgatat ctaccgtgat ttggtctttg gtaatgagca
     7561 tttctatgat tatttcttcg agtcaagtcc aatcaaggct atttcaagtt ttaatattgg
     7621 ttctcgtcca gccgctcgta agactattac tgaaatcggt ggtttgcgtg ccatcccttg
     7681 ggtattctca tggtcacaga gtcgtgttat gttccctgga tggtacgggg ttggttcaag
     7741 cttcaaggaa tttatcaata aaaatccaga gaatattgct atcttacgag atatgtacca
     7801 aaattggcct ttcttccaat cgcttctttc aaatgttgat atggttttgt caaaatcaaa
     7861 tatgaatatt gcttttgaat atgctaaact ttgtgaagac gagcaagtta aggccatcta
     7921 tgagactatt ttaaatgaat ggcaagttac taagaacgtt atcttggcta ttgaaggaca
     7981 tgacgaactc ttagctgaca atccatatct aaaagctagt ctggattacc gtatgcctta
     8041 ctttaatatt ctcaactata ttcagttaga gttgattaaa cgccaacgtc gtggagaatt
     8101 gtccagtgat caagaacgat tgattcatat caccatcaac ggaattgcga caggattgcg
     8161 taattcaggt tgataatttt caagagtgaa tgctaaaagt gaatatcaaa aaaattctaa
     8221 tagactattg acaagtagtt taaaaatgat ataatttaac cattcagaaa agtaatcata
     8281 caaacttttt agagagtctg tggtagctga aaacagataa gtggcaatga tgaaaattgg
     8341 gctgaatgct atttagaatt tgaaattata aaaattcggt aagcacacct tacagtgcat
     8401 ctcgttattg cgagactgag cgatagggaa attccctata attgaggtgg taccgcgcat
     8461 cgacgtcctc acacaagttt tttgtgtgag gatttttttg atggaggtta gtatggaaag
     8521 aaaacgatgg cgtcgcttgt ttagataagt gaaatatgtt aaaggaaata aaaaggagaa
     8581 acagaatgaa aaataaacgt ttaattggaa ttattgctgc attagcagtc ttagtagcag
     8641 gaagcttgat ttattcttca atgaataaat cagaagttca gaataataag gatgagaaga
     8701 aaataaccaa gattggtgtg cttcaatttg tgagccatcc atcccttgat ttgatttata
     8761 aagggatcca agatggactt gcagaagaag gatataaaga tgatcaagtt aaaattgatt
     8821 ttatgaactc agaaggtgac caaagtaagg ttgcgacaat gagtaaacaa ttggttgcaa
     8881 atgggaatga ccttgtggtt ggtatcgcaa caccagcagc ccaagggttg gctagtgcaa
     8941 caaaagacct accggttatc atggccgcta ttacagaccc aattggtgct aacttggtta
     9001 aagatttgaa aaaaccaggt ggcaacgtta caggggtatc tgaccacaat ccagctcaac
     9061 aacaagttga actcatcaag gctctgacac cgaatgtgaa aacaatcgga gctctttact
     9121 caagtagcga agacaattca aaaacacagg tcgaagaatt taaggcttat gctgaaaaag
     9181 caggtctgac agtggaaaca tttgcagttc cttcaacaaa tgaaattgcc tcaactgtca
     9241 ctgttatgac tagcaaggta gatgctattt gggttccaat tgataacacc attgcatcag
     9301 gatttccaac ggttgtctct agcaatcaaa gttctaagaa accaatttat cccagtgcga
     9361 cagctatggt agaagtaggt ggtttggcat cagttgtaat tgaccaacat gaccttggtg
     9421 tggcaacagg taaaatgatt gtgcaagtct tgaaaggtgc aaaaccagcc gataccccag
     9481 tcaatgtctt ttcaactggt aagtcagtca tcaataaaaa aatagcacaa gaactaggta
     9541 ttactattcc tgagtctgtt ctcaaagaag caggacaagt catcgaataa ataaggtagg
     9601 gaggaggaga ctcttcccat tttttaaaaa gatgaatata gaaaggatta aataaaatat
     9661 gattgtttcc attatttctc aaggatttgt ctgggctatt ctaggtctgg gaatctttat
     9721 gacatttagg attttaaact ttccagatat gacgacagaa ggttccttcc ctcttggggg
     9781 agctgttgct gtcactttga taaccaaagg cgtgaaccca tttttagcga cacttgttgc
     9841 tgtaggagca ggttgtttgg ctggaatggc agcaggcctt ctttatacaa aagggaagat
     9901 cccaaccttg ctctcaggga ttttggtgat gacttcttgt cactcaatca tgctcttgat
     9961 tatgggacgt gcgaatttag gcctgcttgg aaccaagcaa attcaggatg ttttgccttt
    10021 tgattcggat ttgaatcaac tcttgacagg tctcatcttt gtgagtattg ttattgctct
    10081 catgctcttt ttcttggaca ctaaactcgg acaagcctat attgctacag gggataatcc
    10141 tgatatggct agaagtttcg ggattcatac tggacgcatg gagctcatgg gcttggtctt
    10201 atcaaatggt gtgattgccc ttgcaggtgc cctcattgct cagcaagaag gttatgccga
    10261 tgtgtctcga gggatcgggg ttatcgttgt ggggcttgca agtttgatta ttggagaagt
    10321 tattttcaag agtttgagct tggcagagcg tttggttact atcgttgtag gttctatcgc
    10381 ttatcaattt ttagtgtggg cagttatcgc acttggcttt aatacaagtt accttcgttt
    10441 atacagtgcc ttgattttag cagtctgcct catgattcca acatttaagc aaacaatctt
    10501 gaaaggagcc aagttaagca aatgacagca attgtagaat taaaaaatgc aaccaaaatc
    10561 gttaaaaatg gctttgatga agaaaagatt attttaaatg atgtttcctt agaaattttt
    10621 gaacaggact ttatcacgat tttgggtgga aatggtgctg gtaaatcaac cctctttaac
    10681 actattgcag gaaccatatc actaaccagt ggaactatcc gtattttagg tgaggatgtt
    10741 accaagtttt caccagagaa gcgcgctaag tatctgtctc gagtcttcca agatccaaag
    10801 atggggacag ctcctcgtat gacagtggca gagaatctcc tgattgccaa gtttcgtggt
    10861 gaaaagcgtg gactatttcc gagacgtctg gctagctata aggataagtt tcaggcgacc
    10921 attgaaaaag tgggaaacgg tcttgagaaa cacttgaata caccgattga gttcttatct
    10981 ggtggacaaa gacaggcttt gagtctcttg atggcaacct tgaagcgacc tgaattactc
    11041 ttgttagacg agcatactgc tgccctggat ccaaagacta gtgttgcttt gatggaattg
    11101 acagatgaat ttgttaagaa agatcaattg acagccctta tgattaccca tcatatggaa
    11161 gatgctctca aatatggcaa tcgcttgatt gtcatgaaag aaggacggat tatccaagat
    11221 ttaaaccaag aagaaaaagc aaaaatgaaa atctctgatt attatcaact ctttgaataa
    11281 agtaaggaaa atgagtgaaa tggtttactt tttttctgaa ataaagtata ctatataaag
    11341 taaactatga taacatggag gtattgtgta tggttgacaa acaagtcatt gaagaaatca
    11401 aaaacaatgc caacattgtg gaagtcatag gagatgtgat ttctttacaa aaggcaggac
    11461 ggaactatct agggctctgt ccttttcatg gtgaaaaaac accttctttc aacgttgtag
    11521 aggataagca gttttatcac tgtttcggtt gtggtcgctc aggtgatgtc tttaagttca
    11581 tagaggagta ccaaggggtt ccctttatag aggcagtcca aatcttaggt cagcgtgttg
    11641 gaattgaggt tgaaaaaccg ctttatagtg agcaaaagtc agcctcacct caccaagatc
    11701 tttatgatat gcacgaagat gcagccaaat tttaccatgc tattctcatg acaacgacta
    11761 tgggcgaaga ggccagaaat tacctttatc agcggggttt gacagatgaa gtgcttaaac
    11821 atttttggat tggtttagca cctccagaac gaaactatct ctatcaacgt ttgtctgatc
    11881 agtatcgtga agaggattta ctggattcag gcctgtttta tctctcggat gccaatcaat
    11941 ttgtagacac ctttcacaat cgcattatgt ttcccctgac aaatgaccaa ggaaaggtca
    12001 ttgccttctc aggtcgtatc tggcaaaaaa cggattcaca aacttctaag tataaaaaca
    12061 gccgatcgac tgcaattttt aacaaaagtt acgaattata tcatatggat agggcaaaaa
    12121 gatcttctgg aaaagctagt gagatttacc tgatggaagg attcatggat gttattgcag
    12181 cctatcgggc tggaatcgaa aatgctgtgg cgtcgatggg aacggccttg agtcgagagc
    12241 atgttgagca tctgaaaagg ttaaccaaga aattggttct tgtttacgat ggagataagg
    12301 ctgggcaagc cgcgacattg aaagcattgg atgaaattgg tgatatgcct gtgcaaatcg
    12361 ttagcatgcc tgataacttg gatcctgatg agtatctaca aaaaaatggt ccagaagact
    12421 tggcctatct attaacaaaa actcgtatta gtccgattga gttctacatt catcagtaca
    12481 aacctgaaaa cagtgaaaat ctgcaggctc agattgagtt tattgaaaaa atagctccct
    12541 tgattgttca agaaaagtcc atcgctgctc aaaacagcta tattcatatt ttagctgaca
    12601 gtctggcgtc ctttgattat acccagattg agcagattgt taatgagagt cgtcaggtgc
    12661 aaaggcagaa tcgcatggaa agaatttcca gaccgacgcc aatcaccatg cctgtcacca
    12721 agcagttatc ggctattatg agggcagaag cccatctact ctatcggatg atggaatccc
    12781 ctcttgtttt gaacgattac cgtttgcgag aagactttgc atttgctaca cctgaatttc
    12841 aggtcttata tgacttgctt ggccagtatg gaaatcttcc tccagaagtt ttagcagagc
    12901 agacagagga agttgaaaga gcttggtacc aagttttagc tcaggatttg cctgctgaga
    12961 tatcgccgca ggaacttagt gaagtagaga tgactcgaaa caaggctctc ttgaatcagg
    13021 acaatatgag aatcaaaaag aaggtgcagg aagctagcca tgtaggagat acagatacag
    13081 ccctagaaga attggaacgt ttaatttccc aaaagagaag aatggagtaa taatggcaac
    13141 aaaacaaaaa gaagtaacaa catttgacgt acaggtagca gaatttatcc gtaatcataa
    13201 gcaaaaaggg acagcaacag atgatgaaat caatgcaagt ctggttattc cttttacctt
    13261 ggacgctgat gggattgaag atctcttgca acggattcag gatgcaggca tttctatcac
    13321 agataacgaa ggaaatccaa gtgcgcgtgt tctcagcaat gaagaagaac cagaactcag
    13381 cgatgaggac ttgattgggt caacttctgc taaggtcaat gaccctgtcc gtatgtactt
    13441 gaaagaaata ggggtcgttc ctctcttgac caatgaagag gagaaagagt tggcactggc
    13501 tgttgaagct ggtgatatcg aagccaaaca acgtcttgcg gaagccaatc ttcgtttggt
    13561 tgtttccatt gccaaacgct atgtcggtcg tggtatgcag ttccttgact tgattcaaga
    13621 aggaaatatg ggcttgatga aggcggttga caagtttgac tattctaaag ggttcaagtt
    13681 ttcaacttat gcaacttggt ggattcgtca ggctatcact cgtgctattg cggaccaagc
    13741 tcgtaccatc cgtatcccag ttcacatggt tgaaactatc aataaattgg ttcgtgaaca
    13801 gcggaatctc cttcaagaat tggggcaaga tccgacacca gaacagattg ctgaacgaat
    13861 ggatatgaca cctgataagg ttcgtgaaat cttgaagatt gcccaagaac cagtatctct
    13921 tgaaactcct atcggtgaag aggacgatag ccaccttgga gactttatcg aagatgaagt
    13981 gattgaaaat ccagtggatt atacgactcg tatcgtcttg cgtgagcaat tggatgaaat
    14041 cttagatact cttacagacc gtgaagaaaa tgttctgcgt ctacgttttg gactagatga
    14101 tggaaaaatg cgcacacttg aagatgtggg gaaagtcttt aacgtaactc gtgagcgtat
    14161 ccgtcagatt gaagcaaagg ctttgagaaa actacgccaa ccaagtcgta gcaaaccgct
    14221 tcgtgatttt attgaagact aagagtgagg aaaatatggc ttatacagaa gagcaaattg
    14281 aaaacatcaa aacacggatt ttaacagcct tggaagaagt catcgaccct gagttgggaa
    14341 tcgatattgt caatcttggt ttgatctatg agattcgttt tgacggtgac acagggcaaa
    14401 cagagattga catgactttg acaactatgg gttgtccctt agcagacctt ttgacagacc
    14461 agatttatga tgctatgata gaggttccag aagtaacgga tactgaggtt aaattagtct
    14521 ggtatccagc ctggacagtt gaaaaaatga gtcgctatgc ccgcattgcc ctaggcatta
    14581 agtaaacata taaaagcatg tgagagactg ttggaaaagc gaggaaattt cccctctttt
    14641 cctctagtct ctcctttctt ttgctgattt tattcaaaga aaatgatata atagtagtta
    14701 tggagaaaaa gaaattacgc atcaatatgt tgagttcaag tgagaaagta gcaggacagg
    14761 gagtttcagg tgcttaccgt gaattagttc gtcttcttca ccgtgctgcc aaggaccaat
    14821 tgattgttac agaaaatctt ccaatcgagg cagatgtgac tcactttcat acgattgatt
    14881 ttccctatta tttatcaacc ttccaaaaga aacgctcagg gagaaagatt ggctatgtgc
    14941 atttcttgcc agctacactt gagggaagtt tgaaaattcc atttttctta aagggaattg
    15001 tgaaacgcta tgtattttct ttttacaacc ggatggagca cttggttgtg gtcaatccta
    15061 tgtttattga ggatttggta gcagctggta ttccacgtga aaaagtgacc tatattccta
    15121 actttgtcaa caaggaaaaa tggcatcctc taccacaaga agaggtagtc agactgcgca
    15181 cagatcttgg tcttagtgac aatcagttta tcgtagtagg tgctgggcaa gttcagaaac
    15241 gtaaagggat tgatgacttt atccgtctgg ctgaggaatt gcctcagatt acctttatct
    15301 gggctggtgg cttctctttt ggtggtatga cagatggtta tgaacactat aagaaaatta
    15361 tggaaaatcc ccctaaaaat ttgatttttc caggcattgt atcgccagag cggatgcgcg
    15421 aattgtatgc tctagcggat cttttcttgt tgcctagtta caatgagctc tttcctatga
    15481 ctattttaga agctgcgagt tgtgaggctc ctattatgtt gcgtgattta gatctctata
    15541 aggtgatttt ggagggaaat tatcgggcga cagcgggtag agaagagatg aaagaggcta
    15601 ttttggaata tcaagcaaat cctgctgcct taaaagatct caaagaaaag gctaagaata
    15661 tttccagaga gtattctgaa gagaatctgt tacaaatctg gttggacttt tatgagaaac
    15721 aagccgcttt agggagaaag taaaaagtga ggtaatctat gcgaattggt ttatttacag
    15781 atacctattt tcctcaggtt tctggtgttg cgaccagtat tcgaaccttg aaaacagaac
    15841 ttgaaaagca gggacatgct gtttttatct ttacgacgac agataaggat gtcaatcgct
    15901 acgaagattg gcaaattatc cgcattccaa gtgttccttt ctttgctttt aaggatcgtc
    15961 gctttgccta ccgaggtttt agcaaggcac ttgaaattgc taaacagtat cagctagata
    16021 ttatccatac tcagacagaa ttttctcttg gcctgttggg gatttggatt gcgcgtgaat
    16081 tgaaaattcc agtcatccat acctatcaca cccagtatga agactatgtc cattatattg
    16141 ctaaggggat gttgatccgg ccgagtatgg tcaagtatct ggttagaggt ttcctgcatg
    16201 atgtggatgg ggttatttgt cctagtgaga ttgtccgtga cttgctatct gattataagg
    16261 tcaaggttga aaaacgggtc attcctactg ggattgaatt agccaagttt gagcgtccgg
    16321 aaatcaagca ggaaaatttg aaagaactgc gtagtaaact agggattcaa gatggtgaaa
    16381 agacgttgct tagtctttcg agaatctctt atgaaaaaaa tattcaagca gttttagcag
    16441 cctttgctga tgttctgaaa gaggaagaca aggttaaact ggtagtagct ggggatggcc
    16501 cttatctgaa tgacctcaaa gagcaagctc agaacctaga gattcaagac tcagtcatct
    16561 ttacagggat gattgctcct agtgagacgg ctctttacta taaagcggcg gatttcttca
    16621 tttcggcatc gacaagcgaa acgcaaggtt tgacctactt ggaaagctta gccagtggaa
    16681 cacctgtcat tgctcacgga aatccttatt tgaacaacct catcagtgat aaaatgtttg
    16741 gaaccttgta ctatggagaa catgatttgg ctggtgctat tttggaagcc ctgattgcaa
    16801 caccagacat gaacgagcat accttatcag agaaattgta tgagatttca gctgagaact
    16861 ttgggaaacg agtgcatgag ttttatctgg atgctattat ttcaaataac ttccagaaag
    16921 atttggctaa agatgatacg gtcagtcagc gtatctttaa gacagttttg tatcttccgc
    16981 aacaggtggt tgctgtacct gtaaaaggtt ctagacgcat gttgaaggct tcaaaaacac
    17041 agttgatcag tatgagagac tattggaaag accatgaaga atagaaagag gaacagctat
    17101 gaaaaaaaca attaatgaga agcggtcgtg ataaaaagat tgcgggtgtt tgtgctgggg
    17161 tggcctatta tctggatatg gatccgacta tcgttcgagt catttggggt gttcttactt
    17221 gctgttacgg agctggaatt gtagcttaca ttattttatg gattatcgca ccagtagcaa
    17281 ctgactattg aaaactagct caattcatgc taagataata gaaaatagaa tgtaacgaag
    17341 gagagaaaaa tggcatttgg agataatgga aatcgtaaaa aaactatgtt tgagaaaata
    17401 accttgttta tcgtgattat catgctagta gcaagtttat tgggaatttt tgcaactgca
    17461 attggtgccc tcagtaatct ataaaataga ttcaagaaaa tttagtgact gggatttccc
    17521 agcccttttt taaagtgaga agaaataatg agtatgtttt tagatacagc taagattaag
    17581 gtcaaggctg gtaatggtgg cgatggtatg gttgcctttc gtcgtgaaaa atatgtccct
    17641 aatggaggcc cttggggtgg tgatggtggt cgtggaggca atgtggtctt cgttgtagac
    17701 gaaggactac gtaccttgat ggatttccgc tacaatcgtc atttcaaggc tgattctggt
    17761 gaaaaaggga tgaccaaagg gatgcatggt cgtggtgctg aggaccttag agttctagta
    17821 ccacaaggta cgactgttcg tgatgcggag actggcaagg ttttaacaga tttgattgaa
    17881 catgggcaag aatttatcgt tgcccacggt ggtcgtggtg gacgtggaaa tattcgtttc
    17941 gcgacaccaa aaaatcctgc accggaaatc tctgaaaatg gagaaccagg tcaggaacgt
    18001 gagttacaat tggaactaaa aatcttggca gatgtcggtt tagtaggatt cccatctgta
    18061 gggaagtcaa cacttttaag tgttattacc tcagctaagc ctaaaattgg tgcctaccac
    18121 tttaccacta ttgtaccaaa tttaggtatg gttcgcaccc aatcaggtga atcctttgca
    18181 gtagccgact tgccaggttt gattgaaggg gctagtcaag gtgttggttt gggaactcag
    18241 ttcctccgtc atatcgagcg tacacgtgtt atccttcaca tcattgatat gtcagctagc
    18301 gaaggccgtg atccatatga ggattaccta gctatcaata aagagctgga gtcttacaat
    18361 cttcgcctca tggagcgtcc acagattatt gtagctaata agatggatat gcctgagagt
    18421 caggaaaatc ttgaagaatt taagaaaaaa ttggctgaaa attatgatga atttgaagag
    18481 ttaccagcta tcttcccaat ttctggattg accaagcaag gtctggtaac acttttagat
    18541 gctacagctg aattgttaga caagacacca gaatttttgc tctacgacga gtccgatatg
    18601 gaagaagaag cttactatgg atttgacgaa gaagaaaaag cctttgaaat tagtcgtgat
    18661 gacgatgcga catgggtact ttctggtgaa aaactcatga aactctttaa tatgaccaac
    18721 tttgatcgtg atgaatctgt catgaaattt gcccgtcagc ttcgtggtat gggggttgat
    18781 gaagcccttc gtgcgcgtgg agctaaagat ggggatttgg tccgcattgg taaatttgag
    18841 tttgaatttg tagactagga gactggtatg ggagataaac cgatatcttt ccgagatgcg
    18901 gatggtaatt ttgtttccgc cgcagacgtt tggaatgaaa agaaattgga agaactattt
    18961 aatcgtctca atccaaatcg tgccttgaga ttggcacgaa ctaaaaagga aaatccatct
    19021 cagtaaagaa gctaaaaaat cccgtgcctc atcagacacg ggattttgtg gtacgacagg
    19081 catgtatagc aaactgaatc tggaatagca cagcatatct tctaaaatat tgttataaat
    19141 tgatttgaat ttcaaaatta aattgtttga ttcttatttc aatttgttat agtatatctg
    19201 atgtcaaagt tctcggcgag tcaaatagcg attcccaagc ctgactatcg tgaggtagtg
    19261 gattaaaacg gtctggggat agaccgtttt aagtctgacg ctggaaataa gaatcgtcag
    19321 aggaagggat agcgaaatcg tggctttacg aacaggaacg tgatagtaag gcgtatatag
    19381 cggataaggg ggtctcaaac tctaaagtcc aaaaaggtag tcgtaaccta tatgcgtaaa
    19441 tcacgagagt aattgaattc gtactaagat tttctatttt cactgtaacc ttttaacgtc
    19501 cttatatctt gtatacacga ggaaagatgt acgacttatc ccgtgaggtc tatcactata
    19561 aagagaaaac gacagataga agtgatcctg agtcacggtt atctttaaaa tagattgtct
    19621 gataggacgg tatgtataaa acgcttctgt gaactgagag aaggggagaa gttcttgcta
    19681 aaatttagtt gaacagccgt attccgatac ttagataaga gatctagtct tagatcctac
    19741 tcagttttag gggataaaaa aggggcaata gcgattcgag aaagattata ctcttcgaaa
    19801 atctcttcaa atcacgtcaa tatcgccttg ccgtatatgt aggatactga ctacgtcagt
    19861 tccatctaca acctcaaaac agtgttttga gcaacctgcg gctagtttcc tagtttgatc
    19921 tttgattttc attgagtatt agtaattcag ttactaactc gtcaactctg atttatccaa
    19981 taaaattgaa aaggatggaa aaaaggataa atttatgata tactttattt tgaagacctt
    20041 attagaaatc ttgaaagagt attgaaaact tagaatgaga aaaattgtta tcaatggtgg
    20101 attaccactg caaggtgaaa tcactattag tggtgctaaa aatagtgtcg ttgccttaat
    20161 tccagctatt atcttggctg atgatgtggt gactttggat tgcgttccag atatttcgga
    20221 tgtagccagt cttgtcgaaa tcatggaatt gatgggagct actgttaagc gttatgacga
    20281 tgtattggag attgacccaa gaggtgttca aaatattcca atgccttatg gtaaaattaa
    20341 cagtcttcgt gcatcttact atttttatgg gagcctctta ggccgttttg gtgaagcgac
    20401 agttggtcta ccgggaggat gtgatcttgg tcctcgtccg attgacttac accttaaggc
    20461 gtttgaagct atgggtgcca ctgctagcta cgagggagat aacatgaagt tatctgctaa
    20521 agatacagga cttcatggtg caagtattta catggatacg gttagtgtgg gagcaacgat
    20581 taatacgatg attgctgcgg ttaaagcaaa tggtcgtact attattgaaa atgcagcccg
    20641 tgaacctgag attattgatg tagctactct cttgaataat atgggtgccc atatccgtgg
    20701 ggcaggaact aatatcatca ttattgatgg tgttgaaaga ttacatggga cacgtcatca
    20761 ggtgattcca gaccgcattg aagctggaac atatatatct ttagctgctg cagttggtaa
    20821 aggaattcgt ataaataatg ttctttacga acacctggaa gggtttattg ctaagttgga
    20881 agaaatggga gtgagaatga ctgtatctga agacagcatt tttgtcgagg aacagtctaa
    20941 tttgaaagca atcaatatta agacagctcc ttacccaggc tttgcaactg atttgcaaca
    21001 accgcttacc cctcttttac taagagcgaa tggtcgtggt acaattgtcg atacgattta
    21061 cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg gatgcggata tttcgacaac
    21121 aaatggtcat attttgtaca cgggtggacg tgatttacgt ggggccagtg ttaaagcgac
    21181 cgacttaaga gctggggctg cactagtcat tgctgggctt atggctgaag gtaaaactga
    21241 aattaccaat atcgagttta tcttacgtgg ttattctgat attatcgaaa aattacgtaa
    21301 tttaggagcg gatattagac ttgttgagga ttaaaccgta gaggtgttta tgaatatttg
    21361 gaccaaatta gcaatgtttt ctttttttga aacggatcgc ttgtatttgc gtcctttctt
    21421 ttttagtgat agtcaggact tccgcgagat agcttcaaat ccagaaaatc ttcaatttat
    21481 tttcccaacg caggcaagtc tggaagaaag tcaatatgca ctggccaatt actttatgaa
    21541 gtcccctttg ggagtgtggg caatttgtga ccagaaaaat caacaaatga ttggttctat
    21601 taaatttgag aagttagatg aaatcaaaaa agaagctgag cttggctatt ttttgagaaa
    21661 agatgcttgg tcgcaaggat ttatgacaga ggttgttaga aaaatttgtc agctttcttt
    21721 tgaggaattt ggcttaaaac aattatttat cattacccac cttgaaaatg aagctagcca
    21781 aagagttgct cttaagtctg gatttagttt gttccgtcag tttaagggaa gtgatcgtta
    21841 cacaagaaaa atgcgggatt atcttgaatt tcggtatgta aaaggagagt tcaatgagta
    21901 agcatcagga aattctaagc tatttggagg aattaccagt aggtaaaagg gtcagtgttc
    21961 gtagcatttc gaatcatcta ggagttagtg atggaacagc ctatcgagct attaaagaag
    22021 ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg aacaattcgt gttaaatccc
    22081 agaaagttgc tatagataga ttaacgtttg ctgaaattgc agaagtgact tcttctgagg
    22141 ttctggctgg gcaagaaggt ttagagagag aatttagtaa gttttcaatt ggtgccatga
    22201 ctgaacaaaa tatcttgtct taccttcatg atggggggct cttgattgtc ggagaccgaa
    22261 cccgtattca gttgctagcc ttggaaaatg aaaatgcagt tctggttaca gggggatttc
    22321 aggttcatga tgatgtgctt aaactggcca atcaaaaagg gattcctgtt ctaagaagta
    22381 agcatgatac ctttaccgtc gctaccatga tcaataaagc cttgtcaaat gtccaaatca
    22441 agactgatat tctgacagtt gagaaacttt atcgccctag tcatgagtat ggttttctga
    22501 gagagacaga tacagttaaa gattatttgg acttggttcg taagaatcgt agcagccgtt
    22561 tccctgttat caatcaacat caggtcgttg ttggcgttgt aaccatgaga gacgctggtg
    22621 ataaatcacc aagcacgaca attgataagg ttatgtctcg tagtctattt ttggttggat
    22681 tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc agaagacttt gaaatggtac
    22741 cagttgttcg aagcaatcaa actttgcttg gcgttgtgac gcgacgagat gtcatggaga
    22801 agatgagccg ttcccaagtt tcggctctac caactttttc tgagcagatt ggacaaaagc
    22861 tctcttatca ccatgatgaa gtagtcatta cagtggaacc ctttatgcta gaaaaaaatg
    22921 gagttttggc taatggtgta ttggcagaaa ttctgaccca catgacccaa gatttagttg
    22981 ttaatagtgg tcgcaatctc attatcgagc agatgctgat ctactttttg caggccgttc
    23041 agatagatga tatattgcgc attcaggcac ggattattca tcatacgaga cggtcagcta
    23101 taattgatta cgatatttat catggtcacc agattgtttc aaaagcaaat gtgactgtta
    23161 aaattaatta gaaactagga gaaaagatga taacattaaa atcagctcgt gaaatcgaag
    23221 ctatggacaa ggctggtgat tttctagcaa gtattcatat aggcttacgt gatttgatta
    23281 agccaggcgt agatatgtgg gaagttgaag aatatgtccg ccgtcgttgt aaagaagaaa
    23341 atttccttcc acttcagatt ggggttgacg gtgccatgat ggactatcct tatgctacct
    23401 gttgctctct taacgatgaa gtggctcacg ctttccctcg tcattatatc ttgaaagatg
    23461 gtgatttgct caaagttgat atggttttgg gaggtcccat tgctaaatct gacctaaatg
    23521 tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa atacactcag agctattctg
    23581 gtggtttagc agactcatgt tgggcttatg ctgttggtac accgtccgaa gaagtcaaaa
    23641 acttgatgga tgtaaccaaa gaagctatgt acaagggtat tgagcaagct gttgttggaa
    23701 atcgtatcgg tgatatcggt gcggctattc aagaatacgc tgaaagtcgt ggttacggtg
    23761 tagtgcgtga tttggttggt catggtgttg gcccaactat gcacgaagaa ccaatggttc
    23821 ctaactatgg tattgcaggt cgtggactcc gtcttcgtga aggaatggtc ttaaccattg
    23881 aaccaatgat caatacaggc gattgggaaa ttgatacaga tatgaaaact ggttgggcgc
    23941 ataagaccat tgacggtgga ttgtcatgtc agtatgaaca ccaatttgtc attacgaaag
    24001 atggacctgt tatcttgact agccaaggtg aagaaggaac ttattaataa aaagtgaaaa
    24061 gactactgga agtttatttt gataaaaaat ccagtagatt ttttcataat aaaacgcatt
    24121 gtatcaagtg ttaggggctg atatcatgcg tttttctgct tttaagattt tttccaactc
    24181 tgtttgtaag cgcatcataa caaagggtct aggattcagg gctctcctcc tatatactat
    24241 tagtaaagta aaactaaggg aggatatttt agtgtcgcag tctattgttc ctgtagagat
    24301 tccacaatat tgtcgttttg attctaaaaa gagaaatgga attctgttta acgttcgtat
    24361 tgccaatctt aaatttattt ttttatatta gact
//
LOCUS       DAVLIK010000030        24145 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLIK010000030 DAVLIK010000000
VERSION     DAVLIK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24145
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.030"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(39..236)
                     /gene="blpI"
                     /locus_tag="VXE87_001336"
     CDS             complement(39..236)
                     /gene="blpI"
                     /locus_tag="VXE87_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV0842871.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            518..1105
                     /locus_tag="VXE87_001337"
     CDS             518..1105
                     /locus_tag="VXE87_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV0842872.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLR"
     gene            1032..2675
                     /locus_tag="VXE87_001338"
     CDS             1032..2675
                     /locus_tag="VXE87_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0842873.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2686..4047
                     /locus_tag="VXE87_001339"
     CDS             2686..4047
                     /locus_tag="VXE87_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0842874.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGENRI
                     PTGTEIAQVFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4104..4259
                     /gene="blpC"
                     /locus_tag="VXE87_001340"
     CDS             4104..4259
                     /gene="blpC"
                     /locus_tag="VXE87_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0842875.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGWWEELLHETILSKFKITKA
                     LELPIQL"
     gene            complement(4301..5641)
                     /locus_tag="VXE87_001341"
     CDS             complement(4301..5641)
                     /locus_tag="VXE87_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0842876.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLAQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKAFKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5655..6392)
                     /locus_tag="VXE87_001342"
     CDS             complement(5655..6392)
                     /locus_tag="VXE87_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0842877.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6397..6735)
                     /locus_tag="VXE87_001343"
     CDS             complement(6397..6735)
                     /locus_tag="VXE87_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0842878.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7012..7341
                     /locus_tag="VXE87_001344"
     CDS             7012..7341
                     /locus_tag="VXE87_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0842879.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7509..8558)
                     /locus_tag="VXE87_001345"
     CDS             complement(7509..8558)
                     /locus_tag="VXE87_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842880.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8555..9286)
                     /locus_tag="VXE87_001346"
     CDS             complement(8555..9286)
                     /locus_tag="VXE87_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842881.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMLRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9354..9764
                     /locus_tag="VXE87_001347"
     CDS             9354..9764
                     /locus_tag="VXE87_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0842882.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQIAETIKNA"
     gene            9774..10061
                     /locus_tag="VXE87_001348"
     CDS             9774..10061
                     /locus_tag="VXE87_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842883.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10223..10462
                     /locus_tag="VXE87_001349"
     CDS             10223..10462
                     /locus_tag="VXE87_001349"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842884.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHGKPTLTWFEEIFEEYYSPFHN"
     gene            complement(10796..11932)
                     /gene="dnaJ"
                     /locus_tag="VXE87_001350"
     CDS             complement(10796..11932)
                     /gene="dnaJ"
                     /locus_tag="VXE87_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0842885.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRGKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12334..12690)
                     /locus_tag="VXE87_001351"
     CDS             complement(12334..12690)
                     /locus_tag="VXE87_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV0842886.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12692..14515)
                     /gene="dnaK"
                     /locus_tag="VXE87_001352"
     CDS             complement(12692..14515)
                     /gene="dnaK"
                     /locus_tag="VXE87_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0842887.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAESDKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15004..15528)
                     /gene="grpE"
                     /locus_tag="VXE87_001353"
     CDS             complement(15004..15528)
                     /gene="grpE"
                     /locus_tag="VXE87_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0842888.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15555..16589)
                     /gene="hrcA"
                     /locus_tag="VXE87_001354"
     CDS             complement(15555..16589)
                     /gene="hrcA"
                     /locus_tag="VXE87_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0842889.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16753..17262)
                     /locus_tag="VXE87_001355"
     CDS             complement(16753..17262)
                     /locus_tag="VXE87_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0842890.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17867..20200
                     /locus_tag="VXE87_001356"
     CDS             17867..20200
                     /locus_tag="VXE87_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0842891.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20213..21676
                     /locus_tag="VXE87_001357"
     CDS             20213..21676
                     /locus_tag="VXE87_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0842892.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21676..23244
                     /locus_tag="VXE87_001358"
     CDS             21676..23244
                     /locus_tag="VXE87_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0842893.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLAEQQRIIEAIESALEKVDEYAESYNRLEQLDKKFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHINALI"
     gene            23301..24098
                     /gene="psrA"
                     /locus_tag="VXE87_001359"
     CDS             23301..24098
                     /gene="psrA"
                     /locus_tag="VXE87_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV0842894.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT         7755 a         4782 c         4451 g         7157 t
ORIGIN      
        1 taatagcgat aataatacta tatttaagaa tcataatctt acaaagagga cataattcct
       61 gaacctacac aaataagtgt tgctgctccc ccagttatcg gaccagtcgc agcagctaat
      121 agtactgctc caatacaacc accgattgca gatcctaaat tgcctcttcc tccactaact
      181 atttcgagtt cttcattatc cataacagaa aattgttcca tcatttttgt attcatgaca
      241 aatactcctt ttttcttttt ttatttttgt cttgttgtaa ctttgataag tttagtatat
      301 catcgttttt taaaattttt catccagatc ttgaattgtc atcgaaacgt cttgaattag
      361 cttttttatt tcaagccacc tctaaatgtt taaaaaaaat aatttctaat cactttttta
      421 ccattcagga agttttaatg actattcaag atttcataaa atatgaactt agttttatga
      481 cataatagac ctatccacta tatgaaagga attgccaatg acttcttata aacgtacatt
      541 tgttcctcaa atagatgcga gagactgtgg tgtcgctgcc ttagcctcga ttgctaaatt
      601 ctatggttca gatttttctc tagctcactt gagagaactt gcaaagacca ataaagaagg
      661 gacgactgct cttggcattg taaaagccgc tgatgaaatg ggctttgaaa caagacctgt
      721 tcaagcagat aaaacgctct ttgacatgag tgatgtcccc tatccattta tcgttcacgt
      781 taacaaagaa ggaaaactcc aacattacta tgttgtctat caaacaaaga aagactatct
      841 gattattggt gatcctgacc cttctgtaaa aatcactaaa atgtcaaaag aacgcttttt
      901 ctatgaatgg actggagtag ctatttttct agctaccaaa cccagctatc aaccccataa
      961 agataaaaag aatggtctac taagcaagct tccttcctct gattttcaaa caaaaatctc
     1021 tcattgctta cattgttctc tcaagcttat tggtcactat tatcaatata ggtggttctt
     1081 actatctcca aggaatctta gatgaataca tcccaaatca gatgaaatca actttaggaa
     1141 tcatctcagt tggtctggtt atcacctata tcctccaaca agtcatgagc ttctccagag
     1201 attatctcct aaccgttctg agccagagat taagcattga tgtgatttta tcctatattc
     1261 gccatatttt tgaacttccc atgtctttct ttgcgacacg tcgtacagga gaaatcattt
     1321 cacggttcac agatgctaac tctattatag atgccttggc ttctaccatt ctttctcttt
     1381 ttctggatgt ttctattctg attcttgtag ggggagtctt gctggcacaa aaccctaatc
     1441 tcttcctcct ttctcttctt tccattccta tatacatgtt catcatcttt tcttttatga
     1501 aacctttcga aaaaatgaac catgatgtca tgcaaagtaa ttctatggtt agctctgcca
     1561 ttatcgaaga tatcaacggg attgaaacta taaagtcgct cacgagtgaa gaaaatcgct
     1621 atcaaaatat agacagcgaa tttgtagatt atttggaaaa atcctttaag ctcagtaaat
     1681 attctatttt acaaacgagt ttaaagcagg gaacaaaatt agttctgaat atccttatcc
     1741 tatggtttgg cgctcaatta gtcatgtcaa gtaaaatttc tatcggtcag ctgattacct
     1801 ttaacacact tttttcttac tttacaactc ctatggaaaa tattatcaac ctccaaacca
     1861 aactccaatc tgcgaaggtc gctaataacc gtttgaacga agtctatcta gtcgaatctg
     1921 aatttcaagt tcaagaaaac cctgttcatt cacatttttt gatgggcgat attgaatttg
     1981 atgacctttc ttataagtat ggttttggac gagatacctt aacagatatt aatctcacga
     2041 ttaaacaagg agataaggtt agcctagttg gagttagtgg ttctggtaaa acaactttag
     2101 ccaaaatgat tgtcaatttc tttgaaccct acaaagggca tatttccatc aatcatcagg
     2161 atattaaaaa cattgataaa aaagtcttgc gccgtcatat taattaccta ccccaacaag
     2221 cctatatctt taatggctct attttggaaa acttaacctt gggcggtaat catatgatta
     2281 gtcaagaaga tattctaaaa gcttgtgaag tagctgaaat ccgtcaagac attgaaagaa
     2341 tgcctatggg ctatcaaact cagctctctg atggagctgg tctatcagga ggacagaagc
     2401 aacgaatcgc tctcgctcgt gctcttttaa ctaaatctcc tgttttaata ctagatgaag
     2461 ctactagcgg tcttgatgtc ttgactgaga aaaaagttat agataatctt atgtccctaa
     2521 ctgataaaac cattctcttt gtagcccatc gtctcagtat agccgaacga accaaccgtg
     2581 tcattgttct tgaccagggg aaaatcattg aagttggtag ccaccaagag ttaatgcagg
     2641 cgcaaggttt ctaccatcat ctattcaata aataaggaga atgtcatgaa tcctaatctt
     2701 tttagaagcg tcgagtttta tcagagacgt taccataact atgcgacagt gttaattata
     2761 cctctttcat tactatttac tttcatcttg attttctccc ttgttgccac aaaagaaatt
     2821 actgtcactt cccaaggaga aatcgcccct acaagtgtca tttcatctat tcagtcaacc
     2881 agtgataatc ctatccttgc taatcattta gtggcaaatc aagtagttga aaaaggggac
     2941 ttactcatca aatactctga aacaatggaa gaaagtcaga aaactgcctt agcaactcaa
     3001 ttacaaagac ttgagaagca aaaagaagga cttggaattt tgaaacaaag cttagaaaaa
     3061 gcgactgatc ttttttctgg cgaggatgaa tttggctacc ataatacctt tatgaatttt
     3121 actaaacaat cccatgatat tgaactgggt atcacaaaga ctaacactga ggtttcaaat
     3181 caagctaatc ttgccaatag cagttcatca gctattgaac aagaaattac aaaagttcaa
     3241 caacaaattg gagaatatca agagctgaga gatgctatca taaataacag agcacgctta
     3301 ccaactagca atccacacca gtcaattttg aatcgttatc ttgtagcctc acaaggacaa
     3361 acacaaggaa cggcagagga gccattttta tctcaaatta atcaaagtat tgcaggtctt
     3421 gaatcatcta tcgcaagcct caaaattcag caagctggta tcggaagtgt agcaacttat
     3481 gataatagtt tagcaaccaa aattgaagta ctccgcactc agtttttaca aacagcctca
     3541 cagcaacaac taaccgtgga gaaccaatta acagaattaa aagtacaact agatcaagcg
     3601 acacagcgct tagaaaacaa taccttaacc gctccaagta aaggtatcgt tcatctgaac
     3661 agcgaatttg aaggtgaaaa tagaattcca actggtacag aaattgctca agtattccct
     3721 atcatcacag atacaagaga agtactaatc acttactacg tagcttctga ctatctacct
     3781 ctactagata aaggacaaac tgtaagatta aaactggaga agattggaaa tcacggcatt
     3841 accatcatcg gccaacttca gacaattgat caaactccta ccagaacaga gcaaggcaat
     3901 ctctttaaat taaccgctct tgcaaaacta tctaatgagg atagtaaact catccaatat
     3961 ggcttacaag gtcgcgtcac tagtgtaact gcaaagaaaa catattttga ttatttcaaa
     4021 gataaaattt taacccattc tgattaattt tcagataaca ctctataact atttattatc
     4081 ttatcaaaaa ggagaatcat aacatggata agaaacaaaa cctaacttca tttcaagaac
     4141 taacaactac cgaactcaac caaattacag gtggaggatg gtgggaagaa ctcttacatg
     4201 aaacaatttt aagtaaattt aaaatcacaa aagcacttga actacctatt cagctataaa
     4261 aacaagaccg agaaacaagt actctcggtc ttatttttca tcattctgta tgtatcacag
     4321 taagtacctg acgaaagact tgattttgac aggtggtatt tagactggta ttaggatggc
     4381 tttccacaat cttcatgacg gtatagagac caactcctct ctcctcccct ttagaactgg
     4441 ctccaaagga gaagatttca gaaatatcga tgccctcttc tttgatggag ttttcgatga
     4501 taaaggtctc ctgtgctcca ttttttaaaa aggcgattga aacatgaggt tgactagctt
     4561 ccacactggc ttcaatagca ttgtcacaaa ggatagacac aatggttaga aaatcaagta
     4621 gactcatccc ctcgacctga atctcctcag gaacttcgac attaaagaca atgttcttat
     4681 ctctggcttt taaaaatttc cctgctagaa gacttttgaa ggctttatca cgaatattta
     4741 ccaatctgcc caggtcatat ttattgttct gcaatttctg actggaatcc tttaagacgg
     4801 agccatagac ctcttttatc tgctccatat cctcctcttc aatgcccaga cgtaagctag
     4861 tcaagaggtt ggtataatca tggcgaaaac tccgtacttc cttgtaaagc tcctctatat
     4921 gccgactata gcgttccata tctctatagc gcagggcctg ctcttgttcc aatctctcat
     4981 agagtttttc cttcaaatag gtatccaatt tcttgataac ccccataaaa aagagtaggt
     5041 aaaagactag gatgagatgg cgaacagtct ttgattgaat actttgttca tattcaaaaa
     5101 aagacagact ttccatgact agatagtagc cacccattat ccagttaatc tgagccaggg
     5161 acttttgaaa ggctttatcg agaatctcct ttctcaagct agtaaaatcg tagtccaacc
     5221 atttcaaaaa agctagagaa atgaagaaat tgaaaattat tatacataac ccagtaaatg
     5281 agtagccatc atatacttgc ccttgtccca aaaatggaag cacaaaatag gagactcctc
     5341 tataaaagag attcaccaat atcattggaa agagaccata aaagaaaagg agttttttag
     5401 gaagccctct caataataag aaagataagc ctatgccgta caagggttcc ataaaataag
     5461 ataggtaaac atttcctact atatagctaa tcatcacaaa aacaaaggcc aacagtatct
     5521 taaaaagaaa ggccttaaaa atcctctcga aagtaagatc aattccatcc accttaaaga
     5581 agatgacaat ttctagtcca ttagtaacaa gtgtatacaa caatatccaa gcaatgttca
     5641 taaattctcc tagctcagtg taatttattg atggcctcag acacttccct gaccttataa
     5701 cgggcgatta gacaacttcc accattggga aagaaaagca gtttttcttt cttatccaaa
     5761 tgcaccacat ttgcaggatt gatgagaaaa gagcggtggc actgcaagag acggggctcc
     5821 tgcttgaaaa cctcctctaa actcgctgta aattccagcc tgtctgtctt ggtatagaga
     5881 ataacacgat gggctctggg cgacgtttcg agatagtaaa cctctttaaa aggatactga
     5941 aattgggcaa attttgattt aaagtaaaag caatcttccg ccagactttt actatcttga
     6001 ctattggcat agaggagggc tgtctcgatc cgagattcaa actcctctgc tgacaaggcc
     6061 ttatcaatgt agtccaaagc agacacttgg tagcgaaaag acaggggcat aaactccgag
     6121 tgagtcgtca caaagacaat cagggcataa ggatcccgat cccgaatctt tctagccact
     6181 tccagtccct tcatctcttc atttcgaatc tcaatatcca aaaagaatag ctgatgggcc
     6241 cccttctcat gcacttcagc cagcagttgg tccggcttgc caaatacctc aaaagagcta
     6301 ggaatgatat gatgtgcttt caaaagtttc tcaatcgtcg tttcaattct agtctgttgg
     6361 gaaaaatcat cctctaaaac aaatattctc atcttcttac tctccctctt tcaaccattt
     6421 ttgacgaatt tctctatagc gacgtctggc atacttgaca gcgtattgac cttcttctcc
     6481 gagaaaaagg attctttctt gaaaatcaat cgattttaat ttatcaagat taaccaaaca
     6541 atttcgatga catctcatca aggtttcccc acattggttc tcaagattac ttaaattttg
     6601 aagcatatta aaactagctt tttctgtaac aatctgtacg gtatgggctt tagttggatg
     6661 tgtttggata tagtagatat cgtcgacgtt tactttatag actgttttct gcgtctgaat
     6721 aatcatatgt ttcattggat tctcctccta agaaaagaat aacagaaaag ttctagccca
     6781 agcccaccca atcctaaaca gtctttgaaa gctcctaaaa ggattatttt tctacaacat
     6841 catgatgagc ttacaactat tttatcataa aattcactca gcgcaattca agacatttca
     6901 atgacaatta aagatttgaa taaaaaaaaa gaattaaaag tgataaacta acagtatcaa
     6961 aacacagttg ccagaagtaa gactggcacc cagattaaag gaggcattcc catgacagat
     7021 acagacccca tcaaaagagc tcatactttg attactgact taaacaaagc ctaccaagca
     7081 tgcaaacagg caagtgctga cgacgtccgc tttcaggagc aattaaactc tattcttggt
     7141 tttctagcca aggctgaaac agtggataat cgattcttga ttgaactaga aaaattttac
     7201 cagacttcca gtcttctcat gggactcagc gctcttgatc cagatgctcc aactcgcgcc
     7261 gcttggcggg cctatgaccg cttccacttt gaccaagtca agaccaagtt aatactcaat
     7321 gaaaatcaaa gagcaaacta ggaagctagc cgcaagctgt acttgagtac ggtaaggtga
     7381 cgctgacgtg gtttgaagag attttcgaag agtataagtc tctacggacc aaccattatc
     7441 ctgtagtaac aaaaaagaag ctgagacaga ctgaactcaa cttctttttt agtgtcgtat
     7501 cagcaatgtt agtcctgcat ctgacgtttt acctgataag gcaaatacaa gactagtaaa
     7561 accaaaccag ctcctagtaa ggctagaagg gccagttttt cttggaaggt aatcaaccca
     7621 acaactaatt ccacaagtaa aacaaaactg gtcaatcctc gaactacctc ctgtaagcct
     7681 ttttcctttt gccccttgtc cagtggaaag agttgggtca aatactggta gtcaaaggca
     7741 tgatagaggg ccagcaactg aaagagcaag aggtagttaa agagaaccac cactgctgtc
     7801 gcaatccaag cttgctcgat aaaaacctgc gccagtacgg aaagtaagag aagacgaaga
     7861 ctgagagcaa agaggtcgcc atttcgcaga taagaacgca gatagagatt ttgccaaatc
     7921 ttcccaggca ccttctgaac agcctttaag ataaagtcca gataggcacg acgcttgaca
     7981 ctgtttgaaa ttcccttgac ctgcgtaaag agggcaaaga aacgaagcaa gacttgctta
     8041 cgcttgcttt cttgagaaat aagatagtcc cagtccagtc cagtttcagt gaaaaatttg
     8101 ctggcctttt gacgaaagtg gaaatatttt cctaccccca ataaaagcac atagagcaga
     8161 aaaactggca agccataacc cattgctaaa aacaagggcg caaataacag caagaaaagg
     8221 gtctgtacaa agagccaaaa gactagggaa atgccagttt gacgcttgag atggagcttg
     8281 atttcctctt ctccaactaa gagaaagagc ttgtctggag cctccatata ggtggcaatt
     8341 cctccccaaa gtaaaagtaa aacagacgta attcctacaa acaaaagaat aggccaatga
     8401 ttttcaggaa aatgttgtaa gagttgactg tactggtagg ctagaaagcc caacaggaca
     8461 agcaggaata agacaaagtg gtcattgagc acatagcgca gataaccaag acactcctta
     8521 cgaaaggcct gctttctctt taaaaacaag tctttcatag gtcctcctct tttgtcagag
     8581 ccaagtaaat atcattcaaa ctagcctcag gcatatcaaa ggcttcgcgt agttgcagga
     8641 gattgccttt ggcacgcacc tctcccttgt gaagaatgac aaaggcatca cacatcttct
     8701 ccgccgaatc cagcacgtgg gtactcatga gaatagactt gcccttttgc ttctccactt
     8761 ccaaaagctg aatcaaatca gaaatagcca gcggatcaag accaaggaaa ggctcatcca
     8821 cgatgaaaag acttggatcc accacaaaag cacagataat catgaccttc tgcttcatcc
     8881 cttttgaaaa atgaacaggg aaccagtcta atttctgttc cagacggagc atctttaaca
     8941 agggctctac tcgttcgaaa gccacttttt gctcaatacc ataagccata gcaaccgttt
     9001 cgatatgctc tctgagggtc aattcctcat acagactagg cgtctcagga atgtagccaa
     9061 tctgcttgcg gtagctagtc gcatctcctt gcagagtcag gccattgata ttgatggagc
     9121 cactataagg tgccaacaga ccgataatct cattgatcgt cgttgatttc ccagcaccat
     9181 tgagaccaat caaaccgacc aactgcccac tttcaacagt aaaggacaca tctttcaaaa
     9241 caggaacatg aacatagcca cctgtcaggt ttttaatttc taacatattt tctccaaatc
     9301 tggtataatg tagctatatt atatcaaaat tcaatacagc agaggtagat tttatgtcag
     9361 attgcatttt ttgtaaaatc atcgcagggg aaattcctgc ttcaaaagta tatgaagatg
     9421 agcaggtcct tgcctttctt gatatctctc aagtaacact aggacacacc ttggtcgtgc
     9481 caaaagaaca ctatcgcaat cttttggaga tggatgctac gagcgccagc caactctttg
     9541 cccaagtacc aaaagtagct caaaaagtca tgaaagtcac taaggctgct ggtatgaata
     9601 tcatttccaa ctgtgaagaa gtcgctggtc aaacagtttt tcatactcac gttcaccttg
     9661 tgcctcgcta cagtgctgac gatgacctca agattgattt tatcgcccac gaaccagact
     9721 ttgacaaact tgctcaaatc gctgaaacca tcaaaaacgc ttaaggagtt gctatgaaat
     9781 tatccaacct actgctattt gcaggagctg cagccggaag ttatctggtt acaaaaaatc
     9841 gccaaaccat cacagatgaa gtcttgaata ccactgaccg cgttcaagct atcaaggacg
     9901 atgtggatat tatccaaaac agcctgcaaa tcattaacca gcaaaaagaa cttatcaagg
     9961 aataccaaga agacttgact tacaagttta aggtcttgga aaaggatatc cagactagac
    10021 tagctgtgat aaaagaaatg cagggaactg aagataagta aaaagagccc cccggctctt
    10081 ttttaaaacg taaacaagtt atagtgaatt gaatttagaa tagcacacca tagtttctaa
    10141 agcattgtta gagattactt taaaatcctc ttatcaattt gttcatattc tatttcaatc
    10201 tattatatat atcccatcaa ctatgcatca taatttaggt aactcatact caataaaaat
    10261 caaaaagcaa actagaaagc taggcacaga ctgctcaaaa caccgtttta aggttgtgga
    10321 tagaactgac gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt
    10381 cagtaaccat acccatggca agccgacgct gacgtggttt gaagagattt tcgaagagta
    10441 ttattcacca tttcacaact aaatcgaaga ctttctgccg taatgaaaac acctgaaaca
    10501 gcttggtttc agctgtccgg aaactttaaa acttaggttc aaagtttagg tatggaactt
    10561 cgcaggaggt cactaccgtc cgtcattact taggaaagtc ttaaaaaatc tataaagtaa
    10621 aaagagcccg acagctcttt ttgtttatac tcaatgaaaa tcaaaaagca aactaggaaa
    10681 ctagccacgg gctgctcaaa acactgtttt gaggttgtag atacgactga cgaagtcagt
    10741 cacatatata cgacaagccg acgctgacgt ggtttgaaga aatttttgaa gagtattatt
    10801 ctccatcaaa ggcatcttta atatggtcaa agaagccttt tttctttgga tttactttca
    10861 agtcaccagc agccgcgaat tctttcaagg ctactttttg gcggtcgttc aagcctgtcg
    10921 gtgttacgac attaacagta acgtattggt caccaactgc accgccacga aggctcggtg
    10981 cccccttacc acgtaggcgg aatttcttac cagtctgagt tccctctgga ataaccaatt
    11041 caacatcacc gtgaacagtt ggaatatcta ctgtatcacc aagagccgct tggacaaagt
    11101 tgaggttgag attgtagaag atagtcgttc cttcacgttc aaacttgtcg ctagcttcta
    11161 cagaaactac tacatacaag tccccataag gtccaccgtt aaagcctgct tcgccttgac
    11221 cagcgaggcg aatttgttga cctgtttcca caccagcagg gattttcaca tgtacgctat
    11281 gagcttgttt ctcatggcct gttccatgac aggttgtaca tggatatttg atttcttttc
    11341 ctcgaccgtg acagacatca caggttactt ggcgacgcat cataccaaga ggagtctgcg
    11401 tatcgacgtt aatgacacca gcgccatgac agcgtccaca agtgactgga cttgtccctg
    11461 gcttagcacc agagccatta catgtacgac agccagcttc acgatgatac ttaacttcct
    11521 tctcagttcc gaagatagct tcttcaaagg tcaaattgac acgatactgg agatcatctc
    11581 cttggcgagg agcgtttgga ttgcgcgaag aaccgcctcc gccgaagaaa cttgagaaaa
    11641 tatcctcaaa accaccgaag ccacctgccc cattgaaacc accgaaacca ccagctccac
    11701 caaaaccacc attggcgcct gcagcaccat actggtcata ggcagcacgt ttttggtcgt
    11761 cactcaaagt ctcataggct tcttgaactt ccttgtactt gtcctcagca ccaggctcct
    11821 tgttgatatc tgggtgatat tttttggaaa gcttacgata agcctttttg atttcgtctg
    11881 ccgaagcgtt tttggatacc cccagacgat cataaaattc agtattgttc ataattcaag
    11941 atacaaaggg cgtcaaacgg acacagccat ctaggagttt tgacgacgga cgcttacgtc
    12001 ctagaaaaaa ctatcttttt ggcacagtcc gtagcccgtg ttcagttacg aacaccctta
    12061 ttcctttcta ttgatgttct gaatcgaacc accatttagg tcgggttcaa ttcctttctt
    12121 ttatatttag taagaaattc tgaaacccgt gttcagttac gaacactctt tgttcctttc
    12181 tattgatgag acaaaaccca aacaaatgag attccgtccc tttttatcga aaaacagagg
    12241 ctgggttgca acctctgcaa ataagtaaat taactttatt ttgattttaa atatcctata
    12301 agtacagaaa tatttatata tttttgtctc ttcttagtat ttgcctatat aattccaatt
    12361 gatcataaga aatacaacta ctgtccaaat cataccaatt atgaacggta ttacaaattt
    12421 atatgtttgt atttctaatg atatcatagc tgataccatc gccgatacaa atgcagacaa
    12481 caatactgag gtaacaaaat tccttaccgc ttcatcattt ttgacacaac tatcatgctc
    12541 agctaatata atttctctat atctagctaa atattctatt ggaatattat caataaaatc
    12601 ttttgatgtt ctatagttat cagcttgatt acaaaaatca ttataaactt ttcgtgtatt
    12661 ttttagatac tcttcatcca atacactcat cttacttttc cgtaaactct ccgtctacga
    12721 cgtcatcgcc tgcgtttcct gttgcttgtg cgccttctgc tccttcttga gcttgttgcg
    12781 ctgctgcggc ttgttcgtag agtttaacag caagtccttg agctttttcg ttcaatgctt
    12841 caagttttgc tttcatgtcg tccaagttgt tgtcttcttg agctttctta aggtcatcaa
    12901 gggcagcttg ggcagcgtca cgttctgcgt cgaagccttt accttcagtt tccttgattg
    12961 tcttttcagt cgcaaagatt gcttggtcca cttcattacg aaggtctact tcttctttac
    13021 gtttcttatc ggattcagcg tttgcttctg catctttcat catgcggtcg atttcttcgt
    13081 cagtcaaacc tgagttcgat tggatgacaa tagtttgttc tttttgagtt ccaaggtctt
    13141 tggccttaac agacacgata ccgttcttgt cgatgtcaaa tgttacttcg atttgaggaa
    13201 ttccacgagg tgcagctggg atatcagtca attggaagcg tccaagagtc ttgttatctg
    13261 ctgccattgg gcgttcacct tgaagaacgt ggatatcaac ggctggttgg ttgtctgctg
    13321 ctgttgagaa gacttgtgat ttagatgttg ggattgtagt gttgcgatcg ataagttttg
    13381 taaatactcc acccattgtt tcgataccaa gtgacaatgg cgttacatca agaaggacaa
    13441 catccttgac atcaccagta atcacaccac cttggatagc cgcacccata gcaactactt
    13501 catcagggtt tactgatttg tttggttctt taccagtttc agctttaaca gcttcaacaa
    13561 cggcagggat acgagttgaa ccaccaacaa ggataacttc gtcgatttct gacaagctca
    13621 aacctgcatc tgaaagggct tgacgaactg gaacttttgt acgttcaaca aggtcacgag
    13681 tcaaatcatc aaatttcgca cgagttaaag tcatttccaa gtgaagaggt ccagcctcac
    13741 ctgcagtgat aaatggcaag ctgatttgtg ttgaagttac accagaaagg tctttcttcg
    13801 ctttttcagc cgcatctttc aaacgttgca ttgccatctt gtcagtagac aagtcgatac
    13861 cgttttcttt cttgaattct gctaccaagt ggtcaatgat tttttggtca aagtcgtcac
    13921 caccaagttt gttgtcccct gcagttgaca atacgtcgaa gacaccgtca cccaattcaa
    13981 ggatagagac gtcgaatgta ccaccaccaa ggtcaaatac caagattttt tcttctttgt
    14041 cagtcttgtc caaaccataa gcaagagctg ctgcagttgg ttcgttaaca atacgttcta
    14101 cttcaagacc agcaatttta ccagcgtctt ttgttgcttg acgttgagcg tcgttgaagt
    14161 aagccggaac tgtgataaca gctttggtta ctttctcacc aaggtagtct tcagcgtagc
    14221 ctttcaagta ttgaaggatc atagctgaga tttcttgtgg agtgtattct tttccatttg
    14281 cagaaacttt ttcagaagtt cccatcttag atttgataga gataactgta tctgggtttg
    14341 tgactgcttg acgttttgca gcatcaccaa cgatgatttc tccgtttttg aatgagacta
    14401 cagatggagt tgtgcggttt ccttctgggt ttgcgatgat tttgctttca gttccttcaa
    14461 gaactgcaac tgctgagttt gttgtaccta agtcaatacc gataatttta gacatgtgtt
    14521 tttctccttg ttagttaatt ttctattttt ctttttgata ctcttcttaa gtggcgacag
    14581 tggcgacgcc gtcagagctt gacttcgtca gtctctttga ctaaactttg agcctaaggt
    14641 ctcaaaattt gcgcaaatag cgccacggcg aagagtatcg tctttggttc gcttcgctca
    14701 ctattacaaa gcaaaacata ttttatcttt cttcatagtt tattgtcgtt tcggacaagt
    14761 tttctattat gtaaattgcg acacgaggag tcgaaatcga ttttatttcg acgacgagtt
    14821 agtaaggaag ctaggcaaac gccatagcaa ttgccgtttt ctgacgagtt gctttagcta
    14881 ccgtcagaat tgccgaatcg aacacgccct aagctctgag taaaaaagat agattttctt
    14941 gtgttcatcg aacacttcgt taatctccta tttttactgc gagcttttta cgggctttgt
    15001 atcttagtta tacaccacta ccattgctgg gcgtaggatg cggtcatgga gtttgtagcc
    15061 tttttgaaag acttgggcga tggtatctac tgggtgttca tcgtctgctg ggagagtttg
    15121 gatggccata tggtagttat ggtcaaattc gccatctgct gcgatttctt caattccttc
    15181 ttctttcaaa gcgtgaatca agctttcttg caccatcccc aagcccttct tcacatcatc
    15241 tgtcaaacct tcaactgcaa gtgcacgctc aaggttgtca agagatggta agattgcttt
    15301 tgccaagtcc tggctacgat aacgttgcaa gttttgacgt tcttcattgg cacggcgttg
    15361 gatattttgc atttctgcat gagcgcgaag atatttgttt tcgaactcat ctgcacgttc
    15421 atttgccaag tccaactcag acttttcagg agttgtttct tcagctgttt ccacaacttc
    15481 ctcttcttga acttcttcta cttcttcatt ttttatatct tgggccatgt tcgcctcctt
    15541 taatgatttc aatcttaatg tacttcgtaa tgattactgc tgaggtagcg gtaaaaatct
    15601 gtcaacttca tggtcaaaac acggttgacc acattgattt gattgattag ctgttggtaa
    15661 tccagattaa ctggaccgat aatggctaga attccaactc cccgataagg aatgaggaac
    15721 ttactactaa tcaccgctag gtcagctaaa caggactctt gaccgtctgc aacacgaaca
    15781 ttttgcatct gatcctcacg caacccctca cgaatctcca aggccacctt ttgcggttgg
    15841 tcaaagaact gataggctgc tagattggca aaattcaaga gattgacctt gcccgccatc
    15901 acaatgtttt cgttgaacat ttccttaaag atgtgttcaa agagatcgat gacattatcc
    15961 gttgttgtaa agtaacgctg gataatctgc ggaatctccg tccgaatctt gtagtgaata
    16021 tctaaaacgg tgtgaccgag gaaacgttcc tgaatgatgc tcttcagttt cagcaaatcc
    16081 tcctgcaaga agttccttgg aatcagaaac tgactagtaa ccgttcgcga ctcgtctagg
    16141 gtaaataccg ccaaggctgt atgttgcccc aaaacaacga tatcaaaggc tgtcaaacgt
    16201 tgcctgctcg gctcaacatc cagtgccact accgtacagc cactcaggtc tgttagcaag
    16261 ttagcagcct cttgcagaat atcctccaat ttgaagaatt cctgatcaaa ggctttgaca
    16321 atctcatata cctcattttc agccagtcgg tcaaaatcca gtgagtgttt cacatagtac
    16381 tgaaaaccag caacacttgg catccgaccg cttgaagtat gagccttctc aagcaaccct
    16441 tgtttttcta gttccgccat gtcattacga atggttgcac tgctagagtt aatagactct
    16501 tgcaaggctt ttgatccgac aggttcgtgc gttttggtaa agatgtcaat aatcagattt
    16561 aaaatatcct gctgacgctc tgtaaccatc tcatcactcc tctctgtctg atcaattagc
    16621 actcaatgca tccaagtgct aacttatgat tctattatac acccttagaa gagaatgtca
    16681 agacaaaaac tcaaaaaatt agcactcttt tataaagagt gctaaaaatc aatctgaaga
    16741 cctagaacct tgctattcat ctactcggta tttccttttt agtctgaaat aaccatgaat
    16801 tagataagaa atcagaaaag catataaaac aaaaataaga aagaaagaca tagaaagatc
    16861 ctctctaaac aaactcatac aaacaacaag accacctaag aaagtagcta tacaggaacg
    16921 aagtctagat cgcataactt cccatttgag ccccttactc atatagactt gatcctctgg
    16981 aagtaaatca gaagacgatt tacgaagaat cgaacaagaa cctgctccta tcaattccca
    17041 acctctatct ctaaaatctt gcagttcacg cttatgctct ttaagaaatc tagaatcata
    17101 gatacgatag ataacatcgt ccggttgacc ttgctcaaaa tagaacaaac caaaacgact
    17161 agttctatac ctccaacctt tcaaatgcat ctcatgtaaa tattcttctt tcttgtccaa
    17221 atcaacaatg gtgaaaatcc gaaattctac tctgctattc attgtcttac cccaaaatta
    17281 gaaaacatgc ctagcgttat ttattagata attctttcca cttttgactc aatctccaaa
    17341 aaatataaga aatctgaatc gcaaaaacta tcaataaaac ccaatctatt atgaaaatca
    17401 aaaacacttc ccaactgaaa gaactacctc cagtgacaaa ctttgagaaa aacggtagta
    17461 gagctaaaaa gagaagcaaa ataggaagca tccgcattgt taaaatccgt ttggcataaa
    17521 aaatctttat ttaaacgaaa atattatggt aaaatttacg ccagtttttg aacggctgat
    17581 gtagatattt tatactttca aaatgtttaa atgtgattat ttatttttga aaaatagctc
    17641 accagcccga ctgaaagtgc ttataaatga taataagtcg cctgccgaaa acagcgaaaa
    17701 atagcggtgt tatgcggaga taatctgacg cgatgcgaaa gtatattgca tacttatttt
    17761 caacaattta gcagagtatt tttataagtg tgatataata gaagtataat ttgttctgat
    17821 agtttattta tggagaagta gatttttaga atgcggaggg ttcaatatgg ttgagtttat
    17881 aaagtctaag aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat
    17941 tgtatccaaa ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg
    18001 tcgaattgag gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc
    18061 actgtattac caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag
    18121 cgttcgagca ggattacaac aagctattga atatggagag attttagatg ttccatttgt
    18181 ttattcttcg aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga
    18241 gctggagtta gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa
    18301 aggattgacg tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc
    18361 aatgaaaacg ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc
    18421 cagaggacaa aaacgagtaa tgtttgtgat ggcaacagga acggggaaaa cgttcatggc
    18481 ttttcaaatt attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc
    18541 ggatagaaac atcttagtag accaaacgat ggctgaagac tttaggccat tcgaaaaggt
    18601 aatgacgaaa attacaccaa aacttttgac tgctcctgaa aaattaaatt cttttgaaat
    18661 ttatctaggg ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa
    18721 atttgacaaa gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa
    18781 ggaagacagt aactggcgta aggtgattga ttatttcagt tctgcgacac agattgggat
    18841 gaccgctact cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtgagccaat
    18901 ctatacttat agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat
    18961 gagggttaat ttagatgtgg atgtggatgg ttatcgtcca gaaactggaa aagttgatac
    19021 taacggacaa ttaatagaag ataggtacta cggcaggaaa gattttgata aaaccattgt
    19081 cattgatgat agaacgcaaa gagttgccaa gtttgtttct gattatatga agcaaaacaa
    19141 tgcacgattt gataaaacaa ttgttttttg tgttgatatt gaccatgccg agcgaatgcg
    19201 tgctgcactt gtaaaagaga atctagactt agtccaagaa gactatcgtt atgtcatgca
    19261 agtaactggt gacaacgctg aaggaaaagc tcaactggat aactttatgg atgtcaattc
    19321 taattttccc gctattgtaa caacgtctaa attattaacg acaggagtta atgctaaaac
    19381 atgtcgtttg attgttttag actctaatat ccaatccatg actgaattta aacaaattat
    19441 tggtcgtggc acacgtcttt atcctcaaaa ggggaaagaa ttttttacga ttattgattt
    19501 tcgaaatgtt accaatttgt ttgctgaccc tgattttgat ggtgagccag tgaaggtgct
    19561 ggaaacaggt gcgaaaacag tcagtggttc cacgcccggt ttcgtagatg aggaaggtga
    19621 cccagtagaa aaatatatcg ttacagacaa gcaggttacc attcttaatt ctactgttca
    19681 agtattggat gaaaacggga aactgattac cgaaagcctg accgactaca ctcggaagaa
    19741 tatcttaggt agctacgcca ctttgaacga ttttatcaca gtttggcata cggcggataa
    19801 aaagaagctt atcttagacg aactttataa aaaaggagtt tatctagatg ctattcgaga
    19861 gtcggaggga atatcagaac aagaaatcga tgattttgat ttactcctaa aacttgccta
    19921 tggtcaaaaa gaattaacca aaacggaacg tatcaataaa ctcaaacaaa gcggatattt
    19981 atataaatat agtgaggaag cgcgtgctgt tttggaaatt ttactgaaca aatacatgga
    20041 taaaggtatt ggagaactcg aaagcattga aacattaaaa cttccagaat ttcagatata
    20101 tggtggaacc ttcaaaatca tcaatactta ttttggagat aaaaaacgat atttacaagc
    20161 aattaaagaa ttggagcaag agctatttac agtagcttaa tgaaaggaaa gtatgtcaat
    20221 tacatcattt gtaaaaagaa ttcaagatat cactcgaaac gatgctggtg ttaatggtga
    20281 tgctcaacgt attgagcaaa tgtcttggtt attattctta aaaatttatg atagccgtga
    20341 aatggtttgg gaattagaag aagacgagta tgagtcaatt atcccagagg aattaaaatg
    20401 gcgaaattgg gctcatgctc aaaatgggga acgggtattg acaggcgatg aattacttga
    20461 ttttgtcaat aacaagttat tcaaagagtt gaaagagctt gaaataactt caaatatgcc
    20521 tattcgaaaa acgattgtta aatcagcttt tgaagatgcg aacaactata tgaaaaatgg
    20581 cgtcttgtta cgccaagtca tcaatgttat tgatgaagtt gatttcaata gccctgaaga
    20641 tcgtcattcg tttaatgata tttacgaaaa aattcttaaa gatattcaaa atgctgggaa
    20701 ctcaggagaa ttttatacgc cacgtgcagc gactgatttt attgccgaag ttcttgaccc
    20761 aaaacttgga gaatcaatgg cagaccttgc ttgcggaaca ggaggcttct tgacttcgac
    20821 tctgaaccgt ttaagtagtc aacgtaaaac tagtgaagat accaaaaaat ataatacagc
    20881 tgtttttggt attgaaaaga aagcatttcc tcatctttta gcagttacaa atctgtttct
    20941 tcacgaaatt gatgacccta aaattgttca tggaaatact ttggagaaaa atgttcgtga
    21001 atatacggat gatgaaaaat ttgacattat tatgatgaat ccaccttttg gaggatcaga
    21061 attagaaaca ataaaaaata actttccagc agaattacgg agttctgaaa cagctgattt
    21121 atttatggct gtcattatgt atcgtttaaa agaaaatggt cgtgttggag ttattttacc
    21181 tgatggtttt ctatttggtg aaggtgtaaa aactcgcttg aaacaaaaac tggtagatga
    21241 gttcaacttg catacgatta ttaggttgcc tcatagtgtc tttgcaccgt atacaggaat
    21301 ccatacgaac attcttttct ttgataaaac aaagaaaaca gaagaaactt ggttttatcg
    21361 tttagatatg ccagatggtt ataaaaattt ctcgaaaact aagccgatga agtcagaaca
    21421 cttcaatcct gttcgtgact ggtgggaaaa tcgtgaagag attctggaag gtaagttcta
    21481 caaatctaaa tcatttacac ctagtgaatt ggctgagttg aattataatt tagaccagtg
    21541 tggctttcca aaagaggaag aggaaatctt aaatcccttt gagttgattc agaattatca
    21601 agcggaaaga gcaactttaa atcataagat tgataatgta ttagctgata ttttgcagtt
    21661 gttggaggac aaataatgac accagaacaa cttaaagcaa gtattctcca aagagcgatg
    21721 gaagggaaat tagtgccgca aaatcccaat gacgaacctg caagtgaatt attaaagaga
    21781 attaaagctg aaaaagaaaa acttatcagt gaaggaaaaa tcaaacgaga taaaaaggaa
    21841 actgagatat ttcgtggtga tgatgggaaa cattatggga agtttgctga tggaagcact
    21901 caagaaattg atgttcctta tgatattcct gatacttggg agtgggtgag gttttctaca
    21961 ttggttgaaa ttgtcagagg tggctctcca cgaccaatca aagattatct tacttctgaa
    22021 gtagatggaa taaattggat aaaaataggt gatactgaaa agggtgaaaa gtatataaat
    22081 aatgttaaag aaaaaatcaa aaaatcaggg cttaacaaaa ctagatttgt aaaaaaaggt
    22141 acatttttgt taactaattc tatgagtttt ggtagacctt atattttgaa tgttgatggt
    22201 gcaatacacg atggatggtt ggctatttcg aactatgaaa actcattaaa taaagattac
    22261 ctattctata ttctttcatc aaatgtagtt tattctcaat ttctatctct aattagtgga
    22321 gctgttgtga aaaacttgaa tagtgataaa gttgcttcta ttcttatccc tctccctccg
    22381 ctagctgaac aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa
    22441 tatgctgaaa gttataatag actagaacag ctagataaaa aatttccaga taaactaaaa
    22501 aaatctattc ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa
    22561 tcagtcgaag ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc
    22621 aagattaaaa agaaagattt ggacatttct attgtttccc aaggagatga taactcttat
    22681 tatgaggaag taccttgtga aataccagaa agttgggaat gggtgaggtt aaacgatata
    22741 acctcctaca ttcaaagagg gaagtctcca aaatattcaa atattcctat ataccctgtg
    22801 attgctcaga aatgtaatca atggtctggc ttttctattg acttagcaag atttattgat
    22861 cccgaaacag ttcatagtta ccagaaagaa agattactaa gagatggtga tttaatgtgg
    22921 aattcaacag gtctaggtac gttaggacga ttagctattt accatgaaaa taaaaatcct
    22981 tatggctggg ctgttgcaga tagccatgtt acagttataa gagtcttatc gggagttatt
    23041 aattgccatt tcatctataa ttttctttcc tctcctattg ttcagtcagt tattgaagaa
    23101 aaagcgtcgg gtagtacaaa acaaaaagaa ttattaacga aaactataaa agaatattta
    23161 atccccctcc caccccttcc tgaacaatcc agaatcgttg ataaaatcga acaatttttc
    23221 gcccatatta acgcactaat ttagtataat agttttacgt gcggtggaat ttctatcaaa
    23281 cataagatag gagttttacg ttgaaagatt ttgaattaca tttgaagaaa gctggtttag
    23341 ctgaaaatac tgtgcgttcg tacctttatg gtgttcgatt tttcttggag aattacgaac
    23401 tcaaaatgga agatttattt gaatacaaag gatatttatt agacaatttt aaacctaaaa
    23461 ctgtcaattt gcgactacaa ggagtaaata aatatctggc ttttattggt catgatgatt
    23521 tgaaattaaa atttgtcaaa gtacagcaaa aaccgttttt agaagatgtc attagccatg
    23581 ctgattacct ttttcttaaa cgtagtttga aaaaagatgg tattttaaaa tggcattttg
    23641 tcgtttggtt tttaggtgca actggggctc gtgtaagtga acttattaaa ctaaaagtag
    23701 agcatgtaga aatcggttat tttgacattt actcaaaagg tggtaaaatt cgtagactgt
    23761 acattcctaa aaaattaaga aatagttgtc ttagttggtt agaatcagaa aatcgccgaa
    23821 gtggttattt atttttgaat aaatttaacg aaccaattac agcaagagga gttgctcaac
    23881 agttaaaaaa ttatgctgat aaatacaaaa tgaatcctaa agtaatttac cctcattctt
    23941 ttaggcattt atttgctaag aattttttag cgaagtataa tgatattgcc ttgcttgcag
    24001 atttgatggg acacgaaagt atagaaacta ctcgaattta tctaaggaaa acagctactg
    24061 aacaacaaaa tattgtagat aaaattgtta attggtaaaa aataacaggt ggtcaaactg
    24121 actacctgct atttttgtga ttatg
//
LOCUS       DAVLIK010000031        23953 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLIK010000031 DAVLIK010000000
VERSION     DAVLIK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.031"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(105..2363)
                     /locus_tag="VXE87_001360"
     CDS             complement(105..2363)
                     /locus_tag="VXE87_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0842895.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKVLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
     gene            complement(2592..2822)
                     /locus_tag="VXE87_001361"
     CDS             complement(2592..2822)
                     /locus_tag="VXE87_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0842896.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3012..3695
                     /locus_tag="VXE87_001362"
     CDS             3012..3695
                     /locus_tag="VXE87_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0842897.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3695..4429
                     /locus_tag="VXE87_001363"
     CDS             3695..4429
                     /locus_tag="VXE87_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0842898.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4583..5440
                     /locus_tag="VXE87_001364"
     CDS             4583..5440
                     /locus_tag="VXE87_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0842899.1"
                     /translation="MTQIIDGKALAVKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5582..6454
                     /locus_tag="VXE87_001365"
     CDS             5582..6454
                     /locus_tag="VXE87_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0842900.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6736..7419
                     /gene="rpiA"
                     /locus_tag="VXE87_001366"
     CDS             6736..7419
                     /gene="rpiA"
                     /locus_tag="VXE87_001366"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0842901.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7433..8644
                     /locus_tag="VXE87_001367"
     CDS             7433..8644
                     /locus_tag="VXE87_001367"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0842902.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8646..9203
                     /locus_tag="VXE87_001368"
                     /pseudo
     CDS             8646..9203
                     /locus_tag="VXE87_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9203..10012
                     /locus_tag="VXE87_001369"
     CDS             9203..10012
                     /locus_tag="VXE87_001369"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0842903.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10723..11472
                     /locus_tag="VXE87_001370"
     CDS             10723..11472
                     /locus_tag="VXE87_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0842904.1"
                     /translation="MTGHFLGCYLAQIAAVEAYQKYPDFYNHVLRRVTTFSAPKVITS
                     RTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTPLIHNDRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATFDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            11495..12010
                     /locus_tag="VXE87_001371"
     CDS             11495..12010
                     /locus_tag="VXE87_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0842905.1"
                     /translation="MCQHKLRLTIKKARYVRIELEGYNALSLAEVEVFRFIATNGETA
                     IQVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNG
                     RNQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTT
                     LNSKVSDDDVL"
     gene            12664..13374
                     /gene="deoD"
                     /locus_tag="VXE87_001372"
     CDS             12664..13374
                     /gene="deoD"
                     /locus_tag="VXE87_001372"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0842906.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKFGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13397..13921)
                     /locus_tag="VXE87_001373"
     CDS             complement(13397..13921)
                     /locus_tag="VXE87_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0842907.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13974..14210)
                     /locus_tag="VXE87_001374"
     CDS             complement(13974..14210)
                     /locus_tag="VXE87_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0842908.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14278..15198)
                     /locus_tag="VXE87_001375"
     CDS             complement(14278..15198)
                     /locus_tag="VXE87_001375"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0842909.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15396..15800
                     /locus_tag="VXE87_001376"
     CDS             15396..15800
                     /locus_tag="VXE87_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842910.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFSIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16016..16597
                     /locus_tag="VXE87_001377"
     CDS             16016..16597
                     /locus_tag="VXE87_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0842911.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16594..17871
                     /locus_tag="VXE87_001378"
     CDS             16594..17871
                     /locus_tag="VXE87_001378"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0842912.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLEDGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17889..18551
                     /gene="deoC"
                     /locus_tag="VXE87_001379"
     CDS             17889..18551
                     /gene="deoC"
                     /locus_tag="VXE87_001379"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0842913.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18538..18927
                     /locus_tag="VXE87_001380"
     CDS             18538..18927
                     /locus_tag="VXE87_001380"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0842914.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19018..20070
                     /locus_tag="VXE87_001381"
     CDS             19018..20070
                     /locus_tag="VXE87_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0842915.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20214..21749
                     /locus_tag="VXE87_001382"
     CDS             20214..21749
                     /locus_tag="VXE87_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0842916.1"
                     /translation="MAHENVIEMRDITKVFGGFIANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIHRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21742..22800
                     /locus_tag="VXE87_001383"
     CDS             21742..22800
                     /locus_tag="VXE87_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842917.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22803..23759
                     /locus_tag="VXE87_001384"
     CDS             22803..23759
                     /locus_tag="VXE87_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0842918.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23844..>23953
                     /locus_tag="VXE87_001385"
     CDS             23844..>23953
                     /locus_tag="VXE87_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0842919.1"
                     /translation="MKLSYDDKVQIYELRKQGYSLEKLSNKFGINNSNLR"
BASE COUNT         6981 a         4303 c         5438 g         7231 t
ORIGIN      
        1 actatatatc ataatggaca aagggcaagc tgtcaagaaa ttacagttat tttagtaaaa
       61 aaagaagcag aaaaatttca ttttctactc cttttctata ggatttattt ttctttttca
      121 gaacttttaa cttcagtttt tttggcagat ttaatctgaa tgtttccctt gctagtcata
      181 actgctttga gaactttttc gcttggattt tcaaggtagt agtcagtgat tgtgtcctca
      241 atatagtctt gaatagttcg acgaagtggg cgtgctccca tttttggatc ataacctagg
      301 tcaaccaact tttccttgac cttgtcagtt acatccaaac gaatgttgtt gctagagagg
      361 cgcttgttaa catctgctag catgagctcg acaatctgaa ggaggttatc cttgctgaga
      421 gccttaaatt cgataatgcc atcaaaacgg ttcataaact ctgggctaaa gaagttaccg
      481 agttcaccga ggacagaatt ggtacgtcct tctctagcag caccaaatcc aacgctagct
      541 tcggtctttc ctgtacctgc atttgaggtc atgataatga tggcatcctt gaagctaacg
      601 gtgcgtcctt gcccgtctgt caaacgacca tcgtccaaga cttgaagaaa catgtgcata
      661 acatctgggt gagctttttc cacttcatcg agaaggatga gagaatatgg attgtggcga
      721 actttttcag ttaattgacc agcctcatca tagccaacat aacctggagg agcgccgacc
      781 aacttagcca cactatgttt ttccatgtat tcactcatat caaagcgaat catactatca
      841 gcagaaccaa aaagttcgat agccagttgt ttggaaagtt ctgtcttacc gacaccagtt
      901 ggcccaacga agaggaagct tccgattggg cggttagggg taccaagtcc gacacgatta
      961 cggcgaatag ccttggcaat cttatcgact gcatcatctt gaccaataac atgagacttg
     1021 agatcttcgg ctagatggat gagttgagat tgttctttct ctttcaaatc accaacaggg
     1081 atattggttt tctgctcgat aatgtgctca atagttttct cgctgatgat aggagtatcc
     1141 tggtctgtga tctttttctt ttgcatttcc ttatacttgg caatctggtc gcggaagtag
     1201 gccgccttct caaaatcttc ttctcgtgta gcttgagact tgagattttc agcctcaatc
     1261 aagcgctgat caattacttt aggatccaca aaattcaagg tcaagttcat cttagaacca
     1321 gcttcatcta ggaggtcaat ggccttgtca ggcaagaagc gatcttggat gtagcgattg
     1381 gaaagagttg cagctgcttc aatcgcagca tctgtatatt gaacgtggtg gtaatcttcg
     1441 tatttctttt gaatcccttt gagaatagtg attgtttcgt ccaccgttgg ttcatcgact
     1501 ttaacaggct gcatacgacg ctcgagggca gcatcctttt caatgatacg gtattcattg
     1561 agggtagtag caccgactag ttgcagttct ccacgagcaa gggctggctt gaggatattt
     1621 cctgcgtcca tattaccatc actcgcagaa ccagcaccaa caatttcatg gatttcatcg
     1681 ataaagagga tgatgtcttc acgtttgcga atttcttcca tgagtttttg catgcgttct
     1741 tcaaattgtc ctcgaatccc cgttccttga actaagctaa ccacatccag acggatgact
     1801 tgtttacctt ggagtttatg tggcacatcg ccatcgacaa ttttctgagc tagaccttcg
     1861 acaacggccg tttttccgac accaggttca ccgataagga caggattatt cttggttcta
     1921 cgattgagaa tctcgatgac acggataatc tcatcgtcgc gcccaataac ggggtcaatg
     1981 tctccacgac gggcaatttc agttacatta ataccaaatt cttccagcag gcctttttct
     2041 tggctaggtg gcggagtttg agcagatcca cgattttggg aaccataacc gccgtttcca
     2101 ccgtaacctc cacctgattg ggttggggga ataggaggag tattgctaga aggtctgaaa
     2161 ttgtttagat cattgaagaa atcaccaaag ggatcgaagt cacgattgtt cagatccgtc
     2221 atacctttga agaggctatt gttaggatct gttttgataa tcttatagca gttttgacag
     2281 aggtcaattt gtttttgttt tccattgaga ttggtgtaaa gatgaattgt tgagtcgtta
     2341 attttacagt tttgacaaag catacatcta cctcatttct ttctttagcc tgacttgttt
     2401 aaaggtcaaa aatagtcaaa ttctatactc tcattataac aggattgggg tgtaaagcaa
     2461 gtaaaaagat tgaagctttg agaagttgtt acaatgaaaa tttttgtgaa tttggactat
     2521 aaaaaaatcc tatttgtgag acaaaaagga ttttacttag acatgcaggg acaatcccag
     2581 cttgttttag attagtagag aagttcgtaa atttccattg cgattaagtc aatgctatca
     2641 aacgtatacg tttcgcgatc ttctacgtca cgaagggtaa agattgggcc gttttcttcg
     2701 tcgtggctgt acgcaacttc tgcaacaaca actccttcgc gttcaaaatt acgttttaaa
     2761 tttccgccat cgtttgccat tgcttcaagg cggttgatga ttctaaccaa atgtgattcc
     2821 attttgattc tccttcattt cttatcgtta ctattttacc ataaaggagg ccaacttgac
     2881 tagaaaaaac taagatttct cactaattct gctagtttaa agatttttaa ataaattgga
     2941 taaaagattt aaattttaat tcaaaacatg ttataatcat acagtattct attttagaaa
     3001 gcagtgtgac tatgaatttt tcttttttac ctaagtattt accttatttt aactatgggg
     3061 ctgttgtgac gattcttatt tctatctgtg ttatcttttt gggaactatt ttgggtgttg
     3121 tcttggcttt tgggcaacgt tcaaagttta aaccgcttgt ttggttggcc aacttgtacg
     3181 tttggatttt ccgtgggaca ccgatgatgg ttcaaattat gattgccttt gctcttatgc
     3241 atatcaatgc tccgactatt cagattggaa ttttaggtgt tgatttttcg cgtctgattc
     3301 cagggatttt gattatctct atgaatagtg gtgcttatgt ttcggagact gttcgtgccg
     3361 gaatcaatgc ggttccaaaa ggtcagctag aggcggctta ttcgctaggg attcgtccta
     3421 aaaatgcgat gcgttatgtg attttgccac aagcaatcaa aaatatcttg ccagcattgg
     3481 ggaacgaatt tatcaccatt atcaaggaca gctccctctt atcagctatt ggggtcatgg
     3541 agttgtggaa tggggctaca acagtttcta caacaaccta tctaccttta acaccacttt
     3601 tatttgcagc attttactac ttgattatga cctctattct gacagtagcc ttgaaagctt
     3661 ttgaaaaaca tatgggacaa ggagataaga aataatgaca gaaaccttga taaaaattga
     3721 aaatttacat aaatcttttg gaaagaatga agtattgaag ggaatcaacc tcgagattaa
     3781 aagaggagaa gttgtcgtta tcatcggtcc ttcagggagt gggaaatcta ccttgcttcg
     3841 ctctatgaat ttgttggagg aagcaaccaa ggggaagctt atctttgagg gagtcgatat
     3901 tacggacaag aagaatgact tgtttgccat gcgtgagaag atgggcatgg ttttccaaca
     3961 atttaacctc tttcctaata tgactgtgat ggaaaatatt accttgtcac ctatcaagac
     4021 taaaggtgaa agcagggaag ttgctgagaa gagagcccaa gagcttttgg aaaaagttgg
     4081 tttgccagat aaggcagacg cttatccaca gagtctgtcg ggtgggcaac aacaacggat
     4141 tgccatcgcg cgtgggttgg ctatggaacc agatgttttg ctctttgacg aaccaacttc
     4201 agccttggat cctgaaatgg taggtgaggt attggctgtt atgcaagacc ttgccaagtc
     4261 agggatgact atggttatcg taacacatga gatgggattt gcccgtgagg tggcagatcg
     4321 tgttatcttt atggcagacg gtgtggttgt tgaagatggg acacctgagc agatttttga
     4381 acaaacccaa gaacaacgga ctaaagattt cttgagtaag gttttataat ctattttaaa
     4441 atttcaagac aagattagtg aaaagttcaa ccagagcttt ttcttatagt ttgaaactat
     4501 aggataacct aggaaagaag tgttagaggg cactagcagt ttttggtata atggaagata
     4561 tttgaaagaa aagagaagtg atatgacaca gattattgat gggaaagctt tagcggtcaa
     4621 attgcagggg cagttggctg aaaagactgc aaaattaaag gaagaaacag ctctagtgcc
     4681 tggtttggta gtgattttgg ttggggataa tccagccagc caagtctacg ttcgcaacaa
     4741 ggagaggtca gctcttgcgg ctggttcccg tagcgaagta gtgcgagttc cagagaccat
     4801 tactcaagag gaattgttag acctgattgc taaatataat caggatccag cttggcatgg
     4861 gattttggtc cagttgccat taccaaaaca tatcgatgaa gaggcggttt tattagccat
     4921 tgacccagaa aaggatgtgg atggtttcca tcccttaaac atgggacgtc tttggtctgg
     4981 acatccagtc atgattccct cgacacctgc aggaattatg gaaatgtttc atgaatatgg
     5041 gattgacttg gaaggtaaaa atgcggtcgt catcggtcgt tcaaatatcg ttggaaaacc
     5101 tatggctcag cttcttttgg ctaaaaatgc gacagtaacc ttgacccact cacgaactca
     5161 taatcttgcc aaggtggctg ctaaagcaga tattcttgta gtcgcaatcg gccgcgccaa
     5221 gtttgtgact gctgactttg tcaaaccagg tgcggttgtc attgacgttg ggatgaaccg
     5281 agatgaaaat gggaagctct gtggagatgt tgattatgag gcagttgcac cacttgctag
     5341 ctatatcacg ccagtccctg gaggtgtcgg tcctatgacc attaccatgc tgatggagca
     5401 aacttatcaa gcagcacttc ggacattgga tagaaaataa gagaaacatt cgattaatag
     5461 agtgtatttt ctatagctat atctaaaatg gcagaaatga atattaaatt ttagatataa
     5521 gattacaaaa ggaggtctgc gtctcctttt tattgtataa taaaagtgag aggaaaaaag
     5581 gatgaaagtg attaatcaaa ccttattaga aaaagttatt attgaacgtt ctcgttcaag
     5641 tcataaagga gattatggtc gtctgctgct gcttggtggt acttatcctt atggaggtgc
     5701 catcatcatg gctgctttag cagctgtaaa aagcggtgca ggattggtga ccgttggaac
     5761 ggacagggaa aatatcccgg ctctgcacag ccatttacct gagcctatgg ccttttctct
     5821 tcaagaccag caattgttaa aagagcaatt ggagaaggca gaagttgtct tgttggggcc
     5881 tggtttacga gacgatgctt ctggagaaaa tctagtaaaa caggtctttg ttaatttaag
     5941 ccaaaatcag attttgattg tagacggagg tgccttgacc attcttgcta ggacaagttt
     6001 gtcatttccc tcaagccagc ttatcctaac tcctcaccaa aaagaatggg aaaaattatc
     6061 tggaattacg attgaaaagc aaaaggaaga tgcaacggct agtgttctga cttccttccc
     6121 tcaaggaaca attttggtgg agaaaggccc agctactcgt atttgggaag ttggccaatc
     6181 tgattattac cagttacagg ttggtggtcc ttatcaggcg actgggggaa tgggagatac
     6241 tctggctggg atgatcgcag gatttgtagg ccaattccga caggccagtc tctacgagcg
     6301 tgtggcagta gcgacccatc ttcattcagc catagcccaa gaactatctc aagaaaatta
     6361 tgtggtctta ccgacggaaa tcagcaggta tcttcccaaa ataatgaaaa ttatttgtca
     6421 acaagagagg gtaagcaaag ataaacttgt ttaaaataga cagataaatc tacttccttc
     6481 tcttaattta tgattcttga aatgcgcctg ctttaaggct aaactagacg tatcaaagtt
     6541 aagagtttgt ttttgtaact ggaaagagat gaacaaatca aatacataaa agataaactc
     6601 atttttattc gtttggtaaa aataaaatgc atatttttaa agaaagattg atgaaaaatg
     6661 tagatttgat gtttttactt gaataaaaag cggtttcata gtaaaataag aactgagaat
     6721 gatggaggta aatcggtgga aaatctgaag aaaatggcag gtatcaaggc tgctgagttc
     6781 gtgagcgatg gaatggtcgt tggacttgga acaggctcga ctgcctatta ttttgtcgaa
     6841 gaaatcggtc gtcgtatcaa ggaagaagga ttgcagatta cagctgtaac aacttctagt
     6901 gtgaccacta aacaggcaga aggccttaat atcccgctca agtctattga ccaagtagac
     6961 tttgtcgatg tgacggttga tggcgcggat gaagtggata gtcagtttaa tggaatcaaa
     7021 ggcggtggtg gtgcccttct catggaaaag gtggtcgcaa caccatcaaa agaatacatt
     7081 tgggtggtgg atgaaagcaa gctggtcgaa aaactaggtg cttttaaatt gccagtagaa
     7141 gtggttcagt atggtgcaga gcaggtcttt cgtcattttg aacgagctgg ctacaaacca
     7201 agtttccgtg aaaaagacgg ccaacgtttt gtgacggata tgcagaattt tatcattgac
     7261 ctcgccttgg atgtcattga aaatccaatt gcttttggac aagaattgga ccatgtcgtt
     7321 ggtgttgtgg agcatggttt attcaaccaa atggtggata aggtaatcgt tgctggacga
     7381 gatggagttc agatttcaac ttcaaaaaaa ggaaaataga agggggcata agatgtctaa
     7441 atttaatcgt attcatttgg tggtactgga ttctgtagga atcggtgcag caccagatgc
     7501 taataacttt gtcaatgcag gggttccaga tggagcttct gacacactgg gacacatttc
     7561 aaaaacagtt ggtttgaatg tcccaaacat ggctaaaata ggtcttggaa atattcctcg
     7621 tgaaactcct cttaagactg tagcagctga aatcaatcca actggatatg caacaaaatt
     7681 agaggaagta tctcttggta aggatactat gactggacac tgggaaatca tgggactcaa
     7741 cattactgag cctttcgata ctttctggaa cggattccca gaagaaatcc tgacaaaaat
     7801 cgaagaattc tcaggacgca aggttattcg tgaagccaac aaaccttatt caggaacggc
     7861 tgttatcgat gattttggac cacgtcagat ggaaactgga gagttgatta tctatacttc
     7921 agctgaccct gttttgcaga ttgctgccca cgaagacatt attcctttgg atgaattgta
     7981 ccgtatctgt gaatacgctc gttcgattac ccttgagcgt cctgcccttc ttggtcgcat
     8041 cattgctcgc ccttatgtag gtgaaccagg taacttcact cgtacggcaa accgtcgtga
     8101 cttggctgta tctccatttt ccccaactgt tttggataaa ttgaatgagg ctggtatcga
     8161 tacttatgct gtgggtaaaa tcaacgatat ctttaacggt gctggtatca accatgacat
     8221 gggtcacaac aagtcaaata gtcatggaat tgatacacta ttgaagacta tgggacttgc
     8281 tgagtttgaa aaaggattct cattcacaaa cctagttgac tttgatgccc tttacggcca
     8341 tcgtcgtaat gctcacggtt accgtgattg tttgcatgag tttgatgaac gcttacctga
     8401 aattatcgca gctatgagag agaatgacct tctcttgatt actgcggacc atggaaatga
     8461 cccaacgtat gcagggacgg atcacactcg ggaatatatt ccattgttgg catatagccc
     8521 tgcctttaaa ggaaatggtc tcattccagt aggacatttt gcagatattt cagcgactgt
     8581 tgccgataac tttggtgtgg aaactgctat gattggggaa agtttcttag ataaattggt
     8641 ataagatgac gcgctatgct ttgctggtga gaggtatcaa tgttggtagt aagaataagg
     8701 tcgttatggc ggagcttcgt caagaattga caaacttggg actggaaaag gttgagagct
     8761 acatcaacag tggcaatatt ttctttactt cgatagattc caaagcccaa ttggtttaaa
     8821 agctagagac tttctttgca gtccattatc catttattca gagcttttct ttactgagtc
     8881 tagaggactt tgaggcggaa cttgaaaatc taccagcttg gtggagcaga gacttggcac
     8941 gaaaagattt tctcttttac actgagggtt tggatgtgga ccaagtcatc gcgacagttg
     9001 aaagtttaga gctgaaagat gaagtgcttt attttagaaa acttgggatt ttctggggga
     9061 aattttctga agaatcctat tctaagactg cctatcataa gtacttgctg aaggtgcctt
     9121 tctaccgcca cattactatt cgtaatgcta aaacctttga caaaattggt caaatgctaa
     9181 aaaataataa aggagacaca taatgacatt tttaaacaaa atccatgaaa ctgctacttt
     9241 cctgaaagaa aagggaattg cagcccctga gttcggtcta atccttgggt caggacttgg
     9301 agaattggca gaagaaatcg aaaatccagt tgtagtagac tatgctgaga ttccaaactg
     9361 gggccgttca acagtagtcg gtcatgctgg taaattggta tatggtgaac tggcaggtcg
     9421 caaggtcttg gctcttcaag gtcgtttcca tttctatgaa gggaatcctc tggaagtggt
     9481 gactttccca gttcgtgtga tgaaagttct tggatgtgaa ggtgttattg taaccaatgc
     9541 agctggcggt atcggatttg gtcctggtac cttgatggct atctcagacc atatcaacat
     9601 gacggggcaa aatccattga tgggtgaaaa cttggatgac tttggcccac gtttcccaga
     9661 tatgtctagg gcctacacac cagaataccg tgccactgcc catgaagtgg ctaaaaaact
     9721 taatatcaag cttgatgaag gtgtctatat cggagttact ggtccgactt atgaaacacc
     9781 agcagaaatt cgttcctata agacactggg agcagatgca gttggtatgt ctacggttcc
     9841 tgaagttatc gtggcagccc actctggctt gaaagttcta ggaatttcat gtatcactaa
     9901 ctttgcggct ggtttccaag aagaactcaa tcacgaagaa gttgtagaag tgactgaacg
     9961 tgttaaaggt gatttcaaag gcttgcttaa agcgattctt gctgaattgt aagaaaaaag
    10021 atttaaaagg ggaagtacct ctgttttttc aggattgact gcctatccgg attaaagaag
    10081 aaacagagga atactatgag cttcttcctg ctcttataac tgaaagaagc ggaagaatag
    10141 gtatgtctga tctgatagcc agcattgtga aagacaagat tctaggatac tagcattagc
    10201 ttcctagcca agcagactag tatgataagg agagatgaga atgaattgac tttctgaatt
    10261 tctcagtctt atcatatata gcacaatgag atttcgcttg agtctgcttg taaataaacg
    10321 aaaagaaaga taagaaataa tgaaaattgg tcaacgaatt atgcgctttg gcataaaaaa
    10381 ttaagtatcg gagttgtatc tgttgtagtc ggctttgatt tctagctcca gctggaattt
    10441 cagccaatga agtaaagtaa gatgtaacat ctgaagtggt aataggtgtg ttagattcta
    10501 aggaggaatt gaaagagtca gaaaatgatg ctctaaaact agaaactcct cttagagagg
    10561 agccaagact agctcctcaa acgcttccgg aagcaagtga agttagttct tgaaaacaaa
    10621 agggaagagt caaaagtaga gataacagaa ccagctcaag cggatgatat ccgcaaggtt
    10681 gttggggaat tagccaagga tataagtatt actaagttgt atatgacagg tcattttctt
    10741 ggatgttacc tagctcagat tgcagcggtt gaagcttacc aaaaatatcc tgatttttat
    10801 aaccatgtat tgaggagagt gacaactttc agtgctccta aagtgattac ttccagaact
    10861 gtttggaatg ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt
    10921 agtggaaaaa ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat
    10981 aatgatcgtg atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc
    11041 tattttgaaa gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttt
    11101 gataaacatg gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct
    11161 ctacctcaat cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa
    11221 caggttactc aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa
    11281 gtcgatggta actatggtca caattctgtc actcatacaa acttccaatc taagccttgg
    11341 tggcaagtag atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca
    11401 gacactgccc aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa
    11461 gaaattgagt gaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac
    11521 cataaaaaaa gcgcgctatg ttcggattga gctagaaggc tataatgccc tcagtcttgc
    11581 agaagttgaa gttttccgct ttatagctac gaatggtgaa acggcgatac aagtttctaa
    11641 gtcagttcaa ccaatcagtc agactcctgt gaaagataaa acattgacaa ttcaacacag
    11701 tggagcttac attgcccgct actccataac ttgggaagaa gttacagtag ataaagatgg
    11761 aaaccaagtt gttcgtagtc attcttggga aggaaacggt cgcaaccaga ctgcaggttt
    11821 tgtcctcaac ctcccaatca aagaaaatat gagaaatctg cgagttaaga ttgagaaaaa
    11881 gacgggccta ctatggaata gatggcaaac aatctatgaa aacagaccaa ttttagctca
    11941 accccaccgt aaaattaccc attggggtac gacattgaat tccaaggtga gtgacgatga
    12001 tgtcttgtaa tctgatggta gaatgacagt tagtttgtct agtttataag aaagtactac
    12061 ctgagcttga atagaactca ggtagctctc tatgaaagaa caaaattaat actcaatgaa
    12121 aatcaaagag caaactagga aactagccgc aggttgctca aagcactact ttgaggttgt
    12181 agataagact gacgaagtca gtcacatata taatccaagg cgacgttgac gtggtttgaa
    12241 gagattttag aagagtataa acagaaaggt agagcgcgtg ttctaatttg aacacgagta
    12301 gaaaactttt ctaaaaacaa aaacgaaagg atgggtaaac tgtattcgct gaactgaata
    12361 cgggcgactc tcctctaaat caaaattaag aaaggaattg accccaccct aaaagtagtg
    12421 ggaaaaagat agttggtcta gcgagcatcg ctcactgcgc ccaactccta ttttcccttc
    12481 gctttttgat gggtttggta tctttctcaa tataaaatat aaaataaaga aaggtagagc
    12541 gcgtgttcta atttgaacac gagcggaaaa ctcggaaaat agataatctg actgaaaaat
    12601 caggatttct cgtcaggttc ctaattttca gtcgttttct tctcgctctt tgtatcataa
    12661 attatgtcta tccatattgc tgctcagcag ggtgaaattg ctgataaaat tcttcttcct
    12721 ggggatcctc ttcgtgctaa gtttattgcg gagaatttcc ttgatgatgc tgtttgtttt
    12781 aacgaagtgc gtaacatgtt tggttacact ggtacttaca agggtcactg tgtatctgtc
    12841 atgggaactg ggatgggaat gccatctatt tcgatttatg cgcgtgagtt aatcgtagac
    12901 tacggtgtga agaaattgat tcgtgtggga actgcaggtt ctttgaatga agaggttcat
    12961 gttcgtgaat tagttttggc gcaggcggct gcaaccaact caaacatcgt tcgtaatgac
    13021 tggccacagt acgattttcc acaaattgct agctttgatt tgcttgataa agcctaccat
    13081 atcgccaaaa aatttggtat gactactcac gttgggaacg ttttgtcatc tgatgtcttt
    13141 tactcaaatt actttgaaaa gaatatcgag cttggtaaat ggggagtcaa ggctgtggaa
    13201 atggaagcag cagctcttta ctatcttgct gcccaatacc atgttgatgc gctagctatc
    13261 atgaccatct ctgatagctt ggtcaatcca gacgaagaca caactgcaga agaacgtcaa
    13321 aataccttca ctgatatgat gaaggttggt ttggaaacct tgattgcaga ataattatag
    13381 ccaaaaagga agccctttat gaattgtagg acttcctttt cttatccaga aattgatcta
    13441 gttctctctg atttcgaaga atagtgactt tatgtgaata ttcttggcaa agtttttggt
    13501 aattttcttt ttgagttttg ctacgcccat cccaaagaat ccatctgata aactcccact
    13561 caaagcgttc agggcaatct gccgccatac tttctctgac ttttccacgg tatttaagat
    13621 aacgcttaaa ggctctaaag agacaggtca atggcaaaaa attgagaaag atgatttggt
    13681 cagcttcttg cattcgttct tggtagtagc accaagaata attaccatcg atgacccaag
    13741 ctttatgctt ggtgagaaag ttttttatct cggttaacat ccattcgcag tcactgtctt
    13801 gccaaccagg ttgaaattgg agtgtgtcca tgtgcagttt tggaatggag tagtagttag
    13861 ataacttttc tgctagagtt gacttaccag aaccagaata tccgataatt gtgattttca
    13921 ttttctacct tttcctattt ggagacaaaa aaacagcctc tatggactgt ttcttattta
    13981 gcaagtttag ctgaaagacg agctttatcg cggcttgctt tgtttttgtg aatcaaacct
    14041 ttagtttctg ctttatcgat agctgagcta gcagcacgga aaagttcttc agatgggttt
    14101 gcttcaaaag cttttatagc agtacgcata gctgattttt gagctgagtt cttttcgttt
    14161 tgtttaacgt tcaattcagc gcgtttgata gctgatttaa tgtttgccaa tgttcttacc
    14221 tccatattta ctaactatac cattatatat gaaaacttac gttttgacaa gggaaaatta
    14281 tttttttaag taaatttcat cgatttcatg gttcttgctt ttatgaagaa tcacttctgc
    14341 acgatttctg gttggttcaa tataattttg tagatttgtg agattgatac tggtccagac
    14401 ctgatgggca aaggcttcca cttccccaat cggcatctga gtaaaacgat aatagtagct
    14461 atcagggtcg ttttgggcta gactcagcat tttcaagaaa cggtccagat accaactttc
    14521 aatatcatcc actccagcat ctacatagat ggaaaagtca aagaagtcag tgatatagag
    14581 acgatcgttt tgtggatttt gaaagacatt gattccctca acaattacaa aatcagcagc
    14641 tttgacactt tgtttctctt cgggtacgat gtcgtaaact tcatgagaat agacaggaat
    14701 atctacatct tgtccatttt tgatgcggtc caagaagttg agaagagctt ccatatcata
    14761 gctttcagga aatcctttac gatttaaaat cccctgctca atcaaggttt gattgggata
    14821 gagaaaacca tcagttgtaa ccaactcaac cgtagcatct gtaaacgtac gggacagtag
    14881 gatttgaagt aggcgactgg ttgtggattt tccaacggca acactcccag aaaccccaat
    14941 aataaaaggt tgagatttac tttcacgttg gaggaaaatt ccttttgaaa aggctaaatc
    15001 ttccttagtt cgcttgtaaa tctgaatcag atgagccaag gggagataga tatctgtaac
    15061 gtcttggaga ctgatttggt cattaaaact cttgatagat tccaattctt cttctgtcaa
    15121 aggaggtgtt gtctttcgat gtaaagattg ccaagtctgg cggctgattt tttcaaaatg
    15181 taaaaattcg ttggtcattt gttttcccct agatattttg tctatcatac cataaaaatc
    15241 taaaaaaata aagcggtttc ttgaatgtgg taagtcaatg gtatatagta taagtgatca
    15301 atttattgat gaaataggag atagattcta ctgatttata agtttataag cttataaagg
    15361 gggcttttta gttcacaact tataggaggt gtactatgaa aatcttaaaa cgttacatat
    15421 tggaactctg ttttatttta agttttgctt taccttttat aaaaggagcc aatgcagata
    15481 atggtatatg ctttgtggaa acctattacg gttttacttt tttgatggaa catgctattg
    15541 taacagctgt ctttatctat tcgttttcaa ttgctttctt actaaaaaaa cgatgggcga
    15601 aatggattgc tgctggtagt tattgctttt tagtcctatg gattgcgaca gagggttatt
    15661 tcttccgcat gtcactagaa gatttgatac gactttggac aagtttggaa atcctgacac
    15721 aaacgtatca gttgggcttt tatctaaaca ttttgttggg aattttgttg ataataaagt
    15781 attttaaggt taagcaatag aaataataat ctgcctgatt atagatgata aactttttgt
    15841 ttttatctgg actgtgatat ttatagttct aaatggttta ttatttataa gtgttgaaag
    15901 agattgaaga aaatggcttc gtgactcgct ttcttcggtc tttttcgttt tattatcaat
    15961 ttgtaaacga tttacaattt gagtcaaatt atggtaaaat agtgtcatga gtaaaatgta
    16021 ttatgcagag aatcctgacg ctgctcacga cattcatgag ttgagagtag agttgttggg
    16081 acaaaaaatg acctttttaa cggatgcggg tgtttttagc aagaaaatag ttgactttgg
    16141 aagtcaacta ttgctcaagt gtcttgaggt caaccaagga gaaactgtcc ttgatgtagg
    16201 ctgtggttac ggacctttgg gtttgtcctt agctaaggct tatggagttc aggctactat
    16261 ggttgatatc aacactcgtg ccttagattt agctcggaga aatgctgaaa aaaataatgc
    16321 aaaagcgacg attttccagt ccaacatcta tgaacaagtt gaaggacatt ttgatcatgt
    16381 catttccaat cctcctatcc gtgcgggcaa gcaagtcgtt catgaaatca ttgagaaaag
    16441 taaagatttc ttggaaactg gtggggattt gacaatcgtc atccagaaaa aacaaggggc
    16501 tccaagtgct aagtccaaga tggaggatgt gtttggtaat tgtgaaatcc ttaaaaaaga
    16561 caaaggatac tatatcctta gaagtgtgaa agaatgagag cagttgattt aatacaaaaa
    16621 aaacgagacg gtcaagaact gacttcaagt gaaattgaat ggctggtaga aggctatgtg
    16681 tcaggaactg ttcctgatta tcagatgtct gcctttgcta tggctgttta ttttaaagga
    16741 atgacgactc gtgaaatttc tgatttaacg atgaatatgg ttaagactgg gcaagagttt
    16801 gacctgtcag ccattgatgg tgtgaaagtt gacaagcatt ctactggtgg tgtcggcgat
    16861 aaggtaacct tgattttagc tcctcttgtt gctagcttcg gtgtgcctgt agcaaaaatg
    16921 agtggtcgtg gtcttggcca tacaggcgga acaattgata aattggagtc cattaggggc
    16981 tatcaagtag aacgtagtca agaggatttt attcgtcagg ttcaggatat tggagtatct
    17041 gtcattgggc aatcagacca gctggtcaaa gcagataagc ttctctatgc ccttcgtgat
    17101 gtgaccgcaa ctgtcgacac gattcctttg attgcgagtt cggtgatgag caagaaaatc
    17161 gcggcagggg cggatgctat tttgctagac gtgactgtcg gtgagggtgc cttcatgaag
    17221 acggttgatg aggcgcgtga gttggctcaa actatggtag atcttggtaa ggttgttgga
    17281 cggaagacag tagcagtgat tacggatatg agccagcctt tgggacgagc gattggaaat
    17341 cgtctggaaa tccttgaagc attggagatt ttgcaaggtc aaggacgtca ggatattacc
    17401 cactttattt gtgaattggc tcaaattatg cttggcttgg caaatgttaa caagactgtt
    17461 gaagaagttc gccaacatct tgaggatggt caagcactgg ctaagtttga ggaaatggtg
    17521 caagcccaag gtggagactt ggaagacctc tatcgtcctg taaatgtagc tcatgtggtg
    17581 gaaatccctg ctcaggaaac aggtgtcatt tcagctcttc cagctatgga ctttggtctt
    17641 tatgccatga ggctgggtgc tggtcgtgca gttaagtctg atgccttgga ctatgaaaca
    17701 ggaattgttt ttgaaaagaa gattggagac tccgttcaaa agggtgaaat tgttgcaaaa
    17761 gtatacacaa atgaaaaaat tccacctcaa ctagttacag atttccaaaa atgtgttaaa
    17821 ataagtgatg aagtgaaaaa aatccgtgaa attgtagaaa tcatctccta aatggaggga
    17881 aaaccgaaat gaaattaaat aaatatatag atcatacgct tttaaaacaa gatgcaaaga
    17941 aaaaacaaat tgatagtttg ttgtctgagg ctagagagta tggctttgcc agtgtttgcg
    18001 ttaatccaac ctgggttgaa catgctaaaa aagggcttga aggcacagat gttaaggttt
    18061 gcacggtagt aggtttccct ttgggagcaa caacttcagc cgtgaaagca tttgagacaa
    18121 aagaagctat ccaaaatggt gcagatgaga ttgatatggt gatcaatgtt ggagctctca
    18181 aatcaggtaa tttagccttg gttgagtcag atattcgcgc agtagtggaa gcaagtggtg
    18241 ataagttagt gaaagtcatt attgaagctt gccttctgac agaccaagaa aaagttgttg
    18301 tttgccaatt ggcccaaaaa gctggggctg actttgtcaa aacatctact ggcttttcaa
    18361 ctggtggtgc tacgatagca gatgttacat taatgcgtga aacagttgga tctgatatgg
    18421 gagtcaaggc tgctggtgga gctcgttctt atgcagatgc tcttgccttt gtcgaagcag
    18481 gtgcgacccg tatcggaacg tcagctgggg tagctatttt aaaaggagaa ttggcagatg
    18541 gcgactactg agttgattga actggcaatt gaaaccagca aacatgccta tgtcccctat
    18601 tctcactttc ctatcggagc agttttagta gccaaagacg gaaatgttta cacgggagtg
    18661 aatatcgaaa atgctagcta tcctttgacc aattgcggtg agagaacagc tatttttaag
    18721 gctatatctg aaggccaaag agaattttca gaattgattg tctatggtca aactgaaaaa
    18781 ccgatttcac catgtggtgc ttgtcgccaa gtaatggtcg aattttttga acaagattta
    18841 aaagtgacct tagtcgcaaa agataaatcg acggtcgaga tgacggtcgg ggagttactt
    18901 ccatattctt ttacagactt aaattagtct gagtcgctct ttgagtggca agggtctttg
    18961 tgaccaatca atccatactt gcaacatcgt tgcacatctt atttaggagg ttcagtaatg
    19021 aacaagaaac aatggctagg tcttggccta gttgcagtgg cagcagttgg acttgctgca
    19081 tgtggtaacc gctcttctcg taacgcagct tcatcttctg atgtgaagac aaaagcagca
    19141 atcgtcactg atactggtgg tgttgatgac aaatcattca accaatcagc ttgggaaggt
    19201 ttgcaggctt ggggtaaaga acacaatctt tcaaaagata acggtttcac ttacttccaa
    19261 tcaacaagtg aagctgacta cgctaacaac ttgcaacaag cggctggaag ttacaaccta
    19321 atctttggtg ttggttttgc ccttcacaat gcagttgaag aagcagctaa agaacacact
    19381 gacttgaact atgtcttgat tgatgatgtg attaaagacc aaaagaatgt tgcgagcgta
    19441 actttcgctg ataatgagtc aggttacctt gcaggtgtgg ctgcagcaaa aacaactaag
    19501 acaaaacaag ttggttttgt aggtggtatc gaatctgaag ttatctctcg ttttgaagca
    19561 ggattcaagg ctggtgttgc gtcagtagac ccatctatca aagtccaagt tgactacgct
    19621 ggttcatttg gtgatgcggc taaaggtaaa acaattgcag ccgcacaata cgcagccggt
    19681 gcagatattg tttaccaagt agctggtggt acaggtgcag gtgtctttgc agaggcaaaa
    19741 tctctcaacg aaagccgtcc tgaaaatgaa aaagtttggg ttatcggtgt tgaccgtgac
    19801 caagaagcag aaggtaaata cacttctaaa gatggcaaag aatcaaactt tgttcttgta
    19861 tctactttga aacaagttgg tacaactgta aaagatattt ctaacaaggc agaaaaagga
    19921 gaattccctg gcggtcaagt gatcgtttac tcattgaagg ataaaggggt tgacttggca
    19981 gtaacaaacc tttcagaaga aggtaaaaaa gctgtcgaag atgcaaaagc taaaatcctt
    20041 gatggaagcg taaaagttcc tgaaaaataa tggatggaag tcatttctta ggaagcggcc
    20101 aagggccgct tttttaagag ttgagacaaa gtcattttgt ctcagtaaag cttgctacta
    20161 gacaaactag caagttttat tgaaataaaa taagactctg aaaggaagag cacatggcac
    20221 acgaaaatgt cattgagatg cgtgatatta ccaaggtgtt tggtggattt attgccaacg
    20281 acaaaatcaa cttgcaccta cgaaaaggtg aaattcatgc acttttagga gaaaatgggg
    20341 ctggtaagtc cacgctaatg aacatgttag caggccttct tgaaccaact agtggtgaaa
    20401 tcgcggtcaa cggtcaagtt gtcaatctcg actccccatc taaagcagct agcttgggaa
    20461 tcgggatggt tcaccagcac tttatgttgg ttgaagcctt cacagtggct gaaaacatca
    20521 ttttaggtag tgaattgact aaaaatggtg tgctagatat cgctggagct agcaaagaaa
    20581 tcaaggctct ttctgaacgt tatggcttag ctgttgaccc ttctgccaag gtagcagata
    20641 tctcagttgg agcccaacaa cgtgtagaaa ttttaaaaac actttatagg ggggctgata
    20701 tccttatctt tgacgaacca acggctgttt tgactccatc agaaattgat gagttgatgg
    20761 ctattatgaa aaatcttgtc aaagaaggaa aatcaattat cttgattacc cacaaattgg
    20821 atgaaattcg cgcagtttct gaccgtgtta cagttatcca tcgtgggaaa tcaattgaaa
    20881 ccgttgaaat tgcaggggct accaatgctg atttggcgga aatgatggta ggacgttctg
    20941 tttcctttaa aacagagaag caagcctcta aaccaaaaga agtggttttg tctatcaaag
    21001 atttggtggt caatgaaaac cgtggtgttc cagctgttaa aaatctgtcc ttggatgttc
    21061 gtgctggaga gattgttggt attgcgggga ttgatggaaa tggtcagtct gaactgattc
    21121 aagccattac aggtcttcgt aaggttgaat ctggtagcat tgagctaaaa ggagattcaa
    21181 ttgtaggctt gcacccacgt cagattacag aactaagtgt tgggcacgtt ccagaagacc
    21241 gtcaccgtga tggcttgatt ttggaaatga tgatatctga aaatattgcc cttcaaacct
    21301 actataaaga accacatagt aaaaatggaa ttttgaacta ttcaaatatt acttcttatg
    21361 ctaaaaagct gatggaagag tttgatgttc gcgctgccag tgaattagtt cctgcagctg
    21421 cactctcagg aggaaatcaa caaaaagcaa ttattgctcg tgaaattgat cgagatcctg
    21481 atctccttat cgttagccag ccaactcgtg ggttggatgt cggtgccatt gagtatatcc
    21541 acaaacgctt gattgaagag cgtgataatg gcaaggctgt ccttgttgtc agctttgaat
    21601 tggatgagat tttaaacgtc tcagaccgta ttgccgttat ccacgatggt aagattcaag
    21661 gtattgtatc accagaaaca accaataaac aagaacttgg tgtcttgatg gctggtggaa
    21721 acttgggaaa ggagaagagt gatgtctaaa aaattacaac aaatttcggt tcccttgatt
    21781 tctgtatttc taggaatttt actcggagcc attgtcatgt ggatcttcgg ttatgatgct
    21841 atttggggct acgaagaatt attctataca gcctttggca gtctgcgtgg gattggagaa
    21901 atcttccgtg ctatgggtcc tctggtcttg attggtcttg gttttgcggt tgccagtcga
    21961 gctggtttct ttaacgtcgg acttcctggt caggctttgg caggttggat tctcagtggt
    22021 tggtttgcgc tgtcgcatcc agatatgccc cgtcccttga tgattctagc aaccatcgtg
    22081 attgccttga ttgctggtgg gattgtcgga gcgattccag gtattcttag ggcctatcta
    22141 gggacgtcag aggttattgt aaccatcatg atgaactaca ttgtcttgta tgtagggaat
    22201 gcctttatcc atgctttccc taaagacttc atgcaaagta cagattcgac cattcgtgtt
    22261 ggggctaatg caacctatca gacaccttgg ttggctgagt tgactggtaa ctcacggatg
    22321 aatattggta ttttctttgc catcattgcc gttgcagtta tttggttcat gctcaagaaa
    22381 acaactcttg gttttgaaat ccgtgcagtt ggtcttaatc cacatgcttc agaatatgct
    22441 ggtatttctg ccaagcggac tattatccta tctatgatta tttcaggtgc cttggcaggt
    22501 cttggtggag ctgttgaagg tttgggaacc ttccagaacg tctatgttca aggttcgtca
    22561 ttagctatcg gatttaacgg aatggcggtt agtttgcttg cggccaactc accaattggt
    22621 atactctttg cagccttcct atttggcgtt ctccaagttg gggctcctgg tatgaatgcg
    22681 gcgcaggtac catctgagct tgtcagcatt gtaacagcgt ctattatctt ctttgtcagt
    22741 gttcattacc ttatcgaacg ctttgtcaaa ccgaaaaaac aagttaaagg aggtaagtaa
    22801 agatgtctat tataaccttg ctccccctct tggtgtcttc tatgctgatt tactcagcac
    22861 ctctcatctt tacaagtatc ggtggtgttt tctctgaacg tggtggtgtg gtaaacgttg
    22921 gccttgaagg aattatggtt atgggtgcct tttctggagt tgtctttaac cttgaatttg
    22981 cagaacaatt tggagcagca actccatggc tatccttgct tgtagcagga ttggttggta
    23041 gtgttttctc tatcatccac gcagcagcga cggttcattt ccgtgcagac catgttgtca
    23101 gcggtacggt attgaacttg atggcgcctg ccttggctgt tttcttagtt aaagttcttt
    23161 ataacaaagg acaaaccgac aacctaagtc aaacttttgg acgctttgat ttcccagtct
    23221 tggcaaatat cccagtgatt ggtgatatct ttttcaagtc aactagtcta cttggttatc
    23281 tggcgattgc cttctcattc cttgcttggt ttattctctt taagactcaa tttggtcttc
    23341 gtctccgctc tgtcggtgaa catcctcaag cagcggatac cttgggaatc aacgtctaca
    23401 agatgagata tttagggatt attatttcag gttttctagg tggaattggc ggagcgattt
    23461 atgcgcaatc aatctcagtt aacttctcag tgacaactat tgttggacct ggatttatcg
    23521 cccttgctgc gatgatcttt gggaaatgga atccaatcgg tgctatgctt tctagtctct
    23581 tctttggact ttcacaaagt ttggctgtta tcggttctca attgccgttc ctacaaggag
    23641 tgccagcggt ttatcttcaa attgcacctt atgttttgac aattcttgtc ttagcagcct
    23701 tctttggaaa agcagtcgca ccaaaagcag atggtatcaa ctacatcaaa tcaaaataag
    23761 catacaaaaa aacgtcagtc caatgactga actgcccccc aaaagttaga cagaaaaaat
    23821 ctaacttttg gggtgttttt attatgaaat taagttatga tgataaagtt cagatctatg
    23881 aactaagaaa gcaaggatat agcttagaga agctttcaaa taaatttggg ataaataatt
    23941 ctaatcttag gta
//
LOCUS       DAVLIK010000032        23742 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLIK010000032 DAVLIK010000000
VERSION     DAVLIK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.032"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(1..185)
                     /locus_tag="VXE87_001386"
                     /pseudo
     CDS             complement(1..185)
                     /locus_tag="VXE87_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001909937.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(165..314)
                     /locus_tag="VXE87_001387"
                     /pseudo
     CDS             complement(165..314)
                     /locus_tag="VXE87_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(468..2099)
                     /gene="rlmD"
                     /locus_tag="VXE87_001388"
     CDS             complement(468..2099)
                     /gene="rlmD"
                     /locus_tag="VXE87_001388"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0842920.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2173..3147)
                     /locus_tag="VXE87_001389"
     CDS             complement(2173..3147)
                     /locus_tag="VXE87_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0842921.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3221..3835)
                     /gene="pmp23"
                     /locus_tag="VXE87_001390"
     CDS             complement(3221..3835)
                     /gene="pmp23"
                     /locus_tag="VXE87_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0842922.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     QDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3835..4809)
                     /locus_tag="VXE87_001391"
     CDS             complement(3835..4809)
                     /locus_tag="VXE87_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0842923.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4817..6073)
                     /locus_tag="VXE87_001392"
     CDS             complement(4817..6073)
                     /locus_tag="VXE87_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0842924.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6135..6566)
                     /locus_tag="VXE87_001393"
     CDS             complement(6135..6566)
                     /locus_tag="VXE87_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0842925.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6568..7170)
                     /locus_tag="VXE87_001394"
     CDS             complement(6568..7170)
                     /locus_tag="VXE87_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0842926.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7154..7993)
                     /gene="prmC"
                     /locus_tag="VXE87_001395"
     CDS             complement(7154..7993)
                     /gene="prmC"
                     /locus_tag="VXE87_001395"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0842927.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(7993..9072)
                     /gene="prfA"
                     /locus_tag="VXE87_001396"
     CDS             complement(7993..9072)
                     /gene="prfA"
                     /locus_tag="VXE87_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0842928.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9069..9659)
                     /locus_tag="VXE87_001397"
     CDS             complement(9069..9659)
                     /locus_tag="VXE87_001397"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0842929.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            9782..9964
                     /locus_tag="VXE87_001398"
     CDS             9782..9964
                     /locus_tag="VXE87_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0842930.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10101..11474
                     /gene="mnmE"
                     /locus_tag="VXE87_001399"
     CDS             10101..11474
                     /gene="mnmE"
                     /locus_tag="VXE87_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0842931.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQIEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11521..12456)
                     /gene="dapA"
                     /locus_tag="VXE87_001400"
     CDS             complement(11521..12456)
                     /gene="dapA"
                     /locus_tag="VXE87_001400"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0842932.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12512..13588)
                     /locus_tag="VXE87_001401"
     CDS             complement(12512..13588)
                     /locus_tag="VXE87_001401"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0842933.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEKSTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(13931..14003)
                     /locus_tag="VXE87_001402"
     tRNA            complement(13931..14003)
                     /locus_tag="VXE87_001402"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13968..13970),aa:Thr,seq:ggt)
     gene            complement(14103..14612)
                     /locus_tag="VXE87_001403"
     CDS             complement(14103..14612)
                     /locus_tag="VXE87_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0842934.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14610..14706)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            14735..15166
                     /locus_tag="VXE87_001404"
     CDS             14735..15166
                     /locus_tag="VXE87_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0842935.1"
                     /translation="MKIPIQKFFNNEILAYLFFGIVTTLVAILLRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15248..15625
                     /gene="mscL"
                     /locus_tag="VXE87_001405"
     CDS             15248..15625
                     /gene="mscL"
                     /locus_tag="VXE87_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0842936.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15667..16761)
                     /gene="hemH"
                     /locus_tag="VXE87_001406"
     CDS             complement(15667..16761)
                     /gene="hemH"
                     /locus_tag="VXE87_001406"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0842937.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLCLSSKQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            16916..18139
                     /gene="pepT"
                     /locus_tag="VXE87_001407"
     CDS             16916..18139
                     /gene="pepT"
                     /locus_tag="VXE87_001407"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0842938.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIESIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18175..18804)
                     /locus_tag="VXE87_001408"
     CDS             complement(18175..18804)
                     /locus_tag="VXE87_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842939.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLEPTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            18769..18990
                     /locus_tag="VXE87_001409"
     CDS             18769..18990
                     /locus_tag="VXE87_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842940.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19127..19336)
                     /locus_tag="VXE87_001410"
                     /pseudo
     CDS             complement(19127..19336)
                     /locus_tag="VXE87_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad protein"
     gene            complement(19423..19686)
                     /locus_tag="VXE87_001411"
     CDS             complement(19423..19686)
                     /locus_tag="VXE87_001411"
                     /inference="COORDINATES: protein motif:HMM:NF016182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0842941.1"
                     /translation="MLEITLKSPYQFAHILFQPTIVPHGGHYHFIPESDLSAGELAAT
                     YVFNPNDIVRDTGDAYIVRHGVTITIFLSHLLTIPHHTLTRKR"
     gene            complement(19730..20290)
                     /locus_tag="VXE87_001412"
                     /pseudo
     CDS             complement(19730..20290)
                     /locus_tag="VXE87_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(20516..23104)
                     /locus_tag="VXE87_001413"
     CDS             complement(20516..23104)
                     /locus_tag="VXE87_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0842942.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTPSPSLPINPGTSHEKHEEDGYGFDANRIIAED
                     ESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSNAKE
                     MKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVGIGH
                     SHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVSFSF
                     PPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFKYTI
                     ASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDALVRV
                     FDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYIVEV
                     PILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTSNST
                     LEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTGEAP
                     QGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPEGNV
                     GSDPMLDSALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVIKKN
                     LSDLIA"
     gene            complement(23314..>23742)
                     /locus_tag="VXE87_001414"
     CDS             complement(23314..>23742)
                     /locus_tag="VXE87_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842943.1"
                     /translation="DHVRKNKADQDSKPDEDKEHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDEAEIPQVENSVINAKIADAEALLEKVTDPSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT         6783 a         4921 c         4359 g         7679 t
ORIGIN      
        1 tctttaaatt cattggtatg ctgcttacaa tatccattat taaaatggat actataaaca
       61 gcacaccaac tatttatttt ttgagtttta aactttggta gaagtcttga actccttata
      121 tttacataac tatttgcctc tataactatt atgacacgaa accaacaagc aagttcaagc
      181 acctccatat ctttattcaa atgaggacta agatattcac aaactttatc ataaacctct
      241 ttatcttttt tcataaaagg ggcatacaac ttagcaaatt tatcctaaaa ttttttgttg
      301 cctttatcaa tcatttcaac actcctttaa atataaaaat gatcctatca atctttatat
      361 tgagcctatt ttctaattga taccttgcaa gaaaggaata atagccgttc ctataccaag
      421 taggaatgta ataaatgcag aaagtcatat actgtcattc ttttctatta aatcattttg
      481 aagtgtctca aagcatccat gatggcttct tctttttcag gtgtacactg tggaataatt
      541 tgtttatcct ttttagactt gttgtaatgt tctcgtaatt ctattccaca tttctttttt
      601 atctgtgcaa tatataatgt cgaaactttt aattcaaatt tattccaaac atattctttg
      661 atttgagcat atgttgcttt gctctccgca cttgtcaaat tcatctcatc cagctcaatt
      721 tcaacactta tgtgcttatc gacatcgagt ttggacaaaa gtgctaccgt ctcgacgtga
      781 tgcgtttgag gaaatagatc caccggctgg actttcttca attcatatcc caattcttgg
      841 tagagtttga tatcacgcgc catggttgcg acattgcagg agatataggc gatgcgatcg
      901 gctcctgttt gggcgcttgc tttgataaag ctttctgtca agcccttgcg tggaggatca
      961 accaagataa cggttggttg aatcccatct ttaagccaat tcttcatagc attttcagct
     1021 gtgtcacaga catagtgggc gtttgaaata ttgttcaact gagcattttt tttactattc
     1081 tcaaccgctt ctggaatcag ttcaacaccg tagacttctt tgacatgctt ggcgactgat
     1141 aaaccaatgg ttccaatacc agaataagca tcaataacca cgtcatcttt ttttaactct
     1201 gcaaagtcaa tggctgtttg atagagtttc tccgccattt cagtattgac ttggtaaaag
     1261 gctgggccag cgatttggaa gtcatttccc aacatctggt ccgtaatata gtcttgacca
     1321 taaagagtgc gccactcctt accaaaaatc gcattggtat tctggtcgtt gatattttgc
     1381 atgacagaca caatctctgg gaactgcttg ataacttgtt caatcaattg gtcaacacga
     1441 aaaacttttg gacgagttgt caccaaaacg accatgattt gtcctgaata gtgaccacga
     1501 cgcaccacaa gattccgaat caatccagac tgttcctttt cgtcataagg ttttaaatca
     1561 aaacgacgga gcaggtctcg aagagctact acgacttggt caatgacagg atcctggata
     1621 aagaaatctt caaggggcat gaggttgtgc gaattcttac ggaaaaatcc tgtttccaag
     1681 acaccattca ctcgacgaac gggcacctgc gccttattgc gatacttgac tggatgttcc
     1741 ataccaagcg tttcagcaac ttctacatct gcaattccag caatcttgta gagactgtcc
     1801 ttgacttgct tggttttaaa cttgagctgt tctggataag aaaggtgtcc taaatccgcg
     1861 attcctgaac gcaggtaagc caaatctaga tcttgattac ggtgtggtga ctggacaagg
     1921 tatttttcaa cttttccaaa gccaatcttt ttattgacct tgaggacacg catgagaatt
     1981 ttttcactcg gtaaagcatt ctctacaaaa aagaccaaac catctacctt ggcaactcct
     2041 gccccttcat gggtcaaatc aacaatttca acttctacaa tatcattttt ctttaacatt
     2101 cttttctctt tctattggcc gacaaaaaag acggcaacgt tacggttacc atccattata
     2161 ccatgaaatt tcttaagaac caaaactctt gaagaagttg acaagggctt gccagaggga
     2221 gcttaagaag ttaccaccgt cctctagcgc cttatccgca tcaaagttaa ggttgatatt
     2281 tttaaaactg tcgccagctt gtgatacgat gctttgttta aggtcattta gggttttagt
     2341 gaaatctgca ttgctgagga tatcactctt tgagagattc aaggcaaaat tgatgatgat
     2401 attgatctgg tttcctgtta tgacctgatc aagtttgtaa ttttttaagg tatcttcaac
     2461 aatcttgcgg atatcttctt ctgtcagatt tcccttgctt tctttagctt tggcgagtcc
     2521 tgacttgata tcagctaggg caacgtttaa tttattagca tcatagcctg atttgtcctt
     2581 gttttcagca ttgatatctg acaaagcctt tagctcttct tgagccaaat ctttattggc
     2641 ttgcggcacc ttggctccat tagcttctag cgaatagtag atcccagcca aagcactctc
     2701 acctgtaact ggaatgggtg ctgctacagt gattttggcg tgttccacac ccaaagttac
     2761 ggctgcattt cggtacatat cctgagttac cttagtgatg ttttcaggtg tttcaatctt
     2821 gacctcaagt ggcgatttgt cacctagctt ttgaatcttg gctgatgaat acaactgtaa
     2881 gctagagtca ttggccacat tcatgatttt agaataaaca tcaggtgtca tggtcttgag
     2941 ttctttggta tctgttgagg cattgtagcc cagtttttta agagtttgat ttttttggtc
     3001 ttcagatagg gaagaaccta ggacatattc aggttggaca taggtttcat cgataacttt
     3061 ttgaacatct gttgctgcat ggacgctatt catagctgtt actgcccaca agatcgcagc
     3121 gctagtcaga aagagtttct ttctcatagg gaatttcctc ctttacttct ttagagtaat
     3181 atatctatct taaagaaaac ttataacaaa aacacctggt ctagccagat gttgaaaaga
     3241 gagtgaaaca tttgataatg taaaggttaa gtcgtacctg tctagaataa taatagtttc
     3301 ctccatttac atagagttca gcaccgtgaa aaatggaaat ggggtgaata taactataag
     3361 tctttccagt cgtattacca agcaaggggg caacagtctc acgagagtac tgtttggcta
     3421 gagccaaggt attttccttg ccattttggg cgataaaatc gatataggca ggtccaaaat
     3481 tataggcttg aacagctgtc cagatatcta cacccttctt ctgcgccaga tagagattgc
     3541 ctgtcagagt ttgaatgcct tgccgaatgc tagaggcatt atcattgatg gtgttggtgg
     3601 aaccacttgc agactcacta gactgcataa catcgccttc ttttcctttt gtttcagtat
     3661 aaatcatagc aagcacaagc tcttcgtttg ctggggtgtc ttgttcactc aatatttctc
     3721 gcaccatggg ttgataggtc atgacttgtt tgacatcttg atgaacgcgg taagctttat
     3781 agccagcaaa aaggaagact gctagtacaa gcactcttcg aattcgttta aacattattt
     3841 actttggata tcctcgatat ttttgattaa gatagagtag gttccatttt cgttttggat
     3901 aaactcaaca gactcggcgt cttgatagac gttattggga acgatgagct caattccatt
     3961 tgataaggag agtttttggt tttcaaattt ctttaattgg cgactggcat caatttcatc
     4021 aaattgaaca ggttctggta cggcttcttt gacttggtca ataaagctca aacgagccgt
     4081 cagattgttg tcaaaaaggt cattagccaa tttctcaggt gacaattcat tgctttcttc
     4141 taggttgttg aaaatagctg atttgacctt ggattgaaat tgaaaatcat ctgtgttaaa
     4201 agattcagca attctctggg ctgttttttc cagttccttg atagattttt taggagaaat
     4261 cttaggagcg acagcaagaa gattatctga aaaatagttc aaaaaagtcc cgttgtactt
     4321 gattcgtttt tcaatcaggt gatacttgcg actctgaaga ttgaccacca aggcctcgtc
     4381 agcacccgtt ccaaatccag gcaggttatt ctgagtcagc ttgattggat tatcaacttc
     4441 tcctccgagg tgggtcaagg tctcccgcag ggcaattcgc aagaaagcga aatgttctac
     4501 accttcttta gaaaattgaa caaaaatcaa gtcattggtc ttgagatttt cagaaatgct
     4561 aaactcctct ttccagagat tagccagcgt tactgatgtc tccaacaaat cgtctgtaat
     4621 atgattgaag aagggatttt cttcttcgaa aatcccagtc ttggcttcat ctgaatacac
     4681 atgttcaatt tttttacgta ggtattcttc gatttttgga gtaatattga gaaacttatc
     4741 tgctaagaac agctcggtat catccggact gaactggtga ataatggctt tcttaatata
     4801 aatgtccata aaagttttat tcctcgtata atgggaaggc atctgtcaat tctttgactg
     4861 cacttctcac ttcttctaat acagcctcat tttctgaatt cttaagggtt ttaatgatga
     4921 gttcagccac tttgcgactt tcttcttcac caaatccacg tgcagtaata gctgctgctc
     4981 cgatacgaat cccacttgtc ttgaatggtg acaaggtttc gtaagggatt gaatttttat
     5041 ttagggtaat attgacttca tccagcaagt tttgagcaac ttttccgttt tctacaacct
     5101 tagtcacatc aacaaggaag agatggtttt cagttccacc tgaaataata cggaaatcag
     5161 ggtcttgcaa gaagacatct gccatagcct tgctgttctt aattacattg gcagcatatt
     5221 ccttgaaggc tggatccaaa acttctttga aggaaactgc cttagccgcc acaacatgct
     5281 ctaaaggacc gccctgaata cctgggaaaa tagctgaatt gattttttta gcaagttctt
     5341 cgtcattggt caaaatcaaa ccaccacgag gtccacgaag ggttttgtgg gtcgttgttg
     5401 tagtgatatg agcgtatggc actgggcttg ggtgaagacc agctgcaacc aagccagcga
     5461 tgtgggccat atcaaccata agcttcgcac cgacagcatc tgcgatttca cggaattttg
     5521 aaaagtcaat aatttgagaa taggctgaag caccagctac aatcagtttt ggttttactt
     5581 cttgggcttg tttcaagata gcatcaaagt ctaagagttc cgtttcagga tcaacactat
     5641 aagaaacaaa gttgtaggtt tgaccagaga agctaacagg agccccatga gtcaaatgac
     5701 cacctgatgc caaatccatt cccataaccg tatcacctgg ctcaatcaag gacatgtaag
     5761 ccgcacagtt agcttggctt cctgaatgtg gttggacatt ggcaaattta gcaccgaaaa
     5821 tttcttttgc gcgttcaata gcaagagtct ctacaacgtc tactacatca gttccaccat
     5881 aataacggcg tcctgggtaa ccctcggcat atttatttgt caagatagac ccttgagctg
     5941 ccataacagc cttggaaact acgttttccg aagcaattaa ctcgatatta ttttgttggc
     6001 gttcttcttc tttggcaata gcattccaga gatcagcatc atatgcttta aaatcatctt
     6061 tgtcaaaaat cataggtctt ctcctttatt gtgtgactag tccattagtt tgattttaca
     6121 ataagaaaat caaactaaaa gatgcgaata aaccgtttct gcattttatc acaagtatag
     6181 ccaacttttt cataaaatgc atgagcaccc agacgatgat tggcagaatt taagcggata
     6241 aacccataac cacatctttt ggcttcttgt tccaaccctt gtagtaaact tttaccgata
     6301 ccttgacctt gcgcttgagg tgaaactgct aaagctaaga tattaaatcc tgctttggaa
     6361 tagagtgatt cgtaaacttc agcgtggaca tatccaagta agacatgatt agctgcatcc
     6421 tcatagccaa gtaggaaatg atgggaatcc tgagacagtc tagctagttg gctagccgtt
     6481 tcctctggac taaaagtata acccaaagcc tcttggttga tgtcacatat cgctttcaca
     6541 tctgtttctt gcaaatctct tagcatttca agcctcctca aaagaaatct ctggcaaccg
     6601 agcaagaata tcttctcgtt taattgcgcc ttggcgtaag attttcacct tgtctccaga
     6661 caaatccaca atagttgaat cctgtccagt tagaaaagca tcgtcttcca gacccagaac
     6721 ctcttggtca aaatccttca gaatttgttc aaaggttaca ccacttgcct gacctgagat
     6781 attggcagac ggcccaatca agggacctgt ctctcgaatt aaatccagtg tgatagggtg
     6841 actgggcatc cgaaatccaa tagttgcaag gtcagaattt acccaatagg gaactcggtc
     6901 attggcttcg agaataatgg tcaagggacc tggcaaaaag gtctctacaa gtttttgtag
     6961 ataagttggc tgattcttag aaaagtgcaa gatatcctcg aaagaggcga tattgagatt
     7021 gagtgcctta tctctaggac gacgtttgag ttggtaaaca tggtcaactg ctttttcatc
     7081 taaggccttg gcaaaaagac cataaacagt ctctgtaggt agaacgacag ctccaccatt
     7141 ttccaactct tgtctaatcc tgtccatcat caaccacaac catcctattt tgaccaaatt
     7201 ggtctttgag tgttcgaact tttttttcag gaagatgttt tctaaaaagt tcgggaacac
     7261 tttgaccttg cttgtatcca atttcaaggt aaatcttacc accatccttg agatagtctt
     7321 ttgcatcttc cgcaattcta cagtaaatag ctaggccatc ctcgtctgca aagagagcta
     7381 gatgaggctc cgaatgcaaa acattcaagc ctacctctga ctcatcttca cgagagatat
     7441 agggtggatt ggatacaatt atatcatatt tttcagaaat ttctgcaaaa caatcagatt
     7501 ttttaaaaaa tatattaaga ttttgatcgc tagcattctc tgatgcaagc tctaaggcct
     7561 cttgagaaac atctgctgct gtcactgacc aatctggtct attttttgct agagcgagag
     7621 caatagctcc actacctgtt ccaatatcca gaactgagag attcgtctca agattttcag
     7681 ttagaataag ctccactaac tcctctgttt ctggacgagg aatcaaaacc cgttcatcca
     7741 cctttaaatg cattccataa aaatctgcct gtccaatgat gtactgagct ggcttgtgag
     7801 ctgctagttg ctggtaaata tcttctacaa attgtttttc ttcctctgtt gtcacctcct
     7861 gctggagggc aaaaataaag tctgtaaaag atagattttt cagactacga tagacaaaag
     7921 agaggctttc cgcttcctct ccttgtctta tcaactcttc ttcaaaattt gaaaataatt
     7981 gagctaattt cattatttgt ttaattcttc tagtttttgt gtttggtcat aaagcaccaa
     8041 ggcatccaca acttcgtcca atttaccaga caaaatcgta tctagttttt ggagggtcaa
     8101 gccgatacgg tggtctgtga cacggttttg agggaagtta taagttcgga tccgttctga
     8161 acggtcacca gtaccgattg tcgacttacg ctcagcgtct tgttcatcct gagcaatctg
     8221 agcaaagtgg tcagcgacgc gtgcacggat aatcttcata gccttctcac ggttcttctg
     8281 ctgggtacgt tcttcctgca tctcaacctt gatattggtt ggcaagtgaa cgatacgaac
     8341 ggcagtcgca accttattga cgttctgtcc accagcacct gatgcgtggt aaatatcaac
     8401 acgaagatct tttggatcga tatcgtattc tacttcttcg acttcaggca tgacaagaac
     8461 tgtggcagtt gaggtatgaa cacgaccttg gctttctgtc acggggacac gctgcacacg
     8521 gtgggcacct gattcgtact taagcttaga gtatacagac tgacctgaaa ccatagcaac
     8581 cacttcttta aacccaccga caccattcat agaggcttcc atgacttcaa agcgccagcc
     8641 ttgggcttcc gcatactttt ggtacatagt tagcaaatct ccagcgaaaa gtgccgcttc
     8701 gtctccacca gctgctccac ggatttcaag gatgatattc ttgtcatcgt ttggatcctt
     8761 tggaaggagc aaaattttca gtttttcttc atattcttct ttttcagcct tggcatcttt
     8821 gagttcttgc ttggccattt cttccaagtc cgcatctccg cctgattcct taatcatctc
     8881 ttcggcatcg acgatatttt gaaggacttg tttatactca cggtaggcta ttacggtatc
     8941 acgattggaa gcttcttctt ttgaaagctc cataaaacgc ttggtgtctg aaacgacatc
     9001 agggtcactc agcaattctc ctagttcttc ataacggtct tctacagctt gtagttgatc
     9061 atagatgttc atttttcttc attctcctta ttgatttcag gggcaaaata atgtttacgg
     9121 caaaccgaga tataggtttc attaccacca atttggatct gttctccatc gtaaacgggc
     9181 agtccatcct gtgttcgcaa caccatggtc gcctttttct tgcaatactg acagatggtc
     9241 ttgatttcgt caatcttgtc tgctaaaagc aagagatatt tggaaccttc gaacaattca
     9301 ttgcgaaagt catttttcaa gccaaaagcc atgacgggta tgtctaactc gtccacaaca
     9361 cgagctaggt cataaacatg gtggcgtttg agaaactggg cttcatcgac caacacacag
     9421 taaggttttt ctggtaggcc tcggatatag ccaaagatat ccgttgtttc ctcaatcgca
     9481 agggcagggc gtttcatgcc aattcgactc gacacatagc caacaccgtc acgcgtatcc
     9541 agagctgaag tcataatcac aacacctttt ccttgctcct catagttata ggccaccttg
     9601 agaatctcga ttgtctttcc agagttcatg gtcccataac gataatacaa ctgtgccatg
     9661 tttcttgctt cacgtccatt tctaaatttt tgctacattc tagtatatca taattttctt
     9721 aagctttaaa cggcaaaatg tggtaaaatg gaagaaatca aaactagtgg aggaagctat
     9781 tatgccattt gtacgcatcg atttatttga aggacgcacg ctcgagcaaa agaaagctct
     9841 tgctaaggaa gtaacggaag cagttgtccg caacactgga gcccctcaat ctgctgtcca
     9901 tgtcatcatc aacgacatgc cagaaggaac ttacttccca caaggggaaa tgcgtactaa
     9961 ataagctagc ttaagcagaa ttgcttaggc tttttcaatc tccaagtagc attcattgaa
    10021 gaaatatcct aaatttgtta caatttgaaa agaaacttgg agaatttcca agaaaatagc
    10081 tattaattaa aggaaacatt atgattacac gtgaatttga taccatcgct gctatctcta
    10141 ctccactagg tgaaggggct attggtattg tccgcctgag cggaacagac agttttgcta
    10201 ttgcgcaaaa gatttttaaa ggaaaagact tgaacaaggt tgccagccac actctcaact
    10261 acggtcacat tattgatcct ctgactggta aagtcatgga cgaggttatg gttggggcta
    10321 tgaagtctcc aaagaccttc actcgtgagg atattatcga gattaacacc cacggtggta
    10381 ttgcggtgac caatgagatt ctccagctag ctatccgtga aggagctcgg ttggcagaac
    10441 ctggtgaatt taccaaacgt gcctttttaa acggtcgcgt agatttgaca caggccgagg
    10501 cggtgatgga tatcatccgc gccaagacag acaaggccat gaacatcgcg gtcaaacaac
    10561 ttgatggttc cctttctgat cttatcaata atatccgtca agaaatcctt aacacacttg
    10621 cccaaattga ggtcaatatc gactatcctg agtatgacga tgttgaggaa gccactactg
    10681 ctgttgtccg agagaagaca atggagtttg agcaattact aaccaagctc cttaggacag
    10741 cacgtcgtgg taaaatcctt cgtgaaggaa tttcaacggc tatcattgga cgtcccaacg
    10801 ttgggaaatc aagccttctc aacaacctct tgcgtgagga caaggctatc gtaaccgata
    10861 tcgctgggac aacacgagat gtcatcgaag agtacgtcaa catcaatggt gtacctctca
    10921 aattgattga tacagctggt attcgtgaaa cggatgatat agtggaacaa atcggtgttg
    10981 agcgttcgaa aaaagccctc aaggaagcca acttggttct actagtgcta aatgccagtg
    11041 aaccactgac tgcgcaagac agacaacttc ttgaaattag ccaagatacc aatcgcatta
    11101 ttctacttaa taaaaccgac ctgccagaaa cgattgaaac ttcgaaacta cctgaagacg
    11161 ttatccgtat ttcagtcctt aaaaaccaaa acatcgacaa gattgaagag cgaatcaaca
    11221 acctcttctt tgaaaatgct ggcttgattg agcaagatgc tacttacttg tcaaacgccc
    11281 gtcacatttc cctgattgaa aaagcagttg aaagcctaca agccgttaat caaggtcttg
    11341 agctggggat gccagttgat ttgcttcaag ttgacttgac tcgtacttgg gaaatcctcg
    11401 gagaaatcac tggggatgct gctccagatg aactcatcac ccaactcttt agccaattct
    11461 gtttaggaaa ataagaaaaa tccatgatcc ttcattcggt catggatttt attgtcttta
    11521 ttagtaatct ggtcttaaga cccctgttac agttgcctta gttgcttcgt agtcgccatc
    11581 tacgacaacc ttgataatgc gtttggcatc ttcttctggt gctggaacaa gaggtagacg
    11641 agtgggtcca gcttcaaatc ccatatagtt aagaattgcc ttaactggag caggacttgg
    11701 ataagagaag agagcattaa ccttaggaat gaatttacgc tgaattgctg cggctttctt
    11761 catatcgctt tctgcaatgg cagtaaacat ctcgtgcatt tcatccccat ttgtatgaga
    11821 ggcaacagaa ataaccccat ccgccccaag gttcatggca tggaaagcat ctccatcctc
    11881 acctgtataa atcaagaact cttcaggctt gtgctcaatc aagtaagcca tattagccaa
    11941 gctagtacat tctttgacac cgataatatt tggatggtca gccaagcgaa gcatggtttc
    12001 tggagtcaat tcgacaacta cacgccctgg aatgttatag ataataattg gtaggtcaga
    12061 agcatctgca atagtcttaa agtgctgata catcccttct tgagaaggtt tgttgtagta
    12121 aggaacaata gcaagcccag ctgcgaaacc accaaattcc gctacttctt tgacaaactc
    12181 aatagagtca cgcgtatcat tagtacctac acccgcaatc aaaggaacgc gtccattgac
    12241 aaccttttgt acagccgcaa acaactccaa ctcctcatcg tgggtcaaag ttggactctc
    12301 agcagtcgtt cctgcgagaa gaattccatc cgtatgatgg gccaataaat gctcaatcaa
    12361 ggctggaata gcatcaaagt taatagaacc atcctcatga aagggggtaa taaaggctgt
    12421 aatgatttta cattctttta aatcttgata agacatgaaa acacctctct atttcaaaga
    12481 aggagttcat ctgaactcct aaacgatatg actattttaa ttcaaatttc aattcggctg
    12541 ttggacgaac caatccacgt tcatgaagag tttcagcaat ctgaactgag ttccaagcag
    12601 cacctttgag aaggttatct gaaacaaccc acatgtgaat tcctttttct gcatccaagt
    12661 ctttacggat acgaccaaca aaggtatcac gcgaaccaac tgcattgata gcttgaggat
    12721 agatttgatg agctacatca tcttcaagaa cagcacctgg gaaggctgcg atagctgctt
    12781 ttacttcttc gattggagcc acttcttttg tttcgatata aacagactca gagtgagctg
    12841 acaagactgg aatacgcaca catgttgcag atactgcaat gctatcatct tccataattt
    12901 tcttagtttc cttggtcatc ttcatctctt cgtaagtgta atcattgtca gtgaagacat
    12961 cgatttgtgg aagagcattg aaggcgatag gataatgttt cttgtcaccg cctgaaggta
    13021 agatttccgc atgcaaatca cgtggtttca ctccatcatt caagacctca cgaagttcac
    13081 gttgtgtctc aagaattgct cccataccag cacctgaaac ggcttgataa gttgaaacaa
    13141 tgatacggtc caagccccat ttttggcgaa ccggctcaag agccaccatc atttggattg
    13201 ttgaacagtt agggcaggca atgattccgt tgtgggcatc aagtgcatga gcattgacct
    13261 ctggaacaac caaaggaaca tctggatttt gacggaaata agatgtatta tccactacta
    13321 ccacgccagc ttttactgcg tatggtgcat acttagctga tgtcgaacca cctgctgaaa
    13381 agagagcaat atcaactcct tcaaaagctg tttcagtcgt ttcttcaatc gtaatatctt
    13441 gatctttaaa tttcaatgac ttacctgctg aacgtgcaga agcaaggtaa cggattttat
    13501 cgattggaag tgttgatttt tccaacattt ttatcatctg agcaccgaca gcacctgtcg
    13561 cgccgactac agcaactgta tatcccataa ataacctctt tcggaatttt ctaaaaattt
    13621 ctataataga agtattatac tactttttcc atgaattgca aagctttttc atcatttttt
    13681 ggaaaataaa aatccccaat cgctagacta gggattaaga ggcatcttca tgtgatgagc
    13741 aggttcacac aactcatcaa ggtccgctcc tgcgttatga cctccttatg ctcaatagta
    13801 gcccgaagac tacctatcga ctcatcgcat attctatatt actagagata gttgattttg
    13861 tcaataagaa attttttcga tcgagtataa caaaaaactc tcgtattcaa gagtttccct
    13921 atacatatca tgctaattgc cgggattgaa ccggcgacct catccttacc atggatgcgc
    13981 tctgccaact gagctaaatc agcttactta agaagtatac tatattcaga aaaacttgtc
    14041 aagtttcctt agaaattttc cataggaaaa agccaggtaa gaactaccta gcttatcttc
    14101 ttctatttac ttaaatcaat tcgacgacca attttaccaa taataatcgc cccaataatc
    14161 aatgaagcaa attcaccgat tcctgttgta aaccaagtaa ggaagaatgg taattctgct
    14221 acaatattta actctgcagc gatagtaaac atggaaattg aaaagaggat tgaaaagaag
    14281 aaatgatctt ttcgaatcaa tccgttaaag aggtaatcct tgctatattt tgcaaaaagc
    14341 caaacaccta aactgaggaa tactaaggtt gaaccaccac caacaaagac atctagcagt
    14401 ccgaagctaa agaaattagc aatcatacaa ccgatggtaa ctccgatgat gtacttagga
    14461 ttgtaaaaag ccataaagtt catcatttct gaaatacgaa actgataagc accatagctg
    14521 atggcattta ggggcggtgt gacagtcaaa acgacgtaga tagcagcgac gattgcaata
    14581 tctgcaacat cacgaatagt taattttttc atcttttctc ctttggcggt tgcccgcgtg
    14641 taatatgctt ggtgaaagaa gctaagcacc aagggttgct ttattcaacc ctactagtat
    14701 agcacaatag cctgctttat gctatactta acacatgaaa attcctattc aaaaattttt
    14761 taacaatgaa atcttagcct atctcttttt tggtatagtg actactcttg ttgctatact
    14821 attacgatta gtcatttatc agctaagtca tcaagaactc cttgctacgg ccttggcaaa
    14881 tattatcggt attttatttg cctttatcac aaatgataca attgtattta agcaaaaaaa
    14941 gaaaaataga cttatccgtt tagtgaaatt ttctcttgct cgcctttcta cttttctgtt
    15001 agacttgttt ttaacttttc tctttgtaac ccaatttcct cacatcatag ggcaattcgt
    15061 aactgaaaac attgataaga taaatgctat tgaaacaata attgcacaaa tattcattat
    15121 tatcatcaat tatatcttga gcaaggtcta tatttttaga aaataatgct ccatttatga
    15181 gccttttaat tgccttctat aatgatttag gatacaatga aacacgaaac attgaaagga
    15241 aaacagtatg ttaaaaaatc taaaatcgtt cttgcttcga ggaaatgtta ttgaccttgc
    15301 tgtcggtgtt gtaattgcct ctgcttttgg tgctatcgtt acttcacttg taaacgacat
    15361 tatcactcct cttattttaa atcccgcttt gaaagctgct aaagttgaac gtatcgctca
    15421 actttcttgg catggagtcg gctatggtaa cttcttaagt gctattatca attttatctt
    15481 tgtgggtacc gccctcttct ttattatcaa gggcattgaa aaagcacaga aactgactgg
    15541 cataaaggaa gaaaaaactg ccgaaaaaaa accaaccgaa ttggaagtcc ttcaagaaat
    15601 aaaagctctc cttgagaaaa aataatcgat taaaaggatc tagcgcaaag ctaaatcctt
    15661 ttttctttac tctttgggta acttgcctgc tttttcaagc atttttttga taagataagg
    15721 catcttaaca ttctcccgcc cttttttctc aatcagtttt ttcacaaatt ctggcatttg
    15781 taaatcttca gattcagcca aaatgttttt tgtctcgtct gaaggaacta actcatcaaa
    15841 ggtctcttct tctgggagaa attccttaaa ctcttgattt tcattgactc taactgtatt
    15901 gaccaaagca tcaatcaaac gagaatctgt atttggcatt ggtggacgat ggtagtttac
    15961 cccaaattcc tgacataaat cataacattc cacatcattg tcaaacaaga cctcaatatg
    16021 ctcactgatg aaactaatag gtacaaaaat ataatggtct ggatgttctg tctgttctct
    16081 gagatactcc aaaacatctg gtttaatcca tggaatacca atatcactct cactctgcca
    16141 agtgttagta tattgttttg aactcaagca cagtttttca gcgactagct tgctattttc
    16201 gaaaatttgg tctatataag gatcaccaaa gtccaaggca aaaataggca cactatgggc
    16261 tgaaaagatg actttaaagc tgtcttgctt tacttcttct tttaaaatct tagcaatttc
    16321 atctgcccaa tagtttaaga gcgcttcttc ctgataccag tccttaatga ccaaaaattg
    16381 aatttgtttg ctttctaaaa atttttcata gcccatgaca gagtagaaag aataatgggg
    16441 ctccaaaatc aagcaaatac actgttcaat tccgtctgct tccatttgac cgatcacatc
    16501 tggaataaag ggactggaaa acttattagc aaagtagaca ctgtattcat tccccagcct
    16561 agcttctacc aaggcaacct cttgacgggt aattttttgc agaggcgtgc ctccaattcg
    16621 tacataatta tcatagagag tctgaatctc gtggtcttgg ggtctcaccc cacgacgaat
    16681 atttgtgaaa aaatcagcta caccttcaaa ggtaatctct tctggtgaac cgaaggtcat
    16741 cattaaaatt gcttttttca tgactgcttc cttgtgatgt ttttatcaag tttattttat
    16801 cattaattca tcgataagta aacgctagca tagggacatt ctcaatcttc tgtcttttgt
    16861 ttttctcttc tttctatgat acaatggaaa aaataaattc aaaaggagtt tttttatgac
    16921 ttatccaaat ctcttggacc gcttcttaac ctacgttaag gtcaacacgc gctctgatga
    16981 acactctact actactccaa gtacacagag tcaggttgac ttcgcaacaa atgtcctaat
    17041 tcctgaaatg aaacgtgttg gactgcaaaa tgtttactat ctaccgaatg gttttgctat
    17101 tggaaccttg ccagccaacg atccgtcttt aacacgtaag attggtttta tatcgcacat
    17161 ggatactgct gattttaatg ctgaaggagt caatccacag gtaattgaaa actacgatgg
    17221 tggtgtgatt gaactaggga attctggttt caaactcgat ccagctgact tcaagagtct
    17281 tgaaaaatat ccaggacaaa cgctcatcac aacagatgga acaaccttgc taggtgctga
    17341 tgacaagtca ggaattgctg aaattatgac agccattgaa tatctaactg ctcatcctga
    17401 aattaagcac tgtgagattc gtgttggttt tggtccagat gaagaaatcg gtgttggtgc
    17461 caataaattt gatgcagaag attttgatgt ggattttgcc tacactgttg atggtggtcc
    17521 actaggtgaa cttcagtacg agactttctc agccgctggt gctgaattgc atttccaagg
    17581 ccgtaatgtc caccctggta ctgccaaagg gcagatggtc aatgcccttc agctagcaat
    17641 tgattttcat aatcaacttc cagaaaatga ccgacctgag ttaactgaag gttaccaagg
    17701 tttttaccat ctaatggatg tgacaggtag tgttgaggag gcgcgtgcaa gctacatcat
    17761 tcgtgatttt gaaaaagatg cctttgaagc gcgtaaagca tccatgcaat ctatcgctga
    17821 taagatgaat gaagaacttg ggagcgaccg tgtcactctc aacttgacag accagtacta
    17881 caatatgaaa gaagtcattg aaaaagatat gactccaatt accattgcta aagccgttat
    17941 ggaagatcta ggtatcacgc ctattatcga atcaatccgg ggtggaacag acggctctaa
    18001 gatttccttt atgggaatcc caactccgaa tatctttgca ggtggcgaaa atatgcacgg
    18061 acgttttgaa tacgttagcc ttcagactat ggaacgtgca gttgatacca tcattggcat
    18121 cgtagcttat aaaggctaaa aagacgaggt ggctcagcta cttcgccttt ctttttattc
    18181 tactggtttt tcttgatttc cagtagttgt agaagattct gttgtttcat tttctgaagt
    18241 tgattcagca ggtttagaat ctcttgtatt gcttggtttg ttttcgtcgc tagcagtttc
    18301 aatgttagat tctgcagttg cgtttggttg gttctcagca ctggtgttat caccatttgc
    18361 ttcagcattt cttgctggac ttgtttcttc acttgcgcta gcttttgact ggatttgatg
    18421 attcaaaact agaatagctt ttgtcggttc aagtaaagct gttttgtctt tactcttagc
    18481 agaaagttga tctaataatg catccacctt atcaaagtcc gcatcagatc cattattact
    18541 ttctaaataa gagtgaagcg acatgagaat atcgtagagt ttttgataga gtacaagtgt
    18601 ctgaggatct tgctcagcat tttccttttc ttgttgaagg gcgctagcga tacgagtcaa
    18661 aacatctttt acctgactgt ttacttcatc caagtctgca tcagccttgt ttgtggcagc
    18721 ttttagattt tctacttctt ctgccaagga ttgtctgatt ccttcttcat ggatttgttc
    18781 caagagttga tttgccttgc tcaaaagact ttctacttct tccttgctat ctgtcgcaga
    18841 ttattggttg ccatctacca tgtactccta aaacaggaga gttataatcc aagattacaa
    18901 ggccttacag aaataagaaa tccagataag acaatgttcg tccaagacgc tattcgcttc
    18961 gcacagcagc acggattcaa tatgctttaa ttttaaagtt taggtgtcaa gacctctttt
    19021 tagtgtgccc aaaatttaga gaagtaatca atcaactaac ttttattttt ttcaaacttt
    19081 cagtaaactg acctaaagct aactcaatct gtctttgttc gataggcttg tctttgtaga
    19141 tgcttctgct atcagctaga agttgatcta cttttgccaa gactgccttc tcataaaaag
    19201 ttccaggttg atagttggat tgcagggatg gaatcttgtt tttcaaagcc gcttcatatc
    19261 ccttagtttg aaccttgatg tagtgattgt ggtcgccacg aggaatcaca aaaccttctg
    19321 aatcttcact tataattcga ttggcatcaa aaccatgacc atcttcttcc tcatggtgga
    19381 catgtagtga cggattactt aatacagaac tagaagaact tcctaccttt tccgtgttag
    19441 agtgtgatgg gggattgtta agagatgact taggaatata gtgatagtga ccccatgtct
    19501 tactatataa gcatcacctg tatctctgac aatatcatta gggttaaaga catatgtggc
    19561 tgctaattca cctgccgaca agtcactctc aggaatgaaa tgatagtgac caccatgtgg
    19621 tactatagta ggttgaaata gaatatgagc aaattgataa ggggatttta aagtaatttc
    19681 taacaatgat ttagaaacta tgatgtgcta ttctaaattc aactcactat atataaccat
    19741 catcggtagt ataacgtccc tgtaattttg ctacagatac ttctgcacta gctcctttat
    19801 cgtctttacc atgttcttgt ttttggcgat tgatttcatc ttttgttcgt acattttctg
    19861 catgagcttg atctttaagg taaacataat actttccatc taccttaata atatatcctc
    19921 ccttaaccta actgacaata tcttgatctt tcggctgata gttgggggct ttcattaatg
    19981 gctcttcact aaagagcgca tcaaaaggaa ctttaccatt atagcagtga taatgatcgc
    20041 catgagaagt tacataacct tgacctgtaa tcttaataac aatttgtttt gcttgaattc
    20101 cttctttttg actaacctag tctggagtca aattttcagt cttcttagtg tctttattac
    20161 tgtttacata tgaaacacga tttttatctg tattggcctg ttagctatgt tggttcagag
    20221 cataaacaca cagacttaag gaaaggataa caacagatcc agctgctata tatttctttt
    20281 taaatttcat aattacctca tttctataat tatttatatg atgtcttcat tattaaatga
    20341 ttatagaaat taattaacca attaattaac tagtaaatat tccacctctt tttaagttgt
    20401 atgtcaagaa attttatata ttaataataa aatgaaattc tcccaaagtc agagttttat
    20461 ttctaacttt tgagagaact tcatttttga ttcagacttt ttctactgct attccttacg
    20521 ctatgagatc agataaattc ttttttatca cttctccact tggcaatctt aattcaatcg
    20581 ttccatccat attgaatata acactatcta agcctaatcc gtaactagct gtaaattttt
    20641 ctaatttttc ttgtacagga tctactgctg gagcttcctc taatgctgaa tctaacatag
    20701 ggtcactccc cacattccct tctggattca acattccatt atccgttgag ttttctggtt
    20761 ttacaggttt ttcgtttggt gcctctggta aagaatctgc tggtttattt tctgttggtt
    20821 ggttctcaac tgttccagta gatacttttc cattttcaga tggtttattt tcaccatttc
    20881 cttgaggtgc ttctcctgta aaatctgcca tattcttttt aatgacttct cccgatggta
    20941 aatataattc aattgttccg tccatattaa acaagacatt ttctagcttc atcccataac
    21001 tttcagcaaa ttttgctact ttttcttgta caggatccac tgtaggaact tcttctaacg
    21061 ttgaattact agtactattc ccagtttcag aaagtttttc tttttctacc ttctcactag
    21121 tctttggttc ttctaccttt tcatcaagtt ttgagttttc ttgtgcttta ttccttttaa
    21181 attgtggtag aatacttggt ttatcagttt gattttcttt ttccaagata ggtacttcca
    21241 caatataagt cgattgattg tccaaataag catttgccat gaaggttaca ggaattttat
    21301 ttccggccgt tctggttgtt ccttggttta atttcggaat cggtaatttg atttcaccaa
    21361 ctttatagtt attttctaaa taagcatttc catgaaattc atcaaacact ctgactaaag
    21421 catcagttcc tttaggcact gcaaattgag ggttcactct taaataagta tcccctgcat
    21481 ggaaaggata gaaaatcgtt tgactggcca ttttgtaagc taaagaggtt ggaactgtaa
    21541 atgtaccatc ataacttact tctggataat cttttgaagc gatagtatac ttaaatgttt
    21601 gtcctggtaa ataaggttga tctaattcaa agtttgcaat attccctact ccttctccaa
    21661 atactttacc agatactttc tccaatactt ttccatctgg tgttattaat tttactagca
    21721 tattgatacc taattttttc tccaattcag gcggaaaact aaaagaaacg cgtttttgac
    21781 cattggctag agtaaagttt tgattattaa acgtactatt ttttaacaaa ttaacaacat
    21841 tcgttaattc ttctccagta taaactttat tcccttcttt tttagcaact ccttcttcgg
    21901 gtttaaacag ttcatagtta ctgtgagaat gaccaattcc aaccggttta tgttcatcaa
    21961 tcggatctgc atgatggtga tctccatgcg gataaataat cgcatttttt tctttattca
    22021 cgacaatact ttcacgtttg acaccatatt gtttcataat gccagcaatt ttttcttcga
    22081 tttttttatc taaatctttc atttctttgg cattacttgg ataatcctgt tcatgagatg
    22141 acaaagaatc taatccatta tgactagttt taacttcctc taaatgtttt tgcgcagcct
    22201 taatttgctc ttctgtcaag tccttcttga agaaataatg attgtggtct ccgtgactca
    22261 tgacaaaacc tgattcatct tcagcgataa tacgattagc atcaaatccg tatccatctt
    22321 cttcatgttt ctcatgtgaa gttcctggat tgattggaag agatggagaa ggtgttgaag
    22381 aatagcttaa ctgactcggt tgcatatttt ttccagccag atgtgcttta gctgctgcta
    22441 attcactagc agataaatcg cttttgggaa tgtagtgata gtgacctcca tgaggaacga
    22501 tataagcatt acccgtatct tcgataatat cagctggatt aaagacataa ccatcatttg
    22561 tcgtatatcg tccctgagac cttgctacag caacattaga gttaaccttc tcattatctt
    22621 tgacatgttc ttgtttttga cgattgattt catctttagt tcgaacatta tcagcatgag
    22681 ctgcatcttt caggtagaca taatattttc catcgacctt gatgatataa ccacccttga
    22741 cttcattgac aatatcagcg tctttaagtt gatagtttgg atccttcatc aagagttctt
    22801 cactaaagag ggcatcataa ggaactttcc cattatagta atgatagtga tcaccgtgtg
    22861 acgttacata gccctgatct gtaattttga ttacaatttg ctcagcctga attccttctt
    22921 tctggctaac ctggtctggt gtcaagtttt cacttttctg acttgactgg ctgccatcca
    22981 cataagagac acgattattg tccttatttt cctgcgaacg atgctggttt agtgcatagg
    23041 cacatagact caaggatacg ataacagctg atccagctgc tatatatttt ttactaaatt
    23101 tcataaatcc ctcatttcaa taaatgatga agttttttct caacttcttt tactttatta
    23161 aatagttttc taaaccggtt atttaaccat ttaattaacc agtaaatagt ttactattta
    23221 aaattacttt tgtcaagttt ctgttacgtt tttctaaaaa agagaagtaa cacgaaaggt
    23281 tacttctcca taaaatatgc tccattcatt ttactactgt atcggagccg gttgactttt
    23341 ttttaacaaa gccaagagac tatctacttc tgctgaaata gtgttattat ctttcgttcc
    23401 gagaagaaga ctacttttta gaccagtcaa tgtctccata gcattttgtc taatactagg
    23461 atctgttact ttttctagca aggcctccgc atctgctatc ttagcgttaa taacagaatt
    23521 ctctacttga ggaatttcag cctcatctgt ggtatcttca gcttcttcct ctgtctcttc
    23581 cgtatcagtg cttggtttat aaagattatc tgctgaagga tttaaaccag cgtgattctc
    23641 tttttcatca gattcagggt gagttggctc acttacttca tcatgttcct tatcttcatc
    23701 aggtttactg tcttggtctg ccttattttt acgaacatgg tc
//
LOCUS       DAVLIK010000033        20510 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLIK010000033 DAVLIK010000000
VERSION     DAVLIK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.033"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..809)
                     /gene="folK"
                     /locus_tag="VXE87_001415"
     CDS             complement(<1..809)
                     /gene="folK"
                     /locus_tag="VXE87_001415"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0842944.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALK"
     gene            complement(852..1406)
                     /gene="folE"
                     /locus_tag="VXE87_001416"
     CDS             complement(852..1406)
                     /gene="folE"
                     /locus_tag="VXE87_001416"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0842945.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(1387..2709)
                     /locus_tag="VXE87_001417"
     CDS             complement(1387..2709)
                     /locus_tag="VXE87_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0842946.1"
                     /translation="MKEFENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEVRLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDENVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(2711..3688)
                     /gene="folP"
                     /locus_tag="VXE87_001418"
     CDS             complement(2711..3688)
                     /gene="folP"
                     /locus_tag="VXE87_001418"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0842947.1"
                     /translation="MVKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGRSSYVEIEEEIQRVVPVIKAIRKESNVLISID
                     TWKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVIARPQHPSSL
                     IFPHFGFGQAFTEKELADFETLPIEDLMETFFDRALARAEEAGIAQENILLDPGIGFG
                     LTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTA
                     SAHVTSIAVRQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(3783..4490)
                     /locus_tag="VXE87_001419"
     CDS             complement(3783..4490)
                     /locus_tag="VXE87_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0842948.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(4543..5961)
                     /locus_tag="VXE87_001420"
     CDS             complement(4543..5961)
                     /locus_tag="VXE87_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0842949.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            6151..6963
                     /locus_tag="VXE87_001421"
     CDS             6151..6963
                     /locus_tag="VXE87_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0842950.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7302..8321
                     /gene="adhP"
                     /locus_tag="VXE87_001422"
     CDS             7302..8321
                     /gene="adhP"
                     /locus_tag="VXE87_001422"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0842951.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            8555..9544
                     /gene="manX"
                     /locus_tag="VXE87_001423"
     CDS             8555..9544
                     /gene="manX"
                     /locus_tag="VXE87_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0842952.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            9572..10375
                     /locus_tag="VXE87_001424"
     CDS             9572..10375
                     /locus_tag="VXE87_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0842953.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            10399..11310
                     /locus_tag="VXE87_001425"
     CDS             10399..11310
                     /locus_tag="VXE87_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0842954.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(11366..12700)
                     /gene="pepC"
                     /locus_tag="VXE87_001426"
     CDS             complement(11366..12700)
                     /gene="pepC"
                     /locus_tag="VXE87_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0842955.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(12812..13534)
                     /locus_tag="VXE87_001427"
     CDS             complement(12812..13534)
                     /locus_tag="VXE87_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0842956.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEIFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVEIFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILLASIA"
     gene            complement(13757..13987)
                     /locus_tag="VXE87_001428"
     CDS             complement(13757..13987)
                     /locus_tag="VXE87_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0842957.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(13997..15238)
                     /locus_tag="VXE87_001429"
     CDS             complement(13997..15238)
                     /locus_tag="VXE87_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0842958.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(15260..15412)
                     /locus_tag="VXE87_001430"
     CDS             complement(15260..15412)
                     /locus_tag="VXE87_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842959.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(15433..15711)
                     /locus_tag="VXE87_001431"
     CDS             complement(15433..15711)
                     /locus_tag="VXE87_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0842960.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(15704..15967)
                     /locus_tag="VXE87_001432"
     CDS             complement(15704..15967)
                     /locus_tag="VXE87_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0842961.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(16069..20460)
                     /locus_tag="VXE87_001433"
     CDS             complement(16069..20460)
                     /locus_tag="VXE87_001433"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0842962.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFETKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFINKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
BASE COUNT         5870 a         4837 c         3954 g         5849 t
ORIGIN      
        1 tttttcaaag catcatacaa gttgcggatc ggttgtttta atatcggatg gataaaatga
       61 ggcgcaattt cctgtaagga ctcaaggaca aaaaggcgtt ccgctatgta aggatgaggc
      121 aatatgaggt cgtctgtata aaggatctgg tcctccacaa agagcaagtc caaatcaatc
      181 aaacgaggtc cccaatgcac ttctctcacc cgtcccagct ctgactcaat ggctaacaag
      241 gtttctaaca agtcttgtgc tggtagccag gtttccacct caaccacttg attggcaaag
      301 ctatcctgct ccactccacc ccaaggctcc gtcgctaaga cactggactc tttgagaata
      361 tggatgccac gagctcgcag tttgtcaatg gcttgcttca agtttgcttg tttatctccc
      421 atattgcttc ctagggcgat aaaggctcgt tgcttgcggc gatgaatggt taccgagcaa
      481 gtatctagtg acaaatgcac cggtgcccaa ggttttttca gttccaactt catttcttgg
      541 acaagaggat aagactcaaa ggtacgttcc accagtttat aggctaccgt ttcaatcaaa
      601 tcttcactcg tttcctgaaa ccaagtcgtc cactgctgac acaattctcc gtaatggaca
      661 gaggctgtta aatccaagtc tgtagctgcc ttggtcatat cataggatag gatggctgaa
      721 acgacaaatt tctgccccaa ttctttctca ctaggaaaaa gaccatgata ggcaaacatt
      781 tccaaatcct taatctgcag ttgatccata atgattcctt tctagaaaaa tccgcttgaa
      841 gcggattctt tttatagccc cattaaacga taagcttggt cacggagatc cttatctgtt
      901 tcaaatagac cacgagctac tgtcgtcaag gttgcagtgc ctggttttct aacaccacgc
      961 atactcatac acatatgttc cgcctcaatg acaacaaagg ctcctttagc acctagatag
     1021 tccatcaagg catcggccac ttcgatattc aaacgttctt gaatttgtgg ttttttcgaa
     1081 taaacttcaa ccgtacgggc tagcttagac aagcctgcca cacgaccatc tggaatgtag
     1141 gcaatgtgcg ctctaccata aaatggcaag aagtggtgtt cacacatggt atggaaaaag
     1201 atatcctttt ctaccaccat attatcgtca ataatttcaa aggattttga caaatgttcc
     1261 tctgctgttt gaccaagacc tgaaaaaatc tcttgataca tacgggctac acgagcaggt
     1321 gtttcctgca agccctcgcg attagcgttc tctcctacag cctcgataat catttttaca
     1381 gctgcttcaa tcttttgtgt atccattctc gttcttcctc tccatcagat aggccctcac
     1441 ttggctcaag aaatacaagg aacctgtgac aatcctaact gtttgtttct cttctttttt
     1501 atctgtcaaa ttctgctcta gaaaatcatg ccaatcttgg tagctgagat ttctagactt
     1561 agctgcctct ttcagcacgt tttcatccgt cgcccgacta tccgcaaaat gtgttagagt
     1621 aagctcggta tctggcatgg ctcccagcaa gtccaacata tcctccaagg ccttggtttt
     1681 gatacaagtg aagaggattt ccttatgata atccgcaaaa cgttcttgca aggttaccaa
     1741 caaggccttg atagcatggg gattgtgggc tccatccaaa atcatcaagg gatctcttga
     1801 cacgatttcc aaacgccctg gccaacttgt ttcttccaag gcttgaccaa gaaaatcatt
     1861 gcttgctagc tctcgaccat cttcttgaca aaaagtatca agtaaagcta tggccatccc
     1921 agcattctct atttggtaca aaccaagcag gctagtctgg aagcgacctt gtctgacagc
     1981 acttgtatag tcaaagactt cccctgtcac cacactttct tgatgacgaa cctgataatc
     2041 tgtcccgtag gcaagtctcg gcgcatcttt cccttccgca atgcggtcaa tcacagccaa
     2101 ggcttctgga gcaatacgcc ctgttaccaa gggcatccct tgtttgataa tacctgcctt
     2161 ctgctctgct atggcctcca aggtgtcacc aagtagggcc acatgatcca agccaatagt
     2221 tgtaattcct gtcaaaatgg gctgacagac attggtacta tccaaaagtc cacccatgcc
     2281 aacttccatg atagccacat ctacttgctc tgaggcaaag tagtcatagg ctagggctgt
     2341 gataatctca aactcggttg tgccctgtaa attggcgacc gcttctccct ccagcaaaga
     2401 ctgatagtct gccatgagag cttctagcct cacttctgag atcgattccc cattgatgct
     2461 aatctggtct gtgtaatgaa tgagataggg cgagctaaac acgccaactc tcagccctag
     2521 cttttctagc atctttttca aaaaagcaat agtcgagccc ttgccgttag ttcctccgat
     2581 atggaggacc ttgagtttga gatggggatt gccacgcaaa gctaacagtt ccaccattcg
     2641 ttccaagcca aaatgcggtt gatccgtccg gtagttagca atccactgat tgttttcaaa
     2701 ttctttcatc ttatttatat tgttttaaat ctaaattttc cgcttcatca gccagacgaa
     2761 tagcggaggc aatttcaact gccatcctgt gactagctac atcatgcacg cgcaccactt
     2821 ccacaccctg tctcacagcg atactggtta catgagccga agccgtatct cgattgcgga
     2881 aaccaagttc tgtctcagga ttgacttcaa aaccattttc ttcaagaata ttgatgacaa
     2941 accgcttgcg cgacactccg agaaagattg gatagccttt ctgatgtagt ttatccagat
     3001 cccgtaaaag aagcagattt tctttcttgg tcaaaccaaa gccaattcct ggatccaaca
     3061 agatattttc ttgtgcaata ccagcttcct ctgctctcgc taaggctctg tcaaagaaag
     3121 tctccatcaa gtcttctatt ggcaatgttt caaagtcagc taactctttt tctgtaaaag
     3181 cttgaccaaa accaaaatga ggaaagatga gcgagctagg gtgctgaggt cgtgctatga
     3241 ctggattaaa cataatgact actttcgctc cagccttagc aaccacatgg gccatttttt
     3301 catcacccat gagaccagtg atatcattga ctagattggc accagcagcc aaagcagcct
     3361 ctgctacctg actcttccaa gtatcaatag agatgaggac attactttcc ttgcgaatag
     3421 ctttgattac tggaacaaca cgctggattt cctcttctat ctcaacatag ctgcttcttc
     3481 ccggccgagt cgattctccg ccgatatcta gcatactagc cccttctgct atcaatttac
     3541 gagcctgctg gagtgcttgc tcaagagcaa aaaattgacc accgtccgaa aaggagtctg
     3601 gggttacatt gataattccg caaatagctg tctttgcatg attggcttta cttgacatat
     3661 cggtcactcc ctcaaggctt ttcaccatat tatttctcta ttttaccata aaaagaaaaa
     3721 gatggacaca attgcattca tctttcccta gtagaaagag gtcggttcct acataaaaac
     3781 ttttaaacag aaattcctaa tgtccgactc ataatcacca caagagccaa caaacagaaa
     3841 gcaatcccat taacaatcat gtgaagcaag atcgacattt ccaaacgttg ggtcttgtag
     3901 gccgtccaag atagaactgt cgacatacct ccataaatca ataaagaagg taaattactt
     3961 ggttgatgca ataaagcaaa cacaatcgta ccgactacaa atcccaagtt ctccttgcct
     4021 cggaaaatct ttttaggaac aatcccacgg cacaagattt cctcacaaat cggagcaagc
     4081 aaggctagca agaagaaact ggaaatcaac gaactatttt gaaccatatc gttaatctga
     4141 gactggttag ctgttgtcgt ctcatttgac agttgcaaca agatagaacc aagtatattt
     4201 gacccgacaa taactaaata actcaatccc aaacgtgcca aatctttagc tctaaaaaaa
     4261 gaaaaattaa aactagctaa cttggtttta cgagctccaa taataaatag caccagaacc
     4321 acaatagaaa taccagtaac tatcagccct gactgtagca gggctacttc ttttaaagtc
     4381 aaaatagagg taaccactag gggaacctga tataaaagga cggcaagtaa aaagaccaaa
     4441 atccagcctg cacgattcaa caattctttc cacatatttt tctctttcat cacctatctc
     4501 ctttgtatta aaaaaggggg gaaatccccc tgggtcattc tattataagg ccatgctgat
     4561 gtagttaagg ataaacaagg catccaaaat ccaaatcatg gcatgaacat ctttaacttg
     4621 acctttgaca agcttagtca aagtgtaagt caagaaacca actgcaatcc cttgagtgat
     4681 agagtagctg aatcccataa agatagatgt gaagaaggca ggaactgctt cagacatatc
     4741 atcccaatgg atatttttca agctaccaag catcataatt ccaacgataa tcaagattgg
     4801 agctgtagcc gctgttggta cgatcgctag aagtgggcta aagaagcttg aaatcgcaaa
     4861 acagatagct acaaccaagg ctgtcaaacc agtacgtcca cctgcaccga taccagcagc
     4921 agactcaaca taagtcgtta cgtttgaagt acctgcaatg gcaccgactg tcgttccaat
     4981 caaatcagag taaagagcct tatccaattt ggctgattgg tgattttcac catttgtcgc
     5041 tacaatacca actttttcac ctgtaccgat caaggtacca attgtgtcaa aaatatctgt
     5101 caatgagaag gcaagaatgg ccatcagagt ttcaggcaag cgagctgtat ctgaaaccaa
     5161 agctcccaaa ccttctgaac caagagctgc accaaagatt gtcttcaaat cttcaaaagc
     5221 tgcaccaaca tggttattag caaaatcgat actagacaaa tcaaccaaac caactgcaat
     5281 agcaagaaca gttgttgtca agatagagag aataattccc cctttaatcc ctttgatgac
     5341 aaagaagata gtaatggcaa gtcctgcaag agccactaaa acagctggat tattaaagct
     5401 gaccaatcct ggaactgctg aagagtttgc tgcaatcgtt gcttgagctt tgtcagcccc
     5461 ttctcctaca acagtatagt tgcctggatc aatcgtgaat ttcaaaagtc cagcattctt
     5521 aatccctaca taggcaagga agacaccgat accagctgaa atagctgagc gaagagcatt
     5581 gggaatcgat tcaatgatca ttttacgaac atttgtcaag gtaataatca atgaaataat
     5641 cccacagatg aagaccatag ctagggcttc ttgccaagaa taaccaagcc cgaatacaac
     5701 tgtaaaggta aagaaggcat tgagtcccat acctggcgct tgggcataag gtaagttagc
     5761 ataaaaagcc atcatcaagg tacccgctac tgcaccaata atcgtcgcta ggaagacgcc
     5821 ctgagcaggc attcctgttt gtgaaagtat ttgtgggttt acaaagagaa tatagctcat
     5881 tgcaaagaaa gttgttaaac cagcgagaac ctctgtacga acgtctgtac cgttctcttt
     5941 tagtttaaat aatttgtcca tcatcaatct ccttttaatt tttacgaaca ataatagaat
     6001 tatatcattt atcattcact ttttcaatgt ctttgtttga tttgtttaag aaattaatcc
     6061 aatttcattt tttgtttgga atctgctttt ctgcctgctt tctgttataa tagaagacat
     6121 cttatctgaa aacacactag aaaggtccat atgacgaaaa aaattattgc agttgacctg
     6181 gatggaaccc tgctcaactc agacagtcaa atttctgact ttaccaaaaa aaccatcaaa
     6241 aaagttgctg aaaaaggcca tcaggttatt attacgacag gtcgccctta ccgtatgtca
     6301 aaagattttt accgtgaact gggcttagac actcctatga ttaacttcaa cggatccctt
     6361 actcatttac cagaccaagt ttgggatttt gaaaagtgtt tgactgtaga caaaaaatat
     6421 ctgctagata tggttcaacg ttcagaggac attcaagccg attttatcgc tggagaatat
     6481 cgtaaaaaat tctacattac aaatcccaat gaagaaattg ccaatcccaa actatttggt
     6541 gtagaagctt tccagcctga agatcaattc cagcctgaat tggtgaccaa ggaccctaac
     6601 tgtatcctct tgcagaccag agccagtgac aaatatgcct tggcaaaaga catgaacgcc
     6661 ttctaccagc atcaactttc tatcaatacc tggggaggtc cgctcaatat ccttgaatgt
     6721 accccaaaag gtgtcaacaa ggcctttgct ttggactact tgctcaagat aatgaatcgt
     6781 gacaaaaaag atttgattgc ctttggagat gaacacaatg ataccgaaat gctcgctttt
     6841 gctgggaaag gttatgccat gaaaaatgcc aatccagagc tactccctta tgcagatgag
     6901 caaatttccc ttaccaacga ccaagatggg gttgccaaaa ccctacaaga cttattctta
     6961 tagcctacac tgatactcaa tgagaatcaa agagcaaact aggaagctag ccgtaggttg
     7021 ctcaaagcac tgctttgagg ttgtagatga agctgacgtg gtttgaagag attttcgaag
     7081 agtatgacca gcttgcaagc tggtctttgt gctcttttca cagtctcatc aaccagttaa
     7141 tcgattgttc tactttttgt ctccaaaacc ttggaaaagg ctttcttttg tgatatactt
     7201 cacatataaa tacaagagag ctcgtcacac tcgactctgt tgacaaaaaa tcaatccagt
     7261 cccgttgtcc ctgttctcgg tcaatatcaa ggaggatagc tatgaaagct gttgttgtaa
     7321 atccagaaag cactggtgtt gctattgaag aaaaagtact ccgtccactt gaaactgggg
     7381 aagcacttgt agaagttgaa tactgtggcg tttgccacac cgacctccac gttgctcatg
     7441 gtgactttgg tcaagtccca ggacgtgttc ttgggcacga aggtatcggt atcgttaaag
     7501 agattgctcc agatgtgaaa agccttaaag tcggtgaccg cgtcagcgtt gcttggttct
     7561 ttgaaggatg tggcacttgc gaatactgta caactggtcg cgaaaccctt tgccgtacag
     7621 tgaaaaatgc tggctactca gtagacggtg gtatggctga acaatgtatc gtaactgctg
     7681 actatgctgt caaagttcct gacggacttg atccagccca agcttcttct atcacatgtg
     7741 ctggagtaac aacctataaa gctatcaaag aagcaaaagt tgaaccaggc caatgggttg
     7801 ttctttacgg tgctggtgga cttggtaacc tcgctgttca atacgctaaa aaagtattca
     7861 atgctcatgt tatcgcagtc gatatcaaca atgacaaact tgcccttgca aaagaagtag
     7921 gcgctgacat tgtgattaac ggcctcgaag ttgaagatgt agctggactc atcaaagaaa
     7981 aaactgatgg aggagctcat tcagctgtcg taactgctgt gtctaaagtt gccttcaacc
     8041 aggctgttga ctccgttcgt gctggtggtc gcgtcgtcgc tgttggtctt ccttctgaaa
     8101 tgatggaact cagcatcgtt aaaacagtcc tcgatggaat ccaagtcatc ggttctcttg
     8161 tcggaactcg taaagactta gaagaagcct tccaatttgg tgcagaaggt ctggtagccc
     8221 cagttgttca aaaacgtcca gtagaagatg ctgttgccat tttcgacgaa atggaaaaag
     8281 gtcaaatcca aggacgtatg gtactcgact tcacccacta atctaataga aacctatttt
     8341 aaaagttgga agcttcttcc aactttttta tattaaattt ttaaataaga attcaagatt
     8401 actcctcaaa aactcaacat atcaacatac aaaaataaaa tttttttaat tttttatgat
     8461 aaatagttgc tttttttatg aaaacggttt atacttaaac agtcttaaag ttttcttaaa
     8521 tgaaaactaa aacaaaaaag gaggaatgac aataatgagt atcggaatca ttattgcgag
     8581 ccacggcgaa tttgctgcgg gtattcatca gtcaggatct atgatctttg gtgaacaaga
     8641 aaaggttcaa gttgtgacct ttatgccaaa tgaaggtcct gatgatctat acgctaagtt
     8701 taataacgct gttgctgcat ttgacgcaga agatgaggtt ctagttttgg ctgacctttg
     8761 gagtggttct ccatttaacc aagctagtcg cgtgatggga gaaaatcctg agcgtaagtt
     8821 tgccatcatc acaggactta acttaccgat gttgattcaa gcctacacag agcgcctcat
     8881 ggacgctgct gcaggtgtag aaaaagtcgc tgctaatatc attaaagaag ccaaagatgg
     8941 catcaaagct cttccagaag agctaaatcc agttgaagag gttgcaagcg ctgcagctgc
     9001 tccagttgcc caaactgcta tcccagaagg aactgttatc ggagacggta aattgaaaat
     9061 caatcttgcc cgtcttgaca cacgtctact tcacggtcag gttgcaactg cttggactcc
     9121 agattcaaaa gcaaatcgta tcatcgttgc ttcagataac gtggctaaag acgaccttcg
     9181 taaagaattg attaaacaag cagctccagg taatgtcaag gctaacgtgg ttccaattca
     9241 aaaactgatt gagatttcaa aagacccacg ttttggagaa acacatgccc ttatcttgtt
     9301 tgaaacacct caagatgccc ttcgtgccat cgaaggcggc gtgccaatca agactcttaa
     9361 cgttggttct atggctcact caacaggtaa aacattggtc aataccgttt tgtctatgga
     9421 caaagaagat gttgctacat ttgaaaaaat gcgtgacttg ggtgttgaat ttgatgtccg
     9481 taaagtacca aatgattcta aaaaagattt gtttgacttg attaacaaag ccaatgtcaa
     9541 ataagccatt atttatgaaa ggattttaaa catgtctatt atttctatgg ttttagtagt
     9601 cgttgtagcc ttctttgcag gtcttgaagg catcctcgac cagttccaat ttcaccaacc
     9661 acttgtagcc tgtaccctta ttgggcttgt aacaggtcac ttggaagcag ggattatcct
     9721 cggtggatcg cttcaaatga ttgcccttgg ttggtcaaat atcggtgctg ctatcgctcc
     9781 tgatgctgca cttgcttctg tcgctgctgc cattatcatg gttcttggtg gtgactttac
     9841 caagactggt atcggtgttg cccaagcggt tgctatccct cttgccgtag ctggactttt
     9901 cttgacaatg attgttcgta caatttcagt tggtttggtt cacactgcag atgctgccgc
     9961 taaaaaaggt gacttcggcg ctgtggagcg tgcgcatttc attgcgctac tcttccaagg
    10021 acttcgtatc gcgcttcctg cagctcttct ccttatggta ccaactgaaa ctgtacaaag
    10081 tatccttagt gccatgccag actggctcaa agatggtatg gctatcggtg gtggtatggt
    10141 cgttgccgtt ggttacgcta tggttatcaa catgatggca actcgtgaag tatggccatt
    10201 cttcgctctt ggtttcgttc tcgctgctgt gtcagatatt actctaatcg gattcggtgc
    10261 tatcggtgtt gctatcgctc ttatctacct tcacctttct aaaactggtg gaaatggtgg
    10321 cggaggagcc gcaacttcta acgacccaat cggcgacatc ctagaagact actaagataa
    10381 gaaaggactg aaaacatcat gactgaaaaa cttcaattaa ctaaatcaga tcgtaaaaaa
    10441 gtttggtggc gttcaacctt cttacaaggg tcttggaact ttgaacggat gcaaaacttg
    10501 ggctgggctt atacactcat tccagctatc aaaaaactct atactaaaaa agaagatcaa
    10561 atcgctgctc ttgagcgtca ccttgagttc ttcaacactc atccatacgt agctgctcca
    10621 gtcatggggg ttactcttgc gcttgaagaa gaacgtgcta acggtgtgga aatcgatgac
    10681 gctgctatcc aaggggttaa aatcggtatg atgggacctc ttgctggtat cggtgaccca
    10741 gtattctggt ttacagtgcg cccaatcctt ggatctctcg gtgcttcact tgcccttact
    10801 ggcaatatct tgggtccact cctcttcttt gttgcatgga acttgattcg tatgtcattc
    10861 ttgtggtatg ttcaagagat tggatacaag gctggatcag aaatcactaa agatatgtct
    10921 ggtggtatcc ttcaagatat cactaaagga gcttctatcc ttgggatgtt cattcttgct
    10981 gtccttgttc aacgctgggt aaatattaaa tttgctttcg atgtttctaa agttcaacta
    11041 gatgaaaagg cttatatcca ttgggataaa ttgccagaag ggtctaaagg tatccaagaa
    11101 gcattcgcac aagtaggaca aggattgtct caaactcctg aaaaagttac tactttccaa
    11161 caaaacttgg atatgttgat tcctggatta tcaggactac tccttacttt actttgcatg
    11221 tacttactta agaaaaaagt atctccaatc actattatcc ttgccctctt cgcagtgggt
    11281 attgtggcac atgttcttca catcatgtaa tcaagcaact aaaaaggaac caggttctaa
    11341 aatctgattc cttttttcta tgcttttatt cagccaaggc tcccattgga tcccatggtg
    11401 caagtacaat tggttctgct ccataggcag cttgttcttc tgctgtcagc aattccttac
    11461 gaacaacgat ttggtatgtg tattcgtcca tccaagcgtc tgaggcaaca aagtaaccat
    11521 ctgtaccgac cttgtctccc catgagtttt caaccttcca cttggttgat ttaccatttt
    11581 cgtccaagtc aacacctgtc aagaccatgg cgtgggtcat caagctttcg ctatagtcca
    11641 aacgtccagc cttgtcttga gtaagtttaa tgtccatgct tgattcaaag tcataaacat
    11701 ctgtcgcaag gatgccagcc ttacggttac tgagctggcc gacatcagaa ccaaaccaaa
    11761 cagtctcacc tgcttgcatt tgggcaatcg ccaattcttt caagcgctcc attggaacgt
    11821 tgatgtaacg aactgcacgg ctaccaacca cattccccaa catctcaact gtgtaagatt
    11881 ttccgtaagg tttatcagca gttggagcat tgataacaga aacgtagtct tctaaaggaa
    11941 gattgacata tttcttgtaa aactcttgtg gtgtgattcc tttttcactt ttgtagttgt
    12001 tatctttatc gcgataagca aagtcaaact tgcgtggtgg aagtcctaat gacatagcaa
    12061 gaaagttaaa gatttcttgc aagaggtctt ctttcttagc ttgaacagtc gcttgatctg
    12121 caccagaaac aagcaagtca cgcaagattt gagcatcttg acgaagcaat ttattaagga
    12181 tcgcatttag ctcacgactg ctgctagatg aaacagactc aggataaact gacttaggca
    12241 cgacaccgta tttttcaaag agggaaacga ccatatccca ttgaccacca tcttgttgag
    12301 gtgtttgaag taagaagcta accttgcggc tagtcaattc ttggtctgaa gtcgcaatga
    12361 cttgctccaa gaaccagttt gatttctcat acttatccca gaagaaagtg tgggcttgtg
    12421 acaactcaaa gttctccaat ttgtattgcg agatgagttt gtggcggaag gtgttgagag
    12481 ccgcaaacat ccagcaacga ccagacgctt tctggttagt gaccttgtcc ttggttaaat
    12541 ccaatgagaa aacaggtgtg ttgtctacat ggctttggcg acgttccaga gctgcaaaaa
    12601 ttccgttgtg gctagcagca ttttcaatcg cttggtattt tacatttgct tcatagttgg
    12661 caaatagttt atcagtaaat gattcttgaa tcgcgttcat agattcctcc ttttattcta
    12721 cagtctatta taactctttt cacaaaggaa gcaactaaaa aacataaaag gtaaggacat
    12781 tctccctcac ctttttcgaa tataaatcaa attaagcaat actagcaagg agaatttcta
    12841 attcttcctt ggtcaagcga cgccattccc ctcgttccag gttctcatct aatactaaag
    12901 ttcccatagt caatcgttgc aagtccacca cttccttgcc acagtagccc accatacgct
    12961 tgatctgatg aaacttccct tctgcaatgg tcacacggat ttggctttga ttcttttctg
    13021 tatctatgga tacaagctcc agtatagcgg gttgacaggt aaagtctttg agaggaatac
    13081 cctcagcaaa tatctccaca tcttcttggg tcatgattcc cttgacttgt gccagataag
    13141 tcttgtccac atgacgcttg ggcgaaagaa gaacatgagc cagctgacca tcattggtca
    13201 agagcaaaag accatgcgtg tcaatatcca agcgtcctac tgggaaaatt tccttactcc
    13261 gcgccaagtc atccaacaag tccagaacgg ttctgtgctt gggatcctca gtcgctgata
    13321 taactccttt gggcttgttc atcatgtagt agacaaactc ttcatactcc aacacttgcc
    13381 catcaaagcg aatctcatct attttttcat caatctgcaa tttagctgat ttttcttttt
    13441 taccatttac agtcacgcgc ccagccttga gcaagttttt gacctcagtc cgacttccca
    13501 ccgcacaggc aactaaaaat ttatctaatc tcatagaact attatatcat atcaaaagga
    13561 ggctggtaca atgaccaacc tccttttcgt ttcatactct tcaaaaatct cttcaaaccg
    13621 cgtcaacgtc gccttgccgt atatatgtta ctgacttcgt cagttctatc tgcaacctca
    13681 aagcagtgct ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    13741 tatcagattt aagaaattaa cttcctcgtc tccaaaaaat agctaagaca atcatggcac
    13801 ctaaaacagc tgggataata gctgttcctg ataaaactgg cccccaagtt ccaaagagca
    13861 agtgacctag aaaggctccg atccaaccga gaaacatttt tccaaaacat cccattcgct
    13921 ctccacgatt ggtcatagca cctgctaaaa atcccactag gagaccaacg aacatacttc
    13981 ctaacatatt atctccttaa tttgcccaat tcccattacg gaaaagaggt actcgcgttc
    14041 catcctcacg aataccatcg atatccattt ggttagaacc aatcataaag tctacgtgaa
    14101 catctgaacg gttaagccct gcagcttcaa gctcctcttc gctcatctcc gctccatcaa
    14161 caacgctagt cgcataggct gcaccgatag ccaagtggtt tgacgcattt tcatcgaaaa
    14221 gggtgttaaa gaaggtaatg cctgactgag aaattggact tggatctggt accaaggcac
    14281 attcacccaa ggcacgcgca cccgcatttt caaagacaag gtctttcata acctgatcac
    14341 ccttctcagc agtgatatct acgatttgtc catccttaaa ggtcacctta atgccttcaa
    14401 tgatatttcc gttgtagcta agcggttttg tagaagtgac ataaccatct gcacgacgga
    14461 agtcaggcgc tgtgaagacc tcttctgtcg gcatatttgg caagaattct tcgccctgtg
    14521 cattgacagc accagctgat tcccaaacgt ggttctttgg caaaccaagt gttaaatctg
    14581 ttcctggcgc tgtgtagtga agggctgaaa attgctcctt attaagcata tcggccttgc
    14641 tcttgagaat ggctgcatgt tcctcccaag ccttaacagg atctgcttcg tagacacggc
    14701 aagttttgaa aatttggtcc caaaggaaat caactgcttc ttcgtcgctc gcagcatttg
    14761 ggaagacttt cttagcccac tcaagtcctg ctgcagctgc tacagtccag ctaactttgt
    14821 tagattgagt tgcgattcgc attggcttca tggcaagtcc catagcttta gcagaagctg
    14881 aaagcttgtc agcgtccact ccgttcaagg cacctggatc agatgaacga actccaagac
    14941 ggctagcctt gttctccaag agatagttca tctcagcaat cttgtattct ggcacattgt
    15001 ccaaacgctc catcggggca tggaggaatt tctcacggtt aatcacatca tctgtccact
    15061 gaacgatgac ctcatgcgca cccaaggcat aagcttcttt cacgattaga tgtgccaatt
    15121 cacgttgctc cacatcaata gagagagcca aagtgtgacc aggttgcacg ttaattccgt
    15181 tcgcaaccaa caatttcgca tatttttcta gattttcttt aaaatttggt aaaaccatcc
    15241 tgttttctct tttctatttt tatttttctt tcaaagcaga aaagattcct gctaaagcaa
    15301 tagcacctga caagagtgct gtcgatagaa gaattgtacg atcagcaagt tctaattgat
    15361 attcaaatac cttcttagcc ggcttatctt ccgcaaatat tcttagtttc atgagaaccc
    15421 ccttaaaata gattaaaata aatcactgtg actgcctgtc ctcagcaaat ttaaaatcaa
    15481 ttccgactta tctactttat aaaccaaaag ccaatctggc tgggtatggc attcacgaac
    15541 tccttgaaaa tgcttggatg ccgtcaatga atgatcacga tatctggcag gatgttcttt
    15601 ttcttgaacc agaaaattca aaacttcttc taataattct gccttcaaac cacgcttcat
    15661 agccaactta aaatcttttt taaactgttt atgataacga atcttaagca cgtaagtcct
    15721 ccatcaaatc tgagactgat tcaaaagact ggctcatatt acgattttgg tctaaatccg
    15781 ttaacacttg gagcaacttc cgattttcgt ctagtctaac atcaaaaggt aatccctgat
    15841 attgaattgc ctgacgaagg aaaatattaa tagctgttgt catatccatt cccagattac
    15901 taaacacctg ttgggcctgc tccttaacct cactatccag acggatgctc atactcatct
    15961 ttgacatact ctcaccctct ttccatagac tattttaaca aaaaagaaag ctaatgtaaa
    16021 tctattggat atacgttagc ctcttctaat agattattaa gcaatttttt aaaacaactc
    16081 atcaaacaaa ctcaactggt tatcctctgg catatttcca agaataccca tctcatccat
    16141 cttttcaacc aaggttgatg agagtccacc acgcttgcgt agttctgttt tagagaggaa
    16201 ttctccctct tcacgcgccc gcaccagttg cttggcaacg ttctctccca gaccatccat
    16261 tgctacaaat ggtgggataa gggtatcccc gtcgatgagg aactctgtcg cctgactacg
    16321 gtagagatct aatttgccaa acttgaaacc tcgttcccac atctcattga caatctcaag
    16381 agttgtatag agatcgattt ccacattaga ggcttcattg ttcttccgtt tttcagagat
    16441 ttcttccatt ctgcgcttga tggcctccaa gcccgcaccc atggtcttga tatcaaaagc
    16501 cttagcacga atggagaagt aagcacagta gtaataaata ggatggtgaa ccttgaagta
    16561 agctacacgc aaggccatca taacgtaggc tgccgcatgg gccttaggga acatgtactt
    16621 aattttccca caggattcga tataccactc tggcacctta ttagccttca tggcttcgat
    16681 atagccattt ctctcctctt ctgaaatctt tagccacaaa cccttacgta cccgttccat
    16741 aatggtaaag gccatcttag gttccagacc cgcatgcatg aggtaaacca tgatgtcgtc
    16801 ccgacaaccg ataacagtcg ataggtccgc tattccttgc ttaatcagat cctgagcatt
    16861 ccccaaccaa acgtcagtac cgtgggacag accagacagc tgaagcaatt ccgcaaaggt
    16921 tgtcggatgg gtttcgtcta ccattccacg tacgaaattt gttccaaact ctggaatccc
    16981 caacataccc gtaggcgttc caatttgttc aggtgttacc cctagcacat cagtcccaga
    17041 aaagagtgcc atcacgcctt cgtcatccat aggaatttta ttagggtcaa taccagacaa
    17101 atcctgaagt tttcgaatca tggtcggatc atcatgtccc agtacatcga gtttgaggac
    17161 gttctcatcg atatcgtgga agttaaagtg agtggtctgc cattcagccg tgacatcatc
    17221 tgctggatac tggacaggcg taaaatcgta gacatccatg tagttcggaa taacaacgat
    17281 tccccccggg tgttggcctg ttgtccgctt gacacccgcc gctccttgag cgaggcgttc
    17341 tacttctgca tcacgataaa acttgccata atctcgctcg taacccttga caaatccata
    17401 ggcagtcttg gcagctaccg taccaaccgt tcccgcacgg aaggcatatt cttcaccaaa
    17461 gatatcacgc acatccaagt gggcgctagg ctgatcttct cccgagaagt tcaagtcaat
    17521 atcaggaacc ttatccccat caaaaccaag gaaggtctca aacggaatat cctgtccgtt
    17581 tttactgagt ttgtgaccac agtttggaca gtccttatgg ggcatatcaa atcctgaacc
    17641 gtacgaacca tctgtgataa actcactgta ctgacactga ccacagacat agtgaggaga
    17701 gagaggattg acctccgtaa tcccaatcat ggtcgcaacg aaactagatc cgacagaccc
    17761 acgagaacca accaaataac cccgttcatt agaacgttgc accagcatct gcgatgccag
    17821 ataaatcaca gcaaatccat tccccagtat ggatgttaat tctttttcaa tccgcaaatc
    17881 aacaatatct ggcagcggat ttccataaat ctcaaaagct ttcttatagg tcaactcagc
    17941 aactgtttct tcagccttgt tgatgaaagg cgtatacaag tcacccttaa cgacttcaac
    18001 gggttcaaat atttctgcca aggcattagt gttttcaata accagtttac gagccagttc
    18061 ctctcccaaa aaggcaaatt catccaacat ctcattagtc gttcgaaaat gagcctttgg
    18121 aagtggcgct ggttgggcat gttcaccatg accgatagtt cggttaatca tcgcaccctg
    18181 tcccaaacta cggacgataa tttcacgata aatctcttct tccggttcga tatagtgaac
    18241 atttcccgta gccagaacag gcttgccaag gcgatctcca acctctatca aactcttgat
    18301 aatggtctgg agttcctcca tatccttgac ctgctctttg gcaatcaagg gcgcatagat
    18361 agccggtggc atgacctcga taaagtcata atacttggcc acctcaaccg ccgcatccac
    18421 accttgagaa acgaccacgt caaaaacttc accctctgaa caggctgaac ctaaaatcaa
    18481 gccctctcga tgggcatcta gaaccgttct cggaatccgt ggcactcctt caaaatactt
    18541 ggtattagac aaggaaacca gcttaaagat attttttaga cctacctgat tcttgacata
    18601 gatggtcgca tgcttgatcc gagctttttt gtaagaatct ggactgatta gatcaatgtt
    18661 gagtctagct aaatcggtca caccatgttt ttctgctacc tctttgataa agatgaaaag
    18721 cagacgacca gtcgcttccg catcgtagtt ggccatgtgg tgatgttcca aggccacacc
    18781 aaaacgcttg gtcaaaggcc ccaaaccatg gcgtttatac tcaggataga ggtttctagc
    18841 aaactccagc gtatcaataa ctggctgact aatctttgga agaccatgac gctcataatt
    18901 agcattcata aagccaacgt caaaggcagc attgtgggca actaggaccg tatccttgca
    18961 aaattcttgg aattcttgca aaacttgttc tagtggtttg gcatttttga catgatcatc
    19021 tgtaattcca gttaactctg tagtaaaagc tgacaaggga tgcccaggat tgataaattc
    19081 atcaaattca gcaataacat tccccttgta catcttagag gccgcaacct gaatcaagtc
    19141 attatagata gctgaaagtc ccgtcgtttc cacgtcaaag accacgtagg ttgcttctga
    19201 taagtccatc tccacttcgt tatagacgat agggacacgg tcctccacga tattggcttc
    19261 tatcccatag atcagctgga ttcccgcttt cttagccgcc ttatagccat gtggaaagga
    19321 ctggacattc ccatggtctg tgatagcaac cgccttgtgt ccccacttag cagctgttgc
    19381 aacaatctct tcgacctctg gcaaagcatc catagtcgac atgttagtat gagcatgaaa
    19441 ctcaacccga cgctcacctt ctggcatcaa atccttccgc tcatagtgaa caacttcctg
    19501 cagatcctgt acgttcatag tcaaatcgcg tgtgaagtta ttcatctcca cattccctcg
    19561 aactcggagc caagaattct tcttgatgag gtcaaacttc tgggcctctt cctcgttttt
    19621 aacccacttt tgcatagaaa aacttgaagt atagtccgtc attttaaagt tgattaaaac
    19681 acgacctgtt ctagtcactt tttgctccac atcaaaaaca accccttcaa ataccagacg
    19741 attttcctct gtcgtcactt cgatcatagg agtaatctcc gccttatcca gcttgggttt
    19801 agctgcagct tttttcgctt gaaaatcaaa gactggtttc tcttccgctg gaggaggtgc
    19861 catctgctcc agttgttcca tagcacggag cgcttcctca ttggcagctt gaacaatctg
    19921 ctcattttca gcatgaaagg cctcttcctg ctcttgggtc aggacatcat tcttctcgac
    19981 ttgacagtta aaagttggaa aaccaaactt ttcaagttgt ttggctaaat taggaagatg
    20041 attcttctta aaatgttcct tatcaatcgc ttcagatcct tcaataaata gctgattacc
    20101 ctcagcacga acttgcaaat tttgataaag ggacttaaaa ccttgactag cacatggacc
    20161 ttcagagaaa gcctccctat agtaggactg caagagctga tttgaaaatt cttgagaccg
    20221 agccttagtt tcaaaaacag ctttattgcc tgtcttagaa aattcttcgc tcaaaccttt
    20281 ctttaattct aaaaagattt caatcggtaa aatattagaa aatacgaaat gaaactccca
    20341 taccttacta attttatgaa ccacaactcg ctcaatattg gcctgtgcta aagcaggagc
    20401 ctgtctcatt tcagcaggca tccccaattg attcatcaaa atttcaaaac tatttgacat
    20461 tcattttcct cacattattc ttctactatt ttaccatatt tagaggtatt
//
LOCUS       DAVLIK010000034        19550 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLIK010000034 DAVLIK010000000
VERSION     DAVLIK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.034"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..769
                     /locus_tag="VXE87_001434"
                     /pseudo
     CDS             1..769
                     /locus_tag="VXE87_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(885..1688)
                     /locus_tag="VXE87_001435"
     CDS             complement(885..1688)
                     /locus_tag="VXE87_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0842963.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYENATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1965..2720)
                     /locus_tag="VXE87_001436"
     CDS             complement(1965..2720)
                     /locus_tag="VXE87_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV0842964.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2790..5441)
                     /locus_tag="VXE87_001437"
     CDS             complement(2790..5441)
                     /locus_tag="VXE87_001437"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0842965.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDARFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTINPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5434..6012)
                     /locus_tag="VXE87_001438"
     CDS             complement(5434..6012)
                     /locus_tag="VXE87_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0842966.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(6012..6572)
                     /locus_tag="VXE87_001439"
     CDS             complement(6012..6572)
                     /locus_tag="VXE87_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0842967.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEVI"
     gene            complement(6575..7138)
                     /locus_tag="VXE87_001440"
                     /pseudo
     CDS             complement(6575..7138)
                     /locus_tag="VXE87_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            complement(7422..7817)
                     /locus_tag="VXE87_001441"
     CDS             complement(7422..7817)
                     /locus_tag="VXE87_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0842968.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7913..8167)
                     /locus_tag="VXE87_001442"
     CDS             complement(7913..8167)
                     /locus_tag="VXE87_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0842969.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(8177..9511)
                     /locus_tag="VXE87_001443"
     CDS             complement(8177..9511)
                     /locus_tag="VXE87_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0842970.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEVFEAFAIEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9511..9744)
                     /locus_tag="VXE87_001444"
     CDS             complement(9511..9744)
                     /locus_tag="VXE87_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0842971.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(10159..10341)
                     /locus_tag="VXE87_001445"
     CDS             complement(10159..10341)
                     /locus_tag="VXE87_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842972.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(10343..11122)
                     /locus_tag="VXE87_001446"
     CDS             complement(10343..11122)
                     /locus_tag="VXE87_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0842973.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYLILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            complement(11401..11751)
                     /gene="rbfA"
                     /locus_tag="VXE87_001447"
     CDS             complement(11401..11751)
                     /gene="rbfA"
                     /locus_tag="VXE87_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0842974.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(12002..14794)
                     /gene="infB"
                     /locus_tag="VXE87_001448"
     CDS             complement(12002..14794)
                     /gene="infB"
                     /locus_tag="VXE87_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0842975.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(14811..15110)
                     /locus_tag="VXE87_001449"
     CDS             complement(14811..15110)
                     /locus_tag="VXE87_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0842976.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(15103..15396)
                     /locus_tag="VXE87_001450"
     CDS             complement(15103..15396)
                     /locus_tag="VXE87_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0842977.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(15418..16554)
                     /gene="nusA"
                     /locus_tag="VXE87_001451"
     CDS             complement(15418..16554)
                     /gene="nusA"
                     /locus_tag="VXE87_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0842978.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(16598..17077)
                     /gene="rimP"
                     /locus_tag="VXE87_001452"
     CDS             complement(16598..17077)
                     /gene="rimP"
                     /locus_tag="VXE87_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0842979.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(17203..17838)
                     /gene="trmB"
                     /locus_tag="VXE87_001453"
     CDS             complement(17203..17838)
                     /gene="trmB"
                     /locus_tag="VXE87_001453"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0842980.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(17835..18629)
                     /locus_tag="VXE87_001454"
     CDS             complement(17835..18629)
                     /locus_tag="VXE87_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0842981.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(18790..19401)
                     /locus_tag="VXE87_001455"
     CDS             complement(18790..19401)
                     /locus_tag="VXE87_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0842982.1"
                     /translation="MIWVDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
BASE COUNT         5481 a         4436 c         3654 g         5979 t
ORIGIN      
        1 gacctactac tatcacttga aacagctaga caaaacagat aaggaccaag agcttaaagc
       61 tgaaattcaa tccattttta tcgaacacaa gggaaattat ggttatcgtc ggatttattt
      121 agaactaaga aatcgtggtt atctggtaaa tcataaaaga gttcaaggct tgatgaaagt
      181 actcaattta caagctaaaa tgcgacagaa acgaaaataa aggagacgtt ggtaagaagg
      241 cagagaatct cattcaaggc caatttgaag gatctaaaac aatggaaaag tgctacacag
      301 atgtgacaga atttgccatt ccagcaagta ctcaaaagct ttacttatca ccagttttag
      361 atggctttaa cagcgaaatt atcgcctata atctttcaac ttcacccaac ttagaacaag
      421 tacaaacaat gttggaacag gcattcacag agaagcacta cgagaatacg attctccata
      481 gtgaccaagg ctggcaatac cgacacgatt cttatcatcg gttcctaaga gtaagggaat
      541 tcaagcatct atgtcacgca agggaaacag ccaagacaac ggtatgatgg agtccttctt
      601 tgggattctg aaatcggaaa tgttttatgg ctatgagaaa acatttaaat cacttaatca
      661 attggaacaa gctattgtag actatattga ttactacaac aataaacgaa ttaaggtaaa
      721 actaaaagga cttagccttg tgcaatacag aactaaatcc ttcggataaa ttatttgtct
      781 aactttttgg ggtcagtaca cctaaaactt tgatgatata cgttttcttg tgagaatatt
      841 tacttcattt ttgcctaaaa ttcaatgttt actcagtatt tggattatga aaaatcgagg
      901 tctaaatcta gatacatttt ttctgaagac aaatcatttt gaccaccgag caagagattt
      961 tcaaaaaaag ctgttaaaaa ctcagaacgt cgctgtaaaa tctttgcatt atctaatacc
     1021 aaggcatcac gaaaatattt ggaatgttgc tgaaatggtg tattatcaat atcaaaacca
     1081 aactcacgaa gatactgaat caaaaagacc gttactgtcc gagtgtttcc ttcgcgaaat
     1141 ggatgaatct gccagattcc tgaaataaaa tgctggattt gtttaaccac atccgcctga
     1201 gttagtgtcg catatgcaac ttgtttttcc tgattaaaat cataatctaa ggtcatttga
     1261 atcatggagt aatcagagta cacaacactt tcaccattca aaacaggttc attctttgtg
     1321 atattggtct gacgaaattg ccccaccgga atagagggtt caaatatatc ttgaaacaac
     1381 tccttatgaa tagcaagtaa ggtcgcagga ctaaagctaa agcctcttcg agacaatagt
     1441 tctacaatac gtagagaaac caagtctgcc tcttccgtac ttgcatcaat agtatggtga
     1501 taagccgttg cattctcata aacctgctca taagtcagtt ctccccggga ctgtttctca
     1561 gccaaagatt ccatatacgc tgatggcact agattgtcaa ctttctgcag accaaaacct
     1621 atccgccata aatcacgctt cgcttcataa gacaagtttg gattgtcaat gttgtaagtt
     1681 gattgcatag aaatatcctt tcaattgttt ttcttcatta ccagtaaatc acgaaattgg
     1741 ttggaaactg gcttaaacta taaaaagtcc tcacaatagg ttctatgata tatatatata
     1801 cttcatgtaa ataataaaag agttataatc agcactactg ataaattcaa taccgatttc
     1861 gccatcttaa aacttagtca aacgaatacc gttgatttcc agttcattaa gtcgttgacc
     1921 tgtcaagact tctcgttcct tcaactggaa aagttaaggg ggaactaata caaatcctct
     1981 acgcttctat attcaatgat ttcatttttg ataatattct ttttaaactc aaaatgtttt
     2041 aaaggattat cgattaacac taactttgga atatcatcta gatttgtgac caaggataaa
     2101 ataaaatccg attgaaactc cttgactttt tcaaattctt ttgcagttaa acgcacacgc
     2161 cccttagatt ttcggatacc ttttacttcg gcaaggtaag aatactcttg gacatctacc
     2221 tgaaagtcat atccatcacc ataaagacgg gcatcggtta actgtccacc ttggaatttt
     2281 tcttctttat caaaatgaag gataaaataa ttctcagcct ccattcccgt ttcctgtaga
     2341 cgtttgaatt tagttcgaac tattggtttt tcaacgatgg ttatgcctgt tttcttccct
     2401 tcactggcaa gtaacatttt aactatttca gcataactat gaacatcttc atttccaaac
     2461 atcatatcaa ttaaatcttt acgaaaacga taaacttcag ctttctgcca ccaacctttt
     2521 cgattattgt caaaataagg atcaaataaa tccattctat tttttacaac tccagttgtt
     2581 tcagcaattc ccagagaaac cacatagcga taaaactccg acttgctaga gcattgaaat
     2641 tcttttataa aaagcttgtc aaacttggca agaccgtagc caattaaatt taacaattca
     2701 taatgagggt gtttggacat cactttctcc atcaatagat attgatttca ttataccaaa
     2761 aaacacggct catcaccgtg tttctgtgtt tatttcacca acttcttcat ctcatcaata
     2821 cgtgctacgg tcgcatcata cttagcttgg taatctgctt gcttgtcgcg ttctttttgg
     2881 acaacttctg gtttagcgtt ggcgacgaag cgttcgttgc tgagtttttt gccaaccatg
     2941 tcgagttctt tctgccattt ggcaagttct ttttccagac gtgccaattc ttcttcgaca
     3001 ttcaagaggt ctaccagtgg caagaagatt tcggctcctg tgatgacgct tgacatagcc
     3061 agttcaggtg cagggatggt tgatgcgatt tccaagtgtt caggatttgt gaaacgtttg
     3121 atgtagttga cattgctgtt aaagaaggct tccaagtcgc tatcgcttgt cttaacaagg
     3181 atagtgatag gcttgcttgg agcaacgttt acttccgcac gcgcattacg aacggcacgg
     3241 atcaagtctt taaggctttc cacaccagtg tgagcagcaa ggtcttcaaa ggctgggttg
     3301 atagttgggt attctgctgt aacgatagat ccttctgaga tttgtccaaa gatttcctct
     3361 gtcacaaatg gcatgattgg gtgaaggaga cgaaggatct tgtccaaagt gtatagtaga
     3421 acagaacgtg tgatgacttt ctcttcttcg ttatcgctat aaaggacttc cttggtcaac
     3481 tcaacatacc agttggcaaa ttcttcccag atgaagttgt aaaggatatg accagccaca
     3541 ccaaactcga acttatcaaa gttttcagta acttttgcaa tggtttcgtt gagattgtgg
     3601 agaatccagc ggtccgtcac attaccagcc tcacctgttg caacttttgt gacattgtca
     3661 tgcgccacat ccagcgtcaa accttcattg ttcatgagga tatagcgaga aatgttccaa
     3721 attttgttaa taaagttcca tgaagcatcc attttctcgt aagagaaacg agcgtcttga
     3781 ccaggagctg agccgtttga caagaaccaa cgaagactat ctgtaccata tttatcaata
     3841 acatccattg ggtcaatgcc atttccaaga gatttagaca tcttacgtcc ttcttcatca
     3901 cgaattagac catggataag agcattttta aatgggctct ttcctgtaaa ttcaattcct
     3961 tggaaaatca tgcgtgatac ccagaaagga ataatatcat agcctgttac gagtgttgaa
     4021 tttggatagt agcgtttaaa gtcagtagtt tcggtattag gccagcccat ggttgagaag
     4081 ggccagaggg cagagctgaa ccaagtgtca aggacatctt cgtcctgttt ccagccatcg
     4141 cccgctgggg cttcctcgcc gacatagatt tcgcctgctt cattatacca agcagggatt
     4201 tggtgacccc accaaagctg acgagagata acccagtcgt ggacattttc catccattga
     4261 aggaaggtat cgttgaaacg aggtgggtag aattcgacct tgtcctctgt gtcttggttg
     4321 gcaatggcgt tcttagccaa ttggtccatc ttgacgaacc attgagtaga caagcgtggc
     4381 tcaactacga cacctgtacg ttctgagtga ccgactgaat ggacacgttt ttcgattttg
     4441 acaagggcac cgatttcttc caacttagca acgactgcct tacgagcttc aaaacgatcc
     4501 atgcctgaaa attcaaaggc aagctcattc atagttccgt cgtcgttcat gacgttgact
     4561 tgtggcaagt tatgacgttg gccaaccaag aagtcatttg gatcgtgggc aggtgtgatt
     4621 ttcacgacac cagtaccaaa ctcaggatct gcgtgctcat ctccaacgat tgggatgagt
     4681 ttattagcga ttggaaggat gacgttttta ccaatcaagt ccttgtagcg cgggtcttct
     4741 ggattaaccg caaccgcaac gtccccaaac atagtctcag gacgagttgt agcaacttca
     4801 agggcgcgtg aaccatcttc cagcatgtag ttcatgtggt agaaggcacc ttcgacatcc
     4861 ttgtgaatca cctcaatatc agaaagggct gtgcgagctg ctgggtccca gttgatgata
     4921 aactcaccac ggtagatcca gcctttcttg taaaggtcca caaagacctt acgaacagct
     4981 tttgacaaac cttcgtcaag agtgaaacgc tcacgagagt agtctacaga gagccccatc
     5041 ttgccccatt gttccttgat agtagtggca tattcgtctt tccattccca gactttcgtc
     5101 aagaaagact cacgaccaag gtcatagcgg gaaatgccct caccacgcaa gcgctcctct
     5161 accttagcct gagtggcaat ccctgcgtgg tccatcccag gaagccaaag ggtatcaaaa
     5221 ccttgcatgc gtttttgacg gatgataata tcttgcaaag ttgtatccca agcgtgacca
     5281 aggtgaagtt tacctgtaac gtttggtggt ggaataacga ttgaataagg cttagccttt
     5341 tgatcgcctg aaggcttgaa aacatcagca tcaagccatt tttggtaacg accagcctca
     5401 acctcggctg gattgtattt agatgaaagt tctttagaca tgtgtgtgtc ctttctctat
     5461 tttgtttatt ttattttgaa tctgcttagc agcttcttct gcagacaaat tcgtattatt
     5521 tattttaaag tagtggtgca actcattcgg ttgatattgg gaatttaatt gaagtgtttc
     5581 agcggtctct aaaatttctc tttcagatac ctcaatatgt cgttttaagg gtttgtgctt
     5641 taatcgattc tccgttcgat ttcgacgtat gcactcttca agacttgttt ccaactcaac
     5701 aaaaagaatc tcttgatgat aatcatccaa caaattctga atttgcttta aatatatcag
     5761 atgatactga tttgaaaaat caattacatc tgttaaaatt actgatcgct gatttcttgc
     5821 acttgctcca aggaatgaaa aagtgattcc acgaacaaat tcccacattt cctctgtata
     5881 gtcctgatag atttctagtg caaaatcaat ggcttgatgg ttataaaata gggtagcatc
     5941 cgtcagtcga gataattctt gaccaatggt catttttcct gatgctggag caccaatgat
     6001 gaaaagatgc atcaaatcac ctcccactcg ctcttcagca agccatatat cagactgtca
     6061 cagcggtttc cttgaacatc ctttcggtct cttatgcgag cttcgagggt aaagccaagc
     6121 ttttccgcga ctcgtttact ttgaaggtta tatccaaagc aagttagttc aatcttgtga
     6181 agacccaaat ctttaaaggc taagtcaatc aaggcacgcg cagcttctgg cacataacct
     6241 cgcccccaat agtctgggtg taaggtatag ccgatttcca gcacatcatc ttcatggcga
     6301 tggttgaaat cgacagagcc aacgatctta tccgttcctt tgacgacaat cccgtagcct
     6361 gctgggagat tttccttttg attacgctcc ggaagaatgt gctccagata ataaatctca
     6421 tcttccaagg tcttgactgg aggaaaacct gctggatagg cgacctctgg caaactagca
     6481 tagtcaaaga tatcctcagc atccgccaca gtacggactc gtaaaacgag acgttctgtt
     6541 tcgattttat ctggcagctc agttcttgcc atccttcttc ctcgcttttt ttgatgaaac
     6601 tgcccttcat atctacacgc ttgtccagat agcgataaac gcgctgatat acatctccca
     6661 tgaaataggt tggggcaaac agttgatttt taaaatgtcc cttttcatcc aggagttctg
     6721 gggcaacaag tcgctcaaga atcttggcaa agatgtggca aataccgtct tcctcaacaa
     6781 tcctatctac ccgacaatct aaaacaagtg gacaggcgtc taaaatagga gtctgagttc
     6841 gttcagaaat ttcataatgc actcccaaac gttccaattt ctcctgatga ctgataaaac
     6901 cagcctgctc catcgcaagc atagaagttt catcagaaat attcacagta aatttttgat
     6961 actgtttgat ctgctctgcg gcattctctc tcgcaacgac tccaattaca acccaatctc
     7021 ctagactata cgaggaacta caggtcgtaa tgttatagcc aaaattctga tcttgatatc
     7081 ctaaaataaa aacaggaaaa ctataatata gtttattagt tttaaatgat tgttttataa
     7141 caacctcctt tgactaagac acaaaagaaa agccctgcca tctacatgac agggacgaat
     7201 gtatttatcc gcggtaccac ccaatttcgg gcagttgccc gcaactctcg tctttaaagc
     7261 aaaaagacac ttttatttca atttttcatc cattagcaac cagttttgac acatttgtgg
     7321 acttctcagc accgccactt tctgtaaaat gtgggattca aaacacctct aatggctcta
     7381 ttgtagcaag tttttctcgg aaatgcaagg ctcaagaaaa attacttgaa cttgatgcca
     7441 ttttctttca atttcttgat ggtagctggg ccgattcctt tcaaggcaag gagttctttt
     7501 tcagtccagt ttttgaaatc tgaagcagac ttgattcctt catcatagaa agtcttggca
     7561 cgatcaagtg gaagtccacc caagtttgct gcaaaatctt ctacagaatt agctactttt
     7621 tgagcttgct ctttggtagc ttctactgct tgttcaactt ttttagaaac tgccttacca
     7681 gctgcgcttg ctgactgttc tgcacgcttc acgacttttt ttgtctcatc tacaacctta
     7741 gtcacagtac ttgaaaaggc acctgcgcga cggaggccat ttcgtaattg ttttttacga
     7801 ttgagtttct ttgacatgat aaaatccttt caataaaaaa tccctgctct gacaaggatt
     7861 taacataaac attctatcaa gattttagtg aaaaatcaag aatctttctc gtttaataat
     7921 ttcgctcacc aaacaagcct tctggcaaat catggaatcc cttgcctgct ttgaagtttt
     7981 caaacttacc aagcaagaac tgataagcat ccaagcgact ctcgtagcga atcatggcat
     8041 ctttggcacg ctcgtcctgg tcttcttcgt aaactttttg gctttccttg tgcgccatgt
     8101 cgttaatcat gatttgggta ttgacccaag cttcaaattc cttcataaat tcttgttcgt
     8161 aactcatttt ttctccttat tctaatccac gaaaatagtc cgtatcaatc tcacggtagg
     8221 gctggatatc ctgaacgtat tccagtacac cttggaattc tccgttttca tcgtgtactg
     8281 cagcataggt gatgtggaca aacttgcctc gcgactcaga cttgaaccac atttcatact
     8341 tgtccttggt cccctcacga agtcccttca tgatagcctt gaccttgtcc aaatacttag
     8401 gcggatgaca gagttcgaca ttgcgcccga cttgggacgg cgtccgtttg aaaatcatct
     8461 catcagctgg cgtattgtca ttgtaatact ggaaaatatc ttctttattg acaaaggtaa
     8521 tctccatagg gagatgattg aggatgagat tggcctgctc gactgaaaga tagccattac
     8581 caaaagcctg ttgactatgg cggtccagca cagcttcctt ttccttaggg gtaaaggtaa
     8641 tggtaaaatg gccttctggc gtatctataa cttgttgaac ttgaccttct gccgtatcta
     8701 gctgtacagg ctcctctgca atcttttcct caataaagct ctgtcgttct ggcacccatt
     8761 tctctgacgg acggatgatg gcatagccat aggcatcgct ctcctccgca atctgaagcc
     8821 agtcatcctg agtaaaagac tcaaggagaa tcatgaggag gatggactct tccttgaaaa
     8881 tcatactttc aaactctatc gcaaaagctt caaaaacttc ctttacactg ctaattgaca
     8941 cttctggtag tgacttggct gtcgttagag ctgtttgaaa gagttcccta atctgatcat
     9001 ccactcccca cataactttg ggaggtgaat cgtgtccata gcgctccatg ataggaaaga
     9061 agagttcttc tttacgttgg taatggatgt caaattgccc cacaagtccc atctgacgca
     9121 ccaagccctt gcgcatctcc gcaagcattt cctcgtcttc catcaactca taggtatcta
     9181 acaatctacg aatgcgaatc aaagctgcac ggagggccaa attttcttcc ttaaagacac
     9241 gaactgggtg acctggatgc tcagtatctg aaacttcgac acctttgata gcatttttaa
     9301 aaagattggc atggacatca cagagttcca taacatcttc aaaggtgaca cctgagtctg
     9361 agttcataag ctcgtgctcc ataagggaaa tctcaatggc tgagacaccc gcaaaggtcg
     9421 catcaaaacg ctcctgaacc gactcaggag aggcgccatt atgcaattct aataaaatat
     9481 cccgtaggac atgaatccgt tcatctgcca ttagtctaat ccaatcactt cgtagccatt
     9541 cgcttccagt gtgcgtacaa tcttgtccat aggagttcct gctagcttag aaccctgttt
     9601 aagtgatact ttacgaccaa ctgtattgcg cattaaggga ttggcaaggg gtttaaaacc
     9661 caactccact agaatttcca agacttctgg atgcttgtcc accacttctg caacaggaat
     9721 tgacacatcg atgatattgt ccatgacgac ctccattgta tgttctaata ctcaatgaaa
     9781 atcaaagagc aaactaggaa gctagccgca ggttgctcaa aacagtgttt tgaggttgtg
     9841 gatagaactg acgaagtcag taacatatat acagcaaggt gaagctgacg tggtttgaag
     9901 agattttcga agagtataaa atgattttac tgcttatatt ataccatatg gaaagagaat
     9961 aaaaaactag cagtggagtt cctgctagtt ctctgcgact tggattacca tctagataag
    10021 tttaaagagc caatccaata tcttaaataa tatcttgtaa aacagcaatt ggactgcaaa
    10081 agaaatgatc atccaaaaga atttcacaat ctcaataatc ggtttgataa aaagaatagc
    10141 aagaagacca aaaaaatttc attctctctc ctctggctta atgagccacc gagccgtatc
    10201 cattagctta tctgcaataa agagttttcc cagaccaaca acgacatggt catctttctt
    10261 tatcgttttc atcactttta caccttgcac ggtcaaaaag taattaccat aaattttagc
    10321 tagagttttt atgagtccca tattactctc cttcgatgat ttcagcctct tttcggattg
    10381 tttcaacatc ttcttgatat tgaacttcac tatagttaac tagcttggac aattctttct
    10441 gcaagctttc acccatcggt ttcatagttg caaaggttaa accacctgaa atgataccac
    10501 ccaagatagg aataaatttc cccattcctt tggccagccc tcccttggta agattcacac
    10561 caaatattct taaaactttt ttcaaaataa gataccaaag cgtctttgtt aaagctttat
    10621 taggtactgt tttcattacc tgtttggcaa ttgttatacc accagcacgt agcaaagcag
    10681 cagttccatt cacccccaac atgacgccta gataaagcaa aagggtattt tgagcatctt
    10741 cactcaactc atcgcgtgaa gcccaaagat cctcataacc ataaatataa cctaattctt
    10801 gggccaattt cagagagaaa ccataaaatt gagccacatc agctggaatg gtaattgcca
    10861 tagcaagccc tccaggtaat cctgccaaaa cagaagtccc actcgctaat aaaacattat
    10921 ccctaataca ggcattagcc actcgatcta agatttcttg agataagaga gacgttggac
    10981 cttgttccaa taaggtagga atgtcctgtg gacccaattc tttggaaaac ttatccacta
    11041 aaaatttcga acgatcaacc ttaacaactg gtagttttac cacttgttgt aatacttgca
    11101 tagctaagtc ttgttcagcc atatacaaac tccttatttc ttttttacac cttatcatat
    11161 tatatttcct acaaaaaaag cattttctaa ttagataaca ttaaaaaata cagaacccct
    11221 tttttatagt aaaatgaaac aagaacagga caaatcgatc aggatagtca aatcgatttc
    11281 taacaatatt ttagaagtag aggcgtacta ttctagtttc aatctattat aaaagaatat
    11341 ttttccattt caaattcaac ctattttcct ccaccaaaaa agaggggcaa cccctcttct
    11401 ttagttctta tccagattgc gtagcatctc gtcaatcttg tttccatact cgatggactc
    11461 gtctttgacg aaggtcaaat ctgggatttt gtacaatttc aaattgcgac caagttcacg
    11521 tttgatggta ccagttgctt tttcaagccc gatttgggct ttttggttat ccgaagcaag
    11581 gttactcaaa atggtgtaat aaaccttggc aacagacaag tcacccagca tctgaacatc
    11641 tgtgatggtc acaccttgga cacgtggatc acggactttc ttttgcaaaa tctcattgac
    11701 ttcacgcttg atttccatgc ccacacgatc tgtacggaaa tgatttgcca tgatattcct
    11761 ttctctactt tgaaccaaaa gctaggccag cagacctagc tattttaaac ttcttgattt
    11821 tcagtttaaa ttgaaacgaa gttcaatttg aagtcatctg cttctttcgc cgtggtgaaa
    11881 gtgatggaac tgatttatca gtcccatcac gggggatttt tgagacccta ggctcaaaaa
    11941 taagcaatga aaccatcggt ttgcttgcgt ccctcaccac ctaagaaagg agcaaaaaat
    12001 cttatctctt gatttcttcc atgacatacg cctcaatcac atcatccatc ttaatatcat
    12061 tgtagccgtc gatcatcaat ccaccttcac ggccgtttgt aacttcctta acgtcgtctt
    12121 tatagtgttt caagcttgcg agttcaccat catagataac gacaccatca cggataacac
    12181 ggactttaga gtcacgggca accttaccgt tgataaccat aaatccaccg atagttccca
    12241 ctttagacac cttgaaggtt tcacggataa ccgcttcacc aataactttt tcttcaaatt
    12301 ctggatcaag catccctttc atagcttctt ccatctcttc gataaccttg tagataatgc
    12361 tgtgaagacg gatttccaca tcgtcagctt ctgcttgttg acgagcttgt ggtgtagggc
    12421 gtacgttgaa accaacgata aaggcatttg aagcttcggc aagggtcacg tctgattcgt
    12481 tgatagcacc gaccgctgag tggacgatag tcactttgac accttccacg tcaatctttt
    12541 gaagtgaggc agaaagggct tcaacagaac cttgtacatc agccttgatg ataacattaa
    12601 cagatttgag ttccccagct ttaagggtat caaagaggtt ttcaaggcta acacgttggg
    12661 tagcttgacg ttgtttcatg agggcacgtt tggcacgctc ttcacctgct gcacgcgcag
    12721 atttttcatc ctcgtaaacg gcaaagtggt cacccgccat cggtgcttcg ttcaaacctg
    12781 tgatagagac tggtgttgat ggtccagcaa ctttaacacg acgaccaagg tcgttggtca
    12841 tagcacggac acgaccgaag gtatttccga caacgattgg gtcttgaaca ttcaaggtac
    12901 cttgttgtac aagaagggtt gcgaccgcac cttttccttt atccaagcgc gcttcgataa
    12961 ccgtaccgat tgcacgcact gttgggtctg ccttgagttc ttggatttca gctacaagaa
    13021 ggactgtttc caacaattct tcgatatttt ggttgaattt agctgagatt tcaacaaatt
    13081 cagaatctcc accccaagca gttgacataa ctccatgctc tgccaattca ccgataacgc
    13141 gttctgggtt agcacctggt ttatcaatct tgttaatggc tacgatgatt ggaacgttgg
    13201 ccgcttttga gtggttaatg gcttcgatag tctgaggcat aaccccgtca tctgccgcta
    13261 cgaccaagat cgtaatatcg gtaacagaag caccacgcgc acgcattgat gtaaaggccg
    13321 cgtgtcctgg tgtatcaagg aaggtaatct tcttaccatt ttccacgatt tggtaggcac
    13381 cgatatgctg agtaatacca cctgcttcac ctgtcgcaac acgtgagtta cgaagagtat
    13441 ccaaaagggt tgttttaccg tggtcaacgt gtcccatgat agtaacaact ggtggacgct
    13501 caaccaattc atcttcattg agataaccat cttcgacaaa gaaacgttcg atgtcagcat
    13561 tatccacttc aaccttttgt ttggcttcga taccgtaatc caccatgagg agttcaattg
    13621 tttccccatc caaggattgg ttttgtgtgg ccatgacacc catcatgaaa agtttcttaa
    13681 caatttcagc tggttcacgt ttgatacgtt ttgcgatttc cgcaacggtc ataccatctg
    13741 tatattcaaa ttctgttggc aattcatgga atttacgctc cgtaacaggt tttggagtct
    13801 gattacggtt gttcttgtta ttgccttttt tgttcttttt gttgttattc cagttactat
    13861 tcttttgatt tctcacttga ttttgactac ttcgattctt ttgttgtttt ctaggaccat
    13921 cttcttcatg atcataatcg tcacgatttt tgtctggtcg agcttgtttt ttacgacgtg
    13981 tatccactgc aggttctttt ttctcaggga cgacttcaac cactgcttga acttgctgtg
    14041 cttgttcagc taacttagcc gcttcttcaa agatttcctc tggttccttg cgtttgttag
    14101 cttgagccaa ggcttcttta gcagcctgat actgcttgaa gcgttcctca cttgaacgag
    14161 cgtactctgc attttgctct gcttttaggg ctgctgcacg ggctttaaag tcaatacgtg
    14221 gagccgcttg atttgaacgt ttatcctctt gctgacggcg ctcatttcta cgtttttgct
    14281 gaccttgctg cttcttagct tggtcattaa agcgacgatt gtcgcggttg ctttgacctt
    14341 gttttccacc attacggccg tcgtttttct gacggtttcc gttttgttgt tggtcacggt
    14401 tattgccctt attttgcttg cgtcgttctg cctgctcttt agcacgggct tcacgctcag
    14461 ccttgaaatt acgactttgc ggtttcactg ctactttttc tgttttcgga gcaactggct
    14521 cagccggttt tgcctcttcc ttagctacag ctggtttagc tggctcagat ttttcggctt
    14581 tcttttctgc acttactttt ggtgctgcag gttttgcttc tactttcgga gcagctgcag
    14641 gcttaaagct ggcagcaatt tttgcagcga cagcttcttc cacacttgat gagtggcttt
    14701 tcacatccaa gcccaactct tttgcacgcg ctacaacttc tttactttct tttccaagtt
    14761 cttttgcgat ttcgtacaat cttttcttag acaaatcatg tcctcctctt ctattccata
    14821 agagacctca ttttctttgt aaatccagca tctgttacag ccaaaacctt tctcgatttc
    14881 ccgactgcta tgcttaattc cagtgttgaa aacacggtta caatttctac ttgataataa
    14941 tgacttttat cttgaatctt cttggtcaga ttgggtccag catcatgagc tagaaagacc
    15001 aacttggcct tgccgtcttg aatggccttg accaccaatt cttcacccga tatgatgcgc
    15061 cctgctcgct gagcaagccc caagagatta cttatctttt gcttattcaa gtcccaactc
    15121 tcttcttttc actttgtgat ccacataagc gatcaactcg tcataaaagc tttcttccac
    15181 ttccatgcta aagctgcggt taaagacctt cttctttttc gcctctaggg cttctgcatt
    15241 gtctagtttg atataagcgc cgcggccatt ggccttgccc gtaggatcaa taaagacttg
    15301 tccttccttg ttcttgacaa tgcggagcaa atcacgctta tcaatcactt cgttagacac
    15361 aacagacttg cgcaaaggga tttttcttgt tttcatcttt ccctcctcta gcagctttta
    15421 ttcttctaca gtatcgtttt ctacttccaa ctctactgaa gcagcgtctt ccatggcttc
    15481 aaattcgcta gcagacttga tatcgatacg gtaaccagtc aagtgagccg ccaagcgcac
    15541 gttttgtcca cgacgaccaa tggcaagaga aagcttgtta tctggaacaa ccaccaaggc
    15601 acgtttgctg tcgttttcat caaagataac ttggtcaacc tcagcaggag cgatggcatt
    15661 gtagataaat tcagctggat ctgctaccca ctcgataaca tcgatatttt cttcgattgg
    15721 taccatgcgg tcatttttag catcgtaacg agctgggtgg aatttgctag taatcttctt
    15781 gatattagca ccaccacgtc caacgattgt accgatagca tccacgtttg gattgtggct
    15841 acgaacagca accttcgtac ggtcacctgc ttcacgagcc acgctcatga tttcaacagt
    15901 tccatcataa acttctggaa tttcttgctc cattaaacgt ttgatcattt ctggatgact
    15961 acggctaaca aagacgttca caccacgagg gttgtcttca accttgtaaa cataaacttc
    16021 gatacgatca tgagaagcaa aaacttctcc aggaatttgg tcttgttttg acaattgggc
    16081 ttcgatgcta ccaaggttga catagataaa gcggttgtca aagcgttcta ctgtaccaga
    16141 catgatttct tgctcatgtt ctttgtaagt attgtaagtg atggcacgtg tttgcttgcg
    16201 cattttttcc atgatggttt gtttggcaga ctgggctgct acacgaccaa actcagctgg
    16261 tgcttcttca aacttgattt tgtctccaag ttcataagct gaattaatgg caagagcatc
    16321 tttcaagctg atttccaaac ggctatcaaa tacttcatca acaacttcac ggacagtata
    16381 aactgtaaag tcacctgttt tttcgttgaa gtcaatagct acgctgtctg actgaccata
    16441 gcgtctgcga taagcggaac gaagcgactc tactactgcg tcgatgatat cttctttttt
    16501 gattcccttg tcttcttcca aaatgcggaa ggcctctagc atttctttac tcatgttttc
    16561 ttcacttttg aatcctcaaa agctatcctt tctttttcta taatttaact gctaaacgtg
    16621 cttttgatac taaactgtat ggaatttgga cggttttctt acgcgtcttg tccatatatt
    16681 ccatagtcaa ctcgtcctct tcgaaggcca acaaggttcc ttcaaagacc ttttgcttat
    16741 cgatggcttg gtagagcccg acatggatgt attttccaac cgctccagcg acggcatcct
    16801 tggttttcaa agggcgttcc aaacctggac tggtaatttc taggaaatat tgttctggga
    16861 agggatctgg cttgatggtg tctaggacag gactgataat ttctgtcaag tctgccgtgt
    16921 cgttcaaggt aattccttcg ggtttatcta caaaaatact gagaatcatg tcactgccaa
    16981 tctttccata ctcgatatcc acgagttcaa aaggagcttc tatgacaggt tctacaactt
    17041 ctctgactaa ttctacgatt gttgcgattg cgtccacctc ctcataagca agaggcgaag
    17101 atatttcccc gcctcacttt tcatattctt actatcagta tagcacgttt gccaacttat
    17161 gtaaagcaaa agcacttgta cagcctaatt ttaggctatc tcttaaaatt ctgcctcaac
    17221 tcggtagata acttgcccct tgtttgagaa tttttgctcg tattctgtca tgacattgcc
    17281 ttcaaaatca ctggcatgca aatctaacca gacaccattg agtttcatgc catattgaga
    17341 aaagctcact aaactgtact caaacaagcc acggttatcc gtcttgaaat gaatttctcc
    17401 attttcaggc aagatacgtt tgaaggtatc caagaaggtc ttgtaggtca aacgacgctt
    17461 ttcatggcgt tttttcggcc atggatctga aaagttcaga tacaagcgat caatctcacc
    17521 gtcttcaaaa tagtcagtta agtcagaacc atctacccac aagagcttga tgttaggcac
    17581 tccaacttca agcaccttgt ccaaagcgta gctcaaaaca gacttttgaa tatcaatccc
    17641 gatatagttg atgtcagggt tttgcttggc catacctgaa acaaaggcac cctttccact
    17701 tccaacttcc acatgaatgg gattatcatt gccaaacaag tcccgccatt ttgccttggc
    17761 ttccaaggga ttgaggacca catactgggg atttgcctct agtaattctg ttgccccttt
    17821 acgatttcta actctcatct tctctttcca tacttgtctc ggaaatgacg caaaccatga
    17881 atctcccgat tgacattttc taaatcttgg ttcatataat acttggaaat ctgactcaaa
    17941 taagacaatt gaccatacca atacaattta cttaataccg tttgattgta cttgtaaccg
    18001 tagtaggtca accattcctt ccactgatgt tctgaaatat aatggcagag catatgggcc
    18061 acatcaaaca tgcgatcggt caagcgaacc gaatcccaat ctactaaata aatcaagcca
    18121 ctatctgtct caatccaatt actatgtcgt acatctccat ggacaatggt cgcatggtcc
    18181 tctctaaatc ctggaatagt ctgacgtaaa tcagccatca cttcactgat aaaatgattt
    18241 ttacgcaaag catctggagc cgtttcctgc caagactgta gtaaatctac aggtgtttcc
    18301 atggcatagc ccaaacgact caattgtgtc atcaacggac gtgagcgatg aagacgggtt
    18361 aaaatattga cgatttgctt acgattcata tcataggggg tcaatatctt gcctgtcaac
    18421 cattcttgag cacacatatc acgcccatct gccaaacgac gactccataa taattgtgga
    18481 gcaatttgtt ctctagctag accaggtagg attggagagg tgttcatttt tacaaagatg
    18541 cgcttcccgt caggatagct acccatataa gccttgccac ttttcccagg tatgggagtc
    18601 agtgttagct cattatcacc caaatccatt tctttcctcc gtataaagtt tccttactat
    18661 tctactagtt tttggcctat tcgtcaacca ctctaacccg attctcaaag aaaagcctct
    18721 ggattggctt gggtatcatt atagcttgaa aaaggtaagc accatcttct gcttaccttt
    18781 tcataatttt tataaataat ataggagtgg ccaactgttg taaaacatgt ggactagagt
    18841 agaaacccat aggttttgac tctttttata agcaaagccc agcaacaaac ccccaagtag
    18901 ataaaaaata aacgaaggga cattagaagg tccatgcatg aaagaaaaga gagaggaagt
    18961 tagcacaagc cctaaccaag aattgtcaaa aaccgcacct tgaagaagtc ctctgaaaat
    19021 gagttcctcc tggatggggc caaaaactga ggtagtcaaa atcaaagaca gggaaattcc
    19081 tctgctgact tccgccaagt gttggacccc tgagccagaa gaaacagcga agaaatgaat
    19141 ataaaccagc gtctcaagta cacttagaag aaagattgca atgaaaagca aaagttgttt
    19201 cttgcttaac atcccaaaag aaatcatttc aaactttcta gcataagcaa cactcagcga
    19261 ggttacaaga agacttacaa gaatcaatgc agattcattt tgaaaaaaac ccccatggtt
    19321 aatcgtataa ggaactgtaa tgacaattat tagtactaaa aatccaaaac acaaggcatg
    19381 aaatttatca acccaaatca ttcatacctc tctcaactag atgtaactta caaaacccct
    19441 gacctcatga gccactttct tcctcctcat gaggtcagtt ttactttctg ctgttccagt
    19501 atcgtttttc ctcgctagat ttcctcaaaa gggcagactc ctcccttggt
//
LOCUS       DAVLIK010000035        18814 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLIK010000035 DAVLIK010000000
VERSION     DAVLIK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.035"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(314..1120)
                     /gene="yidA"
                     /locus_tag="VXE87_001456"
     CDS             complement(314..1120)
                     /gene="yidA"
                     /locus_tag="VXE87_001456"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0842983.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1133..2437)
                     /locus_tag="VXE87_001457"
     CDS             complement(1133..2437)
                     /locus_tag="VXE87_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0842984.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSLIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2509..2886
                     /locus_tag="VXE87_001458"
     CDS             2509..2886
                     /locus_tag="VXE87_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0842985.1"
                     /translation="MKIRMRNTIQFDEQLEVIDRLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2977..3309
                     /locus_tag="VXE87_001459"
     CDS             2977..3309
                     /locus_tag="VXE87_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0842986.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            3321..4892
                     /gene="ffh"
                     /locus_tag="VXE87_001460"
     CDS             3321..4892
                     /gene="ffh"
                     /locus_tag="VXE87_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0842987.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVCHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5087..6370)
                     /locus_tag="VXE87_001461"
     CDS             complement(5087..6370)
                     /locus_tag="VXE87_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0842988.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6624..7337)
                     /gene="rsmG"
                     /locus_tag="VXE87_001462"
     CDS             complement(6624..7337)
                     /gene="rsmG"
                     /locus_tag="VXE87_001462"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0842989.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7431..7991
                     /locus_tag="VXE87_001463"
     CDS             7431..7991
                     /locus_tag="VXE87_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0842990.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            7993..8892
                     /gene="htpX"
                     /locus_tag="VXE87_001464"
     CDS             7993..8892
                     /gene="htpX"
                     /locus_tag="VXE87_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0842991.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(9041..10600)
                     /locus_tag="VXE87_001465"
     CDS             complement(9041..10600)
                     /locus_tag="VXE87_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0842992.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRNLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKILHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGSLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLKQFLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(11015..11155)
                     /locus_tag="VXE87_001466"
     CDS             complement(11015..11155)
                     /locus_tag="VXE87_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HEV0842993.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKQ
                     KS"
     gene            11325..11867
                     /locus_tag="VXE87_001467"
     CDS             11325..11867
                     /locus_tag="VXE87_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0842994.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            11867..12496
                     /gene="nth"
                     /locus_tag="VXE87_001468"
     CDS             11867..12496
                     /gene="nth"
                     /locus_tag="VXE87_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0842995.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            12707..13228
                     /gene="pyrR"
                     /locus_tag="VXE87_001469"
     CDS             12707..13228
                     /gene="pyrR"
                     /locus_tag="VXE87_001469"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0842996.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            13247..14170
                     /locus_tag="VXE87_001470"
     CDS             13247..14170
                     /locus_tag="VXE87_001470"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0842997.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            14220..15299
                     /gene="carA"
                     /locus_tag="VXE87_001471"
     CDS             14220..15299
                     /gene="carA"
                     /locus_tag="VXE87_001471"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0842998.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            15612..18788
                     /gene="carB"
                     /locus_tag="VXE87_001472"
     CDS             15612..18788
                     /gene="carB"
                     /locus_tag="VXE87_001472"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0842999.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         5462 a         3621 c         4230 g         5501 t
ORIGIN      
        1 ctgtaagata tgataaagtc ttatttttag tgaagtatcc taatttgtat aattgattgt
       61 gtgtagattc agggtcaatt tgaagagagt atttaaaata tcttgggaaa ttataatttc
      121 tccctgtttt ttgagtccaa tctatgagta tgagttgccc aggagtaagg ccacattcta
      181 attcgtttag gtaaaaattg ttacaatcag aatttgtgtc tctattatga ttattttgtt
      241 ttaaattaaa tagtttgcta aaaaaattca ttggatttta ttgctaatca attcttattg
      301 aaaaatgata cttttacagt acccatgttc ggatggcgtg ggcaacgccg gattcgtcat
      361 ttgttttagt gatgtatttg gcgatttttt tgatttctgg atttccattt tccatgacaa
      421 cggggtttcc aacgacttcc agcatggcac ggtcattttc ttcgtcaccg attgccatgg
      481 tttcatcttt ggtcaatccg agtttttcag ccaagtgagt aatggctgaa cccttgtcta
      541 cattctttgt aaggagttcg aggtagaaag gagcagattt gttgatggag tagcgctcgt
      601 aaaattctgc tggaattttt tcaatcgcag catcgagaat ttctggttca tcgataaaca
      661 tacatttaac aatttctttg ccagccattt cttcaggggt acggtagaag ataggcatgc
      721 tgacgagggt tgattcgtgt acagtgtatt ttccgatatt gcgatttgca gtatagatac
      781 cgtccttggt aatggcatgc atgtggacac cgagcttgcg actgaggaat tccatatcca
      841 gataatcctc ataggtcaag gattcgctga taatctcatg gccagtagca gtttcttgga
      901 caagggcacc attgaaggtc accacatagt caccttggtc tctcaactgc aagtcgtcca
      961 gaagtttggc aacacctgcg atggggcggc cagttgcaat cacgactttg acaccagctt
     1021 ctttggcatc ttggatggca gaaaagactt caggagtgat ttccttttgg ctgttgacta
     1081 gggttccgtc aatatcgacg gcaattagtt taatactcat aaatttcctc ttctagtttt
     1141 tatttggggt aaaatgatcg ttctcaatca agtgtaaaaa ttgctgggta atgcttgcga
     1201 agatgctgtt ttggtctaac atttctttag ggaaatagaa acgattatct ccgtggcgac
     1261 tgccagcaag ggattggacg ataagagaca ggctagagag ttcggccagt tctccatttt
     1321 tttgtaaaat ctcaatctgt gtccgtgggt tttcagattc gggacgatag atatcataag
     1381 ggaggtcaaa gttcttatga atggcagtgt agtagtcggg atcaaagccg atatcctcag
     1441 ctaattttct catgctggcg agttggtctt ggtcctcttg tgaaaaggta atggatttaa
     1501 agaccttgcg gttgacaaag cgttgtgaca agtctgcgag aatcttgtca ggactggtca
     1561 tccagagttg aaagtaggta ttcatcacac catcatctag agccagatag tcagtcaagg
     1621 tcacattttt ttcaaagaaa ggcaggaggt gtggagaagt tcgtgcaaag aagtccttgt
     1681 cttcaggata gagttccttg gcgcgtttga gaagattctg taggagaact tccatggcgc
     1741 gtgttgcggg gtggaaataa acctgcatgt acatctggta gcgactgagg acgtagtctt
     1801 cgatggcgtg catgccattg cgctgaaagg cgataccatt ttcgatagga cgaatgactc
     1861 ggaggattcg agtcaggtca aattccccat aggatgctcc tgtaaaatag gagtcacgca
     1921 agagatagtc catgcggtcc gcatcaatct ggctagaaat gagctgcacg acctgcttat
     1981 taggataggt atggtcaatg acactggcca ccttttctgg gaaatcaggt gccacttgta
     2041 gcaggacttg gtgaatctct gtctcaggat tttgaataat ctcctgagta atggcttcat
     2101 ggtctgtatc aaagagattt tcaaaagtat gggagtaggc accatgccca aggtcgtgta
     2161 ggagagcagc ggtcatggtc aagagagact cggcaggatt ccattcctca ggatattttt
     2221 cttcgaaaat ctctgtgatg cgtcgtgcaa tttcatagac tcctagacag tgagagaagc
     2281 ggctgtgctc tccaccgtgg aaggtataac tggaggttcc cagttgcttg atacggcgca
     2341 aacgctgaaa ttcttttgta ttaatcaagt catagataat ttgattattg acatggatgt
     2401 agttgtgaac tgggtcacgg aatacttttt cgttcatatg accattatag caaaatcctg
     2461 ctctttttgg taaaatagta ggacaagaga caagaaagag ggcctgatgt gaagattcgg
     2521 atgcgaaata caattcagtt tgatgagcag ttggaagtga ttgaccggct ttatgatgtg
     2581 gaagtgcatg aaaaaggaga ttatagctac ctgcttttct ataatgagga aaaggaaaaa
     2641 gtagtgatta aatttcatgg tcaagaactt gtgatgagcc gattttctaa tcccaagacc
     2701 attatgcgct ttctaaagga tagcgatagt ttagcctata ttcctacacc tatgggcatg
     2761 caggagttta tcatccaaac gagccattat caagttgata ggcaaaagat tgaactagat
     2821 tatcaactac aaaatcaaga gggacatcct tttgccagct atcaattgga aattacttgg
     2881 ggctaggctc atgtcttttt caaatttagc tatctatctt cttggatcgg cttcctagtg
     2941 tggtagatta ggctaatttt tggtataata aaagttatgg aaatcgaaaa aaccaatcgt
     3001 atgaatgcgc tctttgaatt ttatgcggcg cttttgacag ataagcaaat gaattatatc
     3061 gagctctact acgctgatga ttacagcctt gctgaaattg ccgaggagtt tggtgtcagt
     3121 cgtcaggctg tctatgacaa tatcaagcga acagaaaaga ttctggaaga ttatgagatg
     3181 aaattgcaca tgtactcgga ctatattgtc cgcagtcaga tttttgatca gattttggag
     3241 cgctatccca aggatgactt tctgcaggag cagatagaaa ttttaacaag cattgataat
     3301 agagaataag aggaagaaaa atggcatttg aaagtttaac agaacgtttg cagaacgtct
     3361 ttaaaaatct acgtaaaaaa ggaaaaatct ctgaatctga tgtccaagag gcaaccaaag
     3421 aaattcgctt ggccttgctc gaggccgacg ttgccttgcc tgttgtaaag gactttatca
     3481 agaaagttcg cgagcgtgca gtcgggcatg aggtcattga tacacttaat cctgcgcaac
     3541 agattattaa aatcgttgat gaggaactga cagccgtttt aggttctgat acggcagaaa
     3601 ttatcaagtc acctaagatt ccaaccatca tcatgatggt tggtttgcag ggagctggta
     3661 aaacaacttt tgcaggtaag ctggctaaca aactcaagaa ggaagaaaat gcccgtcctt
     3721 tgatgattgc ggcggatatt taccgtcctg ctgccattga tcagctgaag acactgggac
     3781 aacagattga tgtgccggtt ttcgctcttg ggacagaggt tccagctgtt gagattgtac
     3841 gtcaaggttt ggagcaagct caaactaatc ataacgacta tgtcttgatt gatactgcgg
     3901 gtcgtttgca gattgatgag ctcctcatga atgagcttcg tgatgtgaaa gcattggctc
     3961 aaccaaatga aatcttgctt gtcgttgatg ctatgattgg tcaggaagca gccaatgttg
     4021 cgcgtgagtt taatgctcag ttggaagtga ctggggtcat ccttaccaag attgatggcg
     4081 atactcgtgg tggtgctgct ctgtctgttt gtcacattac tggaaaacca atcaagttca
     4141 ctggtacagg tgaaaagatt acggacattg aaaccttcca cccagaccgc atgtctagcc
     4201 gtatccttgg catgggggat atgctcactt tgattgagaa agcttctcag gaatacgatg
     4261 aacaaaaagc ccttgaaatg gctgagaaga tgcgcgaaaa cacctttgat tttaatgatt
     4321 tcatcgatca attagatcag gtgcaaaata tggggccgat ggaagacttg ctcaagatga
     4381 ttccaggtat ggccaacaat ccagcacttc aaaacatgaa ggtggatgaa cgccagattg
     4441 ctcgtaaacg tgcgattgtg tcttcgatga cacctgaaga acgtgaaaac ccagatttgt
     4501 taaatccaag ccgtcgccgt cgtattgctg ctggttctgg aaatacattc gtcgaagtca
     4561 ataaattcat caaggacttt aaccaggcta aacagctcat gcagggtgtt atgtctgggg
     4621 atatgaataa aatgatgaag caaatgggga ttaatccaaa taaccttcct aaaaatatgc
     4681 caaatatggg aggaatggat atgtctgccc ttgaaggaat gatgggacaa ggcggtatgc
     4741 ctgacttatc agctctcgga ggagcaggaa tgccagatat gagccagatg tttggtggcg
     4801 gtttgaaagg taaaattggt gaatttgcca tgaaacagtc catgaaacgt atggctaaca
     4861 aaatgaagaa agcgaagaag aaacgcaagt aagacaagag attgatgcaa atctcatttg
     4921 atgagaaaat aaagtaaaaa tttctatgat aaaacgtaca gtatcaaggt tttagaatat
     4981 ctgatattat acgttttttg attttaataa ttttgttaag acacttttat tatggtatac
     5041 gaaaaatcca ctcagctgtc tgagtggatt aggtgtattt agactcttag tctttatttt
     5101 cgtatggcaa gatcaagttc aagatgattc ctgtcatggc tgaaagggca gtacctgaaa
     5161 gtgtaactgg accaagttta aggatagctc ctccaagtcc aagaaccaac atagcacttg
     5221 cgatgatgag gtttcgcatt tgagcgaaat caacacgttc tttaatcaag actttcaaac
     5281 cattgctggc gataacccca tagagaagga ttgacatacc accaagtaca gcgtttggaa
     5341 tagttgaaat caaggcagtg aatttaccaa ggaagctgag ggcaatcgcg atgaaggcag
     5401 cgttacggat aactgagaca gaagcgatac gagtcatacc gataacccct gtattttctc
     5461 cgtaagttgt attggctggt ccaccaagga aggcagaaac agaagttgcg ataccgtcac
     5521 caagaagagt acggtgaaga cctggttctt ttaagaattg acgaccacag atttgaccca
     5581 aaacagtatg gtctccgata tgttcagaaa ttgttacgat agcgattggc aagatagcga
     5641 tggcttctgg accaaagtaa agattgtact ctttaaaggc accacctgtg ctaaatggca
     5701 agtagaaacc aggaatttca aaccagttag cttctaggac aggtgtaaag tcaaccaagc
     5761 caagagttag tgcgaaaagg taaccaccga taatggcaaa gaggaatgga atgattcgta
     5821 ggaagccttt tccttttgta ttgataaagg cagcaattag gaaagtaaca acggctacca
     5881 gagcattttt ccaatttccg tctgctacaa gacctgcatt ggtaacagct gaacctgcaa
     5941 gtccaagacc gataacgatg atcataggac cgataatgat tggtggcaag agtttatcaa
     6001 tccattttgt tcctacaaat cggatgctgg tagcaacaag gacatagacc aaaccagtca
     6061 agataacccc tgtttgggca gcagatacat ccccccccat ttctttcata gccagtgaca
     6121 tagctgtgat aaaggcaaat gaagaaccta gataaactgg aactttaaaa ccagtagcaa
     6181 tcatgtagat gagtgttcca acacctgaag caaaaagggc aacagataca ggcattccca
     6241 aaatcaatgg taccaagatg gtcgcaccaa acatggcgaa aacgtgttgg aaactaagga
     6301 gaattccttt tccatccgaa ggacgttggt caacgtctag taacaaatca acagttgatt
     6361 cttgtttcat ataaacctca cttttgggca tcagaaaaga gcccattatt ttacagcaat
     6421 aggccctcag agtaagactt ctctaaaatc tagactttaa agagtttcaa atatttctgc
     6481 gtcttcgtca cctcacggga tgacattaaa aacctttgct taggatagta tagcagaaaa
     6541 aaatgatttt gtaaatcatt ttttcccgag cctaaaaata agagagcgag gttgattttg
     6601 taaatatttt tttacttaaa aatttaaagc gggcgtttat ttggcatacc agccttacgt
     6661 ggatatttat ttggtgtttc ttttttcttt tctaccactg tgatgtaacg cggatctcta
     6721 tttggtaggg cgtagctgag attgtcttcg actttactaa aaaggagatt gagggcattc
     6781 ttagcttcta acaactcctc aggcgcattg ctggccttga gtgccaatag ttttccacca
     6841 accttaaggt agggaatagt caattcagat aggacctgca tacgggcaac cgcacgagct
     6901 gttacaaaat catattgagc acggaagttc ttgtcttggg caaaatcttc ggcacgtccg
     6961 tggtagaaat gaactccgtt caaatccagt tcttgagcca agagttgtag gaagttgatg
     7021 cgcttattga gtgaatcaat aatggtcaca tctaactccg gatagagaat tttcattggt
     7081 agactaggaa atcctgcccc agccccgata tcaagaagtt tgatagtttc attgggaatc
     7141 aaaccttgaa gaatgggtgc aatcgaatcg taaaaatgtt tgagataaac ttcttccttg
     7201 tccgtaatcg ccgtcaaatt aatcttctca ttccactcga ccaagagctc aaaataacgt
     7261 tcaaattgtt ctttttgctg gtccgaaagt ggaagattct gctcggcaag caagttgtaa
     7321 aatgtttctg gtttcatagt tatttccttc tttagtatca tcttatttta ccacaatcat
     7381 taaaaatttg atatactggt actaatctaa aagtagaaag gacttatatc atgacttgga
     7441 ttattcttgg agttatcgct cttattgtta tttttgtgat tgttagctat aacggtttgg
     7501 ttaaaaatcg tatgcaaacc aaggaggctt ggagtcagat tgatgttcag ttgaaacgtc
     7561 gaaatgacct cttgccaaac ttgattgaga ctgtaaaagg ttatgccaaa tatgaaggtt
     7621 ctacccttga aaaggtggca gaactacgta accaagtggc ggcagcgact tcaccagcag
     7681 aagctatgaa agccagtgat gccctcactc gtcaagtttc aggtattttt gcagttgcag
     7741 aaagctatcc agatttgaaa gctagtgcta actttgttaa attgcaagag gagttgacaa
     7801 acacagaaaa taaaatttct tactctcgtc aactctataa cagtgttgtc agcaactaca
     7861 atgtaaaatt agaaactttc ccgagcaata ttatcgctgg aatgtttgga tttaaagcgg
     7921 cagatttcct tcaaacacct gaagaggaaa agtcggttcc taaagttgat tttagcggtt
     7981 taggtgacta agatgttgtt tgatcaaatt gcaagcaata aacgaaaaac ctggattttg
     8041 ttgctggtat ttttcctact cttagctctt gttggttatg cggttggtta tctctttata
     8101 agatctggac ttggtggttt ggttatcgca ctgattatcg gctttatcta cgctttgtct
     8161 atgatttttc aatcgacaga gattgtcatg tccatgaatg gagcgcgtga ggtggatgag
     8221 caaacggcac cagacctcta ccatgtagtg gaagatatgg ctctggtcgc tcagattcct
     8281 atgccccgtg ttttcatcat tgatgatcca gccttaaatg cctttgcgac aggttctaat
     8341 cctcaaaatg cggctgttgc tgcgacttca ggtctactag ctatcatgaa tcgtgaagaa
     8401 ctagaagctg ttatgggaca tgaagtcagt catattcgta attatgatat ccgtatttcg
     8461 actattgcag ttgctcttgc tagtgctatc accatgcttt ctagtatggc aggtcgtatg
     8521 atgtggtggg gtggagcagg tcgcagacga agtgatgatg accgagatgg aaatggtctt
     8581 gaaatcatta tgctagtggt ttccctacta gctattgtac tggcacctct cgctgcaacc
     8641 ttggttcagc tcgctatttc tcgtcagagg gaatttctgg cagatgcatc tagtgtcgag
     8701 ctgactcgca atccccaggg aatgattaat gccctagata agttggacaa tagcaaacct
     8761 atgagtcgcc acgtcgatga tgctagcagt gctctttata tcaatgatcc caagaaaggt
     8821 ggggggttcc aaaaactctt ttatacccac ccacctatct cagaacggat tgaacgttta
     8881 aaacagatgt aaaatgaagg ctggaaaaaa gtctttaaaa tctgaaaaac gcataatatc
     8941 aggtgtgaaa acttgatatt atgcgtttta ctatgggaag atttacttct ttttctccta
     9001 aaattgtgtt tttgccccac ctatctgcta tgttgcaaat ttataaatct tctaaattaa
     9061 ctagcttcaa accgtgttct gtcatgcgat agatgatcga gcagacttct tttaagaaac
     9121 gacggtcatg cgaaacagtg atgagaccgc caggataagt ggcaaagagt tttctgattt
     9181 ggggttgaga agtgggagaa aagtttcgtg tgggttcatc cagcaggaga aagtttggtt
     9241 tgcgcaggac taaatccaaa agcaggagtt ttccctgttg tccgccagat aaggagcgaa
     9301 tttgatgctg catttctgga taactgaaat tgagactagc taggtgagat tggattttct
     9361 gtagttcctc tttttcccca gttttgctga ggtaggctat tggtgataaa tccaattgca
     9421 gttttttgtg gtaatcttgt ggcataaaac caagggaaat ctctctttta tcattcagaa
     9481 attgctttaa tttggctaac agagttgatt tcccaacacc atttggtccg ataataccga
     9541 ttttttcttg cccacggaca gttagttgca gttcctgagc caaaacacgg tcgtcaatgg
     9601 acaaattttc tttttccagt tggactaaga ctttagaagc tggtaatggt tggatgtctg
     9661 aaaagaaaag ttggatttgt tcctcttcaa gtggcttttg agtcatggac tgagctgcct
     9721 tttcgtagcg tttttcttgt gagaggacag ttttcatctt tttagccaat aggcgaccgg
     9781 cagtactatc tttggtagct cgaagcgcag tttctacatt ttgcttaact ctccgatgtt
     9841 tttccatggt tttatcgtag gctctttggt tgttagcagc ttgctgactt tgtttggcaa
     9901 aattagcctt tctctgctca ctatagctat catagtctaa atgctctact agcgtttccg
     9961 cttctttacg gtgtttgacc agtcgcaagt gaacaatagt gtctgccgtt tcagaaagaa
    10021 agtcttcatc atgggaaatg aaaataacgg tttgcctggt cttttgaatt tggcctttta
    10081 accaatcaac tgtctcaagg tctaggtcat ttgaaggttc atctaaaaat agaatctcaa
    10141 agggtttggc taactcatgg ataagctgaa ttttcaaagc ttcgccccct gatagactgc
    10201 caatctcttg gtcacttgcg aaacgattgc tatcaaaatg caattcctcc gccaaacgat
    10261 agaggatact gtagtctaaa tcaatagaat ctaaaaagaa gtagtcgtgt aaaattttct
    10321 ttttcagttc ctcgggaagt ttttgaggaa tgtaggccag tgactgatag tcagattgga
    10381 tgtttccctt gatagtgaaa tcagacaaag cttcccccat taaaatttta agtaaggttg
    10441 atttaccatt tccttcttcg ccaataatag ctaccttttc cccgtcttgt atggtcatgc
    10501 ttaggtcaga gacaaggttt cgtaaatctt tgttttgtgt gatggtcagg tgattgattt
    10561 ttatcatact attgcccttt ctagaatgtc gatagtgcat aacaaaaagc tctactttac
    10621 ctagtagagc ccaaagtcta tgtcaaaaaa actctattaa catgccagaa aaagagcata
    10681 aaagagcaca caaaaagaga caaaaacaag atctactaaa taaaggttct ttatttgata
    10741 gacttagttg ttcatgtctc ccttacctcc gagtattagt atctttatac tatactttta
    10801 aggaaatttt gtcaacagaa aactggaaat tctatgctct aaaatccaaa aacaggtcca
    10861 tagagactta gtacgtgttt gacatgctcg taatggattt tatcatagtt tcgccaagca
    10921 gtgcgttctt gattgtttag ttttaggcta cccagtccaa tcagaggact ggtgggttgg
    10981 taaaatttct caagatcaat taagatactg ttgttcaact tttctgtttt ttgagctctt
    11041 gcatagtagt gtttagcagc tcttgtagtc gaatatcatc tgccgtaccc tgtttacagt
    11101 tttggtagct tttatttaac ttggatagga gttgaatgag tttcttgtct tccatgtgag
    11161 catcctcctt gatctgatgt actctttccc tatagtatag cactaaaaaa tgaaaatgtc
    11221 atagtgaata tgttaaaatt tcgaatttta attacaaagt ttggtgtgct gatttgtagc
    11281 cttttcatgg tataatcaag agagtaaatc tttatggagg aagtatgaaa ttaaatattc
    11341 aagaaattcg taagcagtct gaaggtttga actttgaaca aacgttagat ttagttgatg
    11401 acctgcgtgc acgtaatcaa gaaattttag atgtaaaaga tatccttgca gttgggaaag
    11461 tccaatatga agaccgtatg tatttcttag attatcaact atcttatacc attgttcttg
    11521 cttcgagtcg cagtatggag ccagttgagt tagttgaatc ttatccagtc acggaagttt
    11581 tcatggaagg cgcaactaac catctaaatc aagaaatttt agatgatgac ttggtcttgc
    11641 ccatcgaaaa tggggcgctt gaccttgctg agagtgtatc agacaatatc ttgctaaaca
    11701 ttcctatcaa ggtcttgacg gctgaagaag aagctggtca aggatttgtc tcaggaaatg
    11761 actggcaaat catgacagag gaagaatacc aagctcaaca agcagtaaag aaagaagaaa
    11821 acagtccttt tgctggctta caaggactat ttgacggaga tgaataatgg tcttgtcaaa
    11881 aaaacgagca cgaaaggtgc tagaagaaat cattgccctc ttcccagatg ccaagcctag
    11941 tcttgatttt accaatcatt ttgaactcct ggttgcggtc atgttatcag cccagacgac
    12001 agatgcagcg gtaaataagg ccacaccagg tctctttgtt gcctttccaa caccccaagc
    12061 tatgtctgta gcgacagaga gtgagattgc ttcacatatt tctcgcttgg gattgtatcg
    12121 gaataaagct aaattcctta aaaaatgtgc ccaacagtta ctagacgatt ttgatggtca
    12181 agtccctcag acacgtgaag aattggagag tttggcaggt gttggtcgca agacagccaa
    12241 tgttgtcatg agtgtaggat ttgggattcc agcctttgca gtggatactc atgtggagcg
    12301 tatttgcaaa caccacgata ttgtcaaaaa atcagcgacg ccacttgagg tggaaaagcg
    12361 ggtcatggat atcttgccgc ctgagcagtg gttagctgcc catcaggcca tgatttattt
    12421 tggaagagcc atttgccatc caaaaaatcc agagtgtgac cagtacccac aattatatga
    12481 ttttagcaat ttgtaagatg ctacattgaa actttttgct tgattttaag catgctttgt
    12541 gctatagtaa atgataacta aatattcctt taaacctgtc ccgtgaggca ggcaaggagc
    12601 gcgataaagt agaagggtga agtctatact gtgtgcagta gggctcgctt ggctataaat
    12661 ttcaagtctc cttgtttaag gagacttttc tttttggagg tttgtcatga aaacaaaaga
    12721 agttgtagac gaattgaccg tcaaacgagc gattacgcgt attacttatg agattatcga
    12781 acgcaacaaa gatttgaata agatcgtctt ggctggtatt aaaactcgtg gtgtctttat
    12841 tgcccaccga atccaagaac gtttgaagca gttagaaaat ctttcagttc ctgttgtgga
    12901 attggatact aaacctttcc gtgatgatgt taaaagtgga gaagatactt ctttggtttc
    12961 tgtcgatgtg acagaccgcg aagttatctt ggtggatgat gtgctctata caggtcgtac
    13021 catccgtgct gctattgata atattgtcgg tcatggtcgt cctgcgcgtg tgagtttagc
    13081 agttctagtc gatcgtggac atagagaatt gccaatccgt ccagattacg ttggaaaaaa
    13141 tatcccaacc agtcgttctg aagaaatcat cgtagagatg acagaacttg atgaccaaga
    13201 cagagttctg attactgaag aagcttagaa agttaaagga gtagccatgt cagaaaatca
    13261 acaagcattg aaccatgtgg tgtccatgga agacctcact gtcgatcaag taatgaaatt
    13321 gatcaagcga ggaattgagt ttaaaaatgg agcccagctt ccctatgaag accatccgat
    13381 tgtttccaat ctcttctttg aggattctac acggacacat aagtcctttg aagtcgcaga
    13441 gattaaactt ggattggaac gacttgactt tgatgtgaag actagttcgg ttaataaggg
    13501 tgagacactt tatgacacca ttttgactct gtctgcttta ggagtggatg tctgtgtgat
    13561 tcgccatcca gaggtcgact actatagaga attgattgct agtccaacga ttacgacttc
    13621 catcatcaat ggtggagatg gttcgggcca acaccctagc cagagcttgc ttgatttgat
    13681 gaccatttat gaggaatttg gccactttga gggtcttaaa gttgctattg caggtgactt
    13741 ggaccactca cgcgttgcca aatccaatat gcagattttg aaacgcttgg gatctgaact
    13801 ctttttcgct ggacctgagg aatggagaag tcaagagttt gcagactatg gacagtttgt
    13861 aaccattgat gaaatcattg atcaggttga tgtcatgatg tttctccgtg tgcaacacga
    13921 acgccatgat agtggagctg tattttcaaa agaagactac catgcccaac atggcttgac
    13981 tcaagaacgt tacgatcgtt tgaaagaaac agcaatcctc atgcacccag ctccaatcaa
    14041 tcgtgatgta gaaatagcag accacttggt tgaagcacca aaatcacgga ttgtccaaca
    14101 aatgaccaat ggtgtctttg ttcgaatggc aatcttagaa tccgtactag cgagtagaaa
    14161 cgccaactaa aacacaagat gttaaaagac gccagtgagc gtccacgaga ggtgaaaata
    14221 tgacaaaaag aattctagta ttagaagatg gcacagtttt tgaaggcaag gccttcggag
    14281 cagatattga tgtaacaggc gaaatcgtct ttaatacagg gatgaccggc taccaagaat
    14341 ccattacaga ccagtcttat aatggacaaa tcttgacctt tacttatcct ttggtaggaa
    14401 attatggtat taatcgtgat gattatgaat ccattattcc aacttgtaag ggagtcgttg
    14461 tttttgaaga agcgcgtaga gctagcaact ggcgcaacca aatgaccttg gatgaatttt
    14521 tgaaagccaa gaaaattcca gggatttcag gaattgatac gcgtgctctt accaagatta
    14581 tccgtaagca tggtactatg cgtgcaacct tgacccatgt tggggacagt atggaccatg
    14641 tgacggacca gctccaagca acagttttac cgacagacaa tatcaaacag gtttctacta
    14701 aaacgtctta tccagctcca ggagttggtt tgagcgtggt gctagtggac tttggtctca
    14761 agcactcaat cctacgtgaa ctttctaaac gcaactgtaa cgtgacagtt gttccttatt
    14821 cgacaacggc tgaagaaatt ctccatctca atcctgacgg agttatgttg tcaaatggtc
    14881 caggtaaccc agaagacgtt ccacaagcac tcgacatgat tcgcggtgta caaggaaaaa
    14941 ttccaatctt tggtatttgt atgggacacc aactctttgc aatggcaaac ggggctaaga
    15001 cctataagat gaagtttggc caccgtggat tcaaccatgc ggtacgtgaa atcgcaacag
    15061 gacgagtaga cttcaccagc cagaaccatg gttatgcagt cagccgcgag gatttgccag
    15121 agcacttgat tattacccac gaagaaatca atgacaagtc agtggaaggt gtgcgccaca
    15181 gataccaacc tgctttctct gttcaatatc acccagatgc agctcctggg ccacacgacg
    15241 ctagctacct atttgacgag tttatcgaga tgatggaagt ttttaaacaa tcaaactaag
    15301 aacgagtaaa agctcgtcgg agaatttatg taactgaaca cggacggaaa gctcagaatg
    15361 tagagaaacc aacttggatt gtcaatcctt ccttgatttc ctaaaattca atcgctttct
    15421 attcgtcctt tgtatcttat ttaatgtcgc cctgagaggc gacgaataga aaggagaagg
    15481 gtgctccgta tttgctgaac tgaatacggg ctacggacgg tgctaaaaag atagttattc
    15541 ctagaactga cagttcttcg tcataactcc tattttagct ttgtccgctt gacgccctta
    15601 atatcttata tatgcctaaa cgtactgata ttcaaaaaat tatggtgatt ggttctggtc
    15661 cgattattat tggtcaggct gctgagtttg actacgctgg gactcaggct tgcttgtcgt
    15721 tgaaagagga aggttatgag gttgttttgg ttaactcaaa tcctgcaacc atcatgacgg
    15781 acaaggaaat tgctgacaag gtttacattg aaccgattac acttgagttt gtgacacgta
    15841 ttcttcgtaa ggaaggtcca gatgccttgc taccaacact cggtggtcag acaggtctca
    15901 acatggccat ggaattatct aaaaatggta tcctagacga gcttggcgtt gaacttctgg
    15961 gtaccaaatt atctgccatt gaccaagcgg aggaccgtga cctctttaaa caattgatgg
    16021 aagagcttga acaacccatt ccagaatctg aaattgttaa cacagtagaa gaagcagttg
    16081 cctttgcagc gacaattggc tacccagtca tcgttcgtcc agcctttacc cttggtggta
    16141 ctggtggtgg tatgtgtgcc aacgagaaag aattgcgtga aatcactgaa aatggtttga
    16201 aattgtcacc tgttacccaa tgtttgattg agcgttcgat tgccggtttc aaggaaattg
    16261 aatacgaagt gatgcgtgac tcagctgaca atgccttggt tgtttgtaac atggaaaact
    16321 ttgacccagt tgggattcac acaggggatt ccattgtatt tgcccctgcg caaaccatgt
    16381 cagactatga aaaccaaatg cttcgtgatg cgagcttgag cattattcgt gccctcaaga
    16441 ttgaaggtgg atgtaatgtt cagctagctc ttgatcctaa cagcttcaag tattatgtta
    16501 tcgaagtaaa ccctcgtgta tcacgttcgt cagcccttgc ttctaaagcg acaggatatc
    16561 cgattgctaa gttggctgcc aagattgcag taggtttgac cttggatgag gttataaacc
    16621 cagttacagg ttcaacctat gccatgtttg aaccagccct tgactacgta gttgctaaga
    16681 ttccacgttt cccatttgac aagtttgaaa agggtgaacg ccgtctcggt acacaaatga
    16741 aggcgactgg agaagtcatg gcaatcggtc gtaacatcga ggaatctctt ctcaaggcct
    16801 gccgctccct tgaaattggg gtgcaccaca atgaaatacc tgaacttgca gcagtttctg
    16861 atgatgcctt gattgaaaag gttgtcaaag cccaagatga ccgtctcttc tacgtatcag
    16921 aagcaattcg tcgtggctac acacctgaag aaattgcaga gcttacaaaa attgatatct
    16981 tctatcttga taaactcttg catatctttg aaattgagca agaattgggt gctcatccac
    17041 aagatctaga agttttgaaa acagccaaac ttaatggttt ttcagaccgt aagattgctg
    17101 aactctgggg aacgactgat gatcaagttc gccaacttcg cttggaaaac aagattgttc
    17161 cagtttataa gatggtagac acttgtgcgg cagagttcga ctccgaaacg ccatatttct
    17221 attcaaccta tggttgggaa aatgaatcta tcagatctga taaagaatct gtacttgtcc
    17281 taggttcagg tccaatccgt attggtcaag gggttgagtt tgactacgca accgttcact
    17341 ctgttaaggc tatccaggca gctggttatg aagctatcat catgaactca aacccagaga
    17401 ccgtttcaac agacttctct gtatcagata agctttactt tgagccattg acattcgaag
    17461 atgttatgaa cgtcattgac ttggaacaac caaagggagt tatcgttcag ttcggtggtc
    17521 aaacagccat caaccttgcg gagccattgg caaaagcagg tgtgaccatc cttggtacac
    17581 aggttgctga cctagatcgt gccgaagacc gtgacctctt cgagcaagct ctcaaagaat
    17641 tggatattcc acagccacca ggacaaacag ctaccaatga agaagaagca gctcttgcag
    17701 ctcgcaagat tggcttccca gttcttgtcc gcccatctta tgtacttggt ggacgtgcca
    17761 tggaaatcgt tgaaaacgaa gaagaccttc gttcttacat gcgaactgct gttaaggcta
    17821 gtccagacca cccagttctt gtcgactctt atatcgttgg gcaagagtgc gaagttgatg
    17881 ccatttcaga tggtaaaaat gtactcattc ctggtatcat ggagcatatc gaacgtgctg
    17941 gtgtccactc aggtgactca atggctgttt acccaccaca aaccttgtcg caaaaggttc
    18001 aggagaccat cgcagactac accaaacgct tagcaatcgg tcttcactgc cttggaatga
    18061 tgaacatcca gtttgttatc aaggatgaaa aagtctacgt tattgaggtc aatccacgtg
    18121 ccagccgtac tgttccattc ctatctaagg taaccaatat tcctatggct caagtagcga
    18181 ccaaactcat tcttggtcaa agtttatcag aacttggcta ccaaaatgga ctttaccctg
    18241 aaagcacccg tgttcatatc aaggcacctg tcttctcctt taccaaacta gctaaggtag
    18301 acagcttgct cggtcctgaa atgaagtcaa caggtgaagt tatgggttct gatgctactt
    18361 tggaaaaagc tctctataaa gcctttgaag cttcttatct acacttgcca acttttggta
    18421 atgtcgtctt taccatcgct gatgatgcca aagaagaagc cttgaacttg gctcgtcgtt
    18481 tccaaaacat tggttatgga atccttgcga cagaagggac agcagccttc tttgctagcc
    18541 atggcttgca agcccaacct gttggtaaga ttggtgatga cgataaggat atcccaagtt
    18601 ttgtacgcaa aggaagaatt caagctatca ttaacacagt aggaacaaaa cgaactgctg
    18661 acgaagatgg tgagcaaatt cgtcgttcag ccattgaaca cggggtgccc ctcttcacag
    18721 cgctagatac agctaatgcc atgcttaagg tacttgaaag tcgtagcttt gttacagaag
    18781 cgatttaaat agaaaaataa gatatagcag actg
//
LOCUS       DAVLIK010000036        18770 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLIK010000036 DAVLIK010000000
VERSION     DAVLIK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18770
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.036"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            131..868
                     /locus_tag="VXE87_001473"
     CDS             131..868
                     /locus_tag="VXE87_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0843000.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            865..2556
                     /locus_tag="VXE87_001474"
     CDS             865..2556
                     /locus_tag="VXE87_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0843001.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDARGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            2672..3235
                     /locus_tag="VXE87_001475"
     CDS             2672..3235
                     /locus_tag="VXE87_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0843002.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            3257..8746
                     /locus_tag="VXE87_001476"
     CDS             3257..8746
                     /locus_tag="VXE87_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0843003.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKSELQEQLRVAEQKQQADYSAKTWREFKIAELQAKEINNPTTPLPKQSEIDAAT
                     KALQDALQALAVDKTVLQNAINTANSKREEEYTAQTWKALKDALTAVNPVNEDETATQ
                     SKVDEATRNLEEAINNLVLLTEKPVLTFIETDKKALEREVVAKYSLENQNKTKIKSIT
                     ATLKKGETVVSTVELIGDDVTNETITSAFKNLEYYKEYTLSTTMVYDRGDGDVTEILD
                     NQPIQLDLKKVELKNIKRTDLIKYENGKETNESLITTVPDDKRNYYLKITSKNQKTTL
                     LAVKNIEETTVNGTPVYKVTAIADNLVSRTADNKFEEEYVHYIEKPKVHEDNVYYNFK
                     ELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKEFTGKLLSSEGKQFAITELEHPL
                     FNVITNATINNVNFENVEIERSGQDNIASLANTMKGSSVITNVKITGTLSGRNNVAGF
                     VNNMNDGTRIENVAFFGKLHSTSGNGSHTGGIAGTNYRGIVRKAYVDATITGNKTRAS
                     LLVPKVDYGLTLDHLIGTKALLTESVVKGKIDVSNPVEVGAIASKTWPVGTVSNSVSY
                     AKIIRGEELFGSNDVDDSDYASAHIKDLYAVEGYSSGNRSFRKSKTFTKLTKEQADAK
                     VTTFNITADKLESDLSPLAKLNEEKAYSSIQDYNAEYNQAYKNLEKLIPFYNKDYIVY
                     QGNKLNKEHHLNTKEVLSVTAMNNNEFITNLDEANKIIVHYADGTKDYFNLSSSSEGL
                     SNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILESVELQSQTMYQHLNRLGDYRVN
                     AIKDLYLEESFTDVKENLTNLITKLVQNEEHQLNDSPAARQMIRDKVEKNKAALLLGL
                     TYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIEIGSKENNIKGSRTFDAFGQ
                     VLAKYTKSGNLDAFLNYNRQLFTNIDNMNDWFIDATEDHVYIAERASEVEEIKNSKHR
                     AFDNLKRSHLRNTILPLLNIDKAHLYLISNYNAIAFGSAERLGKKSLEDIKDIVNKAA
                     DGYRNYYDFWYRLASDNVKQRLLRDAVIPIWEGYNAPGGWVEKYGRYNTDKVYTPLRE
                     FFGPMDKYYNYNGTGAYAAIYPNSDDIRTDVKYVHLEMVGEYGISVYTHETTHVNDRA
                     IYLGGFGHREGTDAEAYAQGMLQTPVTGSGFDEFGSLGINMVFKRKNDGNQWYITDPK
                     TLKTREDINRYMKGYNDTLTLLDEIEAESVISQQNKDLNSAWFKKIDREYRDNNKLNQ
                     WDKIRNLSQEEKNELNIQSVNDLVDQQLMTNRNPGNGIYKPEAISYNDQSPYVGVRMM
                     TGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYENGFLGYASNKYKQQSKTDGESVLSDE
                     YIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVNGSSVSSYDDLLTLFKEAVK
                     KDAETLKQEANGNKTVSMNNTVKLKEAVYKKLLQQTDSFKTSIFK"
     gene            8807..10528
                     /gene="pabB"
                     /locus_tag="VXE87_001477"
     CDS             8807..10528
                     /gene="pabB"
                     /locus_tag="VXE87_001477"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0843004.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADFLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELILEEN"
     gene            10529..11146
                     /locus_tag="VXE87_001478"
     CDS             10529..11146
                     /locus_tag="VXE87_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0843005.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            11196..11954
                     /locus_tag="VXE87_001479"
     CDS             11196..11954
                     /locus_tag="VXE87_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0843006.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAYSTWQGN
                     YYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNS
                     LFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            12081..13040
                     /locus_tag="VXE87_001480"
     CDS             12081..13040
                     /locus_tag="VXE87_001480"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0843007.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGNNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            13137..13976
                     /locus_tag="VXE87_001481"
     CDS             13137..13976
                     /locus_tag="VXE87_001481"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0843008.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(14024..14194)
                     /locus_tag="VXE87_001482"
     CDS             complement(14024..14194)
                     /locus_tag="VXE87_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0843009.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            14315..15199
                     /gene="miaA"
                     /locus_tag="VXE87_001483"
     CDS             14315..15199
                     /gene="miaA"
                     /locus_tag="VXE87_001483"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0843010.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            15192..16430
                     /gene="hflX"
                     /locus_tag="VXE87_001484"
     CDS             15192..16430
                     /gene="hflX"
                     /locus_tag="VXE87_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0843011.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     NYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            16423..17046
                     /locus_tag="VXE87_001485"
     CDS             16423..17046
                     /locus_tag="VXE87_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0843012.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            17061..17990
                     /locus_tag="VXE87_001486"
     CDS             17061..17990
                     /locus_tag="VXE87_001486"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0843013.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            18011..18766
                     /locus_tag="VXE87_001487"
     CDS             18011..18766
                     /locus_tag="VXE87_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0843014.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLVGETFNYK"
BASE COUNT         5990 a         3425 c         4096 g         5259 t
ORIGIN      
        1 gtactttgag aaacctgtgg ctatcttcct agtttacttt ttgattttta ttgagtataa
       61 gaggtctttc ctaagcagtt agaggagaat tttgctatac tgatactagt aagtggtaaa
      121 ggagcagagc atgacctaca caatcttaat cgtagaagat gaatatctgg taagacaagg
      181 tttgactaaa ctggtcaatg tagcagccta cgatatggaa atcatcggtc aggctgaaaa
      241 tggaaggcag gcttgggaat tgatccaaaa gcaggtgcca gatatcattt taaccgatat
      301 caacatgcct catctaaatg gcatccagtt ggccagtctg gtacgagaaa cctatcctca
      361 ggttcatttg gtctttttaa caggttacga tgattttgat tatgccttgt ctgctgtcaa
      421 actaggtgtg gacgactacc tgctcaaacc cttttctcgt caggatattg aggaaatgtt
      481 ggggaaaatc aaacaaaaac tagacaagga agagaaagaa gagcagttac aagatttatt
      541 gactaatagg tttgaaggaa acatggccca gaaaatccag tctcatctgg ctgatagcca
      601 atttagttta aagtctttag ccagtgactt aggttttagt ccgacctatc tgagttcctt
      661 gattaagaaa gagttgggct tgccttttca ggattatctg gtgagagaac gtgttaaaca
      721 agccaagctc ttgcttttaa ctacagatct gaagatttat gagatcgcag agaaggttgg
      781 ttttgaagat atgaactatt ttacccaacg ttttaagcag attgcaggtg tgacacctcg
      841 tcagtttaag aagggagaag accgatgaag cgttcttctc ttttagttag aatggttatt
      901 tccatctttc tggtctttct cattctccta gctctggttg gaactttcta ctatcaatca
      961 agttcttcag ccattgaggc caccattgag ggcaacagcc aaacgaccat cagccagact
     1021 agccacttta ttcagtctta tatcaaaaaa ctagaaacca cctcgactgg tttgacccag
     1081 cagacggatg ttctggccta tgctgagaat cccagtcaag acaaggtcga gggaatccga
     1141 gatttgtttt tgaccatctt gaagtcagat aaggacttga aaactgttgt gctggtgacc
     1201 aaatctggtc aggtcatttc tacagatgac agtgtgcaga tgaaaacttc ctctgatatg
     1261 atggctgagg attggtacca aaaggctatt catcagggag ctatgcctgt tttgactcca
     1321 gctcgtaaat cagatagtca gtgggtcatt tctgtcactc aagaacttgt tgatgcaagg
     1381 ggagccaatc ttggtgtgct tcgtttggat atttcttatg aaactctgga agcctatctc
     1441 aatcaactcc agttggggca gcagggcttt gccttcatta tcaatgaaaa ccatgaattt
     1501 gtctaccatc ctcaacacac agtttatagt tcgtctagca aaatggaggc tatgaaaccc
     1561 tacatcgaga caggtcaggg ttatactcct ggtcacaaat cctacgtcag tcaagagaag
     1621 attgcaggaa ctgattggac ggtacttggc gtgtcatcat tggaaaagtt agaccaggtt
     1681 cggagtcagc tcttgtggac cttgcttggg gccagtgtca catctcttct tgtttgtctc
     1741 tgcttagtgt ggttcagtct taaacgctgg attgctcctt tgaaggattt gagagaaacc
     1801 atgttggaaa ttgcttctgg tgctcaaaat cttcgtgcca aggaagttgg tgcctatgaa
     1861 ctgagagaag taactcgcca atttaatgcc atgttggatc agattgatca gttgatggta
     1921 gctattcgta gccaggaaga aacgacccgt cagtaccaac ttcaagccct ttcgagccag
     1981 attaatccac atttcctcta taacactttg gacaccatca tctggatggc tgaatttcat
     2041 gatagtcagc gagtggtgca ggtgaccaag tccttggcaa cctatttccg cttggcgctc
     2101 aatcaaggca aggacttgat ttgtctctct gacgaaatca atcatgtccg ccagtatctc
     2161 tttatccaga aacaacgcta tggagataag ctggaatacg aaattaatga aaatgttgcc
     2221 tttgataatt tagtcttacc caagctggtc ctacaacccc ttgtagaaaa tgctctttac
     2281 catggcatta aggaaaagga aggtcagggc catattaaac tttctgtcca gaaacaggat
     2341 tcgggattgg tcatccgtat tgaggatgat ggcgttggct tccaagatgc tggtgatagt
     2401 agtcaaagtc aactcaaacg tgggggagtt ggtcttcaaa atgtcgatca acggctcaaa
     2461 cttcattttg gagccaatta ccatatgaag attgattcta gaccccaaaa agggacgaaa
     2521 gttgaaatat atataaatag aatagaaact agctaactcc cagtcaattc tgggagtttt
     2581 atgcgtaatt gggcaaactt tctaggttgt ctatcttgct aaaaacaaga aaaaacggta
     2641 tgatagaaga gtgacaacag aggtaacaga gatgaacgag acacagattc aaagagaaac
     2701 acgtcaggta gtggaagatg ttttagaaaa gaccaatttg aagcaggggg ccctttttgt
     2761 tttaggtcta tcttctagtg aggtgctagg tggtcagatt gggaaagaat ccagtcaaga
     2821 gattggtgag ctgatagtgg agactatctt ggatattcta ggtagtagag gtatccattt
     2881 agcagttcaa ggttgtgagc atgtcaatcg ggctctcgtt gttgaacgtc aggtggcaga
     2941 gcagtttggt ctggaaattg tcagtgtcca tcctactctt catgcaggag gttcggggca
     3001 gttggcagcc tttaagttta tgcaggatcc agttgaggtt gaatttatca aggctcatgc
     3061 tggattggat atcggagaca ctgcaattgg catgcatgtc aagcatgttc aggttccgat
     3121 tcgccctatt ttgagagaga ttggtcatgc ccatgtaacg gcactggcta gtcgtccaaa
     3181 attaatcgga ggtgcgcgtg cgcactatcc gcaagatgct attagaaaga cctgagaatg
     3241 aataaaggag ataaaagtgt ttaaaaaaga ccgtttttca attcgtaaga ttaagggagt
     3301 tgtaggctct gtatttcttg gaagcctttt gatggctcct tctgtagtgg acgcagccac
     3361 ctatcactat gtaaataaag agattatttc acaagaagct aaagatttaa ttcagacagg
     3421 aaagcctgac aggaatgaag ttgtatatgg tttggtgtat caaaaagatc agttgcctca
     3481 aacagggaca gaagcatctg ttttgacagc ttttggttat ctatcaggtg acatcctcaa
     3541 aacgcttggc ttggacactg ttttagaaga aacctcagca aaacctggag aggtgactgt
     3601 agtcgaagtt gagactcctc aatcaacaac aaatcaggag caagctagga cagaaaacca
     3661 agtagtagag acagaggaag ctccaaaaga agaagcacct aaaacagaag aaagtccaaa
     3721 ggaagaacca aaatcggaga taaaacctac tgacgacacc cttcctaaag tagaagaggg
     3781 gaaagaagat tcagcagaac cagctccagt tgaagaagta ggtggagaag ttgagtcaaa
     3841 accagaggaa aaagtagcag ttaagccaga aagtcaacca tcagacaaac caacagagga
     3901 accaaaagtt gaacaagtag gtgaaccagt cgagccaagt gaagacgaac aggcaccaac
     3961 ggcaccagtt gagccagaaa agcaaccaga agctcctgaa gaagagaagg ctgtagagga
     4021 aacaccgaaa ccagaagata aaataaaggg tattggtact aaagaaccag ttgataaaag
     4081 tgagttaaat aatcaaattg ataaagctag ttcagtttct cctactgatt attctacagc
     4141 aagttacaat gatcttggac ctgttttaga aactgcaaaa ggtgtctatg cttcagagcc
     4201 tgtaaaacag cctgaggtaa atagtgagac aaataaactt aaaacggcta ttgacgctct
     4261 aaacgttgat aaaagtgaat tacaggaaca attaagagtt gctgaacaaa aacaacaagc
     4321 tgactatagc gctaaaactt ggagggaatt caaaattgct gaacttcaag ctaaagaaat
     4381 caacaaccca actacaccac ttcctaaaca aagtgaaata gatgcagcta ctaaggctct
     4441 tcaagacgct cttcaagctc ttgctgtaga taaaactgta ttacaaaacg ctattaacac
     4501 agctaatagc aaacgtgaag aagagtatac tgctcagaca tggaaagcgt taaaagatgc
     4561 tcttacagca gtgaatcctg ttaatgaaga tgaaactgca actcaaagca aagtagacga
     4621 agctactaga aacttagaag aagctatcaa taacctagtt ctattaactg aaaaaccggt
     4681 attaacattt attgagactg ataagaaagc attagaacgt gaagtagttg ctaagtattc
     4741 tctagaaaac caaaataaaa caaaaattaa atcaatcaca gctactctga aaaaaggaga
     4801 aacagttgtt agcactgtag agcttatagg cgatgatgta actaatgaaa ctataacctc
     4861 tgcatttaag aatctagagt actacaaaga atacacccta tctacaacta tggtttacga
     4921 tagaggtgac ggtgatgtaa cagaaatctt agataatcaa ccaatccaac tagatcttaa
     4981 aaaagttgag cttaaaaata ttaaacgtac agatttaatc aaatacgaaa atggaaaaga
     5041 aactaatgaa tcactaataa caactgttcc tgatgataag cggaattatt atttaaaaat
     5101 aacttcaaag aatcaaaaaa ctacattact agctgttaaa aatatagaag aaactacggt
     5161 taacggaaca cctgtatata aagttacagc aatcgcagac aatttagtct ctagaactgc
     5221 tgataataaa tttgaagaag aatacgttca ctatattgaa aaacctaaag tccacgaaga
     5281 taatgtatat tataacttca aagaattagt ggaggctatt caaaacgatc cttcaaaaga
     5341 atatcgtctg ggacaatcaa tgagcgctag aaatgttgtt cctaatggaa aatcatatat
     5401 cactaaagaa tttacaggaa aacttttaag ttctgaagga aaacaatttg ctatcactga
     5461 gttggaacat ccattattta atgtgataac aaacgcaacg ataaataatg tgaattttga
     5521 aaatgtagag atagaacgtt ctggtcaaga taatattgca tcattagcca atactatgaa
     5581 aggttcttca gttattacaa atgtcaaaat tacaggcaca ctttcaggtc gtaataatgt
     5641 tgctggattt gtaaataata tgaatgatgg aactcgtatt gaaaatgttg ctttctttgg
     5701 caaactacac tctacaagtg gaaatggctc tcatacaggg ggaattgcag gtacaaacta
     5761 tagaggaatt gttagaaaag catatgttga tgctactatt acaggaaaca aaacacgcgc
     5821 cagcttgtta gttcctaaag tagattatgg attaactcta gaccatctta ttggtacaaa
     5881 agctctccta actgagtcgg ttgtaaaagg taaaatagat gtttcaaatc cagtagaagt
     5941 tggagcaata gcaagtaaga cttggcctgt aggtacggta agtaattctg tcagctatgc
     6001 taagattatc cgtggagagg agttattcgg ctctaacgac gttgatgatt ctgattatgc
     6061 tagtgctcat ataaaagatt tatatgcggt agagggatat tcgtcaggta atagatcatt
     6121 taggaaatct aaaacattta ctaaattaac taaagaacaa gctgatgcta aagttactac
     6181 tttcaatatt actgctgata aattagaaag tgatctatct cctcttgcaa aacttaatga
     6241 agaaaaagcc tattctagta ttcaagatta taacgctgaa tataaccaag cctataaaaa
     6301 tcttgaaaaa ttaataccat tctacaataa agattatatt gtatatcaag gtaataaatt
     6361 aaataaagaa caccatctaa atactaaaga agttctttct gttaccgcga tgaacaacaa
     6421 tgagtttatc acaaacctag atgaagctaa taaaattatt gttcactatg cggacggtac
     6481 aaaagattac tttaacttgt cttctagcag tgaaggttta agtaatgtaa aagaatatac
     6541 tataactgac ttaggaatta aatatacacc taatatcgtt caaaaagata acactactct
     6601 tgttaatgat ataaaatcta ttttagaatc agtagagctt cagtctcaaa cgatgtatca
     6661 gcatctaaat cgattaggtg actatagagt taatgcaatc aaagatttat atttagaaga
     6721 aagcttcaca gatgttaaag aaaacttaac aaacctaatc acaaaattag ttcaaaacga
     6781 agaacatcaa ctaaatgatt ctccagctgc tcgtcaaatg attcgtgata aagtcgagaa
     6841 aaacaaagca gctttattac taggtttaac ttacctaaat cgttactatg gagttaaatt
     6901 tggtgatgtt aatattaaag aattaatgct attcaaacca gatttctatg gtgaaaaagt
     6961 tagcgtatta gacagattaa ttgaaatcgg ttctaaagag aacaacatta aaggttcacg
     7021 tacattcgac gcattcggtc aagtattggc taaatatact aaatcaggta atttagatgc
     7081 atttttaaat tataatagac aattgttcac aaatatagac aatatgaacg attggtttat
     7141 tgatgctaca gaagaccatg tctacatcgc agaacgcgct tctgaggtcg aagaaattaa
     7201 aaattctaaa catcgtgcat tcgataattt aaaacgaagt caccttagaa atactatact
     7261 cccactactg aatattgata aagcacatct ttatttaatt tcaaattata atgcaattgc
     7321 ctttggtagt gcagagcgat taggtaaaaa atcattagaa gatattaaag atatcgttaa
     7381 caaagctgca gatggttata gaaactatta tgatttctgg tatcgtctag cgtctgataa
     7441 cgttaaacaa cgactactaa gagatgctgt tattcctatt tgggaaggtt ataacgctcc
     7501 tggtggatgg gttgaaaaat atggccgcta taataccgac aaagtatata ctcctcttag
     7561 agaattcttt ggtcctatgg ataagtatta taattataat ggaacaggag cttatgctgc
     7621 tatatatcct aactctgatg atattagaac tgatgtaaaa tatgttcatt tagaaatggt
     7681 tggtgaatac ggtatttcag tttacacaca tgaaacaaca cacgtcaacg accgtgcgat
     7741 ttacttaggt ggctttggac accgtgaagg tactgatgct gaagcatatg ctcagggtat
     7801 gctacaaact cctgttactg gtagtggatt tgatgagttt ggttctttag gtattaatat
     7861 ggtatttaaa cgcaaaaatg atgggaatca gtggtatatt acagatccaa aaactctaaa
     7921 aacacgagaa gatattaata gatatatgaa gggttataat gacactttaa ctcttcttga
     7981 tgaaattgag gctgaatctg tgatttctca acaaaataaa gatttaaata gtgcatggtt
     8041 caaaaaaata gatagagaat accgtgataa caataaatta aatcaatggg ataaaattcg
     8101 aaatctaagt caagaagaga aaaatgaatt aaatattcaa tctgttaatg atttagttga
     8161 tcaacaatta atgactaatc gcaatccagg taatggtatc tataaacccg aagcaattag
     8221 ctataacgat caatcacctt atgtaggtgt tagaatgatg accggtatct acggaggtaa
     8281 tactagtaaa ggtgctcctg gagctgtttc attcaaacat aatgctttta gattatgggg
     8341 ttactacgga tacgaaaatg ggttcttagg ttatgcttca aataaatata aacaacaatc
     8401 taaaacagat ggtgagtctg ttctaagtga tgaatatatt atcaagaaaa tatctaacaa
     8461 tacatttaat actattgaag aatttaaaaa agcttacttc aaagaagtta aagataaagc
     8521 aacgaaagga ttaacaacat tcgaagtaaa tggttcttcc gtttcatcat acgatgattt
     8581 actgacattg tttaaagaag ctgttaaaaa agatgccgaa actcttaaac aagaagcaaa
     8641 cggtaataaa acagtatcta tgaataatac agttaaatta aaagaagctg tttataagaa
     8701 acttcttcaa caaacagata gctttaaaac ttcaatcttt aaataattga aatctctcat
     8761 ctgctttgcg gatgagggtt ttcttatttt atgctatact taaagtatgc atagaaaaac
     8821 agtgattgat tttaggactt tgggggagag atataccttt acccagccta ttaaagagtt
     8881 gaaaacgaga aatgtagaag aagtggcaga ttttctggca caagtggaaa gctaccaaga
     8941 gcaaggttat tatgtggtgg ggtatgtcag ctacgaggct gcacctgctt ttgaggaaaa
     9001 attagcagtt cacaaggatc ccctactggg agagtacctg ctttacttta ctgttcatga
     9061 tagcgtagaa acttccccta ttcctctgac ttatgaggat attgatttgc cctcaaattg
     9121 gcaggaagtg acgtctgcag cagactatga aaaggccatt gcccagatac accatcactt
     9181 gaggcaggga gacacctatc aggtcaacta caccgtccaa ctcaagcaaa agttaagtgc
     9241 caatcctttt gccatctaca atcgtatggt ggtagagcag gaggcgggct acaatgccta
     9301 tgtggaacat gacgagatgg cagtgatttc catgagccca gagctctttt ttgagcaaaa
     9361 tgatcgcgag ttgacaacac gaccaatgaa ggggacgact cagcgtgggg taactgacca
     9421 agaagatctt gaacaggcca gttggttgga acaggatccc aaaaatcgct ctgaaaatat
     9481 gatgattgtg gacctcttgc gcaatgatat gaaccgtatt tctgaagttg ggagcgagca
     9541 cgtggagcgt ctgtgccagg tagagcagta ttcaactgtt tggcagatga cttcgaccat
     9601 caagagtcag ttgcgagagg atgtggacct tgttgaaatc ttccgctcac tctttccttg
     9661 tggttccata acgggtgcac cgaaaattgc gacaatggag attatcaagg acttggagcc
     9721 tcaaccgcgt ggagtctact gtggaacgat tggtctcttg cttccaaatg gacgacggat
     9781 ttttaatgtg gccattcgta ccattcaact tcacaaaggt caagccattt atggagttgg
     9841 cggagggatt acttgggata gcacatggga atctgaatac cgagaggttc atcaaaaggc
     9901 agcagttctt tatcgtaaac aagctcgctt ccaactgatt acgacagggg aaatcagcca
     9961 gaagaacctg ctgtttgaag atcaacatct ggaaagactg agaaaagcta gtcgttattt
    10021 tgcttttcct tttgatgcag aagacttggg acacaagatt gaggaagagt gtcaggattg
    10081 tgaagctaat cgagattacc gcttgcgaat cagccttagc aaatctggag agatagaagt
    10141 caatcgtcaa gtattaaccc ctctcagtac aagcttttgt caggcccaag tctgccttca
    10201 ggaagctgct ttgaatcaat cctttaccta ctttaaaacc actcaccgac cgcatttgag
    10261 cctaggagaa caagagaaga tttaccacaa taagtcagga gaactgcttg aaacctctat
    10321 aggaaatttg gttctgaaaa tcgctggaaa actctacaca ccgcctatcc gacttggaat
    10381 cttgccagga atttaccgtc agtatttgct agaaacagga caggtagaag agaaagtctt
    10441 gaccttggca gatttagccc aagcagaagc tatttacggc tgtaatgcag tgagaggctt
    10501 gtatgaacta atccttgagg agaactagat gaaactgata tttttgcatg ggttagggca
    10561 gtcagcagag tcttggaaag aagttcggaa tctactgaca gattatcctt ctgaggctat
    10621 cgagttattt ccttctggag ttagtaacta tcaacaagct aaggagcgag tttatcagca
    10681 cctagctcaa gagacagaac cttttgtttt gattggattg tccttaggtg ctgccctggc
    10741 actagaactt tccagttacg atttaccaaa tcttcgagct ttgattctgt caggatgccc
    10801 gcttaaatta gcagggaata tcctatttta tcttcagttg ctgattttta aactacttcc
    10861 caaaagagta tttgaaaaac agggagcaga caaggctctt atggtcggag tttctgagga
    10921 gttgaagaca cttgatttaa cggatatagc aggaacttgc ccttatccaa ccttactaat
    10981 ttgtggtatc aaagataaac cgaatcttag ttctatgaga agtcttcata aactaatatc
    11041 agaatcccaa tttcagatta tcccagatgg ccctcatgtc ttgaataagg caaaaccaaa
    11101 ggagtttgta gaaaagacca gaagttttct tgaattgctg aaataagttt gataaaataa
    11161 tattgaaatc gatatcataa ttatgggaga aagaaatgaa taaacgtcta tttttaaaaa
    11221 tgagtctggt gacgttgcca attttagcct tgttttcaca acctgtgtta gcagaggaaa
    11281 acattcattt ttcgagttgt aaggaagctt gggctaatgg atattcggat cttcatgagg
    11341 gagaacctgg ttattctgcc aagttagacc gcgatcatga tggtgtggct tgcgaattga
    11401 aaaatgctcc taagggtgct tttaaagcaa aacaagcggc tacaactcaa actgatacaa
    11461 cttcatccac agcaagtggt tgggttaagc aggacggttc ttggtactat tttgatggaa
    11521 atggaaatct agtgaaaaat gcatggcagg gaaattatta cctgaaagct gatggtaaaa
    11581 tggcacagag tgaatggatt tatgactctt cttatcaagc ttggtattat ttgacatcag
    11641 atggttctta tgcttacagt acatggcaag gaaattacta tctaaaatcg gatggtaaaa
    11701 tggctgtcaa tgaatgggtt gatggtggac gttattatgt tggcgctgac ggagtttgga
    11761 aggaaggtca agcaagtaca gcttcttcta gtaatgatag caatagtgaa tattctgctg
    11821 ctttaggaaa ggcaaaaagt tataattcgt tattccacat gtcaaaaaaa cgtatgtata
    11881 gacaattaac ttctgatttt gataaatttt caaatgatgc agctcaatat gccattgatc
    11941 atttagatga ttaacagata ctggtaggcg aaaaaattcc ttataattca tttacgcaaa
    12001 cctttgcata agtgaatgta ttttgatata ctagtactgt aagcattttc aattactaca
    12061 caatgaaaaa ggagaatatg atgagtcaaa agattattgg gattgacctt ggtggaactt
    12121 ctatcaaatt tgcaatctta acaacagcag gagaaatcca aggaaaatgg tcaatcaaga
    12181 ccaacatttt ggatgaggga agtcatatcg ttgatgatat gattgagtct attcaacatc
    12241 gtttggactt gcttggattg gcagcagcgg acttccaagg cattggaatg ggatcaccag
    12301 gtgtggttga ccgtgacaaa gggactgtta tcggtgccta caacttgaac tggaaaaccc
    12361 ttcaaccaat caaacaaaag attgaaaaag ctttgggcat tccatttttc atcgataatg
    12421 atgccaacgt agcagctctt ggtgagcgct ggatgggtgc tggaaataac caaccagacg
    12481 ttgtctttat gacactcggt actggtgttg gtggtggtat tgtcgcagaa ggcaaattgc
    12541 ttcacggtgt tgctggtgca gcaggtgagc ttggtcatat cactgttgat tttgaccaac
    12601 caattgcatg tacttgtggt aaaaaaggct gccttgagac agttgcttca gcaacaggga
    12661 ttgtcaactt gactcgtcgc tatgccgatg aatacgaagg cgatgcagcc ttgaaacgct
    12721 tgattgataa tggagaagaa gtaactgcta agactgtctt tgatctcgca aaagaaggag
    12781 acgaccttgc tttgattgtt taccgtaact tctcacgtta cttgggaatc gcttgtgcta
    12841 acattggttc aatcctaaac ccatcaacaa tcgtcatcgg tggtggtgtg tcagctgcgg
    12901 gagaattcct tctacaaggt gttcaaaaag tttacgatga aaatagtttc ccacaagtac
    12961 gcacatctac taaattagct cttgcaactc taggaaatga cgctggagtt atcggagcag
    13021 catcacttgt attgcaataa gataatgaga gaggaaaatg ctaacctaga gttagtaatg
    13081 ttcctctttt attttttatg ctatactagt taggacaatg aatgaggtga aacgaaatga
    13141 caaaagcaga tacgattttt aaagagaata ttgaacgcat tctaaaggaa ggtgttttct
    13201 cagagcaggc tcgtcctaag tacaaggatg ggactgttgc taattccaag tatgtaactg
    13261 gtgccttttc cgagtacgac ttatctaaag gagaatttcc tatcacaacc ttgcgtccca
    13321 ttgcaatcaa atccgccatc aaagaagttc tctggattta ccaagaccag tcaaatagct
    13381 tagaagtgct taatgacaag tacaatgttc actactggaa tgactgggaa gttggagaca
    13441 cgggaaccat tggtgagcgc tatggtgccg ttgttaagaa acacgacatt atcaataagc
    13501 ttctcaaaca gttggaaacc aatccttgga accgccgcaa tattatttcg ctctgggatt
    13561 accaagcttt cgaagaaaca gatgggctgc tcccgtgcgc ctttcagacc atgtttgatg
    13621 tccggcgtgt tgatggggaa atctatctgg atgcgacctt gacccagcgc tccaatgata
    13681 tgctggtggc ccaccacatc aacgctatgc agtatgtggc tttgcagatg atgattgcca
    13741 aacattttgg ctggaaggtt gggaagttct tctacttcat caacaacctc catatctatg
    13801 ataatcaatt tgaacaagct caggaattgc tccgtcggga gccgtcaaac tgccaaccac
    13861 gcttggtttt aaatgttcct gatgggacta atttctttga tatcaaagca gaagattttg
    13921 agttggtgga ttatgaccct gttaagccac agttgaagtt tgacctagct atttaaaaga
    13981 atagaaaaaa gaagttgaga ataatcccaa cttcttttgt ttcttaacgt gatacgcggc
    14041 gacgagctgc ttttttacgg ttttcttcga tgaaagctgc tttttgctct tctggttcga
    14101 ttactttctt tttaaatgcg tatactgcac ctgcaacggc agcgacagtt cctgcgacac
    14161 ctgttacaag acctttagcg aatcctttag ccatgagtct tcctccttta tattctcaat
    14221 cagccagcct cctcaagagg tcacattttt ctgactgacc tttttgtgtt ataataatag
    14281 taacgaaaaa atgggaattt ttcaaggaaa aaagatgaaa acaaaaataa ttgtgattgt
    14341 tggaccgact gctgttggaa agacggctct agctattgaa gttgcaaagc gttttaatgg
    14401 cgaagtggtt agtggagata gccagcaagt ctatcgagga cttgatattg ggacggccaa
    14461 ggctagtcca gaagagcagg cagctgttcc tcatcattta atcgatgtta gagagataac
    14521 cgagtcttac tcggcttttg attttgtttc agaagctaag atgactattg aggatattca
    14581 cagccgtggc aagctagcca ttatcgccgg tgggactgga ctttatatcc agagcttgct
    14641 agaaggttac cacctaggtg gggagactcc tcatgaggag attttagctt atcgagctag
    14701 tttggagcca tattcagatg aggaattagc ccatttggtg gagcaagcag gccttgagat
    14761 tccccagttt aatcgtcgtc gtgctatgcg tgccttagaa attgcccatt ttggtcagga
    14821 tttggaaaat caagagacct tgtatgaacc gctgattatc tgcttggatg atgaacgtag
    14881 tcaactttat gagcgtatca accaccgagt ggatttgatg tttgaggctg ggcttttgga
    14941 tgaggccaag tggctgtttg accattcccc taatgtacag gctgctaaag gaattggcta
    15001 taaggaactc tttccttatt tccgtggaga gcagaccttg gaggaagcta gtgagagtct
    15061 caaacaggct actcgtcgtt ttgccaagcg tcagctgacc tggttccgta atcgcatgca
    15121 ggtcaccttt tatcagattg gagaatctgg tgtacaagac cgcattttaa gccagataga
    15181 ggagttttta gatgattgaa acggagaaaa aagaggagcg agtcctgctg attggtgtgg
    15241 aattgcaggg tatggacagt tttgacctct ccatggaaga attggctagt ttagcgaaaa
    15301 cggcaggggc agtcgttgta gataactaca gacaaaaacg tgaaaaatat gattccaaga
    15361 ccttcgtcgg ctctggtaag ttggaagaga ttgcgcttat ggtggatgca gaagaaatca
    15421 ctactgtcat cgtcaacaac cgtctgacac caaggcagaa tgtcaatcta gaggaagttc
    15481 tcggtgttaa ggtcattgac cgtatgcagt tgattttgga tatctttgcc atgcgggctc
    15541 gaagccatga agggaagctc caagtccacc tagcccaact caaatacctc ttgcctcgct
    15601 tggttggtca ggggattatg ctcagccgtc aggcaggggg aattggttcc cgtggtcctg
    15661 gtgaaagcca actggagctg aaccgtcgta gcgttcgcaa tcaaatcacg gatatcgagc
    15721 gccagctcaa ggtggttgag aaaaatcggg cgactgtcag agaaaaacgt ttggagtcta
    15781 gcacctttaa gattggtttg attggttata ccaatgctgg gaaatcaact atcatgaaca
    15841 tcttgaccag taagacccag tatgaagcag atgagctctt tgcgactctg gatgcgacaa
    15901 ccaagagtat tcatctggga ggcaatctcc aagtaacttt gacagatacc gttggcttta
    15961 tccaagattt gccgacagag ttggtgtcca gtttcaagtc aaccttggaa gaaagcaagc
    16021 atgtggacct tctggttcat gttatcgatg ctagcaatcc ttatcacgag gagcatgaaa
    16081 aaacggttct ctccatcatg aaagacctgg acatggaaga tattcctcac ttgacgcttt
    16141 ataataaagc ggatttggtg gaggatttca cgcctaccca aacgccatat accctcattt
    16201 ctgccaagtc tgaggacagt cgtgaaaact tgcaagcatt attgctagat aagattaagg
    16261 aaatttttga agcatttacc ctgcgagtgc ctttttcaaa gtcctacaag attcatgatt
    16321 tagagagtgt tgcaattctg gaagaacgtg attatcagga agacagcgaa gtgattacag
    16381 gctacatttc cgaaaaaaat aaatggaggt tagaagaatt ttatgactga tattaaagct
    16441 ttggctctaa agtatggagg ttatacaagt ctggacaagg tctatctgga tcagcttcta
    16501 gctggtaaaa cagagcagga gcagttaaca cttattacac ctccgccaag tgttgttaat
    16561 gcctactttg cagaactcta tcagaaaaag agtcctcagg ctgcgacgga ttattttgca
    16621 gaactcagtc aggaactgaa tctttacaat actgagccaa gtttcaccct agaaaataag
    16681 ccttttattc ggcttaatct gtctggtaaa tcctttggtt tttgttatga tagtgacggc
    16741 cttggtcgga ttttctctga aaatgaggag aaaatctcgg atgacttgct ctttgaaatt
    16801 gcgcaaattt tcccccatca attagtcttt gaagagtctg gtaagattta catgaagcct
    16861 gtcgaggacg aggaagttgt cagcctagaa agtctcacag ctttgactga tttggaaaga
    16921 ttggctgatg gtcgaaaacg tctcaaaggc tacagccaag aggatttatt gcaagaagct
    16981 gctgcttttt ctggcaaacg ctatttccga tcggaaaacc gcacagccat gttatatatt
    17041 gattaattag aaagtatcga atggatattc aatttttagg aacgggggct ggtcagccct
    17101 ctaaagctcg caacgtttca agtctcgccc tgaaactttt ggatgagatt aacgaagttt
    17161 ggctctttga ctgtggagaa ggtacgcaaa atcgcattct ggaaaccaca attcgaccac
    17221 gtaagatcag caaaatcttt attacccatc tgcatggaga ccacattttt ggtttgccag
    17281 gtttcctttc tagccgtgcc tttcaggcca atgaagagca gacagatttg gaaatctacg
    17341 gacctcaagg aatcaagtca tttgtcttaa ccagccttcg tgtgtcaggt tctcgtctgc
    17401 cctaccgcat tcatttccat gagtttgacc aagattctct gggtaaaatt cttgaaaccg
    17461 ataaattcac tgtgtatgca gaggagctgg atcacactat tttctgtgtt ggctatcgtg
    17521 tcatgcaaaa agatctagaa gggacgctgg atgctgaaaa actcaaggct gctggtgttc
    17581 cgttcggccc gctttttggt aaaatcaaaa acggccagga tcttgttttg gaagacggaa
    17641 ctgaaatcaa ggcagcagac tatatctcag cgccacgtcc aggtaagatt atcactattt
    17701 taggagacac tcgaaaaacg gatgccagtg tgcgtctggc tgtcaatgca gatgtcctag
    17761 ttcatgagtc cacttatggc aagggtgatg aaaaaattgc tcgtaaccat ggtcactcaa
    17821 ctaatatgca agctgcacaa gtagcggtag aagcaggtgc caaacgcctc ctactcaacc
    17881 atatcagtgc ccgtttcctc tcaaaagata ttagcaaact caagaaagac gctgccacaa
    17941 tttttgaaaa tgtccatgtg gtcaaagact tggaagaagt ggaaatctag cagtcacaga
    18001 aaggataagt atgcctacta ttctcattac cggagctagc ggtggtctag ctcaagaaat
    18061 ggtcaaactc ctgcccaatg accaactcat cttgcttggt agaaataagg aaaaattagc
    18121 ccaactctac ggaaattatt cccatgcaga attgattgaa attgatatta ccgacgattc
    18181 agccctagaa gctctggtaa ctgatcttta tctccgctat ggcaagattg atgtcttgat
    18241 taacaacgct ggttacggga tttttgaggg atttgaccag attgctgata aagatattca
    18301 ccagatgttt gaggtcaata cctttgccct gatgaatctg tctcgtcacc ttgcggctcg
    18361 tatgaaggaa agcagcaaag ggcatatcat caacatcgtc agcatggcag gtctaatagc
    18421 tactggcaag tctagtcttt actcagcgac caagtttgcg gctattggtt tttcaaatgc
    18481 tctgcgactc gaacttatgc cctatggagt ctatgtgaca acagtcaatc caggtccaat
    18541 ccgaacagga ttttttgacc aagctgaccc agatggaact tatcttaaat cggttgaccg
    18601 cttcctctta gaggcagatg cagtggctaa aaagattgtc aagattatag gcaaaaataa
    18661 acgagaactc aatctcccga ttttgttgaa cctagcccat aagttttata ctctctttcc
    18721 caagctagct gataagttgg taggggaaac ttttaattat aagtaaaaag
//
LOCUS       DAVLIK010000037        18343 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLIK010000037 DAVLIK010000000
VERSION     DAVLIK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18343
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.037"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..288
                     /locus_tag="VXE87_001488"
     CDS             <1..288
                     /locus_tag="VXE87_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0843015.1"
                     /translation="VVLAGVVVRAVKDYLVQKGGEKTIKIVEILAKNAVNAVEQVAAE
                     TGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQMNDAWKGQE"
     gene            288..1244
                     /locus_tag="VXE87_001489"
     CDS             288..1244
                     /locus_tag="VXE87_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0843016.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGFYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGSMADKPEFTVEPDGLITVK"
     gene            complement(1497..2465)
                     /locus_tag="VXE87_001490"
     CDS             complement(1497..2465)
                     /locus_tag="VXE87_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0843017.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            2601..3458
                     /locus_tag="VXE87_001491"
     CDS             2601..3458
                     /locus_tag="VXE87_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0843018.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            3445..4224
                     /locus_tag="VXE87_001492"
     CDS             3445..4224
                     /locus_tag="VXE87_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843019.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTANLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            4248..5600
                     /locus_tag="VXE87_001493"
     CDS             4248..5600
                     /locus_tag="VXE87_001493"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0843020.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSVIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            5674..6048
                     /locus_tag="VXE87_001494"
     CDS             5674..6048
                     /locus_tag="VXE87_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0843021.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            6050..6898
                     /locus_tag="VXE87_001495"
     CDS             6050..6898
                     /locus_tag="VXE87_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0843022.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            7164..7931
                     /locus_tag="VXE87_001496"
     CDS             7164..7931
                     /locus_tag="VXE87_001496"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0843023.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWIDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            7943..9127
                     /locus_tag="VXE87_001497"
     CDS             7943..9127
                     /locus_tag="VXE87_001497"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0843024.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNLQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            9124..10995
                     /locus_tag="VXE87_001498"
     CDS             9124..10995
                     /locus_tag="VXE87_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0843025.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLESTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(11138..12322)
                     /gene="mntE"
                     /locus_tag="VXE87_001499"
     CDS             complement(11138..12322)
                     /gene="mntE"
                     /locus_tag="VXE87_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0843026.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            12626..15322
                     /locus_tag="VXE87_001500"
     CDS             12626..15322
                     /locus_tag="VXE87_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0843027.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            15335..16126
                     /gene="yghU"
                     /locus_tag="VXE87_001501"
     CDS             15335..16126
                     /gene="yghU"
                     /locus_tag="VXE87_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0843028.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTVGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            16242..16652
                     /locus_tag="VXE87_001502"
     CDS             16242..16652
                     /locus_tag="VXE87_001502"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0843029.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANHDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            16664..18259
                     /locus_tag="VXE87_001503"
     CDS             16664..18259
                     /locus_tag="VXE87_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843030.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
BASE COUNT         5299 a         3537 c         4289 g         5218 t
ORIGIN      
        1 gtcgttttgg caggggttgt agttagggca gtcaaggact acctggttca aaaaggtgga
       61 gaaaagacca tcaagattgt tgaaatcttg gccaaaaatg cagtaaatgc cgtggagcag
      121 gtagctgctg aaactggcta caagggagat gaaaaactgg cacaggctcg cgctaaaatt
      181 cgtgctgagc ttacaaaata caatattagc atgactgaca aagacttaga caccttcgta
      241 gagtcagcag tgaaacagat gaacgacgct tggaaaggac aagagtaatg gatatcgata
      301 caagcagact acgaacaggc ttgccccagg ttggggtgca gccttatcga caagtacatg
      361 cccactcaac aggcaaccgt aactcaaccg ctcaaaatga agcggattat cactggcgga
      421 aagacccaga attaggtttt ttctcgcacg ttgttgggaa cggtcgcatc atgcaagtag
      481 gtcctgtgaa caacggaagt tgggatgttg ggggcggttg gaatgctgag agttatgcag
      541 cggttgaact gattgaaagc cattcaacta aggaagagtt tatggctgac tatcgcctct
      601 atatcgaatt gctacgcaat ctagcggacg aagcaggctt gccgaagact cttgatacag
      661 acgacttggc aggtatcaag acgcatgaat actgtaccaa taaccaacca aacaaccact
      721 cagaccatgt ggatccatat ccatatcttg caagttgggg cattagccgt gaacagttta
      781 agcaagacat cgaaaacggc ttgagcgctg caacaggctg gcagaaaaat ggcactggct
      841 actggtacgt acactcagac ggcttttatc caaaagataa gtttgagaaa atcaacggta
      901 cctggtatta tttcgatggc tcaggctata tgctttcaga ccgctggaag aagcacacag
      961 acggtaattg gtactggttc gacaactcag gcgaaatggc tacaggctgg aagaaaatcg
     1021 ctgagaagtg gtactatttt gatgtagaag gtgccatgaa gacaggctgg gtcaagtaca
     1081 aggacacctg gtactactta gacgctaaag aaggcgccat ggtatcaaat gcctttatcc
     1141 agtcagcgga cggaacaggc tggtactacc tcaaaccaga cggtagcatg gcagacaagc
     1201 cagagttcac agtagagcca gatggcttga ttacagttaa ataaatagaa aggaaacttt
     1261 ctaaattgtt ctttcaccgc aggctcaggc ttgcggtttt tttgtttgct caaaaggggc
     1321 aaaaaagggg caaaagtgtc gtaaatctct gtaaaatgat gtaaaaacat ttatttaaaa
     1381 gctcaaaata tagctgtttt aaaaggtatt gtaagatata gtaaaacgat gtaaaggtat
     1441 ttttaaatgc ggatgaatta taaaaccacg aattctatgt gactcgtggt tcttttttat
     1501 aaactagtag agtgttttgg ttgtactttt tgttcagggt caatgtagtt gatagcgttg
     1561 ttgacagcag ttggagcttc tccgaggcct gtcgcaatca gatcaatttt tccgtcatag
     1621 tagcagcagt caccgatagc atagatacct gcttggctgg attcctgttt gctgttgacg
     1681 ataatcttgt gacggttgag gtcgagcccc cagtttttaa ggttaccgac agaagatttg
     1741 aaaccatagt tgacaaagag gtggtctagg tcaatggttt cagtttcatc agatttgact
     1801 tttgtgattt caagtttatc aagtgttttt ccatttccaa ggagttggct aggggcgaat
     1861 ggtgtcttga tggttacaga tgattcttgc aaggcttgaa cactgtgttc caaggcacgg
     1921 aaattatctc tgcggtgaac aagggtagtt ggtgcgattt tttcaaaagc caaagcccaa
     1981 tccacagccg agtctccccc accaagaatc gtcactttct taccagcgta ttgctgaatg
     2041 ttagaaacgt ggtagtggat attttcatag ccctcaaccc cttcaagttc cagcggacgt
     2101 ggtttgaagg caccgccacc catagcgatg ataactgttt tagtcaggtg acttccttta
     2161 gaagttgtga tggcaaattc ttcttcttgt ttgtcaatct caagaaccgt ttcattgaga
     2221 tgaatagggg tatcaaatcc atttagctgt tcaatcaagc ggttagtcaa ctcttctcca
     2281 gtcaggtttg ggaagcctgg tacgtctagg atttcctttt cagggtagag aatagcaggt
     2341 tgtccaccta gctggggaag agagtcgatg atttgaacct tggcttggcg taggtgggca
     2401 taaaaggctg caaaaagccc gacaggacca ccacccacaa tggtaatatc atagagttga
     2461 gacatagttt ctcctttgtt ttttctagtc agtttatttt atcatatttt tgttcaatgt
     2521 aaaatggact aggataggga aaaaaatgcc agaaaatggt ataataggac gaaagtgttt
     2581 tgatagggag gatatcaggg atgaattttc aacaattatc caatctgcaa tattggacca
     2641 gtttgtttgc aagtccatgg acgatagcta tcaatctgat tgatattttg attgttgctt
     2701 atattttata ccattttaca aaagctattg caggaaccaa gattatgatt ttggtacgtg
     2761 gagttttggt gtttatttta gctcaaatcc ttgcaaatat gattggtttg actacgattt
     2821 cttggttaat caatcaaatt attacttatg gggttattgc ggcggttgtt atcttctctc
     2881 cagagattcg gactggtttg gaacgtttgg gaagagcgac agattttttt tccaatgccc
     2941 ctattagtgc tgaggaacag atgattcgtg cctttgttaa gtctgttgaa tacatgagtc
     3001 ctcgtaaaat cggggccttg gttgctattc agcgtgtacg taccttgcag gagtatattt
     3061 cgacaggaat tcccttggat gctaagattt ctgcagaact tctcattaac atttttattc
     3121 ccaacactcc cctacatgat ggtgcggtga ttatcaaaga agaacgtatc gctgtgacgt
     3181 ctgcctatct gcccttgaca aaaaacacag ggatttccaa ggaatttggg accagacacc
     3241 gggcggctat cggtttatca gaagtctcag atgccttgac ttttgtcgta tcagaggaaa
     3301 cgggaggaat ttcgataacc tataatggaa ggtttaagca caacctaaca cttgatgaat
     3361 ttgaaacaga attacgtgaa atcttacttc caaaagagga agtgggtctt agttttaaag
     3421 aacgattgct aggaggatgg aaacatgaaa aaaaatagtt tatatatcat atcctcactc
     3481 ttttttgctt gtgtcttatt tgtctatgct acggcgacga attttcaaaa cagtaccagt
     3541 gctaggcagg taaaaacgga aacctatact aatacagtaa caaatgtccc tattgacata
     3601 cgctataata gtgataagta ttttattagc ggttttgctt cagaagtatc agtggtcttg
     3661 actggggcaa atcgcctatc gctagctagt gaaatgcaag aaagtacacg taaattcaag
     3721 gttactgcta acctaacaga tgccggtgtt ggaacgattg aagttccttt gagcattgaa
     3781 gatttaccca atgggctgac cgctgtggcg actccgcaaa aaattacagt caagattggt
     3841 aagaaggctc agaaggataa ggtaaagatt gtaccagaga ttgaccctag tcaaattgat
     3901 agtcgggtac aaattgaaaa tgtcatggtg tcagataaag aagtgtctat tacgagtgac
     3961 caagagacat tggatagaat tgataagatt atcgctgtct tgccaactag cgaacgcata
     4021 acaggtaatt acagtggttc agtacctttg caggcaatcg accgcaatgg tgttgtctta
     4081 ccggcagtta tcactccgtt tgatacaata atgaaggtga ctacaaaacc agtagcacca
     4141 agttcaagca catcaaattc aagtacaagc agttcatcgg agacatcttc gtcaacgaaa
     4201 gcaactagtt caaaaacgaa ttaaaaatag aaaaggattt tataacaatg ggtaaatatt
     4261 ttgggactga tggagtccgt ggagaagcta acctagaact aacaccagaa ttagccttta
     4321 aactaggacg ttttggaggc tatgttctta gtcaacatga aacggaagcg ccgaaagtct
     4381 ttgtaggacg tgacacacgt atttcagggg aaatgttgga atcggccttg gtggcaggtc
     4441 tcctttcagt agggattcac gtatacaaac ttggtgtcct tgcaacacca gcagtagctt
     4501 acttggttga aactgaagga gcaagtgccg gtgtcatgat ttctgctagc cacaacccag
     4561 cccttgataa cggaatcaag ttctttggcg gtgatggctt caaactagat gatgaaaaag
     4621 aagcagaaat tgaagccttg ctagatgctg aggaagacac tcttcctcgt ccaagtgcag
     4681 aaggcttagg aattttggta gattatccag aaggcttgcg taagtatgaa ggataccttg
     4741 tttcaactgg aactcctctt gatggaatga aggttgcctt ggatacagct aatggagcag
     4801 cttctaccag tgcccgtcaa atctttgcag accttggtgc ccaattgacg gttatcgggg
     4861 aaacaccaga cggtcttaac atcaacctta atgttggttc aacacatcca gaagcccttc
     4921 aagaagtggt caaagaaagt gggtcagtta ttggtttggc ctttgatgga gacagtgacc
     4981 gcttgattgc tgttgatgag aatggtgaca tcgtcgatgg tgacaagatt atgtacatca
     5041 tcggaaaata cctttctgaa aaaggacaat tggctcaaaa tacaattgtg acaactgtta
     5101 tgtctaacct tggtttccac aaggccttga atcgcgaagg tattaacaag gcagttactg
     5161 cagttggtga ccgctacgtt gttgaagaaa tgagaaaatc aggttacaac cttggtggtg
     5221 aacagtctgg tcacgttatc ttgatggatt acaataccac aggtgatggt caattatcag
     5281 cagttcaatt gactaaaatc atgaaggaaa ctggtaagag cttatcagag ttggcggcag
     5341 aagtaacgat ttatccacaa aaattagtta atatccgagt ggaaaacgtc atgaaggaaa
     5401 aggccatgga agtgccagct atcaaggcca tcatcgagaa gatggaagaa gaaatggcgg
     5461 ggaacggccg tatccttgtt cgtccaagtg gaacagagcc cctcttgcgt gttatggcag
     5521 aagcgcctac aacagaagaa gtggactact atgttgatac tatcacagat gtagttcgtg
     5581 ctgaaattgg gattgactaa atcctagaaa actagatgaa aataaaaaat tatggtacaa
     5641 tagcttataa tattgtagcc gatggagaaa gacatgaatc ttaaacgtga acaagaattt
     5701 gttagtcagt atcattttga tgcacgtaat tttgaatggg aaaatgaaaa tggagctcct
     5761 gaaaccaagg tggatgtgaa tttccaattg ctccaacatg accaagaaaa tcaagtgact
     5821 tccttgattg tcatcttgag ctttatgatt gtatttgata agtttgtcat tagtggaaca
     5881 atctcacaag taaaccatat cgatggccgt attgtcaatg aaccaagtga attgaaccaa
     5941 gaagaggtgg aaaccttggc tcgtccatgt ttgaacatgc tcaatcgttt gacttacgaa
     6001 gtgactgaaa ttgcattaga cttaccagga attaatttgg agttctaata tgaaattagc
     6061 tgttttcaca gattcctctg cttatctcag tgcagagatc ttgcaaagag aagacttgtt
     6121 tgtcttggat attcctgtca atattgatgg tgaggaatat gtcgaaggca tcaatctgtc
     6181 tgctgaggaa ttttaccaaa aaatggctca ggcttctgaa ttgcctaaga ccagtcaacc
     6241 aagtattgcc aagttagatg aaatcttaac ttcgctcaaa gaacaaggtt atacacatgc
     6301 cttggggctt ttcctatctt ctggaatttc aggtttttac caaaatatcc agtatatggt
     6361 cgatgactat gagggcttaa ccattgcttt cccagacact ttgattacaa gtgctcccct
     6421 aggcatcatg gttgaaagcg tctttaattg gcgtgatcag ggcgatgatt ttgccagcat
     6481 tcaggataag ctagccattc aaatcagccg tacgtcagcc tttatcatgg tagatgactt
     6541 ggatcatttg gtaaaaggtg gacgcctttc aaatggggct gccattttgg gcaatttgct
     6601 tagcattaag ccaatccttt attttaacga tcaaggtgtg attgaagttt acgaaaaagt
     6661 tcgtactgaa aagaaggcca ccaaacgctt aattgaaatt atcaaggaaa caacggcttc
     6721 aggtcaatac cgggtcattg tcattcatgg gaatgctcct gaaaaggctg aagaattgcg
     6781 tcagcatttg cttgattttg gcttgggttc ggatgtttca cttgctacat ttggtagtgt
     6841 cattggaacg cacctaggag caggaagtat tgctctaggt tatattccag tgatttagtt
     6901 ggcacttcta ggctagttaa tcttagaaat tgaacacgga ctacctgcct cttgaaaaaa
     6961 gatgcctgtc ttgcctttcg tggaaagtca gtgccattcc ctatttttca ggggcagcta
     7021 aggtcctttg tatcttgata attgaacacg cctggaaccc tgtgtgaaaa agatagttct
     7081 tccaagaagt agacacttct tgatcagaat tcctattttc actttgtgtt cttacaggct
     7141 ttgtatcttg gacaggagta gagatgagta ttcgagtaat tattgccggt tttaagggaa
     7201 agatgggcca ggctgcttgt cagatggtat tgactgatcc agacttggac ttggtagcag
     7261 ttttggatcc ttttgagtct gagtcagaat ggcagggtat tcctgttttc aaggataagg
     7321 ctgatttagc tggttttgaa gcggatgtct ggatagattt tactactcca gctgttgcct
     7381 acgaaaatac acgttttgct cttgaaaatg gctttgctcc agtagttgga acgactggtt
     7441 tcacgagtga agaaattgca gagctaaaag aattttctcg tgcccaagac ttgggtggcc
     7501 tgattgcccc taactttgcc ttgggtgctg tcttactcat gcaatttgcg acgcaggctg
     7561 ccaaatattt cccaaatgtg gagattattg agctccatca tgacaagaaa aaggatgctc
     7621 cgagtggaac agccattaaa acagctgagt tgatggcaga ggttcgagag tcaattcagc
     7681 aaggtgcagc agatgaggaa gagctgattg ctggtgctcg tggtgctgac tttgatggta
     7741 tgcgcatcca ctcagttcgt ttgccaggct tggtagctca tcaggaagtc atctttggca
     7801 atcagggaga agggttgacc ctccgtcatg actcctatga tcgcatctcc ttcatgacag
     7861 gagtcaattt gggaattaaa gaagttgtca agcgtcatga gcttgtctat ggattagaac
     7921 acttattatg agattaacgc aaatgccttc tgaatttcag aaggctttac cagtattaga
     7981 aaaaattaaa gaagcaggct ttgaggctta ttttgttggg ggctctgttc gagatgccct
     8041 tctccatagc cctatccacg atgtggatat tgcgacgtct tcttatccag aagagaccaa
     8101 gcagattttt ccgcgaacag ccgatatcgg aatcgagcat ggaaccgtct tggtcttaga
     8161 tggggatgag gagtatgagg taacaacctt tcggacagag gatgtctatg tggactatcg
     8221 cagacccagt gcggtttcct ttgtgcgctc gctagaagaa gacctcaaac gccgtgattt
     8281 cacagtcaac gcctttgcct tggatgagac aggagaaatc gttgacttgt tccatggttt
     8341 agaagatttg gaaaagcaag tcttgcgagc agttggagtg gctagtgagc gtttcaacga
     8401 agatgcttta cggattatgc gtggtttccg ttttcaggct agtcttggtt ttgcacttga
     8461 gccagaaaca tttaaagcta tgaagacctt gacgccgctt ttggagaaaa tttctgtaga
     8521 gcgtaccttc gtcgagtttg ataaactctt gctggctcca ttttggagaa ggggcttggc
     8581 ttccatgatt gagagtcaag cttatgacta tctccctgat atggcatcta gccaggacaa
     8641 gctcaacaga ctgtttgatt tggagactga ttttactttt gaatcctctg aacaagcctg
     8701 ggcggcttta ctatgggctt tggagattga aaatgcgcag tcatttttga aatcttggaa
     8761 gacctcacgc cagtttgcca agcaagttca ggatttgctg attattttgg ctctgcgtga
     8821 aaatggagaa ttgagcaagc gagattgtta tcgctttgat atagatttgc ttttacaggc
     8881 tgaaaatctt cgtcaagctc aaggaaaaga agtcaaccta caagccatca cagaaaaata
     8941 ccaaagcttg actatccatg acaagaaaga gattcagatt aatggcgata ttttgatcaa
     9001 ggaatatggc tatcagccag gcccagactt gggagagatt ttaacagaga ttgagtttgc
     9061 cattgtcgat ggagaattgg agaataatcg tgaagccatc catgcttacc tgagggagaa
     9121 aaaatgagtg attttatcgt tgaaaaacta agtaaatccg ttggtgacaa gaccgttttt
     9181 agggatattt cctttattat ccatgactta gacagaattg gtttaatcgg tgtcaatggg
     9241 actggcaaga ccaccctttt ggacgtcctt tctggtgttt ctggatttga tggggatgtc
     9301 agtccttttt cagctaaaaa tgattaccag attggttact tgactcagga tcctgatttt
     9361 gatgatagaa agacagtttt ggatacggtt ctatctagtg aactcaagga aatccagctc
     9421 attcgtgagt atgaattgat tatgctcgac tatagtgagg acaagcaggc gcgtttggaa
     9481 cgtgtcatgg cagagatgga ctctctccaa gcttgggaaa tcgagagtca ggtcaagacc
     9541 gttcttagca aattgggcat tcaagactta tctactcctg ttggggaatt gtcaggtggt
     9601 ctgagaagac gggtacagtt ggcacaagtc ttacttggca accacgacct tttgcttttg
     9661 gatgagccga ccaaccatct ggatattgcg attattgagt ggctgaccct ctttttgaaa
     9721 aattctaaga agaccgtcct ttttatcact cacgatcgtt atttcttaga cgctttgtca
     9781 acacggattt tcgagttgga gcgagcaggc ttgacagaat atcagggcaa ttaccaggac
     9841 tatgttcgcc ttaaggcaga acaggacgag cgcgatgcag ctctacttca taaaaaagaa
     9901 caactctaca aacaagaact ggcctggatg cgcagacaac cgcaggcacg tgcgaccaag
     9961 caacaagctc gtatcaatcg tttccatgat ctgaaaaagg aagtttcagg cagtagtgct
    10021 gagacagact tgactatgaa ctttgaaacc agtcggattg ggaagaaagt catcgagttt
    10081 caggatgttt cctttgccta tgaaaacaag cccattttgc aagattttaa tctcttggta
    10141 caggtcaaag atcgtatcgg aatcgttggg gacaacggtg ttggaaaatc aaccttactc
    10201 aacttaattg caggaagtct tgagtcaact aaaggacaag ttgtgattgg ggaaactgtt
    10261 cgcatcgcct atttctctca gcaaattgag ggcttggatg aaagcaagag agttatcaat
    10321 tacctgcagg aagtggcaga ggaggtcaag accagtggtg gttctacgac ttcgattgca
    10381 gagttgctgg agcagttcct tttcccacgt tcgacgcatg gaaccttgat tgagaaattg
    10441 tcagggggtg agaaaaaacg tctttatctc ctcaaactgc ttttggaaaa accaaatgtt
    10501 cttcttttag acgagccaac caatgaccta gatattgcaa ctttgacagt cttggagaat
    10561 ttcttgcaag gttttgcagg tcccgtttta acagtcagtc acgaccgcta tttcttggat
    10621 aaggtagcga ccaagattct cgcttttgag gatggcaaga ttcgtccttt ctttggtcat
    10681 tacaccgact atcttgatga aaaagctttt gaaacagata tggccaatca agtgcaaaag
    10741 gccgaaaagg aaaaagtggt caaggttcga gaagacaaga aacgcatgac ctaccaagaa
    10801 aagcaggagt gggcaagtat tgaaggtgat attgaaacct tggaaaaacg tatcgctgct
    10861 attgaagagg aaatgcaggc taacggctct gactttggta agctggctac tctccaaaaa
    10921 gaattggatg agaaaaatga agcactcctt gaaaaatacg aacgctatga gtatctcagt
    10981 gaatttgata gttaagacta ttcgaaaatc aaagtgcaaa ctatgtcggc ttcacattgc
    11041 cgactcaagt acagcctgtg accggcttcc taatttgcac tttgattttt attgagtata
    11101 aaagaataga aaaatcccgt ctcatgaaag gatttctcta ttcttttttg gtttcttgat
    11161 gaaagatatt ttgccaggtt tcgtggcgac gccagatact ggtatggatg ataccatcta
    11221 actcatagca gatgagtttg gttttttgac tgatggaagt aatttgaatg tccttgatag
    11281 cagaatttaa ctcttttttg gtcttataag cctctttatc catctgctct ccatcttggc
    11341 gaatatagac aaaatcatca gtcaagagtt cttctagttg gtttccttgg tcaatcaatt
    11401 gttcacgcat aagcaatttt ttatagacat tgtctaaaat ttcatcctca gggataggtg
    11461 ctggttcgat atggacatcg gtatcaaaga cgccaaaacg ctcctccagc atagactcga
    11521 cctgatccgc gatttcatgg ctttcaaaaa cagacaagtc aggattcatc tctagtgtaa
    11581 tatccaggta gatgttgcta ccgtaggtgc gacctctttg cgatttgacc ttgctgattt
    11641 tgggaatttc catgatagcc ttttggtagt cctcgagcag gcggtcgtca aagccatctg
    11701 aaagactaaa ggaagactcg atgaagatat cataggcagt cttcaagata aagaaagtga
    11761 tgatgatagc aaccagttta tccacaatcg gataattgaa actactagct aggatggcaa
    11821 tggcggttcc aagtgaggta acagcgtcag aaagattgtc cttagcagct gccttcagcg
    11881 ccttggagtt ggatttctta ctgaggcgag tattgtagag atagaccaca aacataatcg
    11941 ctgcagaaat gattcctaga gttgcaccaa gaggatcaat gaccgtttct tcccgactga
    12001 gaatcttttg aatggtatct cttagaacat cgaaaccgac atagaacatg atgatagaag
    12061 tgatcaagct tgccaaatct tcaatcttcc aatgaccaaa acggtggtca cggtctgcag
    12121 gctggcgcgc catccgaatc ccgattaaga gggccacatt tccaatgatg tccgatacgt
    12181 tattaaaacc atcggccacc aaactggatg aatgaaggag atgaccagct gctaatttgg
    12241 ctgcagacaa gatcaaatag gtcgaaatac tgataatggc tccacgctca gctaacttga
    12301 gatttgagat agattgcttc attcaacttc ctttctagtc acatagcatt ctaccattat
    12361 actggttttc aaggaaaaat tcaaataagg cagtttttac tctttgaaaa ctccccaaaa
    12421 tttggtataa tggtactact caagggagta gctggcagaa acctgtgata gtgtcgtcat
    12481 tccgaatttt atgctgaaaa gtatgctttc cggccctatc ttaaacagcg agacttgtta
    12541 tgattaacag gtctcttttt gtttgtcgtg aaaagatatg acagaaagag agtctgtttt
    12601 gcacacaatg tcaaggagga gacacatgtc aaaagaacaa aaacgccaag cgttttatac
    12661 tcagagccct gaagaggtct tgcaggctgt ggatgcgacc gagcaaggtt tgtcatcaag
    12721 tgaggcggaa aagcgccttg ccgaatttgg gcacaatgaa ctcgaagaag gcgagaaacg
    12781 atcaatcttg gtcaaattca tcgagcaatt taaggatttg atgattatca tcctagttgc
    12841 ggcagcaatc ttgtcagtcg tgacttctgg tggggaagat atcgcagatg ccattatcat
    12901 cctagctgtg gttatcatca acgctgcctt tggtgtttac caagaaggaa aagctgaaga
    12961 agctattgaa gccctcaaat ccatgtctag tccagttgcc cgcgttcttc gtgatggaca
    13021 catggcagag attgactcta aagaattggt accaggcgat atcgttgccc ttgaagcagg
    13081 tgacgtggta ccagcggacc tacgtttgct agaagccaac tctcttaaaa ttgaagaagc
    13141 agccttgacg ggtgaatctg taccagtcga aaaagacttg tcagtcgagc ttgcgacaga
    13201 tgctggtatt ggtgaccgtg tcaacatggc cttccaaaac tcaaacgtaa cctatggtcg
    13261 tgggatgggt gttgttgtca atacaggtat gtacactgaa gttggtcata ttgctggtat
    13321 gcttcaagat gcggatgaga ctgatacacc actcaaacaa aacttgaaca acctttctaa
    13381 ggtcttgacc tatgctatct tggtcattgc ccttgttact tttgtagtgg gtgtcttcat
    13441 tcaagggaaa aatccacttg gtgagttgtt gacttctgtt gcccttgctg ttgcagccat
    13501 tccagaagga cttcctgcta tcgttaccat cgttctttct cttggtactc aagttttggc
    13561 caaacgacat tccatcgttc gtaagttgcc agcagttgaa acacttggtt caactgaaat
    13621 catcgcttct gataagactg gtacgctgac tatgaacaag atgacagtcg aaaaagtctt
    13681 ctacgatgcg gttctacatg actcagctga tgatattgaa ctaggtcttg aaatgccact
    13741 acttcgttca gttgtcttgg ccaatgatac gaaaatcgat gtggaaggta acttgattgg
    13801 tgacccaacc gaaacagcct ttatccaata tgccttggac aagggctatg atgtcaaagg
    13861 tttcttagag aaatatcctc gtgtagctga attgccattt gactctgacc gtaagctcat
    13921 gtcaacagtt cacccattgc cagatggtcg tttccttgta gcagtcaagg gtgcgccaga
    13981 ccaactctta aaacgttgtc ttcttcgtga taaggctggg gatattgctc cgattgatga
    14041 gaaggttaca aatctcattc atacaaacaa ttctgaaatg gctcatcaag ccttgcgtgt
    14101 ccttgcaggt gcttataaga ttatcgatag tattccagaa aatctcactt ctgaagagct
    14161 tgaaaatgat ttaattttta ctggtttgat tgggatgatt gatcctgaac gtcctgaagc
    14221 tgctgaggct gttcgtgtgg ctaaggaagc tggaattcgt ccaattatga ttacaggtga
    14281 ccaccaagac accgcagaag ctattgccaa acgtttggga atcattgacg caaacgatac
    14341 agaagaccac gttttaactg gtgctgagct caacgaatta tctgatgaag actttgaaaa
    14401 agttgttggt caatactctg tttatgcccg tgtgtctcca gagcacaagg ttcgtatcgt
    14461 caaggcttgg caaaaacaag gtaaggtcgt tgccatgaca ggtgacggtg tcaatgatgc
    14521 cccagctctg aaaacagcag acatcggtat cggtatggga atcactggta cagaggtttc
    14581 taagggggct tctgatatga ttcttgcaga tgataacttt gcgactatta tcgtcgcagt
    14641 ggaagaagga cgtaaggtct tctcaaatat tcaaaagact attcagtacc tactttctgc
    14701 caatactgct gaagtattaa ccatcttcct atcaaccttg tttggttggg acgtcttgca
    14761 gccagttcat cttttgtgga ttaacttggt aacggatacc ttcccagcaa ttgcactagg
    14821 tgttgaacct gcggaacctg gtgtcatgaa tcataaacca cgtggacgca aggcaagctt
    14881 cttctcaggt ggtgttttga gttctatcat ttatcaaggt gtactccaag cagctcttgt
    14941 tatgagtgtt tatggccttg cgattgctta cccagttcat gtgggtgaca atcatgctat
    15001 tcatgcagat gccctaacga tggcctttgc aacccttggt ttgattcagc tcttccatgc
    15061 ctacaatgtc aagtctgtct accaatccat cttgacagtt ggcccattca agtctaagac
    15121 ctttaactgg tccatcttgg tatcctttat ccttctcatg gcaacaatcg ttgtagaacc
    15181 gcttgaagga atcttccacg taaccaaact agacttgtca caatggggaa ttgttatggc
    15241 tggaagcttc tcaatgatta tcatcgtcga aatcgttaag tttattcaac gcaaactcgg
    15301 ttttgacaag aatgcgattt aagggaggtt tcggatgtca gcatatcaat taccgaccgt
    15361 atggcaggat gaagctagta atcaaggagc ttttacgggg ctaaacagac caacagtagg
    15421 tgcccgtttc gaacaaaact tgccaaaagg agaacaagct tttcagcttt attcactggg
    15481 aacaccaaat ggtgtgaagg ttactatctt attggaagaa ttactagaag ctggttttaa
    15541 ggaagcggct tacgacttgt ataagattgc tatcatggat ggggatcaat tcggatcaga
    15601 ctttgtgaag ctcaatccaa attccaagat tccagcctta ttggaccagt caggtactga
    15661 agatgtaaga gtctttgagt ctgctcatat tcttctttac cttgctgaga aatttggagc
    15721 ctttttacca agtaatcctg tggaaaaggt agaagttttg aattggctat tctggcaagc
    15781 aggtgcagca ccttttctag gtgggggatt tggacatttc ttcaattatg ctcctgaaaa
    15841 attggaatat cctattaacc gttttacaat ggaagtgaaa cgccagttgg atttattgga
    15901 taaggaattg gctcagaaac cttatattgc aggcaatgac tatacgattg cagatattgc
    15961 tatctggtct tggtatggac agttagttca aggaaatctt taccaaggtt ctgcaaaatt
    16021 cttggatgcc tcaagttatc aaaatctagt aaaatgggca gaaaaaattg ccaatcgtcc
    16081 agctgttaag cgtggcttgg aagtaactta tacagaaatt aaatagcaaa aaagtcatct
    16141 tcggatggct ttttgctaca gttgagggaa agggtttgca gttatcggct tttgtgctat
    16201 aattgctata atatagtaaa aagcaagagg agtgtgagga agtggaaaag aaaattgtga
    16261 aggatatctt atttttatct caagtgtctc agccggcaag tcaggaggac ctttatcttg
    16321 ccagagattt gcaggataca ctcttagcaa atcatgatac ctgtgttggt ctagctgcca
    16381 atatgattgg ggtgcagaag cgcgtgatta tctttaatct tggcttggtt cccgtggtca
    16441 tgtttaaccc agtgcttctg tcctttgaag gatcctatga ggcagaagaa ggctgtttgt
    16501 ccttggtagg cgtgagatca actaagcgtt atgaaaccat aagggttgcc tatcgtgaca
    16561 gcaagtggca ggaacagacc attaccttga caggcttccc agctcagatt tgccagcatg
    16621 agctggatca cttggaagga cgaatcattt aggaggaaag caaatgaaac gaatagtctt
    16681 tgaacttatt tttatcgcaa cgacctggta tatcttttta ccgcccctta acctgaccag
    16741 ctgggaattt ctcttcttcc tctgtgggca tttgttagtt gtggcaatct tatttggctt
    16801 tggcaagggg ataaaccttg tcaaaacggt tcatgtgcgc cacggtaagg cggaagctgc
    16861 cttaaatctt gagggtttca aaatcaatcg gttagggaaa attctgttag cttcgattgg
    16921 aggaattctt ctcttggcag ctttggtttc cttggtaact tccagcatgt ttcaggctaa
    16981 aaattatgcc aatgtagtca cggttacgga aaaagacttt actgaatttc ctaggagtga
    17041 caccagtaag gttcctatcc tagatagaag tactgctgaa aaaattggag accgctactt
    17101 gggttcccta accgataagg tgtcgcaata cgtagcggca gatacctata cccaattgac
    17161 aattgatggg aaaccttatc gggtcacacc actagaatat gcagacccta tcaaatggtt
    17221 taacaatcaa gccaagggaa tcggtgagta tatcaaggtg gacatggtaa ctggaaatgc
    17281 ggatttggtg gacttgaaga caccaatcaa gtattcagac tcggagtatt ttaaccgtga
    17341 tgtcaaacgt cacctgcgct tgaagtaccc gaccaaaatc tttaaaactc catcttttga
    17401 ggtggacgat gagggcaatc ctttctatgt agcaacggtt taccaaaagc aatttggact
    17461 tgctgttcct cgtcctgctt cagtcattat cttggatgct acaaatggag aaaccaagga
    17521 atacagctta tcagatgttc cagaatgggt ggacaggatc tatccagcag aggaaaccat
    17581 tgagcaaatc aactacaacg gcaagtacaa ggacggtttc ttgaatgcca tgatttccaa
    17641 gaaaaacgtg acccagacta ccaagggcta taattacttg tctatcggta atgacatcta
    17701 tctctacaca ggtgtgacgt cggctaatgc ggatgagagt aatcttggtt tcatccttga
    17761 aaatatgcga acaggagaaa tcactaagta tagcttggct tctgcgacag aagaatcagc
    17821 ccgtgaatca gcagaaggtg ctgttcagga gaaatcctac aaagcaacct tcccaatcct
    17881 catcaacctc aatgacaagc ctctctacat catgggcttg aaggacaatg ctggcttggt
    17941 caaagagtac gccctggtag acgcagtcga gtaccaaaat gttatcgttg ctactacagt
    18001 ggaagagatg ctcagcaagt atgccaataa aaacgacctt gaaattgaca atgcaacgac
    18061 agaaagcatc aatggagtag tagcagacct caaatcagct gttatcaagg gagacactgt
    18121 ctacttcttt aaagttgatg gcaagatata caaggtcaag gcttcagtat ccgatgacct
    18181 tccttacctt gaaaatggta aaaccttcga aggtcaagta ggaaaagaca attatctcaa
    18241 gacctttaaa gtacaataat actcttcgaa aatctctagc tctatctgca acctcaaaac
    18301 agtgttttga gcagcctgcg gctagtttcc tagtttgctc ttt
//
LOCUS       DAVLIK010000038        16197 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLIK010000038 DAVLIK010000000
VERSION     DAVLIK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16197
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.038"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            66..230
                     /locus_tag="VXE87_001504"
     CDS             66..230
                     /locus_tag="VXE87_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0843031.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            309..1037
                     /gene="yaaA"
                     /locus_tag="VXE87_001505"
     CDS             309..1037
                     /gene="yaaA"
                     /locus_tag="VXE87_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0843032.1"
                     /translation="MKILIPTAKEMNTDLPSIEATPLKPESQAVLDALALYSASQLES
                     FYKVSAEKATEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(1315..1863)
                     /locus_tag="VXE87_001506"
     CDS             complement(1315..1863)
                     /locus_tag="VXE87_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0843033.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            2184..2672
                     /locus_tag="VXE87_001507"
     CDS             2184..2672
                     /locus_tag="VXE87_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0843034.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            2669..3856
                     /locus_tag="VXE87_001508"
     CDS             2669..3856
                     /locus_tag="VXE87_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0843035.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAAVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            3849..4214
                     /locus_tag="VXE87_001509"
     CDS             3849..4214
                     /locus_tag="VXE87_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0843036.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            4230..5576
                     /gene="asnS"
                     /locus_tag="VXE87_001510"
     CDS             4230..5576
                     /gene="asnS"
                     /locus_tag="VXE87_001510"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0843037.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            5729..6019
                     /locus_tag="VXE87_001511"
     CDS             5729..6019
                     /locus_tag="VXE87_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0843038.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            6031..6501
                     /gene="ssbA"
                     /locus_tag="VXE87_001512"
     CDS             6031..6501
                     /gene="ssbA"
                     /locus_tag="VXE87_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0843039.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LERRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            6533..6772
                     /locus_tag="VXE87_001513"
     CDS             6533..6772
                     /locus_tag="VXE87_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0843040.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            7067..8467
                     /locus_tag="VXE87_001514"
     CDS             7067..8467
                     /locus_tag="VXE87_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0843041.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            8469..8828
                     /locus_tag="VXE87_001515"
     CDS             8469..8828
                     /locus_tag="VXE87_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0843042.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            8882..9631
                     /locus_tag="VXE87_001516"
     CDS             8882..9631
                     /locus_tag="VXE87_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0843043.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            9621..9920
                     /locus_tag="VXE87_001517"
     CDS             9621..9920
                     /locus_tag="VXE87_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0843044.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            9991..10926
                     /locus_tag="VXE87_001518"
     CDS             9991..10926
                     /locus_tag="VXE87_001518"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0843045.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            11012..11524
                     /locus_tag="VXE87_001519"
     CDS             11012..11524
                     /locus_tag="VXE87_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0843046.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLRDSDF"
     gene            11561..12079
                     /locus_tag="VXE87_001520"
     CDS             11561..12079
                     /locus_tag="VXE87_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV0843047.1"
                     /translation="MIRYLDQYEDVILCENKRHYLNFPTLESLDSLELDQEIFVREAS
                     PVYQALLEQSFETELRNQINAAILVEKTDFARIKMTLSNYFYKVKQQYPLTEKQQELY
                     DILGDVNPEYALKYMTAFLLKFLKKDQLMQKCRDIFVDSLVVLGYIVQNEDRKYELAI
                     DFDKERLTFYLA"
     gene            12180..12377
                     /locus_tag="VXE87_001521"
     CDS             12180..12377
                     /locus_tag="VXE87_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0843048.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(12420..13865)
                     /locus_tag="VXE87_001522"
     CDS             complement(12420..13865)
                     /locus_tag="VXE87_001522"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0843049.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMVIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            13971..15593
                     /locus_tag="VXE87_001523"
     CDS             13971..15593
                     /locus_tag="VXE87_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0843050.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            15796..>16197
                     /locus_tag="VXE87_001524"
     CDS             15796..>16197
                     /locus_tag="VXE87_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein"
                     /protein_id="HEV0843051.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEAL"
BASE COUNT         4752 a         3056 c         3648 g         4741 t
ORIGIN      
        1 aaaaaggttt atttaataaa tatatgttat aataaggtaa attaagccta atggaggaca
       61 aagaaatggg tttttatttg atggttgctt caatgctact cggactgctc gctttgaaga
      121 taggtttttc tcagttcaag gagaaaaaag ataaattctt atctatctta acaagtttag
      181 ctggcatagc ccttgttctc gcggctgtct ggttaggatg gcccaaataa atagaaaaac
      241 ctcagtcaaa ccgaggtttt tcaaatgaat ttcttggttg tggctaaaaa atatgctaca
      301 ctatcaatat gaaaatttta atcccaacag caaaagaaat gaacacagac ttgccaagta
      361 tcgaggcaac tcctttaaaa ccagaaagtc aggccgtgct tgatgccttg gctctctatt
      421 ctgccagtca attggagagt ttctacaagg tatcagctga gaaagcgacg gaagaatttc
      481 aaaatatcca agctttgaaa aggcaaactg ctcaacacta tccagccttg aaactttttg
      541 atgggcttat gtaccgcaac attaagagag ataagctgac cgaggcggaa caagattatc
      601 ttgaaaatca tgtcttcatt acctcggctt tgtacggtgt tgttccagcc ttgtcaccca
      661 tggctcctca ccgtttggat tttttgatga aattaaaagt cgctggtaag actttgaaga
      721 gccattggaa ggcagtctat gatgaagctc tgaagaagga agaagtgatt ttctctctct
      781 tgtcatcaga gtttgagact gtattttcta aggaaatcag agcaaagatg gtgaccttca
      841 aattcatgga ggatagaggc ggtcagctga agattcactc aactatctcc aagaaagcgc
      901 gcggggcctt tctaacagct ttaatagaaa atcaagtaca aactgtgggg gaagcacgtc
      961 gcttgaactt tgctggattt gtttaccgag aagatttgtc acaaccacag ggattggttt
     1021 ttgtaaagga agtatagaaa tcagatattt tgtatttggc aatatgtatc atcagctgtt
     1081 ttagtttata aatgagaaaa aaagcgaaca agctagtctt ctgagtgtca gaaaagtagt
     1141 cttgttcgct tttattatgt tatactcttc gaaaatctct tcaagccacg tcagcgtcgc
     1201 cttaccgtat atatgtcact gacttcgtca gttctatcta caacctcaaa gcagtgtttt
     1261 gagcagcttg cggctagctt cctagtttgc tttttgattt ttattgagtg ttagttactt
     1321 gatagcttcg accaagtctt gagcttgttt ttcaagtgag tttaggactg tttcttcaag
     1381 aaccaatttt ccgtctgccc aggcagagtc attaacacgt gcagcagtga aatcaccaac
     1441 gccttgtgta cggataaatg gcaagaggtc tttgtagata gcgaaaagtt gatcgtgccc
     1501 tgcattggct acagatgata ctgtgacaaa cttgtcttga agggcagaaa cgccacgtgt
     1561 atcagacaag tcaagggcac gagatagcca gtcaagcaag tttttcactg taccagggat
     1621 agagaagttg tagactggag agaaaatcca gatagcatcc gcaacgagaa ctgcttcacg
     1681 agcagcagct acagctggat gtgttggaac ttccaaatct tggctgaaga gaggaagggc
     1741 tgaataatca aggtagctaa cttccgcttt accagcaagt gctttctcag cttcgagcgc
     1801 catttggtgg ttgaaagaac cttgacgtag tgatccgacg ataaataata cttttttaga
     1861 catgatgtgt ctcctttttc ttaaaatttc gagaactctc tcgttgttat aaaatatatt
     1921 acaacaaaac aaaagaactt gcaagaaatt tgctcagagt ttatttgaaa attgtaaaat
     1981 ttcggaaact ctagtcattt gtgactgaaa aagtaagaac tgtttcactt tcaaaatcgg
     2041 ttttgtttga agggagaaat agaattggtt gctcaaagca cagctttgag gttgcagata
     2101 aagctgacgt ggtttgaaga gattttcgaa gagtattctt atattcactt gtaataaagc
     2161 ttaatagatg gtaaaataga cgagtgaaaa aaagacaaaa caaagcaaaa aataatctac
     2221 tgtggcagta tggtctaggg atgacgattt tgtttgtggt tatcagtgct tcctttctgt
     2281 atatggtttc tcttagcatg aaaccctatc aaacagctaa aagtgaagga gaaaaattag
     2341 ctcagcagta tgcaggatta gagcaggccg atcaggttga tttatacaat ggcttggaat
     2401 cttattacag cgttcttggt cgtaataaac agcaagaagc acttgctgtt ctgattggaa
     2461 aagatgatca taagatttac gtttatcagc taaatcaggg tgtttcacaa gaaaaagcag
     2521 aaacggtttc taaggaaaag ggagctggcg aaattgacaa gattatcttt ggtcgttatc
     2581 aagataagcc aatctgggaa gtcaagtcag gatctgattt ttatctagta gattttgaaa
     2641 caggagcatt ggtcaacaag gagggcctat gaaattatcc aaccgtgttt tagaaatgga
     2701 agaaagtgtg actttggctg ctggagcccg tgccaaagca ctgaaggctg agggcagaga
     2761 tattttgtct ctaaccttgg gtgagccaga tttcactact cccaaaaata tccaagatgc
     2821 cgccattgca tcgattcgag atgggcgtgc ttctttttat acagtaacct caggtctgcc
     2881 agagcttaag gcggcggtca atagctactt tgagcgcttt tacggctatt ctgtagcgtc
     2941 aaatcaagtg acagtcgctg cgggagccaa atattctctc tataccttct ttatggctgc
     3001 ggtcaatcca ggtgatgaag tcatcatccc aaccccatac tgggttagct atggagatca
     3061 ggtcaagatg gcagaaggcg ttcccgtctt tgtttctact aaggaagaca atcactttaa
     3121 ggtgaccgta gatcagttag aagcagctcg cactgacaag accaaggttt tggtgctgaa
     3181 ttcgccatct aatcccacag gtatgattta cacccgtgag gaactcttgg caattggaaa
     3241 ctgggctgta gaaaatgata ttctcatcct agcagatgat atctatggcc gcttggttta
     3301 taatggtcat gagttcacac cgatttctag cctatcggaa gcgattcgca agcaaacagt
     3361 ggtcatcaat ggtgtttcta aaacctatgc catgactggt tggcggattg gttatgccgt
     3421 tggagaagca gacattatcg ctgccatgtc caagattgca ggtcaaacaa cttcgaatcc
     3481 gtcagcagta gcccaatatg cagcagttga ggctctatca ggtgagcaag atactgtaga
     3541 aagcatgcgt caggcctttg aggaacgtct taataccatc tatcccctcc ttgcagaggt
     3601 gccaggattt gaagtggtca aaccgcaagg ggccttctat ctcttcccaa atgtcaaaaa
     3661 ggccatggag atgaaaggct acacggatgt gacagacttt acaactgcta tcttagaaga
     3721 agccgaagtg gccttggtaa caggagctgg atttggagca ccagaaaatg tccgcctcag
     3781 ctatgcgaca gacctagaca cgcttaaaga agcagtcgaa cgcttgaaag catttatggg
     3841 tagtgagaat gattgatcat tttgagatta aggtaaagga tttacaaatt tcagaaggat
     3901 tttataggag ttttctcgct cctttggact ataaattggc ttttaagact agttctctaa
     3961 ttagttttct atccccgaac agccctcatc ctggtggtga tttttggctg actcagggaa
     4021 cacaagatcc tgttcatttt gcttttttag cagaaaataa ggaagaagtt caggcttgtt
     4081 atgaggctgg cttagaggca ggtgggcgag acaatggggc tcctggttat cgaagtgagc
     4141 atccgattta ctatgctgct tttatgattg acctggatgg gaacaatata gaggtggttt
     4201 gccataaaga ataaaaaaga aaaggaaaaa taatgacaaa acgtgtaacg attattgacg
     4261 taaaagacta tgttggtcag gaagtgacga ttggcgcttg ggttgccaac aaatcaggaa
     4321 aaggaaaaat cgctttctta caattgcgtg atggaacagc cttctttcaa ggtgtggctt
     4381 ttaaaccaaa ctttgtcgaa aaatttggtg aagaagtggg acttgagaag tttgatgtta
     4441 tcaaacgctt gagccaagaa acgtctgttt atgtgacagg tattgtcaaa gaggacgaac
     4501 gttctaaatt tggctatgag ttggacatca cagacatcga agtgatcggt gaatctcaag
     4561 actacccaat cacaccaaaa gaacacggaa cagacttttt gatggataac cgtcacttgt
     4621 ggctacgctc tcgtaagcaa gtagctgtgt tgcaaatccg taacgctatt atctatgcaa
     4681 cttatgagtt ctttgacaag aacggtttta tgaagtttga cagcccaatt ctttcaggaa
     4741 atgcggcaga agattctaca gaactctttg aaactgacta cttcggaacg ccagcctact
     4801 tgagccaatc aggtcagctt tacctagaag caggggctat ggctcttggt cgtgtctttg
     4861 actttggtcc agttttccgt gctgaaaaat caaaaacacg ccgtcacttg actgaattct
     4921 ggatgatgga tgctgagtac tcatacttga cacatgatga gtcgcttgac ttgcaagaag
     4981 cttatgtgaa agctcttcta caaggtgttc ttgaccgcgc gcctcaagcc ttggaaacct
     5041 tggaacgtga tacagaactc ttgaaacgct acattgcaga gccattcaaa cgtatcactt
     5101 acgatcaagc cattgacctc ttgcaagagc atgaaaatga tgaagatgct gactacgagc
     5161 atcttgagca tggtgatgac tttgggtcac cacacgaaac ttggatttca aaccactttg
     5221 gtgtgccaac atttgtcatg aactatccag cagccatcaa ggccttctac atgaaaccag
     5281 ttcctggaaa tccagagcgc gtgctttgtg cagacttgct tgctccagaa ggctatggag
     5341 aaattatcgg tgggtctatg cgtgaggaag attacgatgc ccttgtcgct aagatggatg
     5401 aacttggcat ggatcgtaca gaatatgaat tctaccttga ccttcgtaaa tacggtacag
     5461 ttccacacgg aggatttggt atcggtatcg aacgtatggt aaccttcgca gcaggaacaa
     5521 aacatatccg tgaagctatt ccattcccac gtatgttgca ccgtatcaaa ccataagaac
     5581 aggaaaacgc ccatgtggcg ttttttcgaa ttctagtgtt tttacttgcg taaaaaaaat
     5641 ttttctagta taatagttta ttgtgagcga acctcactta ccccttgcaa agtcttgggg
     5701 tcattagacc aaaaggagga acatatcaat ggctaaatac gaaattcttt atatcattcg
     5761 tccaaacatt gaagaagaag ctaaaaacgc tttggtagca cgttttgact ctattttgac
     5821 tgacaacggt gcaactgttg ttgaatcaaa aacttgggaa aaacgtcgtc ttgcatacga
     5881 aatccaagat ttccgtgaag gactttacca catcgttaac gttgaagcaa atgacgatgc
     5941 agctcttaaa gagtttgacc gtctttcaaa aatcaacgct gacattcttc gtcacatgat
     6001 cgtcaaaatt gacgcgtaag aaggtaaact atgattaaca atgttgtact tgtagggcgt
     6061 atgacacgtg acgctgagtt gcgttatacc ccatcaaatg tagcagttgc gacttttact
     6121 cttgcagtaa accgtacatt taagagtcaa aatggtgaac gtgaggctga ttttatcaat
     6181 gtcgttatgt ggcgccaaca ggctgaaaat cttgctaact gggctaaaaa aggctcactt
     6241 atcggggtga caggtcgtat ccagactcgt agttacgata accagcaagg acaacgtgtc
     6301 tacgtgacag aggtcgtggc tgagaatttc caaatgttgg aaagacgtag tgtgcgtgag
     6361 ggtcacacag gtggagctta ctctgcacca actgcaaact attcagcacc tacaaattca
     6421 gtaccagact tttcacgtaa tgaaaatcca tttggagcaa caaacccatt ggatatttca
     6481 gatgatgatt taccattcta atggacaact aaacttataa aggagaaaaa acatggctca
     6541 acaacgtcgt ggcggattca aacgccgtaa aaaagttgat tacatcgcag caaacaaaat
     6601 tgaatatgtt gattacaaag atactgagct tcttagccgt ttcgtttcag aacgtgggaa
     6661 aatccttcct cgtcgtgtaa caggaacttc agctaaaaac caacgtaaag taacaacagc
     6721 tatcaaacgc gctcgcgtaa tggctttgat gcctttcgta aacgaagatt aaagaaaaga
     6781 cccagttggg tctctttttc atgagcttga aaacaagaaa gcgaattaag accccaacgg
     6841 gtcttttttc acaagctttg aaatgagaga gcgagttagg ctcagtggct ccctttttac
     6901 gagtttgaaa acaagagaac acattaaaag cacgatggag ctttttcata aatatgtctc
     6961 ttttctcatc caagaaatta aaataaaaat gataaacttt ttgaaaatag gggatttgcc
     7021 tactttatga tataatggaa agagttagat tgaaagaggt agtgagatgg acgcgaaatt
     7081 aagatacaag gcaaagaaga tcaagattgt cttttttgat attgatgata cattgcggaa
     7141 ttcaaagaca gggtttattc caactacaat tcccactgtt tttaaacagt tgcgtgaaaa
     7201 aggaatttta acaggaatcg cctctggacg tggcattttt ggtgttgttc cagagattcg
     7261 tgatctcaag cctgactttt ttgtaacttt gaatggggct tatatcgaag ataaaaaagg
     7321 tcaggtcatt tatcagcatc agattgaaaa gtcagatgtt gaggagtata tctcttgggc
     7381 taagcaagaa ggaattgagt atggcttggt tgggagtcat gatgccaagt tgtcgactcg
     7441 caccgatatg atgagtgaag ctatcaatcc aatttatccc gacttagatg tagatcccga
     7501 tttccatgaa aaagaagata tctatcagat gtggactttt gaagataagg gagatgactt
     7561 gcacttgcct gacagtctct cagacaaact tcgcatggtt cgttggcatc aacattcgtc
     7621 tgatattgtg ccgatttcag gctccaaagc gacgggggtg gaaaaggttg tggaacacct
     7681 tggcttgaaa ccagagaagg tcatggtttt tggagatggt ctcaatgact tggaactctt
     7741 tgattatgct ggaatcagcg ttgccatggg aatttctcat gataaaatca aagaaaaagc
     7801 agattatatt acaaaaacat tagaagaaga tggcattttt gatgccttag aagtatttgg
     7861 tatggtagaa aaagaattgc attttccaca agtagacatt gaaacagtag aaggtcctct
     7921 tgcgactatt aagaccaatc acggagactt acgtatcaag cttttccctg aacatgctcc
     7981 taaaacagtg gctaactttg tatctctttc aaaagatggc tactatgatg gtgtcatttt
     8041 ccaccgtatt atcaaggact ttatgatcca aggtggagac ccaactggaa ctggtatggg
     8101 tggcgagtca atctacggcg aatcttttga ggatgaattc tcagaagagc tttacaatat
     8161 ccgtggtgct ctttccatgg caaatgctgg tccaaatacc aacggcagcc agttctttat
     8221 cgtgcaaaac caacacctac cttattctaa gaaagaaatt actcgtggtg gttggccaga
     8281 accgattgca gaaatctatg ccaatcaagg tgggacacct cacctagacc gccgtcacac
     8341 ggtttttggt cagttagctg atgaagcatc ttacgctgtc ttggatgtca ttgctgctgt
     8401 tgagacagga gctatggaca agccagttga agatgttgta attgaaacta ttgaaatcga
     8461 ggactaagat gaaaatcggt gataagctaa aggggcgtat tacagggatt cagccctacg
     8521 gtgcctttgt tgagttagag acgggtgata cggggctgat tcacatttca gagattcgga
     8581 caggatttat tgaaaatatt catgaaacct tgaaagtcga tgaagaggtt caagttcagg
     8641 tagtggattt agatgaattt acagggaaag ccagtctttc tatccgcact ttggaggaag
     8701 aaaagtacca gtttcctaga cggagacgct tttcaagcga ccgctttaac tacggttttg
     8761 ctccctttcg acgaatgcta ccaatctgga ctggagaagc cctgcaccat ttaaaaaaga
     8821 agaagtagtt tagagtttta tattttttgt aatgttaata taaatttgct ataataggac
     8881 catggaagaa gaacaattat taaaatcagg agagcgcatt aaccagctct tttcgacaga
     8941 tatcaaaatc attcaaaata gagaggtttt tagctattcg gtggatagtg ttctcttatc
     9001 acgatttcca cgttttccta agaaggggtt gattgtggat ttctgtgctg ggaatggagc
     9061 agtggggctt tttgctagca ctcgtactca agcacagata ttgtctgttg agattcagga
     9121 gcgtttggcg gatatggctg aacgctctgt ccgtttgaat ggattagagg agcaaatgca
     9181 ggtcatctgc gatgatttga aaaatatgcc tgctcacatt caggggagta aggtggatat
     9241 gattttgtgt aatccaccct atttcaaggt ggatccttat tctaatctga acgagagtga
     9301 acattatctc ttggctcgac acgaaatcac gactaatttg gaagaaatct gtcatagtgc
     9361 ccagagtatt ctcaagtcta atgggcgttt ggccatggtt catcgtcctg atcgacttct
     9421 ggatattttg gatacgttaa aacgacataa tctagcccct aagcgcctgc agtttgttta
     9481 tccaaaaaga gaaaaggaag ccaatatgct tttgattgag gcgatcaagg atggctcaac
     9541 aagtggcttt aaggtcttac ctcctttgat tgtccacaat gatgatggct cttatacgcc
     9601 cgaaatcgaa gagatttatt atggatcata aggcttatat gtacgttctg gagtgtcgtg
     9661 atggatccta ctatataggc tatacgactg atatgagaag acgcctcgct atccacaata
     9721 gtgggaaggg agccaaatat acacgagcac gcttgccagt caaacttatc tatgctcaag
     9781 gttttgccag taaggaagaa gccatgtcgg ctgaagctct tctcaagcgt aagaagaggc
     9841 cacagaagga agaattttta tctgaaaatc aagatagaaa tttactcagt tattttgaag
     9901 aatcgtgggg agtcctttga ctcctcttac ctttgtcaaa aagcgaaaaa aatgctacaa
     9961 taaagaaaat aaacaaaatg aggtattatc atgtccaaga ttctagtatt tggtcaccaa
    10021 aatccagact cagatgccat cggatcatct gtagcttttg cctaccttgc aaaagaagct
    10081 tacggtttgg atacggaagc tgttgccctt ggaactccaa atgaagaaac agcctttgtc
    10141 ttgaactatt ttggtgtgga agcaccacgt gttatcactt ctgccaaagc agagggggca
    10201 gagcaagtta tcttgactga ccacaatgaa ttccaacaat ctgtatcaga tatcgctgaa
    10261 gtagaagttt acggtgttgt agaccaccac cgtgtggcta actttgaaac tgcaagccca
    10321 ctttacatgc gtttggagcc agttggatca gcgtcttcaa tcgtttaccg tatgttcaaa
    10381 gaacatggtg tagctgtgcc taaagagatt gcaggtttga tgctttcagg tttgatttca
    10441 gatacccttc ttttgaaatc accaacaaca cacccaacag ataaaatcat tgctcctgaa
    10501 ttggctgaat tggctggtgt gaacttggaa gaatatggtt tggcaatgtt gaaagctggt
    10561 accaacttgg ctagcaaatc tgctgaagaa ttgattgaca tcgatgctaa gacttttgaa
    10621 ctcaacggaa ataatgtccg tgttgcccaa gtgaacacag ttgacatcgc tgaagttttg
    10681 gaacgccaag cagaaattga agctgcaatg caagctgcca acgaatcaaa cggctactct
    10741 gactttgtct tgatgattac agatatcgtc aactcaaact cagaaatctt ggctcttggt
    10801 gccaatatgg acaaggtcga agcggctttc aacttcaaac ttgaaaacaa tcatgccttc
    10861 cttgctggtg ccgtttcacg taagaaacaa gtggtacctc aattgactga aagctttaat
    10921 gcgtaagatt ttgggtgtca gctcaaaatc ggaaagtcta gtttgcctta tatcgaaagg
    10981 agtttcggct ccttttttct aggagtgaag tatgttagaa aatggcgatt tgatttttgt
    11041 gagagatggg tcagacatgg gacaggccat ccagacttcc acaggtaact atagccatgt
    11101 tgccatttat ttggatggga tgatttatca tgctagtgga caggctggtg ttgtctgtca
    11161 agaaccggca gacttctttg agtccaatca tttatacgac ctctatgttt acccagaaat
    11221 ggatatccag tcggtgaagg aaagagcttg caaacatctt ggagcaccct acaatgcttc
    11281 tttctatcca gatgcagctg gtttctactg ctcccagtat atagcagaaa tcctacctat
    11341 ttttgaaact attcctatga aatttggaga tggggaacag gagattagtg atttttggag
    11401 ggagtattac atagaactag gtctgcctgt tcctctgaac caagctggga ccaatcctag
    11461 tcagttggca gcatcgcctc tgttacaatg taaagaaagg aatcttcgtg attcagattt
    11521 ttaatccatc tcgtttgacg agacagccat ttttggagaa ttgatccgct atctggacca
    11581 gtatgaggat gtgattctat gtgaaaataa gcgccattac cttaattttc ctacgcttga
    11641 atcacttgat agtcttgaac tggatcaaga gatttttgtc agagaagcta gtccggtcta
    11701 tcaagccttg ttggagcaga gttttgagac ggaattgcgc aatcaaatca atgcagctat
    11761 tttagttgaa aagacggact ttgcgcgcat taaaatgacc ctgtccaatt atttttacaa
    11821 ggtcaaacag cagtatcctt tgacagaaaa acagcaggag ctctatgaca ttttaggaga
    11881 tgttaatcct gagtatgccc tcaagtatat gacggctttt ttgttgaaat ttctcaaaaa
    11941 agaccagctt atgcagaaat gccgtgatat ctttgtggac agtttggttg tcttaggcta
    12001 tattgtgcaa aatgaagata gaaagtatga gttggctatc gattttgata aggagagatt
    12061 aactttctac ttagcgtgat ttcttgtttc tgagaacatt gtttgacttt ccttagtatt
    12121 cggtataaac tatatgtaac cggtaacaca tatcggaata aactaaagga gacaatcata
    12181 tgtcacttga aaacaaattg gaacaagcaa caggtgctgt caaagaaggt tttggtaaag
    12241 ttactggaga cagcaagaca gaacttgaag gagctgttga aaaaacagtt gctaaggcaa
    12301 aagacgttgt agaagacgca aaaggtgctg tagaaggtgc cgttgaaggt ttgaaaaacg
    12361 tttttactaa agaataggaa aaaatcaagg gtttcatttt cccttgattt tttctattct
    12421 tataaataat tttctgcgac ggctgtatct cctgggtagg attctttctt gccctggatg
    12481 atttggtaac aatcggctcc cttacccgca ataataactg catctaattc gtgatttgtg
    12541 atagccattg ccgccttgat ggcttcttgg cgatccgcaa tcttttcaac aggatgattg
    12601 atgtagctac taatttcatc tgcaatgacc attgggtctt catagttagg gtcatcagca
    12661 gtcagaaaga cttgaatctc agggtgttga ttgaggagga ggccaaagtc cttacgacga
    12721 ctttctccct tgtttcctgt tgatcccaga accagagcaa tctttccggt ttgatgagtt
    12781 tcaaccacat tgatgagttt tttcagacta tccccattgt gggcatagtc gatgaagacc
    12841 ttggctccat ttttctgagt gaggacttcc atacgaccag gaacgcgggt tgcagcgatg
    12901 ccttttttga tgtcctcaag acttgctccg agacggagac aagcaagtcc agcagcaact
    12961 gcattttctt ggttgaagtt gccaatgagt tgaatatcat aatctccagc gagtttaccc
    13021 gtagctgaaa agctaaaggc tttggaattc tcgatttggt tatcaaattg gctaccatag
    13081 aaatcatggt cttgatcttc aacctgttct ttcaagactg agaagtggtc catgtcactg
    13141 ttaatgatga ctgctcggct attttccatc aagagacgct tgtggtagaa atagtcttca
    13201 aagctagggt gttcaatcgg gccgatatgg tctgggctga tatttaggaa aactcccaca
    13261 tcaaaggtta gaccatagac acgtttgacc agataggctt gactggagac ttccatgatg
    13321 aggtgggtac ggtcattttg cacagcctga ttcatcatgt caaagaggtc aatactctca
    13381 ggggttgtca acgctgactt aaagaaagtc tcgccatcaa gagttgtgtt catggtcgac
    13441 aacatagcag gtctatgccc ttgagataag atgttatagg cgaaataggc tgctgttgtc
    13501 ttacccttag taccagtaaa ggcaaggagt ttgagttttt cctgtggatt accatagaac
    13561 tccatggcaa tcaaactcat ggctttcttt atatcgttca caatgatgac agggataccg
    13621 acttcgtagt ccttttcagc tacataccaa gctaatcctt gtgttatagc agaaagaagg
    13681 tattcttttt taaaggcagc gccttttgcg aaaaaaagag tgtcttctgt tacttttcgg
    13741 ctgtcgtagc tgatgctatc aaaaataact ttgctgtagt tgtagtggta atgaccttgg
    13801 tcaataattt cgcgaaaaag gccatctttc tttaaaatat ctaatacggt ttcaatctta
    13861 atcatacttt ctattgtaaa ccgaaagtcg taaatttaca agtaacaagg aaaagtttat
    13921 aatggaagat aaggagtttt tcctagctat caaaattgaa tgaggaatct atgtcgcacg
    13981 aaaacaatca ccagcaggcc cagatgttac gggggactgc ttggctaacg gctagtaact
    14041 ttatcagtcg cctactcggg gctgtttaca ttatcccttg gtacatctgg atgggggctt
    14101 atgcagctaa ggcaaatggt ctctttacca tgggttacaa tatctatgct tggttcttgt
    14161 tggtttcaac agcggggatt ccagttgcgg tggccaagca agttgccaag tataatacca
    14221 tgcgagaaga agagcatagc tttgccctga ttcggagctt cttaggcttt atgacaggac
    14281 taggcctggt ttttgcttta gtcttgtatg tctttgctcc ttggctagca gacttgtctg
    14341 gcgtgggcaa agacttgatc ccaatcatgc aaagcttggc ttggggagtc ttgattttcc
    14401 cgtctatgag tgttatccga ggatttttcc aagggatgaa taacctcaaa ccctatgcca
    14461 tgagccaaat tgctgagcag gtcattcgtg ttatctggat gctcctagca acctttatca
    14521 ttatgaagct cggttcagga gattatctag cagccgttac ccaatcaacc tttgctgcct
    14581 ttgtcggtat ggtagccagt tttgcagtct tgatttattt ccttgcccaa gaaggttcac
    14641 tcaaaagagt ctttgaaaca ggagataaga ttaacagtaa gcgtctcttg gttgatacca
    14701 ttaaggaagc cattcctttt atcctgacag ggtctgccat ccagctcttc cagattttgg
    14761 atcagctgac ctttatcaat agtatgagct ggtttaccaa ctacagcaat gaggacttgg
    14821 ttgtcatgtt ttcttatttc tcagccaatc ctaataaaat cacgatgatt ttgatttctg
    14881 taggggtttc gattgggagt gttggtttgc cacttttgac ggaaaactat gtcaaggggg
    14941 acttgaaagc agcttctcgt ctggttcagg acagtctcac cctactcttt atgttcttgc
    15001 taccagcaac ggttggagtg gttatggtag gagaacctct atatacagtc ttctatggta
    15061 agccagatag tttggctctg ggcttatttg tctttgcagt tttgcagtct attattttag
    15121 gcttgtacat ggtcttgtct ccaatgcttc aggccatgtt ccgcaaccga aaggccgttc
    15181 tctattttat ctatggttct attgccaagc tagtcttgca actacctacc atcgccctct
    15241 tccacagtta tggtcctttg atttcaacaa ccattgctct catcattcct aacgtcttga
    15301 tgtatcggga tatttgtaaa gtaactggtg tcaagcgcaa ggtgattttg aagcgaacca
    15361 ttttaatcag tttgctgacc ctagtcatgt ttctgttaat aggaaccatc cagtggctgt
    15421 taggattttt cttccaacca agtggacgtt tgtggagctt cttttatgta gctcttgtcg
    15481 gtgccatggg gggtggactt tatatggtta tgagtctgcg tacctattta ttagataagg
    15541 taataggaaa agcccaagca gatcgcctgc gagcaaaatt taagctttcg taaggtagca
    15601 tttataaata aaaggaataa gttgaacaat cttttaggag aacttgaagc ttattccttt
    15661 tttagcgtca aaatagctaa aattatcttt caaaaataga aaatgaggtt tttttgattt
    15721 tttggaaaaa acaattgact aaacaaacca agagttgtat aataaaacaa atatttaaag
    15781 caggaggttc tggaaatgaa aaagtctaag agcaaatatc taaccttggc aggtcttgtc
    15841 ctgggtacag gagttttatt gagcgcgtgt ggaaattcta gcactgcatc aaaaacctat
    15901 aactatgttt attcaagtga tccatctagt ttgaactatc tagcagaaaa ccgcgcagca
    15961 acatccgata ttgttgcaaa tttggtagac gggttattag aaaatgacca atatgggaat
    16021 attattccat cattagcaga ggattggact gtttctcagg acggtttgac ctatacctac
    16081 aaacttcgta aggatgccaa gtggtttact tctgagggag aagaatatgc gcctgtaact
    16141 gcccaggatt ttgtgacagg tttgcaatat gcagctgata aaaaatcaga agccttg
//
LOCUS       DAVLIK010000039        16178 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLIK010000039 DAVLIK010000000
VERSION     DAVLIK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16178
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.039"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            258..911
                     /locus_tag="VXE87_001525"
     CDS             258..911
                     /locus_tag="VXE87_001525"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0843052.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            921..1385
                     /locus_tag="VXE87_001526"
     CDS             921..1385
                     /locus_tag="VXE87_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0843053.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECATREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1398..2666
                     /locus_tag="VXE87_001527"
     CDS             1398..2666
                     /locus_tag="VXE87_001527"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0843054.1"
                     /translation="MLLIKNGRVMDPKSGLDQICDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2680..2940
                     /locus_tag="VXE87_001528"
     CDS             2680..2940
                     /locus_tag="VXE87_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843055.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2951..4312
                     /gene="pdrM"
                     /locus_tag="VXE87_001529"
     CDS             2951..4312
                     /gene="pdrM"
                     /locus_tag="VXE87_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0843056.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSPLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            4466..5434
                     /locus_tag="VXE87_001530"
     CDS             4466..5434
                     /locus_tag="VXE87_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0843057.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5450..6442
                     /locus_tag="VXE87_001531"
     CDS             5450..6442
                     /locus_tag="VXE87_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0843058.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6660..7703
                     /locus_tag="VXE87_001532"
     CDS             6660..7703
                     /locus_tag="VXE87_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0843059.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7767..9452
                     /gene="lpdA"
                     /locus_tag="VXE87_001533"
     CDS             7767..9452
                     /gene="lpdA"
                     /locus_tag="VXE87_001533"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0843060.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEEKGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9516..10505
                     /locus_tag="VXE87_001534"
     CDS             9516..10505
                     /locus_tag="VXE87_001534"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0843061.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10576..11646)
                     /gene="xerS"
                     /locus_tag="VXE87_001535"
     CDS             complement(10576..11646)
                     /gene="xerS"
                     /locus_tag="VXE87_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0843062.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSALENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(12221..13771)
                     /locus_tag="VXE87_001536"
     CDS             complement(12221..13771)
                     /locus_tag="VXE87_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0843063.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMSDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQILGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13787..14566)
                     /locus_tag="VXE87_001537"
     CDS             complement(13787..14566)
                     /locus_tag="VXE87_001537"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0843064.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14553..15404)
                     /gene="ylqF"
                     /locus_tag="VXE87_001538"
     CDS             complement(14553..15404)
                     /gene="ylqF"
                     /locus_tag="VXE87_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0843065.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15878..>16178)
                     /locus_tag="VXE87_001539"
     CDS             complement(15878..>16178)
                     /locus_tag="VXE87_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843066.1"
                     /translation="LIKNEVRMMMSCIAYNLYLFLKHLSGGDFQTLTIKRFRHLFLHV
                     VGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT         4798 a         3106 c         3470 g         4804 t
ORIGIN      
        1 tttctaaaga aactcctttt tctgaaatgg attttaatat gtttaaaaat atttcagaaa
       61 agataatctt cgaaagaggt agtaaaatgc ttaatgattt aaaaagtaat tataaaaaat
      121 agccagtctt tataaactgt attcacgtat tcaaatcgta tatagtcgat ttattaaatc
      181 tttagataaa ttgtaaaaag tggtttccat agccactttt tgctataata gaggcagtaa
      241 aaatgaagga gtcagctatg gaacactcgt cttggcatgc tttgattaag gcgcaattac
      301 ctgagggtta tttcgggaaa atcaatcagt ttatggagca ggtctattct caggggatta
      361 tttatccacc caaggaaaag gtttttcagg ctctcttgac aacactgctt gaagaagtta
      421 aggtggtaat tctagggcaa gacccctatc acggaccagg tcaagcgcag ggcttgagtt
      481 tttctgtacc tgactctatc ccagctccac catccttgca aaatatcttg aaagaattgt
      541 cagatgatat cggagttaag aaatctcatg atttgacagc ttgggctgag caaggagtct
      601 tgcttcttaa tgcttgtttg actgttcctg ctggacaggc caatggtcat gctggtcaaa
      661 tctgggagcc ttttactgat gctgtgattc aggtggtcaa tcatctagat agaccagtcg
      721 tttttgtact ctggggagct tatgcacgta agaagaaggc cttagttacc aatcctcatc
      781 acttgattat cgaatcagcc catccaagtc ctttgtcggt ttatagagga ttttggggtt
      841 ccaagccctt ttccaaggcc aatgcattct taaaagagac aggacaagag ccaatcgatt
      901 ggcttagata aggagaaaat atgcctcagt tagcgacgat ttgctacatt gataatggga
      961 aagaactgct catgctccat cgtaataaga aacccaatga tgtccatgaa gggaaatgga
     1021 ttggtgtggg tggtaagcta gagagaggag agacgcccca ggaatgcgcg acgcgtgaaa
     1081 tccttgaaga aacagggctc aaagccaagc cagttctaaa aggtgtcatc acttttcctg
     1141 aatttacacc agatttagac tggtacacct atgtttttaa ggtgacggag tttgagggcg
     1201 acttgattga ctgcaatgag gggacgctag aatgggttcc ctatgatgag gttttgagca
     1261 agccgacttg ggaaggtgac cacacctttg ttgagtggct tttagaggat aaacccttct
     1321 tttcagccaa gtttgtttat gatggggata aattgttgga tacccaagtt gatttctatg
     1381 aataaaggag aaagcagatg ctactaatca aaaatggtcg tgtaatggat cccaagtctg
     1441 gtttggatca aatttgtgat gtcttagttc aagatgggaa aattatcaaa attgcgcctg
     1501 agatcacgga agaaggagca gaaacgattg atgctactgg tcttgtggtt gctcctggtt
     1561 tggtcgatat tcatgtgcat ttccgtgaac ctggtcaaac acataaagaa gacattcata
     1621 ctggtgccct agcagccgct gcaggtggtt ttactactgt cgtcatgatg gctaatacca
     1681 gtccaaccat ttcagacgtg gagactttgc aagcagttct ccagtcagct gccaaagaga
     1741 agattaatgt caagacagtt gcgaccatta ctaaaaactt taatggtaaa aacttgactg
     1801 actttaaggc actcttagaa gctggtgcgg ttggtttctc tgatgacggt attccgcttg
     1861 agagcagtaa gattgtcaag gaagccatgg aggaagccaa aaaactcaat acctttatca
     1921 gccttcatga ggaagatcca ggtttgaacg gtgttcttgg ctttaatgaa aatattgcta
     1981 gagaacattt ccatatctgc ggtgctactg gggtggctga gtacgctatg atggcgcgtg
     2041 atgtcatgat tgcctatgca actaaagccc atgttcacat ccagcatttg tctaaggaag
     2101 aaagtgttaa agtagtggag tttgctcagg ggttaggtgc agaagtcaca gcagaagtag
     2161 cgccacagca tttctctaag acagaagcac ttcttttaac acaaggtagc aatgctaaga
     2221 tgaatccacc gcttcgtttg gaatcagacc gtcgtgccgt tatcgaaggt ctcaaatcag
     2281 gtgtcatcac agttattgcg actgaccacg cgcctcatca tgtagatgaa aaaaatgttg
     2341 aggatattac caaagcgcca tctggtatga ctggcttaga aacatccctg tctctcagct
     2401 tgacctattt agtagaagct ggtgagttga gcttgatgga attacttgaa aaaatgacat
     2461 acaacccagc caagctttac aactttgaag caggttactt ggctgagaat ggtccagcag
     2521 atatcactat ttttgatgcc aaggctgacc gctttgtgga ctcccatttt gcttccaaag
     2581 cagctaattc accattcatc ggtgaaacct taaaagggca ggttaaatat accatctgta
     2641 agggacaaat cgtctatcaa gcttgatagg agttagaata tgaattattt tcgaaaacgt
     2701 agggagagac aagcgaaatc taatagtgga atttactgtc ccgcagctaa tcgttccaaa
     2761 attcaatatg aaactaaaga aaaagctgac catgcggttc aatatgataa cggaggttta
     2821 gttagaagct attattgtcg tacatgtgcg tgttggcata ctacttcaaa atctaataaa
     2881 cctccgctaa gtttgaaaaa ctatggtctg aaactctttg gtttagataa atcagaatag
     2941 aaagagaagt atgtataaga caaagtgttt acgagagaag ttagtattat ttttaaaaat
     3001 tttcttccca atcctgatct accaatttgc caattattct gcctcttttg ttgatactgc
     3061 aatgacaggt caatacaaca ctatggactt ggctggtgta tctatggcaa ccagtatctg
     3121 gaatcctttc tttacatttc taacagggat tgtgtcagcc ttggtgccta tcattggtca
     3181 ccatcttggt cgaggcaaaa aggaagaagt tgcgtctgat ttttaccaat ttatttattt
     3241 ggccttgggc ctatctgtgg tcttgctggg gatggtactt ttcttggcac caataatctt
     3301 gaatcatatt gggttagaag cagcagtagc ggcagtagcg gttcgctatc tttggttttt
     3361 atctatcggg attatcccct tgttgctctt tagcgtcatt cgttccttgc tggattcgct
     3421 gggcttgacc aaactgtcca tgtacctcat gcttttgtta ctccctctca atagcggatt
     3481 taactatctc ttgatttacg gtgcctttgg tgttccagaa ctgggagggg ctggtgctgg
     3541 tttaggaaca tccttggcct actgggtctt gcttgggatt tctgttctgg ttttatttaa
     3601 acaggagaag ctcaaagcct tacaccttga gaaacgaatt ccacttaata tggataaaat
     3661 taaggaagga gttcgtttag gtctgcctat tgggggaact gtcttcgcgg aagtggctat
     3721 cttttcagtg gttggcttga ttatggctaa gttttcgccc ttgattatag ctagtcacca
     3781 gtcagctatg aacttttcaa gtcttatgta cgcctttcct atgagtatct catcggctat
     3841 ggctattgtc gtttcctatg aagtgggagc caagcgattt gatgatgcga aaacctatat
     3901 tggtctagga agatggactg ccctcatttt tgcggccttc accttaacct tcctttacat
     3961 ttttagggga aatgtggcca gtctttatgg taacgaccca aaatttatcg atttgacagt
     4021 gcgtttttta acttatagtc ttttcttcca gttagcagat acctttgcgg cgccgcttca
     4081 gggaattttg cgggggtata aggatacagt tattcctttt taccttggtt tgcttggtta
     4141 ttggggcgta gcaatccctg tggctacgct atttgattcc ctaacagatt ttggagctta
     4201 ttcttactgg atcggcttga ttattagttt gattgtgagc ggggcgctct accgttggcg
     4261 tttaactgtg attatgaaga gatttgaatc tttagcaaaa tccaaatgct aaaaagtttg
     4321 tgaaaaaata ttcttgacaa gaaaatccct tgttttcacg gggttttctt ttttattttg
     4381 tgaaatttct tttagaaaaa ctttgacagt atttgccaaa agcggtaaaa tagtaaggta
     4441 agaagaaagt tagaaaggca agaagatgtc aactttagat aaaaatcttt tgctagaaat
     4501 gttccgtaag atggaagaaa tccgtcgcat ggacttaaaa attgcacaat tagtaaagaa
     4561 agggaaagtg ccaggaatga cgcacttttc tgttggtgaa gaggcagcta acgtgggggc
     4621 tatgttagct ctcaatccag atgatctgat tacctcaaac caccgtggac acgggcaagc
     4681 tattgctaaa gggattgacc tcaacggaat gatggctgaa atccttggta aatacactgg
     4741 aacctgtaaa gggaaaggtg gatctatgca tatcgctgac cttgatgctg ggaaccttgg
     4801 tgccaatggt atcgtaggtg gtggtatggg gatcgctgtc ggtgcagccc tcagtcagca
     4861 aatgcaaaat accggtaaaa tcgttgtctg cttctttgga gatggtgcga ccaatgaagg
     4921 tgttttccac gaagcagtga acatggcttc tatctggaac ctgccagtca ttttctattg
     4981 cattaacaac ggttacggta tctctgcgga tatcaagaaa atgaccaata tagaacatat
     5041 ccatcaacgt agcgccgctt atggaattcc tggaatgttc atcgaagacg gtaacaatgt
     5101 catcgatgtc tatgaaggat ttcagaaagc tgtggaccat gttcgcagtg gcaatggtcc
     5161 agtcttgatt gaaagtgtaa cttatcgctg gctcggtcac tcatcatctg accctggtaa
     5221 atatcgtacg cgtgaagaag tggaattgtg gaaacaaaaa gatccaatcg aaaacctccg
     5281 caattacctt attgaaaata acattgcaag tgccgaagaa ttggaagaaa tccaagcgca
     5341 agtaaaggaa gcagtagaag cttctgttaa atttgcagag gaaagcccat tcccaccgct
     5401 tgaatcagcc tttgaagata tttacgcaga ctaaggagaa agagataaaa tggaaacaaa
     5461 aacaatgtcc ttccgtgaca ccattatcct tgctatgtct gaggaaatgc gtcgcgatga
     5521 aaatgtgttc ttgatgggag aagacgtcgg tgtcttcgga ggagacttcg gtacttctgt
     5581 tggaatgctt gaagaatttg gtccagaacg tgtccgtgac tgtccgattt ctgaagctgc
     5641 catctctgga gcagcagcag gagcagccat gacaggactt cgtccaatcg tcgatatgac
     5701 cttcatggac ttctctgtta ttgccatgga caatatcgtc aaccaagctg ctaaaacacg
     5761 ttacatgttt ggtggtaaag gtcaggttcc aatgactgtt cgttgtgcag ctggtaacgg
     5821 agttggctct gccgcccagc actcacaatc tctagagtct tggtttactc acattccagg
     5881 acttaaggtt gtggcacctg gaacacctgc ggacatgaaa ggcctgctta agtcttctat
     5941 ccgtgataac aacccagtta ttatacttga gtacaagtca gaatttaacc aaaaagggga
     6001 agtgccagtt gatccagact acacaattcc acttggggtt ggtgaaatca aacgccaagg
     6061 gacggatgta acagttgtta cttatggaaa aatgcttcgc cgtgtggttc aagctgctga
     6121 agaattagca gaagaaggaa tttcagttga aattgttgac ccacgtaccc ttgttccgct
     6181 tgataaggat atcatcataa actcagtgaa gaagactggt aaggttgttc tggtcaacga
     6241 tgcccacaaa acaagtggct atatcggtga aatttcagct attatttcag aatcagaagc
     6301 atttgactat ctagatgcac caatccgccg ttgtgcagga gaagatgtgc cgatgcctta
     6361 tgcacaaaac ctagaaaatg caatgattcc aacagttgaa agtatcaaag atgcaatccg
     6421 aaaaacttat aacaaagact agagttacat aagataagtt atgtaaataa aacaaagctg
     6481 acgagaaact ttgtatcttt taggtgcaga gctcttcgtc attaatatct tagattagag
     6541 cacgggctaa aagctcggaa aaaagataaa tctccttggc ttcatcgaag ccatcgtcga
     6601 tttcctattt ttcagtcgct tttgacgccc tttgtatcat aaatagaatt ggagaggtca
     6661 tggctgatga caagctaaga gcgactcctg cagctagaaa gttagcggat gatttaggga
     6721 taaacctcta cgacgtttct ggctcaggtg caaacggtcg tgtccacaaa gaagacgtgg
     6781 aaacttataa agacacaaac gtggttcgca tttcgccact tgcaaaacga attgccctcg
     6841 aacataacat tgcttggcag gaaatccaag gaaccggtca tcgtggtaaa atcatgaaga
     6901 aggatgtttt ggccctgctt cctgaaaata tcgaaaacga tagcatcaaa tctcctgctc
     6961 agattgaaaa agtggaagaa gtccctgata acgtaacacc atatggtgaa atcgagcgta
     7021 ttccaatgac accaatgcgt aaggttattg cccaacgcat ggttgaatct tacttgactg
     7081 cgccaacctt caccctaaac tatgaagttg atatgactga aatgttggct cttcgtaaga
     7141 aggttcttga gccaatcatg gaagcaactg ggaagaagac tactgtaaca gaccttcttt
     7201 cacttgcagt tgttaagact cttatgaaac acccatacat caacgcttca ttgacagaag
     7261 atggcaagac tattatcact cacaactatg tcaatcttgc catggcagtt gggatggata
     7321 atggattgat gacacctgtt gtttacaatg ctgagaagat gagtctttca gaactggttg
     7381 tagcctttaa ggatgttatt ggtcgtacct tggatggtaa attggctcca agtgagttac
     7441 aaaattcaac attcacaatc agtaatttgg gaatgtttgg tgttcagtcc tttggtccga
     7501 ttattaacca acccaactca gctatccttg gtgtcagttc gacaatcgag aagccagttg
     7561 tcgtcaatgg tgaaattgtg attcgcccaa tcatgagttt aggattaacc attgaccacc
     7621 gtgtcgtaga tggtatggct ggtgctaagt ttatgaagga cttgaaagag ttgattgaaa
     7681 cgccaatctc aatgttaatt taagagcaag agtattcatt tttaagatat agataaagga
     7741 aggaagacat ggccttagaa gtaattatgc caaaagccgg cgtggatatg acagaaggac
     7801 aaatcgtcca atggaataaa aaagtcggag aatttgtaaa agaaggagaa atccttttgg
     7861 aaatcatgac tgataaagtc agcatggaat tggaagccga agaagatggg tacttgattg
     7921 ccattctcaa aggagatggt gaaactgtcc ctgtaacgga agttatcggt taccttggtg
     7981 aagaaaggga aaacatccca acagctggag cagcatcgcc agaagctagc cctgtacctg
     8041 tagcaagtac ctcaaacgat gatggtaaga gcgatgatgc ttttgatatc gttgtgattg
     8101 gtggaggtcc tgctggttat gttgcagcca ttaaagctgc ccaactcggc ggtaaggttg
     8161 cccttgttga gaaatctgaa cttggtggaa cctgcttaaa ccgtggatgt attccaacca
     8221 agacctacct tcataacgct gaaattattg aaaatatcgg tcatgctgca aatcgtggta
     8281 tcgtgattga aaatcctaac ttcactgttg atatggaaaa acttttagaa actaaatcta
     8341 aagttgttaa tactcttgtt ggtggtgttg caggacttct tcgtagctac ggagttactg
     8401 ttcataaagg aattggtaca atcactaaag acaagaacgt cttggtaaat ggttctgaat
     8461 tgcttgaaac caagaaaatc attcttgctg gtggttcaaa agtcagcaag atcaacgtcc
     8521 ctggtatgga atctccactt gtcatgacta gtgatgacat tcttgaaatg aacgaagtgc
     8581 cagaaagcct tgttatcatc ggtggtggag ttgtcggtat cgaactcggt caggccttca
     8641 tgacgtttgg ttcaaaagtg actgttatcg aaatgatgga ccgtatagtt ccagctatgg
     8701 atgcggaagt ttctaagaac cttcgcttga tccttgagcg taaaggaatg accatcttga
     8761 ctggtactaa actgcaagaa atcattgagg aaaaaggtca acttcgtatc aaggttgaag
     8821 gaaaagacga tatcatagca agcaaagctc ttctttcaat tggtcgtatg ccagaccttg
     8881 aaggtattgg agaggttgag tttgaattgg atcgtggttg tatcaaggtc aatgaataca
     8941 tggaaacttc agttccaggc atttatgcac caggtgacat caacggtact aagatgttgg
     9001 ctcacgcagc tttccgcatg ggtgaagttt ccgctgaaaa tgcccttaaa ggaaatcatg
     9061 cagttgccaa attgaatttg actcctgcag ccatctacac tctccctgaa gtagcagcag
     9121 taggtttgac agaagaacaa gcccgtgaga aatacgatgt tgccatcggt aagtttaact
     9181 ttgctgctaa tggtcgtgct attgcatctg acgcagctca aggtttcgta aaagttatcg
     9241 ctgataagaa atacggagaa atccttggtg tacacattat tggtcctgca gccgcagaat
     9301 taataaacga agcatcaagc atcatcgaaa tggaaatcac tgttgaggaa atgctgaaga
     9361 ccatccacgg gcacccaact tactctgaag tgatgtacga agcgtttgca gatgttctag
     9421 gaatggccat ccattcacct aagaaaaaat aaaacgaaga tagattagac tggaaggtta
     9481 tttccagttt ctatcatata aagtaaaggg atatcatgaa atacattatc aatcattcaa
     9541 atgacactgc ttttaatatt gccttggaag aatacgcctt taaacacctt ttggatgagg
     9601 atcaaatctt cctactttgg attaacaagc catctatcat tgttggtcgt caccagaaca
     9661 ctatcgaaga aatcaaccgt gattatgttc gcgaaaatgg tattgaggta gttcgccgta
     9721 ttagtggtgg tggagctgtt taccacgatt taaataacct caactacacg atcatctcca
     9781 aagaagatga aaataaggca tttgacttca agagcttctc aactccggtt atcaataccc
     9841 tggctcaact tggggttaaa gctgagttca caggtcgtaa tgaccttgag attgatggta
     9901 agaagttctg tggtaatgcc caagcctata tcaacggccg tatcatgcac cacggttgct
     9961 tgctctttga cgttgatttg tcagtcctcg caaatgccct taaggtttca aaagataaat
    10021 ttgaatcaaa aggtgtgaaa tccgtccgtg cccgtgtaac caatattatc aatgaattac
    10081 caaaaaaaat cacagtcgaa aaattccgtg atttactctt ggaatacatg aaaaaagagt
    10141 acccagagat gactgaatac gtcttttcag aagaagaatt ggccgaaatc aatcacatca
    10201 aggatactaa gtttggaact tgggactgga actatggtaa atcacctgaa tttaacgtcc
    10261 gtcgtggaac caaattcact agtggtaagg ttgaagtctt tgctaacgtt actgaatcaa
    10321 aaatccaaga catcaagatt tatggtgact tctttggtat tgaagacgtt gctgcagtag
    10381 aagatgtcct tcgtggggtg aaatacgaac gcgaagatgt tcttaaggcg ctaaaaacca
    10441 ttgatatcac acgctacttc gctggtatta gccgtgaaga aatcgctgaa gcggtagttg
    10501 gataaatcaa aaagaagttg gccaactaac caacttcttt ttgatattta tttacataat
    10561 ttaaaatacg taaaattata aactatctag agcattcttt tgttcatcat taacaatatg
    10621 ggtatagagg tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg
    10681 tgatttagtc gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac
    10741 acgcacttta aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat
    10801 acgattagga acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt
    10861 atagcgttga ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac
    10921 attgactgag tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt
    10981 gagatctctt agatctagat taacagcttc agataagcga acaccagatg ccaagagaag
    11041 ggcaataatg gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga
    11101 aagctgttgt gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag
    11161 aaagagtttt tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt
    11221 tgaaactttt ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc
    11281 ctcggttaga tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg
    11341 tgaaacacct tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat
    11401 aaaggattcc atgtctttct tagacatatt ttccaaagct gataaaggaa tatcggatat
    11461 tttatcagcg tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt
    11521 aaggtattcg tacagggttg taaaactgta gggtacagcc agcttagatt ggtagtattc
    11581 cagaacatac cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg
    11641 tttcatgtat tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt
    11701 tcaagaaaat tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga
    11761 cttagaccta caaacaaaac agaataagga aaatctcacc cactaaactt ctgttaatac
    11821 tacataactg aagagctata taaggagcta tgagatacaa aacacattgt ataatagatt
    11881 gaaactagaa tagtacatct ggacttctaa aacattgcta gaaattgatt tgattgtcct
    11941 gattgtttta tcctatttct atttcatttc actatataat tgctattgtt ttctttttca
    12001 tgattttaat cttactgtac agatttgata cagtaaactc ctttccagct ttatgcttta
    12061 tcatttctaa cttaattata gtcttatttt taataaagtt caattattta tatgtaaaat
    12121 tcctcatcag taaaaaataa ccgatctcat ttctgagaat cggttttcta aataaatcaa
    12181 actgatcatt tacataacat aaattatgtg aatgatcata ctacaacaac aaatctttga
    12241 cttttccaat ttcacttttt ggaataacca ggtgaatcat atcacccaga tacattctgg
    12301 ttgagccgtt aactgtttgg ctcttgccat tatggacttg agttgtgatg aggacgttgt
    12361 gtggtaagtt gagttcatga acttgtttcc cagcaatttt atcagaaact ggtatttcga
    12421 taagtgtaac ttctccttcg ctagatactt cttctggaag cattttttcc agcatggctt
    12481 catagactgg cgtacctttg agcaaatcca tgataatata agaaacaaga gtgacaagac
    12541 caagtggcat gaggttgcga atatctccta ccatctcagt tacgaggatc atagcggtta
    12601 agggagcttt tgatatggct ccaaaatagc cactcattcc tagaatgaca aatataggga
    12661 attgctcttg actgacaagt ccaagattga cacagataac accaactaag gcaccaagca
    12721 aagaaccaag agctaaaatg ggtaggaaaa ttcctcctgg cagtccactt ccatagctaa
    12781 tcatactcca aataaagcgg atcaaaaagt aagctaataa aacttggaaa ctaaaatttt
    12841 gttcagttaa agaaaggaca agctgatttc cgccaccaag gatttgaggt aagaagattc
    12901 cgactggtat gataaggata aaagccaaga tgggataata agccctatcc aaatggattt
    12961 tttgaccaat caagtcataa actcttccaa cgtttaatac agctttctca tagagaaaac
    13021 ctgaaaatcc aaggaaaatt cccatgacga gatatatcca atactggtct agggtcatgg
    13081 gaggaatgtt atctgacata tccaatactg gtgtcaaacc gaacatgagt agagacacaa
    13141 agtttgctac gatgctggct gctagagttg agacccagaa aaagcgcgaa aaatggtgat
    13201 agacttcttc tacaacaaag agaagtgctg caataggagc attaaaggct gcggctaaac
    13261 ctgctgcagc tccactggca atcaaggaac gttcctctac tggactggat ttgagccact
    13321 tggcaattcc tttaccacca actgctccaa gttgaatgct gggtccctct cgacccagca
    13381 tgagtccact ggcaatagca agaataccta gcacatattt tttccaaaga atgccccacc
    13441 agttgaggga catgaggcct ttcagttcgg cttcgacttg aggaattcct gagcctttaa
    13501 tatctttttc tgaccgtgtt agtttggcac tgagccaaca gatgagtata taaaacaaaa
    13561 ccagtacaaa aagattgcgc actaagtacc cttgatcttg ataaactcct tgtatcaggt
    13621 ggaagccctt ttcaattaag aaacgaaagg atccgacgat aattccaacg atgaggccga
    13681 caatgattcc tcgaccaact tgggatagta tagtgctgga tgcaaaggcg aattctttct
    13741 tagaacggac tatttccgac tgttcctcca tggtatttcc tttcaattaa ctttcttttt
    13801 tacctaaaac cagtgattta acgggttcaa agctggttcg gtgaattggg gtaactccta
    13861 gttttgtgag gccttccaga tgtttagctg tgccatatcc tgcattagta gcgaaatcat
    13921 agccagagaa ctgctgatcg tattctttca tcaattcatc acgtgttacc ttggctacta
    13981 tagatgctgc tgcgatagag agggagttgg catctccttt gataatggag gtttgtgaaa
    14041 tgggcaagtc cagtttcatg gcatcaatca aaaggtgctc tggttgaggg ctgagctggg
    14101 agattgcttc ttgcatggct agtttggttg cttcatagat gttgacttgg tcgatgacct
    14161 gattatctat gataccaatt ccaatcgaca aggcttggtc ttgaacggct tggaaaatct
    14221 ccagatgttt ctttttagga attttcttgc tgtcgttgag acctttaatc ttacaatttt
    14281 taggtaaaat aacggccgca gcgactacag gaccagcaag aggaccacga ccaacctcat
    14341 caatacctgc aattaaggtc aatccttgct tataaagttc tttttcataa gaaagcatgg
    14401 attccaagcg caaattttca tctaattcag cttgaatggc tcttttacgc ttgctgattt
    14461 ccttttgaac tcctgagcga ttatcctttt caagatctaa aaaaataggg ctttctaact
    14521 ccttgactgt cacaaggagt tctttgattt ctttaatcgt tgccatcgag gtcttccaat
    14581 gtatctaagg tatagttacc gagtttgcca tcacggactt ccttcacgaa gagactgtaa
    14641 aaacggtcat agtcatcacg gaaaccgagg gcgcgggtca tatccataat aatcacaggc
    14701 gcttcttctt caattttcat ttgtttgaag cgttcagcca gcttttctgg ataatgttct
    14761 ttgaaataat tgataccaaa aatggtaacc tcatccatag gaagcaactg atccttgata
    14821 gctccagtca atgccaactt aagtgcaaca gtttcatcct caaacttagg ccagagaatc
    14881 cccggtgtat ccaagatttc cagatcttta ttggttttaa gccattgttg accttttgtg
    14941 acccctggct tgtttccaac aacagcaatc tttttaccag ccaaacggtt catcagagtg
    15001 gatttaccag cgtttggaat cccgataatc atggtacgca aggtttcaat ctgaatccca
    15061 cgttctttct ggcgagcaat cttatcagcc atgagcttct tggccgcatc tgttacaact
    15121 tttacagtca cttgctcttt ggagttgata gctagcgtct ggattccttg tgattcaaaa
    15181 tactgacgcc attccttggt cattgctgga tcagccaagt cggccttgtt taaaatcaag
    15241 agttttggtt tatcaccaac aatcttggtc aacataggat tttgactaga tagaggcaag
    15301 cgtgcatcta ctaaaatcgt cacaaaatca acaaatttta aattctcctg cacctgtcga
    15361 cgagctttag acatgtgacc aggaaaccat tgaatagtag ccattgagtt ttttcctttc
    15421 atagcaagga tttagatccc ctattttatt ttactatagt ttgaacatag agagttttca
    15481 aatgaatgat gtccaaacag ttcttgtttt atgacataga aatctacttt atattatatc
    15541 atgccttctt tattttgtcc gatgatagcc ttttacccta tcttttaccc tataccctat
    15601 cctataccct atatagaaaa aagccatcaa atgatgactt ttcagaggga gcaaaaaact
    15661 gtcctcttta tgttttaaac atttaaccca aatcattcat acctctctca actagatgta
    15721 acttacaaaa cccctgacct catgagccac tttcttcctc ctcatgaggt cagttttact
    15781 ttctgctgtt ccagtatcgt ttttcctcgc tagatttcct caaaagagca gactcctccc
    15841 ttggtgcgtc acacgatttt ttcatctcga ctgttcttta atgcatcatt aacgacgctt
    15901 ttcttctagg tggttcataa ggaacaggaa gattcaggtt gacttttcta atcctagaat
    15961 aaagtgctga aaacaattcg gaataggcat agagactaga caatttgagg agctgcttgc
    16021 gtcctgttcg aacacatttt cctaccacgt gaagaaaaag atggcggaag cgtttgattg
    16081 ttaaagtttg gaagtcacct ccagatagat gtttgagaaa aagatagaga ttgtaggcga
    16141 tacagctcat catcatacga acttcgtttt tgattaag
//
LOCUS       DAVLIK010000040        15873 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLIK010000040 DAVLIK010000000
VERSION     DAVLIK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.040"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(236..328)
                     /locus_tag="VXE87_001540"
     CDS             complement(236..328)
                     /locus_tag="VXE87_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0843067.1"
                     /translation="MMELILKTIIGPIVVGVVLRLADKWLNKDK"
     gene            complement(551..640)
                     /locus_tag="VXE87_001541"
     CDS             complement(551..640)
                     /locus_tag="VXE87_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I addiction module toxin, Fst family"
                     /protein_id="HEV0843068.1"
                     /translation="MVDYIFTNIILPLVVGIVLIVIEKWLNKK"
     gene            complement(864..1103)
                     /locus_tag="VXE87_001542"
     CDS             complement(864..1103)
                     /locus_tag="VXE87_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843069.1"
                     /translation="MTFKEYLLKASKRDIYDDGKDFDFETIFAREILRYAHDSELETK
                     TGFFRHLEIMNADSWFVELARSIYQDFEKSISDSH"
     gene            1168..1359
                     /locus_tag="VXE87_001543"
     CDS             1168..1359
                     /locus_tag="VXE87_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0843070.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            complement(1542..1733)
                     /locus_tag="VXE87_001544"
     CDS             complement(1542..1733)
                     /locus_tag="VXE87_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843071.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTVELLEKYHEWLHS"
     gene            1852..1995
                     /locus_tag="VXE87_001545"
     CDS             1852..1995
                     /locus_tag="VXE87_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843072.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            2074..2346
                     /locus_tag="VXE87_001546"
     CDS             2074..2346
                     /locus_tag="VXE87_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843073.1"
                     /translation="MEVVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            2343..2537
                     /locus_tag="VXE87_001547"
     CDS             2343..2537
                     /locus_tag="VXE87_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843074.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            2534..2725
                     /locus_tag="VXE87_001548"
     CDS             2534..2725
                     /locus_tag="VXE87_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843075.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            2737..3078
                     /locus_tag="VXE87_001549"
     CDS             2737..3078
                     /locus_tag="VXE87_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843076.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYFNHTQALTELVDWKNDTRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            3079..3309
                     /locus_tag="VXE87_001550"
     CDS             3079..3309
                     /locus_tag="VXE87_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843077.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            3323..4045
                     /locus_tag="VXE87_001551"
     CDS             3323..4045
                     /locus_tag="VXE87_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0843078.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGVSLTEKQIKSYRRNNNLHSGLTG
                     RFEKDQTPHNKGKKYPNMPKNSGQFKKGNRPPNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            4038..4520
                     /locus_tag="VXE87_001552"
     CDS             4038..4520
                     /locus_tag="VXE87_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEV0843079.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQAAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNENDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELIRTEKLVIK
                     "
     gene            4520..4879
                     /locus_tag="VXE87_001553"
     CDS             4520..4879
                     /locus_tag="VXE87_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843080.1"
                     /translation="MELMNKTRVTDSLAVVIGLESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            4879..5364
                     /locus_tag="VXE87_001554"
     CDS             4879..5364
                     /locus_tag="VXE87_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843081.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNEKSKDNSVAETIAYIQLCYPEAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            5327..6520
                     /locus_tag="VXE87_001555"
     CDS             5327..6520
                     /locus_tag="VXE87_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEV0843082.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            6539..6856
                     /locus_tag="VXE87_001556"
     CDS             6539..6856
                     /locus_tag="VXE87_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843083.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            6856..7632
                     /locus_tag="VXE87_001557"
     CDS             6856..7632
                     /locus_tag="VXE87_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0843084.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYVNH
                     VDDKAILKILATIRGAVEPAKTEKTKEAPKKEVASDDELF"
     gene            7652..8155
                     /locus_tag="VXE87_001558"
     CDS             7652..8155
                     /locus_tag="VXE87_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843085.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKDLNWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEAQPLTEADI
                     DDDDLPF"
     gene            8328..9149
                     /locus_tag="VXE87_001559"
     CDS             8328..9149
                     /locus_tag="VXE87_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEV0843086.1"
                     /translation="MSSMKEYALQYQKLGFSVIPINPKNKMPLIDFADKPAMTPSEIE
                     NFWDGYPNANIALKITNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKDLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            9152..10495
                     /locus_tag="VXE87_001560"
     CDS             9152..10495
                     /locus_tag="VXE87_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0843087.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFFNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQKEYLKDKTGER
                     RFLPIMADSKQQKKHPMEIDPDTIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKNTKGFVRVKNSEKTNR"
     gene            10788..10940
                     /locus_tag="VXE87_001561"
     CDS             10788..10940
                     /locus_tag="VXE87_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843088.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KMEEME"
     gene            10940..11278
                     /locus_tag="VXE87_001562"
     CDS             10940..11278
                     /locus_tag="VXE87_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843089.1"
                     /translation="MSYDLEILAKIESGDYICIAEPRYSSPTYNLGKMFRVAMDWDFD
                     QGTIYNVADIFENIKRGITELERQPEKYVQYEPANKWGTINDALYVLRSLRDCILEQD
                     IDTKYLYVRW"
     gene            11429..11743
                     /locus_tag="VXE87_001563"
     CDS             11429..11743
                     /locus_tag="VXE87_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843090.1"
                     /translation="MEELKRKVNTVYNWTVEDGKPQPPKQDLPQVVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWVGYSPSMAQVVIAVYLIYR
                     GN"
     gene            11745..12272
                     /locus_tag="VXE87_001564"
     CDS             11745..12272
                     /locus_tag="VXE87_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0843091.1"
                     /translation="MNKQELIKKLEERRTITGNFQGYVVWWKDVKEIFEQLGEPQPVK
                     VPQFVADWIRKCKMFKHFAVSLSFALQPIVWEENGLSHECIEWLMDANNQELFALAWL
                     NGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELEDANF
                     GWVFDCEGIDIEEVE"
     gene            12334..12651
                     /locus_tag="VXE87_001565"
     CDS             12334..12651
                     /locus_tag="VXE87_001565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0843092.1"
                     /translation="MRYFKILCIVLFASLLVACHQISSGTVVDKYIDEPHTTFIPVIN
                     GKSSVLVPTRTKRKYILVVSGYAGNKQVEERFEVTANEYKHYEIGNTFIQDAVLENKE
                     EDK"
     gene            12769..13191
                     /locus_tag="VXE87_001566"
     CDS             12769..13191
                     /locus_tag="VXE87_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0843093.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWIDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRLINKLKNPKSRSILRVTYITK
                     MYVDDICDKMEISRTTFYTWRNMAISELNEVLERMELN"
     gene            13277..13359
                     /locus_tag="VXE87_001567"
     tRNA            13277..13359
                     /locus_tag="VXE87_001567"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13308..13310,aa:Tyr,seq:gta)
     gene            14461..14973
                     /locus_tag="VXE87_001568"
     CDS             14461..14973
                     /locus_tag="VXE87_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0843094.1"
                     /translation="MAFFDCLKGGDGKLNERQRRFADEYIISGNAYQSALRAGYSEKY
                     AKARSSELLDNVGISDYIKNRMEELQDEKILTQKQILVMLSEIASGQAKETIVVTTKV
                     AELMTDPVTGKSVKVYNEIPQLVEYPTKNSDRNKALELLGKRHKMWTDKVEADVSGTV
                     VFANESDISD"
     gene            14951..>15873
                     /locus_tag="VXE87_001569"
     CDS             14951..>15873
                     /locus_tag="VXE87_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0843095.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETSRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLIT"
BASE COUNT         5537 a         2594 c         3477 g         4265 t
ORIGIN      
        1 tttatagttt tattagtgtt tttgttatga ttttatttta gactttatta tagactttgt
       61 caataaaaaa gtacaaaaaa tagttacatt tttagttgtt tcttgtttac ttgttccttg
      121 acaattgaat agagcatgtg agataataaa ggggaattaa ggattagttc tatatcatgg
      181 actagaaaag accccaggct aacttccaca ttaagcttgg ggtctttttt tgacactatt
      241 tgtccttgtt cagccattta tcagctaaac gaagaacgac accgaccaca atcggtccga
      301 tgatagtttt aaggattagt tccatcatgg gctatctcac ctcctttcgt aggcggtgta
      361 gaagtgccgt aaaatattat accacatttc taattcagct tgtcaaaggt ttcttttgac
      421 aacttaaaat agatgtgaga taatataggg gaagtgaaga tgtagtctac tacaactaca
      481 aaaaagcccc tgctgataac cacaaaagca agggcttttt ctagtctacg ctagaaaggt
      541 gggttagtcg ctatttcttg tttagccatt tttcgatgac tatcaggacg ataccgacca
      601 ccaagggtag aataatattt gtgaagatgt aatctaccat aggctccacc tcccttctaa
      661 ggcagatgtg ccgtcactat tataccacat gctctatcag ttagataggg cattttttat
      721 ttttgaaaaa aggaggaacg tgtcgatggt aagtattctt aaaaatttag aacaagaaaa
      781 agaccacctt gaaaaaatca ttaaggtagt cagcgctggt ggtaaatttc tgagattgcc
      841 atatcaaaaa aagtcacgct cgattagtga gaatctgaaa ttgatttctc aaaatcttga
      901 taaattgagc gagcaagttc aacaaaccac gaatcagcat tcatgatttc aagatgacga
      961 aagaaacctg ttttggtttc cagttcagaa tcgtgtgcat aacgtaatat ttctctagca
     1021 aagatggttt caaaatcaaa atctttacca tcatcgtaga tgtcgcgttt gcttgctttg
     1081 agtaaatatt ctttaaaagt cataaggtta actcctttct gcttatatta tagcagaaaa
     1141 agaagaaaga aaaagaaagg agaaaatatg ccagatattg caaacggtcg cgaaagagtt
     1201 attgctttct tgaaagagaa aggcattaaa aaagcaactc tagcggttgc ttacggcttt
     1261 aaacgacagg aagtgacaaa cattctaagt ggaacgacta aaggtccacg agcgaacagt
     1321 ttcattcttc aggttattga agattatggg attgagtagg aaagatttga ggagtaggaa
     1381 aatgagacca agacgatatc cgtatagtgg gaaaaaagag tccacctttg taaaggccga
     1441 ccctgagtta gttgaaaaac ttttaagaaa cactagtttt cttgagtgtt tacaaaaaaa
     1501 gcctatcaat tttcagatag acttagaaga atttaagcgt cttagctatg aagccattca
     1561 tgatacttct caagtaactc aacagtagtt attacagaag tcaaaccact gaccttcccc
     1621 agttgcaatc cgtctgtatg gtcaatctgt ttagtagctt cattagcttt agcagagata
     1681 gcttgcatat cttcagctgt taaagattct cgaaaatctt taaaggattt cataaaaact
     1741 cctcctttct attggaattt tgactaaaac ggtgagaggt cctagtcgag attattatag
     1801 caatttagga ggatattaca tcggtcttga ggctgatttt tggaggcaat attggaagat
     1861 aaaatcatag aacttgctga ttacttcatc agcgaatcta caacgtacag agaagcaaaa
     1921 atagcgtgtg agaagctatt gaaacaagtc agccatgaga tagaactcag ggcgatggaa
     1981 agtaggacag tctagaagac aacaaaaagc acctgacgga aatcaggcgc atacttaaat
     2041 attcaacatg attataacac gaaaggagca aaaatggaag tagttgaaat tgtaagaatt
     2101 aaagatgtga ttattgaaaa agtctctgct aatgatgaag agttaaaacg tatctttgga
     2161 tgttcaaaac gacaagcagg agagcgaaga agagaaatgc aaaaactccc tagtcagcaa
     2221 aaacatcttt tggatagtgg acaacttgta acgattaaag gtttctatga atacttgcaa
     2281 tatcgtggaa ctaaagcttg gaaaaaagaa atggaaacaa gcaagaaaat gaggtcagca
     2341 ggatgaacct actatcaaga atcaaaaact atttttcgga agaggtcaaa gaaactaatc
     2401 tcgactggaa agaggtcgct ttagacctca atcaatcact aattgaaaca caggaaaaac
     2461 ttcaagaagc gaatcaagaa atcgcagact tgaagaaaat cgtagcaatc tacaaagaaa
     2521 aggagaaaga aaaatgatgg aatacattta cctggtaata atcgtaggaa ttggactatg
     2581 gtcgctagta aataaactag atgaccacgc tgaaatgaaa caaaaagagc gccagctgat
     2641 ggcaaacaat gtcgcacgga tgaatctgag aaattcagat aagcaattta cttatgatgt
     2701 agaaccgcct gaagggttga aataaggagg agaaacatga ctcaagcgga acaaattagg
     2761 gaatattata gagagcaccc tgctgcctca tgtgatgaag tggctgaggt tgtcggtaca
     2821 acaaaaagca acgtaagtgc aaacctggcc aaagacatca aggcaggcag atgcgttcgc
     2881 ttggaagaca agtcatacga ctactcccct tactttaatc acacacaagc gctcactgag
     2941 ttggttgatt ggaagaatga taccagacgt gagtgggtgg atatgctgac aagagcagca
     3001 gagaaagaaa cggatagcaa cgttatgcgt ttgttaatca aagaagcaaa taaattgatg
     3061 aaagaggtga ctaagtagat ggtacgaaat aaaataggtg atttaactaa cacgctcttc
     3121 gctcaattag agactctgga tgatagggat cttacagcag atgaattaaa agtagaatta
     3181 cagcgctcga aacaaatggt cgcaatctca ggtcaaatct tacaagcagg tcaattggcg
     3241 ctagatgctg aaaaattcaa agacaaggta ggtgaagtca atgccccgat cgctttgctg
     3301 gaaggatgag tacacggagt acatgcatga aatatgccct ggtcgtttaa ctcctgaagt
     3361 aaccaggttg ctgaatgaaa aatttggtac gaattataac aagagtcaaa tcggtggcgt
     3421 acgcaaacgt ctagggttag cagttggaaa agtctatcaa ggtcgattgc tgacaaagga
     3481 gcaacatgat tatcttgtat tgatccaaaa aaataagatt tctcgtaatg tcgcaaatga
     3541 aatgaaccaa aaatttggcg tatcgctaac tgagaaacag attaagagtt atcggagaaa
     3601 taataatcta catagtgggt tgacgggaag attcgagaaa gatcagactc ctcacaataa
     3661 ggggaagaag taccccaata tgccaaaaaa cagcgggcag ttcaaaaaag gtaatcgacc
     3721 tccgaattat gtacctgtcg gcactatcaa ctacacaaca gacggttatc caaaagaaaa
     3781 gattggagaa cctaatcaat gggttttgaa acatcgtaaa gtctgggagg accatcacgg
     3841 gctgatacca aaagggtact caatcgtttt tctggacggt gataaaacaa actatgatat
     3901 ttcaaatctg gcatgtttat ctaagaacga aattgctaga atgaatcaaa atcatttatt
     3961 cacgtccaac gctgatttga ctaaatcagg tattggacta acaaaactta caaataaaat
     4021 cagagaggta gaaaaaaatg gctagtttat acgaactaac aggtcagttc ctgacaattt
     4081 accaattgga tatcgatgac gaaacaaaag cagacacgct tgaggccatc gattggcaag
     4141 aacaatttga acagaaagca gaaggatatg cccatgttat caagaatcta gaagccgacg
     4201 tggccatgta caaagctgag gaagagagct tcaaagccaa gaaacaagcg gcacagaaaa
     4261 agctggatta tgtcaaggat aacattatgg cagctatgaa tgtcacaggt caaaccgaag
     4321 tcaagagtgg tgccctgatt ataaaaattg ctaaaaatcc agaatcagtc aaggtcaacg
     4381 aaaatgacct tccgaaaaaa tattttacaa aaaaagtgac gcttgcgccg gacaaaaaaa
     4441 cactcaaaga gttgcttaaa tctggcaaga aagtcaaagg agccgagctc attagaacgg
     4501 aaaagttggt gattaagtaa tggaattgat gaataaaaca cgagtaacag attcactagc
     4561 agttgtgatt ggactagaat cgattgaagt acttgttact gaaggttttc tatttgatgt
     4621 tgcgattcgt tttgtaaaag tagacgaaac aaatcttgat caaggaaatg aaaagccagt
     4681 attcactccg gaatacaagc tggtcacagt tgctaaatac aaggaaaaac ctatctttga
     4741 atcggaggaa gatattcgaa aatttgagaa gcaagcaaaa gaagttaaat cgctatttgc
     4801 ctttgcaaag gtaaataaac aaaattggtt taacactgcc ctttatccag gagtgctgac
     4861 tgagaaagtt ggtgtttgat gaaaatttta gctattgatc caagcagtaa taaaattgaa
     4921 accagcacaa caggagttgt cttgttggat aatgcaagat tagttgatag ctgggttgtc
     4981 tcttatggta tgagaggttt cgctgattgg tttcacgaaa tcggaacaaa tcttgaattc
     5041 gatgtagtta ttgttgaaga atttaaggcg agggataacg aaaagtcaaa agataatagc
     5101 gtggcagaaa ccatcgctta tatccagctt tgttatccag aggctattct tcaatttaat
     5161 gcaggttaca agtcggatat tccaaacgat cttttgaaaa tcttagacct ttggaaattt
     5221 gaaaaaagtc atcatcaaga tattagagca gcagcaagac ttggattatt ttgggcaatg
     5281 agaaatgata ttgaagaagt ggttcatgat atcggaaagg tggtgagtga gtatcacaat
     5341 aacgctaaga aagtggcaag ctgaagcgat taaaagaagt gaacatttat ctaatggaat
     5401 ctttttagag gctcttgggg gcagaggcaa aactatctgt gcacttgcta ttgcaaaaca
     5461 taaaaaagct aaaaaaatca tcatcacaaa caatcgacta gctattctga atggttggat
     5521 agatgcagtc aagtttatga attttgataa aggtgttgag attatcattc agacagatag
     5581 atatcttcaa aatcaagtca aaaaggggca taaattagat tgtgatgtgc tgatagtaga
     5641 cgaatggcag aatatgtctt ctgacaaaca agtggcctta tatcgcaaaa taaagcgaaa
     5701 atacacgata ggtctttcag cgacaccaat tcggaaaaaa ggacaaaatt tctatccgct
     5761 tgaaaaaacg gtatttggtt gggcaacccc aaataataaa tttgactggc aaaagactca
     5821 tggaaaaatg gtctatgatc catttagcta ttcaaaagag aagtgggaag attttcaaaa
     5881 ttatgaaagt tatatctcga gcttgcctaa tttcttccgc tgggaagaga ttgaaggaat
     5941 tgagaatgca gttgagaata acggttttga gattaagttt taccaaaaga gagtcgcctc
     6001 tggcaatcca gaaaaacttg cagaatttag aaaactaaat cttgtaacag tggacggcaa
     6061 aactgcaatg gccaagcaat cgtttggaag aaagaccttt gaacgctacc ttaatcaaac
     6121 aggcgtagca gtcgattttc caaaattaaa gccagtaaat gcggatacgc cattgatgtt
     6181 acaacttgac ggtttaatcg aacgagcacc acacgatatg ttgattgtca gtaaatctaa
     6241 gcagattgtc aacgtcatta gcgagcgcca tcctgaaatt ggaatctgga cgggcgatat
     6301 tcaagaagga ctttataaga aattcgtggt tgctactagt caagtgttag gtgtcggagt
     6361 agacggcttg caacacaaat accaaactat tgtcgtattg gatccagtag aagaaggttc
     6421 tggagaatat gatgattatc gacaattgct ctggcgcata acaggaagtc gtcagcagca
     6481 tgatgtaaat gtaattgaat tttattataa agaaagttaa aaaaaagagg aaaacaaaat
     6541 gaataaaaca actgaaatga tcgtatttcg tagccgtaaa actggagaat ttcttaattc
     6601 ttacaaggac agaagttctt tagcatttgc agctgacttt tgcagcttgg aatattgttt
     6661 gaagcttcct cgtaaaaaat acgaagacaa caaaaagact tacaaggctc ttgctgcagc
     6721 ttttgactgt gaaattgtcg cagttgaagc ggaatacaaa ttgacctatc cgaatggatc
     6781 agaagttgaa cctatcaagc gtgaccgttc atcaattgag gacatgatta aggatattat
     6841 tggaggggtt ctctaatggc atttacactt ccagcaaata aaccacaagt tcctaaagat
     6901 accccacgaa attttttcat ctacggtgaa accatgagcg gaaagtctta tcttgcaaat
     6961 gaattcccaa atccaatcgt tttgaacaca gacgggaatg cagaagctaa cactgttcca
     7021 agcattcagc tgatcaatga aaaagatgac aagggacgaa ttaccaattc agtaattaag
     7081 cagcttggag atatcttgct tgctctccag acacagaagc actcttatga aacagtcgtt
     7141 attgatgtaa ttgacgatgt tattgaaatg attaagattg cagtttgtga tgaattaacc
     7201 ccagttggta aacctcgctt gaaatccttg tcggaaattc catacggcaa aggatacgac
     7261 ttctttaacc aagctatcac agaattagtc attgacctca aagcattgcc aatgaatgtt
     7321 atttacatca gccgtcaggt atctgaatat gatgacaatg gcaatgccac caaagacaaa
     7381 ccaagcttga aagataagta tgtcaatctt atcaatggaa actctgattt gatgatccac
     7441 actgaaaaac tcggcaacaa ctacaaccgt gaggttgacc gcaagcgtaa gacctactat
     7501 gtgaaccatg ttgatgacaa ggctattttg aaaatcttag caactatccg tggggctgtt
     7561 gaacctgcaa aaaccgaaaa gacaaaagag gcgcctaaga aagaagttgc ctctgatgat
     7621 gaactatttt aagaaataaa ggagaataca catgagctta ctagatatcg caaaatcaat
     7681 caaaaaagag ggctttgacc cacgcaaaga cagcgccaac ggtcctgcac caatcccagc
     7741 tggtacttat ccagtagtcc tgaagaaagc aactttcaac gtatcggaca aaggctggga
     7801 aagccttggt tatcaatttg aaatccgtgg cggtgattac agtggacgct ctgaatttgc
     7861 aacatttggc acactgactg aatggaacgg taaggacctt aactgggcag ttgaacgcac
     7921 catgaaattc tttatcaaag ccttggtcct tgctggcgac agtatgcaag gaaatgaaga
     7981 agacggtaaa gccttggaag aggctctaaa acgtaaggca gttggctctt actacaacct
     8041 tgttatctct gtgactaagg ggaaagatgg ccgtgagttc cgaaactatg accttgaaga
     8101 agaagcacaa ccgctgactg aagctgatat tgatgacgat gacctccctt tttaagaaat
     8161 aacaagttct gggtcattga tgaaactgat gaaagattag gaccattcaa tacatttgaa
     8221 gaggcttatc aatcgttgtt attttattta aaaatgactg aagatgaata tcaatcaaat
     8281 tatatggccc aagaacttgt ttatatttac aaaaaggaga agtaatcatg tcgtcgatga
     8341 aagaatacgc attacagtac caaaagttag ggttctcagt cattccaatc aatcctaaaa
     8401 acaagatgcc tttgattgat tttgctgata agccagccat gactccatct gagattgaaa
     8461 acttttggga cggctaccct aatgcaaaca ttgccctaaa gattaccaac ttctttgtca
     8521 ttgatattga caaacacggc aaatcgaacg gttttgaatc gctaaaaaaa tggaaacatc
     8581 taaatttaat cgaaccgaca ctgcaagcta agacggctag tggcggtaaa catctattct
     8641 acttcaaacg agaagatgag ccgatcactc agatgattgg attcttgcct ggtgttgata
     8701 ttaaggctca cgaaaataat tatgtgttag tcgcaccctc tgccacagat aaagggcagt
     8761 atgagtggga tctggaaaag tctaaggaag gtggcacgat ggtcactcct tcaaaagatt
     8821 taatccagtc tataaaaaaa cagtatggcg aaactcacgg ttataagtat gatggtaagg
     8881 acggtcttag ggatttagtt agacgttcac atactagaga ccgaacacag actacagatc
     8941 tctttgaaac catcgccctt ggttttggtg atgaaggtgg acgaaatgac aaactagcaa
     9001 aattcgtagg tggtctctta tatcgtgcgg tcgacgatgg tgtagttgtt caacttgcaa
     9061 gattagcaaa tgcaaatagt ccaaaccctt tgcctgaaaa ggaaatgatg cgtactattg
     9121 aaagtatgat taaaaaagat aggaggtgat tgtgattggt aatgtagtaa gtattgactc
     9181 acaacctaag atgataacga ctgccaaggg agacatcaag gccaacagtc caagtaatgt
     9241 gttgatgtct ttcaaagctg atgatcagtt gagtatttac ctaaagcaca acgatttttc
     9301 ccaagagcat gaactcctta aagatatcaa gatcggcaac actcttttta aaaaaggtga
     9361 gctcccttct aactttgatt cagtcgtaaa agtttacttt gaaagtgtgt taggtgttgc
     9421 tttctcaaac caagcgatgc ttgatggcat ggagactttc ttttcagaaa gatcatacaa
     9481 tccagttatt gagtatatgg agagagcaac tgaaaagtgg gacggcagaa accggattga
     9541 ccgcatgctt caagtatatc tcggcgctga agatatccct ttagtttcta aaatcgctca
     9601 aatgtggcta gttggtgcag ttgctaaagt ttatgatcca tacgttaagt ttgactatgt
     9661 tctggacctg gtcggtggac aaggagttgg gaaaacgtcc ctccttcaaa aattgggtgg
     9721 cgaatggtat acggatgccg taacagattt ctttaataaa gataattacg acattatgtt
     9781 aaagagtcta atcgtcaacg atgatgaaat ggtggccagt aatcggatga gctttgcaga
     9841 aactaaggcc tttatttcta aaactagcct acgttatcgt aaaccataca tgaaacgaac
     9901 agaagaattt gccaagaact tcatcttagc caggactact aatcaaaaag aatacctcaa
     9961 ggacaaaacc ggtgaacgtc gatttctccc gattatggca gatagcaagc aacaaaagaa
    10021 acatccaatg gaaatcgatc ctgatacaat cgaacaaatt tggggcgaag ccgttacaat
    10081 ctatcgtgct ggtgctgatt tgatgtttga tgaaaataca gaggatgaac tgaatatcta
    10141 ccgtgaacag ttcatgtatc gtgatgaagt tgaattacaa gtgcttgaat atcttgatat
    10201 gcccgtccct gaaaattggc aaaactggtc tattcagcaa caacatcaat acacaagtaa
    10261 atatttcgat aatagtagcg actttgatcc tggaagcaaa aaactagata aggtctcaac
    10321 tcgtgaaatg atgtacaact tatttatgag aaattcgaat gacaggaagc tgtcaacgaa
    10381 gattaacatg atcatggata atcatcctga ttggaaaaaa agtgttttcc gggcaggagg
    10441 taaaaataca aaagggttcg taagagtgaa gaattcggaa aaaactaatc ggtagcaatt
    10501 aaaaaattat tggtagtcat cggtagcagt tgagggggag atcggtagca ttctaccgat
    10561 aaaataggac atcggtagca catcggtagc agtctaaccc cttgatatta ctgactttta
    10621 tttaatattt atatataatg ctactcttct acctatattt ttaaaaaaag tatataaaat
    10681 aatagtaata ataaagaaag cctatagaat agggattctt gaaaaaaact ttttactttt
    10741 tagaatttat cggtagcacg gtagcagttt agaaaaaaga ggtaaaaatg tcatacacag
    10801 taacattatt ttttgacaac atggtagacg aaactcactt ttttaagaaa gagagtgatg
    10861 ctgccaaatg caaggctcag ttagaaagca agtatcgagg gaatcgaatg tataaagtaa
    10921 agatggagga gatggagtaa tgagttatga tttggaaatc ttagcgaaaa tagagagtgg
    10981 agattatatt tgtattgctg aacctagata tagttctccg acctacaatc ttggaaaaat
    11041 gtttagggtg gctatggatt gggatttcga ccaaggcaca atttacaatg ttgctgatat
    11101 ttttgaaaat attaaacgtg gcataactga attggaaagg caacctgaaa aatatgtaca
    11161 atatgaacct gcaaataaat ggggaacgat caatgatgcg ttatatgttt tgagatcgtt
    11221 aagggactgt attttagaac aagatattga tacgaaatat ttatatgtga ggtggtaaat
    11281 tgaaacgacc aaacagatac ccgtacacta aaaatcaatg ggttgaagaa accgttgatc
    11341 actatactta taaaaacgat atttgctata caagtcacat tttagaaaat agacttactg
    11401 gagaaattaa ggacaaggag ttgaagtgat ggaagagtta aagcgaaaag ttaatacagt
    11461 atacaactgg acggtagaag acgggaagcc gcaacctccc aagcaagatt taccacaagt
    11521 ggtgaaagac cgggcggact atttttggga aatggcagaa gatggtatga cgtttatggg
    11581 agcgatggaa tgcatcttcg ctgatgaaaa gcctacagac tatgatttgg gagctactaa
    11641 ggattggttg ccaaaatcta aggagtttga tgattgggtt ggttattcgc caagcatggc
    11701 tcaggtagtt attgcagttt atttgattta tagaggaaac taagatgaat aagcaggaat
    11761 tgattaaaaa attagaggaa cgaagaacaa taactgggaa ttttcaaggt tatgtagttt
    11821 ggtggaagga tgtaaaagaa atctttgaac aactaggcga accgcaacca gtcaaagtac
    11881 cgcagtttgt ggcggattgg attagaaaat gtaaaatgtt taagcatttt gctgtaagtc
    11941 tatcttttgc attacaaccc attgtatggg aagaaaatgg gttatctcac gagtgcattg
    12001 aatggttgat ggatgcaaac aatcaagaac tcttcgcact agcttggctt aacggctacg
    12061 aggtcgaaaa agagaagcgg tattttgtta agattaaagg gaatattaaa gaaaatatgt
    12121 tggtttatgg agaacttttg aaaaggtatt tctttacaaa aagctttagt ttagacgatg
    12181 ttatatattc ccacacccgt aaagaactag aagacgcaaa cttcggctgg gtgtttgatt
    12241 gtgaaggaat tgatatagag gaggtggagt gatggaagat gaggaaatca taggcaacat
    12301 ctacgcaaac ccagagcttt tggaggtcaa cgagtgagat attttaaaat cctatgtatt
    12361 gttttattcg catccttact cgtagcatgt caccagattt cgagtgggac agtggtagat
    12421 aagtacattg atgaacctca cacaacgttc atacctgtta taaatggtaa aagttcggta
    12481 cttgtgccaa ccagaaccaa aagaaaatac attctggtcg tttcaggata tgcaggtaat
    12541 aagcaagttg aagaaaggtt tgaagtgaca gcaaatgaat acaagcacta tgaaattggc
    12601 aatactttta tacaggatgc cgttttagaa aataaggagg aggataaata atgagaccta
    12661 aaaaataccc acaagatact caatagctac taaaacaaaa aaagccaaga cactctctgt
    12721 ctcagcaata atctcaataa tattattata tcacaaagga gacagagagt gaacaaggct
    12781 aaagaactat tgaaagagtt gcagaatctg gacatggaca ttcaaagccg tatagatgaa
    12841 attaacgagc ttgaggcagg tttgctttca agccccaagt ggattgacgt caaagtccaa
    12901 ggtggtcaag ctagaaaagt tgatgatgtc tatactcagc ttgtcgtgat gaaagaggct
    12961 atagaacagg atactaaaga ggttatcaac agaaagcttg agcttggtag gttgattaac
    13021 aagctgaaaa atccaaagag caggtctatt ctcagggtga cttacattac taagatgtat
    13081 gttgatgata tttgtgacaa aatggaaatc agcagaacaa ctttctacac ttggcggaat
    13141 atggctatct ctgaactgaa tgaggttttg gagagaatgg aactaaattg aactttacaa
    13201 aaccgtacgg gaaaaaatga tacttgttag cacagttttg taattctgat aaaatggtag
    13261 tatcaagaat tgaaaagaga ggtctcagaa ttggtagatg gttacctgta atgtcagggg
    13321 gctgtaatgg ccttggaggt tcaagtcctc ccctctcctt tgagtgtttg tgtcccagaa
    13381 tgagttaaat cttctgggtg gggattcaca tatcactcat taacttctat cactcattaa
    13441 cttaaaaatg gttgcagtag cgactgaacc ttgcatgatt gcgtagctaa ttatattccg
    13501 gataagttat aagctagagg gtttgattcc ctcagaggtt gtaaagacta caaaaaataa
    13561 aaatgaagtc aaaatttaat acgcacgcaa ggtagtagtc gccttgcact tttagggctt
    13621 agcctagata atctgtggta actaaggaaa aggatgtttt taaatctatc aaacatcctg
    13681 ccagcaatgg tcaatctaag caatgtaatc ttaactattt cagttttgga ataggtaggc
    13741 gaagttaaag caggaagatt ccaacggcaa ggtgctgagg aaatgcaaat gtggcagttt
    13801 ggctgtgaga cgagtctata agaggaatga ggtattcggt ttgaggtgca acaagagctt
    13861 aataccatat cttacaaaaa ttgggcgcct cccaaaagta tgtaaggtga gtcgattgtc
    13921 cgcaaaacaa tcgataacaa gcaggcgctg tgcattttgt tcttcaaaag agaatgaaac
    13981 acatggcgat gcgtgtctgt gatagatgaa agatgatttt tatattttaa ggctattcaa
    14041 gatagaaaaa actcaaaaaa gcaaaagtca tcgcccgtcg taaacgaaag tgcacttcgg
    14101 caattagatt gcctgctcaa gtctcgcaag gatgagagta aagtcaaaga gtaaagcagc
    14161 ttagactttt agcggagtct tcgttaattg aaaaatggcc tagtagtttg cgatgtgagg
    14221 agtgattggt ctaaccaatc gtgcatgagt gatacaagta ggaatatttg tggacaagat
    14281 aataaactat aagttatcaa aagtcactcg tttaaagcag tagtctcatg ctagttaatg
    14341 gatacatggt agacggatta agtcctgttt agggaattga aacgtaggca ggttcgaatc
    14401 ctgtcgttcc aattgcgatt ttaattcgca gagagaggtc ttgaaaaggt cgcacatcgt
    14461 gtggcttttt ttgattgttt gaaaggtggt gatggaaaat tgaatgaaag acaaaggcgt
    14521 tttgcagatg agtacatcat ctcaggtaat gcttatcaat cagctttaag agcaggatat
    14581 agtgagaaat atgccaaagc aagatcttct gaattgttgg ataatgtcgg aatttctgat
    14641 tacatcaaaa atcgaatgga ggagttgcaa gatgaaaaaa tcttaactca aaaacaaata
    14701 cttgtgatgc tatcagaaat tgcgtcggga caagcgaaag aaacaatagt agtcacaaca
    14761 aaagtagctg agttgatgac tgatcccgtg actggtaagt ctgtaaaagt ctacaatgaa
    14821 atccctcaac ttgtcgaata cccaacaaag aacagcgata ggaataaagc tcttgaattg
    14881 ttaggtaaac gacataagat gtggacagac aaagtagagg cagacgtttc tggaacggtg
    14941 gtgtttgcaa atgagtcaga catatcagat taaacagaac gatattgttg ttgacctacc
    15001 taagacagta ggagctggat acggacagtt ctggcgctca agaagtcttt atcgtgtagt
    15061 caaagggtcc cgtggttcga agaagtccaa gacaaccgct ttgaattatg ttatccgtct
    15121 tttgaagtat ccctgggcca acttgcttgt tattcgtaga tactcgaata ccaacaagca
    15181 atcaacttat acggatttta aatgggcgtg taatgtgttg ggtgtgactc atttgtttaa
    15241 atttaacgag tctttgcctg aaataaccat aaaagcgact ggtcaaaaaa tcctattccg
    15301 tggtttggat gatgaactca aaatcacatc tatcacggtc gatgtcggca gtctttgttg
    15361 ggcatggttt gaggaagcat atcaaattga gactgaagac aagttcagta cagtagttga
    15421 gtcaatccgt ggtagcttag atgtacctga tttctttaaa caaatcacag tcacatttaa
    15481 cccgtggaat gagaggcact ggctcaaacg tgtgttcttt gatgaagaga ctagccgagc
    15541 tgatacattc gctactacaa ccacttacaa atgcaatgag tggcttgatg aagtcgatat
    15601 taagcgctat gaggacttgt atcacacaaa tccaaggcgt gcgagaatcg tttgtgatgg
    15661 tgaatgggga gttgctgagg gtttaatcta tgaaaacgtg actgtcaagg atttcaataa
    15721 agatgaatta ctacaagatt cagctaataa attatgtatc ggtcttgact ttggttttac
    15781 tcatgatcca actgctttgt gttgttcgtt gataaatgac acgacgaaag agatttatgt
    15841 ctttgatgag gcgtataaag ttgggttgat aac
//
LOCUS       DAVLIK010000041        15612 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLIK010000041 DAVLIK010000000
VERSION     DAVLIK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.041"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..615
                     /locus_tag="VXE87_001570"
     CDS             <1..615
                     /locus_tag="VXE87_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843096.1"
                     /translation="AETVSQTVSLPNAKIVLDRFHIVQHLSRAMSRVHVQIMNQFHRK
                     SHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLY
                     QLLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLE
                     ATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(714..2336)
                     /gene="groL"
                     /locus_tag="VXE87_001571"
     CDS             complement(714..2336)
                     /gene="groL"
                     /locus_tag="VXE87_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0843097.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2352..2636)
                     /gene="groES"
                     /locus_tag="VXE87_001572"
     CDS             complement(2352..2636)
                     /gene="groES"
                     /locus_tag="VXE87_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0843098.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2792..3187)
                     /locus_tag="VXE87_001573"
     CDS             complement(2792..3187)
                     /locus_tag="VXE87_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0843099.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3265..4026)
                     /locus_tag="VXE87_001574"
     CDS             complement(3265..4026)
                     /locus_tag="VXE87_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0843100.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(4068..4694)
                     /locus_tag="VXE87_001575"
     CDS             complement(4068..4694)
                     /locus_tag="VXE87_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0843101.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4710..5027)
                     /locus_tag="VXE87_001576"
     CDS             complement(4710..5027)
                     /locus_tag="VXE87_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0843102.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(5024..5323)
                     /locus_tag="VXE87_001577"
     CDS             complement(5024..5323)
                     /locus_tag="VXE87_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0843103.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5608..5799)
                     /locus_tag="VXE87_001578"
     CDS             complement(5608..5799)
                     /locus_tag="VXE87_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV0843104.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5960..6634)
                     /locus_tag="VXE87_001579"
     CDS             complement(5960..6634)
                     /locus_tag="VXE87_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843105.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(6640..7086)
                     /locus_tag="VXE87_001580"
     CDS             complement(6640..7086)
                     /locus_tag="VXE87_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0843106.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7200..7703)
                     /locus_tag="VXE87_001581"
     CDS             complement(7200..7703)
                     /locus_tag="VXE87_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0843107.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7700..8062)
                     /locus_tag="VXE87_001582"
     CDS             complement(7700..8062)
                     /locus_tag="VXE87_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV0843108.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8128..9993)
                     /locus_tag="VXE87_001583"
                     /pseudo
     CDS             complement(8128..9993)
                     /locus_tag="VXE87_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(10003..10473)
                     /locus_tag="VXE87_001584"
     CDS             complement(10003..10473)
                     /locus_tag="VXE87_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0843109.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(10597..11313)
                     /locus_tag="VXE87_001585"
     CDS             complement(10597..11313)
                     /locus_tag="VXE87_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0843110.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12194..13609)
                     /gene="ply"
                     /locus_tag="VXE87_001586"
     CDS             complement(12194..13609)
                     /gene="ply"
                     /locus_tag="VXE87_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0843111.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALMKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13620..13952)
                     /locus_tag="VXE87_001587"
     CDS             complement(13620..13952)
                     /locus_tag="VXE87_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843112.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(14023..14631)
                     /locus_tag="VXE87_001588"
     CDS             complement(14023..14631)
                     /locus_tag="VXE87_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843113.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14644..15102)
                     /locus_tag="VXE87_001589"
     CDS             complement(14644..15102)
                     /locus_tag="VXE87_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0843114.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15227..15612
                     /locus_tag="VXE87_001590"
                     /pseudo
     CDS             15227..15612
                     /locus_tag="VXE87_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4571 a         3614 c         2816 g         4611 t
ORIGIN      
        1 gctgaaacag tctcccagac tgtttcactc ccgaatgcta aaatcgttct tgatcgcttt
       61 cacattgtac aacatcttag ccgtgctatg agtcgtgtgc atgtccaaat catgaatcag
      121 tttcatcgaa aatcccatga atacaaggct atcaagcgct actggaaact cattcaacag
      181 gatagccgta aactgagtga taagcgattt tatcgtccta cttttcgtat gcacttaacc
      241 aataaagaga ttttaaacaa gcttttgagc tattcggaag acttgaaaca ccactatcag
      301 ctctatcagc tcttgctttt tcacttccag aacaaggaac cagagaaatt tttcggactt
      361 attgaggaca atcttaagca ggttcatcct ctttttcaga ctgtctttaa aaccttcctc
      421 aaagataaag aaaagattgt caacgccctt caactacact attctaatgc caaactggaa
      481 gcgaccaata atctcatcaa acttatcaag cgcaatgcct ttggttttcg gaactttgaa
      541 aacttcaaaa aacggatttt tatcgccctg aatatcaaaa aagaaaggac gaaatttgtc
      601 ctttctcgag cttagctgac ttcaacccac tacagttgac aaagagccta taaaaagaag
      661 ggttagtcat tccctccttt tgtgtttttt ataagttgtt ttctatagaa agcttacatc
      721 atcccgccca tcatacttgg atccattgct ggagctgggg ctactggttc tggtttattg
      781 gctacgactg cttctgttgt caaaatcaag ctggctacag atgctgcatt ttgtagggct
      841 gaacgactca ctttaactgg atcaatgata ccttgatcaa tcatgttaac ccactcgcca
      901 gttgctgcgt taaatcctat accaagctca gcatttttca aacgatcgat aacgatagat
      961 ccttcaaatc ctgcattgtg agcaatttga cgaacgggtt cttccaaagc acggagaaca
     1021 atattacgtc ctgttgcttc atctcctgtc aattccaagg tagcaacagc tggaatcaca
     1081 ttggcaagag ctgttccacc gcctgcaaca ataccttctt caacagctgc acgagtagcg
     1141 ttgagggcat cttcaatgcg gagtttcatt tctttcaact cagtttcagt tgcggctccg
     1201 accttaataa ccgctacacc acctgacaat ttggccaagc gttcttgcaa tttttcacgg
     1261 tcaaattcag aagttgtagt ttcgatttga gacttgataa ccgcaacacg gtgagaaatc
     1321 gcttcaggat ttcctgcacc ttctacaata accgtgctat ctttgtccac ggtcactctc
     1381 gctgcttgac caagagcttc aattgtcgca tctttcaact caagaccaag gtcttctgtg
     1441 ataactgttc cgcctgttaa gatggcgata tcttcaagca tggctttgcg acggtcacca
     1501 aaaccaggtg ccttgactgc tactacgttg aaggttccac gaatcttgtt caaaacaaga
     1561 gttggaagag cctcgccatc cacatcatcc gcaataatca agagtggacg attgctttgg
     1621 agaatgcttt ccaaaagtgg caagatctct tggatattgg aaattttctt gtctgtaatc
     1681 aaaatgtacg gattttcaag gtcagccacc attttttcgc tatctgtcac catgtactgt
     1741 gaaaggtaac cacggtcaaa ctgcattcct tctacgactt caagctctgt ttccatacca
     1801 cgtgactctt cgatggtgat gacaccgtct ttgccaactt tttccattgc ttcagagatg
     1861 tactcaccaa ctttttcaga acgagaagat acggctgcaa cttgagcgat agcttcttta
     1921 ttggcaacag ggatggcgtt gtttttcaaa gcttcaactg ctgcggcaac tgctgtttca
     1981 atcccacgac gaataccgat tggatttgca cctgctgtga cgtttttgat tccttcacgg
     2041 acgatagctt gggtcaagac tgttgcagtc gtagtcccgt cacctgcgat atcattggtt
     2101 ttagaagcta cttctgatac caatttggca cccatatttt caaaatggtc ttctaattca
     2161 atttctttgg caatagtcac accgtcattg gtaatcaatg gtgagccaaa tgatttttca
     2221 agaacgacat tgcgaccttt tggtcccaag gttactttaa cagtatctgc aaggatatcg
     2281 acaccacgga ccatagctga acgggcatct gatgaaaatt taatttcttt tgacatactt
     2341 actttctcct tctattcttc aatgattgcc aagatgttag cttcgcctac gatgatatac
     2401 ttttcatcgc catctttgac atcaagacct gcgtgggctt caactaagac acggtctcca
     2461 gttttaacac ttggagcaac caagtcaccg ttcaaggtac gaacaccttg tccagtagcc
     2521 acaacttggg ctgttttggt tttttcttgg gctgaacctg cgagaacaaa gcctccaaca
     2581 gtttgttctt tttcttctac ttttaagacc aaacggtccc ctaatggttt caacatctga
     2641 tttcctccat aatgagatag atattattag cactctttat acctgagtgc taattcatag
     2701 ttctattgta tcacttagtc agaaataatc aagaaaaaag tctgactttc tcaagataaa
     2761 aagcctgaga ccaactcaga ctttttaatt cttaaaatgg caattcttcc tcttccaaga
     2821 ccaaatctgc caaatcttgg cctgcattat tttcacgcat agcacgttgg gcacgacttt
     2881 ccaagagttg gaatcctgtc acaaggactt cggttacata attcatctga ccatttttct
     2941 caaagcgacg ggtacgcaat tctccatcaa cggaaatgag actacctttg gttgcgtagc
     3001 ttgccaaagt ttctgctagt ctgccccata ggaccatatt gacaaaatca acttcacgtt
     3061 caccgttttg gtctttgtaa cgacggttga cagcgatagt tgctcgcgct actgacttgt
     3121 cattgttggt tttgtgcaat tctggtgtag acgttaaacg tccaatcaag ataactttat
     3181 tatacatatt ttcttcctcc tacttatcta ttcgtaggaa atcaaaaaaa gttacagaaa
     3241 tttgtaactt ttcgagaaaa ttttttattt tttatgaacc atgaaacctg tcgcctgttg
     3301 attggccata atggtcatat ctgtaatctg aacacgacga ggttgactag tcacatagac
     3361 tactgtatct gcaatatcct gagcttgcaa agcttctatt ccttggtaaa cggacgcagc
     3421 tcgttcttta tcaccatgaa aacgcactgt agaaaaatct gtttcgacaa ttccaggctg
     3481 aatggttgtc accttgatat ccgttgcgat ggtatcaatt cgcagtccat ccgaaaaggt
     3541 cttaaccgca gccttggtag ctgagtaaac agcggcacca gcataggcgt agattcctgc
     3601 ggttgacccc atattgataa tatgaccttg attgactttt atcattgctg gcaagaaaca
     3661 gcgagtaacc gccatcagac ctttaacatt ggtatccaac atggtcaaca tatccaactc
     3721 ctcatagtct tgatagggag ccaagtcaag agccagtccg gcgttgttga ccaagatatc
     3781 aatcctccct atcgtttcta gaatatcaga gcaaacagtc ttcaccatga ccatatccgt
     3841 cacatctagt ggaaaagtcc agacggtttg atttggaaag cttactgcaa actccgactt
     3901 gaggatttct aatctgtcta tccgtcgtcc tgttagaacg acatcctcac cctgctccag
     3961 ataagcacgc gcaatcgctt caccgattcc tgaggttgct cccgtaatca caacattttt
     4021 tgccatctta tttccttcta gctggtctat cagatattaa caacttctta ggcagtccag
     4081 tgtttagctg agtcaaatgg tgttccgaca acttggtctt ctgataattc aagcacccca
     4141 cgtttttgtg gagcatttgg cagatgcaat tcacgaggac tgcacatcat accaaaactc
     4201 ttttcaccac gaagttcacc tgggaaaatg agattccctt ttggcatcat agctccagga
     4261 agcgcgacaa tggttttcaa ccccacacgc gcattgggag ctcctgcaac gatttgtaca
     4321 gtcttatcac ttgcgactgc aacttggcag atgttgaggt ggtcactatc tggatgggct
     4381 accatctcaa caatttcacc gacaacaaac ttaggttcct tatcattaac aatttcttct
     4441 gtaaaacctt ccgcctgcaa ctcttggttc aaacgagcga cttgctcatc tgtcaaaaag
     4501 acttgaccgc gctctgcagt ttcaaataaa cttgaaactt cgaaaatatt ccaagccact
     4561 gtttccccat tatctttgag aaaaacacgg gctaccttgc ctttgcgctc cacatccagt
     4621 ttggcatctc cgctattttt cacgatgacc ataaggacat caccgacatg ttctttatta
     4681 tatgtaaaaa tcattgtttc ctttttctcc tatttcagtc ctgctaaaaa gtcattgatt
     4741 tgttgcttgc ttttacggtc gcgattgaca aaacgaccga tttccttgtc cttttctaga
     4801 acaacaaggc taggaattcc gtaaacatcc cagagtttgg ccaaatccat atactgatct
     4861 cggtccattc gaataaaggt gaactctgga ttggtctcct caatctctgg taaggcagga
     4921 taaatataac ggcaatcgcc acaccagtct gccacaaaaa ggaagacctt cttgcccgct
     4981 ttttccacta aagatgctaa ttcttctaaa cttgctggct gtatcataag acttcctcct
     5041 catagactag gtcttcattt tcatagacaa aggtataatg acggccatcc tcaaaaatga
     5101 cgccaccaac caagctctcc agactgcttt cgtaaacttg aacatagagg gtcgcaattt
     5161 cccccatgtc ggaaaaatgg tctcgcacaa tctctgtcaa ctcttcctga gtcttcatga
     5221 gcttacggtc atctgcaact tttttcgtag caagagcaag gcttccaata cctagcagag
     5281 ccaagcctgc catccacatt tttttagctt tcataccatt cattttaaca caaaaaaggc
     5341 ttcaggacaa atgaggaagc agcagaaaag caagtaaaaa gcctcttcct ttaaggaaaa
     5401 ggacttcgta tactaagagc aaactaggaa gctagccgca ggctgctcaa aacacggttt
     5461 tgaggttgta gataaggcga cgctgacgtg gtttgaagag attttcaaag agtattattc
     5521 ttattgccag gcacctaagt tgccaacgta gtaaccatca ggtgtgtagg tattgcgaaa
     5581 catcttactt gatgaagcca gataatacta cttgccattg tctttgaccc aatcattcgc
     5641 aatcatggaa ccagaagaac ttacataata ccattctccc ttgtcataaa cccaagtact
     5701 gactttcatg gttcctgagc aattaaaggc aaaaaaactg tccaatatca ttcgtttttt
     5761 aaaagcattt gacactacat catctacgct gtagtacata gatacatcaa acgtaaaagc
     5821 caaaatatcg aaaaatatac aacttttaaa ggcagcattt cattttttaa agtctaacaa
     5881 ccatagaact gaaatcagag caaggcatca atttcctact cttagtacgt ctattttgat
     5941 ggttgaagtg aagatttttt tatttaacgt agacaagctc caacttccca aaggccacgt
     6001 ctccacgaat aatcaaggtt ttgcttgttg gcgctacagg agcgtccgcc ttggctgcac
     6061 caaaggatgt ttctactttc aaatcgacac gccagtgttg tggaacatag acggttgcat
     6121 ttccgaaggc cacttcaata tttaaagttg caaaatcacc tagcatctct gcattatcat
     6181 agtagatttt agcatcccca aaagcgactt ccacttggtc atctacgaga tcttgatctt
     6241 gcttatagaa ggtcccgcta ccaaaagcga cttccttatc cgtgacgact gtttttttcc
     6301 cattgtacca ccattttttt tcattccaga acttacttga atgcgtcaga taaccaacac
     6361 caagtaccac caagatgcta gcccaaataa gagaatgatt ggtaactggt aacaagtcat
     6421 aagcgtaatt tgcaatgatg agcgccagta aacctgtaaa aactgccgaa gtgagatgac
     6481 gtctaaggat ggactcaatg gacttataag caaaaaaaac aatacctagt aaaggccata
     6541 ttttaccatc caaagaagga attccaaaat tcccttgcag caagatccaa gctgctaaaa
     6601 ccaataaaac aataccaaat gctttctttt tcatgttttt tacctcatgt ttcttagatt
     6661 ttcttttagg agggattggt aatgccgtga gacatgaacc tccttgtgcg tctgataaaa
     6721 ggaaatggtg cccgttcctg aaaaggactt gtccactgag taaatctgac ggatgtttgc
     6781 gatcgttgac ttggaaactc gattaaaata gcgaggcaag atagactcca actcatagag
     6841 cttgaggcga acctcataag cttccttctg gttatgagcg tagatcttgc tcccttctgt
     6901 ttcaaagaag agaatttctg acaggtctag ataatattca cctgtcccct tgtaaaaagt
     6961 caacctcgga gcctttgact cttgcaagag ccgttgcaag tctgcaattt catctgtcaa
     7021 agtgggggtc ttgatgacaa tttcagtctc ctctaaattg ccgtcaatct caattcgtaa
     7081 cttcatcaca tctcctttct gactctacta tatcaaagct aaattaggaa tacaagggca
     7141 aaaaagcaag tggtcaattt gaagcagtaa gtggttgtag gactagctta acttacatgt
     7201 cagaatagga agaaaaggaa tccccacacc aaaccacaag catagccaac caagacatcc
     7261 ttgggataat gaacaccccc taaaaccctc accaacccca gcaaagctga aaagatcaag
     7321 catactaagc caataggtag actagcatgc agacaggcca tggagatgat agttgccgaa
     7381 aagacatggc gactgggcat cgaccgtccc gaactatcct tatcaagaag gggacagata
     7441 tcccaagttt cataaggtct cgggtgattg attttcttac gaaacaggga caaggccaca
     7501 aaacctgatg caggaataag cacataaacc ccaacttgct gaccaagtcc tagttgcagg
     7561 taagtggtga ctagcaagat cagatagacc aggggcatgg cgactgtcat caaacgattg
     7621 aaactgcgta ataggaataa aagaattgga cgactagtta gtctggagct gatatttcga
     7681 taccattctt gataattttt catttatgct tctcatactt ttctagaact tgttgagatg
     7741 ttttcccctt ggcaagccaa tccactagct tgtccaagcg acgtatttcc tgcatcagag
     7801 gatcatcaat ttcctcaata cggacaccgc aaatcttccc tgtaattgca attcgttcag
     7861 ggacataata tggtgcttgt ctaaaaaaat ctccgtaagt aacatcccta tccagacaag
     7921 caagaacatc actcacttca taccctgtca accaactggt cacttggtga actgactctg
     7981 cctttccacc ctttcgctca acttttgcaa tcaaggctaa gtagacagca gcaaatttca
     8041 tattgtataa tttctgactc atacttctct ctttctatgt gtactagtat aaataagaaa
     8101 aagaaggccg tcaagccttc ttttgattta ttcttctgct tcatcttctg taaattgact
     8161 attgtacaag tcagcgtaga agccaccttg cgccatcagt tcctcatagt tgccttgctc
     8221 gatgatattt ccatctttca tgaccaagat caagtctgca tttcggatgg ttgacaagcg
     8281 gtgggcaatg acaaaggatg tgcgtccttc catcaaacgg tccatggctt tttggatcaa
     8341 ttcctctgtc cgtgtgtcaa cagaagaagt cgcctcatcc aaaatcaaaa gcggtgcatc
     8401 cttaagaagg gcacgagcaa tagtcaatag ttgtttttgt cctacagaca aggtcacggt
     8461 gtcatccaag atggtatcat agccatctgg caaggtcata ataaagtggt gaattcccac
     8521 agccttacta gcttccatca ttcgttcatc actaatccct atttgattat agatgagatt
     8581 gtctcgaata gttccttcaa agagccaggt atcctgcaag accattgaaa aggcatcatg
     8641 cacttctgaa cgcgtcatag ccttggtatc cacaccatca atgtgaatac ttcccttatc
     8701 aatctcatag aatttcatca aaagattgac aatggttgtc ttaccagtcc cagtcggccc
     8761 aacaatggca accttttgac cagcatgagc tgtcgcagag aagtcatagt cttgaacatt
     8821 gacaccgtcc accagaattt ctcctgctga cacgtcgtag aaacgtggaa tcagattgac
     8881 cagagttgat ttaccagaac ctgttgaccc aataaaggcc actgtttgac cagtttctgc
     8941 tttaaagcta acatgttcaa taactgcctc cgaatttgcc gcatagcgga aggtcacatc
     9001 cttaaactcg acctgacctt tgaagttttc atcagtcagc tgtacttgaa cagggttttg
     9061 gatagaagaa tgcaaatcta aaacttgatt aatccgctta gcagagacca tagttcgggg
     9121 aagaacgatg aagagtgctc ccatgagaag gaagcccatg acaacctaca tggcataaga
     9181 catgaaaata atcatgtcac taaagagagg cagacgcgct atcggagcag cgtcgttaat
     9241 cacataggcc ccaatccagt aaatcgctac actcaaacca cttgaaatcc ccatcatgat
     9301 aggattcaaa atagccataa gacggttgac aaacaaattc aaacgggtca attcatcatt
     9361 tactgctgca aatttttcat tttgataatc ctctgcattg taggcacgaa cgacacgaat
     9421 acctgttaaa ctctcacgag tgatactgtt cagtttatct gtcaacccct gaatcaagga
     9481 ctgttttgga aaggctagcg tcatcaaaac ggtcgtcatc aggacgttga caatcactac
     9541 cacaagtacg gcccagagcc agtattctga atgacctaaa atcttcccaa tagcccagat
     9601 agccataatt gaaccacgcg ttaccacttg caagcccata gtaatcaaca tttgaacttg
     9661 agtaatgtca ttggtagtac gcgtcaagag gctaggaatt gaaaatttct taatctctgt
     9721 ctgcgagtaa tccaaaactc ggttaaaaat atcacttctc agcctactag tataagaagc
     9781 cgccactcgg gatgcaaaaa atccaactgc aactacggac aagaaggcaa gaaaggacat
     9841 tcccatcatc atgcttgccg gctgccacaa ctcatctaaa ttagtttctt gactacctag
     9901 caaatccgta attttcgaga tataggtcgg cacttccaac tctagataga ccgaaaagca
     9961 agtaaagaga atggctagta aaatcatccc cattcttttc tactaattct tttggctaat
    10021 ttctttattc tctcctccta ttcccttgat atttgcctgt agttgaccga gaactttctc
    10081 aaaaatcagt aattcatctt catcaatgtc ttccatcaac tgcttgtcta tgcgttcaaa
    10141 aaaagcctta acctgttgca tctgagaacg tgctttgtcc gtcagacgaa caaacttagc
    10201 ccgcttatca acaggactcg cctccaattc caccaaacca ttttgcacta tacgcttaac
    10261 cagattacta gcaacagact tggtaatatt gagttcctgc tcgatatctt taatcaagac
    10321 caagtcttgg tttttctcgc gattatccaa aaaacgcaca acctgacctt gcggcccacc
    10381 cataaattca atgccgcaac gtttggcttc cttttgcacc atcaggtgaa tttgatgacc
    10441 aaaacgctta aagactaaca tcggtttacc cataatctcc cccttctaaa taaaaatagt
    10501 tctctggaga ataattaaat ttctatgaga actattttct tgattaaaaa aatcccaagt
    10561 gattttctca cttaggatca tgttctatag gttaaattaa aacccatcta cgttcgtata
    10621 aatcttttgg acgtcttcgt cgtcttcaag aacgctgtaa agtttttcaa aggtttcaag
    10681 gtcttcgcct gacaattcca cttctgactg aggaatcatt tccaattcag tcacttggaa
    10741 ttcttcaata ccagactcac ggagggcaac gatagccttg tgaaggtcag ttggcgctgt
    10801 gtaaactgtg attgtacctt cttgtgcttc tacgtcatcc acatccacat ccgcttcgag
    10861 caattgctca aagactgcgt ccgcatcttc acctccaaat acaataacac ctttgttgtc
    10921 aaagaggtaa gaaacagaac ctgaagcgcc catgtttccg ccgtttttac caaaggctgc
    10981 acggacattg gctgctgtac ggttgacgtt agaagtcaaa gtatccacaa ttagcataga
    11041 gccatttggc ccaaaacctt cgtaacgtcc ttctgtaaag gtttcgtctg tgtttccttt
    11101 ggctttatca atcgctttat cgataatgtg ttttggcact tgggcttgtt tagcacggtc
    11161 gataacgaat ttcaaagctg agtttgattc tggatctgga tcaccttttt tagctgctac
    11221 atagatttct acaccaaatt ttgcatatac tttagagtta gctccatctt tagccgtttt
    11281 cttggctacg atattggccc atttacgtcc cattaggaat ctcctttttt cacattttaa
    11341 tctttcttat tataacacaa gtttttttga ttttcactag aggaaatgga ttttattagc
    11401 aaatcaagct aggatagcac tttacctgct aagacggtct tgcctttcta tctttatcaa
    11461 cagacactca tccacattca aaaaacaaac tagaccatta tctgcaaata gaaagtttca
    11521 gccaagtttg acaaagtcag ctcaaattac tgtttgaagt ttgtagatat aagcgacaaa
    11581 aacaatcata ctgcaccttt tgttgacagt ctactccaga catatcatag ttcaagtaaa
    11641 tactttgaaa tccaacagtt cttataggcg ctattgtatt ctaagaaatc aatagaagag
    11701 tttctaagca aacctctaat actcaataaa aatcaaagaa caaaccagaa agctagccgc
    11761 aggttgctca aaacactgtt ttgaggttgc ggatagggct gacctggttt gaagagattt
    11821 tcgaagagta taatttacgt gttcccaaga tggagaagtt agactagtac actggcactt
    11881 ctaaaccatt gctagcaatt gatttgttca tatttaattt cattttttcc ataaatgggt
    11941 attagatata aacagcaaaa tatttccgat acgtgtcatt cttgaatttc caatcatcta
    12001 aaacaagtaa aggataatca atcccctgta tatcaaggaa ttggctaccc tttttacttt
    12061 tttacacatc ctgtttgata gactcatttt aacatcacga gcatactcca atggaaatcg
    12121 ctaggcaaga gataaacttt cagatatccg cagagagatc atcgcctctt tttgtcgcaa
    12181 gcattctctt ctcctagtca ttttctacct tatcttctac ctgaggatag agagttgttc
    12241 cccaaataga aatcgtccgc ttacgcacta gtggcaaatc ggttttttca taaaccgtac
    12301 gccaccattc ccaggcaagc ccggtacact ctctaatttt gacagagaga ttacgaacat
    12361 tcccttttaa aggaatacta gtggtaaagt gagccgtcaa atcctgccca tttctgtccc
    12421 aagccttagg agtcaagact tccttacctt gatgatcata ggataattca tcccaagtaa
    12481 tataatattg ggcaacatag gcaccactat gatccagcag taaatctccg tttctgtaag
    12541 ctgtaacctt agtctcaaca tagtctgtac tgttttgaaa ggtcgcaact acattgtcac
    12601 gtaaaaaaga agttgtatag gaaatcggca agcctggatg atctgctgta aagcgactgc
    12661 cttcttgaat caagtcctct accatatcca ccttgcctgt tacaactcgg gcacccgaac
    12721 ttgggtcgcc ccctaaaata accgccttca cttctgtatt gtccaaaatc tgcttccact
    12781 ctgtctgagg agctaccttg actcctttca tcaaagcttc aaaagcagcc tctacttcat
    12841 cactcttact cgtggtttcc aacttgagat agacttggcg cccataagca acactcgaaa
    12901 tatagaccaa aggacgctct gcagaaattc ctctctgttt taaatcctct accgttacag
    12961 tatcttgaaa cacatctcct ggatttttaa cagcgtctac gctgactgta taataaatct
    13021 gcttaaaatt aacaatctga atctgctttt cacctgaatg gacagagtta aaatcaatat
    13081 caagagaatt ccctgtcttt tcaaagtcag aaccaaactt gaccttgagt tgttccatgc
    13141 tgtgagccgt tattttttca tactgcattc tagctgggac attattgacc tgaccataat
    13201 cttgatgcca cttagccaac aaatcgttta ccgctccgcg aacacttgaa ttgctggggt
    13261 cttccacttg gagaaagcta tcgctacttg ccaaaccagg caaatcaata ctataagtca
    13321 tcggagcacg atcaaccgca agaagagtgg gattattctc taacaaggtc tcatccacta
    13381 cgagaagtgc tccaggatag aggcgactgt cgttggtagc tgttacagaa atatcacttg
    13441 tatttgtcga caagctccgc ttctttcttt cgataacaac aaactcatcg ggtagctgat
    13501 taccctcttt gatgaaacga ttttcaatac tttctccctg atgggtcaag agtttctttt
    13561 tatcgtaatt catagctagt ataaagtcat ttactgcttt atttgccatc ttctacctcc
    13621 taataagttc ctggattgag ttgcataaac tcagacttgt tcagcgaaat cagccgtggt
    13681 tggactaagt gatccaaaat ttcctcgtac aattcttctg agacattgcg tcgccgtctg
    13741 gctagataag aagtcggaat aaccgtatta tccaacataa ataccttatc taagtcaatc
    13801 aaggttggtc ttgtaaaagg attacgagct agatccggct cttctatcat aaagttcttg
    13861 accaaacgtc tggtcaagag agctggtttg aaggtctgat ttttaaccaa ctctttgttt
    13921 ttagtcatgc tgttgtcaat acagatatac atatgattct tcacagccaa atcgctacta
    13981 atagtcggaa aaggcaaata aagagctaca acatctcctc tcttaatcaa gcaagagcac
    14041 ccccttttct cctaatgtaa catagacagg attgaccaag tcttctgatt gactcagaat
    14101 ttccaaagtt tgagtttggc gcgctgtcaa tttagtagca tcttgtctct tcaatacaaa
    14161 atgcttgtcg ccaataacct tgacaatata atccttctcc aaagctgact ggtaaatcca
    14221 catcagatgt tgtctgtcct gagaactcaa gagagaagga ttttcaagcc tcccgatagt
    14281 ctgataaaaa tcaaaaacag gagctaactc ctgccaatct gattggctag ttgtcaaggc
    14341 tagaaaaagg gctttgcgag ctgatacttc ttggttagcc ttgagagtta ctttcccctc
    14401 caagtttttt agaaatcggg aaactccaga aagcaaattt ttctctaact gcgagaaata
    14461 aaaacctttc gttcccagac ataagtcttt catgtcgctt tctctagcaa ataagagctc
    14521 aaacatttga tagtaaaaga aaaatatctg gcactgggtc gcgctcatct tttccttatc
    14581 ggcttctttt tttaaccaga gcaagggcga caggtaactg gattgagaca tttcctctac
    14641 ctcctactct tttttaactg gagcatctgc actagctgcc acttcttttg actggatact
    14701 ttcccactgg ttaatctcct ctgagataag accttcgcat gtcttgacaa atagggcaaa
    14761 agccttggtc tttcctgcat atttctccgt ttggcattga tagaggaatt tttctttctc
    14821 caggagttgc gcagtttttt ggtaagaaat ccaattttcc tttgcattat acaaattgat
    14881 aatcccctca cacagcaagc cgagactgga taaggcaacc gaaatcaaac ggtagcgatc
    14941 acctggcata ggaatagcac aaaagacagc tatgaggaaa cctgccacga tttctgttat
    15001 ttttaatacc ttatagcgcc tacgatgttg aacgcttttc tttaaaaaat gagctatctg
    15061 tacgtctaat cgctctgtca ggtacatttc ttctggcgtc atattcgtaa ctcctttcat
    15121 ttactttgat aaccatagta taacatattt gaatatcaaa gtatagtaaa aactggacta
    15181 taacttatta gacttcctgc gaaacaaaat atggtatagt agttctatga attatgaagc
    15241 aagtaaacaa ctaactgatg cacgatttaa gcgtcttgtt agtgttcagc gtaccacttt
    15301 taaagagatg ttagctgtat taaaaacagc ttatcaaaaa agtcggacaa gctggtaaaa
    15361 tcttggctga cagtggttat caagggctca tgaagatata tcctcaagca caaattccac
    15421 gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaac catgcgctat
    15481 ctaaggagag aagcaaggtt gagaacatct ttgtcaaagt aaaaacgttt aaaatgtttt
    15541 caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg attgctggta
    15601 ttatcaatca ta
//
LOCUS       DAVLIK010000042        15309 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLIK010000042 DAVLIK010000000
VERSION     DAVLIK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15309
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.042"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            159..458
                     /locus_tag="VXE87_001591"
     CDS             159..458
                     /locus_tag="VXE87_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0843115.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            529..2550
                     /locus_tag="VXE87_001592"
     CDS             529..2550
                     /locus_tag="VXE87_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0843116.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            2552..3193
                     /locus_tag="VXE87_001593"
     CDS             2552..3193
                     /locus_tag="VXE87_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843117.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLSLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3297..4649
                     /locus_tag="VXE87_001594"
     CDS             3297..4649
                     /locus_tag="VXE87_001594"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0843118.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVAFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4653..5711
                     /locus_tag="VXE87_001595"
     CDS             4653..5711
                     /locus_tag="VXE87_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0843119.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGNKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5721..6887
                     /gene="divIB"
                     /locus_tag="VXE87_001596"
     CDS             5721..6887
                     /gene="divIB"
                     /locus_tag="VXE87_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0843120.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESN"
     gene            7153..7854
                     /gene="pyrF"
                     /locus_tag="VXE87_001597"
     CDS             7153..7854
                     /gene="pyrF"
                     /locus_tag="VXE87_001597"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0843121.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPIIQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            7888..8520
                     /locus_tag="VXE87_001598"
     CDS             7888..8520
                     /locus_tag="VXE87_001598"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0843122.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMNLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            9199..9963
                     /locus_tag="VXE87_001599"
     CDS             9199..9963
                     /locus_tag="VXE87_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843123.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVATLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVTYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9963..10715
                     /locus_tag="VXE87_001600"
     CDS             9963..10715
                     /locus_tag="VXE87_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843124.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLGEFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            10725..11423
                     /locus_tag="VXE87_001601"
     CDS             10725..11423
                     /locus_tag="VXE87_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843125.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11420..12067
                     /locus_tag="VXE87_001602"
     CDS             11420..12067
                     /locus_tag="VXE87_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843126.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRELSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12147..13012)
                     /locus_tag="VXE87_001603"
                     /pseudo
     CDS             complement(12147..13012)
                     /locus_tag="VXE87_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(13024..13781)
                     /locus_tag="VXE87_001604"
                     /pseudo
     CDS             complement(13024..13781)
                     /locus_tag="VXE87_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(13782..14069)
                     /locus_tag="VXE87_001605"
     CDS             complement(13782..14069)
                     /locus_tag="VXE87_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0843127.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            complement(14079..14459)
                     /locus_tag="VXE87_001606"
     CDS             complement(14079..14459)
                     /locus_tag="VXE87_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0843128.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESE"
     gene            complement(14419..15099)
                     /locus_tag="VXE87_001607"
     CDS             complement(14419..15099)
                     /locus_tag="VXE87_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0843129.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
BASE COUNT         4607 a         2649 c         3308 g         4745 t
ORIGIN      
        1 tgtagtaaaa tatctaaaaa attcgatttt ttccttgaca acaaataata aaaatgatat
       61 ttttatcaca taagaaagcg gtttcaacaa aagagagagg agggtttatt ttgttgcatt
      121 gttgctcaag gtgtgctttt tttgaaagaa aaaataaaat gaaaacgaaa aaacatagat
      181 tacttgctct agctcttatt tcaagtttta cattattggg agctgcatca gctgctgtac
      241 aatatccaga tggaggagta tggacgtatg gagaaggttc aggaggtggt tgggcttttt
      301 caaattacta tcatggtaaa aaatatcatt attcttctct tgtaagtaga tggaatagtc
      361 attcagataa aggagaagct tctgctggaa aaacctccta tgcatggatt tggactaaat
      421 ggggagaaca agtagcattt tactgtgatt atgactaatc gttcattgat ttaaatcgtt
      481 ccccttgtaa gaaattacag ggggaatttt gtttacaagg agtctactat gaagaaacta
      541 ttcatattat tatcaacttt ttttctcagc ttcttccttg cttggattat tgtcttacgt
      601 gcgccacaat atttatatgc aagctatgat tccgtttctt tacttcgtgt caaaaaagat
      661 actcaggaac cgacgcgtga ggtatttgaa caggaattgg agaattttgc aaactcagaa
      721 cagagtttaa tagctagaag aattgtagag ccgagtaagg atgggacgac tcactttact
      781 tatgcaactt atggtcaggg aactttacca aaagaattcc aagaagctag ccaagaaagt
      841 cgtgaacgta gtgatccgct aaatagttat ctccttttgt caggctcctt gacgaaagaa
      901 aagcttgccg ataaattagg agatttgggt tataaagcaa gtgctgaccg aaagataccg
      961 ccctattttc ttgcttttcg aatattacta aatcccctta ttttaattag tttagcaata
     1021 tttggcttat ctttctttgc tttagtgatt atcactcgga ttaaggaaat gagagcagca
     1081 ggtataaaac tcttttctgg tcagactctc ttatccatca tggggcattc tttatctact
     1141 gatatcaaat ggctccttct atcagccctc ctttccttcc taggtggggg agtcgttctt
     1201 tttagtcaag gtttgtttta tcctatcttg ttagccacct atggttttgg gattagtttc
     1261 tatctgttgt ttttattggc gatttcaatt ttactaatgc ttctttatct aatgagtttg
     1321 agttacaaag cattagttcc cgttattaag gggagattac cccttaaacg cctgatgatt
     1381 ttaaccctat tgtgtcagtt ggttgctgtc tttacagtag gctacgctgt taagacaggt
     1441 ttgatgtctt accaacgatt gaaagaactt gaaatttcaa aacaagcatg gcaggataga
     1501 gcagactatt atcaaatttc ttttggctta ggtgatagag gaaaagatac agaaaatcag
     1561 agcaagtggt atgcctttgc caaggaagca atcgaagaag aacaagctct ttatgtaaag
     1621 gataatctgc tccattttgc caatccacaa ggaaaaaatg aacagggaga gacactggat
     1681 acctatagtc cagatgctaa tacgctctat gttagtccca gttatttgga caaggaaaag
     1741 gtcgtggtag atgctgagac caaacagaag ttagcccatc tccaaaaagg tgagtttatc
     1801 ctcttgctcc cagaacattt gcgctctcga gaagcagaac ttaagaaagt ttttgaagaa
     1861 agattgagtt attatggaaa atctggtgag gaggcaagtg ctcctttgga ttatgagatg
     1921 aaagcgcacg ttagttatct ttcaatggga gaaaagcggt ttgtttataa taacggtgag
     1981 aatcccgtat ccactcagta tttgactgat ccgattttag tggtattcac gccgacttct
     2041 acaggtgata gttttatatc cttatctagt tggtctatca atgctggaaa acaactcttt
     2101 atcaaaggat atgagagtgg gctagaactc ttgaagaaag ctggaattta tgagcaagta
     2161 tcctatctta aagaaggaag aagtgtttat ctaactcgtt ataatgaagt tcaaactgaa
     2221 acagcaactt taatcttagg agctattgtg gggatagcta gttccttgtt actattttat
     2281 tctgtcaatc ttctatattt cgagcaattc cgccgagata tcttgattaa acgaatttca
     2341 ggtttacgat tttttgaaac acatgctcag tatatggtta gccaatttgc cagttttgta
     2401 tttggtgcta gtctctttat tttaagcagt cgagacttgg tgattggctt gctcacttta
     2461 ttggtctttc tagctagtgc agttttgacg ctttaccgtc aagcgcagaa agaatctcgt
     2521 gtttctatga caattatgaa aggaaaatag gatgattgaa ctaaagaata tatctaaaaa
     2581 atttggaagc cgtcagctat tttcagatac gaatcttcat tttgaaggtg ggaaaattta
     2641 tgccttaatc ggtacaagtg gctgtggtaa gacaacactc ttgaatatga ttggacgatt
     2701 ggagccatat gacaaagggc aaatcatcta tgatggcact tctcttaagg acatcaagcc
     2761 ttctgttttc tttagagatt acttaggata cttatttcaa gattttggct taattgaaag
     2821 ccaaaccgtc aaagagaatc tcaatctgag tttagttggt aaaaagttga aggaaaaaga
     2881 gaaaatctct ttgatgaaac aagctctaaa ctgtgtaaac ctctcttatt tggatttgaa
     2941 gcaacctata tttgagttat caggaggaga agcacaacgt gttgcactag cgaagataat
     3001 tttaaaggat ccgcctttga ttcttgcaga tgaaccaacc gcttccttag accccaaaaa
     3061 ttctgaggaa ttactttcca tcctagaatc tttaaaaaat ccgaatcgga ccattattat
     3121 tgcgacccac aatcctctga tttgggagca agtggatcag gtcattcgag ttaccgattt
     3181 atcacataga tgatatggta agattcagtt agaagaaaga gtcacaaaca cactttgtgg
     3241 cttttttatt tccataaaaa tggtaaaata gtaggagtag aaatggagtt cgagacatga
     3301 aagtaataga tcaatttaaa aataagaaag ttcttgtttt aggtttggcc aagtctggtg
     3361 aatctgcggc tcgtttgttg gacaagttag gtgccattgt gacagtaaat gatgggaaac
     3421 cattcgagga caatccagct gcccaatgtt tgctggaaga agggatcaag gtcattacag
     3481 gtggccatcc tttggaactc ttggatgaag agtttgccct tatggtgaaa aatccaggta
     3541 tcccctacaa caatcccatg attgaaaagg ctttggccaa gggaattcca gtcttgactg
     3601 aggtggaatt ggcttatttg atttcagaag caccgattat tggtatcaca ggatcgaacg
     3661 gtaagacaac cacaacgact atgattgggg aagttttgac tgctgccggg caacatggtc
     3721 ttttatcagg gaatatcggc tatccagcta gtcaagtggc ccaaactgcg tcggacaagg
     3781 acacgcttgt tatggaactt tcttctttcc aactcatggg tgttcaagaa tttcatccag
     3841 agattgcggt tattaccaac ctcatgccaa ctcatatcga ctaccatggg tcattttcgg
     3901 aatatgtagc agccaagtgg aatatccaga acaagatgac agcagctgat ttccttgtct
     3961 tgaactttaa tcaagacttg gcaaaagact tgacttccaa gacagaagcc actgttgtag
     4021 cattttcaac acttgaaaag gttgatggag cttatctgga agatggtcaa ctctacttcc
     4081 gtggtgaagt agtcatggca gcgaatgaaa tcggtgttcc aggtagccac aatgtggaaa
     4141 atgcccttgc gactattgct gtagccaagc ttcgtgatgt ggacaatcaa accatcaagg
     4201 aaactctttc agccttcggt ggtgtcaaac accgtctcca gtttgtggat gacatcaagg
     4261 gtgttaaatt ctataacgac agtaaatcaa ctaatatctt ggctactcaa aaagccttgt
     4321 caggatttga caacagcaag gtcgtcttga ttgcaggtgg tttggaccgt ggcaatgagt
     4381 ttgacgaatt ggtgccagac attactggac tcaagaagat ggtcatcctg ggtcaatctg
     4441 cagaacgtgt caaacgggca gcagacaagg ctggtgtcgc ttatgtggag gcgacagata
     4501 ttgcagatgc gacccgcaag gcctatgagc ttgcgactca aggagatgtg gttcttctta
     4561 gtcctgccaa tgccagctgg gatatgtatg ctaactttga agtacgtggc gacctcttta
     4621 tcgacacagt agcggagtta aaagaataaa atatgaaaaa aattgtcttt acaggtgggg
     4681 ggacggttgg acacgttacc ctcaatcttt tgttaatgcc caagttcatc gaagatggtt
     4741 gggaagtcca ctatatcggg aacaagcgtg gtatcgaaca ccaagaaatc cttaagtcag
     4801 gtttggatgt cactttccac tccattgcga ctgggaaatt gcgtcgctat ttctcttggc
     4861 aaaatatgct ggacgtcttc aaagttggct ggggaatcgt ccaatcgctc tttatcatgt
     4921 tgcgacttcg tccacagacc cttttttcaa agggaggttt tgtctcagta ccgcctgtta
     4981 tcgctgcgcg tgtgtcagga gtgcctgtct ttattcacga atctgacctg tctatgggct
     5041 tggccaataa aatcgcctat aaatttgcga ctaagatgta ttcaaccttt gaacaagctt
     5101 cgagtttggc taaggtcgag catgtgggag cggtgaccaa ggtttcggac aaaaacactc
     5161 cagaaccaga tgaattggtg gatattcaaa cccactttaa tcccaaattg ccaactgtat
     5221 tgtttgtcgg cggttctgca ggcgctcgtg tctttaacca attggtgaca gaccataaga
     5281 aagaactaac agagcgctac aatattatca atctaactgg agattctagt ctgaatgagt
     5341 tgaggcaaaa tctttttcgt gttgactatg tgaccgatct ctatcaaccc ttgatggaat
     5401 tggctgatat tgttgtgaca cgaggtggtg ccaatacgat ttttgagctc ttggcgatag
     5461 caaaattgca tgtcattgtt ccgcttggtc gtgaagctag tcgtggtgac cagattgaaa
     5521 atgcagctta ctttgtaaaa aaaggctatg cagaagacct tcaagaaagc gatttgacct
     5581 tggatagttt ggaagagaag ctttctcact tactaagtca caaggaagat taccaagcta
     5641 agatgaaagc ttctaaggaa ttgaaatctc tagcagattt ttatcaattg ttgaaaaaag
     5701 atttatcata aggaaagtaa atgtcaaaag ataagaaaaa tgaggacaaa gaaaccctcg
     5761 aagaattgaa agagttatca gaatggcaga aacgaaacca agaatatcta aaaaagaagg
     5821 ctgaagaaga ggcggctcta gctgaggaga aggaaaagga aagacaagct cgaatgggag
     5881 aagaatctga gaagtcagag gataaacagg accaggagag tgaaacagac caggaagatt
     5941 cagaatcagc taaggaagag tctgaagaaa aagtagcatc ctcagaggct gacaaagaga
     6001 aagaagagaa agaagaacca gagtctaaag agaaggagga acaggataaa aagctttcta
     6061 aaaaggctac aaaggaaaaa ccagccaaag caaagattcc tggtatccat atcttgcgag
     6121 ccttcacgat tttatttcca agtctgcttt tattgattgt ctctgcctac ttgctcagtc
     6181 cttatgcgac catgaaagat attcgtgttg agggaacagt gcaaactaca gctgatgata
     6241 ttcgacaggc ttcaggcatt caggattcgg attatacgat taatcttctg ctagacaagg
     6301 caaaatatga aaagcagatt aagtctaact attgggttga atcagctcaa cttgtctatc
     6361 aatttccaac taagttcact attaaggtca aggaatatga tattgtggcc tactatattt
     6421 ctggtgaaaa tcattatcct attctttcca gtggtcagct tgagactagt tctgtgagtc
     6481 tgaacagttt accagaaact tatttatcag ttctctttaa tgatagtgaa caaatcaagg
     6541 tttttgtctc agaacttgct caaattagcc cagaactcaa ggcggctatc caaaaggtgg
     6601 aattagcccc aagcaaggtg acatccgatt taattcgatt gaccatgaat gattcggacg
     6661 aagtcttggt tcctctatct gaaatgagta agaaactgcc atattacagt aagattaagc
     6721 cacaattgtc agaaccgagt gtggtcgaca tggaagctgg aatttacagt tacactgtgg
     6781 cggataaatt aattatggag gctgaggaaa aagccaaaca agaggccaag gaagccgaga
     6841 aaaaacagga agaagaacag aaaaaacaag aggaagagag caattgaaat caaacgaccc
     6901 agcgctcatc gcgtcgctag gtttaccttt tctcttatag ttctttagtg accatgtttt
     6961 tacttgacaa gtgctagtag aaataataga ataatagaaa acctttaaag cagtccagag
     7021 aggcagctaa ggttagacgg tgaaagggtg gagactaccc atttttcgtg gaaccttgct
     7081 gttggcaggt tccttttttc gtggcttctg ttggccagac tctctcacta gtaaaggtaa
     7141 aaggagaaac ctatgcgaga acatcgtcca atcattgctc ttgattttcc tagttttgag
     7201 gcggtcaagg aatttttagc tcttttccca gcagaagaaa gcctttatct caaggtaggg
     7261 atggagcttt attacgcagc ggggcctgag attgtgtcct acttaaaagg tttgggtcat
     7321 agtgtctttt tggatctcaa acttcatgac attcctaata cagtcaagtc agcaatgaag
     7381 atcctatctc agcttggtgt cgatatgacc aatgttcatg cggctggtgg tgtagagatg
     7441 atgaaggctg cgcgtgaagg tcttggaagt caagctaaat tgatcgctgt aactcagctc
     7501 acatcaacgt cagaagctca gatgcaggag tttcaaaata tccaaaccag tctgcaagag
     7561 tctgtgattc actatgccaa gaagacagct gaagctggct tggatggtgt tgtttgctcg
     7621 gctcaggaag tacaagtcat caagcaggct accaatccag attttatctg tctgacacca
     7681 gggattcgtc cagctggtgt tgcagttgga gatcaaaaac gagtcatgac acctgctgat
     7741 gcctatcaaa tcggcagtga ctatatcgta gtgggacgtc ccattatcca agctgaggat
     7801 cctgttgcag cttatcatac catcaaggat gaatggacac aggactggaa ttaaagaact
     7861 agattagaaa aataaaagga gaataccatg acacttgcta aagatatcgc tagccacctc
     7921 ttgaaaatcc aagccgttta cctcaaacca gaggaaccct tcacttgggc atctggtatc
     7981 aagtcaccga tttacactga taatcgtgtg acactagcct atccagaaac tcgtacccta
     8041 attgaaaatg gttttgtgga tgctatcaaa gaagcctttc ctgaagtaga agtgattgca
     8101 ggaactgcaa cagcagggat tccacacgga gccattattg ctgataagat gaacttgcct
     8161 tttgcctaca tccgtagcaa accaaaagac cacggagctg gtaatcaaat cgaaggtcgc
     8221 gtagctcaag gtcaaaaaat ggtagtggtt gaagacctta tttcaacggg tggttcagtt
     8281 cttgaagctg tagcagcagc caagcgagaa ggagcagatg tacttggagt tgtagcgatt
     8341 ttcagctacc aattgccaaa agcagataag aactttgcag atgctggtgt taaacttgtg
     8401 acgctttcaa actatagcga gcttatccat ctagcccaag aagaaggtta catcacgcca
     8461 gagggccttg atcttctaaa acgctttaaa gaagaccaag aaaattggca agaaggttag
     8521 gtcagtaaga taaagagaga cgaggctacc gagcctcttt taccatttta tttaaaatat
     8581 gacaatattt taaataaaat aattgacaac gctttctttt attgatataa tgaaaatgta
     8641 atatgtatca aattgatcaa tcaactatct tgtttatcac ttcttaagag gacgatgtca
     8701 tgaaaagaag aaaaagatat tccttttttg cgtagttaca attgcatcta gtttgtttct
     8761 ccctacagtt ttagctagac agattggaaa ttatgattta acgttgccgc gttggggttc
     8821 ggatacaact agtgagcttg agaaagaaaa cgcctctgct ggaattaata atagtgacag
     8881 cactggtggc ggtaaaaggt taagtacctc tattcgtagc gcctatagtg ggtcagatat
     8941 taccccggta tattcattgg ggtctggctc taggattgtc atgtactata atggaggtgg
     9001 tgacaattat attggttctg gtactagatt agctatggcg ccacaatttg gaaatcatgt
     9061 aagaattcat acttcaggtt cttggagtcc agattcttat taacttactt gtcagagtaa
     9121 gccttaaaga tggttgattg tgggtgtagc atgaaaaaag aatgctacac cctattttta
     9181 ttataaggag gagtaaggat ggaatttttc atttgtaatc ttgtacgagt cgttcaatca
     9241 cctcgatttt atatgtcttt atttttgacc cttctttgca tgagtttagg aaatttcctt
     9301 gctttcaatg gtatttataa aattgaaggt ttatcgattt tttttgccgc ttcttctatt
     9361 cgaggatttt caccgattag cctagtagct gcacttatct gtacactgcc ctattctagt
     9421 cagataatag aggatgctga gagtcatttt ctaacagcac aattgtgccg aatttctaaa
     9481 aagaggtatc tagctattgt aggtagtact gcaattattt cttcttttct agtctttttt
     9541 ctcccctatt tattattatt aggaattaat cttttagtga ctccttatca ggaaatttat
     9601 attggagatt atagtggtgc cttaaaagaa ttatttgatt ctaatcagtt gctctatagt
     9661 cttgtggcga ctctttggta tggagtttgg ggcgctgtgt tctctatttt tggactagct
     9721 agtgctttgc tagtgaagaa aaaaatagga gctattttca tcccagttac ctatatgatg
     9781 gttggtggta ttttttgggc tattttaggg ctatcttact tagaacctgt gacaacatta
     9841 gctttgggat atcagaaaga tatcagtctt tccttagtta gtgggcatct tgcttttatt
     9901 ttatttgtta gttgtttggt tgtttatggt acattttttc tacattcaga ggactatgta
     9961 taatgaaaca atttgttcaa ttttataaaa aagatttctt agcagtattg gtttatttta
    10021 tattactgct atcctgtgtt ttatctagta cagtatattt attgcgctgt cgccaatatt
    10081 caatccatcc aaatgtatta gaatggattt tagttttact tcaagatatg acgactggag
    10141 tatattgctt tccgttcaca tatatattgt tcttttttta tttgatgaat aactatttta
    10201 ataggttgga gtgtcgcatt cgtctgaaat caattaagca ctttaccagt tttagtttca
    10261 aattagcagc tcttagtacg gggatttgga cggcgacttt atttttattg atttttctaa
    10321 ttgcatttag taatggtttt agcttctctt tggagataaa ggaggttgat tttttaggag
    10381 aattttatgg tataagtatt gcaaacaatg ctagtttctt tataggattt tttttctctt
    10441 atatagcata ctatttcttt ttatccttac ttactattag cagtttttct tggtttaaaa
    10501 aatcaaacat gagcttagta tttctgttta cttttttatt tgtagaatcc ttattctgga
    10561 tttatcagtt gaacaatggg ataattggat tattgccaat ttttcagtat atggtaaatt
    10621 ccaatccgta tgcattgatt tattggctta cattactatc tatcataatt ccattgactg
    10681 tattttctgt tcatagaaac tggaggagag tgtaaaagtt ggaaatggga aagttaagta
    10741 gtcacatgtg gaggttgaat cagataatct ataccaagta cttttggggt tatgttcttt
    10801 tttggatatt gatttgttta ggattatggt attggttaga aggaaatgat agacttgtta
    10861 tagaaatttt aaaagggcct aatctgagtc aaaactcttt tttagtctta tctatatggt
    10921 tgcttcattg gtttattatt catacatttt ttctagcagt tgtatatcgt agaagagcat
    10981 ccgatttctt tatggaagtg attcgatttt cttctattaa gctctggatt aggtatcaga
    11041 tttggacctg ttttctttat ggactcattt taatcatggt aaaagttcta gtgattcaat
    11101 ttatgttaca gttagcaaac tgggatatag gagttttgtt tatagttgat tctttgaatg
    11161 cttgtgtgct atccttgctt tgctttatgt tatacgcact aggagcgaat gtacaaatga
    11221 actttgcttg cgttagtttc tttttactca tgattgtgtt tggtggtcta tttgtaggaa
    11281 atcgaactaa ttatctattt tatattttga atcgagggaa tggagatata ggacgagatt
    11341 tatttcttca gttgctattt ttagtctttc tttttaaaag cattttctat ttcactcgtc
    11401 aaaagaggag gtttatagaa tgaatgaaat aattacatta aaaaatattg agttgaaatt
    11461 aaaaaaaaca tgtgtttttc aaaaccttaa ttttagttgt aaacaggggg aaattatagg
    11521 aattactggt gcgaatggct caggtaaaag tgtattgttt aaattaatag ctggtttata
    11581 tagtccgtct tatggagaag tgttaatcaa tggggaaaat attgttcctg agagaaaaat
    11641 tccagctaat ttgggagctt tgattgaaga acctggtttt ataaattatt atagtggctt
    11701 taagaattta caatatttgg caagcatacg aggagtagtt ggtaatcagg aaatcaatga
    11761 tacactgaaa atagttggtc tatatgagca aaaagaccag aaagttaaaa cttattcgct
    11821 aggtatgagg aaaaagctag ggattgctca agcaattatg gagaatccct ctattctttt
    11881 actagatgaa cctatgaatg ccttggataa atcaagtgta gaaaatatga gaacattgtt
    11941 tagagagctc tctagtgaaa aagggacaac aattttgatt gctagtcata gtgaagagga
    12001 tattcgtatc ttatgtgata aagtatatgc aatagaagat aaagtatgta cactgtgttc
    12061 agattgaaca tcttagatag actcaggatg ttataggtaa aatcttaaaa agggattgga
    12121 gcttaaaatc cagtcccttt taagagttaa tggccacctt caacaaccag gtcatctgct
    12181 ttagcagcgt caccgtaggt tgggtgaagt gttttttcat aggccttgtg gaagaagttt
    12241 tccttgccta atttttcaat atctttattg atgaagtcta gcaattcttg gttgtctttt
    12301 tgaactgctg ccgcaatggt atcgggatca ccgagggaag taattcctac ttcaaatcct
    12361 ttattttcaa gcgcccaagc tagaacttcc gtattgtcag ttgaaaaggc atctccacgt
    12421 ccgtcaagaa gagcttggta agagtcactg tattggtcgt atttttggag tttgatttct
    12481 ggatgattct tttcaaaata agtctcagca gtcgttcctt ttgtgacaat taaggtttta
    12541 ccttcaagtt gtttgacgtc tgtaatgaga ccagtcttag gtgatacgac acccagagaa
    12601 actttcatat atggaagggc aaaatcaact tgtttcttac gttcgtcagt tactgtaaag
    12661 ttagcaagag taatatctac cttgtttgaa atcaagtatt ccgcacggtt ggcggcatcg
    12721 actgaaatgt atttaacctt gacaccaagg tcttgagcta gttggttccc tagttcaata
    12781 tcgtagcgta gccttggtaa gaaccatcat tgtcaacgta gccaaacggt tttttatctc
    12841 caaacacggc gattcgcagt tcaccgcttt ttttgatttc atcgatagtg cgagctttgg
    12901 cagttgtttt tccagaggat gaaccagcgt ttccacctga gctacaagca gtgataaaga
    12961 taagggcaaa ggcaagtgct aaaacagtta agagtggttt gaatagtttc ataagaatct
    13021 cctttataga tatgagccga attggctaaa gtcaaagacg tttaaaaatt cctgggctcg
    13081 tttggtttgc agattggtaa agaaggcttg agctgttcct tcttcagcga ttttcccttg
    13141 gtcgaggaag ataatccggt cagtaatggc ttgggcaaac tgcatttcgt gggttactaa
    13201 aatcatggta cggccttctt gggccaaatc attgataagt tccagcacct cacgcaccat
    13261 ttctggatcc agcgaagcag tcacctcgtc aaaaaggatg atttctggat gcattaggag
    13321 ggcacggaca attgcaacac gttgcttctg tccaccagat aattgacggg caaagctatg
    13381 ttgtttatcc agcaaaccga cacgctctag taattgcaaa gcttcttccg ttacttcttt
    13441 cttgtccctt ccttgagctt tgatagggcc taggatgagg ttttgtaaga catccagatg
    13501 gggaaagagt tcataacttt gaaagaccat gccaatcttt tggcgaacta ggtgaaaatc
    13561 ttttttattt tcaacgatag actgaccatc cagaagaata tctccacctt gaatactttc
    13621 taagccgttg aggcaacgaa ggagggtact tttcccacaa ccagatggcc ctaggatgac
    13681 aacaacttcc cttttttgat ttctagagaa agtccttgga ggatgggatt gtctccgaag
    13741 gattttttta gttccttgat ttctaagata gtttcagaca tttagtttct ccaatgtttt
    13801 tctaagtgag tggatagttt ggaaataggg tagcaaactg cgaaatataa gactagaatg
    13861 gttccataaa tccaaaatga agcagttggg atggtcaggc gattgctatc gatgatttgt
    13921 tgtccaactt tggtcacttc cacaacccca atcaaaacaa ctaatgaagt ggttttaatc
    13981 atccgagtga caagattgat agcctgcggt agcagtcttc ttaagacttg tgggatgatg
    14041 atgtggtagt aaagttgaac attagtcaag ccgagtgcct attcactttc aaactgatgt
    14101 ttagggagag aagtgatagc tccacgtacc aagtctccca tttcagctgt tccccagagg
    14161 gtaaaaatga taatagctga agtctcacct gagatattga tattaaagtt tcgagccaag
    14221 ccaaagtaaa cgatgaagag tagcaccagc tggggcatga tacggataaa ttccagatac
    14281 aatcgtgtta aaaatcgtat gattctagaa tgggaggtca tgatgattcc catgactgtt
    14341 ccgaacatca tggataagag gacagacagg atggatatcc caatcgtaac gcccaacccc
    14401 tgtaagattc tcaggagatt atttccttga aagagtactt ggattcccga atcctgcatg
    14461 gcgggtcctc ctttctatcc agctaaagac cagtgagatg ggtagcagca tgatcagata
    14521 agcaactacc aacatagcta gcgcaatgtc tgtctcatag tagagaccaa tcaaatcctt
    14581 ggcgacgtac atgaggtcgg ccaaagccac tgctgagaaa acagaggttt ccttgataag
    14641 gaaaatgaca ttggcactaa aggaggggag tgccaccgct gttgcttgcg gaagaaccac
    14701 atagcgaaag acctgtagag gtgtcagacc aatagcgagg ccaatctcct gctgggtttg
    14761 actgatggct tccagcccac ttcggaaaga ttctgccata taggagcctc ctaaaaagac
    14821 aagcccaagc gttgcacaga cttctgaaga taggacaatc ccgattcggg gaagaccgaa
    14881 gtagagaaag aagagttgaa tcaaaagggg cgtattacgt gacaattcaa tgtaggctgt
    14941 cgctacttgc gccaaaacag ggattcgata atgtcggatg atactaacga ttaaaccgag
    15001 cagaaaggat cccaaaattc cccaaactgc aatatgcaag gtcagaaaga atgccttttg
    15061 atatagtggt agatattgtt caacaatgga ccaatccaaa aatagaacct cccatctaga
    15121 aataatacag ttattgtagc acttaaaatc ttctttggat aatatctatt ttttattgcc
    15181 gttataagga tttttatcat agacataaaa tttctgaaat ttccaaacaa aatattttaa
    15241 aagttttgaa aaaagagtta agatattttt ataatacaca aagtaaacgc ttacttatta
    15301 aggaggaca
//
LOCUS       DAVLIK010000043        14173 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLIK010000043 DAVLIK010000000
VERSION     DAVLIK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.043"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            97..894
                     /locus_tag="VXE87_001608"
     CDS             97..894
                     /locus_tag="VXE87_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0843130.1"
                     /translation="MISSEFISKIEFACNKKEGLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSTAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1042..2302
                     /locus_tag="VXE87_001609"
                     /pseudo
     CDS             1042..2302
                     /locus_tag="VXE87_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2398..3672
                     /locus_tag="VXE87_001610"
     CDS             2398..3672
                     /locus_tag="VXE87_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0843131.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKEHDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3682..4560
                     /gene="truB"
                     /locus_tag="VXE87_001611"
     CDS             3682..4560
                     /gene="truB"
                     /locus_tag="VXE87_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0843132.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4801..5103
                     /locus_tag="VXE87_001612"
     CDS             4801..5103
                     /locus_tag="VXE87_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0843133.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5211..5849
                     /gene="udk"
                     /locus_tag="VXE87_001613"
     CDS             5211..5849
                     /gene="udk"
                     /locus_tag="VXE87_001613"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0843134.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5977..7317
                     /locus_tag="VXE87_001614"
     CDS             5977..7317
                     /locus_tag="VXE87_001614"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0843135.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLIIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7295..7507
                     /locus_tag="VXE87_001615"
     CDS             7295..7507
                     /locus_tag="VXE87_001615"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0843136.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7504..8379
                     /locus_tag="VXE87_001616"
     CDS             7504..8379
                     /locus_tag="VXE87_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0843137.1"
                     /translation="MKKQEKLALVESVLEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIASLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIVFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8372..9187
                     /locus_tag="VXE87_001617"
     CDS             8372..9187
                     /locus_tag="VXE87_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0843138.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9180..9611
                     /locus_tag="VXE87_001618"
     CDS             9180..9611
                     /locus_tag="VXE87_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0843139.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9618..11285
                     /gene="recN"
                     /locus_tag="VXE87_001619"
     CDS             9618..11285
                     /gene="recN"
                     /locus_tag="VXE87_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0843140.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSEIYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11287..12015
                     /locus_tag="VXE87_001620"
     CDS             11287..12015
                     /locus_tag="VXE87_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0843141.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12094..13917
                     /gene="lepA"
                     /locus_tag="VXE87_001621"
     CDS             12094..13917
                     /gene="lepA"
                     /locus_tag="VXE87_001621"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0843142.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13998..>14173)
                     /locus_tag="VXE87_001622"
     CDS             complement(13998..>14173)
                     /locus_tag="VXE87_001622"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843143.1"
                     /translation="ETDEVSSKHGFEVVDETDEVSSKHGFEVVDETDEVSNHTYGKAT
                     MTWFEEIFEEYKN"
BASE COUNT         4189 a         2592 c         3366 g         4026 t
ORIGIN      
        1 tcaatctact ataaactttt atgaaataca gaaaacgctt cctaaaacct aaagtttgtg
       61 atataattat caagaaaaaa gatttaggag tttattatga tttcttcaga atttatctca
      121 aagattgaat ttgcttgcaa taagaaagaa ggtctttata gtcaaagcaa atttaagtat
      181 gcgattcgtt cgatgttcgc aggtgcattt ttaaccttca gtactgctgc aggtgcagtt
      241 ggggctgact tgattaataa aattgcacca ggtagtggac gcttcctctt tccattcgtt
      301 tttgcttggg gcttggccta cattgttttt ttgaatgccg agttggtcac ttcaaacatg
      361 atgttcttga ctgctggtag tttcttaaaa aaaatctctt ggagaaaaac agctgagatt
      421 ttactatact gtaccttgtt caaccttatc ggagccttga tagcagggtg gggctttgct
      481 cattcgacag cctatgcgaa tctgacacac gatagtttca tctcaggtgt tgttgagatg
      541 aagttaggcc gctcaaatga attggtcttg cttgaggcga ttttggcaaa tattttcgta
      601 aatattgcga ttctgtcatt tattttggtc aaagatggtg gtgccaaact ttggcttgtg
      661 ttgtcagcta tttacatgtt tgtattctta acaaacgagc acattgcggc gaactttgct
      721 tctttcgcga ttgtgaaatt cagtgttgct gcggattcaa ttgccaactt cggtgttgga
      781 aatatgcttc gccactgggg tgtgactttc atcggaaact ttatcggagg aggcctcttg
      841 atgggtcttc catatgcctt cctcaataaa aacgaagata cttatgtaga ttaagaaaat
      901 gagcacgatt gagtcgtgct tttttcattt tcaaaataag gtaacagcta tttcttatat
      961 caaaatatag aaaactgata tttgtaaact ataactcaag gtgctacaat atccttaata
     1021 aaataatatg gaggtcacct tatgacttgt gattttaaat ttgaaactct acaactacat
     1081 gctggtcaag ttgtggctcc agctactaag tctcgtgcag tgccgattta atcaaacaac
     1141 attttttgtt tttgatgaca cgtaggaagg tgccgatatg tttgccttga ggaaaccagg
     1201 gaacatttat actcgtatca ccaatcctac aacagctgcc cttgaaggtg gtgttgaagc
     1261 gctagcaaca gcatcaggta tgactgcagt gacttatacg attttggcgc ttgcccatgc
     1321 tggtgaccat gtagtggctg cttcgactat ttacggtgga accttcaatc ttttgaaaga
     1381 accccttcct cgttatggta tcacaacaac ctttgtcgat attgataatt tggaggaagt
     1441 agaagcagct atcaaagaca ataccaagct tgtcttgatt gaaaccttgg gtaacccctt
     1501 gattaatatt ccagacctgg aaaaactggc agagattgct cataaacatc aaatcccact
     1561 tgtgtcagac aatacttttg caacacctta tttgattaac gtcttctctc atggcgttga
     1621 cattgccatt cactctgcga ctaagtttat cggtgggcat ggtacaacta ttggaggaat
     1681 aattgtcgat agtggtcgtt ttgactggac ggcttcaggg aaattccctc aatttgttga
     1741 cgagggtcca agctgccaca atttgagcta tactcgtgat gtgggtgcag cagcctttat
     1801 tatagctgtt cgagttcaat tgcttcgtga tacaggtgca gccttgtcac cattcaatgc
     1861 tttcctcttg ctacaaagac ttgaaaccct ttcacttcgt gtggaacgcc atgtacaaaa
     1921 tgctgagaca attgttgatt ttcttgtcaa ccatcctaag gtagaaaaga taaattatcc
     1981 aaaacttgca gatagtcctt atcatgcctt ggctgagaaa tacttgccaa aaggtgtcgg
     2041 ttcaatcttt accttccatg tcaaaggtgg cgaggaagaa gcacgcaagg tcattgataa
     2101 tttggaaatc ttctcagacc ttgctaacgt ggcagatgcc aagtctcttg ttgttcatcc
     2161 agcaacaacc actcatggtc aattgtcaga aaaagaccta gaagcagcag gtgtcacacc
     2221 aaatcaaatc cacttgtcta tcggacttga aaatgtagat gatttgattg aagacttgcg
     2281 cttggccttg gaaaaaattt aaagaaaaag aagataaaca gtggttttcg actcgctgtt
     2341 tttgattttc cttcatgcat gatataatgg ttacagaagt ctagaaagag gaatgtaatg
     2401 aacgaaatca aatgtcccaa ctgtggggaa gtctttacag taaatgaaag ccagtatgct
     2461 gaacttttgt cccaagtgag aacggcagag tttgataagg aactacacga taggatgagg
     2521 caggaactgg ccttggctga gcaaaaggct atgaatgagc aacagactaa actggctcag
     2581 aaggatcaag aaattgcgca attacagagt cagatccaaa actttgatac agaaaaagaa
     2641 ttggccaaga aagaagttga acagacaagc catcaggcct tattggctaa ggacaaggaa
     2701 gtacaggctt tggagaacca attggccact ttgcgtttgg agcatgaaaa tcaactgcaa
     2761 aagacccttt ctgacctaga aaaagaacat gatcaggtca aaaatcagct cctcttgcaa
     2821 gaaaaggaaa atgagttgtc tttggcttct gttaagcaaa actatgaagc ccagcttaaa
     2881 gcagctagtg aacaagtcga gttttataag aattttaagg ctcaacaatc tacaaaagcg
     2941 attggggaaa gcctagaaca gtatgcagag agtgagttta acaaggttcg tagtttcgcc
     3001 tttccaaatg cttactttga gaaggataac aaggtctctt cgcgtgggtc taaaggggac
     3061 tttatcttcc gtgagtgtga tgaaaatgga gttgaaatca tttctatcat gtttgagatg
     3121 aaaaacgaag cggacggaac agagaagaag cacaagaatg cagattttta caaggaattg
     3181 gacaaggacc gtcgggagaa gaactgtgag tatgccgttt tggtgaccat gcttgaggcc
     3241 gataatgact actttaacac agggattgtt gacgtcagcc acgagtatga aaaaatgtat
     3301 gttgttcgtc ctcaattctt tatccagttg attggtctct tacgtaatgc ggcgctaaat
     3361 tccctaaaat acaagcagga gttggccttg gttcgcgagc aaaatattga cattacgcat
     3421 tttgaggaag atttggatgc ctttaagcta gcttttgcta agaactataa ttcagcttcg
     3481 actaactttg gaaaagctat tgatgaaatc gacaaggcca tcaaacgcat ggaagaggtt
     3541 aagaaattcc tgaccacatc tgaaaaccaa ctccgtctag ctaacaacaa attggaagat
     3601 gtctctgtta aaaaattgac ccggaaaaat ccaacaatga aagcgaagtt cgaagcactg
     3661 aagggggagt agaaagcaaa aatgaacggt attatcaact taaaaaaaga agcaggaatg
     3721 acctcgcatg atgcggtttt taaactgcgt aagattttgg gaaccaagaa aattggtcat
     3781 ggtggaacct tggatccgga tgtggtgggt gttttgccga ttgcggttgg caaggcgaca
     3841 cgcatggtcg agtttatgca ggacgagggt aagatctatg agggggaaat tactctgggt
     3901 tattccacga cgactgagga tgctagtggg gaagtgatcg cagaaacccc tgttttgtct
     3961 cccttggatg aaaagcttgt tgatgaagcg attgctagct tgactgggcc tattacccag
     4021 attcccccta tgtattcggc agttaaggtt aatggtcgca agctctatga gtatgcgcgt
     4081 gctggtcagg aagtggagcg tccagaacgt caggtgacca tttatcaatt tgagcgaaca
     4141 agtccgattt cttatgatgg ccaacttgcc cgattcactt ttcgtgtaaa atgcagtaaa
     4201 gggacttaca tccgtacttt gtcagttgat ttgggtgaaa agcttggtta tgcggctcat
     4261 atgtcccatt tgactcgtac tagtgctgct ggcttacaat tagaagacgc tcttgccttg
     4321 gaggaaattg ctgaaaaagt agaggctggg caattagatt ttctccatcc tttagagatt
     4381 gggacaggtg accttgtcaa agttttccta actccagaag aggctacaga agttcgcttt
     4441 ggtcgtttta ttgagctaga ccaaacggac aaagaactgg ctgcctttga agatgataaa
     4501 ttgttagcca ttctagaaaa acggggcaat ctctataagc caaggaaggt ttttagctag
     4561 atcgtttagg aataaaaatc gggtgataga taacaattgc ttgataaaac cccatactaa
     4621 tagtagaatg gttttgggaa ttataatatt ccaattgttg cgagttgtag gtactcaaat
     4681 aatctatata gaaatttaga ggtgtgaaat gaagcaattt aaaattcttt cagataaata
     4741 tttagagtcc attacaggtt ctggtgggaa cttaggccca ggatttggtg tgataattcc
     4801 atgatgcgaa atgagtttcg agaaagggtg gagcaacttc ttcaacaaaa agaaataaat
     4861 gaaaatagtg agttgagtca cctgtttcgt cttgctatac aaaatttaga cagaaatgaa
     4921 aaataccaaa cggtcatggc caatttgagt caagggttgt cactttacct catgacgcat
     4981 cattaccagg cacctaagtc tgtcattgat tttggtttat ggattgccaa agctcctagc
     5041 caggaaagag ggagactggc tttcttgcag atgcttgctc aaaccctaca gggctttcgt
     5101 taaaactgtc gaacatcaga gggaagactc tggtgttttt tgctgatgag actataaatt
     5161 ttgtaaaaaa tgtgatagaa tagacgacgg ataaaataac ggaggatagc atgcaaaata
     5221 gaccaatcat tattggagtg acaggtggtt ctggtggtgg taaaaccagt gtttcaagag
     5281 ccattttatc gcattttcct gatgaaaaga tttccatgat tgagcatgat tcatactaca
     5341 aggatcagtc tcatttgacc tttgaagagc gtgtcaaaac caactatgac catccttttg
     5401 cctttgatac agacttgatg atcgagcaga ttaaggaatt gttggcaggg cgtccggtgg
     5461 acatcccgac ctacgactat acagagcata cacggagtag caagacctat cgtcaggagc
     5521 ctcaagatgt ctttatcgtt gagggcattt tggtcttgga ggacaagcgt ctgcgcgatt
     5581 tgatggatat caagattttt gtggatacgg atgacgatgt gcgtattatt cgtcgtatca
     5641 agcgtgatat ggaggaacgt ggccgtagcc ttgatagcgt tattaaccag tacttaggtg
     5701 tggtcaaacc aatgtaccac cagtttatcg agtcaactaa gcgttatgct gatatcgtca
     5761 ttcctgaagg ggttagcaat accgtggcta tcgacctgtt gacgaccaag attgcaaaga
     5821 ttttggaaga agctcgaaac agcaaataat cacatgtgga ggccttgcct cctttttcta
     5881 tttttccctc ataatggtac ataaatggag atttttaggc atatttttgg tataataata
     5941 cccataaaag agcaagtaaa tgaatagtag gtggagatgg aaaagtattt atcggtaaca
     6001 actttgacca aatatctgaa aatgaaattc gataaagacc catacttgga acgggtctat
     6061 ttaactggtc aagtttccaa ctttcgtaaa cgacctactc accaatattt ctccctaaag
     6121 gatgaccatg cagttattca agcgaccatc tggtctggga tttatcagaa attagggttt
     6181 gacctggaag aaggaatgaa gatcaatgtg attgggcgtg tacaggtcta tgaaccaagt
     6241 ggtagctact ccatcatcat tgaaaaagct gagcctgatg gggttggggc gcttgcgatt
     6301 cagtttgaac aacttaagaa aaaattgaca gaagaaggtc tgtttcaaga acgcttcaag
     6361 caagctctac cccaattttc taagagaatt ggggtggtaa ccagccgtag tggagccgtt
     6421 attcgagata ttatcacaac cgtcagcagg cgattcccag gtgttgacat ccttctttat
     6481 ccgaccaagg ttcaaggtga aggggctgcg gaggaaattg ctagaaatat tgcgcgtgct
     6541 aatcaacggg acgatttgga tttgatcatt attggtcgtg gaggtggttc tattgaggat
     6601 ctctgggcct ttaacgaaga aattgtggta cgagctattt ttgaatctcg tttgccagtt
     6661 atctctagtg tggggcatga gacggatgtg accttggcag attttgtggc agatcgacgc
     6721 gctgcaacgc caacagcggc ggctgaactg gcaacacctg tgaccaagtt ggatgtatta
     6781 gctcatttgc aaaatcagga aaaacggatg gcaacggcag tccgaaatgt tctatctaag
     6841 aaacaagagg ctttgaaaaa atgcagtcag tctgttatct ttagacaacc tgagcgcttg
     6901 tatgacggtt atttgcaacg cttggaccaa ctgcaactgc gtttgaaaca aagtttgcga
     6961 actcggattt ctgataacaa acaattagtt caagcaagaa ctcatcaatt agtacaatta
     7021 tcacctgtta ccaaaatcca acgctatcaa gaccgtttag gacagttgga caagctctta
     7081 ggtagccaaa tggcgttagt ttatgacgcc aaggttgctg aggccaagcg actttcggaa
     7141 gctttgctca tgttggatac tagccgaatc gtggcgcgtg gttatgctat tgtcaaaaaa
     7201 gaagagtcca ttgtagattc ggttgagagt ttgaagaaaa aagaccaagt aacgcttttg
     7261 atgcgagatg gtcaagtaga attagaggtt aaagatgtca aaacaaaaga aatttgagga
     7321 aaatctagca gaactggaaa ccattgtcca aagtttggaa aatggtgaaa ttgctctgga
     7381 agatgcgatt actgcctttc aaaagggcat ggtcttgtca aaagagctcc aagctacgct
     7441 ggacaaggct gaaaagacct tggtaaaggt catgcaagaa gacggaacag aaagtgattt
     7501 tgaatgaaaa agcaagaaaa attagctctt gtcgagtcgg ttttggaaga tttttatgga
     7561 gaccagcagt ttgcctctag tttacgggag tctgttctct attctattca tgctggtggc
     7621 aagcgtattc ggccttttct cttgttagaa gttctggaag ccttgcaggt tgccatcaaa
     7681 cctgctcacg cgcaggtagc tactgccttg gagatgattc atacagggag cttgattcac
     7741 gatgaccttc ctgctatgga tgatgacgat tatcgaagag ggcggttaac caatcacaag
     7801 aaattcggtg aagctatggc cattttggct ggagatgcct tattcttaga cccatatgcc
     7861 ttgattgcgc aggcagattt gccaagtcag atcaaggtgg acttgattgc cagcttatcc
     7921 cttgcttcag gtagtctggg tatggtggca gggcaagttt tggatatgga gggcgaacac
     7981 cagcacttgt ctctggaaga acttcagact attcatgcca ataagactgg gaagttacta
     8041 gcctatccct tccaagcggc agctattata gctgaattgt cacctgaaat gcaggtgaag
     8101 ctgaaaactg tgggtgaatt gattggactt gcttttcaag tcagagatga tgtactggat
     8161 gtgacagcta gttttgagga aatcggtaag acacctcaaa aggatctgca ggcagaaaaa
     8221 tcaacctatc ctgccttgtt gggcttggaa gagtccattg tcttttgtaa ccaaaccctg
     8281 gatcaagcta atgaaaaatt ggaagaaatt gcccagcagg ttccctttga aacagaatcg
     8341 attgtaagtg tagtagaaag tttgagaatc aatggctaag gaaagagtgg atgtactagc
     8401 ttataaacag gggttgtttg aaacgagaga gcaggccaag cgaggtgtga tggctggcct
     8461 agtcgtagca gtccttaatg gagaacggtt tgacaagcca ggagagaaaa ttccagatga
     8521 caccgaatta aaactcaagg gggagaaact caagtatgtc agccgtggtg gtttgaaact
     8581 ggaaaaggcc ttgcaggtct ttgatttgtc ggtggatggc gcgactacga ttgatatcgg
     8641 ggcctctact ggaggtttta ccgatgtcat gctacagaat agtgccaagt tggtctttgc
     8701 agtcgatgtt ggtaccaatc agttggcttg gaaattacgc caagacccac gagttgtcag
     8761 catggagcaa ttcaattttc gctatgctga aaagactgat ttcgagcagg agccgagctt
     8821 tgccagtatt gatgtgagtt tcatttccct tagtctgatt ttgccagcct tgcaccgtgt
     8881 cttggctgat caaggtcagg tggtagcact tgtcaaacct cagtttgagg caggacgtga
     8941 gcagattggg aaaaatggaa ttattcgaga tgctaagatt catcagaatg tccttgaatc
     9001 tgtaacagct atggcagtag aggcaggttt ttcagtcctt ggcttggact tttctcccat
     9061 ccaaggtgga catggaaata ttgaattttt agcgtatttg aaaaaagaaa agtcagcaag
     9121 caatcagatt cttgctgaga ttaaagaagc agtagagagg gcgcatagtc aatttaaaaa
     9181 tgaataaaaa agaaagactt gaaaaaatta gaagattggt gacagattat caaatcggca
     9241 cgcaagaaga aattgtagaa catttgaaag aagcaggtat cactgccact caggcgacgg
     9301 tatcccgaga tatcaaagag ttaggtattg tcaaaattcc tttgagagac aacacctatg
     9361 tctacgaatt gccaaaatca atcgtaaaaa gtctgcaact ggctgaagac aatatcgaat
     9421 cggctgaatt gatggataag atgatcaatc tccaagttat tccaggaaat acggcttttg
     9481 taaaagctca gttaatcgag acttttgcag acaagatttt tagctgtttg actgatgata
     9541 gctcgatttt agtcattgcc agaagtggaa gtctagcaga ggaaatcttt gaacaagtaa
     9601 aaaattggta ggtctatatg ttacttgaaa tttcgataaa aaactttgcc attattgagg
     9661 ctatttccct caattttgaa aaggggatga ctgtcctgac tggtgaaacg ggtgcaggga
     9721 agtcgattat cattgatgcc atgaatatga tgttgggagc tcgtgcgacg acagatgtta
     9781 ttcgtcatgg tgcaccaaag gcagagattg aggggctttt ctcagttgag aatagtcgtc
     9841 ttttacagga aatttttgat gagcaaggtt tagaattagg tgatgaaatt atcatccgtc
     9901 gggaaatctt gcaaaatggt cgtagtatca gccgtgtaaa tggtcagatg gttaatctgt
     9961 ctgttttgcg agctattggg caacatcttg tagatattca tggtcagcat gaccatgagg
    10021 agttaatgcg tccccaactg catatccaga tgttggatga atttggtgat gccgcttttt
    10081 gggacttgaa agaaacctat caaacgagtt ttgatgccta tcggaaaatg cgcaagcagg
    10141 ttctggaagt caagaaaaac caacaggaac acaaggcacg tatcgaaatg ttggaatttc
    10201 aaatggcaga gattgaggca gcaaacttgc aggctggaga agacttggct ctcaatcaag
    10261 agcgagataa actcctcaac cacaaaaata ttgcggatac actgaccaat gcctacagta
    10321 tgttggacaa tgaagatttt tcaagtctgg ccaatgttcg ttcagctatg aatgacatgg
    10381 aaagtgtcga agagtatgat cctgaatacc gtgaaatttc aagctctctg tctgagatct
    10441 actatgtttt agaagacatt agcaaacgtt tggaagctat cattgaggac cttgattttg
    10501 atggcaatcg cctcatgcag gttgagaatc gtttggacct ccttcatact attactcgta
    10561 agtatggtgg gactgttgat gatgttttgc tttattttgc caagattacg gaagaataca
    10621 atctcttgac aggcaataat ctttcgtctg aggacatgga agcagagctt aagaagttgg
    10681 aagtcaatct tgtcaatttg gcaggtcaac ttgcttctgc tcgtcataat ttggctcagc
    10741 aactcgaagc tgagattaaa caagaactgc aagatcttta tatggaaaaa gcccagtttc
    10801 aggttcgttt tagtaaggga aaattcagtc gtgagggaaa tgaaatggtt gagttttata
    10861 tttcaaccaa ccctggagaa gactttaaac ccttggttaa ggttgcttct ggaggggaat
    10921 tatctcgtct catgttagcc attaagtctg ccttttcacg taaagaaggc aagactagca
    10981 ttgtctttga tgaggtggat acgggagttt caggtcgtgt tgctcaagct attgctcaga
    11041 aaattcataa aattggtcag catggtcagg ttttggctat ctcccatttg ccacaagtaa
    11101 ttgcgattgc agattatcaa ttctttattg agaagattag taatgaccat tcaacggttt
    11161 cgactgttcg tctcttgacg gtcgaagagc gagtggagga agttgccaag atgttggcag
    11221 gtgatgatgt gacagaagca gccctgacgc aagccagaga attgttgaga aacagggaga
    11281 aataagatga cagattatta tgtaattgga gatgttcacg gaaaagctgg gatgctggaa
    11341 gaccttctta aaacctggga tggtcagacc cagttgctct ttctaggtga tttgattgac
    11401 agaggtgagg atagtcaccg tgttcttgaa atggtcaagg acttggtgga caatcaaggg
    11461 gctatctgtt tgtctggaaa ccacgagtat atgtttttga cttggctaga tgacccagaa
    11521 gaaagttatg accattatcg tcgcaatggt ggagatacaa ccattaactc tatcctaggt
    11581 cgtcccttgg atgcaccagt tgatggagta gaagatgcca agcgggttgc cgctgaagcg
    11641 gcagacttgg tcgaattcat tcgtcaaatg ccatttgtag tagagacaga caagtatatc
    11701 tttgttcacg caggtattga tttgaccttg gacgactggc atgaaacaac agattataaa
    11761 aaagtatggc ttagaaaacc attccacgga gctgaaaatc atactggaaa aaccattgtc
    11821 ttcggtcata caccggtcta tggtttgtta cagcaagaac gcggtacatc tgagctttgg
    11881 actacagaag atggcaagat tggaatggat ggaggagctg tttatggtgg tgtccttcac
    11941 gggattgtct ttacagacca aggaatgaca gaacaccact ttatcgaaaa tgacggcttt
    12001 gtcgctgaag attagtactc ctagcagggt atggtcttgt caaaatatca aaaacaattt
    12061 ataataaata gataccctga aaggaagaga atcatgaact tagaagaatt gaaaaaacga
    12121 caggagaaga tccgtaactt ctctattatc gcccatattg accacggaaa atcaactcta
    12181 gcagaccgca ttttggaaaa aacagagacg gtttcaagtc gtgaaatgca ggcccagctt
    12241 ttggatagca tggagctaga gcgggaacgt ggaattacta ttaagttgaa tgccatcgag
    12301 ttgaattaca ctgcaaaaga tggggaaact tatattttcc acttgattga cacaccaggg
    12361 cacgttgact ttacctatga agtttcacgt tcgctagctg cctgtgaggg tgctattttg
    12421 gtggtcgatg cggctcaagg aattgaggct caaactcttg ccaacgttta tctggctttg
    12481 gataatgatt tggaaatcat gcctatcatt aataaaattg acctgccggc tgcagatccg
    12541 gagcgcgtgc gtacagagat tgaagatgtg attggtttgg atgccagtga agcagttttg
    12601 gcttctgcca aggctggtat tgggattgaa gaaatcctcg agcaaattgt agaaaaagta
    12661 ccagcaccaa cgggtgatgt gacggcgcca cttaaggcct tgattttcga ctctgtttac
    12721 gatgcttacc gtggggttat cctccaagta cgtgtcatgg acggagtggt caaacctggt
    12781 gataagattc agctcatgag caatagtaag acctttgatg tggccgaagt cggtattttt
    12841 acaccaaaag cggttggtcg tgatttcctt gcgactggtg atgttggtta cattgcggcg
    12901 tctatcaaga cggttcagga tactcgtgtg ggtgataccg ttaccttggc aaccaatcct
    12961 gcggcagaac cattacatgg ttataagcag atgaatccta tggtctttgc gggtctctac
    13021 ccaatcgaat caaacaagta caatgacctg cgtgaagcgc ttgaaaaatt gcaactgaat
    13081 gatgctagtc ttcagtttga accagaaaca tctcaggcac ttggatttgg tttccgttgt
    13141 ggatttcttg gacttctcca tatggatgtt atccaggaac gtttagagcg tgagttcaat
    13201 attgacctca tcatgacagc tccgtctgtt atttacaaag ttaatttgac cgacggtgag
    13261 tctatggatg tgtctaaccc atctgagttt ccagacccaa ctaagattgc gaccattgaa
    13321 gagccttatg tcaaggcgca aatcatggta ccacaggagt tcgtcggagc agtaatggag
    13381 ctagctcagc gtaagcgtgg ggactttgtg actatggact atattgatga taaccgtgtc
    13441 aatgttatct atcaaattcc tcttgctgaa attgtctttg acttctttga taaacttaag
    13501 tcttcaacac gtggttatgc aagctttgac tacgaattgt cagaatatcg cccatctaag
    13561 ctggtgaaaa tggatatcct tctcaatgga gataaggtgg atgctctcag ctttatcgtt
    13621 cacaaggact ttgcctacga acgtgggaaa ctcatcgttg ataaactcaa gaaaatcatc
    13681 cctcgccaac aatttgaagt tccaatccaa gcggctattg gacacaagat tgtcgctcgt
    13741 actgatatca aggcccttcg taagaacgta cttgctaaat gttatggtgg tgacgtttct
    13801 cgtaagcgta aactccttga aaaacaaaaa gctggtaaga aacgcatgaa atccatcgga
    13861 tcagttgaag ttccgcaaga agccttcctc agcgtcttga gtatggatga agaataagtt
    13921 atcagaaatg cctttccttg ttcacaggaa atttatataa gaatcaatag taaagcaggc
    13981 ttagatggtc tgctttttta gtttttatac tcttcgaaaa tctcttcaaa ccacgtcatc
    14041 gtcgccttac cgtatgtatg gttactgact tcgtcagttt catctacaac ctcaaaacca
    14101 tgttttgagc tgacttcgtc agtttcatct acaacctcaa aaccatgttt tgagctgact
    14161 tcgtcagttt cat
//
LOCUS       DAVLIK010000044        14078 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLIK010000044 DAVLIK010000000
VERSION     DAVLIK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14078
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.044"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(29..838)
                     /locus_tag="VXE87_001623"
     CDS             complement(29..838)
                     /locus_tag="VXE87_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0843144.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            complement(840..2189)
                     /gene="vicK"
                     /locus_tag="VXE87_001624"
     CDS             complement(840..2189)
                     /gene="vicK"
                     /locus_tag="VXE87_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0843145.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     LLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            complement(2182..2886)
                     /locus_tag="VXE87_001625"
     CDS             complement(2182..2886)
                     /locus_tag="VXE87_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0843146.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            complement(2942..4117)
                     /gene="mutY"
                     /locus_tag="VXE87_001626"
     CDS             complement(2942..4117)
                     /gene="mutY"
                     /locus_tag="VXE87_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0843147.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            complement(4445..6115)
                     /locus_tag="VXE87_001627"
     CDS             complement(4445..6115)
                     /locus_tag="VXE87_001627"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0843148.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCALIDVPVELASVWADGVEGGVELAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQVVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            6345..7034
                     /gene="coaB"
                     /locus_tag="VXE87_001628"
     CDS             6345..7034
                     /gene="coaB"
                     /locus_tag="VXE87_001628"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0843149.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            7046..7597
                     /gene="coaC"
                     /locus_tag="VXE87_001629"
     CDS             7046..7597
                     /gene="coaC"
                     /locus_tag="VXE87_001629"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0843150.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            7581..8144
                     /locus_tag="VXE87_001630"
     CDS             7581..8144
                     /locus_tag="VXE87_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0843151.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            8426..8953
                     /locus_tag="VXE87_001631"
     CDS             8426..8953
                     /locus_tag="VXE87_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0843152.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            8965..9480
                     /locus_tag="VXE87_001632"
     CDS             8965..9480
                     /locus_tag="VXE87_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0843153.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(9477..9944)
                     /locus_tag="VXE87_001633"
     CDS             complement(9477..9944)
                     /locus_tag="VXE87_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0843154.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFTGTLQS
                     SEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(10017..10505)
                     /locus_tag="VXE87_001634"
     CDS             complement(10017..10505)
                     /locus_tag="VXE87_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0843155.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIDDLKVVGFISYGSFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LVKVALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(10471..11034)
                     /locus_tag="VXE87_001635"
     CDS             complement(10471..11034)
                     /locus_tag="VXE87_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0843156.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(11044..13032)
                     /gene="uvrB"
                     /locus_tag="VXE87_001636"
     CDS             complement(11044..13032)
                     /gene="uvrB"
                     /locus_tag="VXE87_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0843157.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMTYNEEHDIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKVLD"
     gene            complement(13109..14062)
                     /locus_tag="VXE87_001637"
     CDS             complement(13109..14062)
                     /locus_tag="VXE87_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0843158.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
BASE COUNT         4161 a         3192 c         2517 g         4208 t
ORIGIN      
        1 taaaaagaac accttctcag cgttctttct atatctctgt caatggtgtt gcggtatctg
       61 gtgaggtatc ataaacctta aagtctactc cgactcccag atcagcttga gccagctgat
      121 tgaccatggt catatgagcc agttccttga tattgttttc cttagataaa tgcccaaggt
      181 aaatcttctt agtacgattt cctagcgtcc gaatcatagc ttcagcaccg tcctcgttag
      241 aaaggtgacc aaggtcagat aggattcgtt gtttgagtcg ccaagcgtaa gaacctgatc
      301 gcaaaatctc tacatcatgg ttggcctcga taagatagcc atccgcattt tcgacaatgc
      361 ccgccatacg gtcactgaca taacctgtat ctgtcaaaag gacaaaactc ttgtcatcct
      421 tcataaagcg atagaactgc ggtgcgactg catcatggct tacaccaaaa ctctcgatgt
      481 cgatatctcc aaaagttttg gttttaccca tttcaaaaat atgcttttgc gaagaatcca
      541 ccttgccaag atatttacta ttttccatag cttgccaggt cttttcattg gcataaagat
      601 ccataccata cttgcgagcc aaaacgccta ctccatggat atgatctgaa tgctcatggg
      661 taatcaagat ggcatccagg tcttctggct tgcggttaat ttcagctagc agactggtaa
      721 ttttcttgcc agacaagcct gcatccacta aaagcttctt ttttgaggtt tccagataaa
      781 aagaatttcc actggaaccc gacgctaaaa tactgtattt aaagcctatt tcactcattc
      841 tagtcttcta cttcatcctc ccatacttct tctttcactg catccttatc ataagggagc
      901 acaatggtaa aggttgaacc cttgccgtat tcactcttgg cccaaataaa gcccttatgt
      961 tgtttgataa tttctttagc gatagacagt cctagacctg taccaccttg tgcacgactt
     1021 ctagcacgat ccacacgata gaaacggtca aagatacgtg gtaaatcctg cttaggaatc
     1081 cccaaaccgt ggtcagaaat ggataaaatc atctggtctt cagttgtctt cattctgaca
     1141 gtgattttac ccccatctgg cgaatactta atagcattat ttaaaatatt gtcgacaacc
     1201 tgcgtcatct tatctgtatc aatttccatc cagatagaat tgatgggata atctctcacc
     1261 aactcatatt ttttctcctt ttcctgtcct ttcatcttgt caaaacgatt gaggataaag
     1321 gtaataaaag cagtgaagtt aatcagttcc acatctagga gactggtagc attatcaata
     1381 cgtgaaagat ggaggagatc cgtcaccatg cgcatcatac ggttggtctc atcaagagaa
     1441 accttgataa agtctggtgc tacagtttca cacaaagccc cctcatccaa ggcttcaaga
     1501 taggatttta cgctagtcag aggagtccgt aactcatggc taacattgga aacaaagagt
     1561 cttcgttctc gttcttcctt ctcctgctcc gtcgtatcat gcaaaacagc caccaaacct
     1621 gaaataaagc cagactctcg acgtatcaag gcaaagcgaa ctcgaaggtt caaatattcg
     1681 ccattgatat cttgggaatc tagcaacaat tctggacttt gggtaatcaa atcacgcaat
     1741 tcatagtttt cttctatctt gagcaattcc aaaatgcttc tattcagaac atcttcctta
     1801 accaacccca gttgcttctt ggctgtatca ttaatcatga taatctgacc ccgacggttg
     1861 gtcgcaagaa ccccatctgt catataaaac agaatactat ttagcctctt actctcttgt
     1921 tctagatttt cctgagtgag acgaataacc tccgacaagt cattcaaatt attggtaata
     1981 ttggtgattt cagacccacc ttgcatatca agaaccttgg aataatctcc tgcaatcaaa
     2041 tctttaacct tttgattgat ttgcttcaac tgaatattat cacgtctatt ttccagtaat
     2101 aagagggtca caacaaggat gaaacctaac aaaatcagga taaagataaa atctctggta
     2161 aaaatggttt gtttcagtaa atcaagcatt atttctcatg taatacccta caccacggcg
     2221 cgtcaagata tactctggtc ggctgggcgt atcttcaatc ttctcacgca gacgtcgtac
     2281 agtcacatca actgtacgga catcaccaaa atagtcataa ccccagacag tctcaagcaa
     2341 gtgttcgcgc gtgatgactt gacctgtatg cgatgctaaa tgatacaaaa gctcaaattc
     2401 acgatgggtt aagtctagtt cttcgccata ttttttagcc acgtaggcgt ctggaacaat
     2461 ttctaaatcc ccaatttgga taggttgagg tttactatct gcttcctgac catctactgg
     2521 cataggttga gaacgacgca gaagagcttt aacacgcgcc tgcaactcac gattggagaa
     2581 gggtttcgtt acatagtcat ctgccccaag ttccaaaccg ataaccttat caaattcact
     2641 atctttggct gaaagcataa gaatgggcac actgcttgtc ttacgaatgg tcttagcaac
     2701 ttctaaacca tcaatttctg gaagcatcaa atccagaata ataatatctg gttgctctgc
     2761 ttcaaattgc tctagcgctt cacgaccatt aaaagcagtt acaacttcgt aaccttcctt
     2821 ggtcatatta aacttgataa tatccgagat tggtttctca tcatctacaa ttagtatttt
     2881 tttcatatgt tcaccttttt ctccactatt ataccaaaaa aatagtcaga agacacaata
     2941 gctagtcttg gctactgtct aagttggctt gtgcataagc ctgccagatt ttttgttggg
     3001 gtttggcaag tgggtaattc ttgaattctt ctggtgaaag ccagcgaact tccctatctg
     3061 aaaaatcatg gaagtcactc acctgacctg ctacaatctg cacatgccat tttcgatgac
     3121 taaaaacatg ctggactgta tcaaaacaaa catcaagcca atcaacatct aggtcatagt
     3181 cctgctggaa actctcttct ggactgggac caaagttcac actttcttcc gcaacctgat
     3241 gaaagaggtc aaactgctct tcttgcgaaa agttatcaac ttctataaag gggaaatgcc
     3301 aaaaacctgc caagagcttt tcgctttcat ttttttcaag taaaaattgt ccttgagaat
     3361 ttttcacaac taaggcttta agataaatag gaaccggctt tttcttagga gatttaattg
     3421 gataacggtc catggttcca ttctgatatg ccgcactaaa gtccttgact gggctttctt
     3481 caggtctggg atttacagga gactcaatat cagaccctaa gtccatcaag gcttgattaa
     3541 aatcacctgg acgatccgga ttaatcaaga tctccatcat tgcctgaaaa atttttcgat
     3601 tacttggaat cccaatatcg tggttgactt caaacagacg cgccaagacc cgcatgacat
     3661 taccatctac agctggctca ggcaagttaa aagcaatact ggaaatggct cctgctgtgt
     3721 aaggtccaat ccctttcaag ctggaaattc cttcataggt atttggaaat tggccaccaa
     3781 agtcagtcat aatctgctgg gctgcagcct gcatattgcg aactcgagaa taatagccca
     3841 agccctccca agctttcagt aaactctcct cagacgcagt tgccagactt tcgacagttg
     3901 gaaaccagtc caggaatctt tcgtagtaag ggataactgt atccaccctg gtctgctgaa
     3961 gcatgatttc agatacccag atgtgataag gatttttact tctcctccaa ggcaaatctc
     4021 ttttgttttc atcataccaa gcgagaagtt tctcacggaa agaaatgact ttctcctccg
     4081 gccacatgac gataccgtat tctttcaaat ctaacatatc tctagtataa cacagaaggt
     4141 ttcacctgtc tttgtatctg atttataata ttttcaatag atagtatata acttttctat
     4201 ctacttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa
     4261 acactgtttt gaggttgtgg atagaactga cagagtcagt atcatatacc tacggcaagg
     4321 tgaagctgac gtagtttgaa gagattttcg aagagtataa atcttattga tgaactgctt
     4381 gcagtctgag aaaaaatgag cttggatatt atttccaaac tcacttaaag tcaatttcaa
     4441 tccactagaa caagcctagt acagttccat cgctttcaac atccatgttg agagctgctg
     4501 gacgttttgg aagacctggc atggtcataa catcaccagt taaggcaacg atgaagcctg
     4561 cacctaattt tggtaccaat tcacgaatgg taatttcaaa gttttctggt gctccaagcg
     4621 catttggatt gtctgagaaa ctgtattgag ttttagccat acagattggc aatttgtccc
     4681 aaccgttttg aacgacttga gcaatttgtg tttgagcttt cttctcaaag ttcactttgc
     4741 taccacgata gatttcagtg acaatttttt caatcttttc ttggacagaa aggtcattat
     4801 catacaaacg tttatagtta gctggatttt cagcaattgt cttaacaact gtttcggcaa
     4861 gttctactcc accttctact ccatcagccc agacactagc caattcaact ggtacatcga
     4921 ttaaggcaca gagttctttt aaggctgcaa tttcagcttc tgtatcagat acaaattcgt
     4981 taatagctac aactgctgga ataccgaact tacggatatt ttcaacgtgg cgtttcaagt
     5041 tagcaaaacc tgcacgaact gcctctacat tttcttcagt cagagcatct ttagccacac
     5101 caccattcat cttaagggca cgaagggttg cgacaataac aactgcatct ggagatgttg
     5161 gcaagtttgg tgtcttgata tcaaggaatt tctcagcacc aaggtccgca ccaaaaccag
     5221 cttcagtaac agtgtaatca gccaagtgaa gggctgttgt cgtcgccaaa acagagttac
     5281 agccatgagc gatattggca aatggaccac cgtgtacaaa ggcaggtgta ccgtaaattg
     5341 tctgaaccaa gtttggctta atagcatcct tcaaaatcaa agccaaggca ccctcaacct
     5401 gcaaatcacc tacagaaaca ggcgtacggt catagcgata accaataacg atattcgcca
     5461 aacgacgttt caagtcctcg atgtccgttg ccaagcaaag aattgccatg atttctgaag
     5521 caactgtaat atcaaaacca tcctcacgtg gaataccgtt tagaggacca ccaagaccaa
     5581 cagtcacatg gcggagcgca cggtcgttca agtccacaac gcgtttccag aggatacgac
     5641 gttgatcaat tcccagctca ttcccttggt gcaagtggtt gtcaatcaag gcagaaaggg
     5701 cattgttggc agttgtaata gcatgcatat ctccagtaaa gtggaggttg atgtcttcca
     5761 ttggcagaac ttgtgcatac ccaccaccag cagcaccacc cttgatcccc atgactggac
     5821 caagagacgg ttcgcggata gcaatcatgg ttttcttgcc aatcttgttc aaggcatccg
     5881 caagaccaat ggtaagcgta gactttcctt cacctgcagg tgttgggttg atggcagtaa
     5941 ccaagatcaa tttaccgact ggattgctct caactgcccg aattttatca aagctgagtt
     6001 tagccttgta ctttccgtac aactccaaat cgtcgtaaga aataccaagt ttctctacaa
     6061 catcaacaat tggcttcaac tcaatactct gtgcgatttc aatatctgtt ttcattcaaa
     6121 attcctctaa cctcttatat gataattcat tatatcacaa aacaagattt ttaacatcct
     6181 aaaactctct aaacgttcgt aaatatctct gtttttaagg cttttagagt cctttcttaa
     6241 attttatatg gctttatagt ttgaaactat aataaatctt cgtttttacc aaaaatttat
     6301 cactttcatt ttacttaccg cttatttttg tgtacaatag tgctatgaaa attttagtta
     6361 catcgggcgg taccagtgaa gctatcgata gcgtccgctc tatcactaac cattctacag
     6421 gtcacttggg gaaaattatc acagagactt tgctttctgc agggcatgaa gtttgtttaa
     6481 ttacgacaaa acgagctctg aagccagagc ctcatcctaa cctaagtatt cgagaaatta
     6541 ccaataccaa ggaccttcta atagaaatgc aagaacgtgt tcaggattat caggtcttga
     6601 tccactcaat ggctgtttct gactacactc ctgtttatat gacagggctt gaggaagttc
     6661 aggctagctc caatctaaaa gaatttttaa gcaagcagaa tcatcaggcc aagatttctt
     6721 caactgatga ggttcaggtt ttgttcctta aaaagacacc caaaatcata tccctagtca
     6781 aggaatggaa tcctactatt catctgattg gtttcaaact gctggttgat gttaccgaag
     6841 atcatctggt tgacattgca cgaaaaagtc ttatcaagaa tcaagcagat ttaatcatcg
     6901 cgaatgacct gactcaaatt tcagcagatc agcaccgagc tatatttgtt gagaaaaatc
     6961 agcttcaaac agtccagact aaagaagaaa ttgcagaact cctccttgaa aaaattcaag
     7021 cctatcattc ttagaaagga aaactatggc aaacattctc ttggctgtaa cgggttcaat
     7081 cgcctcttat aagtcggcag atttagtcag ttctctaaaa aaacaaggcc atcaagtcac
     7141 tgtcttaatg actcaggctg ctacagagtt tatccaacct ttgacactac aggtactctc
     7201 acagaatcct gtccacttgg atgtcatgaa ggaaccctat cctgatcagg tcaatcatat
     7261 cgaacttgga aaaaaagcag atttatttat cgtggtacct gcaactgcta acactattgc
     7321 aaaactagct cacggatttg cggacaacat ggtaaccagt acagctctag ccctaccaag
     7381 tcatattccc aaactaatag ctcctgctat gaatacaaaa atgtatgacc atccagtaac
     7441 tcagaataat ctgaaaacat tagaaaccta cggctatcag ctgattgctc ctaaggaatc
     7501 cctactagct tgtggagacc acggacgagg agctttagct gacctcacaa ttattttaga
     7561 aagaataaag gaaactatcg atgaaaaaac gctctaatat tgcacccatt gctatctttt
     7621 ttgctaccat gctcgtgata cactttctga gctcacttat ctttaacctt tttccatttc
     7681 caatcaaacc gaccattgtt catattcctg tcattattgc cagcattatt tatggtccac
     7741 gagttggggt tacacttgga tttttgatgg gattacttag cttgacggtt aacacgatta
     7801 cgattctacc gacaagctac ctcttctctc ccttcgtacc aaacggaaac atctactcag
     7861 ctatcattgc catcgtccca cgtattttga ttggtttaac tccttactta gtctataaac
     7921 tgatgaaaaa caagactggt ctgattttag ctggagccct tggttccttg acaaatacta
     7981 tctttgtcct tggaggaatc ttcttcctat ttggaaatgt ttataatgga aatatccaac
     8041 ttcttctggc aaccgttatc tcaacaaatt caattgctga attggtcatt tctgcaattc
     8101 taaccctagc cattgttcca cgactacaaa ccttgaaaaa ataaaaacaa tctccgcttt
     8161 caaacctgaa ggtggagatt ttgctctata cagtttcttt ttaatgaaat ctttactata
     8221 gtaaaacgaa ataagaacag gataaatcga tcaggacagc caaatcgatt tctaacaatg
     8281 ttttagaagt agaggtggac tattctagtt tcaatctact ataactttta actaaaaaat
     8341 tatctataaa cccaagtaaa ttcttgcttt attgtctggt ttattgtacc atactagtgt
     8401 atatgcagtt aaaaaggaga ttcttgtgaa tacacggaaa aagacacaat ttatgacaat
     8461 gacagccctt ttaacggcta ttgcgatttt gattccaatt gttatgcctt tcaagattgt
     8521 cattccacct gcttcctata ctttggggag ccacatcgct atttttatag ccatgttctt
     8581 gtcgcccttg atggcagttt ttgtcatcct agcctctagt tttggatttt tgatggctgg
     8641 ctatcccatg gttatcgttt ttcgggcttt ttcccatata tcttttggtg ctttaggagc
     8701 tctttaccta caaaaattcc ccgataccct agataaacca aaatcttcct gggttttcaa
     8761 ctttgttttg gctgttgttc atgcccttgc tgaagtatta gcctgtgtcc ttttttacgc
     8821 aacttcgggt accaatgtag aaaacatgtt ctatgttcta tttgtgctag ttggatttgg
     8881 cacaattatc catagtatgg tagactatac attagcacta gctgtctata aagtgcttcg
     8941 aaaacgccgt taaaaggaaa agctatgaca aaagatcgca aacaagccct gctccaactc
     9001 ttgaaagaag ctcctaaagc ccttaatggc caaagtttgg cggaacattt tcatgtcaca
     9061 cgtcaggtca ttgtgcagga cattgcaatt ttgagagccg atggcgctcc tatcctatcc
     9121 accaatcgtg gctacatcta taagcaaatt gataccaatc cttatgttca caaacttttc
     9181 aaagtgaaac atgaagttga agaaatcggt caggaactcc ttgctattgt cgataatggt
     9241 gggcatgtcc agaatacctt gattgaccat cccgtttatg gagaaattga aaccttgctt
     9301 aaactgtctt gtcgcagaga tgtgcaacat tttctagaac aagtcgagca ttctgacttt
     9361 agacctctat ctgaattgac agatggcatc cattaccacc tagtcgaagc cgaaacacaa
     9421 caagacctcc actatatcga ggaggccttg gatcagctag gttatttagt aaaagactag
     9481 aagattttct tttcccaatc gtcttctgta cggcgagggt agaaaaattc agacttatca
     9541 ggagcttcca tcatctccat caagggtagc atatcatagg ccagatccaa gtttggaatc
     9601 tggtcttttt gcacccaaga aacttctccc tcttctgaag attgaagagt tccagtaaac
     9661 tcagttgcct tataacaaat gacaatatag cgcccacctg tatccagtgg ccaattttta
     9721 atgccgacaa gttgaggatt ttggatagtc aaccctgttt cttcatagat ttcacgaatg
     9781 acagactctg cgaaagactc gccattttct acatggcctc ctggaaaggc ataaccagac
     9841 cagcgattgt tttcaggagc gcgatactgc atcaccacgc gctgagtttc gaggtcttca
     9901 atcagacaaa tgtttgttaa aatcgttaat tgtgaacggg acataaattt actcgctttc
     9961 taatttatta aattttcaga cttggtacca gagatattag cttttacttt ttaaaattat
    10021 ttagaataga ataccatccg tttttccttt ataggctttc caagttcaag tatcttttct
    10081 tgtccatcaa aagtaaaacc cattttttga tagaaagcaa tggcgcgctt attatctttc
    10141 aatacccata agaaaatttc agaaaaatga ttaagagcag tcaaagctac tttcactaac
    10201 ttttgtgcga ttccttttcc ataatagtct tttaaaacat ataaagcaat aatttcacca
    10261 gcttgaatag tctcatcacg aaagctgcca taactgataa aaccaactac cttcaggtca
    10321 tctatcgcaa tcaatgtatt ttctggatac ttttgactaa agaatcgaca tctttctaat
    10381 gtcattgttt cctgaaattc tgcaggcaaa aggtcatcat aagcctctct ccacgtttgc
    10441 cagtgaacaa gggatttacc ttctatctct tcaggagttt ccattgattt gataataacc
    10501 gtcatttatt ttctcccagt cttctctcaa aataccatat ttaatactat caaaatattt
    10561 accttgataa taacgaactt ttggaatatg agcttctttt ttcattctta atttttcagc
    10621 aagtttcatc ataccaagat tccctgacca agttgtcaaa cccagatgct ccaactccaa
    10681 gtaatcctga aacgtcctat ctatccactg caacatagca actttcccaa taccagtgtt
    10741 ccagaatttt ttatcataaa taccaattcc caattccatc catcttgttt gtttacatac
    10801 ccaataacgc gaaacagtcc caactagttt atcatcaaca aaaataccaa ggcgatttga
    10861 gttgcttaaa atggattctg atttttgtag ttcgaattct ttaaaatttg aaaaatactg
    10921 ataatcatca taatagggag catcatactg tttccaaact ggattaagtt gtgaataagc
    10981 catttcccat aaagacatca aatcttctct ctttaacttt cttaaataaa tcatactatt
    11041 cccctaatcc aagaccttga cttccaacat catatcacga atctgagccg ccagttcaaa
    11101 gtcaagcact tcgacggctt cttgcatttg tttttctagt ttcttgacga gttccttgcg
    11161 ctcttgtttg ttgaggctat tgatgtcgac ttccttgtcc tcttccttag caactgcctt
    11221 ggtcacggca atcaggtcac ggatttcttt cttgattgtc tgtggtacga tatcatgctc
    11281 ttcattatag gtcatctgaa ttttccgacg gcgggcagtt tcatcgatag cacgttgcat
    11341 agactgggta accgtgtctg catacatgat gacatggcct tcactgttac gagcagcacg
    11401 tccaatagtc tggatgagtc cacgttcgtt gcgaaggaaa ccttccttat cagcatcgag
    11461 aatagctacg aggctcactt caggaacgtc aattccttca cggagcaggt taattccgac
    11521 caagacatca aagacaccca agcgcaggtc acggataatc tccgtccgtt ccaaggtctt
    11581 gatatccgag tgcatgtact tgaccttgat acccatttcc ttgaagtagt cggtcaagtc
    11641 ctctgccatt ttcttggtca aagttgtgat aaaggtacgc tcattttttt caacgcgggc
    11701 attgatttca cccaagaggt catcaatctg tcccatagtc ggacggactt ccacttcagg
    11761 atccaagagt cccgttggac gaatgatttg ctcaatcact gtctcagtct gttcattttc
    11821 atagtcacca ggtgtcgctg aaacgtaaac aatctgatga acgtgactct caaactcctc
    11881 ccgacggaga ggacgattgt ccaaagcaga cggcaatcgg aagccataat taaccagcat
    11941 ttctttacgc gaacggtctc cattgtacat gcccttgatt tgccccatgg tcatgtgact
    12001 ctcgtcaatc ataattaaga aatcatctgg gaagaaatct aagagcgtat aaggaggctc
    12061 tccttcgctc cgtccatcca tgtgtcgtga atagttctca accccattgg tatagcccat
    12121 ctcacgcaac atttcgatat catactctgt ccgctgtttc aaacgctggg cttcaagcag
    12181 tttaccttcc ttttcaaaga cagctaattg ttcttccaac tcggcctgaa tctttgcaat
    12241 ggcaacttcc atgtggtcgt cattggtcac aaagtgtgtc gctgggaaaa tcgctaaatg
    12301 atccacttct cccaacacct gacctgtcag agcctcaact tcacgaatac ggtcaatttc
    12361 gtctccaaaa aattctactc gaaaggcatg ttcatctcgg gaagctggga aaatctctac
    12421 cacatcccca cgaacgcgaa atcttccgcg ttggaaatca atatcattac gttcaaactg
    12481 aatatcgacc aagtcattca agagtttatc acgagaaatc tctagaccag gacggagact
    12541 aacgacacta tcagcgtatt ccttgggcga acccaaacca tagatacaag agactgaggc
    12601 cacgacaata acatcattac gctccaaaag ggctgaggta gctgagtggc gaagcttgtc
    12661 aatctcgtca ttgacagaac tatccttctc aatataggta tcgctagaag ggacataggc
    12721 ctctggctgg taataatcat agtaggatac gaaatactca actgcatttt cagggaaaaa
    12781 ttccttaaac tccccataga gctgaccagc cagagtttta ttgtgggcaa taaccagagt
    12841 tggtttattg actttagaaa tgacctgact catagtatag gtcttccctg ttccagtcgc
    12901 ccccatcaga atctgagctt tttctccccc ctcaatgtta tccaccaact gctcgatagc
    12961 ttggggttga tctcctgatg gttgatattt tgatactagt ttaaattgat tatctgtaat
    13021 gtgattgatc ataagaatcc tctctccatg tgctattcct attttagcat acttatagta
    13081 ttttcacgaa gaaaaggacg gaccgaagtc acatcctttc attttctttc tttaatttat
    13141 tagcaagata gacaatcagc agtagtaata ccagacttgt cataatggaa ccttctatgc
    13201 caaaagaacc acctgatagc caatcttgat tgccttgtgg taaaaaggtc atcagagacg
    13261 ttcctgacgg ttgaccacta actaaaatcc caaagagatt accctgagca aaattccaag
    13321 caccatgaat acctgcaaca ccccaaactg tatcagtttt gagaaggtaa agagccatgg
    13381 caactccgaa taaaaagaga tttactagag atagaggggt gagaccagaa ttgcccatat
    13441 gaagcagggt aaagaacagg ctagatataa gaatagctag ttttagattg gttcttgagg
    13501 ccaattgagg aagtagccaa gcacgggcca ccacttcttc tgctgtcccc tgtaaaatcc
    13561 aaaatgggat agtaaagacg acaaaggcaa gagaataagg attcaagtga atggattcca
    13621 aacgatattg acctaagacc accaaaccta acaaggtcag aagaaaaagt gccagaccta
    13681 gactaaatcc tttcagaaga ttgctgagga aattctctct ataaaatccc aaggttcgaa
    13741 taggtctttt ctcaactttt cttgtccatc tgaacacagt gttaagaata aaaccaaagg
    13801 ccagtaatcc taaaattaaa cgaaagtcac ttgttttatc cgtcaagctc tgatgcaagg
    13861 tctgcaagta gcttgcaaga ttttgaccag cctctccaaa atttctagca agtccgatga
    13921 gagctaacaa actaatacca tataaagtat aagccacaaa ctctcctatg aagacaaaaa
    13981 caaaggctaa caaggggctt gtgtaaatgt ttaaattcat ttttgaagct tggaagtctt
    14041 taaatattct tttgttcttc atatccccgt cctctttt
//
LOCUS       DAVLIK010000045        14044 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLIK010000045 DAVLIK010000000
VERSION     DAVLIK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.045"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(105..542)
                     /locus_tag="VXE87_001638"
     CDS             complement(105..542)
                     /locus_tag="VXE87_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0843159.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(627..3260)
                     /gene="polA"
                     /locus_tag="VXE87_001639"
     CDS             complement(627..3260)
                     /gene="polA"
                     /locus_tag="VXE87_001639"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0843160.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPVLLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3516..3866
                     /locus_tag="VXE87_001640"
     CDS             3516..3866
                     /locus_tag="VXE87_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0843161.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4081..4197
                     /locus_tag="VXE87_001641"
     CDS             4081..4197
                     /locus_tag="VXE87_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0843162.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4190..4423
                     /locus_tag="VXE87_001642"
     CDS             4190..4423
                     /locus_tag="VXE87_001642"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843163.1"
                     /translation="MFNQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFTFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            4550..4831
                     /locus_tag="VXE87_001643"
                     /pseudo
     CDS             4550..4831
                     /locus_tag="VXE87_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4965..5933)
                     /locus_tag="VXE87_001644"
     CDS             complement(4965..5933)
                     /locus_tag="VXE87_001644"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0843164.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(6078..6893)
                     /locus_tag="VXE87_001645"
     CDS             complement(6078..6893)
                     /locus_tag="VXE87_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV0843165.1"
                     /translation="MKKSSILFIFILLLCIDLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(6918..7415)
                     /locus_tag="VXE87_001646"
     CDS             complement(6918..7415)
                     /locus_tag="VXE87_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0843166.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(7488..8849)
                     /gene="radA"
                     /locus_tag="VXE87_001647"
     CDS             complement(7488..8849)
                     /gene="radA"
                     /locus_tag="VXE87_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0843167.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSTNVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(8863..9378)
                     /locus_tag="VXE87_001648"
     CDS             complement(8863..9378)
                     /locus_tag="VXE87_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0843168.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(9380..9823)
                     /locus_tag="VXE87_001649"
     CDS             complement(9380..9823)
                     /locus_tag="VXE87_001649"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0843169.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(9880..9977)
                     /gene="ffs"
                     /locus_tag="VXE87_001650"
     ncRNA           complement(9880..9977)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXE87_001650"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(10010..10477)
                     /locus_tag="VXE87_001651"
     CDS             complement(10010..10477)
                     /locus_tag="VXE87_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0843170.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(10678..11964)
                     /locus_tag="VXE87_001652"
     CDS             complement(10678..11964)
                     /locus_tag="VXE87_001652"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0843171.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(12195..12431)
                     /locus_tag="VXE87_001653"
     CDS             complement(12195..12431)
                     /locus_tag="VXE87_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0843172.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            12697..13558
                     /locus_tag="VXE87_001654"
                     /pseudo
     CDS             12697..13558
                     /locus_tag="VXE87_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13593..13802)
                     /locus_tag="VXE87_001655"
                     /pseudo
     CDS             complement(13593..13802)
                     /locus_tag="VXE87_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13968..14041)
                     /locus_tag="VXE87_001656"
     tRNA            complement(13968..14041)
                     /locus_tag="VXE87_001656"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14005..14007),aa:Asn,seq:gtt)
BASE COUNT         4445 a         3346 c         2355 g         3898 t
ORIGIN      
        1 caacctcaaa acagtgtttt gagcagcccg cggctagttt cctagtttgc tctttgattt
       61 tcattgagta taacacaaaa ggtagcccat cagctacctt tttcttatgc ttcctcaatc
      121 aagcgagtat gttctctctt gatacagcga ttcatcacga tatcatcaca tccaccatca
      181 cgcaaaatct ctttcgcttc taaactttca agtcctagct gtgcccaaaa aatcttggca
      241 tcagctttga gaaaatcacg cgccacatcg ggcagaaatt cactgcgacg ataaacattg
      301 acaatatcta caggaaaagg aatttcagcg aggctagcat aagccttttc acccaagatt
      361 tcgccacctg ccgccttggg attgactggg atgattttat agccccgagc ctgcatttcc
      421 tttgtcactc gattgctggt tgtttcttca cggtcagaca aacccaccac agcaagggtt
      481 ttactcgttg cgagatactg acgaatcacg ccatcacttg gattgataaa ttcttgactc
      541 atagaaaacc tcctttttca tcagtatagc acattttgaa aaggtttgca gaattctact
      601 acaaaaaagg aggactagcc ccctttttat ttagcctcgt accaggttgc cccttcattc
      661 tcatctgcga taagaggaac actgagttga atggcttctt ccatggtttg tttcaccaat
      721 tttttcatct ctaccaattc agatttaggc acttcaagga cgatttcatc gtgcacttgt
      781 aacagcatct tagtctgata accacctgca accaaggctt tatccagctg aatcatggca
      841 atcttgagaa tatctgctgc cgaaccctgg ataggtgagt tgatagcagt tcgctccgca
      901 aaaccacgaa tattgaagtt gcgcgaattg atatctggca actcacggcg acgcttaaag
      961 agggtctcta catagccctt atcacgcgcc tcccgcacca cttcatccat gtagttttta
     1021 atacctggaa aacgttcaaa gtaggtatca atgtaggctt tggcttcctt acgactaatt
     1081 cccaaattat tagacaagcc aaagtctgaa atcccataaa ccactccaaa gttaactgcc
     1141 ttggcattgc gacggtcatt tgcagtcaca ttatcaggac gctcaatgcc aaagacccgc
     1201 atggctgtcg aagtatggat atctgccccc tcttggaagg ccttaatcaa gtgctcatcc
     1261 ttagaaatat gcgccaaaac gcgcaattca atctgtgaat agtcagagct gagtagcaca
     1321 ctatcctccc actctggcac aaaagccttc cgaatcaagc gcccctgttc caatcgggca
     1381 ggaatatttt gcaagtttgg atccacacta gacaaacgcc cggtctgggt caaatcctgc
     1441 acatagcgag tatgaatctt tccatcagcc aaaatccagt cctgcaagcc aattacataa
     1501 gtagattgaa tcttagcaat ttgacggtaa tccaggattt tcttaacaat cggagcaata
     1561 ggagcgagac gctccaacac atccactgct gtcgaataac ctgtcttggt tttcttagtg
     1621 tattctagag gaagtcccaa tttctcaaag agaagcacgc ccaactgctt aggcgagttg
     1681 acattaaact cctcaccagc cagctcgtaa atctcttgag tcagtttttc aatgacaagc
     1741 tcattttcag cctgcatctc aagcaaggtc tctttcttga ccacaatccc agcaatttcc
     1801 atcttggcaa gaacaaaagc cagaggttgc tccatatcat aaagaagctc taattgccca
     1861 ttttcgctga gtttttcaag tagaacaggc tctgtttcta ccaaaacagc aagtttacaa
     1921 gctaagtgtt ccaagaattt ctcacgttca ggaatggcct ttttaacacc cttaccgtag
     1981 aaagtttcat catcaaccaa gtaagtctga ccataaagac tagcgatggt cgcaatttca
     2041 ttgtcctcca cagtcgaaag gaggtattta gccaaacgga tgtcaaaagc aggcgcctgc
     2101 aaatccacac caaaacgttg caaaagaact ttaaccttct taaagtcata aactctcaga
     2161 gatgtttttt ctaagaaatc cttgaaaatc gggtcttgca acagctcaag cttgtctgtg
     2221 gcatagagct tatccccaca agaccaggca aatccaacca aattatccgt atggtaattc
     2281 tcaccaaaaa gctcaaagtg gaagatagac tcttcactca gcatatcttg actgatttgg
     2341 tcaacaatag taaaatccaa accctcagcc acatcagctg acgacacatt taaagcctgc
     2401 ttgagctgtt tgaatcccat ctcatcgtaa aatttcccaa gattttcaac atctggacca
     2461 ctatagacca agtcctctaa accaatcgca atcggtgcct tggtatcaat ggtcgctagt
     2521 gttttagaca aaaaggcctg ttccttgtca ttgatgagat tttccttcat cttagaagtc
     2581 ttcattccat caatattttc ataaatcccc tcaagcgaac catgctccag caagagctta
     2641 atacccgtct tttcaccgac tttggtcacc ccagggatat tatccgactt atcacccatg
     2701 agcgccttga gatcgataaa ctgagctggt gtgaggccca tttcttccat gaggtaatct
     2761 ggcgtaaagg cctcaaactc agccacacct ttcttggaaa tttcaaccac cgtatgctca
     2821 tccgtcagct gaatcaaatc cttgtcccca ctgacaatgg taatatcaaa accatcctgc
     2881 tctgctagct tatccagcgt cccaatgatg tcatccgcct catactgagc cagctcatag
     2941 tgacgaatcc ccatatgatc cagcaactca cgaatgaaag gaaattgctc acgaaactca
     3001 tcaggagtct tggcccgacc acccttatag tccgcataca tctctgtccg gaaggtcgtc
     3061 tttcccgcat caaaagccac caaaatatga ctcggctcaa cccgctccaa caaatgactc
     3121 aacatcaact gaaaaccata aatcgcattg gtatgcaaac cagccgcatt cttaaaacgg
     3181 tccaactgct gatacagcgc aaaaaacgcc cgaaaagcta cagaagaccc atcaatcaat
     3241 aataattttt tcttatccat acacccatta taaaggaaag aatcaaaaaa taccattggg
     3301 aagagctaga gctagtattt ttcaaacttt ttccgaataa atagatagag ccagagaatt
     3361 tagtaaacct agatttaaaa atgtgctata atatagtata ttgaatctat aatagtacac
     3421 cttgactgct aaaatatttc tataaattaa tttgactttc ctgatagagt tattcacatc
     3481 ttatttcaac tcactataga aggaggaata ggaggattct cagacatccg ggcatcagcc
     3541 caactaatga tttgattgct aagaaaatat tcagcaatcc agaaatcact tgtcaattta
     3601 ttcgcgatat gctggacttg ccagcaaaaa atgtgaccat tttggaggga agcgatattc
     3661 acgtattact ctccatgcct tactcggtgc aggattttta taccagtata gacgtcttgg
     3721 cggagttgga taacggtact caagtaatta ttgagattca agtccatcat cagaattttt
     3781 tcatcaatca cttgtgggct tacctgtgca gtcaggttaa tcaaaatctt gaaaaaattc
     3841 gtcagcgaga aggtgatact cactagagct acaaacacat cgctcctgtt tacgccattg
     3901 ctatcgtgga tagtaattat ttctcagatg acctggcttt tcatagcttt agtatgcgcg
     3961 aagacacaac aggtgaggta ttggcgatta ccaacaatgg acaggaaaac catctggtta
     4021 agatggcatt cttggaatta aaaaatacag agaaaccagc aaagacaagg ttcgcaagcc
     4081 atggttggag tttttcggca acaagccctt tacccagcaa ccgcaacgag ccattaccca
     4141 agcaaatcaa ctgctggact acaagagctg gtccgaggag gacaggaaaa tgtttaatca
     4201 actacatatg cgagaagaac aagtcttgtt agcacaggac tatgccttgg aaactgctag
     4261 ggctgaaggc cttgaacaag gattagagcg tgggaaagtt gaaggaaggg cagaaaggaa
     4321 actttttacc ttcctagaca tagtacgcca aggtcttctg acttctgagg ttgccagcca
     4381 gcaattaggt atgtcagtat ctgaatttga ggcactgttg taaaatggct ccataatatc
     4441 catagtgggt aaatccccta tggatattat ggagcctatt ttgtgtagaa aaaaagtccc
     4501 atatgaccta taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt
     4561 acattttatc acaaaattac tagacattaa agaccctaat gtccagattt taaacatcat
     4621 caataaggat acacacaagg aaatcatcgc caaactggac tacgacgccc catcttgccc
     4681 tgagtgcgga aaccaattga agaaatatga ctttcaaaaa ccttctaaaa ttccttatct
     4741 tgaaacgact ggtataccta ctagaattct ccttagaaag cgtcgattca agtgctatca
     4801 ctgttcaaaa atgatggtcg ctgaaacttc tgatgacgta cagtcatatt tcttttcttt
     4861 ttattatatc acagttttaa atctagcttt actagattca ccgctactat ctatttattc
     4921 ggaaaaaaga cgaaaaaacc tgagaatcat ctcaggcttg gtcattaaat ttttttctca
     4981 atatcgaaaa gtggagaaag tggtcgtttt tcatgaatac gtacgatagc atcccctagg
     5041 agatgagcga ttgaaatctg ctcaatctta tcaatcaaac gctcttctgg cagatagatg
     5101 gtatccaaaa caaccaattt cttaatagct gatttttgga tattgtccgt agcaggacca
     5161 gaaagaactg ggtgcgtaca gcttgcatag acttcaacag caccagcttc cgcaagagca
     5221 tctgccgcat gacaaatcgt tccagcggta tcaatcatat catcaatcaa gatacaagtc
     5281 ttgccttcaa ccttaccgat gatgttcata acttcactag tattcatctt atcaacgctg
     5341 cgacgtttat caataatagc gatagatgtt ttcaaaaatt ctgccaactt acgagcacga
     5401 gtcacccctc catggtccgg gctgacaacc acatagtcag aaccaaccat accacgacgc
     5461 tcaaaataat ctgcaatcag aggagcaccc atcaaatgat ccacaggaat atcaaagaat
     5521 ccttgaattt gcgcagcatg caagtcgatg gtcaataaac gatccactcc agctacttca
     5581 agcatatttg cgacaagttt tgaagtgatt ggctcacgcg ctctcgcctt tctatcctga
     5641 cgtgcatacc catagtaagg catgacaaca ttgacagatt ctgcactcgc acgcttcaaa
     5701 gcatctacca taatcaaaat ttcaagcaga ttgtcattta caggcgaact agttgattgt
     5761 aggataaaga cgtgtttccc acggattgat tcttcaatgt tgacctgaat ctctccatct
     5821 gaaaattggc gaacacttga tttccccaac tctatcccaa tctcctgcgc tacacgttct
     5881 gccaattctt tattagaaga aagggcaaac agctttaaat cagaaaaaga catgatttcc
     5941 tccggtatat atgtataact tgtgcttttc acaagatttt ccatctacca ttgtagcgct
     6001 ttttgcacta tttttcaatc aaaaataaaa gaagggcacc atatttgtac ccttgcatca
     6061 ttcttttgaa aaatattcta ggtcatcaac tcattgtgtt tctcaacaaa gcaataagca
     6121 tgataaaaac catagagagc aatagccgta accactggaa tcgctaaagg caactctgtt
     6181 tccaactcca caaaaggaga gttaaacaag aagtgagttc ccaaggctaa acctagaaaa
     6241 ataaggccct gtttcttgcc aaccttctgt cctttatagg ctctgtaaag caagtaaaca
     6301 cctactacag ctagacctga aaaagtccag tgagaggcaa ttcctgagat gatacgctct
     6361 aaaattcgcg aaatagtaaa gtcaaagccc tctggcaaat ccgtacgaat ataaccaata
     6421 tcctcaatca tttggaatcc caaaccggaa gcaattccaa gtaaaaacaa agattttaat
     6481 tttcgcacag gaatcaaagc caaaacaaaa acaagtggca ataatttcaa gggttcttct
     6541 accaaaggag ccacaatagc actttcaaag gcatttaaaa atggactatc tgggaaaaga
     6601 acccccagta aatcatgtat ataagtatta gcaaaactag acaaccagcc tgaaaggaac
     6661 atccctccca ataaagacag aatcaaaacc ttctttggca attcccattt tttcccaata
     6721 cggaagagaa aataaagagc cggaatcatg taaaagagag ctagaaagat agaaactccc
     6781 attagtccat attccgcacc tgacctcgaa ccgtccgtat agtagatggt ttcatactgt
     6841 aaatcaatac atagcaataa aataaaaata aataaaatac tgcttttctt catacacttt
     6901 ctttctaaat gaagtattta taattctacg actgtcatac ttcctgtatc aacattgtaa
     6961 atagcaccag agataatgac atcgtctggt attaggggag actcgataag cagttgcata
     7021 tcctcgcgta cactctcttc tatatcttgg aagggcaaga agtcctggtc tgacacatct
     7081 acacctaatt cctcttttaa atactcctga aaaggttcat tttcaaaggt ctgagcacca
     7141 cagtctgtat ggtgcaatac cacaatctct cttgtcccca tttgttgctg ggaaataact
     7201 agcgaacgaa tcatgtcttc agtcactcga ccacctgcat tccgcaagat atgagcatcc
     7261 ccaagtgcca agcccagagc ttgcgcaacg tgcagacgag agtccataca ggtcacaata
     7321 gctactcttg ttttgggttt aagtggcaga tttaactgcc catgtagggc aacataagcc
     7381 tgattagctt gcataaactg ttcaaaatac gacacgattc cctccttgaa aatttgatag
     7441 tcaaatattt ctcctatctt atcattttta agagaatttg tcacggatta tgcaaagacc
     7501 tttttcaaaa cttcctgaat cgttgtcacg ccaatgacct gaatttcctt aggcagagtg
     7561 attcctgtca aggaattctt aggtacataa atcttagtaa agcccagttt agcagcttcg
     7621 ttgatgcgtt gctcaatacg attcacgcgc cgaatctctc ctgtcaagcc cagttctccg
     7681 acaaaacatt cctgaggatt agttggcttg tctttgtagc tcgaagcaat agcaactgca
     7741 acagccaagt caatcgcagg ttcatccaat ttaacaccac cagcagattt gagataggca
     7801 tcctgatttt gcaagagaag ccctgcccgt ttttccaaaa cagccataat caagctagca
     7861 cggttaaaat caagtcctgt cgtagtacgc ttggcatttc caaacatggt cggtgttacc
     7921 aaagcctgaa cctccgccaa aatcggacgc gtcccttcca tggttacaac gatggaggaa
     7981 ccagtcgccc catccaaacg ctcttctagg aaaacttgac tcggattgag tacctcaacc
     8041 aagccgcccg actgcatctc aaaaatccca atctcattag tggaaccaaa acgatttttg
     8101 accgctctca aaatacgaaa ggtgtggtga cgctcccctt caaagtaaag caccgtatcc
     8161 accatatgct ccaacatacg aggcccagcc aaggttcctt ctttggtcac atgacctacg
     8221 ataaagatgg caatgttatt ggtcttggcc aactgcatga gttcagcggt cacttcacgc
     8281 acctgagaaa cagacccctg cacccctgaa atctcaggag acatgatggt ctggatggaa
     8341 tcaataatga gaaagtctgg ctggatacgc tccacttctg cacgaacact ctgcatattg
     8401 gtctctgcat agagataaaa ctcactatca atatcaccta agcgctctgc acgtagttta
     8461 atctgctggg cagactcctc cccactgaca tagagaactg tccccacttg ggacaactgg
     8521 gttgagactt gtaggagaag agttgatttc ccaatcccag gatccccacc gataaggacg
     8581 agacttcctg gtaccactcc gcctccaagc acacggttga attcctccat ctccgtcttg
     8641 gttcgattga cattggtgga agtcacctca gctagtttca tgggcttggt tttctcacct
     8701 gtcaaggaca cacgcgcatt cttaacttcg gcaacctcaa cctcttccac aaaagaagac
     8761 caagacccac agttggggca acgtcccaga tatttagggg aattataccc acaattttga
     8821 catacaaatg tcgctttttt ctttgcgatg acaaacctct ttctatatct ctaactcaca
     8881 ctcaatcact tggcaaaaat caatcttctc atttggcaca aactggcgca tgagcattcg
     8941 atgagcaaca actaccacag tctgatgttc tcgatactta gacatacatt ctagaaaccg
     9001 agacttcatt tccgtagctg tctcatattg aataggacta ttaggaagca actccccctt
     9061 gttttctaaa aacagtcttc tagctgtttc aaagttttct attcctgttt tatagacctg
     9121 ccattcatgt aataaaggct ctactcttaa aggaagaccc gtagcacaga ccacatacga
     9181 agccgtttct aaagctcttg tgactgcaga agatacgatt atttcagctg acgagagtaa
     9241 aggatttttg ctcaatttct ggacttgctg ccgtcccatc tcagacaagg gtgccaaatc
     9301 tatcccaaat cctatataag aacgctcctc taactcacgg taatctggct ccccatgacg
     9361 tacaaagata atcttcattc tagtgccctg tcgatccaaa tccaccagtt cgaacgccat
     9421 cagctgcatc tccatctgca attaagaaag tagcaaaaac agcctggaca atacgctccc
     9481 caacttcaag aacaacctct tggtctgtga tattcttcat ctgcgcaaaa atatgccctt
     9541 catttccagg atttccataa taatccccat caatgacccc aactgagtta attaaaacca
     9601 agcccttctt acgaggattt gaagaacgat catagaggta gagaacctca gtcggctgca
     9661 tataagcctt aacccctgtc ggaaccaaga caatctctcc tggcgcaaca actgtacgca
     9721 cagcaacctt taagtcgtaa ccagccgcat gcgctgtctc acgcttgggc aataaatttt
     9781 catctgtaaa actcgaaacc aattcaaaac cacgaatttt cataattttc tcttttctat
     9841 tatcatttat tctagattat tctatcttat ttattcggaa aaagcacgaa aaaaagagca
     9901 cacaattcaa atcgcttagg gctgctggat tcctcccctg acccgcttca cgcagaactg
     9961 ttgctccact atttattata tcacattcct attcatttta aaagcaaaat tattttttcc
    10021 gtctatttct aaaaaaatcc tgcatgatag ctgcgcattc atcttccaaa attcctattt
    10081 caacctccac acgatgattg agacgctcat ctgtcaagat atcgtacaaa ctcccagcag
    10141 cgccaaattt ctggttttta gccccataga ccacatttgg aatgcgggca agcccaatcg
    10201 ccccactaca catgacacaa ggttcaatgg tcacaaaaag tgtgcaatcc agcaagcgcc
    10261 agctctcctc actcaagttc gcatcctcta tagccataat ttccgcatgc ataaccgctc
    10321 gctgtaattc ctcacgcgca ttatgcccac gaccaatgat ttccccatct ttgacaatca
    10381 cacaaccaat tggaatttca tcgtgttcaa gagcaatctc agcctctctc aaagcctccc
    10441 tcataaagac ttctttttct tcaagcgtat aatacatctc ttttctcttt tcctacttat
    10501 cgattttatt attatatcat gaatcccaac acaaaaaaag ccaccgaatg cggtgactct
    10561 atagggagat tattatgaaa aagaaaagtt taggatattt gttacaacaa gttaggaggt
    10621 cttcttgtaa ccgtctatag tatacccgac ctatcttaaa caaatcttaa aaatctctta
    10681 ggaccaaaca ctttctaaaa tatttgtttg ttcacgacca ggacctactg agaaagtaga
    10741 aatacgaacg ccaaccaatt cactcacacg acgaacatag ttacgcgcat tctcaggaag
    10801 atcttccaaa ttgcgaactc cggtaatatc ttctgaccaa cctggtaact cttcatagat
    10861 aggcttgcaa cgtttcaatt gctcaagact agctggatag tagtcaatac gttgaccgtc
    10921 aagatcatag gccacacaga ttttcacagt atccaaaccg ctcaaaacat caatagagtt
    10981 caaagaaagg ttagtaatac cagaaacacg acggctatga cgcatcacaa ctgagtcaaa
    11041 ccaacctaca cgacgtggac gaccagttgt tgtaccatac tcatgaccca cttcacggat
    11101 acgttctccc acttcatcaa acaactcagt tgggaaagga ccatctccta cacgactcgt
    11161 ataagcttta catacaccta caaccttgtc aatcttgctt ggaccgacac cagaaccaat
    11221 tgtcacacca ccagctacag ggtttgatga cgtaacaaat ggataagtac cttggtcgat
    11281 atctagcata acaccttgtg caccttcaaa aagcacacgt ttgccattat caagcgcatc
    11341 attcaagata acagatgtat ctatcacgta tttcttgatt tgttgaccat attcgtaata
    11401 ttcttcaaaa atatcatcga aaacaatcgc tttactgtca tacaattttt caaaaagacg
    11461 attcttttca gcaaggttac gttctaaacg ctcacggaaa atatctttat ctaaaagatc
    11521 tgcaatacga attccaacac gagcagcctt gtccatataa gctggaccaa ttcccttaat
    11581 tgtcgtacca atcttattgt cgcccttagc ttcttcttgc aagcgatcca actcgatatg
    11641 ataaggcaaa ataacatgcg cacgatcaga aatacgcaag ttatcagttg ttacaccttc
    11701 ctcatgaaga tagctcaact cttttacaag agatttagga tttacaacca taccattccc
    11761 aatgacagat attttttcag ggaagaaaat cccagatgga atcaagtgca acttaaattt
    11821 cttaccgtca atcacaatcg tgtgaccagc attatcacca ccttggtaac gtgcaatcac
    11881 ttctgcattc gctgaaagga agtctgtaat cttcccttta ccttcatcac cccattgggt
    11941 acctacaaca acaactgaag tcataatttt gtctgagccc tcaggctctt cctttctcac
    12001 atacatggca ggactctcac ctgcaattat atcttacaat ttattataat aaaaaatcgc
    12061 ctttttatca agaagaaaca atagaaagat ttgctatttc caactattaa aaaatgattt
    12121 agaaaaatta ctagctattt actattatct ttccataaaa gagtaaatta gttcggaaat
    12181 ttactaaaat tacctcaaca agaaataaaa ccccgattca ttaccaattt ttcaagatac
    12241 aaacgataag caacacgata atggtaaaca ataaaatcct tacgacaacc aatgccatat
    12301 ctcactaaat aataaattaa aaatttaaaa tgaacatgtt cccagtcaaa attatcacca
    12361 aatgtaggac catactcttc ttcaatacta tcatagaaat tagccatctg ctcataaatt
    12421 ttttgtaaca taatcaaata ctccttttct tttttataaa cttattctaa caaaaaattt
    12481 tacacattca ctatcaattc ctgaattgtt aaaataccag cctcaacaag ataaaaatag
    12541 gaaaagttga caaaatagaa acaaatttgc tacctaaatt tcaaacaatt aaagttctaa
    12601 aaagaccgcc ttaaaacttt tgggtaaatc ctattagaac tataatattt ttatataggt
    12661 attatggttc tgattttcta gtataaaaaa attcaaacta gaattcttct tagaaaaggc
    12721 cgttttaagt gctatcattg ctcaaaaatg gagctcgctg agacttctat cgtcaagaag
    12781 aatcatcaaa ttccttgtat catcaaccaa aagattgctc agaagctaat tgaaaagact
    12841 tctatgaccg acattgatca tcagttgtct atttcaactt caactgtcat tcgcaagatc
    12901 aatgattttc actttgagca tgatttttcg cgtcttcctg agattatgtc ctagtacgtt
    12961 gaaacagtcc agggagtgac tatttcaatc gggagatgga gatgagcttt attgctcagg
    13021 actttgataa gctcaatatc ataactgttc ttgagagcag aacacaagcc atcatccgaa
    13081 atcccatgga tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagtcgtaa
    13141 actgagtgat aaacattttt atcgtcctac ttttcgtatg cacttaacca ataaagagat
    13201 tttaaacaag cttttgagtt attcggaaga cttgaaacac cactatcaac tctatcagct
    13261 cttgcttttt cacttccaga ataaggaacc agagaaattt ttcggactta ttgaggacaa
    13321 tcttaagcag gttcatccta tttttcagac tgtctttaaa accttcctca aagataaaga
    13381 aaagattgtc aacgcccttc aattacctta ttccaacgcc aaactggaag ccaccaataa
    13441 tctcatcaaa cttatcaagc acaatgcctt tggttttagg aactttgaaa acttcaaaaa
    13501 agaaaggacg aaatttgtcc tttctaaatc ttcgctttct tcaacccact acagttgaca
    13561 aagaaccgaa aaatgtctcg cctctaatat agtcaattga aacaagaaca agacaaaaga
    13621 gcctcgtaaa aggtattgca acttggtaat acctttttga ggtgcttttt gatatgagcc
    13681 catgttttct taataggatt gtactcaggt gagtagggag gaagaggtaa aagttcatgc
    13741 ccaaactcct cgcataaaag ttctagctta cccattctat ggaatcttgc attgtccata
    13801 atatagtaga ttgaaactag aatagtacac ctctacttct aaaacattgt tagaattcga
    13861 ttttactgtc ctgatcgatt tgtcctattc ttatttcatt ttactataac acgaaataga
    13921 ttattattac ataacaaaaa agaggtctaa acctcttaac taaattactc cgccagtagg
    13981 actcgaacct acgacatcat gattaacagt catgcgctac taccaactga gctatggcgg
    14041 atta
//
LOCUS       DAVLIK010000046        13878 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLIK010000046 DAVLIK010000000
VERSION     DAVLIK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.046"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(1..633)
                     /locus_tag="VXE87_001657"
                     /pseudo
     CDS             complement(1..633)
                     /locus_tag="VXE87_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(736..960)
                     /locus_tag="VXE87_001658"
                     /pseudo
     CDS             complement(736..960)
                     /locus_tag="VXE87_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1496..3223)
                     /gene="ezrA"
                     /locus_tag="VXE87_001659"
     CDS             complement(1496..3223)
                     /gene="ezrA"
                     /locus_tag="VXE87_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0843173.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEEKKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPPQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(3305..5251)
                     /gene="gyrB"
                     /locus_tag="VXE87_001660"
     CDS             complement(3305..5251)
                     /gene="gyrB"
                     /locus_tag="VXE87_001660"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0843174.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(5266..5829)
                     /locus_tag="VXE87_001661"
     CDS             complement(5266..5829)
                     /locus_tag="VXE87_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0843175.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5914..6468)
                     /locus_tag="VXE87_001662"
     CDS             complement(5914..6468)
                     /locus_tag="VXE87_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0843176.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(6479..7702)
                     /locus_tag="VXE87_001663"
     CDS             complement(6479..7702)
                     /locus_tag="VXE87_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0843177.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFCMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7739..10189)
                     /locus_tag="VXE87_001664"
     CDS             complement(7739..10189)
                     /locus_tag="VXE87_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0843178.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVFLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(10389..11318)
                     /locus_tag="VXE87_001665"
     CDS             complement(10389..11318)
                     /locus_tag="VXE87_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0843179.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKIDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQVFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            11458..11745
                     /locus_tag="VXE87_001666"
     CDS             11458..11745
                     /locus_tag="VXE87_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0843180.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11779..13113)
                     /gene="ciaH"
                     /locus_tag="VXE87_001667"
     CDS             complement(11779..13113)
                     /gene="ciaH"
                     /locus_tag="VXE87_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0843181.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEINFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13103..13777)
                     /gene="ciaR"
                     /locus_tag="VXE87_001668"
     CDS             complement(13103..13777)
                     /gene="ciaR"
                     /locus_tag="VXE87_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0843182.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         4209 a         2939 c         2458 g         4272 t
ORIGIN      
        1 ataatcatat ggataagctt gtgaaagctc ttctaaaaag acgttcatcc actcagtatt
       61 acatccacca gctcttaaga aaaatgattc gcctgtatag gcatcaacag ctccataaca
      121 atagcgaaat tctcgtatat agtgactatg aacatgtgga cctactccta tttgagacca
      181 acaagatccc agtttactga ttctaccgaa accagcttca tcttggtaca tcaagcgaac
      241 cttacgaaaa cgtctactgg ttttaaagcg ctttcttgtc ttctttaatt gagattttat
      301 ttttagacac gacaatggtt tgagcgtctg ctttcttagg atgttctgga cgtggcataa
      361 tatttcgcca atcatggcgc ttcaacagtt gatagaaggc atcacgtgtg taggaacgac
      421 ctaactcctt tttataagcc tgaaataagg catcaattgt aacaaattct cctgcctctg
      481 cagccttcaa atggcgggca agaaaggctt tttcttcctc aactgtcata tatgatggtt
      541 acgaccacca cgtgtttctt gaaggagaga gtcgagtccg aactcctcat atttttttac
      601 atttcgccaa atcgttgttt gattacagtc tatagtgtat tgaatctatg acagtacacc
      661 ttggctgcta aaatatttct ataaattaat ttgactttcc tgatagagtt gttcacatct
      721 tatttcaaac cactataaaa gttctataat ctctttataa gatttgccca tcaggcgaaa
      781 tataatagat tgaaactaga atagtacacc tctacttcta aaacattgtt agaaatcgat
      841 ttgtcctgtt cttgtttcat tttactatag aacgatttga aggcgtttat aatatttagc
      901 tgtacgagag tcttttaaaa gtgttttgat ggtttggatt tcttctttag ttgatttcat
      961 atcactatta tataatgctt tttgatttta gtctagcata aatagcgaga aatatctatc
     1021 ctatcttcta gaatgtcttc caaacgagga aactctcgta aacaaagagg ttttagaggc
     1081 ctatttaccg tggactaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg
     1141 aactatccgt gagttctcta gtctggagat ttttcaatat acttcgttat tggacggtta
     1201 ccaagttact caaagtacag atttgaagct gcagataaga ctgacgaaat cactttaata
     1261 ctaaatgaaa atcaaaaagc aaactaagaa gctagcctca ggctgtactt gagtacggta
     1321 aggcgacgct gacgtgattt gaagagattt tcgaagagta taaaacactg ttttgaggtg
     1381 gtggataaat cggctgggta aaaactcaat ctcaggagaa aatgaagtaa atctccccac
     1441 aactatagaa aaagatttga ttctgctcct cacacaataa aatctttttc ttttattaaa
     1501 aacgaatcgt ttcacgtgtt ttctcatatg aggtaacaaa gcgattagtt acaccaggct
     1561 ctgccacttc caatgcttga gaaatcttgt caaatgaagc gtgataatca aattcttttt
     1621 caaaaatatc taaagcttcg ttaaatgctt cttgaatgcg ttcatcaaat gagcgatagc
     1681 ggttagaata ttgcaagagt tgctctgtca aagttgcata ttgtacaata ttataagttt
     1741 ccgtttctaa agcttccata tcattcgttg caatttcaag aactcgggta acagattcaa
     1801 tgttaatcat tttttgttct aactcaacca ttaaatcctc ggtattattg cttgccgtaa
     1861 agaataactt caagaaagtt tgtggaatac ctggcagatt gcgtttttcc atgtatcgct
     1921 tgatagtatg gagacgattg acataaacat tggccttttg acgtgcatta atatcatctt
     1981 tctcaatttg tgtcaggcgc tcactaactg aaatttgctc atcttcaata tcttttagtt
     2041 gagtttgtaa atcctcaaga ttttcttcaa gaactgaata agcttggggt ggttcttctt
     2101 gatttgaagt tacctcaaca atagctgcct caaaactctc taattctgtc tgaatacgac
     2161 gaacatggct tgcagctgtc tcaggaagta aataggtctt gttcaaacgt gcaatatctt
     2221 ctcccaataa agtattattc tctttcatat gttgaagata agttggaaga gttgcaagta
     2281 gattttccac tactttctga gcagcaattt ctcgagtaaa aatatcatac aaggcattga
     2341 tttcctcttg tgcctgtcca ttctcatatt cggcattatc caattccaac tgacgaatat
     2401 tctcttggtt tttcttgaat gcttcataaa gcaagtggaa acgcgcttca atatccgttt
     2461 caacaaaatg ataattagca tcaattagtt tacgataacc ggcttccaaa tcctgtaatt
     2521 gatctggcaa ttctgtagaa agcgtcgtaa ccaaggctgg aacacgatcc acaatatgac
     2581 ttaaggccaa aatgtgattt tctgtattat ccaaaatcac tgcggcttcc acagggtcac
     2641 ccgatgaatt caaggttaca aattgtgaaa attcagattg gatattttct aattgttttt
     2701 caatttcatc caaggcttga ccatactgtt ctgaattttc agcaactcta tgctgaagtt
     2761 cctcaaataa atccaaagca tgaagaacac gaccactatt tttagattct tgcttctcta
     2821 agtctgccaa agcattgcga attgccgcaa tatcttcttc aatcaaagta atttgactct
     2881 caatttggtc aatttgatga ctggccttga gaaaacgaaa tgaatggtta taaccttctg
     2941 cttcaaagag attattttca atatcggcaa aagagttgag agataaatcg acccattttt
     3001 gattccattc acggaaagcc acttgacttt gtccaatcaa gtgcatattt tttacagctt
     3061 ctacttcatc atttactgga agattgtata gttcttcttt tttttcttct agcgcctcta
     3121 atctcccctc gtttcgctta cgtagaaaga ttgccactac ataagccaga actaaaatga
     3181 ctgcaattgc aaccattaaa taaattagtt gtccattaga catatcaaac tcctttttta
     3241 cttgaaacaa tcgtaacgat tatatcatat tttttagacc aagggaacta cttctcccta
     3301 ttttttagac atcaagtgta ctatagacag cattttcttc gataaactca cgacgaggct
     3361 ctactcgatc ccccatcaac atatcaaaga ttttatctgc ttctgcagca tcatctacag
     3421 aaactctagc catcaagcga tgttcgggat ccatggttgt ttcccacagc tgatgatcgt
     3481 ccatttcacc tagcccctta taacgctgaa tagtcggttt ggtacgacct tcactataac
     3541 gggctaaagc ttcttggagt ttgatttctt gatctgcacc cggctggata tattctttaa
     3601 tctcgcttcc aaccttgaca ccatagattg gtggttgggc aatataaaca taaccagctt
     3661 ctaggattgg tttcatataa cgataaatca aggttaaaag aagggtacga atatgggctc
     3721 catcgacatc ggcatcggtc atcaaaacga gtttttggta acgggctttc gaaacatcaa
     3781 attctgcgcc aaatcctgtt cccatggctg tgaaaagact acgaatttct tcgttagcta
     3841 gaatcttatc catacttgct ttttcaacgt tcaaaatctt accgcgaatt ggaaggatag
     3901 cctgaaactc acggttacga ccagatttgg ctgatccacc agctgagtct ccttcgacga
     3961 tgaagagttc tgtttcagca gggttattag aagaacagtc tgctagtttc cctggaaggt
     4021 tggaaatttc caaaccagat tttttacgtg tgacttcacg cgcacgcttg gcagccacac
     4081 gagccttggc agctaaaatc cctttttcca cgatacgttt ggcaatctgt ggattttcca
     4141 tgaggaaatc ggagaaggct tcactgaaga ggcgattggt aatcttgacc acttcgctat
     4201 ttcccaattt ggtcttggtt tgtccttcaa actgtggatt tgggtgttta actgagataa
     4261 ctgcagttaa tccttcgcga acatcttccc ctgttaaatt atcttcattg tctttcagta
     4321 acttattctt acgagcataa tcattgataa cacgagtcag tgccgtacgg aaaccttgtt
     4381 catgcgttcc accttcatgg gtatgaatat tattggcgaa actcatgaca ttttcatggt
     4441 aacctgttgt gtactgcatg gctacctcaa ctgtaatatc atccatctca ccgtctgtat
     4501 agattggtgt atcaaagatt acatccttgt tctcgttgat atattcaacg taactagcaa
     4561 tcccaccttc ataatgataa tgcttggttt gttccaaacc ttggcgctta tcagtgatag
     4621 aaatttgaag accgcgattt agaaaggcca actcttgaat ccgtttattt aatttatcaa
     4681 aatcaaaggt tgttgtttca gtaaagattt ttgggtccgg tatgaagtga accgttgttc
     4741 cagttctatc tgtatcccca accacctcaa ggtctgcaac aacatgacca cgacggtatt
     4801 cttggtaatg aatcttaccg tttttatgga catgaacgtc taattgagtg gaaagggcat
     4861 taactactga cgaccccacc ccgtgaagac cacctgaaac cttgtatcca ccaccgccga
     4921 actttcctcc agcatgaagg actgtaaaga cggtctcaac agcaggacgg cctgtttttt
     4981 cctgaatatc gactgggata ccacgcccat catccacaac agtaatcgaa tcatctggct
     5041 caataaaaac ttgaatatgg ctggcaaatc ctgccaaggc ctcgtcaatt gagttatcaa
     5101 caatttccca gactagatgg tgaagacctt cttttgaggt tgatccaatg tacatccctg
     5161 gacgcatacg aacagcctct aagccctcta aaacttgaat ttgactggca tcataatcct
     5221 gtgcctgcag atttttgatt tcttctgtca tcttattcct ttttcttata tgtctaatac
     5281 ttgtcttaaa ttcacgatac tggtaaacaa gtgggtatca agtcctgcag cttgacctgc
     5341 ttcgatatca atcggccgat caccaatgac aagaccagag ctaatctgat acttttctct
     5401 taaataaagc atggattcgg gatttggctt tctcttaaag cctgagctag aagtcaccac
     5461 ttctgtaaaa taagctgcta tagaggtttt ttctaaaatt tccaaaacct gatcatttcg
     5521 atgagagacc aaaaaatgac ggccaccttg atttaaaatg tcttccaata ggtcagaaac
     5581 tccttcaaat aaaatcgggt gttcaagctc tctggcttca ttttccttgt acttttctaa
     5641 aaaattctct aaattgggag cgaatgtctc aatcgcaaaa ggagtagaaa cctttaaagc
     5701 ttgatagaca ctgtcatggt cttgtgtgat accatacagt gccaatgttt caacaaatgc
     5761 agctgttgaa gtttcataat tatccagtaa agttccacct aaatcccaga tgtaatcgtg
     5821 atatttcata cccttcatta tagcattttt ttatgaaaaa agcgatgatt tccctgagtt
     5881 ttccacataa aaaacgagag aataactccc gttttactga tttttaccaa agacatctcg
     5941 atagagcatt cctgttcgta aactctctgc gtcccctcct agttgctcca ccaactcgta
     6001 ggcaaaggca agggctgttg aaggaccccg actggttgtc aactgaccat ctaccactac
     6061 tgtttccttg acgtagtgac catcaaggat ttgctcttga acgccgtcat aacaagtgta
     6121 tcgcttattt ttcaatatct ctgcttgatt gagggcaatt ggtgccgcac aaatggctgc
     6181 tagtttcttc ccttcttgct cgaagctttg caattcttga atcaaggtct gattatcacg
     6241 taaatgtgca gaaccaggca tacctccagg aagaacaatc atatcatagt ctgataaatt
     6301 tccatcaaag acatgatctg ctcttacttg gattgcatgc gaacccgtta cttgctcttc
     6361 aaaaccaacc atatcacatg tgatattggc tcgacgcaag acatctacaa ctgtcaaggc
     6421 ttcaatttct tcaaagccct gagctaacat aactgctact tttaccatga ttttctcctt
     6481 atttaatttg ttttaataca acctttttcc gtttgaatgg gacttttccg ctcttttctt
     6541 cagctagatt agtctggtaa ctcatcgata aaagcaaacc aacaccaatc agattactga
     6601 taatagctga tcccccttgc gaaatgaaag gcaagggaat ccccgtcaaa ggaagtagtc
     6661 cagtcacagc accgatattc tcaaagatgt ggaagagcaa catcataatc aaacctgtgg
     6721 aaatataagt gtagaactgg ttatttgatt taagagtaat cttcaacata cggtaaatca
     6781 acatgagata gagggcaata accaggacag agccaataaa gccaaaatct tctgcaataa
     6841 ccgtaaaaat catatctgac tctcgaactg ggataagcag attcgaagca ttaaatccct
     6901 gaccaaataa gccaccactc ccaatggcaa tctgcccttg agcctgctgg taagtcgttg
     6961 tttgggcaaa ctcaaaggga ttgagccaag ccaaaatccg attaatttgg taggtcggca
     7021 ttccaatctg gtgaagaaaa gctcgtccgt ccttgctaat aaagatagct aagaaaccag
     7081 caactcctgt tacagcagtc acaaatactg ggataataat tttccaagaa acccctgata
     7141 ataaaacgat tcctgagaaa atggctacaa aaaccaaagc cgtccccaag tcactttgaa
     7201 gtgctaaaag aactaggact ggaatggtaa agagaatcat acagaaaatt aacaaaaagt
     7261 ccagcggaac cgtgcgtctc cattccttat gtttctttgt aaattggaca atgacacgag
     7321 ccaacatgag gatataggat atcttcataa attctgacgg ttggaatagg gtaattccat
     7381 ttattgatac ccagtttttg gcacccgttg atgcaactaa gcttggatta taaaatacaa
     7441 tcggcaagat cataagtccc aagcctaaaa tatatagaaa gggggtcacc ttccaaagaa
     7501 attctgtatt aaagagcatg accacaaaac caatcacaag ccccaaggca atccaggcga
     7561 cctgctgccc taaaatgggc agaatattat tggggtaatc atgactaacg gctatataga
     7621 tagccaccac accgatgacc agtagaaaaa atactggcaa gagcaaactg taatcgactc
     7681 ttgagtcgag agaacgtttc atatatacta accttatact ttcatacaat actatttatc
     7741 aaagttcatt aaaaaatcta tcaatagcct cgtcaacttc ggatcgagag atggttttaa
     7801 cagtcgcttc ttctgctaga gatgctacta tttgtttgcc gtatcgtttt ccgacgattc
     7861 tcctatccaa aataagagtt aaggaacgtt ggtattcacg tctcatactt cttcccaaag
     7921 cctgttttaa acgaataatg gccattggca attgataatc ataaaaggca tttttccctt
     7981 cttgattcag ttcttgatta atctttttcg tcaagggttc ttgaggattt tggaaaggaa
     8041 gcctcggtac aacttgaatc acaaaaggat ggcttgaaaa atcaactccc tcccagaaac
     8101 ttgctgcacc aagcaagatt tgttgttcac ctttttcaaa gcgtttcttt agctgatgaa
     8161 catccccatt tttatactgg gccaagtggc taactgtaag taaatccgat actgctagaa
     8221 gcatgtcttt agcggtaaag agaaccaaaa tcggttgctg gaaagcttga atttccacta
     8281 gtaaagcagc tacctctctg gcatagactt ctaaggaggt ttctgttacc agagggaaat
     8341 ctttgaccat gaccacttct tgttcctgtt ttccccgaga ttcaatcttg acaaatttag
     8401 cttcaggata gcctaaaagg tctgccaaag aaaccctctg actaatctca agagtagccg
     8461 atactcccag gacttggcaa ctctcaggaa gtaaagagga cagaagagta cggcctgatt
     8521 ttgtagaaga aatctgaatt ttcttttgac tcgtttcagt tacttcaagc cagtaatcac
     8581 cttcagctgt aaaatagcga accagctcat caaagccttc tacttctaat tctgaaaaat
     8641 actgatggag attgtccaga gaatctaaga tatttttcct agatttacca gactgaaatt
     8701 gttctatcaa gtagagacac tcaaagcgaa tactttctag tatccgttgt tgaaccctgt
     8761 tttcttctcc tactaaagcc ttatcaatta aatcgataat agattgtata tcgtaggtct
     8821 cttgaagcag attttctaga gctaacaaaa tcttttggac ttcatcaata atcagtaaac
     8881 ggtcactgac aaattcagga ttatcttcaa gtctggtcac gagataggca tgattagtca
     8941 ctaaaagctt gcaagtctct gccctttctt gactacgttt ccaaaaatct tccgtcacaa
     9001 ataagctctg ggatgataaa ttcccatcat gacgaaggtc tgctagaaaa tgttggtaac
     9061 ggtagagttg cccgatttca tccaaatctc ctgtctctgt ctcagtaagc cagaccaaga
     9121 cttgcatttt aaagcgtcta aataagcgat tttcatcatt ttcctgcaag gaatgataaa
     9181 aggcatccaa cttcagataa ttttgtggtc cctttaagct atgaatatct gtatggaaca
     9241 cttccttgag acgtttacct tcttcttcca tgatttgatt ttgaagaatc tttgtcggaa
     9301 cactaagaac aatttgtcgc tctttggatt gagataaagc gggtaagaga tagccatagg
     9361 ttttcccaat ccctgtcggc gcttgaatca gaaagacagg ttcatctttc aatagcaagc
     9421 caacctcttt agcaaaactt tcttgttcct ccctcacttc aaggttcaac agagaaatat
     9481 ttttagaaaa gtcttgagat agttttcgta gctccagaga agctgccgtt ttcttaaaat
     9541 acagaccttg aacttggacc aagtctggag aactcaggat agattggttg cgataagttt
     9601 cctcaataac caggtaggac tcatatagga gagcgtcagc catttccagc aagcgttcca
     9661 agagaccttt aggaagctgg gtcatctttt cccgtaaaaa aagaagtaat tctgctgtag
     9721 cttgggcatc tgaaagggct gtgtgtgcgt gtttaagagg aattcctaat tctcgacaca
     9781 aaatcggcaa gctatatttt tccagttcag ggaaaaagac ctgggccaat tcgaccgtat
     9841 caacacgagg gtttcttagc tcatagcctt caaaaaataa attttccgcc aagagattag
     9901 catcaaactg aacattatgg gctacaaaaa tcccatcctc caccaagtca aatatttttc
     9961 tggcaacttg cgaaaaatca ggtgcttgcg ccagacgttg gtctgtcaat cctgtcagtt
    10021 ctttgatatg agcatccaag ggttcatgtg gattgacatc cgtcgtatag tgatcgacga
    10081 tttctccgtc ctcaatcacg acaattccca cttggataat tttagcctta ctacctgtgc
    10141 tagttgcctc taaatccacc acaacatagc gattaccaat cgttttcatt ataaaaaatt
    10201 ataccaaaaa aagggccatt tggcacctgc aaacatagga taattttcaa actcaagaac
    10261 actacttttc ttaaaaatcc catcgaatag agcattctag cctgctgatt tttgtaaaat
    10321 agtgaagaaa tacgaaaaat tgagagaaga aatgtttgca tcttccttct ctcaacgaat
    10381 catgtatttt atctaaccat gtcaggatcg tagtcataaa atcctgtatc aaggaaacgg
    10441 tttttagggt gaagtttacg aacttcttca tccagcaaga agacttgatc atggctaaag
    10501 ttgccctctt gaatcaagtt acgcgcttgg ataaagagtt ttgcaatctc aacaaagttc
    10561 tgaccaggag tgtagagccc ttctagtttc cagcgagtaa agccatgctc caccaattct
    10621 gttaatttga tcatcaaatc aaggtcattg ttggcaaaga tatgggtccc atgattatct
    10681 tcaaaaatgg aatagtggct ctctggatca cttggctcag ccaagaagag gtcacgttta
    10741 tgcgtctttt catcatcgat atgtgtaaag ttatagtagt tttgcaagag tggacgttta
    10801 gaatgatgga tgacgctagc accgtaaacc aaaacttcag caggaatttc caaaatctct
    10861 ggcattttga aaagttcagc tgatggaatt tcacgcgcca aaacagcctc agatgcgcca
    10921 gccttttgtc cccagaagtt aatctgacga ctgctagtta ccatggttga agcatcgtag
    10981 atggtcttaa atgaataacc atcgcggtta actacgtaaa agacgcctgc atccccaatc
    11041 gtaatatagt ctatcttgat ttcttccaag aagtctaaga aaggcttgat acggtccatc
    11101 atatcttggt gcataagagc attgaccgca acgatcaatt ccttaccagc atcatgaacc
    11161 aacttagcga tttcacgtaa ttggtcataa ctaaaggtcg ttggcagacg aaggccaaaa
    11221 tctttctcac cgacatagat acggtctacg ccagcttcga gtagttgttc aacttgttca
    11281 atactttcag cagttgctgt aatgacaatc ttttccataa gaaaaattat accacatttc
    11341 tccaaaatca tccatgcttt gaaaatgaaa agggacttta ttctttttgt aacctttctg
    11401 taataattct ctgccgaaaa aatgataaaa taggtatgta ctgttaagga gagaattatg
    11461 cccgtaagaa aattacaatc ctatgaggta gactatcaag aagaattaaa ccagcagctt
    11521 cctcattacc aagcttatac acctgaagcg caatctgatg ccaatctcaa ggaaatccta
    11581 ttttttatta atatcgctgt tttttgtatc tgcattgcta tctttagttt tatcttttta
    11641 gcattaaaat tatcaactgc tcttgccttt gccgcagcaa tcggattcag cttacttgtt
    11701 ttaaaagttc aacggtctat tatcaaacga aaacgtagaa gataaatcca aaatatcgcc
    11761 ccagttggag cgatattttt attttttctt tttagatggt gtctgaatgg caatcttcac
    11821 ttcaaagatt gttcccttgg gtttattatc tttgacagta acagttcctt ttagagcatc
    11881 tacaatttgc ttggctaggg ataatcctaa accaaaacca cctttttgcc gggttctagc
    11941 tttgtctact cgataaaaac ggtcaaaaat tttcttttta tcttctgtcg aaataccgat
    12001 tccattatca gaaacaagta aataaagatt gcgatcggtc gccgagataa gaaaattaat
    12061 ttcaccatcc tcctcagtat acttgacggc attatcgaaa agaatggtca tcagttgttt
    12121 cagaagaagc tgatctgtga caattgttcg atggatacga ttttcaaaac ggaagacacg
    12181 attattttcc gaagcaatca tctcgtagtt tgtgaaagtt gtattaaaaa agctagttgg
    12241 aacttctgca agctccggct taatcccatc atctctccga gctaagttca gcaagcttgt
    12301 cgttaaaaaa cgcatatttc ggacttcttc caaactcgat gcaatgcttt cgctcacatc
    12361 cataatggta gcttctggct tacgaaaaag ggtctctaag cgattttgca aaactgcgag
    12421 tggagttcgt aactcatgac tggcattttc cacaaaagac tgttgcttct gcatactctc
    12481 aagcaggggc ctaacactga ccctagctag atagagactg gcaagtaaag acaaaatcca
    12541 gaaactagcc atcacgacca caatcaattg ctcatgcttt tgactagcct gctccaactg
    12601 actggtatta atcaagacag cagcatactt gatattggtt gaaaccgaac taatattggt
    12661 ctccatcaaa atcacacgat agatttcttc ctgcccatag ctattaaaaa cctgaatctg
    12721 gtagatatgt cctagttctt tcttttctaa cttaatctta tccaagccca aaaatcgatt
    12781 tccagaaaga agttgagtaa agtctttatc aaagagaatg acttccgtat tggaactgac
    12841 attaggtttt atttctactt tactagcgtc cgccctagca ttttctaaat ctttaatctc
    12901 ttctgttgcc ctatttatag ccagctgaat aactgcttga ggattttcac tcagtccatg
    12961 aagcttatcg tccaccgaag tataaagact cgaatgcatg acttgtaaaa taatcagagt
    13021 cattgtagaa aaaatcaggg tgaagacacc gaagttgcgg ataaaataac taaagtcatc
    13081 cgcataccat gtttttttaa gtttactgaa catcttttaa aagataccca acactacgca
    13141 aggtttgcaa attctctgca aaagtggttc cctttaattt cttacggact tttgaaacat
    13201 agacttcgac aaccgaaatc gttgtatcac tatcaaatcc ccatagacgg tcaaaaatct
    13261 gcgtcttagg caaaatcaca ttttgatttt gaaggaaata aactagtaaa tcgaactctt
    13321 tccccagcaa ttcgacagga gtatcttcaa ctttaacggt attggttgat aaattaacca
    13381 cgatattccc ataagtcaag gtgttttcat taaacttccc tgaacgtttg agaagggcct
    13441 gaatccgcat tttaagttct tctaggtaga aaggtttggt cagataatca tccgctccca
    13501 gttcaaatcc atgtcccttg tcatccaaac tttccttggc agtcataatc agaactggtg
    13561 tcgtaattcc cttttcacgc aattctttta agacttggaa accatttttt tctggcaaca
    13621 tcaaatccag caaaatcaag tcatagacac cactctcagc ttcgtagaga ccttcttctc
    13681 catcaaatac ctgcataaca tccgcaaaat cgtctaaaaa gtcaaatact gaatttgaca
    13741 gacctaggtc atcctcaacc aataagattt ttatcatgag aaactcctcc ttattaaaac
    13801 tattatacca aatttgcctt aaaaaaaact caactctctg cattttacgg ctctataata
    13861 tttgtagtgg gtaaatcc
//
LOCUS       DAVLIK010000047        13379 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLIK010000047 DAVLIK010000000
VERSION     DAVLIK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.047"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     regulatory      30..128
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            212..1003
                     /gene="thiD"
                     /locus_tag="VXE87_001669"
     CDS             212..1003
                     /gene="thiD"
                     /locus_tag="VXE87_001669"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0843183.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIHPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(1213..1845)
                     /locus_tag="VXE87_001670"
     CDS             complement(1213..1845)
                     /locus_tag="VXE87_001670"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0843184.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMDTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(1838..2641)
                     /locus_tag="VXE87_001671"
     CDS             complement(1838..2641)
                     /locus_tag="VXE87_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0843185.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(2641..3165)
                     /gene="thiW"
                     /locus_tag="VXE87_001672"
     CDS             complement(2641..3165)
                     /gene="thiW"
                     /locus_tag="VXE87_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0843186.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(3170..3862)
                     /gene="tenA"
                     /locus_tag="VXE87_001673"
     CDS             complement(3170..3862)
                     /gene="tenA"
                     /locus_tag="VXE87_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0843187.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKVFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(3873..4523)
                     /locus_tag="VXE87_001674"
     CDS             complement(3873..4523)
                     /locus_tag="VXE87_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0843188.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMFY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(4525..5910)
                     /locus_tag="VXE87_001675"
     CDS             complement(4525..5910)
                     /locus_tag="VXE87_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843189.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDYMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(5911..6471)
                     /locus_tag="VXE87_001676"
     CDS             complement(5911..6471)
                     /locus_tag="VXE87_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0843190.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(6733..6821)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(7030..7659)
                     /locus_tag="VXE87_001677"
     CDS             complement(7030..7659)
                     /locus_tag="VXE87_001677"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0843191.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIMKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(7661..8443)
                     /gene="thiM"
                     /locus_tag="VXE87_001678"
     CDS             complement(7661..8443)
                     /gene="thiM"
                     /locus_tag="VXE87_001678"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0843192.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVIASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(8686..9354)
                     /locus_tag="VXE87_001679"
     CDS             complement(8686..9354)
                     /locus_tag="VXE87_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0843193.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(9569..9657)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(9909..11045)
                     /gene="lctO"
                     /locus_tag="VXE87_001680"
     CDS             complement(9909..11045)
                     /gene="lctO"
                     /locus_tag="VXE87_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0843194.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPNTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(11670..13160)
                     /gene="lysS"
                     /locus_tag="VXE87_001681"
     CDS             complement(11670..13160)
                     /gene="lysS"
                     /locus_tag="VXE87_001681"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0843195.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQSTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(13288..>13379)
                     /locus_tag="VXE87_001682"
     CDS             complement(13288..>13379)
                     /locus_tag="VXE87_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0843196.1"
                     /translation="LEPMAQQVIPKAAFGYIASGAEDTFTSFQ"
BASE COUNT         4061 a         2897 c         2456 g         3965 t
ORIGIN      
        1 aaaaatatgc tatactaaag aaaaaagaaa acaaccacta ggggtgcgta aagctgagat
       61 taacgactgt tagatccctc tgactcaatc taggtaatgc tagctgatgg aagtggaaat
      121 gataatgggg actagcagtc ttctattgcc tttctaaaac agactagctt gttcttaaga
      181 atacaaactt cagttggttg ggaggtttta gatgacttat ttacccgttg ctttgaccat
      241 tgcagggact gaccctagtg gtggtgctgg cattatggca gatttaaagt cattccaagc
      301 gagagatgtc tatggaatgg ctgttgtaac cagtcttgtc gctcaaaata ccagaggtgt
      361 tcagctaatc gagcacgttt ctcctcaaat gttgaaagcc caattggaga gtgtcttttc
      421 tgatattcca cctcaggctg taaaaactgg aatgttggct actactgaaa tcatggaaat
      481 catccacccc tatcttaaaa aactggattg tccctatgtc cttgatcctg ttatggttgc
      541 tacaagtgga gatgccttga ttgactcaag tgctagagac tatctcaaaa caaacttact
      601 acctctagca actattatta cgccaaatct tcctgaagca gaagagattg ttggtttttc
      661 aatccatgac cccgaagaca tgcagcgtgc tggtcgcctg attttaaaag aatttggtcc
      721 tcagtctgtg gttatcaaag gcggacatct caaaggtggt gctaaagatt tcctctttac
      781 caagaatgaa caatttgtct gggaaagccc acgaattcaa acctgtcaca cccatggtac
      841 tggatgtacc tttgctgcag tgattactgc tgaactagcc aagggcaaga gtctttacca
      901 ggcagttgat aaggccaagg cctttatcac aaaagctatt caagatgccc ctcaactcgg
      961 tcatggttct ggtccagtca accatacaac ttttaaagat taagaaaaaa aactctctag
     1021 ttcccacttt aagggaatta gagagttttt atactcttcg aaaatctctt caaactacgt
     1081 cagcttccat ctgcaacttc aaaacactgt tttgagctga cttcgtcagt cttatctaaa
     1141 acctcaaggc agtactttga gcaacctgcg actagctttc tagtttactc tttgattttc
     1201 attgagtatt aattaggaaa gaatgtcatg caactttgtt aaaaaggctt gcgtttttgc
     1261 ctcaatatct tctgcttgca tcaaatcacg tacaacagct acaccagcta tgccagtgtc
     1321 cataagctga tcaatattct ctgatgtcaa gccgccaata gcaactactg gaatggcaac
     1381 cgtttggcaa attgttttca aggtcgatat cagagtaatg ggcgcatttt ccttggtggt
     1441 ggttgggaaa atggctcctg tacccaagta atctgcacct gatttctccg cttccagagc
     1501 tcttttaacc gttttagcgg tgacaccgag gattttttca ggacccaaga ctttgcgagc
     1561 taccgaaact ggtaattcat catctccgat atgcagacct gctgcatcaa ccgcaagaca
     1621 aacatccaac cgatcatcga ttatcaaggg tacctgataa gcatctgtta tttccttgac
     1681 ttgttttgcc agttgataat attgattggt tgtgagattt ttttctcgca attggactat
     1741 ggtaacccct gaacggcagg ccgtctcaac ttttgcaaga aagctttcca cggaatcttg
     1801 atagcgattg gttaccagat atagtctaag tgcttctcta ttcataaacc tctcctttga
     1861 tggtatctag ccaattttca tctcttctta ggagcgaaag ctgattgagt acttggtaac
     1921 gaaattcttc caatcccatt ccttgaacaa ctattttctc agcagcgata ttgagataag
     1981 agactgctaa gcaagaagct tcaaaaccag tctttccttg gctgagaaaa acggctgtta
     2041 aggctccaac caaatctcct gtccctgtta tccagtctaa ttctgcacag ccattctcaa
     2101 gtacagcaac ttgattctcc gaaacaataa ggtccttggg acctgtgact aagaatgaca
     2161 taccaggata ggtctgacac cagtctttca agacttgaag caaatcctcc gtttcttgat
     2221 ctttagcact cgcatcgacc ccaacgccgt gatgctttaa tccaacaaga cttcgaattt
     2281 ctgacatgtt tcctttaagg accgtaggtc tatagtctaa aaggtcttta actaagctct
     2341 tacgaatgga tgaagtcgtt acgccaaccg catctactac catcgggaga gaagattggt
     2401 ttgcatacaa agctgccatg cggattgctt tttccttctc agctgacaaa tgccccaaat
     2461 tgatgaagag agcctggctt tgcttagtaa aatcaagaac ttcacgggga tcatctgcca
     2521 tgacaggttt gcatcccaga gccaaaatcc catttgccag catctcacaa gaaatctcat
     2581 tggtcataca gtgaatgagg gaactagagc ctataggaaa aggatttgtc aatgcctgca
     2641 tcattctatc ctttcagcaa agaaatatcc ttgcactttt ttaaagaatt cctgcttgat
     2701 taaaaatcta aatgcaataa aggaaatcgc tgtaccaatc aaggttgctc cgaaaaatcg
     2761 aggagtgtag ataaaccaac taagcttagc agccgatcct gtaaagagca ccataacagg
     2821 ataggaaaca atagaaccaa taatacctgt tcccacaatt tctcccaagg cagaaaagta
     2881 aaattttcga ccgtacttat aaaagagacc tgctagaagg gctccaaaag tcgctcctgt
     2941 gagagctaaa ggcggaatcc cttgagtcgt catacggata aaggctgtca ctgtagccat
     3001 agccaaggca taaacaggtc ccatcatgat tcccgctaga atattgacta cactggacat
     3061 cggtgccatt ccctcaatcc gaaagatagg tgtaaggact acatcaaggg caatcatcat
     3121 agataaaatg gtcaatttgt gaacttgtag ttggtgcttt ctcatgtttc tattcttctc
     3181 ctttttctaa agactgtaaa tcgctcttcc atgtctggtg ttggtaagcc atctcccaaa
     3241 acttggcttc catatgaaca ctgatgtgga aggcatctag cattttttgc ttatctgtct
     3301 catcactttc tcgatagagc tgattgacca atgctccctc ctctctgatc tgttgctcta
     3361 actcatccgt aatataagtt tcaatccatt gttgatagag aggatttggt gatggtttaa
     3421 gattaagtga tttgcctata tcatggtata accaaggaca aggaagcaag cttgcaaaag
     3481 ctatggctaa gttcggttct gcaaattgcc tataaatatg agaaatgtaa tgataacagg
     3541 ttggagcgat tggatgttgc tccatttcct ggtcgttgat ttccaattcc ttgaaaaatt
     3601 gttggcgaat aaataactca ccctccacta aaccctgagc attttgtttc aagagtcttt
     3661 tcatctcttg gtttgaagtc ttatcagcca aaagatgata gatttctgag aaaaccttca
     3721 gatagtaggc atcctgaatc aggtaatagc ggaaaatggc aggttctaaa ttcccctctt
     3781 gtaattgtaa aataaaggga tgatgaaagg aagcctgcca agctttcttg gataattcca
     3841 tcgcaatatc tgtaaattcc ataataactc ctttataaaa atagactggt ttgaagcaat
     3901 aaaaagaaaa gcaggtagat taattttgtt tttttaggaa tataaaaagt ccgatagcta
     3961 ttcttcaact gtgcatgttc gtcatatccg tgagcagata gagctctcag gtaaagatgg
     4021 cgccacctaa agactgtcat cagaacctta ctgtaaatca agggcgacca aaaatgtagt
     4081 tcttgaccac gtaataggca agcttctttg agggacttga tttcttgctg aatgagagga
     4141 aaagaattga ataccacaat caaggcatag gaccaagagc gtgatagccc cttttgagcc
     4201 aagtacaaga gaagctcttt tagtgaaata gaggaaacaa agacaaggcc gatacaaact
     4261 gtcacaaagg ccctcgttcc aagcatgact gcctgtgaag catctccgtg taactgaact
     4321 gcccagtagt tggcaaaaga tggtaaaatg gcaagtatga tcatccaagc taacatttta
     4381 aatcgacggt aatagaacat aaagagaata caaaatgcga ctaccgaaag attcagagca
     4441 atcgaaggaa tgaaagatgt ttccaaggat aaaatcagca agaagagact gataatcggt
     4501 gtctgggttg ctactttgac catactatct cacctcccct tgggtattgc tactctgaga
     4561 tgtaagtggt ttggtaatgg tcacttcttt cacatgccga agaccctgac tagtcatctc
     4621 aatccaataa tcaaccacag aaatcaaagg gtctaaacga tgactaatga gcagaaaact
     4681 tcttccttga ttcctctcct ccacaatcca cttgcaaaaa taatggcagg ctctatcatc
     4741 caaacctgca aaaggttcat ctagcaagat cacggaagcc ttactggtca agatggtcag
     4801 gagctgaaga attttttgct gaccaccact taattgatag ggactcttat cgactgcctg
     4861 ctccaaatca aaatatcgta aagcttgaaa aatccgctga tttctttcag aatcaggtcc
     4921 atctaattga agctcctctc gcagactgac tcggataaac tgcttctcag cttcctgaac
     4981 aacacccgtc agatcacggt acaaactctt tttctttttc aggactgtcc ccttccatgc
     5041 aatgcgcccc ttatactttt gaaattgaag aatagaccga aagagggttg atttcccgac
     5101 accattgtca cccaggatac aggaaatccc ttgatagaat gtgaaatcag caatcgaaaa
     5161 gagggggcga ttaccaagct caccagtcac acggttcata tggaataatt ccgggctagc
     5221 agcaacttcc tttgaagcaa cctgtgtcat ctcataggaa gggatttgaa acacttccct
     5281 tagttttccg tctcttagct caaccatata gtcgatatag gctttatagt cagataaatc
     5341 atggtcgcac aaaatgactg tcttcccatc aagagccaac tcttttagaa tctccaatat
     5401 ctcgattcta ctcttgcggt caatggaagc gaagggctca tccaagagat agaccctagg
     5461 attcatggca aagaggacag ccagcgctgc tttttgcttt tccccacctg ataagtgatg
     5521 gatgagacgg tgcaagatgt ccttgcaacg acattgctgg acaacctctg ctattttaga
     5581 atcaatttcc tgaaggtgat agccgatatt ttccatggta aaaaccaact cctcaaacaa
     5641 gctctccatg gtaaattgat gattaggatt ttgcaagaga ataccaaccg tctggacacg
     5701 ttcgacgata gaaagctgac tgacctcgct cccatctatc aggacttgac cgctataggg
     5761 aagagaacta acttgggcaa tgacttgaaa aaggctggat tttcctgaac cactgctccc
     5821 aactaacaag gtaaaggctt gcgcatgaaa agtaaaatca aacggctcag agaagattgg
     5881 ggactgaatc gctcgtagtt ccagacccat ctatgctttt cctccagttg caaactgatg
     5941 atagagtttg acaatggcac gaaccaagat ggtacagaag aaataaacag aaataaaacg
     6001 taccacaagt aaggaaagga caaacggaag ggaaaaggcg tagtaaccta acttaatgta
     6061 ttcatagaca aagctaacaa gcgtaatccc aatactatta gcagttagag agagccaact
     6121 ttcatagcga ttcttagtta cgataaaacc aaattcactt cccaaacctt gaactaagcc
     6181 agacaaaaga gctcctagac caaattggct accataaagg acttcagcaa gcgcagctag
     6241 cacttctcca atcgttgcac ttccgactct cggaacaaag atggcagcaa tgggcgcagc
     6301 catacaccag agaccgaaga ggatttcatt ggcaaaggcc tgcaaaccaa gaggtgttaa
     6361 gagtagactg agaatattat acacatatcc tgaaccaacg aaaaccccac caaaaaagat
     6421 agacaagaaa gcaagcaaga taacatcttt taactgccat tttttcaaca taaaaaactc
     6481 cttttttaaa agaaaagtgg ggcactcaag aagaccgacc taaatacttt gtatagcaga
     6541 ttgaatttag aacagtacac aggaatgcta aaatatttct agaaattaat ttgaattttc
     6601 taattgattt gttcgcatct tatttcaatc tactatatca tcttcatcca gtttcgtaaa
     6661 agaaaaaact ctaattacag atacgaatta gagttcagct tacaagatta gacagttctt
     6721 ttcgacatac gaaaaaaaca tttcacattt cccttcgcca gtcttaactg tatcaggttc
     6781 aatgggtatc atctcagcct aaagcacccc aaatgccttt attatttaat tatgtgatta
     6841 ttataacaca cattttatac tagttcaaga aattgaactg gaaatacagc cttgcactca
     6901 caaagacagc agatctttct tttgcaaaaa acaaatgacc tgtttgatga attagctatt
     6961 caagctgaat ctagacatag ctttttaaaa aaggaaaatc ctacttactt agaatccaag
     7021 gatagatatc tattgttcac tcatttcccg aacagttttt tctatatttt ttgcatacga
     7081 tattgccgaa atgattgaaa cgccgtcaac attggtcttc ataatgtctt taatatgttt
     7141 cgtctgtatc ccaccaattg caactaaggg catttgtggc aatagttttc tcatcaattt
     7201 aacaccttca taacctatag caccaccagc atcatccttt gactgggtat caaatacagg
     7261 accaacacca acataatcta catattcaac ttttgattgt tgaaattctt cctcgttttt
     7321 tatagaaaga ccaattattt tatctggcat caattttcta atttcatcaa caccaatatc
     7381 atcttgacct acatgtacgc catcagcgtc aatttccatt gccaaatcga tatcatcatt
     7441 aacgataaac ggcacattgt attttttaca aagttcttta atttggatag ctagttcaag
     7501 tttttctaag ccttctaaag caccctcacc tttttctcga aattgaaata aggttatacc
     7561 accttttaag gcttcctcaa cgactgtata tagatttttt ccttggcaag tagtcgttcc
     7621 acaaataaaa tatagtttta gtaattcttt atgaaacatc ttacttcact cttttgaatt
     7681 cctttacatc ttcatctgta atctcgtata aggcatttat aaattcaact ttaaatgtcc
     7741 caggaagatg tccatttgga cgtttttctg ccatttctcc agcgatattg taaaccaaca
     7801 ttgctgtttc taatgatttc aattcttgac ctttttctag tccgataaag cttgctatca
     7861 ctgcccctaa taagcatcct gtcccaatga ctttcggcat catagcacta ccattatgaa
     7921 tcgttaccac ttctccatta acagcaatgg catccacttc acctgttact actattggaa
     7981 tattgaactt ctcatttgct gctagagcaa tttcgtcaat attatctacg cccgcactat
     8041 ctactccttt agatgccaca tctattccta ctaaagaggc aatctcgcca gcatttcctc
     8101 taatcgctgc tagtttataa ttgttgatta gatcatctgc tacttttttt ctatattctc
     8161 ctgctccaca ggctacagga tctaaaactg ctgggacatt atatttctct gcaattttca
     8221 gagcagcttg gtataatttc caattttcat ctgtcaatgt tcctatgttt attaataaac
     8281 caccagcata ctttaacaaa tcctctaaat ctgctggaaa ctcactcatg gctggtgagg
     8341 cgcccagtgc tactaatcca tttgctgtga aattttttac tacatcattg gttatacaaa
     8401 tgaccaatgg tgctttttct tttaataatt ttaaacttgt catattgaaa tccttccttt
     8461 tcactttata cgatctactg atttcgattt atttctatct ttcgttaaga atttttttca
     8521 tttacattga atgatttata ctcaatgaaa atcaaagagc aaactaggag gctaaccgca
     8581 ggttgctcaa aacactgttt tgaggttgtg gatagaactg acgtggtttg aagagatttt
     8641 cgaagagtct tacctcatca aatttgtaaa tatcatgagc cttctctaga catcgtaacc
     8701 aatatcaaaa aaagctaatt ctaaagcgac tgcttgattc cagcgttgct gaagttctgt
     8761 caaatcttct cgatttttac cgacacgatt gagttcgtca accagaaatt gaacccactc
     8821 tgcaaagaaa ggacctctgt ggagattgat ccattccgaa tgaatataga cttcaggtaa
     8881 agccaaatct ttagaacccc agtctaaata gagaccttct gcaatgacca gcatgaccaa
     8941 aagatgggca tagtctgatg aagccaccgc cgaatacatt agatcctgaa aggcttttgt
     9001 tacagggtgc aaagtcactt ctagatagtc attctctgct acttttaact ctttaaaagc
     9061 cttttggaaa taaccatctt catctgcttc aagaaagcct agttgcttgg caaaacgaag
     9121 cttggattca agtttatctg cgtgagctac gcaggcaccc agcatggata agaaggcatc
     9181 aaagaagtga taatcttgaa tcagatagtc ctttaagacc ttattctcaa ttgtccccgc
     9241 aaaaagttcc ttaacaaaac gatgattgat tgcagcctgc caatccttct gactgctttt
     9301 taataattct ccaacagtca aacctggctg aaatgcatag tcttgtgttt ccatatttac
     9361 ttctcctctc tttacttgtt agtaattaat aaaacaccaa gaaatatcaa gcaaaatcgt
     9421 aattccactt gatcctttta aagcacatcg agagcatttg cagagagcta actaaacaag
     9481 cctatccagt ttatataaac aaaaaactcc aattacaatc aagaattaga gttgacttac
     9541 aagattagat cgttcatttc gccatacgaa aaaacgtttc acatttccct tcgccagtct
     9601 taactgtatc aggttcaatg ggtatcatct cagcttaaag caccccaaat gtctctatta
     9661 tttaattact gaaccagtat agcaaaaaat gaaagcccta gcaagatatt tgaccgaaaa
     9721 atatctttat atagtagatt gaaactagaa tagtacacct ctacttctaa aacattgtta
     9781 gaaatcgatt tgactgtcct gattgatttg tcctattctt atttcatttt actatagttt
     9841 tcgatagcaa tttattcttc caatacacga agaaaaacct ccacattcag tggaggcaat
     9901 ctgttttatc aatacaattt taagtcacga gggtcaactg ggaaggttgg gttgtatgga
     9961 ttgtgacgga gcttgaagtg tttgacatct tcaatggtct gagctccaga caattgcata
    10021 actgtcttca attccgcatt caagtgttca aagacttgac gcacaccgac actaccaccg
    10081 agagccaagc catagatgac agggcgtcca atagcaacca agtctgctcc tgatgccaag
    10141 gctttaaaga cgtgttgacc acgacgaaca ccagagtcaa agacaatcgg cacacgtcta
    10201 tcaactgctt ctgccacttc ttgaagcgag tcaaaggcag ctggtccacc gtcgatttga
    10261 cgaccaccgt ggttggttac ccagatacca gaagctcctg cagcaagcga acgttcaacg
    10321 tcctcacggc attgtggtcc cttgacatac acaggaagac cagagtattc agcgataaat
    10381 tctacatcgc gtggagacaa gcgttgttta gctgatttgt aaacaaagtc cattgattta
    10441 ccagcacctt ctggcaggta ttcttcaaca atcggcatgc caactgggaa gacaaaacca
    10501 ttacgcttat ccacttcacg attcccccct acagtagcat ctgccgtcaa gacaatcgct
    10561 ttataacctt cagccttcac acggtccatg atgtggcggt tgataccgtc atccttacta
    10621 aagtaaaatt gaaaccaatg aggtgtccct tgaagggctt cagaaatctc tggaaggtca
    10681 acagtagagt aagaactggt tgtataaaga gaaccaaact catgcacacc acgcgcagtc
    10741 gccacttccc cctgttcatt tgccaattta tgagccgcaa caggtgccat aatgattgga
    10801 gaagatagtt tttcacctgc aaattcaatc tctgtatttg gattttctac attgcaaagt
    10861 gtatgaggaa cgatgagctt gtggttaaag gcacggatat tctctcttaa agtgaaagta
    10921 tcttccgccc cactagcgat atagccaaat gctgctttag gaataacttg ttgcgccatt
    10981 ggctccaaat cataggtatt gatgaagtct acatgacctt ctgcattgct tgttttgtat
    11041 gacataaact gtcctcctcg attaagtaag cgtttgcttt ttactataca actataataa
    11101 ctcttttttc aatcattttc aagagttttg cttaaaaacc atcttatttt ttcatacaat
    11161 atactagccc tactttcctt aaactctaaa ccttagtcta tattaagtga atcgttgaga
    11221 ttttttgctg ccaggcattt gaactacttt tttatttgct gattctatct actaatacta
    11281 taaaaaaaca agtgaataag acaccagaac atcctctaat aggacctatg gacttatatc
    11341 agtcccatat atactgttta agcaagatac tatcctagtt gacgctaact tcctatccca
    11401 cttattaatt ttttatttat agtgaatctg aacaaatcaa ttggggaatc caagtcaatt
    11461 tctagtactt tttgaaaagt ttcagcgtac tatcgtaaaa tgaaataaaa catgcacaaa
    11521 ttgcttaggg aatttaaacc aatttctaac aatgtcttag aaatcaaagt gtactatttc
    11581 aacttcaata tactacactt cattttctcc ttaaattcag tctctttttg aatcaaaaaa
    11641 tcctctggta agagccagag gataagaatt tatttcattg ttgggaagag caatacatca
    11701 cggatagttg ttgtatcagt gaggagcatg cagagacggt cgataccgat tcccaaacca
    11761 cctgttggtg gcataccgta ttcaagagct tcaatgtagt catagtcgat tcctgtcgct
    11821 tcatcatcac caagttcttt ggctttagct tgggcttcaa aacggctaag ttggtcgatt
    11881 gggtcgttca actcagtaaa ggcattaccg tactccttag tcatgataaa gagctcgaaa
    11941 cggtcagtaa agcgttggtc ttcaggattt ttcttagcga gtggagatac agctactgga
    12001 tgtccataga caaaggttgg ttggattaaa gtttcttcaa caaactcttc aaagaaggca
    12061 ttgatgatgt gaccaacctc agtgtagtgt ttctcaactg gaactttctt ctcagcagcg
    12121 atagctttag cttcttccaa agtcatgtct tgccagaaat cgacaccagt aatttctctg
    12181 atagcatcca ccatatgaac acgcttaaat ggttcgttaa tcttgatttc agtactttgg
    12241 tagttgactg ggccatcacc tttgactgat ttagcagcgt gttggataat gccttcagtc
    12301 aagtccatga tgtcttggaa gtctgcataa gcttggtaaa cttcgataga agtgaactca
    12361 gggttatgag tagcgtccat tccttcgtta cggaagatac ggccaatttc atagacacgt
    12421 tccataccac ccacaataag gcgtttcaag tgaagctcag tcgcgatacg aagcaccatg
    12481 tcaatgtttt gggcattgtg gtgggtgata aatggacggg cagcagcacc accggcttca
    12541 ttatgaagaa caggtgtttc cacttcaagg aatccttttt ggtcaaggta acgacggatt
    12601 tcagagatga tttttgaacg agtgacaaag cgttcaaagc tttcacgatt agaaatcaag
    12661 tcaaggtaac gtttacggta aattgtttca acgtctgtca aaccatggaa tttctcagga
    12721 agaggacgaa gagccttaga caagtgtgtg atgtgggttg ccttgataga gagttctccc
    12781 atatccgtac gcatcacttc accttcgaca ccaaggaagt caccaaggtc tgcttttttg
    12841 aagatttcgt agttttcttc accgacagca tccttacgaa cgtagatctg aatctggcct
    12901 tcgcggtctt gaaggtgggc aaaacccact ttacctttac cacgtttggt taccaagcgt
    12961 cctgcgatag tagctgtttc gtttttatcg tgtaattgtt ctttatcgag gttggcatat
    13021 ttatctttta attcttgtga atttgcagta cgttcaaaac gttttccgaa aggatcgatt
    13081 ccttgttcgc ggagcgcagc cattttttca cggcgaacga tctgctggtc atttagttct
    13141 tccatatgtt ctgtagacat gggatcctcc tagttttact caaaattgaa tacgatgagt
    13201 cattttttgc gataccccca ttttatcata aataagcaag aaattcacgg ataatcttta
    13261 aaaactaaaa agaacctgac gctaaaatca ctggaaagaa gtgaaagtat cttccgcccc
    13321 actagcgata tagccaaatg ctgctttagg aataacttgt tgcgccattg gctccaaat
//
LOCUS       DAVLIK010000048        13244 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLIK010000048 DAVLIK010000000
VERSION     DAVLIK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13244
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.048"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..610
                     /locus_tag="VXE87_001683"
     CDS             <1..610
                     /locus_tag="VXE87_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0843197.1"
                     /translation="PAPKTGWKQENGMWYFYNTGGSMATGWLQYNGSWYYLNANGAMA
                     TGWAKVNGSWYYLNANGAMATGWLQYNDSWYYLNASGAMATGWLQYNGSWYYLNANGS
                     MATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEAS
                     GAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            1011..2132
                     /gene="mnmA"
                     /locus_tag="VXE87_001684"
     CDS             1011..2132
                     /gene="mnmA"
                     /locus_tag="VXE87_001684"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0843198.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2273..2728
                     /locus_tag="VXE87_001685"
     CDS             2273..2728
                     /locus_tag="VXE87_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0843199.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWKGQLRHIHLEK"
     gene            2738..4651
                     /gene="mnmG"
                     /locus_tag="VXE87_001686"
     CDS             2738..4651
                     /gene="mnmG"
                     /locus_tag="VXE87_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0843200.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4855..4932
                     /locus_tag="VXE87_001687"
                     /pseudo
     CDS             4855..4932
                     /locus_tag="VXE87_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5030..6709)
                     /locus_tag="VXE87_001688"
     CDS             complement(5030..6709)
                     /locus_tag="VXE87_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0843201.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQGEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6711..6944)
                     /locus_tag="VXE87_001689"
     CDS             complement(6711..6944)
                     /locus_tag="VXE87_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0843202.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7326..7547
                     /locus_tag="VXE87_001690"
     CDS             7326..7547
                     /locus_tag="VXE87_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843203.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7760..7912)
                     /gene="cibB"
                     /locus_tag="VXE87_001691"
     CDS             complement(7760..7912)
                     /gene="cibB"
                     /locus_tag="VXE87_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0843204.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7914..8099)
                     /gene="cibA"
                     /locus_tag="VXE87_001692"
     CDS             complement(7914..8099)
                     /gene="cibA"
                     /locus_tag="VXE87_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0843205.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8277..8960
                     /gene="tsaB"
                     /locus_tag="VXE87_001693"
     CDS             8277..8960
                     /gene="tsaB"
                     /locus_tag="VXE87_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0843206.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKNLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYVGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8957..9394
                     /gene="rimI"
                     /locus_tag="VXE87_001694"
     CDS             8957..9394
                     /gene="rimI"
                     /locus_tag="VXE87_001694"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0843207.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVIAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9384..10394
                     /gene="tsaD"
                     /locus_tag="VXE87_001695"
     CDS             9384..10394
                     /gene="tsaD"
                     /locus_tag="VXE87_001695"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0843208.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10434..11740)
                     /locus_tag="VXE87_001696"
                     /pseudo
     CDS             complement(10434..11740)
                     /locus_tag="VXE87_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(12016..12367)
                     /locus_tag="VXE87_001697"
                     /pseudo
     CDS             complement(12016..12367)
                     /locus_tag="VXE87_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12474..12767)
                     /locus_tag="VXE87_001698"
                     /pseudo
     CDS             complement(12474..12767)
                     /locus_tag="VXE87_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         3788 a         2616 c         3094 g         3746 t
ORIGIN      
        1 tcctgcacca aaaacaggct ggaaacaaga aaacggtatg tggtacttct acaatactgg
       61 tggttcaatg gctacaggtt ggctccaata caatggttca tggtattacc taaacgctaa
      121 cggcgctatg gcaacaggtt gggctaaagt caacggttca tggtactacc taaacgctaa
      181 tggtgctatg gctacaggat ggctccaata caacgattca tggtattacc taaacgctag
      241 cggcgctatg gcaacaggtt ggctccaata caacggttca tggtactacc tcaacgctaa
      301 cggttcaatg gcaacaggtt ggctccaata caacggttca tggtactacc tcaacgctaa
      361 cggcgctatg gcaacaggtt gggctaaagt caacggttca tggtactacc tcaacgctaa
      421 cggttcaatg gcaacaggtt gggtgaaaga tggagatacc tggtactatc ttgaagcatc
      481 aggtgctatg aaagcaagcc aatggttcaa agtatcagat aaatggtact atgtcaatgg
      541 tttaggtgcc cttgcagtca acacaactgt agatggctat aaagtcaatg ccaatggtga
      601 atgggtttaa gccgattaaa ttaaatcatg ttaagaacat ttgacatttt aattttgaaa
      661 caaagataag gttcgattga ataaatttat gttcgtattc tttaggtacc tatcttatga
      721 tttcaggaaa tgtcattaaa aaaacgactc cttttctcta acttgaaaaa tagattagag
      781 aaaatgggtt gttttattta ttatagttat ttgaatgaag ataagaagaa ggtatactca
      841 catcattcac ataatctgta tattgactat aagttttaaa aaacaatttt taagctcttc
      901 cttgtcttct ctaaccaagc gtgttataat gaatactgct caagcgacct tcaatcgtga
      961 agcacacacg accttcaatc gtgaataaac gaatagatgg gagacttacc atgagtgata
     1021 actctaaaac acgtgttgtc gtggggatga gtggtggtgt tgattcgtcg gtgacggctc
     1081 ttttgcttaa ggagcagggc tacgatgtga tcggtatctt catgaagaac tgggatgaca
     1141 cagatgaaaa cggcgtttgt acggcgaccg aagattacaa ggatgtggtt gcggtggcag
     1201 accagattgg cattccctac tactctgtca attttgaaaa agagtactgg gaccgcgttt
     1261 ttgagtattt cctagcggaa taccgtgcag ggcgcacgcc aaatccggac gttatgtgca
     1321 acaaggaaat caagttcaag gcctttttgg actatgccat gaccttgggg gcagactatg
     1381 tagcgactgg gcattatgct cgagtggcgc gtgatgagga cggcactgtt cacatgcttc
     1441 gtggcgtgga caatggcaag gaccagacct atttcctcag ccaactttcg caagaacaac
     1501 tccaaaaaac catgttccct ctgggacatt tggaaaagcc tgaagtacgc agactagcag
     1561 aagaagcagg cctttcgact gctaagaaga aagactcgac agggatttgc tttatcggag
     1621 aaaagaactt taaaaacttt ctcagcaact acctgccagc tcagcctggt cgtatgatga
     1681 ctgtggatgg tcgcgatatg ggcgagcatg ctggtctgat gtactataca atcggtcagc
     1741 gtggcggact cggtatcggt gggcaacacg gcggtgacaa tgccccttgg ttcgttgttg
     1801 gaaaagatct aagcaagaat attctctatg taggacaagg attctaccat gattcgctca
     1861 tgtcaactag cctagaagcc agtcaagtcc actttactcg tgaaatgcca gaagagttta
     1921 cgctagaatg tacggctaaa ttccgttacc gtcagcctga ctctaaggtg accgtccatg
     1981 tcaaaggaga caaggcagaa gttatctttg cggaaccaca acgcgcgatt acaccaggac
     2041 aggcagttgt cttttacgat ggcgaagagt gtctaggtgg cggtttgatt gacaatgctt
     2101 accgcgatgg acaagtttgt cagtacattt agattgacaa attttctcaa tttgctacaa
     2161 taataacagc aatagaaatg atggtcaaag ctcatggatg ttgcaggctt ttttgtcctg
     2221 cacttctttg tagttttgac tgtttttgtg tcgtttaagg gaaaggacaa gaatgactca
     2281 acaagacttt cggacaaaag tagacaatac ggtttttggt gttcgggcta cagccttgat
     2341 tgtccaaaat cacaagcttc tagttaccaa agacaagggc aagtattaca ctattggagg
     2401 tgcgattcaa gtcaatgaaa gcacggaaga cgcggtagtc cgtgaagtga aggaagaact
     2461 gggtgtcaaa gctcaagctg ggcagctagc ttttgtggtt gaaaatcgtt ttgaacagga
     2521 cggtgtttcc tatcacaata tcgaatttca ttatctggta gacttactgg aggatgcccc
     2581 attgaccatg caggaagatg agaaaaggca gccctgtgag tggattgact tggataagct
     2641 tgaggatatc cagctagttc cagccttttt aaaaacggcc ctaccagatt ggaaaggcca
     2701 actaagacac atccatcttg agaaatagga gagaaatatg acatatcatt ttactgaaga
     2761 atacgatatt attgtaattg gtgcgggaca cgctggggtt gaggcttcct tggccgctag
     2821 ccgtatgggc tgtaaggtcc tgcttgcgac catcaatatt gaaatgctgg ctttcatgcc
     2881 ttgtaatccc tctatcggtg gttctgctaa ggggattgtc gtacgtgaag tcgatgccct
     2941 cggtggcgag atggccaaga ccattgacaa gacttacatc cagatgaaga tgctcaacac
     3001 agggaagggg ccagccgttc gtgcccttcg tgcgcaggct gacaaggaac tttactctaa
     3061 ggaaatgcgc aagacagttg aaaaccaaga aaatctgacc cttcgtcaaa ccatgattga
     3121 tgagattttg gtggaagatg gcaaggttgt cggtgtgcgt acagccaccc atcaagaata
     3181 tgctgctaag gctgttattg tgacgacagg gactgctctc cgtggggaaa ttatcatcgg
     3241 agacctcaag tactcatcag gtcctaacca cagcttggct tctattaacc tagctgataa
     3301 tctcaaggaa ctgggcctcg aaatcggtcg tttcaagaca ggaacccctc cacgtgtcaa
     3361 ggcttcttct atcaactacg acgtgacaga aatccaacca ggagatgaag cgcctaatca
     3421 cttctcatac acttcacgtg atgaggatta tgtcaaggac caagtgccat gctggttgac
     3481 ctacaccaat ggtaccagtc atgagattat ccaaaacaac ctccaccgtg cgcctatgtt
     3541 tacaggtgtg gtcaagggag tggggcctcg ttactgtccg tcgattgaag acaagattgt
     3601 gcgctttgcg gacaaggaac gtcaccaact cttccttgaa ccagaagggc gcaatactga
     3661 ggaagtctat gtgcaaggac tttcaaccag tctgcctgag gatgtccagc gtgacttggt
     3721 tcattccatc aaaggtttgg aaaatgcaga gatgatgcgg acaggttatg ctattgagta
     3781 tgatatggtc ttgcctcatc agttgcgtgc gactctggaa accaagaaaa tctcaggtct
     3841 cttcactgct ggtcagacaa atggaacgtc aggttacgaa gaggcagcag gccaagggat
     3901 tatcgcgggt atcaatgcgg ctctgaaaat ccaaggtaag cctgagttga ttttgaagcg
     3961 aagtgacggt tatatcgggg tgatgatcga cgacttggtg accaagggaa ccattgaacc
     4021 ttaccgtctc ttgaccagtc gtgctgaata tcgtctcatt cttcgccatg acaatgctga
     4081 tatgcgcttg actgagatgg gacgcgagat tggccttgtg gatgatgaac gctgggctcg
     4141 ttttgaaatc aagaaaaatc aatttgataa tgagatgaaa cgcctagaca gtatcaaact
     4201 caagccagtc aaggaaacca atgctaaggt tgaggaaatg ggcttcaagc ccttgacaga
     4261 tgcggtgaca gccaaggaat tccttcgccg tccagaagtt tcttaccaag atgtggtggc
     4321 cttcatcgga ccagctgcag aagacttgga tgacaagatt atcgaattga ttgaaacaga
     4381 aatcaagtac gaaggctata tttcaaaagc catggatcag gttgccaaga tgaaacgtat
     4441 ggaagaaaaa cgcattccag ccaatattga ctgggatgac attgactcta tcgcaacaga
     4501 agctcgtcag aagttcaaac tcatcaatcc agaaaccatc ggccaagcca gccgtatttc
     4561 gggagtaaac ccagcagata tttctatttt gatggtgtat ctggaaggta aaaatcgtag
     4621 tatttctaaa actcttcaaa aatcaaaatg atacgtcgtt ggcttcttac gaatgagttc
     4681 aaagcttggc tttgattcat ctccagcctc ccatagtttc ccgaactatg ggagctaact
     4741 caagttatgc attttcctag ccttctggtc tgattttcat tgagttttaa tctcaaaaga
     4801 aagcatagag aaaaacagct ccgaagacgg ggctgttttg ttgacttgta ctcaatgaaa
     4861 atcaaagagc aaactaggaa gctagccgta ggttgctcaa agcactgctt tgaggttgta
     4921 gatagaactg acgaagtcag ctcaaaacac agttttgagg ttgtggatag aattgacgaa
     4981 gtcagtaaca tatatacggc aaggcgaagc tgacgtggtt tgaagagtat tattcttcat
     5041 ctggtgtgag gatcatcggg atgatgatcg gttcacgttc ggtattttca tagaggaagg
     5101 ggcgaatagc gttgacaatg gcaccattga cagattgcac gctagcatcc ttatttttca
     5161 gtgcgatacg aatggcattg aagaggatac gctggctttg gcgaatcaag tcgccagact
     5221 ctctcatgta gacaaagcct cggctgagga tgtctggacc agatagaatc atctgcgatt
     5281 tgaagtcaac agttgcgact gccagaacga caccgtcttc agatagatcg cgacgatctt
     5341 tgaggacagc tgcgccaatt tcaccgatac gatttccatc gacatagata tcttgggcgt
     5401 tgaaatgacc tgcgatacga gctgagtcag cagtaagggc aagcacatcg ccattgctca
     5461 tgataaagat attgtccttc tcaacaccag tatccactgc tagtccagcg tggacttttt
     5521 gcatgcggta ttcaccgtgg acaggcatga agtattttgg cttaatcaag cagagcatga
     5581 gtttttgctc ttgctgacca ccgtgtccag atgtatggat attgttcact ttaccgtgga
     5641 taacttcgac accagcttca gaaatgatgt taatcagctt gttgacgcta gtagtgtttc
     5701 cagggatggg actagaagag aagataacgg tatcacctgg ttgtaattgt acttgacggt
     5761 gggttccgtt ggcgatacga gagagggctg ccataggctc accctgacta cctgtacaga
     5821 ggataagaac ttctcctgca ggataatctt tgatttcatt tggctcgata aaggttccct
     5881 taggagcttt gatgtagcca agatcgattc cgttgacaat ggccttttcc atagaacgac
     5941 caaagaccgc aatcttgcgt ccagtcttaa cagcagcttc tgttgcctgc tggagacgga
     6001 agatatttga ggcaaaggat gcaaagatga tacgtccttc aataccttgg ataatcttca
     6061 taatggactg accaacgact ttttcagagt tggtaaaggt tggtacttcc gcatttgtcg
     6121 agtcagacag gagacagagc acgccttctt caccaagcgc agccatacga tgcaagtccg
     6181 caggttctcc aactggagta aagtcgaact taaagtcacc cgtacagacg attttccctt
     6241 gaggagtatg aatgacaatc cccaaaggct ctggaataga gtgagtcgtt ctaaagaaag
     6301 ttgccttgag atttttaaag gtcaactcgg tgttgtggtt gatttcgtaa agtttggcgt
     6361 tgcgcaagag gccgtgttct tcgagtttcc cacggatcaa agccaaggca agcggtccag
     6421 cgtagatagg gacatttgct tgcttgagta ggaacggaat cccaccaatg tggtcctcgt
     6481 gtccgtgtgt gattaaaaca gccttgacgc ggtcgatatt gtccacgatg taagagtagt
     6541 caggaatgac atagtcgata ccaagcaagt catcttctgg gaatttaatc ccagcatcga
     6601 cgatgataat ctcgccttgg tattcaattc cgtaagtgtt tttcccgatt tctcctagac
     6661 caccgatggc aaaaacgccg acttcttcag gtttaagagt gtaggccata ttagaactcc
     6721 gtaatttcga aggcgccagt ttctttttcg taatcgagca atttgtcaga caagagttcg
     6781 atatattcga tattgtactc tgggcgattt tcttcgacaa gttggcgagc agtgatacgg
     6841 ccctcaagtt ctgagctggc atcgatgtct aggtaaagcg cgcgtgttgt ttcacggcgt
     6901 gggctacgtt cttttgtttc ttgataaaaa actttgtaaa tcatatagtt cctttctatt
     6961 tacaggtcag cttattccaa acttttagca gatatttgct tgatttcatt ccattttgtg
     7021 tctagattga ccttgattcg ttacaattat ttcaattata ccacaaaatg aaaaattagt
     7081 aaaagacgga aacgagaaag ttaggggacg atttcttcgg taagcgtttg cgaaaataaa
     7141 gaaaatgtat tatgttgata acggaagtga aatttattgc ttgtcataat tccatataga
     7201 ttttaagtca aggaggttgc cctatgtata acttatttgc ttttgctatc ggagttcgtt
     7261 tgctagcttt tatcgttttt gttttgcgtt tatggaggaa atcttctatt tgccaaactg
     7321 gaacgatgac aaaccaagtt cttgaggaaa attacctttg tgactctcta ctcgcttttt
     7381 ctcctcctcg tgacctatgt cgtttggttt gtattttact ttggattaaa tgcttagatg
     7441 ccctgcttat gctggggttt tttgtttggg gatgtagaga tagtagattt acgacacgaa
     7501 aattccaccc catctatcaa gatgaggtgg tctttgcatt tttctaaaat gatatgacaa
     7561 tggaattttc aaagcttatt atttttatgg gagtcattgt tctgctcaaa aatagagttg
     7621 aagcataaaa ataaaacaat acaaacagat aaatcgaatg gtaaagggat ggtagtaatg
     7681 ttcaaatcat tgagaatgct gagcaaactg taagagatga agacaataaa atttatcctt
     7741 ctaaaaatgt gtttcttatc tagcatgact taccaaactt tttacgaagg tcttttccaa
     7801 tggtataacc tgccataaat aaagcgatac caacacctac accaaagcca cccttgattt
     7861 cttgcaattc cttattagaa atttcacgac agttgttcaa atctttcatc atattaatct
     7921 cctcctaaaa aataaccagc tgccaaacca gaacctataa gtgctgttcc acctgcaata
     7981 gctttccaag atactgctac tccaaagata accaagggag cgagaccgcc atcaatatct
     8041 gataattcat tttcagataa ggataaaaat tgattgtcaa gaatgtcaaa atttgtcatt
     8101 gaactttcct ccttttttct tgttcacttt tatattcgga aaagaaaagg aaaagtgagc
     8161 atttttttaa attattttta gttaagtgag ggcactcttg tctgggggca aagaaaattc
     8221 ccatgtgcca gcttttgtag tataatagta agcagacaaa aagataggaa tgtgttatga
     8281 aagtattagc ttttgatacg tccagcaagg ctctttctct cgctatttta gaggacaagc
     8341 aggttcttgc cgagacgacg attaatatta agaaaaatca cagtattact cttatgcctg
     8401 ccatagattt tttgatggca agtttggatt ggacacccaa gaatttggac cgaatcgtgg
     8461 tagctgaagg gccgggtagc tacacaggct tgcgaattgc ggtagccact gccaagactt
     8521 tggctcatac tctgaacatc gagttagttg gtatgtctag cctcttggct ctggtaccct
     8581 accaacaaga aggcttgttc gtctctttga tggatgcgcg tcgcaacaat gtttatgtag
     8641 gattttatga aaatgctaaa cccgtcatgc cagaagctca cttacccttt gagcgagtga
     8701 ttgagttaat caagggtgct agtcaggtta cctttgtcgg agaagttggc ccctttgttg
     8761 agcagattca agaatacttg ccaaggacta atttcaaaga aaccttgcca aatgcagcta
     8821 atctagctct atgggcctgg gacaaggaag cagactcctt gcatgatttt gtgccgaatt
     8881 acctcaaacg agtcgaggct gaggaaaact ggctcaagaa ccataccgag tctggtgagt
     8941 cctacattaa acgcctatga tagaaatcaa gcgaattcaa caacagcctg acctagctca
     9001 agccatctac gctgttatag cagctgttta cctagtcagt ccttggactc tggagcaaat
     9061 ccaagcagat ctgtcccaag accagacttg gtatgcattg gcttatgatg gggcagaagt
     9121 gattggattt ctagctgtgc aggagaatct ttttgaagca gaagtcctgc aaatcgctgt
     9181 caaaggagcc tatcagggtc agggaattgc gtcagccttg tttgctcaat tgccgacaga
     9241 taaggagatt ttcctcgaag tcagaaagtc aaatcaacga gcgcaagcat tttacaagaa
     9301 agaaaaaatg gcggtcatcg ctgagcgaaa ggcctactac catgacccag tcgaggacgc
     9361 cattatcatg aagagagaaa tagatgaagg atagatatat tttagcattt gagacatcct
     9421 gtgatgagac cagtgtcgcc gtcttgaaaa acgacgatga gctcttgtcc aatgtcattg
     9481 ctagtcaaat tgagagtcac aaacgttttg gtggcgtagt gcccgaagta gccagtcgtc
     9541 accatgtcga ggtcattaca gcctgtatcg aggaggcatt ggcagaagca gggattaccg
     9601 aagaggacgt gacagctgtt gcggttacct acggaccagg cttggtcgga gccttgctag
     9661 ttggtttgtc agctgccaag gcctttgctt gggctcacgg acttccactg attcctgtta
     9721 atcacatggc tgggcacctc atggcagctc agagtgtgga gcctttggag tttcccttgc
     9781 tagccctctt ggtcagcggc ggacacacag agttggttta tgtttcggag gcaggagatt
     9841 ataagattgt tggggaaacc cgtgatgatg cggttggtga ggcttatgat aaggtcggcc
     9901 gtgtcatggg cttgacctat cctgcaggtc gtgagattga cgagctggct catcaggggc
     9961 aggatattta tgatttcccc cgtgccatga ttaaggaaga taatctggag ttctccttct
    10021 caggtttgaa atctgccttt atcaatcttt atcacaatgc cgagcaaaag ggagaaagcc
    10081 tgtctacaga agatttgtgt gcttccttcc aagcagcagt tatggacatt ctcatggcaa
    10141 aaaccaagaa ggctttggag aaatatcctg ttaaaaccct ggttgtggca ggtggtgtgg
    10201 cagccaataa aggtctcaga gaacgcctag cagccgaaat cacagatgtc aaggttatca
    10261 tcccccctct gcgactctgc ggagacaatg caggtatgat tgcctatgcc agcgtcagcg
    10321 agtggaacaa agaaaacttc gcaggctggg acctcaatgc caaaccaagt cttgcctttg
    10381 ataccatgga ataaagagtg gctctttgtc aagtgtagtg ggtaggcgaa aagctacaat
    10441 ctggagagta cgaaattcgt actctctttt ttgatgttca aagtcatcaa aatccgtttt
    10501 ttaaaattgt taaagttccg gaaaccaaag gctttgcgct tgataatctt aatcaaatta
    10561 ttggtcgctt caagtttagc gttggaataa ggcagcttaa gtgcgttgat aatcttatct
    10621 ctatccctta aaaaagtcca aaagaccgtt tgaaaaagcg gatgaaccgt tggcagttct
    10681 tgctcaatca atccaaagaa atggtcggca ttcttctctt gaaaatgaaa gagcaggagt
    10741 tgatagagtt cgtagtgaac ctgtaatccc tcagagtaag acagcagctt atctcgtact
    10801 tcccgatggg ttaagtgcat tcgaaacgtg ggctgataga atcgtttctg acagagcttg
    10861 aagctatact ggtgtagtaa atcagtccag tggactgatt tagcccgagc ctagaaacga
    10921 aaaagcgagg gttccaaaag cgcttgagcg cccgatactc caaggatttt cggtcaaatt
    10981 ggttcatgat ttggattcgt actcggttca tagctcggct cagatgttgg acaatgtgga
    11041 agcggtcaag aacaatcttc gcctttggaa agagttgctt agcgagccga taataagggc
    11101 tgtacatgtc catggtgatg acctcgacca gctcccgaac ctctctctga tagcgttgga
    11161 aatggtttcg aatcaccgca tgagttcgcc cgtctaaaat tgcgaggatg gatttggact
    11221 caaaatcttg ggcaatgaag ctcattttgc tctttttgaa gctatactca tcccaactca
    11281 taacttttgg caacttggtc caatcggttt caaacttaaa ttccctcagt tttcggatga
    11341 cggtggaagt tgagaccgcc aatctgtggg caatctcagt catagactgc ttttcaagga
    11401 ggagctgagc gattttttgt ctcaccatgt tggaaatctg gcaatttttc ttgacaatgg
    11461 atgtttgaga aacgaccacc ttaaggcaat tcttgcactg aaagcggcgc tttttgagat
    11521 gcagtaccgt gggtaaaccc tgacagtcga gaagcggaat tttagaggct ttctggaagt
    11581 cgtatttgat catcttccct tgacaatgag gacaaggagg agcgggggaa tccaactttg
    11641 cctgaacgac tagatgggtt tggtatttca gaacagacaa gattttgata tttttgtctt
    11701 ccaatccgag caaatctgtg gtattcttaa gttgttccat atgacccctt tctaatgagt
    11761 tggttagacg cttttcatta taggtcatat ggggcttttt ttctacaaga aacgacccta
    11821 taattcctgg ggtgggatta cccactacag aaattataga gccaaaacat tccaaagtat
    11881 tgtctgactc tggaatgttt tctgttcaca gttgttttgt aactgcctaa taagtaaccg
    11941 cgctataacg aggtatctac cgagattgtc aattctccag tatactgtta taaaaaacaa
    12001 aactggagga tttttttatg tccccccatc gtcccatcga ctgttccgta gctgcccaat
    12061 aacggagtat agtcggctga aacaagaata ggacaaaagt acctcaagaa aagcatcgta
    12121 atttgacaat attattctga gatgtttttg atgtaagccc atattttctc aatgggatta
    12181 tactcgggtg aataggtagg aagtggtagc agtctatgcc ctgctcctta cacatgttca
    12241 ttctgtgaaa ccttgcattg tccataatga taagggatgg tgtatctaaa gtaggtagta
    12301 agaatttttg gaagcaagct tcgaaaaagt cactcgtcat cgtatcttta taggtcatcg
    12361 gagccatagt atattgaaac aaaaaagggc attagtactt ctataacagt atcgcaatct
    12421 ctggtgtgcg ttgtctcgat cttaattcaa ataattatat cttcttccag agagactaac
    12481 tgcctgctca aggctcgatc atattcgaga taaaaatagg tctcaacccc tgtctcataa
    12541 atataaatag gagtcaggta gcttaagtga ttcaattctt taaggaaccg atttactttt
    12601 tctgggtctt gttcgcagta ggtacggctc ttttttagac tatatcccat agcctttaga
    12661 gcgtaatgaa tagttgttgg aggacagttg aattcagcag ctatttcagt caaataagca
    12721 tcgggatgag tttcaatata gatctttaat ttatctctat caactttttc aattaatagt
    12781 ggaagttttc ttaaagttag tgtgttgaaa cgtttttata cagtgctaaa atttgaagtg
    12841 tagtgcagat gtatttgtaa tagtattata gcaattcttt ggagaaggtc gagacaagag
    12901 aaaataggta tctttgagat ataagcatga tttactataa aattattgag ttattcataa
    12961 aaatttctct atcaaatatc ataatgcgtc gtttaaggag atggttacaa tgcaatatag
    13021 ttgtggaaaa ataaatatta atatccctga tggatatgga gacattaagg atatagtgtt
    13081 ttcggctcat attatagtta ggtataataa tggacattgt ggaggtatag atccgcatat
    13141 aattggactt tgtaaaaagc agatcagaag gatgtttcta tatcctattt tgataatcgt
    13201 atctagagat tcaaaggtta ttgatgatta taaaaattta gata
//
LOCUS       DAVLIK010000049        13108 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLIK010000049 DAVLIK010000000
VERSION     DAVLIK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13108
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.049"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..1010
                     /locus_tag="VXE87_001699"
                     /pseudo
     CDS             1..1010
                     /locus_tag="VXE87_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1094..2296)
                     /gene="rpsA"
                     /locus_tag="VXE87_001700"
     CDS             complement(1094..2296)
                     /gene="rpsA"
                     /locus_tag="VXE87_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0843209.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2458..2529)
                     /locus_tag="VXE87_001701"
     tRNA            complement(2458..2529)
                     /locus_tag="VXE87_001701"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2495..2497),aa:Gln,seq:ttg)
     gene            complement(2539..2619)
                     /locus_tag="VXE87_001702"
     tRNA            complement(2539..2619)
                     /locus_tag="VXE87_001702"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2583..2585),aa:Tyr,seq:gta)
     gene            complement(2669..2899)
                     /locus_tag="VXE87_001703"
     CDS             complement(2669..2899)
                     /locus_tag="VXE87_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0843210.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3067..3711)
                     /gene="pcp"
                     /locus_tag="VXE87_001704"
     CDS             complement(3067..3711)
                     /gene="pcp"
                     /locus_tag="VXE87_001704"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0843211.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3726..4649)
                     /locus_tag="VXE87_001705"
     CDS             complement(3726..4649)
                     /locus_tag="VXE87_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0843212.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4646..5335)
                     /locus_tag="VXE87_001706"
     CDS             complement(4646..5335)
                     /locus_tag="VXE87_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0843213.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5400..6104)
                     /locus_tag="VXE87_001707"
     CDS             complement(5400..6104)
                     /locus_tag="VXE87_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0843214.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKCGNVAPSQKDYDLNSTGWAPSYQDPASYLNIIDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDILTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(6160..7182)
                     /locus_tag="VXE87_001708"
     CDS             complement(6160..7182)
                     /locus_tag="VXE87_001708"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0843215.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7314..9785)
                     /gene="parC"
                     /locus_tag="VXE87_001709"
     CDS             complement(7314..9785)
                     /gene="parC"
                     /locus_tag="VXE87_001709"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0843216.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(10205..12148)
                     /gene="parE"
                     /locus_tag="VXE87_001710"
     CDS             complement(10205..12148)
                     /gene="parE"
                     /locus_tag="VXE87_001710"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0843217.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12284..12925
                     /gene="plsY"
                     /locus_tag="VXE87_001711"
     CDS             12284..12925
                     /gene="plsY"
                     /locus_tag="VXE87_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0843218.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(12959..>13108)
                     /locus_tag="VXE87_001712"
     CDS             complement(12959..>13108)
                     /locus_tag="VXE87_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843219.1"
                     /translation="NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKF
                     VLSQA"
BASE COUNT         3795 a         2943 c         2308 g         4062 t
ORIGIN      
        1 aaaatgatgg tcgctgaaac ttctatcgtc aagaagaatc accaaatccc tcgtatcatc
       61 aaccaaaaga ttgctcaaaa gttaattgaa aagatttcta tgactgatat tgcccatcag
      121 ctttccatct caacttcaac tgttattcgt aagctcaatg attttcactt taaacatgat
      181 ttttcttgtc ctcctgagat tatgtcctgg gacgttgaaa cagtccgggg agtgactgtt
      241 tcaatcggga gatggagatg agcttcattg cgcaagattt taacaatctc aatatcatca
      301 ctgttcttga gggtagaaca caagctatca tccgagatca ctttcttaaa tatgatagag
      361 ccgtccgatg tcgcgtcaaa atcattacta tggatatgtt tagtccttac tatgacttag
      421 ctagacaact tttcccgtgt gctaaaatcg ttcttgatcg ctttcacatt gtacaacatc
      481 ttagccgtgc tatgagtcgt gtgcatgtcc aaatcatgaa tcagtttcat cgaaaatccc
      541 atgaatacaa ggctatcaag cgctactgga aactcattca acaggatagc cgtaaactga
      601 gtgataagcg attttatcgt cctacttttc gtatgcactt aaccaataaa gagattttag
      661 acaagctttt gagctattca caaaacttga aacaccacta tcagctcttg ctttttcact
      721 tccagaataa ggaaccagag aaacttttcg gacttattga ggacaatctg aagcaggttc
      781 atcctatttt tcagactgtc tttaaaacct tcttcaaaga taaggaaaag attatcaacg
      841 cccttcaact acactattct aatgccaaac tggaagcgac caataatctc atcaaactta
      901 tcaagcgcaa tgcctttggt tttcgaaact ttgaaaattt caaaaaacgg atttttatcg
      961 ctttgaacat caaaaaagaa aggacgaaat ttgtcctttc tcgagcttag cttttttcaa
     1021 cccactacag ttgacaaaga gccgaaaaat cccttgttta gtaaacaaag gattttgtga
     1081 attttcaatt tgattaaagt tcgatatcac caaacaaatc agccattgaa aatcctgttt
     1141 gtgtttctgg aagttcgaaa tcacgctttt cttgacgtct tggacgacgt ggacgagcag
     1201 cacgtttttc ttctttttgt ccttcttctt gggctggacg ttcttcaaga gctttaatag
     1261 aaagtgatac gcgttctgca tctgcgttaa cttcaagaac tttaacttga acttcttgac
     1321 caactttaag agcttctttt ggattttcaa tccgtttgtg tgaaatttgt gatacgtgaa
     1381 caagtccatc gatacctggc aatacttcaa caaatgcacc gaagtcagtc aaacgtttaa
     1441 ctgttccttc tactacatca cctttagcca atttttgctc aacgccatcc catggtcctg
     1501 gtactgttgc tttaagtgaa agtgatacac gtccttcttc ttcgttaaga tcaaggattt
     1561 tcacttcaat ttcttcacca acagttacaa ctgattttgg tgatacgtta cgttcatgtg
     1621 acaattcagt caagtgaacc aatccgtcaa caccaccaag gtcgatgaaa gcgccgaagc
     1681 ttgtgatacg agcaacttta ccagttacaa catcaccaac agccaattta ccgaatactt
     1741 cagcgcgagc tgctgcagta gctgcttcaa caacttcacg acgtgaaagg atgaagcggt
     1801 tttctttagc gttaacttct ttgattttag tatcaaattc ttgacctaca aaacgctcag
     1861 cgttacgtac gaaacgagta tccaacattg aagctgggat aaatccacga acaccttcaa
     1921 attctactga aagtccacct ttaacggcac gcgttccttt aacagtaaca acttcttctt
     1981 cgcgaccaac aagtttgtcc catgctttgc gagcttcaag gcgtttttta gatacaaggt
     2041 atgtaactgt atcagtatct ttaccaacta cttgacgaag tacaagaaca tccaatactt
     2101 ctcctacttt aacaaagtca ttgatatctg catcacgatc gtttgtcaat tcgcgaagag
     2161 tcaagacacc ttcaacacca gttccagaga ttgcaacgtt agcttgagtc gcatcaactg
     2221 tcaatacttc agcactaaca acatcaccag tctcaacttg actaacgcta tttagcaaat
     2281 cttcaaattc gttcatctaa aaaatcctcc aacaatcaag tttttcttaa acttgacata
     2341 cttataattt ttttcctaag cacccgcaag gacatgttca tatcattcac gtctttcaat
     2401 tataaaaata aaatacccta agatattttg ctttttatct tgattattac ctaagaactg
     2461 gggtagctgg attcgaacca acgcatgagg gagtcaaagt cccttgcctt accgcttggc
     2521 tataccccat taatgaaatg gagagagagg gattcgaacc cccgaacccg aaggagcgga
     2581 tttacagtcc gccgcgttta gcctcttcgc tatctctcct acaatcaaca tggactatta
     2641 tatcatgaaa atttcaaaaa aacaagactt attttgctaa attataattt tcaatcaaaa
     2701 tttccacagc tttttccaat tttttataaa aactatcgac attcccattc tttataatgg
     2761 caaattgtcc gtctaattcg gcaatttctc cgataacttt tttaccgata gtcaatgtat
     2821 aaccttcaaa actgtcttta ccaacattaa ctttggcatc cgctacttga atttcgattt
     2881 ttttatcttt cttgctcatt tcatacctct cttcactttt tctattttac aagaaaatcc
     2941 taaaactagc aagaaaaaac tctatatcag gcttctctga tatagagttt tatgtaaaca
     3001 acctcaatcg atttagcata gctaatagtt agtaaacaag cataattgac tatcctttct
     3061 aggttatcag tgagtctcac cgcctactaa ctgcaaatcc ttatctttgt agtctacaat
     3121 agcttcaata gctacctcta tgcctcttac aatatcacat agactcattc ctgcagtatt
     3181 cggcttattt actacttgtt ccatcatata tggaatatgc atgaaacctg ctctcatatt
     3241 agggaatttt ttatccacta aataaagagc ttggtacatc aaatgattgc aaacaaaggt
     3301 tcctgcacta ttggatacaa ctgccggaag tccctgtttt ttgatagctt gtaccatcgc
     3361 tttgataggt aaactactaa aataggccga tgctccatca atacgaatcg gtgtatcaat
     3421 tggttgattg ccttcgttat caggtatgcg agcatcatct tgattaatag ccactcgttc
     3481 aggtgttaag ccggtcctgc cgcctgcttg tccaatacaa agtacagcat ctggttgata
     3541 tcgtaatatt tctgcctcta aaacttctga cgacttataa aaaaccgttg gaatttctac
     3601 ccagcgaact tcagccccat taatctcaga tggtaataat tttacagcct ccaaagctgg
     3661 attaatcttt tcacctccaa aaggattaaa acctgtaacc aatattttca ttttattttc
     3721 ctttactaaa atgcgagaaa gtacattaag aatatgtgaa taacaatcat tactagagca
     3781 acacctgctt gagcctttat aacgccattc tgatctttca tatccatcaa tgctgctggt
     3841 agagcgttaa aattagcagc cattggggtc aataaggtcc cacaataacc tgctgtcatg
     3901 gcaagagcac cagccacaat tggattagct cccagagcaa atacaaaggg aactccaaca
     3961 cctgctgtaa taacggtgaa tgctgcaaaa gcatttccca taatcattgt gaatagaacc
     4021 attccaagaa cataggccaa aactcctata aagcgactat ctgaaggaac aataccgcta
     4081 atcagatgag agataacatc accaacacct gctacagtaa aaatagcccc caaagcccct
     4141 aataattgag gaacaatacc acttgttgaa acttgctgag tcattcgatt attttctgat
     4201 aacagactct tagggtgact attggtaatc acaagaacag aaattgtagc aaacaaggcg
     4261 gcaaggctaa tcgaaatctt gctaaattct ggaatcattt gcgctaagac caacgcaagt
     4321 attgccatca gcataactgg aataaaaatt ttatttttca acctgttaga ttcaatattg
     4381 gctttcattt catctaagga tggcaaggtt ccgatacgga cttgcttaaa caatgttaac
     4441 agcgataata ggattacaat aataccaata ctcatatttg gcatatagga accacctata
     4501 aacgtaatag acaatagagt ccaaaatgca gatgtcccaa gtcgaactgg gtttgtttta
     4561 tctttataac tacaataggc tgtatggaga aattgacaac caatcacaat ataggtcaac
     4621 tctaatagtt gctttgccaa ctctgtcatt tttgttctcc tcccctagtc ttttttgata
     4681 tcaatttttt atcaaataaa taattgtaaa tccccactac aataagtgtt ataacagcaa
     4741 caataataga tgtagaagca atccctgcat aattgctttc atagcctaac tgatctaatg
     4801 ttccccctat caagaggact cccccagcac ctacaaacgt attttgagca aagaaatttc
     4861 caaaattttc attcgcagcc gcacgcgctt ttattgtctc atcttcaacc tctgttaact
     4921 ttctacctaa ttgagactct gcagctgctt ctcccatagg ttgaaccaaa ggtctgacaa
     4981 actgagggtg tcctcctaga cgaattgaaa agaaaccagc taactctcga ataaagaaat
     5041 aaactgtata gaagtttcca actgtcagac ctttaatctt tcgaatcaaa tcgattgatc
     5101 gttgcttgag tccaaaggtt tctgacagcc ccacaagagg caaggtaacc ataaaaatcg
     5161 tgagcactcg ctgattgcta aattcttttc ccaaaatctc caaaaattca acgagagaaa
     5221 cacctgaaac taaagctgta accaaaccag ctaagactac tgttgcaatt gtatcaaatt
     5281 ttaaaataaa acccacaaca atgattgcta ttcctattaa tctaatccac tccatatcaa
     5341 actcctttat attcaaaatg acagtatttt taaaatttta tcaagatcaa taccattcct
     5401 tatttaatgt gtttttctag ttctttttgg tatttgctat tggattccaa tttttctttt
     5461 tgccattttt taaaaacctc gttatattct tttgttgtaa gaatatcttt ttgcaatttc
     5521 attcctttaa agatatatgg atccccctta ataccaactt gtgagtatgg ttttgagaat
     5581 ggtactacgt tacttacaac tggagaacca ccagatgaag ctgttggcat caataatgaa
     5641 ctatctgtcg accaagcttg agctttggca tatttttcat atcttttctc taggtcagtg
     5701 gtctcagaaa cagcatcttc taacaatttc ttatatttat ccaaaccagg tttagctaca
     5761 acatccttat cttttccttt cgtaatacca aggtgtttca tggcagaacc agattttgga
     5821 tctataatat tcaagtaaga cgctggatct tgatagcttg gagcccatcc tgtactattc
     5881 aaatcatagt ctttttgaga aggagcaaca ttgccgcatt tatcattttc catcaaacca
     5941 tcaataacat ttccaataac gtctgtcgtc gatgttcgag tcgctatact gtagcccaat
     6001 gatgctggat ctactgcata gacataagaa aatgttgtcg gtgcatctgc ttctttatca
     6061 gtttttccac aagccactaa aatagctgac gtgctcagga ccactcctgc tgttaagagc
     6121 cactttttct atttcataaa aaatctcctt tggtttattt taatctactt ttacaatcca
     6181 accttctggc gcttcaatat cgccaaactg aatacccgtc aattcattat ataatttacg
     6241 cgtcacagga cctacttctg tttcactata gaatacatgg aaatcatcac catgttgaat
     6301 acctccaatt ggagaaataa ccgctgctgt accacaggca cctgcctcta caaaacggtc
     6361 aagattatca attggaacat caccctcaat aggagttaat cccaagcgat gttctgccaa
     6421 ataaagcaag gaatacttgg taatagatgg caagatagat ggactcaatg gtgttacaaa
     6481 ttcattatca gctgtaattc caaagaagtt agctgatccg acttcttcaa tctttgtatg
     6541 agttgatggg tccagataga taacatctga gaaatgacgt gacttggcca tttttcctgg
     6601 taagagactt gcagcatagt ttccaccaac cttagccgca cctgtaccat ttggtgctgc
     6661 acggtcgtac tcatcctgaa tcaagaagtt ggttgggacc aaaccacctt taaagtaatt
     6721 tccaactggc atagcaaaga tggtgaaaat gtattcttct gccggtttta ccccgataat
     6781 atctccgaca ccaatcaaaa gagggcgaag atataaggtt ccacctattc cgtatggtgg
     6841 tacgtattct tcattcgcac ggacaactgc tttacaagct tctacaaaca tgtctgtcgg
     6901 aacttgtggc atcaagagac ggtcacatgt acgttgcagg cgtttagcat tttcatcagg
     6961 acggaacagt tgaacactgc catccttagt acgataagct ttcaaacctt caaatgcttg
     7021 ttgtccatag tgaagacttg gagaagactc tgaaatatgc aaagttgcat cctctgtaag
     7081 ctctccttga tcccattgtc catttttgaa atgagcaaga tagcgataag gtaatttcat
     7141 ataggaaaaa ccgaggtttt cccaatcaat cgttactgtc atattccact ccttattcta
     7201 aaaacctatt tcttatattc tacactattt ttctaaaata gcaagtatat tttgtaattt
     7261 tcagaaaatt tctccaataa aaaccagctc ttagaactga ttcttcattt cacttattta
     7321 tcttcagtaa ctacttcctg aagataagcg tcaaaaactt cttcatctga aatcgtgtca
     7381 gaaatgaagc ttccattgct agtgcgttct gacaagttca agtcttgcaa tcggctttca
     7441 tagattgttc ctttattgga ttggacaagc agagtttggt cgttcacatc cacttccgta
     7501 ctgaagaaat cgccaacaaa tccttgctct gcaactgctc ctgccaagaa gacacgatgc
     7561 ggtttgtttt tcaactcacg caagacttgt aatcctcgtt tggcacggct ggttgctaga
     7621 atttcctcaa tggaaacacg tttcaagctt ccacgctggg tcaagaggta gaaggacgaa
     7681 gtattacaga taaagccaga ttggaggaca tcatcttctt tcaaattcat agccttgaca
     7741 cctgctgcct tagcaccgac aaccggaacc tcttcgatat tgaaacgcag ggcataacca
     7801 ttttgactaa ccaagacaac atcatctagt ttaatcggag ccactgctac aatctgatct
     7861 gtatcgtctt tgagcttagc atacttgaca gacttagatc tataggtccg ccatggagta
     7921 aattcttttc gctctacccg tttgatttga ccaaggcgag tcgctgcaaa gtaggttgtc
     7981 gcatcgtcaa actgatccag tacttccaca taaagaattt cttcattcgt ttcaaagttt
     8041 gtgatggttt ggctcagatg ctctccgatg tccttccaac gaatatctgc caactcatgg
     8101 attggtctgt agatgacatt tccaagactt gtgaacatca agaggtgctg ggttgtcttg
     8161 gcagattgaa caaaaatcaa acggtcatca tcacgcttgc caatttcttc caaggtggaa
     8221 gccgcaaagg aacgtggact ggtacgcttg atgtaacctg ccttggtcac gctgacgtag
     8281 gtatcttcct cagcgataag actagctgta tcaatctcaa ttgctttcgc agtatcttct
     8341 aaagaactca aacgaggagt tgcaaatttc ttcttgacct cacgaagttc tttcttcatg
     8401 agattgtaca tagtcctttc atcaccgata atagccgcca gcatagcaat cttctcacga
     8461 agctctgctt cttcttcctg caagacaacc acatcggtat tggtcaaacg gtacagttgc
     8521 aaagttacga tagcctcagc ctgttcttcc gtaaaatcat agctaacttt gaggttttcc
     8581 ttggcgtccg ccttattctc agaagcacgg ataagagcaa tgacttcatc caaaatcgaa
     8641 atcacacgaa tcaaaccttc gacgatatgg agacgtttct cagccttttc tttgtcaaag
     8701 cgtgaacgcg ccaaaatcac ttctcgacgg tgagcgatgt agctagacag gattggaaca
     8761 atcccaacct gacgaggtgt gaaattgtca atcgccacca tattaaagtt gtagttgatt
     8821 tgtaggtcgg tgtacttaaa taagtagttg agaacaagct cagtattagc gtctttctta
     8881 agttcgatag cgatacgaag accatcacgg tcagactcat cacgaacctc agcaatccca
     8941 gctaccttgt tattaacacg aacatcatcg attttcttga ctagattggc cttattgatt
     9001 tcataaggaa tctcagtaat aacgatttgt tccttaccac cttttagctt ttcaatttca
     9061 gtcttggaac gaacaaccac gcgccctttc ccagtctcat aagctttctt gatttcatca
     9121 cgaccctgaa taatagcccc tgtagggaag tctggtccag gcaagaattc catgagttta
     9181 tcaatctttg cagttgggtg gtcaatcatg taaactgcag catctatgac ctcagctaaa
     9241 ttatggggag gaatgtctgt ggcataacca gccgaaatcc cagtcgaacc attgaccaag
     9301 aggtttggaa aggctgctgg caagaccgtt ggttctttct ccgtatcgtc aaagttccat
     9361 gcaaaaggaa ctgtattttt ctcgatatcc tgaagaaggt agcctgcaat ttcagacaaa
     9421 cgtgcctcag tataacgcat agccgcagga ggatctccgt ccatagaacc gttattaccg
     9481 tgcatttcaa ctagaatctc acgatttttc cagttctgtg acatacgaac catggcatca
     9541 tagatagaag aatccccgtg tgggtggaaa ttccccatga tgttcccgac tgacttggcc
     9601 gacttacggt agctcttgtc aaaagtattg ctatccttat tcatagaata aagaatacgg
     9661 cgctgaaccg gcttcaaccc atcacgaata tctggcaaag cccggtcttg aataatgtac
     9721 ttggagtagc gaccaaagcg ctctcccatg atgtcctcca gggacatgtt ttgaatgtta
     9781 gacataagat acaaagccca taaaatacca agtgaaaata gaaaattctt gaagtaagca
     9841 aactcacaag agaatttatc tttttcacac agtatctagg gcgtgttcaa ctcctttcaa
     9901 agaatgtaga gtaggttttt atgcagtaaa agatatttta cgggaattcg tcccgtgttc
     9961 agttacgata agtaaccaaa ctatcctgtt tgtatttttc aatatgaaaa tctggttttc
    10021 caaaattagt cttagtttgt gtcttagccg ctcccttaaa cgcctctttg agataagcac
    10081 tcatagaaga ttcttcatta ataatcctgc aattttttca aaccaagatt ttcaaactgc
    10141 ttttttacat agtcattcac atccgactct aatttccagt ttactaacat attattttct
    10201 ttcattaaaa cactgtcgct tcttctagcg taaacttgac attatcttca atccatttac
    10261 ggcgtggttc taccttatct cccatgagaa cattgacgcg gcgttcggcg cgcgctaaat
    10321 cttcaattgt gacacggatg agggtacgtg tttctgggtt catggttgtt tcccagagct
    10381 ggtccgcatt catctcacca agtcctttgt atcgttggag ggtagcgcct ttaccgaact
    10441 gtttacggag ttcttctagt tctccgtccg tccaagcgta ggccacttct tctttcttgc
    10501 ctttaccttt ggacatcttg taaagaggtg ggagggcaat atagacatga cctgcctcga
    10561 ctagcggacg catgtaacgg tagaaaaatg tcaagagcaa ggtctggata tgggcaccgt
    10621 cggtatccgc atcggtcatg ataatgatct tatcatagtt ggcatcttca atagagaagt
    10681 ctgctccaac acccgcacca atggtataaa tcatggtatt gatctcttca tttttgagga
    10741 tatccgccat cttggccttg gctgtattga caaccttacc acgaagaggt agaatagcct
    10801 ggaacttgcg gtcacgacct tgtttggcag aaccaccggc agagtccccc tcaactagat
    10861 agagttcatt cttagcagga ttcttagatt gggctggggt caatttccca gacaacaagc
    10921 ccttatcttt cttgtttttc ttcccatttc ggctctcatc acgcgcctta cgtgctgctt
    10981 cacgagcatc acgggccttg atagccttgc ggatgaggtt agaagctaat tccccatttt
    11041 ccataaggaa aaaggtcaac ttatcagcca ctattccatc cacaactggg cgagctaggg
    11101 ggcttcctag tttatccttg gtctgtcctt caaactgcaa gtgttcttca ggaactaaga
    11161 tagaaagaac ggccgctagt ccctcacgat agtctgaacc ttcaaggttt ttatcttttt
    11221 ccttgagaag acctgtttta cgtgcatagt cattcatgac cttggtaatg gcagacttga
    11281 gtcctgtctc gtgcgttcca ccgtccttgg tgcgaacgtt attgacaaag gatagaatgt
    11341 tatctgagaa tccgtcattg tactggaggg ctacttccac ttgaaaacca ttgtcttccc
    11401 cttcaaagta aagaactggc gtcaagattt ccttatcttc gttgagataa gaaacaaaat
    11461 cttgtactcc attctcatag tggaactcaa tcgcttcatc tgttcgcttg tccgttaaag
    11521 acaaggtcac atttttcaag agaaaggctg attcattaag gcgctctgaa atggtattgt
    11581 acttgaaatc tgtcgtagaa aagatagtcg cgtcaggcat aaaagtaact ttggtgcctg
    11641 ttttagactt gggtgctgta ccgattttct tcaaagtcgt gacaggtttt ccaccatttt
    11701 cgaaacgttg cttgtaaact gcgccatcac gggtaatttc aacttctaac cagctagaaa
    11761 gggcgttaac aacggaagaa cccactccgt gaagtccacc tgatgtctta tagccacctt
    11821 gaccgaattt ccctccggca tgaagaatgg taaagataac ctcaacagtt ggaattccca
    11881 tagcgtgcat acctgtcggc atcccacgtc catggtcttg aaccgttaga ctaccgtctt
    11941 tattgatagt tacatcgata cgatcaccaa acccagacaa ggcttcatcg actgcattat
    12001 caacgatttc ccaaactagg tgatgaagac cagcgccatc ggtcgatcca atatacatcc
    12061 ccggacgttt tcggaccgca tccaaccctt ctagcacctg aatagcatca tcattataat
    12121 tgttaatatt gatttccttt tttgacacaa ggaacctcct attcgttcat ctttactatt
    12181 ctacaggttt tccaaggatt ttgcaaaatt tttctttctc cgatgtgaca atttcagcag
    12241 agattctctg cttttctttc ccaattcatg atataatagg agtatgatta caatagtttt
    12301 attaatccta gcctatctgc tgggttcgat tccatctggt ctctggattg gacaagtatt
    12361 ctttcaaatc aatctacgcg agcatggttc tggtaacact ggaacgacca ataccttccg
    12421 cattttaggt aagaaagctg gtatggcaac ctttgtgatt gactttttca aaggaaccct
    12481 agcaacgctg cttccgatta tttttcatct acaaggcgtt tctcctctca tctttggact
    12541 tttggctgtt atcggccata ccttccctat ctttgcagga tttaaaggtg gtaaggctgt
    12601 cgcaaccagt gctggagtga ttttcggatt tgcgcctatc ttctgtctct accttgcgat
    12661 tatcttcttt ggagctctct atcttggcag tatgatttca ctgtctagtg tcacagcatc
    12721 gatcgcggct gttatcgggg ttctgctctt tccacttttt ggttttatcc tgagtaacta
    12781 tgactctctc ttcatcgcta ttatcttagc acttgctagt ttgattatca ttcgtcataa
    12841 ggacaatata gctcgtatca aaaataaaac tgaaaatttg gtcccttggg gattgaacct
    12901 aactcatcaa gatcctaaaa aataggctct ttgtcaactg tagtgggttg aaaaaaagct
    12961 aagcttgaga aaggacaaat tttgtccttt cttttttgat attcagagcg ataaaaatcc
    13021 gttttttgaa gttttcaaag tttcgaaaac caaaggcatt gcgtttgata agtttgatga
    13081 gattattggt cgcttccaat ttggcgtt
//
LOCUS       DAVLIK010000050        12458 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLIK010000050 DAVLIK010000000
VERSION     DAVLIK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12458
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.050"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..626
                     /locus_tag="VXE87_001713"
                     /pseudo
     CDS             1..626
                     /locus_tag="VXE87_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            818..3109
                     /gene="pcrA"
                     /locus_tag="VXE87_001714"
     CDS             818..3109
                     /gene="pcrA"
                     /locus_tag="VXE87_001714"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0843220.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYCADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVAEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASIEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            3152..3832
                     /gene="radC"
                     /locus_tag="VXE87_001715"
     CDS             3152..3832
                     /gene="radC"
                     /locus_tag="VXE87_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0843221.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3829..4518)
                     /locus_tag="VXE87_001716"
     CDS             complement(3829..4518)
                     /locus_tag="VXE87_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0843222.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4536..5177)
                     /locus_tag="VXE87_001717"
     CDS             complement(4536..5177)
                     /locus_tag="VXE87_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0843223.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(5260..5475)
                     /locus_tag="VXE87_001718"
     CDS             complement(5260..5475)
                     /locus_tag="VXE87_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0843224.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5483..5830)
                     /locus_tag="VXE87_001719"
     CDS             complement(5483..5830)
                     /locus_tag="VXE87_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0843225.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5835..6950)
                     /locus_tag="VXE87_001720"
     CDS             complement(5835..6950)
                     /locus_tag="VXE87_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0843226.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6960..7919)
                     /locus_tag="VXE87_001721"
     CDS             complement(6960..7919)
                     /locus_tag="VXE87_001721"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0843227.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(8032..8601)
                     /locus_tag="VXE87_001722"
     CDS             complement(8032..8601)
                     /locus_tag="VXE87_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0843228.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8729..9400
                     /locus_tag="VXE87_001723"
     CDS             8729..9400
                     /locus_tag="VXE87_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0843229.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            9384..10202
                     /locus_tag="VXE87_001724"
     CDS             9384..10202
                     /locus_tag="VXE87_001724"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0843230.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            10199..11095
                     /locus_tag="VXE87_001725"
     CDS             10199..11095
                     /locus_tag="VXE87_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0843231.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            11139..12113
                     /gene="pta"
                     /locus_tag="VXE87_001726"
     CDS             11139..12113
                     /gene="pta"
                     /locus_tag="VXE87_001726"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0843232.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3660 a         2384 c         2671 g         3743 t
ORIGIN      
        1 tatgtgtgag aataccgcac ttatgaagaa attgcggctg atcttggtat tcacgaaagc
       61 aacttactcc gtcggagcca atgggttgaa gtaactcttg ttcaaagtgg tgttacgatt
      121 tcaaaaactc atcttagtgc tgaggatacg gtgattgtgg atgcaacaga ggtaaaaata
      181 aatcgtccta aaaaaatcaa ctagccaatc attctggtaa aaagaaattt cacgctatga
      241 aggctcaagc gattgtcaca agtcaaggga gaattgtttc tttggatatc actgtgaact
      301 attgccacga tatgaagttg ttcaaaatga gtcgcagaaa tatcggacaa actggtaaaa
      361 ccttggctga cagtaattat caagggctca tgaagatata tcctcaagca caaactccac
      421 gtaaatccag caaactcaaa ccgctaacag ttaaagataa agcctataac catgcgttat
      481 ctaaggagag aagcaaggtt gagagcatcc ttgccaaagt aaaaacgttt aaaatgtttt
      541 caacaaccta tcgaaatcat cgtaaacgct tcggattacg aacgaatttg attgctggca
      601 ttatcaatca tgaactagga ttctagtttt gcaggaagtc tattgaggta ttgagctagt
      661 ttatgaaaaa attgggtgaa aaagtcgagt gttttagaaa cccacagtgt agtattctag
      721 tttcaatcca ctatattttg ctactccccg taaagtttct attttccctg atttctgata
      781 taatagaaat attgacttca agagtaagga agagaagatg aacgcattat taaatggaat
      841 gaatgaccgt caggctgagg cggtgcaaac gacagaaggt cccttgctaa tcatggcagg
      901 agctggttct ggaaagactc gtgttttaac ccaccgtatc gcttatttga ttgatgaaaa
      961 gctggtcaat ccttggaata tcttggccat tacctttacc aacaaggctg cgcgtgagat
     1021 gaaagagcgt gcttatagcc tcaatccagc tactcaggac tgtctgattg cgaccttcca
     1081 ctccatgtgt gtgcgtattt tgcgtcgcga tgcggaccat attggctaca atcgtaattt
     1141 tacaattgtg gatcctggtg aacagcgaac gctcatgaaa cgtattctca aacagttgaa
     1201 cttggatcct aaaaaatgga atgaacgaac tattttgggg accatttcca atgctaagaa
     1261 tgatttgatt gatgatgttg cttatgctgc ccaagctggc gatatgtata cgcaaattgt
     1321 ggcccagtgt tatacaacct atcaaaaaga acttcgtcag tctgaatccg ttgactttga
     1381 tgatttgatt atgctgacct tgcgtctctt tgatcaaaat cctgatgttt tgacctacta
     1441 ccagcaaaaa ttccaataca tccacgttga tgagtaccaa gataccaacc acgctcagta
     1501 ccaattggtc aaactcttgg cttcccgttt taaaaatatc tgtgtggttg gggatgcgga
     1561 ccagtctatc tacggttggc gtggtgctga tatgcagaat atcttggact ttgaaaagga
     1621 ttaccccaaa gccaaggttg ttttgttgga agaaaattat cgctcaacca aaaccattct
     1681 ccaagcggcc aacgaggtta ttaaaaacaa taaaaatcgc cgtcctaaaa atctctggac
     1741 tcaaaacgct gatggggagc aaatcgttta ctattgtgcc gatgatgagc tggatgaggc
     1801 tgtatttgta gccagaacca tcgatgaact tagtcgcagt caaaacttcc ttcataagga
     1861 ttttgcagtt ctctatcgga ctaatgccca gtcccgtaca attgaggaag ccctgctcaa
     1921 gtctaacatt ccttatacca tggttggcgg aaccaaattc tacagccgta aggaaattcg
     1981 cgatattatt gcttatctca accttattgc taatttgagt gacaatatta gttttgagcg
     2041 tattatcaac gagcctaaac gtggaattgg tccaggtaca gttgagaaaa tccgtgattt
     2101 tgcaaatttg caaaatatgt ctatgctgga tgcttctgct aatattatgt tgtctggtat
     2161 caagggtaag gcagcccaat ctatctggga ttttgccaat atgatgcttg atttgcggga
     2221 gcagctagac cacttaagca ttacagagtt ggttgagtcc gtcctagaaa aaacaggtta
     2281 tgtcgatatt cttaacgccc aagcgactct agaaagcaag gctcgggttg aaaatatcga
     2341 agagtttctt tctgttacga agaactttga tgacaccact gatgtggcag aagaggaaac
     2401 tggtctggac aaactgagtc gtttcttaaa tgacttggct ttgattgccg acacagattc
     2461 aggtagtcag gagacatcag aagtgacctt gatgaccctg catgctgcta aaggtctcga
     2521 atttccagtt gtctttttga ttgggatgga agaaaatgtc tttccactta gtcgtgcgac
     2581 tgaagatcca gatgaattag aagaagagcg ccgtctagcc tatgtaggta tcacgcgtgc
     2641 agagaaaatt ctctatctga ccaatgccaa ctcacgcttg ctttttggtc gtaccaatta
     2701 taaccgtccg actcgtttta ttaacgaaat cagttcagac ttgcttgagt atcaaggtct
     2761 ggctcgtcct gcaaatacaa gctttaaggc atcatatagc agtggtagta tttcctttgg
     2821 tcaaggtatg agtttggctc aggctcttca agaccgtaaa cgcggtgctg ccccaaaatc
     2881 aatccagtca agcggtcttc catttggtca atttacagct ggcgcaaaat cagcatctat
     2941 cgaggcaaat tggtccattg gtgacattgc tctccacaag aaatggggag agggaaccgt
     3001 tctggaagtt tcaggtagcg gtgctaggca ggaattgaaa atcaatttcc cagaagtagg
     3061 tttgaaaaaa cttttagcca gtgtggctcc aattgagaaa aaaatctaat tttccatcct
     3121 tctcacgaat aataaagtga ggaggatttt tatgtacagt atttcattcc aagaagattc
     3181 actattacca agagaaaggc tggccaagga aggagttgaa gcgcttagta accaagagtt
     3241 gctagctatt ttactcagga caggaacacg tcaagctagc gtttttgaaa ttgcccaaaa
     3301 agtcttgaac aatctttcaa gcctaacgga tttgaaaaaa atgaccctgc aggaattgca
     3361 gagtttgtct ggtattgggc gtgttaaggc catagaatta caagctatga ttgaactggg
     3421 gcatcgtatt cacaaacacg agactcttga aatggaaagt attctcagca gtcaaaagtt
     3481 ggccaagaag atgcagcagg aattagggga taaaaaacaa gagcacctgg tggcactcta
     3541 tctcaatact caaaatcaaa tcatccatca gcagaccatt tttatcggtt ctgtaactcg
     3601 tagtatcgct gaaccgcgag agattcttca ctatgcaatc aagcacatgg cgacttctct
     3661 tatcttggtc cacaatcatc cttcaggagc ggtagcgcct agccaaaatg atgatcatgt
     3721 cactaaactt gttaaagaag cctgcgaact gatggggatt gttctcttgg accatttgat
     3781 tgtctctcat tctaattact ttagttatcg tgaaaagaca gatttaatct aaagttcatt
     3841 aacgacatag tcaaagagtt tcttatcttt gggacgattt tcaaaaagaa gttctggatg
     3901 ccattggaca ccgagaaagg cgacatcatc cgtactcatg acagcctcaa tgataccatc
     3961 tttaggatca tgagccacaa cttttaaatt tggtgctaag tccttgatgc tctggtggtg
     4021 gaaggagttg atatgagaga tttctccata gatttcttgg agaacggtat ctggttctgt
     4081 caccaagcgt tgagttgtgt actcaacaga agaatcctgc caatggtctt cgatatcttg
     4141 gtacaaagtt ccacccatgg caacgttaaa gagttgggta ccacggcaga cagagaaaat
     4201 gggctttttc tgtttaatag cttccttgat gagggccagt tcgaagatat ctctttgaag
     4261 gtgataatca tcgctatcaa tggttttggg ttcgccatag aattttggat cgacattttg
     4321 cccacctgtc aagatgagct tgtcaatcaa actgatatag tggcaggcca tttcttgatc
     4381 accaatcggt aggatgatag gaatccctcc agcatcttta acgccttcaa caaagccttt
     4441 tgctgcgtag ctcatcatga tgtcatcatc tggatgagtt ttttcgtttc ctgtaatccc
     4501 aataactggt tttttcataa aatgattttc gctttctaat cctcttttcg catgaagtag
     4561 aggagggttt ggagttcact tgtcaaatcg acatactgaa cgaccacgtc ttttggtaaa
     4621 tgcagatgga ctggtgaaaa actgagaatt cctttcacac cagcatcaac caagagatta
     4681 gcaacctctt gtgacttgac gctgggaaca gttaggatag cagtcttcac atcagcatcc
     4741 ttgattttat ccttgatctg agaaatcccg taaatgggaa tcccgtcagg agtttgggta
     4801 ccgacttcag gatggtcgtc taggtcaaag gccatgataa tcttcatctt gttacgttcg
     4861 tggaagcggt agtggagaag ggcatggccc atatttccaa taccaaccag catgacattg
     4921 gtaatagagt tgtcattgag caaatcggca aaaaatgtca ttagtttttt gacatcatag
     4981 ccaaaaccac gacgaccaag ttcaccaaaa taggaaaaat cacgacgtac ggtcgctgaa
     5041 tcaatcccaa tggcctctgc aatttgctta gagttggcac gttcaatctt ttctgcatga
     5101 aatctcttaa aaattcgata gtagagagag agtctttttg ctgtagcttt tggaatagca
     5161 aactgtttat ctttcacaaa atcacaacct ttctattctt ctattttata gaaacattgt
     5221 gaaaaaatca acaaaaataa gaaaaaacta agaaaaatct tagttttgat gtaaaaaatc
     5281 tgcatgagat agaaaacggt agaggtctcc gaccagcccc tgataaactt ttttgcccct
     5341 aaaagtcaga gaagtcacat aaagtgtatc tggtaaggtt acacatcctg acaaagtcaa
     5401 catgagagcc tcatgatcct catacttgag agtacgctct acatgatagc agtccttata
     5461 ggtcagttca aacattttgg ctctatcttt ccgattttgt aaagacacca cgttctacca
     5521 agctatccat gaggaagtag aatttttcct gatgaatatg gtggtcttct gatttgaaaa
     5581 tatcaactag acgaaggcca aacttgtcag tgatattgat tttagcccct gtaagttcct
     5641 tgttaatgat gattttgagt tggaagcctt caccgctgtt tggcactttt tccaaaaggc
     5701 gagtcagttc atagttacca accttagttt caaaaaaggt gttatctttg agggtgaatt
     5761 ttttaacaga agggctaaga gtgtaatcgt aacgacaatt ttttaactga atgatttttt
     5821 caaatgccat atggctaacc tccgataatt tcttttaagg tttttgcgag ggtttgtagg
     5881 tcttcaacgg tattttgtgg cgacaaactg atgcgaaggg attccttcaa gcgttctgaa
     5941 tttgcgccat acatggcttc aagaacatgg ctggattgga caacgcctgc agtacaggct
     6001 gagccagtag agattgaaat tccagctaaa tctagccgaa ggagtaagag gtcatttttc
     6061 tgaccaggaa atccaatatt gagaacataa gggagatgat gttttcctct attcaagtaa
     6121 tactgaatgc cctccagctc tgccagaaag gcagtttcta gattttgtac atgttgaaaa
     6181 tgttcttctt gtttttctag gtcttctttt agggctgcaa ccatgcctac gatagcaggc
     6241 agattttcag ttcctgcacg ttttttctgt tcctggtctc cgccatgtag ataggaatca
     6301 aagtccatgc tagatgcgta gagaaaaccg attcccttag gaccatggaa tttgtgggca
     6361 gaagcagtga gaaaatcaat gcccaattct tctgaatgaa ttgggatttt accaatagcc
     6421 tgaactgcat caacatgata ggcagcaggg tgttgcttga gtatttggcc aatttcagcg
     6481 atgggcagta ggtttcctgt ctcattattg gcaaacatgg tagaaaccaa aatcgtatcg
     6541 tcacgtaaag ccttttgaat ttgctgggct gtgatttctt gattttctgg ctggataatg
     6601 gttgcttcaa acccaaagtg ttgaaccaag taatcaattg tttcaaggac agcatggtgc
     6661 tcgatggcag ttgtgatgat atgttttcct tgttcttggt gacgaagaca gtagccaatg
     6721 atggtagtat tattgccttc agtcccacca gaagtgaaaa agatatgttg aggttttgtc
     6781 cttagtaact gggctagttc ctgacgggct tctcgcaaga gtttgccagc ttgacgacca
     6841 tgaccatgaa tactagaagg atttccgtgg gtttcttgca taaccttggt catagctgaa
     6901 atagcaactg ctgacatagg agtcgttgca gcattgtcca aataaatcaa agaatcacct
     6961 tatttctttt tattgtaggc aaagagtggg ctgactggtt ttctttcgtg aatacggacg
     7021 atagcatcac caattaactc actagcagtg atgtagcata catttttagg agttttttct
     7081 tttgttgcta ctgaatcagt cacaagaatt tctttaatat tagtattgtc aagaagctca
     7141 gcagctccct cgacgaagag accgtggcta gaaacagcat aaatttctgt agctccttca
     7201 cgttcaacga ttttagaagc ttcagagaag gtacgtcctg tatttaaaat atcatcaatc
     7261 aagatagctt tcttaccttc aacatcacca ataatataac cttcgttacg agttgcatcg
     7321 tcttgagggt agtcgataat ggcgatagga gcatcaagat attcagccag gctacgcgca
     7381 cgtttgacac ctgaattttt agggctaacg acaacaacat ctgaaccaag caatccttta
     7441 tcgcagtaat gttttgcgaa taggggaaca gtgaaaagat tatccactgg aatatcaaag
     7501 aaaccttgaa cctgaacggc atgcaaatca agagtcagga tacgatcaac tccagcctta
     7561 accagcatat tggcaactag ttttgctgta agtggctcac gaggacaagc aatgcggtct
     7621 tgacgtgcat agccaaaata tggaaggaca acgttgatac tgtgggcact tgcacgcaca
     7681 caagcatcga ccatgattaa caattccatt aggtggttgt tgacagggaa acttgttgat
     7741 tggatgatgt aaacatcata accacggaca ctttcttcga tatttacttg gatttctccg
     7801 tctgaaaatt gacgtgatga tagttttcca agtgggacac caacagcttg ggcaattttt
     7861 tgtgcaatct cttggttaga gttgagtgcg aaaagtttca tgttttttct atctgacatt
     7921 atagaccgtc ctctgtaaac tttataaatc ctagttatat ttaccttaca tatatgaact
     7981 gggatttgtg tatttttatc ttttctattt taccaaaaaa tggagattat ttcagctatt
     8041 tttcatactt ttgacaaatc gaaccaattt tgaaggagct ttttggtagg aaatctgatt
     8101 tttctctaaa aattgtcgga aatcctgttt gccttgctca tgattttcca cttcaagctc
     8161 caattcgtaa tctgttatat caaagtatcg gctctgatcc agtgccatga gaccaatagc
     8221 tgttttcatt tcatagcgaa gcgttgttag acaaccaaga acctgccagt tcttactttg
     8281 gataccatgt ttcgccaatt catccagtac tagcccttga ggaagttctt ccttactcag
     8341 atagttctca gcatctttta gttgtaattt ttggttgtat tccatgtttc caacactctg
     8401 cgggactttg agtgtcaatt cagcccagtc ttcaaaggtt cgaatgcgca tagcgacttt
     8461 cttttctcgc agttcaaaat caggcgtgtc gatgtagtaa tttgtttgaa gaacaggagt
     8521 gacacctgtg aactggtctt ttagacgatt gtattcatct tttttcaata gtgttttcaa
     8581 ttcaatttct aaatgtttca tttttcttac ctttttttat cgttgaaagc ggatttatgg
     8641 tataataagc attgtattta ttgtatatga atctggagaa aaaatcaaag atatttttga
     8701 cggataatat gagaacaagg gagaatatat gaccttagaa tgggaagaat ttctagatcc
     8761 ttacattcaa gctgttggtg agttaaagat taaacttcgt ggtattcgta agcaatatcg
     8821 taagcaaaat aagcattctc caattgagtt tgtgaccggt cgagttaagc caattgagag
     8881 catcaaagaa aaaatggctc gtcgtggcat tacttatgcg accttggaac acgatttgca
     8941 ggatattgct ggcttacgtg tgatggttca gtttgtagat gacgtcaagg aagtagtgga
     9001 tattttgcac aagcgtcagg atatgcgaat catacaggag cgagattaca ttactcatag
     9061 aaaagcatca ggctatcgtt cctatcatgt ggtagtagaa tatacggttg ataccatcaa
     9121 tggagctaag actattttgg cagaaattca aattcgtact ttggccatga atttctgggc
     9181 aacgatagaa cattctctca actacaagta ccaaggggat ttcccagatg agattaagaa
     9241 gcgactggaa attacagcta gaatcgccca tcagttggat gaagaaatgg gtgaaattcg
     9301 tgatgatatc caagaagccc aggcactttt tgatcctttg agtagaaaat taaatgacgg
     9361 tgtaggaaac agtgacgata cagatgaaga atacaggtaa acgaattgat ctgatagcca
     9421 atagaaaacc gcagagtcaa agggttttgt atgaattgcg agatcgtttg aagagaaatc
     9481 agtttatact caatgatacc aatccggata ttgtcatttc cattggcggg gatggtatgc
     9541 tcttgtcggc ctttcataag tacgaaaatc agcttgacaa ggtccgcttt atcggtcttc
     9601 atactggaca tttgggcttc tatacagatt atcgtgattt tgagttggac aagctagtga
     9661 ctaatttgca gctagatact ggggcaaggg tttcttaccc tgttctgaat gtgaaggtct
     9721 ttcttgaaaa tggtgaagtt aagattttca gagcactcaa cgaagccagc atccgcaggt
     9781 ctgatcgaac catggtggca gatattgtaa taaatggtgt tccctttgaa cgttttcgtg
     9841 gagacgggct aacagtttcg acaccgactg gtagtactgc ctataacaag tctcttggcg
     9901 gtgctgtttt acaccctacc attgaagctt tgcaattaac ggaaattgcc agccttaata
     9961 atcgtgttta tcgaacactg ggctcttcca ttattgtgcc taagaaggat aagattgaac
    10021 ttattccaac aagaaacgat tatcatacta tttcggttga caatagcgtt tattctttcc
    10081 gtaatattga gcgtattgag tatcaaatcg accatcataa gattcacttt gtcgcgactc
    10141 ctagccatac cagtttctgg aaccgtgtta aggatgcctt tatcggtgag gtggatgaat
    10201 gaggtttgaa tttatcgcag atgaacatgt caaggttaag accttcttaa aaaagcacga
    10261 ggtttctaag ggattgctgg ctaagattaa gtttcgaggt ggagctattc tggtcaataa
    10321 tcaaccgcaa aatgcaacgt atctattgga cgttggagac tacgttacca tttacattcc
    10381 cgctgaggaa ggctttgaaa ccttggaggc tattgagctt ccattagata ttctctatga
    10441 ggatgaccac tttctagtct tgaataaacc ctatggagtg gcttctattc ctagtgtcaa
    10501 tcactctaat accattgcca attttatcaa gggttactat gtcaagcaaa attatgaaaa
    10561 tcagcaggtt cacattgtta ccagactaga tagggacact tctggcttga tgctctttgc
    10621 caagcacggt tatgcccatg cacgattaga caagcagttg cagaagaaat ctatcgagaa
    10681 acgctacttt gctttggtta agggagatgg acatttggag ccagaagggg aaattattgc
    10741 tccgattgcg cgtgatgaag attccattat taccagacga gtggctaaag gcggaaagta
    10801 tgcccatact tcatacaaga ttgtagcttc ttatggaaat attcacttgg tctatattca
    10861 cctgcacact ggtcgaaccc atcaaatccg agtccatttt tctcatatcg gttttccttt
    10921 gctgggagat gatttgtatg gtggtagtct ggaagatggt attcaacgtc aggctctgca
    10981 ttgccattac ctatcctttt atcatccatt tttagagcaa gacttgcagt tagaaagtcc
    11041 cttgccggat gatttcagta accttattac ccagttatca actaatactc tataaaaact
    11101 gtctcagagt ataattatta tcttaaagga gaaaactcat ggaagttttt gaaagtctca
    11161 aagccaacct tgttggtaaa aatgctcgta tcgttctccc tgaaggggaa gagcctcgta
    11221 ttcttcaagc aacaaaacgc ttagtaaaag aaacagaagt gattcctgtt ttgcttggaa
    11281 atcctgaaaa aattaaaatt tatcttgaaa ttgaaggaat catggatggt tatgaggtca
    11341 tcgaccctca acattatcct caatttgaag aaatggtttc tgccttggtg gagcgtcgca
    11401 agggcaaaat gactgaagaa gatgtacgca aggttttggt tgaagatgtc aactactttg
    11461 gtgtgatgtt ggtttacttg ggcttggttg atggaatggt gtcaggagcg attcactcaa
    11521 cagcttcaac agttcgccca gctctacaaa tcatcaaaac tcgtccaaat gtaactcgta
    11581 cttcaggagc cttcctcatg gttcgtggta cggaacgtta cctatttgga gactgtgcca
    11641 ttaatatcaa tccagatgca gaagccttgg ctgaaattgc catcaactca gcaatcacag
    11701 ctaagatgtt tggcatcgaa cctaaaattg ccatgttgag ctattctact aaaggttcag
    11761 ggtttggtga aagcgttgat aaggtcgttg aagcaactaa aattgctcac gacttgcgtc
    11821 ctgaccttga aatcgatggt gagttgcaat ttgatgcggc ctttgttccc gaaactgcag
    11881 ctctgaaagc tccgggaagt acagtagctg gtcaagcaaa tgtcttcatc ttcccaggta
    11941 tcgaggcagg aaatatcggt tacaagatgg ctgaacgcct gggtggcttt gcggctgtag
    12001 gacctgtttt gcaaggttta aacaagccag ttaatgatct ttctcgtgga tgtaatgcag
    12061 atgatgttta caagttgacc ctcatcacag cagctcaagc agttcatcaa tagtgaaaac
    12121 tataaagtga tatactatgc tatactgtag ttatgaaact atgtacgaaa agcactgcca
    12181 ttaattcctg agaactaaat tactgattgg tgtcaaaaag gaaaacttcc aagcgatgat
    12241 atcctgtcta tacacgacct atagaaatct gtaatataca tatccgtaaa acgataaatt
    12301 ccctttttga ttttaaatga gtatgaaaag agaatttttt ggctctttgt caactgtagt
    12361 gggttgaaga aaagctaagc tcgagaaagg acaaatttcg tcctttcttt tttgatgttc
    12421 aaagcgataa aaatctgttt tttgaagttt tcaaagtt
//
LOCUS       DAVLIK010000051        12368 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLIK010000051 DAVLIK010000000
VERSION     DAVLIK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12368
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.051"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            147..302
                     /locus_tag="VXE87_001727"
                     /pseudo
     CDS             147..302
                     /locus_tag="VXE87_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            502..3777
                     /gene="rexB"
                     /locus_tag="VXE87_001728"
     CDS             502..3777
                     /gene="rexB"
                     /locus_tag="VXE87_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0843233.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFFEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3774..7424
                     /gene="addA"
                     /locus_tag="VXE87_001729"
     CDS             3774..7424
                     /gene="addA"
                     /locus_tag="VXE87_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0843234.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7639..8817
                     /locus_tag="VXE87_001730"
     CDS             7639..8817
                     /locus_tag="VXE87_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843235.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9026..>12368
                     /locus_tag="VXE87_001731"
     CDS             9026..>12368
                     /locus_tag="VXE87_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0843236.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSESEVSNQKSSVATSTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPAVQPELPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYTRPQAGAVVEPAIQPELPEAVVTDKGEPAV
                     QPELPEAVVTDKGETEVQPESPDTVVSDKGEPKQVAPLPEYTGPQASAIVEPEQVAPL
                     PEYTGVQAGSIVEPEKVEAPKEYTGKIEQPSAEDTKPENEASSTNGESERPKDKIKEE
                     KQVDKKLELRNVSNVELYTVENNKYRHITAVDGALDSSLKYFMKVKSENFKDIMLPVT
                     KIESTTKNNKEVYKIVAHAENLIQHENNVISNDYTYYLPKTQQSETGVYTSFKNLVDA
                     MNSDPNGTFHLGATMDAREVELPDDQESYVKNEFYGKLIGENNGKYYAIYNLKKPLFK
                     TLNTATIQNLSIKEANVSSKEDAATISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKV
                     DNSRISNSSFTGRITNTYDTTVGYEIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQ
                     IVGGIAGVVEKSATIKYSYVEGNVNNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVL
                     SDVNVTNGNAISGDNFDNMKEDHAYSSKGNKVVNVVQVDDELVTKDSDVQRGTVLDAD
                     KVKEKKAELVSKHSTKVEDFDFTSRYTTIYNEVTGYQKSREQVYKNIEKLLPFYNRET
                     IVKYGNLVDESSELFTKELLSVVPMK"
BASE COUNT         4067 a         2381 c         2591 g         3329 t
ORIGIN      
        1 ctatttttgg ttcattttac tatagtagat tgaaataaga tacgaacagc ttgattaggg
       61 aaatcaaatt aatttctaga aatattttag catccacggt gtactgttat agtttcaatt
      121 tactatagtt caatcattct atcaagaata ttgaatatat aaaggcacgt aatattaaaa
      181 cttcttctga tatcgaatta gagtccgatg ttgatggcga taaatcagac aatctacccg
      241 tcgacattaa gatactggga caacacattg aagtgtattc cgtacctaag aaacaatcat
      301 aaaactcaaa gccttgttac cgaggctttt ttattatgtg attttcagta gccagactta
      361 ttctatctaa tacaagtaaa gctaagtatt taagatttag cagatgatga agaaaagaaa
      421 ggatggccta aatattttaa cagatttacg aggctaatca tggtataata tagggtgatg
      481 aaaaattcca acgaggctga gatgaaatta ctttatactg atattcggac ttctttgaca
      541 gaaattctaa caagagaggc agaagagcta gttgcagctg gcaagcgggt cttctacatt
      601 gcccccaact ctctttcttt tgaaaaggaa cgcgccgtgc tggaatactt gtcccagcag
      661 gcttcttttt cgattaccgt cacgcgcttt gctcaaatgg ctcgctatct ggtcttgaat
      721 gatttaccag ctaaaactac tcttgatgat atcggtcttg ggttggcctt ttacaaatgc
      781 cttgccgaac tcgatcccaa ggacttgcgt gtttatggcg ctattaagca ggatcctcaa
      841 ttgatccagc agttaattga gctttaccat gagatgacca aatctcagat gagttttttg
      901 gacttggaga atttaacaga tgaggataag agggcggatt tactcttgat ttttgagaaa
      961 gtaacagcct atcttaatca aggtcagtta gcccagggaa gtcagttgtc ccatttgatt
     1021 gaggctattg agaatgacaa ggtaagtagt gattttaatc aaatcgcctt ggtcattgac
     1081 ggctttactc gtttttctgc tgaggaagag cgggttgtgg acttacttca cggcaaaggt
     1141 gttgagattg ttatcggggc ttatgctagt aagaaagcct ataccagtcc ttttagcgag
     1201 ggcaatctct accaagccag cgtaaaattt ctccatcatc tggcttctaa ataccaaacg
     1261 cctgctcagg actgttctca aactcatgag aagatggata gttttgacaa ggcctctcgt
     1321 ttgttggagt cttcttatga cttttcagaa ctcgctttgg atgtcgatga gaaagaccgt
     1381 gaaaatttac aaatctggtc ttgtttgacg caaaaggagg agttggagct agtagcccgt
     1441 agtattcgtc agaaattaca tgagaactca gacctgagct acaagcattt tcgtattctc
     1501 ttgggggatg tagcttctta ccagttatct ctcaaaacca tttttgacca gtatcagatt
     1561 cctttttatc ttggtagaag cgaagccatg gctcatcatc ccttgactca gtttgtcgag
     1621 tctattttag ctttaaaacg ttaccgtttt cgtcaggagg atttgattaa tcttcttaga
     1681 actgatttgt atactgacct cagtcagtct gatattgatg cttttgagca atatatccgc
     1741 tatcttggta tcaatggctt gccagccttt cagcaaacct tcaccaaatc ccaccatgga
     1801 aaatttaatc ttgagcgttt gaatgtcctc cgcctgagaa ttttagcacc tcttgaaacc
     1861 ctctttgcca gccgaaaaca aaaggctgaa aacctcctac aaaaatggag tgtctttcta
     1921 aaagaaggag ctgtgaccaa gcagttacaa gatttgacaa ccactttgga agctgtagaa
     1981 caggaaagac aagccgaagt ttggaaggct ttctgccatg ttttagaaca atttgcgact
     2041 gtttttgctg gttcacaggt tagtctggaa gacttcctag ccttgctcca ttctggaatg
     2101 agtttgtccc aataccgtac cattccagca acagtggaca ctgttctggt gcagagttac
     2161 gatttgattg caccattgac tgctgacttt gtctatgcta ttggactaac tcaggacaat
     2221 ttaccaaaaa tttctcaaaa caccagtctt ctgacagatg aagaaaggca aaatctaaac
     2281 caagcgaccg aagaaggcgt tcaattactg attgccagca gtgaaaatct caagaaaaat
     2341 cgctacacta tgctttcctt ggtcaattct gctcgtaagc agttgttctt gtcggctcca
     2401 agccttttta acgaaagtga aagtaaggaa tctgcctatc ttcaagagtt gatccatttt
     2461 ggatttaggc ggagagagaa gaggatgaat cacaaaggac tgtctaagga ggatatgggg
     2521 tcctatcaca gtcttttgtc tagtctggtt gcctatcacc agcagggtga gatgagcgat
     2581 actgagcaag atttgacttt tgtcaaggtt ctgtcgcgtg tcataggtaa aaaactagat
     2641 cagcaaggtc tggaaaatcc agccatccca atcagtccaa gcagcaagac cttagccaag
     2701 gacaccttgc aagctctcta tcctgccaaa caggagtttt acctgtctac gtcgggtttg
     2761 acagagtttt atcgcaatga atacagttat ttcctacgct acgttttagg cttgcaggag
     2821 gaattacgtt tgcgtcctga tgcccgtagt cacgggaatt tcttgcatcg tatctttgaa
     2881 cgcgccttgc agttgcctaa tgaagattcc tttgaccaac gtctagaaca agctattcaa
     2941 gaaaccagtc aagaacgcga atttgaagct atttatcaag aaagtttgga agcccagttt
     3001 accaaggaag ttttgcttga tgttgcacgg acaactggac atattctccg acacaatcca
     3061 gccatcgaaa ccatcaaaga agaagcaaat tttggtggaa aagaccaagc ctttattcaa
     3121 ttagacaatg gacgcagtgt ctttgtacga ggcaaggtgg accggattga ccgtttgaaa
     3181 gctaatggag cgataggagt agtagactac aaatccagtc tgactcagtt ccagtttcct
     3241 catttcttta atgggctcaa ttctcagtta ccaacctatc ttgctgccct aaaaagagaa
     3301 ggggagcaga actttttcgg cgccatgtac ttggaaatgg ctgaacctgt ccaatctctg
     3361 atggcggtaa aaagtctggc aggagcagtg gtagaagcca gcaaatctat gaaataccaa
     3421 gggctcttct ttgaaaaaga aagcagttat ttaggcgaat tttataacaa aaacaaggct
     3481 aatcaactga cagatgagga atttcagctc ctactggact acaatgccta tctttacaag
     3541 aaagctgctg agaagatttt agcaggccgg ttcgccatca atccttatac tgaaaatggc
     3601 agaagcattg ccccatacgt ccagcaacat caggctatta caggctttga agccaattac
     3661 catctgggcc aagcccgttt cctagaaaag ttggacctag ctgatggcaa gcgtctggtc
     3721 ggagaaaaac tcaagcaagc ttggcttgaa aaaataagag aggagttgaa tcgatgaagc
     3781 ttattccctt tttaagtgag gaggagattc aaaaactgca agaagcagaa gcaaattcga
     3841 gcaaggaaca gaagaaaact gccgagcaaa tcgaagctat ctacacttct ggccagaata
     3901 tcctggtctc agcatcggct ggttctggaa agacctttgt catggcagag cgcattctgg
     3961 accaattggc gcgtggtgtc gaaatttctc aactctttat ctcaaccttt accgtcaagg
     4021 ctgcaactga acttaaagaa cgtttagaga aaaaaatcag caagaaaatc caagaaacag
     4081 atgatgtcga tctcaaacaa cacttgggtt gccagttggc agacctaccc aacgctgcca
     4141 tcggaaccat ggactctttc acacaaaaat tccttggcaa acatggttat ctgcttgata
     4201 ttgcacctaa tttccgtatt ttacaaaacc aaagcgagca acttcttctc gaaaacgaag
     4261 tctttcatga ggtctttgaa gcgcattacc aaggtaaaca gaaagagagc tttagtcatt
     4321 tgctgaaaaa ctttgctggg cgtggcaagg acgaacgggg tctgcgccag caagtctata
     4381 aaatctatga cttcctccaa tccaccagta atcctcaaaa gtggctgagt gaatctttcc
     4441 tcaaaggctt tgagaaagct gattttacca gtgaaaaaga aaaactgact gagcaaatca
     4501 aacaagccct ctgggatttg gaaagctttt tccgttacca tctggataac gatgccaagg
     4561 agtttgcaaa ggctgcctat ttagaaaatg ttcaattaat tctggatgaa attggctccc
     4621 taaatcagga gttcgatagt caggcttatc aggcagtgct tgcgcgtgtt gtcgccatct
     4681 ctaaggagaa aaacggtcga gctctgacta atgccagccg taaggctgat ttgaagcccc
     4741 tggctgatgc ctacaacgaa gagagaaaga cccagtttac taaactagga caattatcag
     4801 accagataac cattctcgac tatcaagaac gttatcatgg agacacttgg aaactagcta
     4861 aaaccttcca atctttcatg agcgattttg tagaggctta tcgtcagaga aaacgacagg
     4921 aaaatgcctt tgaattcgct gatatcagcc attacaccat tgagatttta gaaaatttcc
     4981 cacaagttcg tgagtcttat caggagcgct tccatgaagt catggtcgat gagtatcagg
     5041 ataccaacca tattcaagaa cggatgctgg aattgttgtc taatggccac aatcgcttta
     5101 tggtgggaga tatcaagcaa tccatctatc gtttccgtca ggcagacccg cagattttca
     5161 atgagaaatt ccaacgctat gcgcaaaatc ctcaagaagg caagctcatt ctcctcaagg
     5221 aaaatttccg tagtagttca gaagtgctgt cagcaaccaa tgatgtcttt gaacgtctca
     5281 tggaccaaga ggtcggcgaa atcaactatg ataacatgca ccagcttgtt tttgccaata
     5341 ccaaactgac tcccaatcca gacaacaagg ccgaatttct cctctacgac aaggacgata
     5401 caggtgagga agaagagagt caaacagaaa cgaaactaac aggcgaaatg cgcttagtta
     5461 tcaaggagat ccttaaactt catcaggaaa aaggtgttgc ctttaaggaa attgcccttc
     5521 tgacctctag tcgtaatcgt aatgaccaaa ttctacttgc cctgtctgag tacgggattc
     5581 ctgtcaaaac tgacggagag caaaacaatt atctccaatc cctagaagtg caagtcatgc
     5641 tagacactct tcgtgtcatt cacaatcccc tgcaagacta cgccttggtt gcccttatga
     5701 agtctccaat gtttggtttt gatgaggatg agctagcacg tttgtccctt cagaaagcag
     5761 aggataaagc ccacgaaaat ctctatgaga aactggtcaa tgcacaaaaa aaggcaagta
     5821 gtcaaaaagg cttgattcac acagctctag ctgaaaaact aaagcaattc atggatatcc
     5881 tagcttcttg gcgcttgtat gccaaacccc actctctcta tgacttgatt tggaagattt
     5941 acaacgaccg tttttattat gactatgttg gggctttgcc gaatggtcct gctaggcagg
     6001 ccaatctcta tgccctagca ctgcgtgctg atcaatttga aaagagcaat ttcaaaggtt
     6061 tgtcgcgttt tattcgtatg attgaccaag tcttagaagc ccagcacgat ttggcaagcg
     6121 tggccgtcgc accgccaaaa gatgcagtag agctcatgac catccacaag agtaaagggc
     6181 tggagtttcc ttacgtcttt atcctcaata tggatcaaga tttcaacaag caggactcta
     6241 tgtcagaagt cattctcagt cgtcagaatg gtcttggtgt caaatatatt gccaagatgg
     6301 agacaggggc agtagaagac cactatccta aaaccatcaa actctccatt cctagtctga
     6361 cctataggca gaacgaagag gaattacagc tagcaagcta ttctgagcag atgcgtttgc
     6421 tgtatgttgc tatgacgcgg gctgagaaaa agctctatct tgtcggcaag ggttctcgtg
     6481 aaaagctgga agctaagcaa tacccagcag ccaaaaatgg gaaactaaat agcaatacta
     6541 gactgcaagc acggaatttc caagattggc tttgggctat cagtaaagtg tttactaagg
     6601 acaagctcaa ctttagttat cgttttattg gcgaagatca gttgaccaga gaagctatcg
     6661 gagagttgga aaccaagagt cctctccaag atagctccca agcagacaat cgtcagtcag
     6721 ataccatcaa agaagctctg gaaatgctga aggaggtgga agtttataat actcttcacc
     6781 gcgcagctat tgaacttcct agtgttcaaa ccccaagtca aatcaagaaa ttctacgaac
     6841 cagttatgga tatggaaggt gtcgagattg ctggtcaagg tcagtcagta ggcaagaaaa
     6901 tcagcttcga tttgccagat ttttcaacca aagaaaaggt aactggagct gagattggta
     6961 gtgctactca cgaactcatg cagataattg acctcagcca gcaactaacc cttgctagcc
     7021 taacagaaac actcaaacaa gttcaaacta gccaagctgt cagagacaag atcaatcttg
     7081 ataaaattct tgctttcttt gacacagcac tcggtcagga aattcttgct aataccgacc
     7141 atctctatcg cgagcaacct ttctccatgc tcaaacgaga ccaaaagagt caggaagact
     7201 ttgttgtccg tggtatcctt gatggctatc tgctttacga aaacaaaatt gttctgttcg
     7261 actacaagac agaccgctat gatgaaccaa gtcaactcgt agaccgctat cgtggtcagt
     7321 tagctctata cgaagaggct ttatcacgag cctattcgat tgaaaatatt gaaaaatact
     7381 tgattttact cggtaaagac gaggttcaag ttgtaaaagt ataacttata ctcttcgaaa
     7441 atctcttcaa accacgtcag cttcgccttg ctgtatatat ggttactgac ttcgtcagtt
     7501 ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc tacaacctca
     7561 aaacagtgtt ttgagctgac tgcggctagc tttctagttt gctctttgat ttttattgag
     7621 tattagaaag gagacctcat gacacttcca gttagaaaat ccctgcacga tgcagtttta
     7681 caggcttcga aagcggatac ttgggaacaa gctaccaagg aatggaatga agtttccttg
     7741 atttttaacg gtattggccg tagcaattgt gtctgtggaa atgccatcaa atacgcttat
     7801 gaactcttta acggtgtcac aggccaacgc ctctttccaa ttggtagcga ctgtgttcgt
     7861 cattttcatc gattgtccct tgaccagcaa ttggaagagg aagaaaaact gctcagaaag
     7921 gttgaaaatc taaccagaaa agctcagaaa aaggaaaaaa tcaaggtcaa taaaagtgac
     7981 tttgacgagc gacttctaaa atggctctgg gaaaaaggtg ttttcaaacc caatcgtggc
     8041 aatcaatttg cgcctgagag agactaccag cttttcctag aagtctttca gggaggaagt
     8101 tggaccaagg cggaaccaaa gaaaaaggct cggatggaag aagtccttga aaagtgtatc
     8161 aaaccctttt tacttgggaa atcggatgac caactctacc ttgtcaagct aggcaaggag
     8221 aaaattgact acgaacaaga actccgtatc caggcagaga aagaacgtaa gaagagggat
     8281 aaaatcgcca agcaatatgc agacaatctg gttctagcca tgggacccgc agagcgtgct
     8341 tatcaagatt actttggctt tacagagacc ctgactcaag aagaacgcaa gtgggaaaaa
     8401 attctttttg gtaaaaatag agcagaacgg gctatcaagg ccaaacaata ccaaaaagag
     8461 ctggaaaaag accaacgaat tgccagtcag gatccaattg aaagaaaaca gaagcagact
     8521 tggctcctca attcctattt tcgtgagctt cctgaagaaa aagctcgatt ttctaggctc
     8581 ttattagaat atcgaaaaaa tggtgaagta cccttttcaa ctgaatacct gtcagatcat
     8641 ctcatcgact ttttctataa aatgaaagcc tttgaatttg aaatcgcacc agaacaagtc
     8701 cgagattttc taaaaaaaag cctgcaggaa gaccatcgct catcagcaca aggaagctgg
     8761 atagaaggaa ttctcctcaa ctgcctcaaa ccatttttag aacgattagt gatatgagta
     8821 acacctaccg tgtaaatttc atggtaggtg ttattgtacc cccaaataat ataaaacaaa
     8881 gtatgaaagc gcatctcaat tttaagactt ttttgtaaat taagagtata attaaggtat
     8941 actgcctttt ctatagataa tagataatac actaatataa taaaggtctt tgtaacatat
     9001 ataaatttta tttcaaggag gaataatgga aaagtatttt ggtgaaaaac aagagcgttt
     9061 ttcatttaga aaattatcag taggacttgt atctgcaacg atttcaagtt tattttttat
     9121 gtctgtatta gctagttcat ctgtggatgc tcaagaaact gcgggagttc actataaata
     9181 tgtggcagat tcagagctat catcagaaga aaagaagcag cttgtctatg atattccgac
     9241 atacgtggag aatgatgatg aaacttatta tcttgtttat aagttaaatt ctcaaaatca
     9301 actggcggaa ttaccaaata ctggaagcaa gaatgagagg caagccctag ttgctggtgc
     9361 tagcttagct gctctgggaa ttttaatttt tgctgtttcc aagaaaaagg ttaagaataa
     9421 aacggtatta catttagtat tggttgcagg aataggaaat ggtgtcttag tttcagtcca
     9481 tgctttagaa aatcatcttt tgctaaatta caatacggac tatgaattga cctctggaga
     9541 aaaattacct cttcctaaag agatttcagg ttacacttat attggatata tcaaagaggg
     9601 aaaaacgact tctgagtctg aagtaagtaa tcaaaagagt tcagttgcca cttctacaaa
     9661 acaacaaaag gtggattata atgttacacc aaattttgta gaccatccat caacagtaca
     9721 agctattcag gaacaaacac ctgtttcttc aactaagccg acagaagttc aagtagttga
     9781 aaaacctttc tctactgaat taatcaatcc aagaaaagaa gagaaacaat cttcagattc
     9841 tcaagaacaa ttagccgaac ataagaatct agaaacgaag aaagaggaga agatttctcc
     9901 aaaagaaaag actggggtaa atacattaaa tccacaggat gaagttttat caggtcaatt
     9961 gaacaaacct gaactcttat atcgtgagga aactatagag acaaaaatag attttcaaga
    10021 agaaattcaa gaaaatcctg atttagctga aggaactgta agagtaaaac aagaaggtaa
    10081 attaggtaag aaagttgaaa tcgtcagaat attctctgta aacaaggaag aagtttcgcg
    10141 agaaattgtt tcaacttcaa cgactgcgcc tagtccaaga atagtcgaaa aaggtactaa
    10201 aaaaactcaa gttataaagg aacaacctga gactggtgta gaacataagg acgtacagtc
    10261 tggagctatt gttgaacccg caattcagcc tgagttgccc gaagctgtag taagtgataa
    10321 aggcgaacca gcagtccaac cagagctacc ggaagcggtt gtaactgaca aaggtgagac
    10381 tgaggttcaa ccagagtcgc cagatactgt ggtaagtgat aaaggtgaac cagagcaggt
    10441 agccccattg ccagaatata caagaccaca agcaggtgca gtagttgaac ctgcaatcca
    10501 accagagtta ccagaagctg ttgtaactga caaaggagaa ccagcagtcc aaccagagct
    10561 accggaagcg gttgtaactg acaaaggtga gactgaggtt caaccagagt cgccagatac
    10621 tgtggtaagt gataaaggtg aacctaaaca ggtagcaccg cttccagaat atacaggacc
    10681 acaagccagc gctattgttg aaccagagca agtagcacca ctaccagaat acacaggggt
    10741 acaagccgga tcgatagtcg agccagagaa agtagaagca ccgaaagaat atactggtaa
    10801 aatcgaacaa cctagtgcag aagatactaa acctgaaaat gaggcaagct ctacaaatgg
    10861 ggaatcggaa cgtcctaaag ataaaattaa agaagaaaaa caagtcgaca agaaactaga
    10921 acttagaaat gtttcaaacg tggaattata tacggtagaa aataataaat atcgacatat
    10981 tacggctgta gatggtgctt tagatagttc attgaagtat ttcatgaagg taaaatcaga
    11041 aaattttaaa gatataatgt tgcctgttac taaaattgaa agtacaacaa aaaacaataa
    11101 agaagtatac aaaattgtgg ctcatgcaga aaatctaatt caacacgaaa acaatgttat
    11161 ttcgaatgac tatacatatt atttaccaaa aactcagcaa agtgaaactg gcgtctatac
    11221 atcatttaaa aatttagttg atgcaatgaa tagtgaccct aatggaacat tccatttagg
    11281 tgcaactatg gatgctcgtg aagttgaact tccggatgat caagaaagtt atgtaaaaaa
    11341 tgaattttac ggaaaattaa taggtgaaaa taatggtaag tattatgcta tttataactt
    11401 gaaaaaacct ttatttaaaa ctctaaacac cgctactatt cagaatcttt caataaaaga
    11461 agcgaatgtt tcttctaaag aagatgctgc tacaatatcg aaagaagcaa aatacaatac
    11521 tcttatagat aatgttcatt ctgatggtat tatagctggt gaacgtggaa ttggtggatt
    11581 ggtttcaaaa gtagataact cgagaatttc taatagtagt tttacaggca gaataactaa
    11641 cacatatgat acaactgtag ggtatgaaat tggtggttta gtaggtaaac tttctggttc
    11701 gcttgcttct atagagaaat caatagcatc gattgacata gcctctaatg caaaatcagg
    11761 agatcaaatt gttggtggta tagccggagt tgttgagaaa agtgcgacaa ttaagtatag
    11821 ctatgttgaa ggaaatgtta acaatgtgcg acactttggt aaagttgggg gagttgcagg
    11881 taatctttgg gatagagatt cacaagatgt aagtaaatca ggtaaactat catatgtttt
    11941 aagtgatgtt aatgtaacaa atggtaatgc tatatcgggt gataattttg ataatatgaa
    12001 agaagatcat gcttatagta gtaaaggcaa taaagtagta aatgtagtcc aagtagatga
    12061 tgaacttgtg actaaagatt cagatgtaca aagaggtacg gtattagatg ctgataaagt
    12121 aaaagagaaa aaggcagaat tggtttccaa acacagcact aaagtagaag attttgattt
    12181 tacttcaaga tacactacta tttacaatga agtaacaggt tatcaaaagt cgagagaaca
    12241 agtatataaa aatattgaaa aactattacc gttctataat cgagagacaa ttgttaaata
    12301 tggtaattta gtagatgaaa gcagcgagct atttactaaa gaacttctat cagttgttcc
    12361 tatgaaga
//
LOCUS       DAVLIK010000052        11982 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLIK010000052 DAVLIK010000000
VERSION     DAVLIK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11982
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.052"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(54..1103)
                     /locus_tag="VXE87_001732"
     CDS             complement(54..1103)
                     /locus_tag="VXE87_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0843237.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKIGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1223..3031)
                     /gene="glmS"
                     /locus_tag="VXE87_001733"
     CDS             complement(1223..3031)
                     /gene="glmS"
                     /locus_tag="VXE87_001733"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0843238.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(3223..4602)
                     /gene="bglA"
                     /locus_tag="VXE87_001734"
     CDS             complement(3223..4602)
                     /gene="bglA"
                     /locus_tag="VXE87_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0843239.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYDNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(4701..6554)
                     /locus_tag="VXE87_001735"
     CDS             complement(4701..6554)
                     /locus_tag="VXE87_001735"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0843240.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     SDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(6567..7826)
                     /gene="rseP"
                     /locus_tag="VXE87_001736"
     CDS             complement(6567..7826)
                     /gene="rseP"
                     /locus_tag="VXE87_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0843241.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(7848..8651)
                     /locus_tag="VXE87_001737"
     CDS             complement(7848..8651)
                     /locus_tag="VXE87_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0843242.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(8660..9418)
                     /locus_tag="VXE87_001738"
     CDS             complement(8660..9418)
                     /locus_tag="VXE87_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0843243.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(9649..10113)
                     /locus_tag="VXE87_001739"
     CDS             complement(9649..10113)
                     /locus_tag="VXE87_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0843244.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTAFYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(10202..11173)
                     /gene="ruvB"
                     /locus_tag="VXE87_001740"
     CDS             complement(10202..11173)
                     /gene="ruvB"
                     /locus_tag="VXE87_001740"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0843245.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            11334..11426
                     /locus_tag="VXE87_001741"
     CDS             11334..11426
                     /locus_tag="VXE87_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0843246.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
BASE COUNT         3515 a         2818 c         2253 g         3396 t
ORIGIN      
        1 attaattttc gtacaatatt tgttgtccta ataaacttga ttaggatttt ttattaagcc
       61 tctttcatag caaaataagc tcgtactttg ggtgcaactt gtgttccgaa gagttcaata
      121 gctctcagaa cctggtcatg aggcatagaa ccaagcggta gatgaagcat gaagcggtcc
      181 aatcctaaat cctctatcat gcgaatcaat ttttcggcca cctgatctgg attgccaaca
      241 aacatggcgc catttggccc tacctgctcc aaatattgct cataacgcaa ttcctgccag
      301 tgcggacggt ctttggaaat agcatccact acttgcttag tcggatggaa ataatctttc
      361 accgcctgct caccatcttc cgcaatccac ccccaagaat gggctcccac tttcaagtct
      421 ttgtcagcat ggcccgcttc gcttccaatc tcacgataag cctgaatcaa ctttttaaaa
      481 taacgtggat taccaccaat aatagcatat acaatcggta gaccagcctg agcaatcttc
      541 actgttgatt cgacatgacc acctgtagct atccacaagg gcaatttgtc ctgaactgga
      601 cgaggataaa cttctttacc agcaatcgtt tgagtcaatc gaccttgcca gtctaacttg
      661 gtcttttcat tgactaactg aagcaagtct aatttctcat caaaaagaga gtcgtagtct
      721 ttcaagtcat aaccaaacag agggaaagat tccgtgaaag agccccttcc agccataatc
      781 tccgatcgtc catttgacaa agcatcgata gtggcatact gttggaacaa acgaatcgga
      841 tccatgcttg acagaatgct gactgcactg gtcaaacgga ttttcttggt attgactgcc
      901 ccagcggcca ggacaatctc tggggctgat actgcaaaat ccgcccgatg gtgctcgcca
      961 atcccatata cgtccaaacc aatcttgtca gccagctcaa tctctgccac caactggcga
     1021 atgcgttcag catgactgta agtttgtcca gtcccttcaa gctccgttat ttccccaaat
     1081 gttgaaattc ccaattctac cattgtgatt ctccttgtct atctctgtcc ttcaatttga
     1141 aaaattattc taacacgaat cttaagtaca agcaaccaat ttgctcacaa gaaaaaggcc
     1201 tagataacta gactttttta gcttattcta ccgttactga cttggcaagg ttacgtggtt
     1261 tgtccacatc gaggccacgg tggagggttg caaagtaagc gactaattgc gttggtacga
     1321 ccattgaaat tggtgagagg tatggatgta cggtcgtaag gacgatatcg tcggtatctt
     1381 tggctacatt ctcttctgcg atagtgagga ctttggcacc acgggctgcg acctcttgga
     1441 tatttccacg agtatggttg gcaagaactg gatctgacaa gagagacaag acaggcgttc
     1501 cttcttcaat caaggcaatg gttccgtgct tgagttctcc tgccgcaaaa ccttcacact
     1561 ggatataaga aatctctttg agtttgagac ttgcttccat ggctacgtag taatcttgac
     1621 cacgtccgat gtaaaaggcg ttacgagttg tttcaagaag ttcacgaacc ttggcttcaa
     1681 tggtttcttt ctctgaaaga gttgattcga tagactgagc tacgattgac aattcatgaa
     1741 ccaggtcaaa ggcttgcgct ttagcattac catttgcttc tccgactgct tttgcaagga
     1801 aggcaagggc tgcgatttgc gctgtatagg ctttagttga tgccacggca atttcaggac
     1861 ctgcgtgaag gagcatggta tagttggctt cacgtgagag ggttgaacct ggaacgtttg
     1921 tcactgttaa gcttggaatt cccatttcat tagccttgac caaaacttga cgactatccg
     1981 ctgtttcacc agattggctg ataaagatga agagtggttt cttgctgaga agtggcatac
     2041 cgtagcccca ctcagatgag attccaagtt caactggtgt atctgtcaat tcttccaaca
     2101 ttttcttaga agcaaatcct gcatggtaag atgttccagc tgcaaggatg tagatgcggt
     2161 ctgcgtcttg aacagcctta atgatagcag gatcaatcac tacttgacca gcatcatccg
     2221 tgtaggcttg aatgagttta cgcataacag ttggttgctc atcaatttcc ttaagcatgt
     2281 agtaaggata agttccctta ccgatatctg acaagtcaag ttccgcagta tagctagcac
     2341 gttcacgact gttaccatca tagtcttgaa cttccacgct atcagccttg acgattacca
     2401 actcttggtc atgaatttcc atgtattggt tggtttcacg aatcatagcc atagcatctg
     2461 agcagaccat attgtagcct tccccaagac caatcaaaag tggagatttg tttttcgcta
     2521 catagatgac atctggattt tcagagtcaa tcaaggcaaa ggcatatgaa ccacggataa
     2581 tatgaagagc ttttttaaag gcttcaagaa ctgagagacc gtcttcttcc gcaaattttc
     2641 caatcaaatg tacggcgatt tccgtatctg tttgcccttt gaagtggtgc ccagcaaggt
     2701 attcttcttt aatttcaagg tagttttcaa tcaccccatt gtgaaccaag acaaaacgtt
     2761 ctgtctcaga gcggtgtggg tgagcattgt cttccgttgg tttcccatga gttgcccaac
     2821 gagtatgtcc gataccagtt gttccctcaa caccagctgt cttggcagac aattctgcga
     2881 tacgaccaac agccttcacc aaatggttat cagcaccatc taggacaaaa attcccgcag
     2941 aatcatagcc acggtattca agcttttcaa gcccttgaat caaaatatca gttgcatttg
     3001 tgtttccaac aacaccaaca attccacaca tagtatatac gacacaggca agctgtgctt
     3061 tctccttaaa attggtatag tctaattcat cttttataga atcagcaaaa acagtatata
     3121 cttgtttctt tcacttgtca agagtaaaaa ttggtatagt tcaaattaag ctcctgtaag
     3181 caaaaaactc tgaccgattg ggataatcag tcagagtcct ttttaaaatc cattattatc
     3241 gcttaattct ttgaaccagt ggcctgattt cttcagacga cgttcttgcg tttccaagtc
     3301 taattcgacc aaaccatagc gatttttata gctgttgagc catgaccagc agtcaataaa
     3361 ggtccaaatc aagtagccct tacagttggc accatcttca atggcacggt gaagttcacg
     3421 aagatgacct tttacaaagt caatacggta atcatcttga atcattccat cttgacggaa
     3481 tttttcttcc ccttcaacac ccataccatt ctcagtcaac atccattcaa tattgtcata
     3541 attttccttg atattttggg cgatgtcata aatcccttgc tcataaatct cccaaccacg
     3601 gtgagaattg attttacgtc caggcatcac ataaggctcg taaaaatgtt ctggtaagag
     3661 tggactatct ggatgcttag caaatcgagg agccataaca cgcaaaggtt gatagtagtt
     3721 cacaccaagg aagtccaccg tattatcacg aatgagttcc aactcttcct ctgtagcatc
     3781 aggtaaaaga ccgtgttcat gcaagatttc taccaactcc tgtggataag tccccaagac
     3841 agatggatct aagaaagatt gggcctgaaa aagggccgca atacgagctg ccttgacatc
     3901 agcaggatgc tggctacgtg gataagccgg tgtcaagttg aggacaatcc caatcttgga
     3961 atcaggcaaa agttcatggc aagccttaac agcccggctg ctggccaatt gtgtatgata
     4021 ggctacctta acagctgcct ctgcatccac cttatgtgga taatgggcat cataaaaata
     4081 accaaattct acaggaacga tgggctcgtt aaaggtaatc cattgatcca ctaaatctcc
     4141 ataagtctca aaacaaaaac gagcatagtc ttcataggct gagactgtcg ccttattttc
     4201 ccaaccatca ccatcctctt gaagggcaaa aggtaaatca aaatgataga gattgactaa
     4261 cagacgaatt cctttagcct taatagcctc aaagacctta cgataaaaat ccacaccttg
     4321 agggttgact tttccacagc cttgtggaaa aatccgtgac cactgaatag aagtccgaaa
     4381 ggctgtgtga ccagtctcta acaaaagctc aatatcccgc tcccaatttt cataaaaagt
     4441 cgatgtctta tctgaaccaa tcccattata gtaacgattt ggctccactt ggaaccagta
     4501 atcccagaga ttgtctccct taccgtcacc agctacacgt ccttctgtct gcggtccaga
     4561 agtagaggat ccccagacaa aatcctttgg aaatcttagc atacatttac ctctttatct
     4621 actcatttct cccattatac agaaaaaaca aggtaaaaac tagttacatt ttttccttgt
     4681 ttttcttctg attatagttt ttatttcttg cttaggattt caagcgtttc aagcacgtta
     4741 tctgcatgaa cctcaatggt gtcaccagtt gccttgatct taacttctac aatgccatcg
     4801 gccgcttttt taccaacagt gatacggatt ggaagaccaa tcaagtcact atcgctaaat
     4861 ttaacaccga cacgttcgtt acggtcatct gtcaagactt cataaccagc tcccatcaag
     4921 cttgcttcaa gtttttctgt caaggcttgc gcttcttcat ccttgacatt aacagtaatc
     4981 aaatgcacat caaacggtgc caattcttta gggaaattga ttccccaagc gtaacggtat
     5041 tcaccttttg gcgttttgtt aacaaagagg cgagcgtgtt gctccatcac tgctgaaaga
     5101 agacggctga caccgatacc gtaacatccc atgatgattg gcacagcacg accattttca
     5161 tccaagacat ctgctcccat gcttgctgaa tagcgagttc cgagtttgaa aatatgaccg
     5221 atctcaatac cacgcgcaaa gttaaggaca ccttgtccat ctggggaaat ttcaccctca
     5281 cgaacttcac ggatatccac atattctgca gtaaaatcac ggcctgggtt cacaccagtc
     5341 aagtggtagc catcttcgtt agcaccgaca actgcattgc gaacatcttg caccttacga
     5401 tctgcaataa ttttaatatt ctctggcaaa ccaactggtc caagtgaacc aaatcctgct
     5461 tgaacaacat tcgccacttc ttcttcgcta gcaacgtcaa agaaatctgc tcccaagtga
     5521 tttttcaact tgacttcgtt gagttggtca cttccaacta gaagggctgc aacaagctcg
     5581 ccatctgcaa tgtagaagag ggttttaatc gtttgttctt ctggaacatt gaggaaggct
     5641 gcaacttcat caattgattt aacatctggc gttgcaacac gagtaacttc ttcttcagcg
     5701 acaacacggt tgcttggttt gtactcgttt gttgccattt ctaagttagc tgcatagcta
     5761 gactcacttg agtaagcaat ggtatcttca ccagagacta tccatttgag caattctgcc
     5821 ttgatttctt cttgcacttc tgcaggaatt tcgtcaaatg aggcaactga cttgtccaag
     5881 acaacccagc ggtcaaggtc tgtacgagca gatgtaatgg ccataaattc ttggctatcc
     5941 ttaccaccca tggctccacc gtcaccaata atagccttga agtctaaacc actacgagtg
     6001 aaaatacgct cataggctgc tttgtactca tcataaacac tatccaaact atcatagtta
     6061 gcgtggaaac tataagcatc cttcatgata aactcacgtg tacgaagaag tccattacgc
     6121 gggcgttttt catcacgata cttgggctga atttgataaa ggttgagtgg caattgcttg
     6181 taagatttaa cagaatcacg gacaatagct gtaaaggttt cttcgtgagt tggacctaag
     6241 ataaagtctg atttttcacg gttttttagt ttgtaaaggt cttcaccata ggtttcgtaa
     6301 cgacctgatt cacgccacaa ttctgcacta agaagggcag gagccaacat ctcaacagca
     6361 ccaatctttt cgaattcttg gcgcatgatg tttttagctt tttcaatcac acggttggca
     6421 agtggtagat aagaataaac acctgctgaa acttggcgaa cataaccagc acgcaacata
     6481 agagcatggc tgataacttg agcatcgctt ggcatttcgc gaagcgttgg gataggcatt
     6541 ttactttgtt tcataatatt cctcgattat ctaaaaaaga gtcgcataat gtcattccaa
     6601 gtcacagcaa tcatcaagac aaccatgatg accactccgg ccaaggtgac ataggtttca
     6661 atttcttgtt tcaatggttt gcggcggatg gcttctagga tattgagcac aatcttacca
     6721 ccatccaagg ctggaatcgg aataagatta aaaatcccaa tattgatgga aatcattgcc
     6781 aagaagtaca agatattttc aattccattt ttagcagcat cactacttgc cttaaagata
     6841 gcaacaggtc cacccaactt gttcaaatcc ggttggaaaa tcagattttt cagagctgag
     6901 agaattcgga gagctgagtc agcagcagtt gtaaaaccac ctacaaacat ggatagaaaa
     6961 tctgacttaa cccccggttg aacacctaga aggtaacgac cttgactatc ttcgggtgta
     7021 acagtgactt gtttgtcact ccccttttca gaaatagtca catccaaagt cggtgccgtc
     7081 ttatctttgg tttctgtttc cacagcttgg atcaagcttt cccagttgct aacctcatgt
     7141 gagccaatct tggtaatttg tgccgtttct ggtactccta ccttggccaa ggcaccttgg
     7201 ggcatgatat ggaactgatt ggtatcaaca tctctgacac caccctgcat aaagattaaa
     7261 acccaaaaaa caacgacacc taagataaaa ttgttcatag gacctgcaaa attggtaatc
     7321 agtttgcccc agatagtcgc attttgatat tgaacatcta aaggtgcaat ccgaacctca
     7381 gtaccatctg cttccacaac cgttgcatcg tgatccactg caaatgtttt ttcttcttcc
     7441 agaaccaatc ctttgataaa gagcttgtct tcaaaatcaa actgggtcac ctgcataggg
     7501 agggctgttt gatccaattt tttacctgag agattgatgc gtttaacctt accatcatca
     7561 gcaagtgtca aactaacagg cgttcctgtc ttgatttcag ttgtatcatc accccaaccg
     7621 gccatgcgga catagccacc cagaggcaag attcgaatgg tataggccgt tccatccttg
     7681 ccaatgtgag caaaaatttt aggtcccata ccgatggcaa attcacgtac taaaatccct
     7741 gatttcttgg caaagtagaa gtgcccgaac tcgtgcacca ctacaataat cccgaaaacc
     7801 agaataaagg ttaaaattcc gagcatagcg tttcctccgt cttttgatta aaagagtcca
     7861 aataagtgca tgattggaaa tacaagcaac atactatcga aacgatccaa aacaccacca
     7921 tgtccaggga taaatttccc agaatcctta acaccaaaat gacgtttgat cgaactttct
     7981 agtaaatcac caaattgtcc agcaatgcta aagaaaatag caaagactga catcttgtaa
     8041 attccatatg gaagagcaac tgtactgtca actatcataa agataatggt tactaaaatt
     8101 gctcctaaaa taccacccaa ggcaccctca agggttttat taggcgatac ccttggtgct
     8161 aactttcgtt tcccatagtt catcccaaca agataggcac cactgtctgt cgcccagacg
     8221 atacacaagg ctaagagagc cttgtccaaa cctgcaacac gagcatctag taaagcatta
     8281 aatccaaagc ccacgtagaa gctcatagca agagggaaaa ccgcatcctc aatcgtataa
     8341 gacttgctaa aaacggtcgt tcctaacatg attgaaatca aaacactata ggcaaccaca
     8401 ttcccatcaa ctggcaaaaa agtcaggtaa ttctccaagg gaatggtcaa tgcaaaggtt
     8461 gcaaagaggg tcaagaggcc ctccatcgtc atggtctcta gacctctcat cttcaaaagt
     8521 tcatgcatgg ctagcatggc tatgattccg attgctatct gaagcaagag gcccccaatc
     8581 attaaaattg gtaggaaaat agccagggca atccctgcaa acaaggttct tttctgtaaa
     8641 tcctgggtca tatttcctcc taaactcctc caaatcggcg atgacgacga ttataggcaa
     8701 gaatagcttc ctgcaaggcc gcttcgtcaa aatcaggcca taaggtgtcc gtaaaataaa
     8761 gctcactata ggctccctgc catggaagga aattgctcaa acgtaattct ccactagtac
     8821 ggataatcaa gtctgggtct cgtaagtcct taggcaaatg ctgggtaaag agatagttac
     8881 caatcaattc ctctgtgatg tcacctggat tgattttggc atctaaaaca tcctgggaaa
     8941 tcaacttaag cgcctgtgta atctcagcac gtccaccata gttaagagca aaattaagaa
     9001 tcaatcctgt gttgttctta gtcaattcct cagccttggt taaagcttca aaggtttgct
     9061 taggcaggcg gtctgtctcc ccaatcattt gaatcttaac attattcgca tgtagttccg
     9121 ggacataatt atcataaaac tctactggca agttcatgat aaacttgact tcctgatctg
     9181 gacgggtcca gttttccgta gaaaaagcat agaccgtaat aaccttgacg cccagtttgt
     9241 tggctgcctt ggtcacggtt tgcaatgctt ccatgcccgc cttatgtcca aaaactcgcg
     9301 gttgcatacg ttttttagcc caacggccat tgccatccat gatgatgccg atatgagcag
     9361 gaacctgtgt cggaacctct acttccacag ccttatcttt cttaaaaaat ccaaacatga
     9421 tcttattcct attcaaaaat ctatcgtttc attataccat atttccccat tttcttctat
     9481 cactaagcta tttattctca ggcaccatgc ccatttttca aaaaaataag ccgcctgatt
     9541 gggcgacttt atttttatag ggagattatt atgaaaaagt tttaggagtt taagttaagg
     9601 tcttcttaac ttatgaactt agtgtacact ccctagctta aagtttcctt aagtattttt
     9661 aaaaatcaaa tttttccatt tctcctgcca atttttcttg gataaacgtg tttgatagag
     9721 ttccattcgg tcttcatttt ctaagaaatg aggagttgga cgaacttgaa aattcaaaat
     9781 atcctccaaa ccataaggtg cataaagttc aaaatctgat tcttcattca agcgcagtcc
     9841 aactgccgta caccgttctg gatacttact catagcatca cgagaactgg tatagaaagc
     9901 agtgtgagga ctgtgctggt gcatatagac ctgatttttc aattcccact ggtactgagg
     9961 aaaatcctct ctcagctttt tctccagtaa taaggtttcc tcataagaaa aatctggatc
    10021 aaagaaaatc acatctatat ctgtttcatg atcaaaaggg gatttgtctg acaaaagatt
    10081 ccagatgaaa tttctgacag aacctgctgc caactacgag tctttcaaac caaggtctcg
    10141 gatgatcgtc agaatggcca tcatatctgg attttctcta aaagcctcta agatttcttg
    10201 cttatttttc actgtattca taacctaagt gctcatatgc cttagcagtc gccacccgtc
    10261 cagaccgtgt ccgcatgata aaaccttttt gaatcaagta aggctcatac atgtcttcaa
    10321 ctgtctcacg ctcttcggcg atattgacag aaagagttcc tagaccaaca ggtcctccac
    10381 tgtacatctc aatcatggta cgaaggattt tttgatccac atagtccaaa ccttcatggt
    10441 caacatccag catagtcaaa gccttatcgg taataatatc atcgattacc ccattcccca
    10501 ttatctgggc aaaatcgcgc acgcgcttga ggagacgatt ggcaatacga ggggttccac
    10561 gactacgtag ggccaactca gatgctgcct catgagtgat ttccatctca aaaatatctg
    10621 ccgtccgctc gacaatttct gtcaagtcag catgggcata atactccata tgacctgtaa
    10681 tcccaaaacg tgcccgtagt ggatttgaga gcataccagc ccgagtcgtc gcaccaatca
    10741 aggtaaaagg aggcaactcc aaatgaacac tgcgactgcc ttcaccagcc ccaatcataa
    10801 tatctatgta gaagtcctcc atagcactat aaagcacctc ttccactgac attggcaaac
    10861 gatggatctc atcaataaaa aggacatccc caggctctaa ctcattcaaa atagctacca
    10921 gatctccggc tttttcaatg actggacccg acgtctgctt aagattgact cccagttcgt
    10981 tggcaataac aaaggccatg gtcgttttcc cgagacctgg aggcccaaat aagagcacat
    11041 gatccagcgc ttcatcccgc atttttgcag cttcaataaa gatttgtagc tggtccttga
    11101 ccttatcctg tccgatatat tcacgtaaat actgaggacg gagcgtgcgt tctactaact
    11161 cctcatcccc cattatctca ttatctaaaa ttctacccat ggctctatta tatcaaaaaa
    11221 ccaagccaca aacaaaaaag ccacctgatt gggtgactcc taagtttagc acttatgtgg
    11281 tataatatta tacggcactt ctacaccgcc tacgaaagga ggtgagatag cccatgatgg
    11341 aattagtact caaaactatc atcggaccaa ttgtggtcgg tgtcgttctt cgtatagtcg
    11401 ataaatggct aaacaaggac aaatagtgtc aaaaaagacc tcaagcttat ttggtcgtga
    11461 gcttggggtc ttttctagcc tatgatatag aactagtact caattccttt ttattatccc
    11521 atagttcacg aattttgtca aaggtttaca ttttcttcaa ccgctgtacg acaagacggt
    11581 taaaattaag agaacgttag ggattctatc aatttcatag aaattttgat ttcgtaaacg
    11641 aagagacaat cttacatgtc acttttcatt taatacgcca ctactagaca agcaaaatca
    11701 ttattacagt agttccagtc cttcaattaa cagtcactta caatcaaatt gagtttgaac
    11761 tagctgaagc gaccacagac ctatttctta gtcatattcg ctaaaaaaat cccctccaaa
    11821 atctcaaaaa gtccccgcca attccccgac caaaatccga aaaataccga aaaatatcga
    11881 aaaattattt ttagaatagt cccaaaaatc ctgaaataga gctaaaaaac tccacctgat
    11941 tgggtggagt taagggagat tattatgaaa aagaaaagtt ta
//
LOCUS       DAVLIK010000053        11607 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLIK010000053 DAVLIK010000000
VERSION     DAVLIK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.053"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            8..1648
                     /locus_tag="VXE87_001742"
     CDS             8..1648
                     /locus_tag="VXE87_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0843247.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWN
                     GGFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQN
                     GKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAIVSDEVWQAAQVKL
                     KSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDGTKYKDFYYYGCK
                     HRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTSEIEKE
                     IDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKIDELESSLI
                     DAKAKKQTIEAEKLTGDNIYKILIYFDKLYKVMNDVERRQLISALISEIQVYEEKQSN
                     GQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            1916..2482
                     /locus_tag="VXE87_001743"
     CDS             1916..2482
                     /locus_tag="VXE87_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843248.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            2804..2992
                     /locus_tag="VXE87_001744"
     CDS             2804..2992
                     /locus_tag="VXE87_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0843249.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3054..3812
                     /locus_tag="VXE87_001745"
     CDS             3054..3812
                     /locus_tag="VXE87_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0843250.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNETHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            3870..4724
                     /locus_tag="VXE87_001746"
     CDS             3870..4724
                     /locus_tag="VXE87_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0843251.1"
                     /translation="MLGVIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVT
                     EAIMNGGQKDDFIDAMKKYGSMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            4836..5720
                     /locus_tag="VXE87_001747"
     CDS             4836..5720
                     /locus_tag="VXE87_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0843252.1"
                     /translation="MKKVMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            5883..5960
                     /locus_tag="VXE87_001748"
     CDS             5883..5960
                     /locus_tag="VXE87_001748"
                     /inference="COORDINATES: protein motif:HMM:NF014902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV0843253.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHI"
     gene            6024..7622
                     /locus_tag="VXE87_001749"
                     /pseudo
     CDS             6024..7622
                     /locus_tag="VXE87_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390924.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            7897..8352
                     /locus_tag="VXE87_001750"
     CDS             7897..8352
                     /locus_tag="VXE87_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843254.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            8797..9273
                     /locus_tag="VXE87_001751"
     CDS             8797..9273
                     /locus_tag="VXE87_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0843255.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            9273..10031
                     /locus_tag="VXE87_001752"
     CDS             9273..10031
                     /locus_tag="VXE87_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV0843256.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTT
                     SAATVLHDLLFGELNQVEKEMLKSGEERLKDLTN"
     gene            complement(10429..11325)
                     /locus_tag="VXE87_001753"
     CDS             complement(10429..11325)
                     /locus_tag="VXE87_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0843257.1"
                     /translation="MDYKLISTYLDYCKTHKRLSSHTIRAYKNDLMQFYNSDYDHVES
                     YIEHLTQSNIKTNTLRRKIACMKVFYNYLKYQNIIEENPFNQLRFQFRTEKILPKTIP
                     YDILKNIFIYLEQKVVISKTDYQKQKAERNLLIISLLLSTGIRISELCHIHLKDINLS
                     NKTLHIIGKGKKERILFLGDQTTFNILETYINKTGKESNDFLFPGKHLPKPLSEQSVR
                     LILKRIVEQNSLSKTITPHMFRHSFATMLLDNDVDIRYIQQILGHSSISVTQIYTHVS
                     HSKQKEILSSFNPMSVIHSEIE"
BASE COUNT         4039 a         1589 c         2361 g         3618 t
ORIGIN      
        1 taatactatg tcaaaagaaa aaataaaagt atacctctat acacgagtat ctacgtcaat
       61 acagatagag gggtattcgt tagaggcaca aaaatcacga atgaaagctt ttgctattta
      121 caacgattat gaaattgttg gagagtatga agatgccggg aagtctggca agtctattga
      181 aggtagaata cagttcaatc gaatgatgga agatataaaa tctggaaaag atggagtatc
      241 ttttgttctt gtgtttaagt tatcaagatt tgcaagaaat gccgctgatg ttctttctac
      301 acttcagata atgcaggatt atggagttaa tcttatctgc gttgaagatg atggcattga
      361 ttcatctaaa gatgctggga aactaatgat ttctgtttta tcagctgtgg ctgaaataga
      421 aagagaaaac atccgtattc aaacaatgga aggtcgcatt caaaaagcaa gggaaggaaa
      481 atggaatggt ggctttgctc cgtatggata taaacttgaa gacggcaagc tgtttataaa
      541 tgaggaagag gcagttgcaa taagaacgat tttcgaccag tatgtaaata ctacgatagg
      601 agccaatggg atatctaaat acttagagaa tcatggaatt agaaaaatcc caagacagaa
      661 tggtaagaat cctgtatata atgggaaaat agcatttgga agaagaactt tagaaaaagt
      721 tcatggtaca agaaatgaat ataagcaggt tgaacaagat gaatatctaa tatctgaagg
      781 gatacatgaa gctatagttt ccgatgaagt ttggcaagct gctcaggtta agctaaaatc
      841 tcaagcaaag aaatatgagc atgtgaataa aggaaaagat acacgcacac acttgctttc
      901 tggaattgta aaatgcccga tatgtggagt gggaatgttt gggaacaagt gtatcaagaa
      961 aaagaaagat ggcacaaagt ataaagattt ttattactat ggttgtaaac ataggcagat
     1021 gataagaggt cataagtgta cattcagtaa gcaaattaga gaagaattgt tagatgatgc
     1081 tgttgcagag gtgattgtca agatagtaag taatccgaaa tttgcttcta tgatgcaaga
     1141 aaaaatcaac atgaaggtgg atacctctga aatagaaaaa gaaatagata attaccaaaa
     1201 ggaattgaga aagagtcatt ctacaaagtt taagctaatt gaggaaatag ataatttaga
     1261 tgttgaagat aagcattata agagaaggaa acaggattta gatgatagac tatatcgtat
     1321 gtatgacaaa atagatgaat tagaatcatc actaattgat gcgaaagcaa agaaacagac
     1381 tattgaagct gaaaagctta caggagataa catatataag attctgatct attttgataa
     1441 gctctataaa gtcatgaatg atgtagagcg taggcagtta atttcagctt tgatttctga
     1501 aattcaagtt tatgaagaaa aacaatctaa cggacaatgg ctaaaatcca ttacttttaa
     1561 gctaccaatt atagaagaaa atctcaacat aggtttggac aatgatgaac aagttgaatg
     1621 tgtaagttta ttagagaaac gtagttaatc ctcaaaaggt tccccaaacc ttttgagtcc
     1681 cactgacgca tcacgctgag gcggtatcac tgcttgtacg agttgaagca tcagcgaagt
     1741 aaaagtagat gttcagccaa tgcgacgagg tgagaccgaa ggtcgataag gtgtgttctg
     1801 ggtataggac tcgtaaagta agtaggaaat atgatgagat gatacagaga gcctgaattg
     1861 gtcaggtgac gtgcttattt acattagcct gataatgaaa atggagagat tatcgatggt
     1921 tatattggaa ttgtaccaaa atgattattc taaagattta gtagcatttg attccataga
     1981 agatgggaaa gcctttgtag ctcaaatccc gggatacact ctggaaacag aagatggttt
     2041 tgaagtggag tattttaatc ctaaaaacat accggattat atggaaatta tttttaacgg
     2101 aaatattgtt cctttatcta aatttatgtt cgatcctgag gaaaatgtaa acattatttg
     2161 gaaagagatt tcaaatttat ccctcaaaaa tgatagagtg atcgaaggat attcaaaaat
     2221 tgatgcatat gtcgttaaca accatgaagt taaagcctat gtcgaaacaa gagaaacgaa
     2281 ctatcgtaaa gcaaaagact tcttagaaag ccgcggatat gaaatcgaca gaagcttttt
     2341 cggaagtgaa gacggtgaag cgattcttta cagaaaaaaa gggatcgaag tttggcattt
     2401 cttgtgtcac ttagacccaa tgtttgtaga gattgaagat gtagaaggat atgttaaaga
     2461 agaagttgga gagattcaat agtcaaccaa agttccttgt gagtatatac ctttgctagt
     2521 aaaagagtca aaacgttata acgaaggggg ggaagaaaac ccttgagtgt aagtcttttt
     2581 cttgtttaga gggaaagtat tagagtagcc gctcataatt tatactagat ttgataactg
     2641 atttgagaca gattttattt ctataaatat tgtgaaaatt ttttaatacc aaagatttaa
     2701 agttactgtg ttaaaaatcc tctccacttt taaactaatg tattataaaa gccagttgac
     2761 acaagtgtga cacttgtgat agaattaact tgaggtgatg aaaatggcaa ccgataaaaa
     2821 tagaataatg attagcttgg atgataaaaa tctagagaaa cttgaaaatt tagtagaaga
     2881 tgctagagat agaaggggaa tgcgactaac aaagtcccag gttattgaat tactcctaaa
     2941 taccgttgat tatttcgatg atattatggg ggctatttac tcaaaaaaat aagagcaaaa
     3001 ttgctattat tttttacaaa ttggtgtaac actagtgata taggagtgat gaaatggttg
     3061 tttatattag acaaagtaaa ttaccaagtg aggtttcaat taataaatac aatgctcaag
     3121 taggtgccta cttacaagga gaagaagtta ttttatatca atctttttct gaaataaaag
     3181 agttaacaag tgaagatata gttgtagatt atataatgga gactagagca ttactaaaaa
     3241 tgatgggctt aaacgttccg gtttatgact atcctattga gcttaaagag ttttatggtc
     3301 gaaagattta tgctggtatt ttaggagaga ttgtgaatat acctgataat tggggaaaat
     3361 ttattaagcc taaagctggt tcaaaagtct ttactggaag agttgttaat gaaacccatg
     3421 atttaatagg tattggtcta cctttcgact atcctatatg gattagtgag gttgtagaat
     3481 tcatagctga atggcgttgt tttgtgttag atggtcgcgt attagatgtt cgaccctata
     3541 caggtgatta tcatgcacaa tttgatgcaa gtgtaattga tgaagcgata tcatgttgga
     3601 aagatgcgcc aatagcttat ggactagata tcggtgttac tcgcgatggc agaacacttg
     3661 ttgttgaagt aaatgatggt tatgcattgg gaaattatgg cctatctcct ttaaaatcaa
     3721 tcaattttca tagagctagg tggaaagaaa tggtaaaacc ctattttgaa aaaaatgaaa
     3781 tttttaaaat ccaacaggat gttattttct aaaataaata tggtagataa ccaatataaa
     3841 aagcatcaaa atgaacaagg aggaatctga tgcttggagt aattattgga gatattgtcg
     3901 gttctgttta cgaatggaac aatatcaaaa caaaggactt tcctttattt cggaaggact
     3961 gcttttttac agatgacacg gttatgacct gtgctgttac agaagcaatt atgaatggtg
     4021 gacaaaaaga cgatttcatt gacgcgatga agaaatatgg cagcatgtat ccgaatgctg
     4081 attacggtgc tcggtttaat gcatggctaa acagcgataa tcgtgagcct tataatagct
     4141 ttgggaatgg atcagctatg cgtatttctc catgtgcttg gatcatggac tgtggttttt
     4201 atgcgaaaac tggtatgtgg ccatcatcta gaggacttac gagtctttct gcagaggtaa
     4261 ctcataatca tccagaaggt gtcaaaggcg ctatggctac agctgatgct atctttctat
     4321 gtcgttttta ctttggtggt tattgtagag agtacgagca atcaattaac gacaatccta
     4381 cagagtgtaa aagacgaatt aaggattata tagaaaaaga atacgattac aatctatctc
     4441 aaactttaga tgaaatccgt cctaactatc gttttaacga aacatgtcag gaaactgtcc
     4501 ctcaagccat tatcgccttt cttgaaagta gagacttcga agatgcgata agaaatgcca
     4561 tctcacttgg tggcgacagt gatactctcg cagcaatcac ttgtaacata gcagaggcag
     4621 cttacggtat tcctgattgg atcaaggata aggcctattc ttacttggat gaacccttaa
     4681 aggatgtagt taggcgatgg gaaaatagaa taaaagcgta ttaatctcca gtacgtcaga
     4741 tttctctttt ctgtattttc attgtataat aggattacat ttacttgcat acgacgaaat
     4801 gtaaacattt ctgtttaaaa ttaaggataa aatcaatgaa aaaagtaatg gtaattatca
     4861 accctacttc tggtggcgag aaggctttgg attacaaaga aaagctggag aataaagcaa
     4921 aagaatactt tgaatatgtt gaaaccaaaa ttaccgaaaa agcgctggat gcaacacatt
     4981 ttgctgaaga agcttctcgt gagcagtatg atgcagtggt tgtgtttggt ggagatggaa
     5041 ctgtcaatga agtcatttca ggtattgatg agagagacta cattcctaag ttagggatta
     5101 tcccaggcgg tacgggtaac ctcattacaa aacttttgga aatcaatcaa gacatcgatg
     5161 gcgcaattga cgaactggat tttgatttaa ccaataagat tgatatcggt aaagcaaatg
     5221 acaactattt tggttatatc tttagtatcg gttctctgcc tgaggcgatt cacaatgttg
     5281 aaatagagga caaaacaaaa ttcggtattt taacctatgc tgtaaatacc atgaagtctg
     5341 tcatgacaga tcaggtcttt aacattaagg ttgagacaga aaatggaaat tatgttggtg
     5401 aagctagcca tgttttggtc cttttgacaa attacttcgc tgataagaaa atctttgaag
     5461 aaaacaagga cggctatgcc aacattttga ttctgaaaga tgcctctata ttctccaaat
     5521 tatccgtcat tcctgattta ttaaaagggg atgttgtcgc aaatgataat atcgagtata
     5581 tcaaagcgcg taatattaaa atctcttcag atagtgaatt ggagtcagat gttgacggag
     5641 ataaatcaga taacctacct gtagaaatca aagtcctagc tcagcgagta gaagtatttt
     5701 caaaaccgaa agaggattag tatatagaga aagccttttt taaggctttt tgtatacttt
     5761 aaaagatagt tcctttaaca acggacattc cttgcaaata gtttacaaaa atagtatact
     5821 ggatttattg agtttgaaaa cgtttgcgta aaatttgaat aaatacttta ggagacaaat
     5881 tgatggaatt gagtgctatt taccataggc ctgagtcgga gtatgcctat ctttataagg
     5941 ataagaaact ccatatttga attcgaacta agaaagggga cattgaaagc atcaacttgc
     6001 actatgggga cccttttatc tttatggagg agttttatca ggatacaaaa gaaatggtca
     6061 agataacttc tggtacctta tttgaccatt ggcaggttga agtgtcagtt gactttgcac
     6121 gtatccagta tctctttgag ctcagagata cagaaggtca aaatattttg tatggcgata
     6181 aagggtgtgt ggaaaattct ctagaaaatc ttcatgcaat tgggaatgga tttaagttgc
     6241 cttatcttca tgagattgat gcctgcaagg ttcctgactg ggtttcaaat acggtatggt
     6301 atcagatatt tcctgaaaga tttgccaatg gcaatgctct attaaaccca gaagggactt
     6361 tagactggga ttcatctgtc acacctaaga gcgatgattt ctttggtggt gatttacagg
     6421 ggattattga tcgtatggat tacttgcaag acttgggtat tactggacta tatctttgtc
     6481 ccatctttga atctacaagc aatcacaagt acaatacgac agattacttt gaaattgacc
     6541 gttattttgg agacaaggag acctttcggg aactggtgga tcaagcgcat catcgtggca
     6601 tgaaagtcat gatggatgcg gtatttaatc atattggttc gcaatctctt caatggaaaa
     6661 atgtcgtcaa aaatggcgaa cagtctgctt ataaggattg gttccatatt caacaattcc
     6721 cagtgacaac tgaaaagcta gttaataaga gagacttacc ctatcatgtt tttggtttcg
     6781 aggactatat gcctaagcta aatacagcca atccagaggt caagaattat cttttaaagg
     6841 ttgcgactta ttggattgaa gagtttaata tcgatgcttg gcgtttggat gtggctaatg
     6901 agattgacca tcagttctgg aaggattttc gtaaggcagt tttagctaaa aatcctgatc
     6961 tttatatcct aggagaagtc tggcatacat ctcagccttg gctaaatgga gatgagttcc
     7021 atgccgtcat gaattatcct ttatctgata gtatcaagga ctatttctta cgaggaatta
     7081 agaagacaga ccagttcatc gatgaaatca attgagagtc tatgtattac aagcagcaga
     7141 tttcagaggt catgtttaat ctcttggatt cacatgatac agagcgaatc ctgtggacgg
     7201 ccaatgaaga tgttcaactg gttaaatcag ccttagcctt tctcttttaa caaaaaggaa
     7261 caccgtgcat ttattacgga accgagctag ccttgactgg aggaccagat ccagattgtc
     7321 gtcgttgtat gccttgggaa cgtgtatcaa gtgacaatga tatgctgaac tttatgaaga
     7381 ggctgattaa gattcggaaa tacgcgtcag taatcatttc gcatggcaag tatagccttc
     7441 aagaaatcaa atctgatcta gtagctctgg aatggaaata cgaaggacgg atcctcaaag
     7501 caatattcaa ccaatcaaca gaagattatc ttttagagaa agaagcagta gcactagcaa
     7561 gcaattgcca agaattggag aatcagcttg tcatctctcc agatggattt gtgattttct
     7621 aaaaactagt tgatgaagat tatggtacat ttcatatctt atatagtata ataaggatag
     7681 ttactaaact tgtaaaggag aacttaaatg aattgtagag gacatgaaac aagacaaaga
     7741 attgttagag attttgaagt ttagcctaaa gcacatatta agctgttagc aaatcaacaa
     7801 aaacatagtg atgcaggagc aactattgaa gatgaatatt atgtatttat cgctgagagt
     7861 aaaattgatg gcaagaagga agttattcag tgttgcatgg gtgcggcaag ggatttttta
     7921 gaactaatta atcacaaagg gctacctctt tttaatccgc ttgtaggtga ttctcatgta
     7981 aataatagac aagaatatga caatacaggg agtggaaatt tacaacctga aaagtggaat
     8041 gaaactgcaa agcagcttta taatgttata atgtggttga ttattttatg gaatgctaag
     8101 ccggatacac ctttatttaa ttttaaagac gaagtaatta agtataaaac atatgagcct
     8161 tttgaaagca gtataaaaag agtaaatact actataaaga atggtagtaa agggaaaact
     8221 ctgactgaga tgattaatgg ctacagagcg gataacgata ttagagatga aatttgtaac
     8281 tttaatattc tgaaaaataa aattcgtgat atgaaagacc aacaaggaaa tacaatggaa
     8341 tcttactttt agttattgtt gaattttggg tattctataa aatatcctaa ttgagattta
     8401 aatagtagac tatacaatat agttaaaata tcagtaaaaa caacacttta ttgaggtatt
     8461 ggatacgctt tgctaatagc ctaataatca catgtggagt gttgctacaa cgaaaaaggt
     8521 gataatcctt gatttcaagc tattttataa gcattttgtc tttgtagata aaggcaattt
     8581 tgacaataaa aatcctaaaa ggtgaatcgt tatagatgta tttgtagata tcgtttgcgc
     8641 atcgaaaaaa ttaatacaag aataaatatt tatagctctt taggtgactt ttatagaagt
     8701 aaagtttagg atagaaaaac aagaaataac gcaccatttt tggtgcgtta tgctttttta
     8761 tgctataatg gatttataaa aataaaggag tttgctatga ttggaaagaa cataaaatcc
     8821 ttacgtaaaa cacatgactt aacacaaccc gaatttgcaa ggattgtagg tatttcacga
     8881 aatagtctga gtcgttatga aaatggaacg agttcagtct ctaccgaatt aatagacatc
     8941 atttgtcaga agtttaatgt atcttatgtc gatatcgtag gagaagataa aatgctcaat
     9001 cctgttgaag attatgaatt gactttgaaa attgaaattg tgaaagaaag aggtgctaat
     9061 ctattatctc gactctatcg ttatcaagat agtcagggaa ttagtattga tgatgaatct
     9121 aatccttgga ttttaatgag tgatgatcta tctgacttga ttcagacaaa tatctattta
     9181 gtagaaaatt ttgatgaaat agagagatat agcggctatt tggatggaat tgaacgtatg
     9241 ttagagatat ctgaaaagcg gatggtagct taatggaaat ccaagattat actgatagtg
     9301 aattcaaaca tgctttagca aggaatcttc gttcactgac aagaggaaaa aagtccagta
     9361 aacaacctat agcgattttg cttggaggtc aaagtggtgc cggtaagact acaattcatc
     9421 gtattaaaca gaaagaattt caaggaaata ttgttatcat agatggtgat agttttcgtt
     9481 ctcagcatcc acactattta gaactgcagc aagaatatgg caaagacagt gtagaataca
     9541 ccaaagattt tgcagggaaa atggtagagt ctttagtaac cgaattgagt catttgggat
     9601 acaatctttt gatagaggga actttacgaa ctattgatgt tccaaagaaa acagcacaac
     9661 tattaaaaaa taaggggtat gaggtacaat tagccttaat tgcaaccaag cccgaattgt
     9721 cctatctgag cacccttatc cgatacgaag aactgtatgc tatcaatcca aatcaagcac
     9781 gcgcaactcc aaaagaacat catgatttca ttgtaaatca tctagttgat aatacacgac
     9841 aattggaaga actggctatc tttgaaagca ttcaaattta ccaacgagat agaagttgtg
     9901 tatatgattc aaaagaaaat acaacttcag cagcaaccgt tcttcatgat ttactatttg
     9961 gagaattgaa tcaagtggag aaagagatgc ttaaatcagg agaagaaaga ttgaaagatt
    10021 taactaattg aaatggttgt tagaacacaa attttagaat atagtctact tataactttt
    10081 gttagttgtt tgaggtgggc aaaaagtttt taaaatcaaa aaaaacgcat agtatcaggt
    10141 gttgaaaaaa cttgatatta tgcgttttct tgttggaaga tttactccat tttcttcagg
    10201 aattgagatt ttgcccatct ctttttatta tatttaagga tatttgaaag ctgtatttta
    10261 gaaaaacaaa tatggagttt ttaatacgga cgtaatatag tataaatgct gattcaaagt
    10321 gaagttttat atgttttttg cttttgttga gtataaaatc tattaactaa agtcgaacta
    10381 caaacattga tttaagataa agtaaactgt aaccttcaga aatgtctctt actcgatttc
    10441 agaatgaatc actgacatag gattaaaaga actaagtatt tctttttgtt ttgaatgaga
    10501 tacgtgagta tagatttgtg tgactgatat agaactgtgt ccaagaattt gttgaatgta
    10561 tcgaatatct acatcattat ctagaagcat tgttgcaaag ctatgtctaa acatatgtgg
    10621 tgtaatagtt ttagataagc tattttgttc aacgattctc tttaaaatta aacgtacact
    10681 ttgctctgac aatggtttag gcaaatgttt ccctgggaat aggaaatcat tagattcctt
    10741 tccggtttta tttatatatg tttctaatat attgaaggtc gtttgatctc ctaaaaatag
    10801 gatacgctct ttcttcccct ttcctataat atgtagtgtc ttattggaaa gattaatatc
    10861 tttgagatga atatgacaaa gttcagaaat tctgataccc gttgaaagta aaagggaaat
    10921 aataagtaga tttctttcag ctttttgttt ttgatagtca gttttagata taactacttt
    10981 ctgttctaaa tatataaaaa tgtttttcag aatgtcatac ggaatcgttt taggcaatat
    11041 tttttcagtt ctaaattgaa aacgcaattg attgaagggg ttctcttcaa ttatgttctg
    11101 gtattttaga tagttataaa acaccttcat acaagcaatt tttcttctta atgtattcgt
    11161 ttttatgtta gattgtgtca aatgttctat ataggattcg acatgatcat agtctgagtt
    11221 ataaaattgc ataagatcat tcttataagc gcgaatcgtg tgtgaactca aacgcttatg
    11281 agttttgcaa taatctaagt aagtagaaat aagtttataa tccataaaaa tctcctttat
    11341 caataatcat gctattataa acctatttgg gtgctttgta tagtgataat aaattgttat
    11401 cactagtata ccataaattc atttttagta gtttgatttg tataatgatt ttttagtctt
    11461 gaattgtcac attaagtgca cattttctct tgtgaattta gataaggata tttaatttat
    11521 aaaaggaaat tttatagtat agttgtgatt tttatatttt cagtttaagc aaaatagtgg
    11581 tggtatgcta tatgtttttc tttgtta
//
LOCUS       DAVLIK010000054        11310 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLIK010000054 DAVLIK010000000
VERSION     DAVLIK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.054"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..422
                     /locus_tag="VXE87_001754"
                     /pseudo
     CDS             1..422
                     /locus_tag="VXE87_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            460..762
                     /locus_tag="VXE87_001755"
     CDS             460..762
                     /locus_tag="VXE87_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0843258.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            770..1572
                     /locus_tag="VXE87_001756"
                     /pseudo
     CDS             770..1572
                     /locus_tag="VXE87_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1621..2085
                     /locus_tag="VXE87_001757"
     CDS             1621..2085
                     /locus_tag="VXE87_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0843259.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2242..2667
                     /gene="lacA"
                     /locus_tag="VXE87_001758"
     CDS             2242..2667
                     /gene="lacA"
                     /locus_tag="VXE87_001758"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0843260.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2698..3213
                     /gene="lacB"
                     /locus_tag="VXE87_001759"
     CDS             2698..3213
                     /gene="lacB"
                     /locus_tag="VXE87_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0843261.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3224..4153
                     /locus_tag="VXE87_001760"
     CDS             3224..4153
                     /locus_tag="VXE87_001760"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0843262.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            4155..5135
                     /gene="lacD"
                     /locus_tag="VXE87_001761"
     CDS             4155..5135
                     /gene="lacD"
                     /locus_tag="VXE87_001761"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0843263.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5369..6121
                     /locus_tag="VXE87_001762"
     CDS             5369..6121
                     /locus_tag="VXE87_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0843264.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLITENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIINAEGENEVELVESIDKRKEILRNVEEV
                     LTDYAIQRTKKNNHFYDRFMIHLNYFLDYLDRSRDDNQSLLDMEDHIKQSYPKAFEIG
                     SKIYDVITQHTGLDLYKSERVYLVLHIQRLLS"
     gene            6157..6474
                     /locus_tag="VXE87_001763"
     CDS             6157..6474
                     /locus_tag="VXE87_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0843265.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6476..8170
                     /locus_tag="VXE87_001764"
     CDS             6476..8170
                     /locus_tag="VXE87_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0843266.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8385..9791
                     /gene="lacG"
                     /locus_tag="VXE87_001765"
     CDS             8385..9791
                     /gene="lacG"
                     /locus_tag="VXE87_001765"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0843267.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILAANGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDVIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9834..10091
                     /locus_tag="VXE87_001766"
     CDS             9834..10091
                     /locus_tag="VXE87_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0843268.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(10369..11130)
                     /locus_tag="VXE87_001767"
     CDS             complement(10369..11130)
                     /locus_tag="VXE87_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0843269.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
BASE COUNT         3635 a         1940 c         2286 g         3449 t
ORIGIN      
        1 atcaagaata actctttgat caggtagcaa gcttgttgga ggaacgagaa attgtaactc
       61 caacttatcg tgaagccttg atcacgcgtg aaaagtcatt tccaactggt ttagatatgg
      121 aatttctagg aaaggacttg ccaaatgtag cgattcctca cacagatatt gttcataatt
      181 tggctgaaaa agttgtggtc gttcgattag agaaaccggt gactttccat aatatgattg
      241 cgccagataa ggaagtagaa gtatccttgc tcttctttat cattaataat tcaagttcaa
      301 gtcaaacgaa cattcttgct cagttaatgg acttcttcac aggaaatggt catcttgaag
      361 acctatcaaa aatttctgaa ccagaagccc tttatgctta cattgctgaa gcaaccgctt
      421 aatcttgtct attaaaaaat aaaatcggag gaaatccaaa tgattaaaat tcttgctgcc
      481 tgcggtgcag gtgttaactc aagtcaccaa attaaaagtg ctctagaaga agaactttca
      541 aaccgtggtt acgatgttca ctgtgatgca gttatggtga aagatgtaaa cgaagacctt
      601 atgaaaggtt acgatatctt tacaccaatc gctgcaacag accttggttt tgaaccaggt
      661 atcccagtta tcgaagctgg gccaatctta ttccgtatcc cagcaatgag cgttccagta
      721 tttgacaata ttagacttcc tgcgaaacaa aacatggtat agtagttcta tgaatgatga
      781 agcaagtaaa caactaactg atgcacgatt taagcgtctt gttggtgttc agcgcacgac
      841 ttttgaagag atgttagctg tattaaaaac agcttatcaa cttaaacacg caaaaggtgg
      901 acgaaaacct aaattaagcc tagaagacct tcttatggcc actcttcaat atgtgcgaga
      961 atatcgaact tatgaagaaa ttgcggctga ttttggtatc cacgaaagca acttactccg
     1021 tcggagctaa tgggttgaag taactcttgt tcaaagtggt tttacgattt caagaactcc
     1081 tctcagttct gaggacacgg taatgattga tgcgacggaa gtacaaatca atcgccctaa
     1141 aaaagaatta gcgaatgatt ctggtaaaaa gaaatgccac gctatgaagg ctcaagcgat
     1201 tgtcacaagt caagggagat tgtttctttg gatatcactg tgaactattg tcatgatatg
     1261 aagttgttca aaatgagtcg cagaaatatc ggacaagctg gtaaaatctt ggctgacagt
     1321 ggttatcaag ggctcatgaa gatatatcct caagtacaaa ctccacgtaa atccagcaaa
     1381 ctcaagccgc taacagttga agataaaacc tataaccatg cgctatctaa ggagagaagc
     1441 aaggttgaga acatctttgc caaagtaaaa acgtttaaaa tgatttcaac aacctatcga
     1501 aatcatcgta aacgcttcgg attacgaatg aatttgattg ctggcattat caatcatgaa
     1561 ctaggattct agttttgcag gaagtctaat aaagaaacta gcaaggtcag gccttacttt
     1621 attggtggac atccaggatt taattgtcct ctacttgatg atgaagtcta tgaagattat
     1681 tatctagagt ttgagaaaga agagacttgc tctgttccac gtcctttccc agaaacaggt
     1741 atgttggatt tccaagatag aagtccatgg ctagagggac aaaaagaaat agatcttagt
     1801 tatgatcttt tcagcaaaga tgcagtgact ttggatgaat tgcaatctcg aacaattgcc
     1861 cttcgttctc ttaaacatga taggggattg aaagtgcatt ttgcagaatt tccaaacctc
     1921 atcatctggt caactttgaa caagggacct ttcattacct ttgaaccatg gtctggcttg
     1981 tcaacattcc ttgaagaagg agatcattta gaagataaga agaatgtttg tctcttagaa
     2041 gccaatcagg ttgaagaatt agggtttgag atagaagttt tataaaaaag taaaaaataa
     2101 ataacaaaaa caaacacaaa ctgttgactt cttcaaacaa tagtagtata ttatgtttgt
     2161 gaggactaat tgactgtttt ttaaagacag ccaatacact gctggaatcc agcatagaaa
     2221 aaataaaaag gagtatacaa tatgtctatt gttatcggtg cagatgctgc aggtttgaga
     2281 ttgaaagaag ttgtgaaaga cttcttagaa aaagaaaact tccaccttgt ggatgttaca
     2341 gctgaaggtc aagactttgt tgatgtgact ctcgctgttg ctgcagaagt aaacaaagaa
     2401 gaacaaaacc ttggtatcgt gattgatgct tatggagctg gtccatttat ggttgcaact
     2461 aagatcaaag gaatggttgc tgcagaagtt tctgatgaac gttcagctta tatgactcgt
     2521 ggccacaaca actcacgtat gatcactatg ggtgcacaac ttgttggtga tgaattggct
     2581 aaaaacatcg ctaaaggatt tgttaatggt aaatacgacg gtggtcgtca ccaaatccgg
     2641 gttgacatgt tgaacaaaat gggctaatta gattatagta agaaaggtaa gttaaaaatg
     2701 agaattgcaa ttggatgtga ccacatcgta acagatgaaa aaatggcggt ttcagaattt
     2761 ttgaaatcaa aaggatatga agtcattgac tttggtacat atgaccatac acggactcac
     2821 tacccaatct ttggtaaaaa agtaggggaa gctgtaacta gcggtcaagc tgatcttgga
     2881 gtatgtatct gtggtactgg tgttggtatc aacaacgctg taaataaagt tccaggtgtt
     2941 cgttctgcct tggttcgtga tatgacaaca gccctttatg ctaaagaaca attgaacgct
     3001 aacgttattg gttttggtgg taaaattact ggtgaattgc ttatgtgtga tatcatcgaa
     3061 gctttcatcc atgctgaata caaaccaact gaagaaaaca aaaaattgat tgcgaaaatt
     3121 gaacatgttg aaagtcacaa tgctcaacaa acagacgcaa acttctttac agaattcctt
     3181 gagaaatggg atcgtggaga ataccacgac taagaggtga cctatgattt taacagtcac
     3241 aatgaaccca tccatcgata tttcctatcc cttggatgag ttgaagattg atactgtcaa
     3301 tcgtgtggtg gatgtaacca aaacggctgg tggtaaggga ctcaatgtta cccgagtact
     3361 ttcagaattt ggcgattctg ttcttgctac tggtttagtg ggtggcaaac ttggtgagtt
     3421 tttggttgaa catatcgata atcaagtaaa gaaagatttc ttctcaatta agggagaaac
     3481 tcgtaactgt atcgctattc tccacggaga caaccaaaca gaagttcttg aaaaaggtcc
     3541 tgaagtattg gaacaggaag gtcaagagtt tttggaacat ttcaaaaaac tcttggagtc
     3601 agttgaagta gtggccatct caggtagtct gccagctggc cttccagttg attactatgc
     3661 gagcttggta gaacttgcta atcaagctgg caagcctgta gtcttggact gctcaggtgc
     3721 agcacttcag gctgttcttg aatcacccca taaaccaaca gtcatcaaac caaataatga
     3781 agaattgtct cagcttcttg gaagagaagt ttctgaggat ttggatgaat taaaagaagt
     3841 acttcaagaa cctttgtttg cagggattga atggattatc gtttcacttg gtgccaacgg
     3901 tacttttgcc aaacatggtg acactttcta caaggtagat attcctagaa ttcaggtggt
     3961 aaatcctgtt ggatctggag actctactgt ggcaggaatt tcttcaggac ttcttcacaa
     4021 agaatcggat gcagaattac tcatcaaggc aaatgtcctt ggtatgctca atgctcaaga
     4081 aaaaatgact ggtcatgtca acatggccaa ctatcaagtt ctatatgatc aattaatagt
     4141 aaaagaggta taaaatggct ttaacagaac aaaaacgtgt acgcttagaa aaactttctg
     4201 atgaaaatgg tatcatctca gctcttgcat ttgaccaacg tggtgctttg aaacgcctca
     4261 tggctcaaca ccaaacagaa gaaccaactg tggcccaaat ggaagaactt aaagtcttgg
     4321 tagcagatga attgactaaa tacgcttcat ctatgcttct tgaccctgag tatggacttc
     4381 cagcaactaa agctcttgat gaaaaagctg gccttctcct tgcttatgaa aaaacaggtt
     4441 atgacacaac aagcacaaaa cgcttgccag actgcttgga tgtctggtct gcaaaacgta
     4501 ttaaagaaga aggtgcagat gcagttaaat tcttgcttta ctatgatgta gatagctcag
     4561 acgaactcaa tcaagaaaaa caagcctaca tcgaacgcat cggttctgag tgtgtggctg
     4621 aagatatccc attcttcctt gaaattcttg cttacgatga aaaaattgcg gatgcaggtt
     4681 ctgtagaata cgcgaaagta aaaccacaca aagttatcgg cgctatgaaa gtcttttcag
     4741 acccacgctt taacattgat gtcttgaaag ttgaagttcc tgttaacatt aaatatgttg
     4801 aaggcttcgc tgaaggtgaa gtagtttata cacgtgaaga agcagcagcc ttcttcaaag
     4861 cgcaagatga agcaacgaac ttgccataca tctacttgag tgctggtgta tcagctaaac
     4921 tcttccaaga tactcttgta tttgctcatg aatcaggtgc aaactttaac ggagttcttt
     4981 gtggccgtgc tacatgggca ggatcagttg aagcttacat caaagatggt gaagcagcag
     5041 ctcgcgaatg gcttcgcaca actggatttg aaaacattga tgagctcaat aaagttcttc
     5101 aaacaacagc gacttcatgg aaagaacgtg tgtaagaaag tcctcctagt ttaggaacat
     5161 gaatctaaaa aaatttaaaa aaagttgtat gtaaaggttt acaaaataac ttacttgtgc
     5221 tatacttaaa tcacaagtta atacaaggtg agtgttacta agtaatatta ggcatgatca
     5281 caggtgaatt agaaatcagc tgattttcta gttcatttgt ggtcattttt tgtactcata
     5341 tacctttaag atataaaagg aggttgacat gtatcgaatt ctaaatccaa tgaatcacaa
     5401 tgtctcgctt gtcagaaatg ataagggaga agaggtgatt gtaattggta aggggattgc
     5461 attcggaaag aagaaggggg atttgattac tgaaaatcag gttgagaaaa tctttcggat
     5521 gaagaccgaa gagtccagag aaaactttat ggctcttctc aaagatgttc cgcttgattt
     5581 tatcacagtg acctatgaaa tcattgataa gctatcaaag aaatatcatt atccgattca
     5641 agagtatctc tatgtaacct tgacagatca tatttactgt tcttatcaag ctctaactca
     5701 aggaaggtac aaggatagta atctgccaga tatttccgct aagtatcctg tcgcttttca
     5761 aatcattaat gctgaaggtg aaaatgaagt ggaacttgtg gagtcgattg ataagaggaa
     5821 agaaattctc aggaatgttg aagaagtttt aacggactat gcaattcaac gaactaaaaa
     5881 gaataaccat ttctatgatc gctttatgat ccatttgaat tatttcttgg attatttaga
     5941 cagatctaga gatgataacc aatcacttct ggatatggaa gatcatatta aacaatccta
     6001 tccaaaagcc ttcgagattg gttccaagat ctatgatgtg attacgcaac atacgggtct
     6061 tgatttgtat aaaagtgaac gagtttatct agttctacat atccaacgtt tattgtcata
     6121 aaaatttatt taaaactata taaggagaat tctatcatga atagagaaga agtaacattg
     6181 ttaggttttg aaatcgtagc ctatgctggc gatgctcgtt caaaactatt ggaagccttg
     6241 aaggctgctg aagctggtga ttttgaaaaa gcggacgctc tggtagagga agctggtagc
     6301 tgtattgcag aggctcacca cgcgcaaaca agtctattga ctaaggaagc ttctggtgag
     6361 gacttagcgt atagtgtgac catgatgcat ggtcaagatc acttgatgac aactatcttg
     6421 ttaaaagacc taatgcacca tttaattgaa ctttacaaga gaggagttaa ataaaatgga
     6481 taagttaata atttttattg agaaaggaaa gcctttcttt gaaaaattat cgagaaatat
     6541 atacttaaga gcgataaaag atggttttat ttccagtatg ccagcagtat tattctcaag
     6601 tatttttata ctaatagctg ctgtgcccaa tatttttggg tttaaatggt ctgatgaaca
     6661 gttagctttt attttgaaac cttacaacta ctcaatggga attttagctc tcttagtagc
     6721 tgggacaact gcaaaatcgt taacagattc agttaataca cgtagtatgg agaaaaccaa
     6781 ccaaatcaac tacatgtcaa cttttttagc agctgttgtt ggattgttaa tactggcagc
     6841 tgatccaatt gaaggtggat ttgctaatgg tcttttaggt actagaggat tacttactgc
     6901 atttttggca gcttttatta cagtaaatat ctataaagta tgtattaaaa ataatgtaac
     6961 cattagactt cctgaagagg ttccaccaaa tattgcacaa gtttttaaag atgttattcc
     7021 gtttgcctta tctgttcttt caatatatgg attggattta attgttagaa atatttttgg
     7081 tacaaatgta gcagaatctg ttggtaaaat attagcccct ctattttcag ctactgatgg
     7141 ttatatcggt ttagctattg tatttggtgc ttatgctttc ttttggtttg ttggaattca
     7201 tgggccatct gttgtagaac ctttaattgt agctatcagt tatgcaaata tagaagctaa
     7261 tgttcagctt gtgcaagctg gtatgcacgc agataaaatt ttaaatccag ttactcaaac
     7321 ttttgttgta acaatgggtg gtactggtgc aacactagta gttccattta tgtttatgtg
     7381 gttatgtaaa tcaaaaagaa atagaattgt cggacgtgcg tctgtagttc ctactttctt
     7441 tggcgtaaat gaaccaatcc tatttggtgc tccaattgtt ttaaatccta tcttctttat
     7501 tccgtttgtt actgctccta ttatcaatgt ttggattatg aaattttttg tagatgttct
     7561 acaaatgaat agtttcagta ttattttacc ttggacaaca cctgctccaa ttggtattgt
     7621 tatgggaacg gcgctggctc cattgtcatt cgtcttggct ataactttaa tcattatcga
     7681 cactttaatc tattatccat ttgttaaagt ttatgaccat caaattttag aagaagaacg
     7741 gaaaggaaac tcttcatctg aattgaaaga aaaagttgct gcaaacttca acactgcaaa
     7801 agcggatgct attcttgaaa aagcgggtgt cgatgcagca caaaatacca tcactgaaga
     7861 aacaaatgtc ctcgttctct gtgctggtgg aggtacaagt ggactccttg caaatgcttt
     7921 gaataaggca gcagcagaat acaatgtccc tgtgaaagca gcagcaggcg gctatggtgc
     7981 tcaccgtgaa atgttaccag agtttaatct agttatcctt gcccctcaag ttgcttcaaa
     8041 ctttgaagat atgaaggcag aaacagataa gctcggtatt aaacttgcta agacagaagg
     8101 cgctcaatac atcaaattaa ctcgtgatgg aaaaggtgcc ctagcattcg tacaagagca
     8161 attcgattaa ggctaggaac tgtgaaacag tctcccatcg ttacggaaat cgctatggcg
     8221 aatttcctaa tcgccttatt aattcgtcgg taaaaagata tcgtttttac ctcctcatgt
     8281 cacaattcag tgacttggta caagaagtga gatggagaag catggctcac tgactcctct
     8341 cctctcactt ttactttatt taaatcaaga aataggtgaa aaaaatgaca aaaacacttc
     8401 caaaagactt tattttcggt ggcgcaacag ctgcttatca agcagaaggt gctacacata
     8461 ctgatggaaa aggaccagtt gcttgggata aatatcttga ggataactac tggtacactg
     8521 ccgaaccagc tagtgatttt tacaatcgat atccagttga cctcaagcta gcagaagagt
     8581 atggtgtcaa tggtattcga atttctattg cttggtcacg tattttcccg actggttacg
     8641 gccaagtaaa tgctaaaggt gttgagtttt atcataattt atttgcagag tgtcacaaac
     8701 gtcatgttga gccttttgta actcttcatc actttgacac gccagaagct ctccactcaa
     8761 atggagactt cttaaaccgt gaaaatatcg aacattttgt agactacgct gctttctgtt
     8821 ttgaagaatt tccagaagta aactattgga caacctttaa tgaaattgga ccaatcggtg
     8881 atggtcaata tttggttggg aaattccctc caggtatcca gtacgacctt gccaaagtct
     8941 ttcaatcaca ccacaatatg atggtgtctc atgcacgcgc ggtaaaattg tacaaagaga
     9001 aaggctataa aggggaaatt ggtgttgttc acgccctgcc tactaaatat cctctagatc
     9061 atgaaaatcc agcagatgtt cgtgcagctg agttggaaga tattattcac aacaaattta
     9121 ttttggatgc aacctatctg ggtcactact ctgaaaagac tctggcaggg gtagaggcta
     9181 tcttggctgc caatggtggt agcttggatc ttcgtgaaga agattttaca gcattagaag
     9241 ctgcaaaaga cttgaatgat ttcctaggaa tcaactacta tatgagtgac tggatggaag
     9301 cctttgatgg agaaactgaa attatccata atggtaaagg tgaaaaagga agctctaagt
     9361 atcaaatcaa aggtgttggt cgtcgtgtag ctcctgacta tgtaccacgc acggattggg
     9421 attggattat ctaccctcaa ggtttgtatg accaaatcat gcgcgtgaag aaagattatc
     9481 ctaactacaa gaagatttac atcactgaaa atggtctcgg ctataaagat gagttcgttg
     9541 ataacactgt ttacgatgat ggtcgtattg attacgtgaa acaacacttg gagatcttgt
     9601 ctgatgtgat tgcagatgga gctaatgtaa aaggttactt catttggtca ttaatggatg
     9661 tcttctcatg gtcaaacggt tatgagaaac gttatggtct cttctacgta gattttgaaa
     9721 ctcaagaacg ttatcctaag aaatcagctc actggtacaa gaaagtagcg gaaactcaga
     9781 ttatagacta gtagaattag tcattagata tagaatttta gtgagtcaaa aagatgttca
     9841 aagattttat ccaatctatt tatgaaaaag tttatattat aaatttcgaa aaatgctctc
     9901 aaataccgtg tttgacgagt gaagaattga aaagtcttgg aaaatggtat gtctcgactg
     9961 gtaaagaatg gatttgtcat tcagatgatg agctggaaga atttaaaaat ctatttttaa
    10021 attttatcaa tcctgaagaa tgggatacta tctcctttga ttcagatttt atgccgtttc
    10081 aacaatcgta accaatttct caaaaaagtt aaatcttata tttagtactc tgtaaaactc
    10141 ttatctaatc acgttgctta tactcaatga aaatcaaaga gcaactttaa actaggaagc
    10201 gagtcgcaga tttctcaatg catagctttg aggaattggg caaaaagtct ttgatataga
    10261 aaaacgcata gtatcaggtg tttcaacacc tgatactatg cgttttattg tgggaagatt
    10321 tacttttttc ttctgaaatt gagttgttac ccaggctctt tcagtttatt aaggcttgat
    10381 gactttaatg tgtttagata gcttaaaaag gattgaatca cttagtttag aatctgaaac
    10441 aatagtatca agatttgata cattataaaa agtataaaaa tcaaacttat tgaacttgct
    10501 atgatctgcg agtaaatatt ttttattaga attatttaaa gcgatgcgtt gagcctctcc
    10561 ctcttcctcg ctaaaagtag ctagagctcc gttttgaata ccattacagc taacgaaagc
    10621 tttagaaaat tggagattag agagattttg tagggtcaat gtaccaacaa aagcacctgt
    10681 aatatcgcga taatttccac ctattaaaat caaatctgtt aattttcgtt cgcttaaaat
    10741 cagaaaaaca ggtagactgt tggttacgac gcggatattg tcaataggca actcacgcgc
    10801 aaaaaactct aatgttgttc ctggtccaat gaaaatagtt tctctttctt ctactagact
    10861 gcctgcaaaa tgggctattt cttgtttttc tgccgtttgg agggcttgtt tttcaatatt
    10921 tgatcgctca ttagtcaaaa gggagttggt tcgaagtttt tcagctccac catgcacacg
    10981 aatcagcaaa tctttatcag ctaattcctg taaatagcgc cttgcagtca tatctgaaac
    11041 ggctatttcg tccataatct gtttaactgt tatggttcct ttactattta ctatctctaa
    11101 aattttggct aatttttctt gtttgagcat attatcacct cgtttcctac tactatctta
    11161 ccataaacaa actcatcatt caaatacaaa aacaacaaaa taaaacaaaa acaaaaatat
    11221 cgaggtttat tttcaaaact ttcgatattt ttattaagtt attattttgt tgtttctagt
    11281 ttactttttg atggttaaga gtggtggaga
//
LOCUS       DAVLIK010000055        10887 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLIK010000055 DAVLIK010000000
VERSION     DAVLIK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.055"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(212..1843)
                     /locus_tag="VXE87_001768"
     CDS             complement(212..1843)
                     /locus_tag="VXE87_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV0843270.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVDLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGDLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFETTL
                     NLAPEMTIAFAHGTFNITNTIIQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2136..7115
                     /locus_tag="VXE87_001769"
     CDS             2136..7115
                     /locus_tag="VXE87_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0843271.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAILFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTVQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTSDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFSDVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGKDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNTVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7205..8401
                     /locus_tag="VXE87_001770"
     CDS             7205..8401
                     /locus_tag="VXE87_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0843272.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINVLEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8537..9064
                     /locus_tag="VXE87_001771"
     CDS             8537..9064
                     /locus_tag="VXE87_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0843273.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9141..9497
                     /gene="glnR"
                     /locus_tag="VXE87_001772"
     CDS             9141..9497
                     /gene="glnR"
                     /locus_tag="VXE87_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0843274.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     FQQGRFASVQSPFGRG"
     gene            9534..10880
                     /gene="glnA"
                     /locus_tag="VXE87_001773"
     CDS             9534..10880
                     /gene="glnA"
                     /locus_tag="VXE87_001773"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0843275.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
BASE COUNT         3463 a         2011 c         2395 g         3018 t
ORIGIN      
        1 atttaattca ctatagtaaa atgaaataat aacaggacaa atcgatcagg acagtcaaat
       61 ctatttctaa caatgtttta gaaatagagg tgtcctattc tagtttcaat atactatata
      121 tctgcagaat actctttcag tttcattcag cctagtcttg cttaggaaaa agtaaaaagc
      181 catccaatta tgatggatag cttcttggtt cttagatttg ttctgcaaaa accttttcag
      241 caaggttcat agcgtggtct gatacacgag tgtagtgtga gatgatgtcg ataaagttga
      301 ccccagcttg tgttgaacat tcgcctttgt tgaggcgttt gatgtgggtt tttctgagaa
      361 cacgttctat cttattgatt gcttcatgac gttctacaag actgcgtgct ttttcaatat
      421 cattgttttc cacactatcc agagcatctt tgataaagtc actagtttgg cggtaaactt
      481 cctctaattc tttcaaggcg gcatcagaaa attcaacatt tttccgttga agatagtcag
      541 tcagattgag tagagcctct gtgtggtctc caatccgttc caaatcacgg gaggaatcaa
      601 ggatattggt aagcacttca ctttcttttt ggctgagagc ttcgcttgaa agggcaatga
      661 gataacgtgt taattgctca tcgatggtgt taattgcttc ttcggtttta tgcccttttt
      721 cagcaacttt ttcatccaag tcaatgatgt acttatagga aaggtcaaag gctttagcag
      781 cgtagtttcc taagtgcaag agctcttttt tagcatttcc tagagcgata gatggggctt
      841 gtttgatgaa atgttcatca agatataagg gttcgtattt gacaacctcg tcctctccag
      901 gaataatctt ggttacaaag taagccagag ctccgataaa tggaaattgg ataatggtgt
      961 tggtaatatt aaaggttccg tgagcaaagg cgatggtcat ttccggtgct agatttagcg
     1021 tagtttcaaa ccaatgaatc aggacagtaa aaggaactag aaaaataacg cagacgactg
     1081 ttccgataac gttgaaggca acatgagctc ctgctacccg tttagctgca atattagccc
     1141 ctaaagaggc aatgatggct gtaatggttg tcccgatatt gtcaccaaat agaactggca
     1201 aagctccctg taggtcaatt agatcgccgg cgtagaggtt ttgtaaaatc ccaatggtag
     1261 ccgaagaagc ttgaattagc aaggtcaagc cagtaccgac aaagacaccc aaaacaggat
     1321 tcttacttag ctcaatcata tagtccttaa agacctgtaa atccttgagt ggagccattg
     1381 cgccgctcat gagattgagg gcaaaaaaga taccaccgac accaaagagg atgcgtccga
     1441 tattattgac tgtccgattt ttcgtaaaaa agagacagac ggcaccgata aagagcatag
     1501 gtagggcata gttacctaat ttaaaaccga tgagaaagga tgtgacagtt gtcccaatat
     1561 tagcacccat gacaatcccg atagcctgac gtaaggttaa gagaccggca ctgaccaggt
     1621 cgactgtaat aactgttaca ccagaactag actgaattag agcagtcatc ccaataccaa
     1681 ccagaactcc aaagaaagga ttactagtat atttgtcaat gtaaaaacga aggcgatctc
     1741 cagcagcttg ttgcaaaccg tctcccatgg tcttgatgct atataagaat agccccagac
     1801 cacctaaaaa gtgaaataaa atttcctgcc aattaatgga catttctttt tcctccgaaa
     1861 aataatcgcg gaatatctcc tattctattt taaaggataa aagtaaatct aacaagtgtt
     1921 aatgtcaagt ttgtaaaaga aaattataat tgataagtgt attattttta agagttttta
     1981 accttatttt agatttgtgc aaacagttat tgttttttgt ctaaaaatgt tttaggataa
     2041 aaatgtgatt atcatggttc tagagtttga taaaaaacta cagaatataa agcgctttct
     2101 tgaaaacaac aaaatcaatc ttttaggagg agaaaatgaa gaatccattt tttgaaagac
     2161 gttgtcgtta cagtattcgt aagttatcag taggagcctg ctcgctgatg attggtgcta
     2221 ttttatttgc tggtccagcc ttggctgaag aaactgcagt tcctgaaaat agcggagcta
     2281 atacagagct tgtttcagga gagagtgagc attcgaccaa tgaagctgat aagcagaatg
     2341 aaggggaaca tgctagagaa aacaagctag aaaaggcaga aggagtagcg atagcatctg
     2401 aaactgcttc gccagcaagc aatgaagctg caactactga aactgcagaa gcagctagcg
     2461 cagctaaacc agaggaaaaa gcaagtgagg tggttgcaga aacaccatct gcagaagcaa
     2521 aacctaagtc tgacaaggaa acagaagcaa agcccgaagc aactaaccaa ggggatgagt
     2581 ctaaaccagc agcagaagct aataagactg aaaaagaagt ccagccagat gtccctaaaa
     2641 atacagaaaa aacattaaaa ccaaaggaaa tcaaatttaa ttcttgggaa gaattgttaa
     2701 aatgggaacc aggtgctcgt gaagatgatg ctattaaccg cggatctgtt gtcctcgctt
     2761 cacgtcggac aggtcattta gtcaatgaaa aagctagcaa ggaagcaaaa gttcaagcct
     2821 tatcaaacac caattctaaa gcaaaagacc atgcttctgt tggtggagaa gagttcaagg
     2881 cctatgcttt tgactattgg caatatctag attcaatggt cttctgggaa ggtctcgtac
     2941 caactcctga cgttattgat gcaggtcacc gtaacggggt tcctgtatac ggtacactct
     3001 tcttcaactg gtctaatagt attgcagatc aagaaagatt tgctgaagct ttgaagcaag
     3061 acgcagatgg tagcttccca attgcccgta aattggtaga catggccaag tattatggct
     3121 atgatggcta tttcatcaac caagaaacaa ctggagattt ggttaaacct cttggagaaa
     3181 agatgcgcca gtttatgctc tatagcaagg aatatgctgc taaggtaaac catccaatca
     3241 agtattcttg gtacgatgcc atgacctata actatggacg ttatcatcaa gatggtttgg
     3301 gagaatacaa ctaccaattc atgcaaccag aaggagataa ggttccggca gataacttct
     3361 ttgctaactt taactgggat aaggctaaaa atgattacac tattgcaact gccaactgga
     3421 ttggtcgtaa tccttatgat gtatttgcag gtttggaatt gcaacagggt ggttcctaca
     3481 agacaaaggt taagtggaat gacattttag acgaaaatgg gaaattgcgc ctttctcttg
     3541 gtttatttgc cccagatacc attacaagtt taggaaaaac tggtgaagat tatcataaaa
     3601 atgaagatat cttctttaca ggttatcaag gagaccctac tggccaaaaa ccaggtgaca
     3661 aagattggta tggtattgct aacctagttg cggaccgtac gccagcggta ggtaatactt
     3721 ttactacttc ttttaataca ggtcatggta aaaaatggtt cgtagatggt aaggtttcta
     3781 aggattctga gtggaattat cgttcagtat caggtgttct tccaacatgg cgctggtggc
     3841 agacttcaac aggggaaaaa cttcgtgcag aatatgattt tacagatgcc tataatggcg
     3901 gaaattccct taaattctct ggtgatgtag ccggtaagac agttcaggat gtgagacttt
     3961 attctactaa gttagaagta actgagaaga ccaaacttcg tgttgcccac aagggaggaa
     4021 aaggttctaa agtttatatg gcattctcta caacttcaga ctacaaattc gatgatgcag
     4081 atgcatggaa agagctaacc ctttctgaca actggacaaa tgaagaattt gatctcagct
     4141 cactagcagg taaaaccatc tatgcagtta aactattttt cgagcatgaa ggtgctgtaa
     4201 aagattatca gttcaacctc ggacaattaa ctatctcgga caatcaccaa gagccacaat
     4261 cgccgacaag cttttctgta gtgaaacaat ctcttaaaaa tgcccaagaa gcggaagcag
     4321 ttgtgcaatt taaaggcaac aaggatgcag atttctatga agtttatgaa aaagatggag
     4381 acagctggaa attactaact ggctcatctt ctacaactat ttatctacca aaagttagcc
     4441 gctcagcaag tgctcagggt acaactcaag aactgaaggt tgtagcagtc ggtaaaaatg
     4501 gagttcgttc agaagctgca accacaacct ttgattgggg tatgactgta aaagatacca
     4561 gcctaccaaa accactagct gaaaatatcg ttccaggtgc aacagttatt gatagtactt
     4621 tccctaagac tgaaggtgga gaaggtattg aaggtatgtt gaacggtacc attactagct
     4681 tgtcagataa atggtcttca gctcagttga gtggtagtgt ggatattcgt ttgaccaagc
     4741 cacgtaccgt tgttagatgg gtcatggatc atgcaggggc tggtggtgag tctgttaacg
     4801 atggcttgat gaacaccaaa gactttgacc tttattataa agatgcagat ggtgagtgga
     4861 agctagctaa ggaagtccgt ggcaacaaag cacacgtgac agatatcact cttgataaac
     4921 caatcactgc tcaagactgg cgcttgaatg ttgtcacttc tgacaatgga actccatgga
     4981 aggctattcg tatctataac tggaaaatgt atgaaaagct tgatactgag agtgtcaata
     5041 ttccgatggc caaggctgca gcccgttctc taggcaataa caaggtacaa gttggctttt
     5101 cagatgtacc ggctggagca actattactg tttatgataa tccaaattct caaactccgc
     5161 ttgcaacctt gaagagcgaa gttggaggag acctagcaag tgcaccattg gatttgacaa
     5221 atcaatctgg tcttctttat tatcgtaccc agttgccagg caaggaaatt agtaatgtcc
     5281 tagcagtttc cgttccaaaa gatgacagaa gaatcaagtc agtcagccta gaaacaggac
     5341 ctaagaaaac aagctacgcc gaaggggagg atttggacct tagaggtggt gttcttcgag
     5401 ttcagtatga aggaggaact gaggacgaac tcattcgcct aactcacgca ggtgtatcag
     5461 tatcaggttt tgatacgcat cataagggag aacagaatct tactctccaa tatttgggac
     5521 aaccggtaaa tgctaatttg tcagtgactg tcactggcaa agacgaagca agtccgaaaa
     5581 ctattttggg aattgaagta agtcaggaac cgaaaaaaga ttacctagtt ggtgatagct
     5641 tagacttgtc tgaaggacgc tttgcagtgg cttatagcaa tgacaccatg gaagaacatt
     5701 cctttactga tgagggagtt gaaatttctg gttacgatgc tcaaaagact ggtcgtcaaa
     5761 ccttgacgct tcattaccaa ggccatgaag ttagctttga tgttttggta tctccaaaag
     5821 cagcattgaa cgatgagtac ctcaaacaaa aattagcaga agttgaagct gctaagaaca
     5881 aggtggtcta taactttgct tcaccagaag taaaagaagc tttcttgaaa gcaattgaag
     5941 cggccgaaca agtgttgaaa gaccatgaaa ctagcaccca agatcaagtc aatgaccgac
     6001 ttaataaatt gacagaggct cataaagctc tgaatggtca agagaaattt aaggaagaaa
     6061 agacagaact tgatcgctta acaggtgagg ttcaagaact cttggctgcc aaaccaaacc
     6121 atccttcagg ttctgcccta gctccgcttc ttgagaaaaa caaggccttg gttgaaaaag
     6181 tagatttgag tccagaagag cttacaacag cgaaacagag tctaaaagat ctggttgctt
     6241 tattgaaaga agacaagcca gcagtctttt ctgatagtaa aacaggtgtt gaagtacact
     6301 tctcaaataa agagaagact gtcatcaagg gtttgaaagt agagcgtgtt caagcaagtg
     6361 ctgaagagaa gaaatacttt gctggagaag atgctcatgt ctttgaaata gaaggtttgg
     6421 atgaaaaagg tcaagatgtt gatctctctt acgcttctat tgtgaaaatc ccaattgaaa
     6481 aagataagaa agttaagaaa gtatttttct tacctgaagg caaagaggca gtagaattgg
     6541 cttttgaaca aacggatagt catgttatct ttacagcacc tcactttact cattatgcct
     6601 ttgtttatga atctgctgaa aaaccacaac ctgctaaacc agcaccacaa aacacagtcc
     6661 ttccaaaacc tacttatcaa ccggcttctg atcaacaaaa ggctcctaaa ttggaagttc
     6721 aagaggaaaa ggttgccttt catcgtcaag agcatgaaaa tgctgagatg ctagttgggg
     6781 aacaacgagt catcatacag ggacgagatg gactgttaag acatgtcttt gaagttgatg
     6841 aaaacggtca gcgtcgtctt cgttcaacag aagtcatcca agaagcgatt ccagaaattg
     6901 ttgaaattgg aacaaaagta aaaacagtac cagcagtagt agctacacag gaaaaaccag
     6961 ctcaaaatac agcagttaaa tcagaagaag caagcaaaca attgccaaat acaggaacag
     7021 ctgatgctaa tgaagcccta atagcaggct tagccagcct tggtcttgct agtttagcct
     7081 tgaccttgag acggaaaaga gaagataaag attaaatatc gaaaaatctt gtgaaatctt
     7141 tccttatatt tccaaagtgt gatataatag tttcgaataa aataaataaa ggagtttttg
     7201 taacatggca aaacttactg ttaaagacgt tgacttgaaa ggtaaaaaag tcctcgttcg
     7261 tgttgacttc aacgtaccat tgaaagatgg cgtaatcact aacgataacc gtatcacagc
     7321 agctcttcca actattaagt acatcatcga acaaggtgga cgtgcaattc ttttctctca
     7381 ccttggacgt gtgaaagaag aagctgataa agctggtaaa tcacttgctc ctgtagcagc
     7441 tgacttggca gcaaaacttg gtcaagatgt tgttttccca ggtgtcactc gtggtgctga
     7501 attggaagcg gcaatcaacg ttcttgaaga tggacaagtt ctcttggttg aaaacactcg
     7561 ttacgaagat gttgacggca agaaagaatc taaaaacgat cctgaacttg gtaaatactg
     7621 ggcatcactt ggagatggta tcttcgtaaa cgatgcattc ggtacagctc accgtgcaca
     7681 cgcatctaac gttggtatct cagcaaacgt tgaaaaagca gttgctggtt tccttcttga
     7741 aaacgaaatt gcctatatcc aagaagcagt tgaaactcca gaacgtccat tcgtggctat
     7801 ccttggtggt tcaaaagttt cagacaagat cggtgttatc gaaaacttgc ttgaaaaagc
     7861 tgataaagtc cttatcggtg gtgggatgac ttacacattc tacaaagcac aaggtatcga
     7921 aatcggtaac tcacttgtag aagaagacaa attggatgtt gcgaaagctc ttcttgaaaa
     7981 agcaaatggt aaattgatct tgccagttga ctcaaaagaa gctaacgcat ttgctggtta
     8041 cactgaagtg cgtgacactg aaggtgaagc agtttctgaa ggcttccttg gtcttgacat
     8101 cggtccaaaa tctatcgcca aatttgacga agctttgact ggtgccaaaa cagttgtatg
     8161 gaacggacct atgggtgtat ttgaaaaccc agatttccaa gctggtacaa tcggtgtgat
     8221 ggacgctatc gtgaaacaac caggagttaa atcaatcatc ggtggtggtg actcagctgc
     8281 cgcagcgatt aaccttggcc gtgcagacaa gttctcatgg attagtacgg gtggtggagc
     8341 atcaatggaa cttcttgaag gtaaggttct tccaggactt gcagccttga cagaaaaata
     8401 agattttata aacaaatcaa agaagagagg gatgaaagtt cctcttttct tttgcttaaa
     8461 ataaaaacgc ttcctctcaa ctattactca taaaaatcac cgatttatga taaaatggaa
     8521 atagaaagtt gagattatga gttattttaa aaaatataaa ttcgataaat cccagttcaa
     8581 acttggtatg cgaaccttta aaacaggtat tgctgttttt ctagttctct tgatttttgg
     8641 cttttttggc tggaaaggtc ttcaaattgg tgctttgaca gccgttttta gcctgaggga
     8701 gagttttgat gagagtgttc attttgggac ttcgcgtatt ctaggaaata gtatcggtgg
     8761 actctatgcc ttggtcttct tcttattaaa tacctttttc cacgaagcct tttgggtgac
     8821 cttggtagtt gttccaatct gcaccatgtt aaccattatg acaaatgtag ccatgaataa
     8881 caaagcaggg gttattggtg gtgtagcagc tatgttaatc attaccctat caattccaag
     8941 tggtgagaca attttgtacg tgtttgtgcg tgtattagaa acgtttatgg gagtttttgt
     9001 cgcaattatc gtaaattacg atattgatcg tattcgtctc tttttagaga aaaaagaaaa
     9061 ataatgttac attttataac attatcaatt gacgtttgtc tttttttaga ctataataga
     9121 cagaaagaag gaaattgtaa atgaaggaaa aagaatttcg ccgaaatatg gctgtttttc
     9181 ctatcggcag tgttatgaag ttgaccgatc tatcggcgcg tcagattcgt tattatgaag
     9241 atcaagagtt gatcaagccc gatcgaaacg aaggaaatcg tcgcatgtat tccttgaatg
     9301 acatggatcg tctgcttgaa atcaaagatt atatctctga aggttataat atcgctgcca
     9361 ttaagaaaaa atatgctgaa cgtgaagcga aatccaagaa agcggttagt cagactgaag
     9421 tacgtcgtgc acttcacaat gaactcttcc aacaggggcg ttttgcttca gtacagtcac
     9481 cttttggtcg cggttaggca accgcaagta gtcatagatt aaggagaaaa cttatgccaa
     9541 tcacagctgc agatattcgt cgtgaagtca aggaaaaaaa tgttaccttt attcgtctta
     9601 tgttctcaga tattttggga accatgaaaa acgtcgaaat tcctgctaca gatgaacagt
     9661 tagataaggt cttgtcgaac aaggttatgt ttgatggatc ttctattgaa ggttttgtac
     9721 gtatcaatga gtcggatatg tacttgtacc cggacttgga tacatggaca gtcttccctt
     9781 ggggagatga aaatggaagt gttgcaggtc tgatctgtga tgtttataca acagaaggtg
     9841 aaccatttgc gggtgaccct cgtggtaatt tgaaacgagc tcttcgtcac atggaagaag
     9901 ttggattcaa atccttcaac cttggtccag agccagaatt cttcctattt aagttggatg
     9961 aaaatgggga cccaacactt gaagtgaatg acaagggtgg ctactttgat ttggcaccta
    10021 ctgaccttgc ggacaacaca cgtcgtgaga ttgtgaatgt cttgaccaaa atgggatttg
    10081 aagtagaagc gagtcaccac gaggttgcgg ttggacagca tgagattgac tttaagtacg
    10141 atgaagttct ccgtgcttgt gataagattc aaatctttaa acttgttgtt aaaaccattg
    10201 ctcgcaaaca cggactttac gcaacattta tggcgaagcc aaaatttggt attgctggct
    10261 caggtatgca ctgtaatatg tccttgtttg atgcagaagg aaataacgcc ttctttgatc
    10321 caaatgatcc aaaaggaatg cagttgtcag aaacagctta ccatttccta ggcggtttga
    10381 tcaagcatgc ttacaactat actgccatca tgaacccaac agttaactca tacaaacgtt
    10441 tggttccagg ttatgaagcg cctgtttaca ttgcttgggc tggtcgtaac cgttcgccac
    10501 ttgtgcgcgt acctgcttca cgtggtatgg gaactcgtct tgagttgcgt tcagtggatc
    10561 caatggcgaa cccttacatt gctatggctg ttcttttgga agttggtttg tatggtattg
    10621 aaaataaaat cgaagcacca gctcctatcg aagaaaatat ctacatcatg acagcagaag
    10681 agcgcaagga agctggtatt acagaccttc catcaactct tcacaacgct ttgaaagctt
    10741 tgacagaaga tgaagtggtt aaagctgctc tcggagatca catctacact agcttccttg
    10801 aagccaaacg aatcgaatgg gcaagttatg caaccttcgt ttcacaatgg gaaattgata
    10861 attatttaga cctttactaa tatagaa
//
LOCUS       DAVLIK010000056        10844 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLIK010000056 DAVLIK010000000
VERSION     DAVLIK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.056"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            21..884
                     /locus_tag="VXE87_001774"
                     /pseudo
     CDS             21..884
                     /locus_tag="VXE87_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1267..1887
                     /locus_tag="VXE87_001775"
     CDS             1267..1887
                     /locus_tag="VXE87_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843276.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTCKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            1973..2416
                     /gene="tsaE"
                     /locus_tag="VXE87_001776"
     CDS             1973..2416
                     /gene="tsaE"
                     /locus_tag="VXE87_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0843277.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2406..2924
                     /locus_tag="VXE87_001777"
     CDS             2406..2924
                     /locus_tag="VXE87_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0843278.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVCHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            2932..3948
                     /locus_tag="VXE87_001778"
     CDS             2932..3948
                     /locus_tag="VXE87_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0843279.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4033..5289
                     /locus_tag="VXE87_001779"
     CDS             4033..5289
                     /locus_tag="VXE87_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0843280.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5344..6510
                     /gene="recA"
                     /locus_tag="VXE87_001780"
     CDS             5344..6510
                     /gene="recA"
                     /locus_tag="VXE87_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0843281.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6817..8187
                     /locus_tag="VXE87_001781"
     CDS             6817..8187
                     /locus_tag="VXE87_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0843282.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKQPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8563..9519
                     /gene="lytA"
                     /locus_tag="VXE87_001782"
     CDS             8563..9519
                     /gene="lytA"
                     /locus_tag="VXE87_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0843283.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(10152..10844)
                     /locus_tag="VXE87_001783"
                     /pseudo
     CDS             complement(10152..10844)
                     /locus_tag="VXE87_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT         3275 a         1877 c         2383 g         3309 t
ORIGIN      
        1 aggaaggttt attatcttta atgagtacac tcgcagagaa attcagattg aaaagaaaag
       61 agttgagact ctcccaacaa actcttgcag aaggaatttg tgaacaaagc cagattagta
      121 aaattgagag agggcatttc attccctccg cagacctttt gttcaaactc tctcaacgac
      181 ttgaagtacc attagattat ttttttaatg aacaaattga aattaaatct aacctctcta
      241 atttcaagca attgtctgct cgactattag acgatagaaa ttatgacgat ttggaatata
      301 tttatagaat agagattgaa cgaagtactt ttctaacact agaagaccga acttaccttg
      361 aatggattaa agctattatt gacttctatc aatatgacag taagtgtgag gcaatttctt
      421 cattggaaaa tatattatta aaagtctctt caaatactct gatttattta aaggcgttga
      481 atactctatc taatttctat tccttagtgg gtcgtgaaca agaatatgag gcaaactact
      541 ctcatttaat agagttgtat cagacaaaaa atttggacca tcaagagttt ttatttggct
      601 acatcagagt tcgttacaac tacgctcact acctagtatc aaaggaaaaa tataatgaag
      661 ccatctaaga agctcttgaa acgattgaac tctgtaaaca aagatagaca agctaccaat
      721 tggctcctct acttattctt gtaggaaatg ctggagccaa atttctagac agagaacaag
      781 tcaaaaatta ttatatagaa gcaagagagc tatgcaagat ttataacaat cctttaatgc
      841 tgatgaagat agaaaattat ttgaaggaac tagatgctgt ttagtttatc ttgatattgg
      901 agtgttactt aaacattaaa tagcctgtaa ggctgatagt tagattaata ctatcagcct
      961 tataattatg tgactctgag tccgtctcgc tccgtgaggt gcgagacaaa acaaccaccc
     1021 gtttgacgga ttttcatgat ttcaaattta tattcttcga aaatctcttc aaaccacgtc
     1081 agctctatct gcaatctcaa aacagtgttt tgagcaacct gtggctagct acctagtttg
     1141 atctttgatt ttcattgagt attagtctct agtgtttgtt tagcgtctta aagagacatt
     1201 tgagaagatt agaaacagtt ctctcttttc tcctagtata atgattggta ggaagggaga
     1261 gagaagatga aatcaatgag aatcttattt ttgttagctt taattcaaat cagtttgagt
     1321 agctgtttcc tatggaagga atgcatcttg tcctttaaac aaagtacagc ttttttcatc
     1381 ggaagcatgg ttttcgtttc aggaatctgt gctggagtaa attatcttta tacctgtaag
     1441 caagaagtcc atagtgtcct agccagtaag aagtcggtga agctttttta cagtatgtta
     1501 ctcttaatta atttgttagg agctgttctt gttttgtcag ataacttgtt catcaaaaat
     1561 acgctgcagc aagaattagt tgacttttta ttgccatcct tctttttcct atttgggcta
     1621 gatttgctga tttttttacc cttgaaaaaa tacgtgcgcg attttcttgc tatgctagac
     1681 agaaaaaaga cagtgttggt gactatttta gcaacacttc ttttcttaag aaatccaatg
     1741 accattgtct cacttctgat ttatattgga ttgggcttgt tttttgcagc ctatcttgtc
     1801 ccaaattcgg ttaagaagga agtttccttt tatggtcata ttttccgaga tcttgtattg
     1861 gtcattgtta cgctcatttt cttttagaga aagcctgttt tttatggatg ttatgatgat
     1921 aagtttagta ggaaaataga cacaaaagaa aagtttttgg tataataaga gtatgtacac
     1981 aaaaaatgaa gaagagttgc aagccttagg ggagcgtttg ggccatctat tagcaaagaa
     2041 tgatgtttta atcttaactg gagaactggg tgcaggtaaa acgaccttta ctaaaggact
     2101 tgcaaaagga ttacagattt ctcaaatgat taaaagtcct acctatacta tcgtgagaga
     2161 gtatgaaggt cgacttccac tttatcacct agatgtttat cgtattgaag gagatgctga
     2221 ttctatcgac ttggatgagt ttatctttgg tggcggcgtg actgttattg agtggggaaa
     2281 tctcttagga gatgccttgc cagatgctta tttagaattg gaaattctaa aagaagcaga
     2341 tggacgccgt ttaaattttc aggcaaaggg tttgcgtgct gagaaattgt tagaggagct
     2401 tcaatatgga gtatgaattg ctcattaggg aagcagagcc caaagatgca gctgaattag
     2461 tggccttttt aaatcgtgtg agtttggaga cagactttac cagcctagac ggagatggta
     2521 ttctcttgac tagtgaggag atggaaatat tcctcaacaa gcaagctagt tcggacaatc
     2581 agataacctt acttgcattc ttaaatggca aaattgctgg tattgtaaat attacagctg
     2641 accagcgtaa gagagtctgt catattggag atctcttcat tgtgattgga aaaagatatt
     2701 ggaataatgg cttgggaagt ttgttgctag aagaagcgat agagtgggca caagcaagtg
     2761 gcattctgcg tcgtctccaa ctgactgtcc aaactcgtaa tcaagcagca gtccatcttt
     2821 atcaaaagca tggctttgtc attgaaggta gccaagagcg tggggcatat atagaagaag
     2881 ggaaatttat cgatgtttac ttgatgggta aactgataga ttagtagaaa tatggttaaa
     2941 aaaattattg gaatggtgct agctttactt tctgtaactg tagtaggagt aggtgttttt
     3001 gcttatacta tttatcaaca agggacagaa accttagcta aaacctataa aaaaatcggc
     3061 gaagaaacca aggttattga agcgactgaa cctctaacca ttctgttaat gggagtggac
     3121 accggaaatg ctgaacgaac tgaaacttgg gtcggtagaa gtgatagcat gatcttgatg
     3181 acagtgaatc ctaaaacgaa aaaaacaaca atgatgagtt tagagcggga tattctgacg
     3241 cgcattgaat cagggaatgg tcaggctcat gaagcgaaac tgaactcagc atatgcagat
     3301 ggtggagcag agcttgctat agaaaccatt caaaaaatga tgaatatcca tattgatcgc
     3361 tatgtgatgg tcaatatgag agggttgcaa aaactagtgg atgcagtagg aggtattaca
     3421 gtcaataata tcctaggttt cccaatttct atcagtgacc aagaagaatt taatactatt
     3481 tctatcggtg ttggggagca acatattggg ggagaagaag ccctagtcta tgcacgaatg
     3541 cgttaccaag atcctgaggg ggattatggt cgtcaaaaac gtcaacgtga agttattcaa
     3601 aaagtcatgg aaaaagctct cagtttaaat agcgttggtc attatcaaga gattctaaaa
     3661 gctttgagtg acaatatgca gaccaatatt gatttgtctg caaaaagtat ccctaacttg
     3721 ctaggctata aagattcatt taaaaccatt gaaactcagc agttgcaggg tgaaggagag
     3781 atacttcaag gtgtttctta ccagattgtt tcgagagcac atatgttgga aatgcaaaat
     3841 atactccgac gttctttggg acaagaagaa gttactcagc ttgaaaccaa tgcggtttta
     3901 tttgaagatt tatttggcag agcacctgtt ggtgatgaag ataattaact tttgatacaa
     3961 ataaaaaaat caatcgtagg aaaattcctg cgattttttc aaaaaaatac gaatagatag
     4021 gtaggaggaa acatgaaagc agaaatcatt gctgttggaa cagagatttt gacaggacag
     4081 attgtcaaca ccaatgccca gtttttgtcg gaaaaactag ctgagattgg ggtagatgta
     4141 tattttcaga cggctgtagg agacaatgaa gttcgtctct tgtctttgct tgagattgcc
     4201 agtcaacgta gcagtctggt gattttgaca ggcggtttgg ggccaactga ggacgaccta
     4261 accaaacaaa ccctagctaa atttttaggg aaagcattag tctttgatcc tcaggctcag
     4321 gagaagttgg atatcttttt tgccctgcga ccagactatg cccgaacacc gaataacgaa
     4381 agacaagctc aaattgtaga aggagcgatt ccactgccaa acgaaacagg actggctgtt
     4441 ggaggaaaat tagaagtaga cggagtgacc tatgtcgtcc ttccaggtcc gccaagtgaa
     4501 ttgaaaccca tggtcttaaa ccaacttcta cccaagttga tgacagggag caagctgtat
     4561 tcccgagttc ttcgtttctt tgggattggc gagagccagt tggttacgat tttggctgat
     4621 ttaattgata atcagatcga tcctaccttg gccccttatg ccaagacagg agaagtcact
     4681 ctacgtctgt caacaaaggc tagcagtcaa gaagaggcga atcaagcgct ggatatcttg
     4741 gaaaatcaaa tcttggactg ccagactttc gaaggaattt ctttacgaga cttttgctat
     4801 ggttatgggg aagaaactag tttagccagc attgtggtag aagaactgaa aaggcaaggg
     4861 aaaaccatcg cggctgcaga gagtttaacg gcaggtcttt tccaagctac cgtggcgaat
     4921 ttttctggag cttcaagtat atttaagggt ggttttgtga cctatagctt ggaggaaaaa
     4981 tcaaggatgt tggatattcc tgccaagaat ttggaagaac atggtgtggt gtctgaattt
     5041 acagctcaga agatggctga gcaggcacga agcaagaccc agtctgattt tggaattagt
     5101 ttgaccggag tggcaggacc agatagccta gaaggacacc cagttgggac agtcttcata
     5161 ggcttggcgc aagagcaagg aactgaggtt atcaaggtta atattggagg cagaagccga
     5221 gcagatgtac gtcatattgc ggttatgcat gcctttaacc tagttcgcaa ggctttatta
     5281 agtgactaac ttttgatata atagtagata ggtctgagga tcattagaat gtaggagaat
     5341 agaatggcga aaaaaccaaa aaaattagaa gaaatttcaa aaaaatttgg ggcagaacgt
     5401 gaaaaggcct tgaatgatgc tcttaaattg attgagaaag actttggtaa aggatcaatc
     5461 atgcgtttgg gtgaacgtgc ggagcaaaag gtgcaagtga tgagctcagg ttctttagct
     5521 cttgacattg cccttggctc aggtggttat cctaagggac gtatcatcga aatctatggc
     5581 ccagagtcat ctggtaagac aacggttgcc cttcatgcag ttgcacaagc gcaaaaagaa
     5641 ggtgggattg ctgcctttat cgatgcggaa catgcccttg atccagctta tgctgcggcc
     5701 cttggtgtca atattgacga attactcttg tctcaaccag actcaggaga gcaaggtctt
     5761 gagattgcgg gaaaattgat tgactcaggt gcagttgatc ttgtcgtagt cgactcagtt
     5821 gctgcccttg ttcctcgtgc ggaaattgat ggagatatcg gagatagcca tgttggtttg
     5881 caggctcgta tgatgagcca ggccatgcgt aaacttggcg cctctatcaa taaaaccaaa
     5941 acaattgcca tttttatcaa ccaattgcgt gaaaaagttg gagtgatgtt tggaaatcca
     6001 gaaacaacac cgggcggacg tgctttgaaa ttctatgctt cagtccgctt ggatgttcgt
     6061 ggtaatacac aaattaaggg aactggtgac caaaaagaaa ccaatgtcgg taaagaaact
     6121 aagattaagg ttgtaaaaaa taaggtagct ccaccgttta aggaagccgt agttgaaatt
     6181 atgtacggag aaggaatttc taagactggt gagcttttga agattgcaag cgatttggat
     6241 attatcaaaa aagcaggggc ttggtattct tacaaagatg aaaaaattgg gcaaggttct
     6301 gagaatgcta agaaatactt ggcagagcac ccagaaatct ttgatgaaat tgataagcaa
     6361 gtccgttcta aatttggctt gattgatgga gaagaagttt cagaacaaga tactgaaaac
     6421 aaaaaagatg agccaaagaa agaagaagca gtgaatgaag aagttacgct tgacttaggc
     6481 gatgaacttg aaatcgaaat tgaagaataa gctgttaaag cagtggagaa atccgctact
     6541 ttttcgattt ttgattcaag tttttagatt atatatagta gcttgaaata agatatgaac
     6601 aactctatta ggaaagtcaa attaatttct agaaatgttt tagcagctac agcgtactat
     6661 tccaaactca accaactata atagatcgaa actagaatag tacatatcta cttctaaaac
     6721 attgttaaaa atcgatttga ctttccttat ttcattccgc tatatataag tttgctgttt
     6781 cttgtcgctc ctctggaaag ctgatataat agctttatga ataaaaaacg aacagtggac
     6841 ctgatacatg gtccgattct tccctcgctc ttaagcttca cctttccaat tttgctatca
     6901 aatatttttc aacagctcta taacactgct gatgtcttga ttgttggacg atttcttggt
     6961 caagaatcct tggctgcagt aggagcgacg acagcgattt ttgacctgat tgtaggtttt
     7021 acacttggtg ttggcaatgg catggggatt gtcattgctc gttattatgg ggctcggaat
     7081 ttcactaaaa tcaaggaagc agtagcagct acttggattt taggtgctct tttgagcatt
     7141 ctagttatgt tgctgggctt tcttggcttg tatcctctct tgcaatactt agatactcct
     7201 gcagaaattc ttcctcaatc ttatcaatat atttctatga ttgtgacctg tgtaggtgtc
     7261 agctttgctt ataatctttt tgcaggcttg ttgcggtcta ttggtgacag tctagcagcc
     7321 ctgggatttc tgattttctc tgccttggtt aatgtggttc tggatctcta ttttattacg
     7381 caattgcatc tgggagttca atccgcagga cttgctacca ttatttcgca aggtttatca
     7441 gcggttctct gcttttatta tattcgtaaa agtgtgccag aactcttgcc acagtttaaa
     7501 catttcaaat gggacaaaag cttgtacgca gatctcttgg agcaaggttt ggctatgggc
     7561 ttgatgagtt caattgtatc tatcggcagt gtgattttac agtcttctgt taatacattt
     7621 ggtgcagtga ttattagtgc ccagacggca gctcgacgca ttatgacctt tgcccttctt
     7681 cctatgaccg ctatttctgc atcaatgacg acctttgctt ctcagaatct aggagctaag
     7741 caacctgacc gcattgttca aggtcttcga atcggcagtc gtttaagtat atcctgggca
     7801 gtttttgttt gtattttcct cttttttgcc agtccagcct tggtttcctt cttggctagt
     7861 tcgacagatg gttacttgat agaaaatgga agtctctatc tgcaaatcag ttcagccttt
     7921 tatcccattt tgagcctctt gttgatttat cgcaattgct tgcagggctt ggggcagaag
     7981 atccttcctc tagtttctag ctttattgaa ctaatcggaa aaatcgtttt tgtggttttg
     8041 attattcctt gggcaggata taagggtgtt atcctttgtg aacctcttat ctgggttgcc
     8101 atgacagttc aactgtactt ctcactattc cgtcatccct tgataaaaga aggaaaggca
     8161 attttggcaa ccaaagtgca atcctagttg gatttactga ataaaatcca tttcctctag
     8221 tgaaaatcga aaaaacttgt gttctcttct ttagtttggt gttgaaaata gtttaacaga
     8281 cttttgactt cttttatatg atataataaa gtatagtatt tatgaaaagg acatatagag
     8341 actgtaaaaa tatacttttg aaaagctttt tagtttgggg tgttattgta gatagaatgc
     8401 agaccttgtc agtcctattt acagtgtcaa aatagtgcgt tttgaagttc tatctacaag
     8461 cctaatcgtg actaaaattg tcttctttgt aaggtagaaa taaaggagtt tctggttctg
     8521 gattgtaaaa aatgagttgt tttaattgat aaggagtaga atatggaaat taatgtgagt
     8581 aaattaagaa cagatttgcc tcaagtcggc gtgcaaccat ataggcaagt acacgcacac
     8641 tcaactggga atccgcattc aaccgtacag aatgaagcgg attatcactg gcggaaagac
     8701 ccagaattag gttttttctc gcacattgtt gggaacggtt gcatcatgca ggtaggacct
     8761 gttgataatg gtgcctggga cgttgggggc ggttggaatg ctgagaccta tgcagcggtt
     8821 gaactgattg aaagccattc aactaaagaa gagttcatga cggactaccg cctttatatc
     8881 gaactcttac gcaatctagc agatgaagca ggtttgccga aaacgcttga tacagggagt
     8941 ttagctggaa ttaaaacgca cgagtattgc acgaataacc aaccaaacaa ccactcagac
     9001 catgtggatc cataccctta cttggcaaaa tggggcatta gccgtgagca gtttaagcat
     9061 gatattgaga acggcttgac gattgaaaca ggctggcaga agaatgacac tggctactgg
     9121 tacgtacact cagacggctc ttatccaaaa gacaagtttg agaaaatcaa tggcacttgg
     9181 tactactttg acagttcagg ctatatgctt gcagaccgct ggaggaagca cacagacggc
     9241 aactggtact ggttcgacaa ctcaggcgaa atggctacag gctggaagaa aatcgctgat
     9301 aagtggtact atttcaacga agaaggtgcc atgaagacag gctgggtcaa gtacaaggac
     9361 acttggtact acttagacgc taaagaaggc gccatggtat caaatgcctt tatccagtca
     9421 gcggacggaa caggctggta ctacctcaaa ccagacggaa cactggcaga caagccagaa
     9481 ttcacagtag agccagatgg cttgattaca gtaaaataat aatggaatgt ctttcaaatc
     9541 agaacagcgc atattattag gtcttgaaaa agcttaatag tatgcgtttt tatcctctag
     9601 tcacttgatt tgtttcaggt ggttttttag tatagtagaa tgaaacgaga acaggacaaa
     9661 ttgatcagga cagtcaaatc gatttctaac aatgttttag aagcagaagt gtactattct
     9721 agtttcaatc tactatagtt aaatctgcgg tcaagtctac tggtgaatct atgattgtaa
     9781 tactcttcca aaatctcatc aaccacgtca gtcttgcctt gcagtctgta tcttactgac
     9841 caagctagtg atggatttag aataggtgat ttggagcgtc ctattggcta ggaaatgctg
     9901 ctcatagtcc tttgctgagg ctagggtgtt tcaacattca acactcaact ggttgatcta
     9961 gttgatagga agggaattac tataaaatac tcaggcttcc atcatatttt ttgaaacgat
    10021 tgtgtaatca aaatgtacca atattgtagt attggtacag aagatgttgt gaatggataa
    10081 atatatcata actgctgtct caaaaagatt tcatatgtct gtgcatatat aatagacttc
    10141 ctgcgaaacc aaaatcctag ttcatgattg ataataccag cactcaaatt cattcgtaat
    10201 ccgaagcgtt tacgatgatt tcgataggtt gttgaaatca ttttaaacgt ttttactttg
    10261 gcaaagatgt tctcaacctt gcttctctcc ttggatagcg catggttaca ggctttatct
    10321 tcaactgtta gtggcttgag tttgctggat ttacgtggag tttgtgcttg aggatatatc
    10381 ttcatgagcc cttgataacc actgtcagcc aagattttac cagcttgtcc gatatttccg
    10441 cgactcattt tgaacaactt catatcatga caatagttca cagtgatatc caaagaaata
    10501 attcttcctt gacttgtgac aatcgcttga gccttcatag cgtagcattt ctttttacca
    10561 gaatcattcg ctaattgttt ttttagggcg attgatttgt acttccgtcg catcaatcat
    10621 taccgtgtcc tcagaactga gaggagttct tgaaatcgta acaccacttt gaacaagagt
    10681 tacttcaacc cattggctcc gacggattaa gttgctttcg tgaataccaa aatcagccgc
    10741 aatttgttca taagtgcggt attctcgcac atattgaaga gtggccataa gaaggtcttc
    10801 taggcttaat ttaggttttc gtccaccttt tgcgtgttta agtt
//
LOCUS       DAVLIK010000057        10786 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLIK010000057 DAVLIK010000000
VERSION     DAVLIK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10786
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.057"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..932)
                     /gene="lytB"
                     /locus_tag="VXE87_001784"
     CDS             complement(<1..932)
                     /gene="lytB"
                     /locus_tag="VXE87_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0843284.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGK"
     gene            complement(974..1960)
                     /locus_tag="VXE87_001785"
     CDS             complement(974..1960)
                     /locus_tag="VXE87_001785"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0843285.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1923..2723)
                     /locus_tag="VXE87_001786"
     CDS             complement(1923..2723)
                     /locus_tag="VXE87_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0843286.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2973..3353)
                     /locus_tag="VXE87_001787"
     CDS             complement(2973..3353)
                     /locus_tag="VXE87_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0843287.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3411..3770)
                     /gene="rplT"
                     /locus_tag="VXE87_001788"
     CDS             complement(3411..3770)
                     /gene="rplT"
                     /locus_tag="VXE87_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0843288.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3822..4022)
                     /gene="rpmI"
                     /locus_tag="VXE87_001789"
     CDS             complement(3822..4022)
                     /gene="rpmI"
                     /locus_tag="VXE87_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0843289.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(4055..4585)
                     /gene="infC"
                     /locus_tag="VXE87_001790"
     CDS             complement(4055..4585)
                     /gene="infC"
                     /locus_tag="VXE87_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0843290.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4601..4732)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4893..6077)
                     /locus_tag="VXE87_001791"
     CDS             complement(4893..6077)
                     /locus_tag="VXE87_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0843291.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVNLNWSMGMVLLPCLIIFLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(6081..6668)
                     /locus_tag="VXE87_001792"
     CDS             complement(6081..6668)
                     /locus_tag="VXE87_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843292.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6701..6889)
                     /locus_tag="VXE87_001793"
     CDS             complement(6701..6889)
                     /locus_tag="VXE87_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843293.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHGHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(7068..9308)
                     /locus_tag="VXE87_001794"
     CDS             complement(7068..9308)
                     /locus_tag="VXE87_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0843294.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GYLNTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9292..9942)
                     /locus_tag="VXE87_001795"
     CDS             complement(9292..9942)
                     /locus_tag="VXE87_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV0843295.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVHK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEESVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            complement(10010..10579)
                     /locus_tag="VXE87_001796"
     CDS             complement(10010..10579)
                     /locus_tag="VXE87_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0843296.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGKFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMYQHEKGRIVTRVHYVLTKEDYFANK"
BASE COUNT         3160 a         2407 c         1913 g         3306 t
ORIGIN      
        1 attttgccat caaacttgag gtaaaaccaa gattccttat cccaaatcca ttcattggct
       61 gccatgtagc caccggattt gaagtagtac caagcttgac tatgagaatc gtagacccat
      121 tctttttcag ctattttccc atcaaatttg agataaaacc aagattcctt atcccaaatc
      181 cattcattgg ctgccatgta gccaccggat tttagataat aatagtgacc attctcgaaa
      241 atccattctt tatcagcata gtttccattt tctttgatgt aaaaccaaga ttggtattgt
      301 ttgtcaaaaa gccaaccttg ctgtactttg gcaccactag cattcacata agcttgatta
      361 atccactgac ttgtcagtag ataaccaccg gatttgaaat aatagtcctt ccctttaatt
      421 tggagccatt ctttctctgc gtgctgtcca tctgctttga tataaaacca agcatcgtat
      481 tgagaatcat agacccagtc ttctattact ttggcacctg ttgcaccaac ataggaagtt
      541 cctacccaag catttctttt catctttcca tcttggtcaa gataataaaa ggctcccttg
      601 tcttctaccc attctgattt ggccatatag ccaccagatt tgaggtaaaa atagtcgtca
      661 ccttgcttta gccattcatt ttcagcatag ttagcatctg cttttatata gaaccaagat
      721 tgataatgag tatcaaaaac ccactcattc gctgcttgac tgccatcttc tttcagatac
      781 tgttttcctt gccaagtacc atcactagcc attgcaccct ctggactagc taagaaaaat
      841 agcagagcta aaaaaataaa tcttactttc ttcattaacc ttcttcctct gttcttattt
      901 attttattgt accaaaattc tcctaaattc atattacaaa ctaataaaaa atcaagaaca
      961 gattgattgt agtttacctc agagactctt ttacttcctg acggagttct tccagactgc
     1021 taataccgta tttatccatg acttttggta aattttcgat gatgtcaggg caggcataag
     1081 gattggtaaa gttagctgtt ccaactccga tagcagatgc cccagccaga tacatttcta
     1141 gggcagcttc agccgaatcc actcccccca ttccaatgat aggcaggtct gttgtttggg
     1201 ctacttggcg gatgagtttg agggctactg gaaagactgc tggacctgac attccacctg
     1261 ttccattggc caagattggt tttctggttt tgaggtcaaa gcgcattcca accagagtat
     1321 tgatcatggt caagccactt gctcccgcat cttctgcagc ttttgcgaca gtaacgatat
     1381 cggtcacact cggggttaat ttgacataaa ctggcacttc tgaggcttcc acagctgctt
     1441 tcaccacatc ataagccaaa tctggatctt gaccaatcaa aagtccatga ttacagtggt
     1501 caacattggg acaagaaata ttgagctcga tagcttttac attagttgcc ttggaaatcc
     1561 catgagaaac agctgcatac tcttgttttg aaaaaccagc tacattggca ataataggaa
     1621 gatttggata ttctctttcc agccaaggta gcttttcagc caaaacaacc tctaaaccag
     1681 gattttgcaa gccaattgca ttgagcatac cagcaggcgt ctctgccact cttggagttg
     1741 gatttccaaa acgtggttca agggttgtcg ccttgatcat aatagaacct aaaaggttta
     1801 aatcatagta cttggcatac tcttgtccaa aaccaaaaca acctgatgct ggaataatcg
     1861 gatttttcaa atccaaacca ggtagagaca cttgtaatcg atttgtagtc ataattttct
     1921 ccttataata caactgttcc tgtgcggaaa acaggaccat cttcacagac gcgttggctg
     1981 accgtctcgc tttctggtac ttttagaaca caggcatagc aagctcccat cccacaagcc
     2041 atacgagatt ccagagataa ataggctctt gggtgatcat caaaggtttg attgatatac
     2101 ttcatcattc ctggagcccc acacgagtaa acagcatcaa actgactatc taaatcattg
     2161 ataacaacgg aaacatttcc cttgatgcca taagaaccat catctgtcgt tacaaagacc
     2221 tgaccatact gagccaattc cgttttcaaa ataacagcat ccttattagc aaaaccgagg
     2281 actgtcacta ctttcactcc acgttcatgc aattccttgg ccacctcaag caagggtgga
     2341 acaccaatcc caccaccaac aaggagaacc tgattctgct catcaaggtc agacaagtca
     2401 aaaccatttc cctgaggccc catcacatca agagtgtctc cctgacttaa ggttgaaaaa
     2461 attgcagtcc cagctccctc aatccgataa atgaggtgac actgcttgtt tgccttgtca
     2521 atagacgaaa ttgaaatagg acgacgtaaa agatgggcat cgtctggtac acgcagatga
     2581 agaaattggc ctgctcgcat ggcttcaacc atttctcctt ctaggactaa ttcaaagatt
     2641 gctggcgcga tttcctcttg tgcaaccacc ttcatggttt ccaaccgaat gacacccaaa
     2701 cgcttcttac atgtgggatt cataactttt cctccttaaa ttttaagggg accagataaa
     2761 gaaaagacct tgctagtgca aggcctcagt taaaatcgta caacacaaga gagcacactc
     2821 aaaaagtctc ctctagaaaa ttgcactatt cttttatctg acaccttgtg agtctctctg
     2881 gactcccctt aaaggttgaa tttttattag tatactcttt cagctaaaaa aagtcaagta
     2941 gaaaacgaat attctactta acttgcacga aattattttt cacgaatgac ttcgacctta
     3001 tatccatcag ggtctttgac aaagtaatag tttggtgtag ttcctggtag accatttggc
     3061 tcagtcactt catagccttt tgcactgtgt tcttgatgaa gtgcctcaag atcaggtgta
     3121 ctgagggcga tatgggcaaa cccatcacca accacatacg gaccgtgatc gtagttataa
     3181 gtcaactcca actcataatc atcaccctca agacctagat agacaatcgt gaaggcatgg
     3241 tctggaaaat ctctgcgacg caattcttta aaaccaaaag catcttgata aaatgcgatt
     3301 gatttttcaa gattttctac tcgtaagcaa gtgtgtagca tttttgaagc catatctttc
     3361 tcctttattt ttaaaaagac tggacaatcc tgttccagtc tcatcagttg ttatttacca
     3421 agttttgctt tagctgcatc tgcaagagct gtgaaagcta ctgcatcgtt aacagccaag
     3481 tcagcaagca ttttacggtt aacttcgatc tcagccaatt tcaaaccatg catcaattgt
     3541 gagtatgaaa gtccgttcat acgagctgcc gcattgatac gagtaatcca caatttgcgg
     3601 aagtcacgtt ttttctgacg acggtcacgg tatgcatagt agtaagagtt cattacttgt
     3661 tcttttgcag tacggaacaa gatgtgttta gctccatagt aaccttttgc taatttaaga
     3721 atacgtttac gacgtttgcg tgatacaacg ccacctttaa cacgtgccat gttttatttc
     3781 ctccaaatat ttcctagaat tgtttactta cagtcaagct attatttcaa gcgagtaagc
     3841 attgctttga tacgtttgta atctcctgaa tgcaccatag atgctttacg aagatgacga
     3901 cgttgtttct tagtttttcc gtggaaacgg tgagaagtgt aagcacggaa acgtttaagt
     3961 ccaccagaac ctgtacgttt gaaacgttta gctgatgcgc ggtgtgtttt ttgttttggc
     4021 atgatttttt ctcctttatt taactttctg acaattattt tttgtcagtc gctggcgcca
     4081 attgcatgaa catttgacgt ccatccattt tagcacgttg ttcgatgatg gcaatatctt
     4141 gagttgcttc agcaaactcg gctaaaactt ttgcaccaat ctctttatgg gtaatcatac
     4201 gacccttaaa gcgaatagat accttaactt tatttccttt ttcaaggaac ttacgtgcat
     4261 tacgaagttt tgtatcaaag tcacccttgt caattgttgg acttagacga acttctttca
     4321 cagtaacaac gctttgtttt ttacgttgtt ctttttgctt cttctggtac tcaaatttga
     4381 acttaccgta gtccataatt tttgcaacag gcggtttggc ttggggttga atcaatacta
     4441 ggtcaacatt agcgttatca gccaaagctt gcgcttcact gagtggcttg atgcctagct
     4501 gttctccctc aagaccaatc aagcgaactt cacgtacacg aatctcatca ttgatgaata
     4561 agtcttgctt tgctatggtt ttcacctctt ttgttttatt agagaaaaac aatagcggac
     4621 tcgtaaatat acaagcccgc acgttatgat agcgtttctt cgaaactttt catccgtagg
     4681 gccaggcaac ttaatgtcac aaggcgagaa gctctcactt ctgcttttct caacttttaa
     4741 atgataccaa gttttctagc tcttgtcaag ataaaaagtt atttttttga aaagtttgtg
     4801 tttgtatttt ggtttggttt tcgaatcaaa aagagagaat caagttgatt ccctctctat
     4861 gttagttttt ccttaacttc cttataagaa tgctaagacc tattaaaaac ttccttttta
     4921 cgtgaacttc cccagctttc aataaataga atccccacta gcaaaaagat aatcaggcaa
     4981 ggaagtaaga ccattcccat gctccaattt agattgacat tatcaatttg cttaggtaat
     5041 cttccagata aaatctccac tgaacgcaag taagtaaagg gaatcagatg tgcaatcctt
     5101 tgaagaggct gaatggtttg gatgccaaac aataagccaa caatcccaat gagtgaaaga
     5161 aagaggacag gcattttttg cttgaaaaag taagcaatca agtacacaac ttccacaatg
     5221 acgataaagg ctaagaaagc taagagcaag ccaggaaata atacatcttg tattttccca
     5281 atagttactt cttgattcac taagctataa attgggtagg gataatctaa ctgtccaaaa
     5341 ccacttatca gacttcccac tagaaaagaa aagccacaga ttccgataaa cagcacagtt
     5401 acatatccca ctccaactcc aagagaggat attgcaaatg tcacttttga aacaggatat
     5461 aagtgagctg tgtccagatg attttgatat ctttctgcaa atagttgtgt tagcataaaa
     5521 ataatcgcaa ccacaaacaa gcttgggatg ataacctcta aaatccagac aatctgatca
     5581 atcccgtggg tcggaaactc caaagtatgt gcttttatgt tcaagggata cagggcttgg
     5641 taaatcttcc gttcgcggtc aacccccatt tttaagccag agctagcagt cgggtcattt
     5701 gatacaaatt cataattctt ctcttcatct tgccactgca gatagtaggc ttctttccag
     5761 cgcccttctt ttagtaaagt tagaatttct gtctttcgcg tcaaaagatt tttttgcacg
     5821 tctaaattat ttttagcaaa ctggtattcc tccgagctgg tatcagacat ttgggagagt
     5881 ttctcttcat tttcattgat agccctctcg ttggctgcaa tgcgactttc caacctgctc
     5941 tccaagctgt gtgagtttgc agtctgacta tttaaataaa aggtaacacc gagtacagat
     6001 gcaaataaaa gtaagataat ccagtttaaa cgacttttga aaactttttt caataaaaat
     6061 agactaacat ctttcataaa ctaaacctct tctatctgcc cctgatgaat ggttactact
     6121 ctatcgcaga tatcaaccaa ctcttcctta tagtgggaac ttaaaagaac cagctgttct
     6181 tgtctatcga tttgtgctag cctatcaaaa aacttctgtc gataatactc gtctaagcca
     6241 tttgtaatct catccatgag ccagcatttg gcctgactga gaaaatacat agcaatcacc
     6301 aagcgttgct tcatgcctaa ggaatacttg cggatgggaa gactgatata gtcagccatt
     6361 tcccagtagg cgatttcatc tctcaagttt aggtctgact tccagatgtt ttttatgaga
     6421 cgaaggtagt ccatcccact taagtttcca tccagccatt caacgctctc ataataaaac
     6481 aaagaaggag gaactgcgat gtgtccacta ctaaggggaa gcaacttgct catagctcgg
     6541 aatagtgtcg tctttcccga gccattgata gcaagaaggc cataaatcct acccttttta
     6601 aaggtaaaat ccgcatcttg caagatgact tgtcgcgttt ttaaggtcac atgagtaagc
     6661 tgcaacatat ctagccctcc tttttctcac tctttaagaa ttaatagcct ccgctgtaat
     6721 agtttatgac ctcataacga ccgtagttcc agcctccgcc aactttatac tcagaatagc
     6781 tgtcataacg agaccatgac ggaatccaag catactgatg gccgtgatag ttggtactat
     6841 attcccaaac cgtattccaa tcatacttgt aacttttagt gactgtcaca gcagatacac
     6901 tggactgaag aagaccaata gattataaac taactaatta aacgattttt gctaattttt
     6961 aatgatttta tatcctcaat attgaatacg ttttcattat accattttta tcattattat
     7021 gcaacaaatt tttagtttat ttcactaatc tacaacattt atctttccta tcgaacactt
     7081 tcgattttcc aactatccaa ccccttaaag cgtatagctc cttgctggtc agttcggtaa
     7141 actttgctat tgataccttc cagtcgtgtc aatgtttcct gatgggggag tttcattcga
     7201 ttgctctttc caactgagat aagagtaagc tctggtttga gtttttctag aaaggctgga
     7261 cttgatgatt ttttattgcc atgttggcta gctttcaaaa catttacttt caagtctgga
     7321 tagtgcttca gcaagtcctt ctctcctttc tcctccaaat ttcccgtgaa gagaaattgc
     7381 ttatccaaga atttcccata cagaactagg gtatcatcgt gtcctccatc tcccattttc
     7441 cttggggata gaacttctaa ctgacttcca aaaatgggca agttctcccc tactgtcata
     7501 ctacgcacct ttgtttgagt cgcctgtagt tctaccacaa attgcttctg cttcaaactg
     7561 ccttttgata ctaaaatctc ccctacatgg aaagccttgg tcacctctaa caaatctccg
     7621 acatgttcct tgtccgtatt tgtcaaaatc agctggtcaa tcttagctac tcctcgactt
     7681 ttaagatagg gtatcaagct tctctgtgca ttgctggtcg tcatcttttc ttgccatttt
     7741 tcgattttct tataagattc tgccttacca cctacatcta tgagaatggt tttcccagtt
     7801 acatcccgta ggaaaatact ttctccttgc cccacatcca gcatggtgat ttcattttcc
     7861 agtggatact tggtaaggaa aaagagacct gtaatcaata aactcaatac tgttaatcct
     7921 ttaatgtttt tcctcaaatc atagaccaaa gccaaggaaa ttaacaataa gattaaaagc
     7981 catgcgttgg gttgaccaaa gacaagcggt ctccttgcca cctgcgagac caagcgaata
     8041 atgccctcta accattcaaa gataaagttc agctgaatga ctggatagag aaaggaaagg
     8101 acaaataaaa tagacaagag cggtaagaag gtcaagtcaa atagaaagga aaagacaaag
     8161 gtcaaaagga tagaccaagg ttgaaattcc gcaaaataga aggatagaat gggcaatatg
     8221 cccaaggaga tgactagact ttcactagca acagccttga gcccctcccc ttctttgctg
     8281 gtcatggtca ggataaaagc ataagcgcag gacaagactc ctcctgctgt caagaaaaag
     8341 tttggcatga caataaagag gacaagcacc gtcaaggcaa aattatccaa gcccttaacc
     8401 ccatgttgag ccagtagctt ttgcaagaga ctgcgaataa ccgatgctga aaatccagtt
     8461 agtcccgcat agataaggga aaagggataa gtcagccatt tcaacttttc ttgggtcaag
     8521 cccaatcgca agagaagttt cttaaatcca ttcatgaaaa aacctacctg catgccagat
     8581 agggcaaaga ggtggataat tcctagactg gaataaagct cattcatctc ctcaaagtcg
     8641 gtgttcagat atcccagcaa gagtcctgtc atgtaattgc gcatagggtc tggaaagtgc
     8701 gtcttaatcc aaaccacagc ctttcgacgt aaactggaca agttttctcc tatatcccaa
     8761 ctgccaatct tttgaagtga ctggattttt ttgatattga gagtctggta aattccctga
     8821 gtcttcagat aggcttggta attaaagcca ccaaaatttc tctgcccttc tggctccgaa
     8881 agcttccctt ctagtcctat ctcatgcagg tcggttaaag cttgaaaggc ttctttctcc
     8941 tcctcggact ggagtttata atagacttgg aaagcacgac cgttagactt gccacgaaag
     9001 gatagactat caccgttaac cttaatagtg tctggtaaaa tccgtaccct ttcaacagaa
     9061 tccaccaaat tttgactcac ttgactctgt tgccaatttt gaaaaacaaa ccaaaatcca
     9121 aagattccgc aaattattag aactttacca gcagatttcc acggaaattg gataaagaga
     9181 cagactagca gaaaaacaaa gcccaacaaa gcaagataag atgctgagaa aatagcgtaa
     9241 taaagccaaa gtaatagaaa actcaggtaa attaggggaa tagagaaatt cttaatccac
     9301 tgtaacatag tctttaagct tttctattgt tttgccacca atgccagaga ccttcttgag
     9361 ctcgtctact gacttgaact tgccatttgc ctcacgatgg tcgataatgt cctgagctcg
     9421 ttttcctccc agtcccttga cctgcttgag ttcttccaga ctggccttgt tgagattgac
     9481 cttcttttcc ttgcttattg aagaagctgt ccccaaacca gtctgttggc taactgattc
     9541 ttctccctta gtaggaacgt aaaccagagc ctcatcacta actttctgag ctagattgag
     9601 cgacttgctg tctgcttgct ctgtcaagcc accagcctta tgaacagcat cattgactcg
     9661 actacctaca ggcaagtcat aaatccctgg cgatttgaca gcacctttga catctactgt
     9721 gattagatct tgttcaaggg gttcttcctt ttcttccttg ttcacttcct tttcggatac
     9781 caaatccttg gaaacagctg cgacttcagc ctgcaaattc gtctctttga caggtgtttg
     9841 tggagctggt tttagcagga aaaatcctcc tacaagcaag cccagaccag tacagatgac
     9901 gatgatttta tactctttga ttttctcgat aattgcttcc atattttctc ctctcttaga
     9961 ttattcgtaa gaggaagaaa aaacagtcga aaaatttctt ttcaactgct tatttatttg
    10021 caaaatagtc ttccttggtc aagacataat gaactcttgt cacgattcgg cctttttcat
    10081 gctggtacat acaagcatat ggttctgcat gggaaaaacg cattcctgat ttctccatga
    10141 cctttcctga tgcgggatta gccttatcgt ataaagcaac taacttattc attcctatct
    10201 tctcaaaagc tagctcaatc acagcacgat tggtttctgt cgttaatcct tgattccaat
    10261 acgtttggtt gataatataa ccaatagcta ccttcttaag aacaggatca atcttgtgca
    10321 aatcaattgt tccgataaat ttgccattgc tttttagttc tattccccaa cgtcccaagg
    10381 gattagccaa gtagaactga gcaatgttat tcttggtttc ttccaagctt tgattggttg
    10441 gaaaagtgta acgtgtatta cccttgtccg aggcatagtc aaacattgct tccgcatcat
    10501 ccaaagttac aggtctaagc aataaacgct ccgtttctat agacggatac tgggcaagtt
    10561 ttacaaaaat tgattccata cttttccctc cattagaact tgattttcac tagtctagca
    10621 taaaaaaatt gggatgacaa gtttttcttg atttttgaag cggtttcata tacaatgaaa
    10681 ccgtcacatt tttgatttat gaactggaat gtgacaacca aaacaagacc gtcaattgaa
    10741 aggtaggtta tctcaatgtt aatcggaatc ccaaaagaaa ttaaaa
//
LOCUS       DAVLIK010000058        10761 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLIK010000058 DAVLIK010000000
VERSION     DAVLIK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.058"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            127..624
                     /locus_tag="VXE87_001797"
     CDS             127..624
                     /locus_tag="VXE87_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0843297.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            624..2279
                     /gene="dnaX"
                     /locus_tag="VXE87_001798"
     CDS             624..2279
                     /gene="dnaX"
                     /locus_tag="VXE87_001798"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0843298.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYTPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKSEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQIEKEVEESLIPEGFEFLADKVKVEED"
     gene            2307..2501
                     /locus_tag="VXE87_001799"
     CDS             2307..2501
                     /locus_tag="VXE87_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0843299.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2651..3421
                     /gene="sufC"
                     /locus_tag="VXE87_001800"
     CDS             2651..3421
                     /gene="sufC"
                     /locus_tag="VXE87_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0843300.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3449..4711
                     /gene="sufD"
                     /locus_tag="VXE87_001801"
     CDS             3449..4711
                     /gene="sufD"
                     /locus_tag="VXE87_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0843301.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLLGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4722..5948
                     /locus_tag="VXE87_001802"
     CDS             4722..5948
                     /locus_tag="VXE87_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0843302.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINACSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5935..6375
                     /locus_tag="VXE87_001803"
     CDS             5935..6375
                     /locus_tag="VXE87_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0843303.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDVVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6429..7841
                     /gene="sufB"
                     /locus_tag="VXE87_001804"
     CDS             6429..7841
                     /gene="sufB"
                     /locus_tag="VXE87_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0843304.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8072..9313)
                     /locus_tag="VXE87_001805"
     CDS             complement(8072..9313)
                     /locus_tag="VXE87_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0843305.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9416..10525
                     /locus_tag="VXE87_001806"
     CDS             9416..10525
                     /locus_tag="VXE87_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0843306.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLIWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         3198 a         1966 c         2335 g         3262 t
ORIGIN      
        1 taaaataggt tccataatat ctatagtgga tttacccact acaaatatta tagagcccaa
       61 aatcctttgt ttactaaaca agggattttt cttttgtctc tgctcctttt ttgatataat
      121 agttctatgt taaaatcaga aaaacaatca cgttatcaaa tgttaaatga agaattgtcc
      181 ttcctattgg aaggcgaaac caatgttttg gctaatcttt ccaacgccag tgctctcata
      241 aaatcacgtt ttcctaatac cgtatttgca ggcttttatt tgttcgatgg aaaggaattg
      301 gttttaggtc ccttccaagg aggtgtttcc tgcatccgta ttgcactagg caagggtgtt
      361 tgtggtgagg cagctcactt tcaggaaact gttattgttg gagatgtgac gacctatctc
      421 aactatattt cttgtgatag tctagctaaa agtgaaattg tggtgccgat gatgaagaat
      481 ggtcagttac ttggagttct ggatctggat tcttcagaga ttgaggatta cgatgctatg
      541 gatcgagatt atttggaaca atttgtcgct attttgcttg aaaagacaac atgggacttt
      601 acgatgtttg aggaaaaatc ttaatgtatc aagcacttta tcgaaaatat agaagtcaaa
      661 acttctccca gttagttggt caagaagttg tggctaagac tcttaaacaa gcggtggagc
      721 aagagaaaat aagtcacgct tatctttttt ctggtcctcg tggaacggga aaaaccagtg
      781 ttgctaaaat ctttgccaag gctatgaact gtcccaatca agtgggtggc gaaccttgca
      841 ataactgcta tatttgtcaa gcagtgacgg acggtagttt agaagatgtc attgaaatgg
      901 atgcagcttc taataatggg gtagatgaaa ttcgcgaaat tcgtgataaa tctacctata
      961 cgcctagcct tgctcgttat aaggtttata tcatagatga ggttcacatg ctgtctacag
     1021 gggcttttaa tgccctccta aagacgctgg aagaaccaac acagaatgta gtctttattt
     1081 tggccactac tgaattgcac aagattcctg ctactattct atcccgtgtg caacgttttg
     1141 agtttaaatc aattaagaca caggatatta aggaacatat tcactatatc ttagaaaaag
     1201 aaaatatcag ttctgaacca gaggctgtgg aaatcattgc cagacgggcg gaaggtggaa
     1261 tgcgggacgc cttgtctatt ttggatcaag ccctgagttt gacacaggga aatgagctga
     1321 cgactgctat ctctgaagaa attactggca ccattagcct atcagccttg gatgattatg
     1381 tggcggcctt gtctcaacag gatgttccca aagctttgtc ttgcttgaat cttctttttg
     1441 acaatggtaa gagcatgact cgttttgtga ccgatctttt gcactattta agagacttgt
     1501 taattgttca aacaggggga gaaaatactc atcatagttc agtctttgta gaaaatttgg
     1561 cacttcctca aaaaaatctg tttgaaatga ttcgcttagc aacagtgagt ttagcagata
     1621 ttaagtctag tttgcagccc aagatttatg ctgaaatgat gaccgtccgt ttggcggaaa
     1681 tcaagtccga accagcttta tcaggagcgg ttgaaaatga aattgctacg ctgagacagg
     1741 aagttgcccg tctcaaacaa gagctttcta atgtaggtgc ggttcctaaa caagttgcac
     1801 cagctcctag tcgaccagct acgggcaaaa cagtctatcg tgtcgatcgc aataaagtgc
     1861 aatctatctt acaagaggcc gtcgaaaatc ctgatttagc acgtcaaaat ttaattcgtt
     1921 tgcagaatgc ctggggagag gtaattgaaa gtctaggtgg gccggacaag gctctgctag
     1981 ttggttctca accggttgct gccaatgaac accatgctat tcttgctttt gagtctaact
     2041 tcaatgctgg tcaaactatg aaacgagaca atctcaatac catgtttggt aatatcctca
     2101 gtcaggcggc aggtttttca cctgagattt tagctatttc catggaggaa tggaaagaag
     2161 ttcgcgcagc cttttcagcc aaagccaaat cttctcaaat tgaaaaagaa gtagaagaaa
     2221 gcctgattcc agaaggattt gaatttttgg ctgataaagt gaaggtagag gaagactaaa
     2281 gaaagatttc atgatacaat aagtttatga ataaacaaca atttattatt atggcgctgt
     2341 ttacagctgc tgagacctat tttttcaatg aagcctggat gactggtcgc tatattatgg
     2401 cagccttttg ggcaatttta ctctttagaa atttccgagt cagttatgtg atgggcaaaa
     2461 tcgttgatgt catcgatcag cattttaata ggaaagacta gccctcagct tccagacaaa
     2521 atcaaagcct tttaggcttt tttttgttat actagaaaag tatatttata gaatttttgc
     2581 tctatttctg gggaaatcag acgtttttct agtaagtact gtaaaagttt tgaaaaagaa
     2641 aggaactatc atgtcagtat tagagatcaa agatcttcac gttgagattg aaggaaaaga
     2701 aattttaaaa ggggttaacc tgaccctgaa aacaggagaa attgccgcta tcatgggacc
     2761 aaatggtaca ggtaaatcga ctctttctgc cgctatcatg ggaaatccaa actatgaagt
     2821 aactaaaggt gaagttttgt ttgatggcgt aaacatcctt gagttggaag tggatgagcg
     2881 tgcgcgtatg ggacttttcc ttgctatgca atacccatca gaaatccctg gaattaccaa
     2941 tgctgagttt cttcgtgccg ctatgaatgc gggtaaagaa gatgatgaga agatttcagt
     3001 tcgtgagttt attactaagc tagatgaaaa aatggaattg ctcaacatga aagaagaaat
     3061 ggcagagcgt tacctcaacg aaggcttctc tggtggtgag aaaaaacgca atgaaattct
     3121 tcaacttttg atgttggagc caacatttgc tcttttggac gagattgact caggtcttga
     3181 tattgacgct cttaaagttg tgtctaaagg tgtcaatgcc atgcgtggtg aaggttttgg
     3241 tgctatgatc atcactcact accaacgtct tttgaactat atcacacctg atgtggtaca
     3301 cgtgatgatg gaaggtcgtg ttgtcctttc tggtggtcca gaattggctg cgcgtttgga
     3361 acgtgaagga tacgcaaaac tagctgaaga acttggctac gactacaagg aagaattgta
     3421 attccctcgt atcttttagg agaagtaaat gactagagaa aatattaaac ttttttcaga
     3481 aatgcacgct gaaccaagct ggttggctga tctccgtcaa aaagcttttg acaagattga
     3541 gactttggaa ttaccagtta ttgagcgtgt caaattccac cgttggaatc tgggtgatgg
     3601 aacgattaca gaaaatgagc catcagcaaa tgttccagat ttcacagctt tagatcatca
     3661 cttgaagttg gtgcaagtag gaactcaaac tgttttcgaa caaactccag ttgagttagc
     3721 tgaacagggt gttgtcttca cagactttca ctcagcttta gaagaaattc cagagctgat
     3781 cgaagaattc ttcatgtcat ctgttaagta tgatgatgac aagttggcgg cttaccacac
     3841 agcttacttt aacagtggtg ctgtactcta tattccagat aacgtagaaa ttacagagcc
     3901 aattgaagga attttctacc aagatagcga tagcaatgtg ccgtttaaca agcatattat
     3961 gattatcgct ggtaaaaatt ctaagattag ttatctggag cgtttagagt cacgcggtga
     4021 aggaagtgac aaagcaactg ccaatatcac agtggaagtg attgcacgtt ctggtgcgca
     4081 agtcaagttt gctgctatcg accgtctagg tgaaaacgtc actgcctaca ttagccgtcg
     4141 tggtaaatta ggcaacgatg caagtattga ctgggctatc ggtgtcatga acgaaggaaa
     4201 tgtcgttgct gattttgata gtgacttgct tggaaatggt agccatgcgg acctcaaggt
     4261 agtagcactt tcaagtggtc gtcaggtgca agggattgat actcgcgtga ctaactatgg
     4321 ttgcaactct atcggaaata tcctacaaca tggggttatc cttgaaaaag caactttgac
     4381 tttcaatggt atcggccaca tcatcaaggg tgctaaggga gcagatgccc aacaagagag
     4441 ccgtgttctc atgctttcag accaagcgcg ttcagatgct aacccaattc ttttgattga
     4501 tgaaaatgat gtcactgcag gacacgcagc gtctatcgga caagttgatc cagaagacat
     4561 gtattacctc atgagtcgtg gattggataa ggcaactgca gagcgtttgg ttgttcgtgg
     4621 tttccttgga tctgttatcg tggagattcc agtcaaggaa gttcgtgatg aaatgattgc
     4681 aactatcgaa gagaaattgt caaaacgcta aggggaagcc tatgttagat gtagaagcga
     4741 ttcgcaagga ttttccaatt ttagatcaga ttgtcaatga tgaacctctg gtctatctgg
     4801 acaatgctgc gacgacacaa aaaccactag tagttctgaa agctattaac agctactatg
     4861 aacaggacaa tgccaatgtt caccgtggtg tccatacctt agcggaacga gcgacagctt
     4921 cttatgaagc tgctcgtgaa accattcgta agtttattaa tgcatgctct acaaaggaag
     4981 ttctctttac cagaggaacg acaaccagcc ttaactgggt ggcacgcttt gctgaggaaa
     5041 ttctcactga gggagaccag gtcttgattt cagtaatgga acaccattct aatatcattc
     5101 catggcagga agcttgtcga aagactggag cagagcttgt ctatgtctat cttaaagacg
     5161 gtgccttgga tatggaggat ttgcgagcta aattgactga taaggttaaa tttgtttccc
     5221 tagctcatgc ctccaatgtt cttggtgtgg tcaatccgat taaggaaatc actcaattag
     5281 cccaccaagt tggggcaatc atggtagtgg atggtgctca atctacacct catatgaaga
     5341 ttgatgtcca ggacttggat ctggactttt tcgccttttc gggtcacaag atggctggtc
     5401 cgactggtat cggtgtcctt tacggcaaag aaaagtatct tgagcaaatg tctccagtag
     5461 aatttggcgg cgagatgatt gattttgtct acgagcaatc cgctagttgg aaggaattgc
     5521 cttggaaatt tgaggctgga acgccaaata tggcaggagc tattggactt gcgactgcag
     5581 ttgattatct ggaaaagatt ggtatggatg ccgttgaagc tcatgaacag gaattgattg
     5641 cgtacgtcta tccaaaactg caggcaattg agggattgac catttacggt tctcaggatt
     5701 tggctcaacg ttcgggtgtt attgccttta acctaggtga tctccatcct cacgatcttg
     5761 cgacggctct ggattatgaa ggagtggctg ttcgtgctgg tcaccattgt gcgcaaccct
     5821 tgcttcagta tttggaagtc ccagcatcag ctcgtgcaag tttttatatc tacaatacca
     5881 aggcagattg cgacaaacta gtcgatgccc tacaaaagac aaaggagttt ttcaatggca
     5941 ctttctaaac tagatagcct ttatatggca gtggtagcag accattcgaa aaatccacat
     6001 caccaaggga agttagaaga tgctgagcaa atcagtctca acaatccgac ttgtggggat
     6061 gtcatcaacc tctctgtcaa gtttgatgca gaggaccgtt tggaagatat tgcttttcta
     6121 aattcaggat gcacgatttc aactgcttct gctagtatga tgacagatgt cgttttagga
     6181 aaaaccaaac aagaaatttt agaactggcg actatttttt ctgaaatggt tcaagggcaa
     6241 aaagatgagc gtcaaggcca acttggagac gcggcattct tgtcaggtgt tgccaaattc
     6301 cctcaaagaa tcaagtgtgc aaccctagct tggaatgccc ttaagaaaac aattgaaaat
     6361 caagaaaaac agtaagacaa gtttcttttg tcttatgaat tattagaaat gaagaaagaa
     6421 aggatactat ggctgaagaa agagtagaac caaaaccaat tgaccttggt gaatataaat
     6481 ttggtttcca tgacgatgta gagcctgtct tatcgacagg aaaaggactc aacgaaggtg
     6541 ttattcgtga attatctgct gctaagggtg agcctgagtg gatgttggag ttccgtttga
     6601 agtcttatga aaccttcaaa aaaatgccca tgcaaacttg gggagcagac ttgtcagaga
     6661 ttgactttga tgacttaatc tactaccaaa aaccatctga caaaccagcc cgttcttggg
     6721 atgatgtacc tgaaaagatt aaagaaacct ttgaacgtat cgggattcca gaagctgaac
     6781 gtgcttattt agcaggggct tctgcccagt acgagtcaga agtggtttac cacaacatga
     6841 aggaagagtt ccaaaaatta ggtattatct ttacagatac agattccgca ctcaaggaat
     6901 acccagactt atttaaacaa tactttgcga agttggtacc gccgacagat aacaagttgg
     6961 cagccctcaa ctcagcagta tggtcgggtg gaacttttat ctacgtgcca aaaggtgtca
     7021 aggtagatat tccacttcaa acttatttcc gtatcaataa cgaaaatata ggtcagttcg
     7081 aacgtacctt gattatcgtt gatgagggag caagcgtcca ctacgtagaa ggatgtacag
     7141 caccaacata ttcaagcaat agcttacacg ctgccattgt agaaattttt gctttggacg
     7201 gagcttatat gcgttataca actatccaaa actggtctga taacgtctat aacttggtaa
     7261 caaagcgtgc taaggctcaa aaggatgcca ctgttgagtg gattgatgga aacttgggtg
     7321 ccaaaacgac tatgaaatat ccatctgttt accttgatgg agaaggagcg cgtggtacca
     7381 tgctctctat cgcctttgct aatgcagggc aacaccaaga cacgggtgct aagatgattc
     7441 acaatgctcc acataccagc tcgtctattg tgtctaaatc catcgctaaa ggtggaggaa
     7501 aggttgacta ccgtggacaa gtcaccttta acaagaactc taagaaatct gtttcccaca
     7561 ttgaatgtga taccattatc atggatgact tgtcagcatc agatactatt ccatttaatg
     7621 aaattcacaa ctcgcaagta gctttggaac acgaagccaa agtatctaag atttcagaag
     7681 agcaattgta ttatctcatg agccgtggat tgtcagaatc tgaggcaact gaaatgattg
     7741 tcatgggatt tgtagaaccc tttacaaaag aacttccaat ggaatacgca gttgagctga
     7801 accgcttgat tagctatgaa atggagggat cagttggata aaatttgatt ttatactctt
     7861 cgaaaatctc ttcaaaccac gtcagcatcg ccttaccgta tgtatggtta ctgacttcgt
     7921 cagtttcatc tacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagtta
     7981 gttctttgat tttgagtatt agatttactc aaaatcaagg attttgaaga tgaacttgta
     8041 tcaaaaaatc gcggtttaaa atcgcgattt tttataattt ctcgttaaca aagcggacaa
     8101 actgattcca ccaaactttt aagaagaagg ctttttcaat tttcttgtct gctaccattt
     8161 cgaaactagg gcgctctgtg gtgatgtaac cttgaccaat caagtccttg tcttcataag
     8221 tcaaatggcc aaccactgtt ccagcttcaa gtggtgctgg gattgctttg gaatcaggtg
     8281 tgaattgaac agattgggaa gattgattcc caacacgttc gattagatag atatcctctg
     8341 gagccactgc agttactgta tcttcttttc catcttgtac aggggctttg ctatcttgat
     8401 aggcatcgcc ttgttgaacg attttgcgaa gtgtaaatgt agaagaaata taatccatta
     8461 gggaagatgt agctgtaaat cgagcgtaag gattattgtc ttgatgatct gcatttaaaa
     8521 caactgtgat gactctcatg cctttttcga cagtagtacc aacaaaagac tctccagcct
     8581 tatctgttgt tcctgttttt agcccatcaa aaccaccacg gtaagcaggc ataccttcta
     8641 acatgtagtt ggttgaagtg attgtcatcc cagcaaaagt agaagaaggt tttttggtga
     8701 tttctaagac ttgtgggtat tttttgatga ggttgcgagc aacgatagcg acatcataag
     8761 cactaagctt attttcctca tcttttttag aacctgggta aatgttatcc cctagagttt
     8821 cattgttaag acctgtcgta ttgacaacag tggcatcctg aattccccat tccaagagtt
     8881 ttgcccgcat catatcgacg aaatcttttt ctgagccagc aattttctca gctagggcaa
     8941 tagcggcgct gttggcacta gataccagag ttgcttcaag caactcttcg acagtataat
     9001 tacgggcctc cataggaata ttactggctt cagaatttgt cgtcaattga taaggataat
     9061 cagaaatatc tacaggagtg gagagggtaa tacttccgtt ttccaaagct tcatagacca
     9121 gataaacagt aatcaatttt gttatggaag caatttcgac aggttgcgtt gcatccttct
     9181 catagagaat tttaccagta tttgcctcaa cagcaatcgc atgtttagcg gcaatggtaa
     9241 aatcttgagc aacagcagta gaagcacccc ctaaaagaga gacagttaac aaagttaaaa
     9301 atattttttt catagtagtc ttattctatc ataaagaaaa aaaatattct tgctttaata
     9361 attcatctgt taagcttttt gaaaatatgg taaaataaag tgagggaggt aactcatgtt
     9421 tcgtagaaat aaattatttt tttggaccac agaaatttta ctcttaacca tcatctttta
     9481 tctatggaga cagatggggt ctttgattaa cccttttgtt agcgtgctta atacaattat
     9541 gattccattt ttattagggg gctttcttta ttatttgaca aaccctattg ttactttctt
     9601 aaataaagtc tgtaaactca atcgtttgct tggtatttta attaccttgt gtactttgat
     9661 ctggggaatg gtcataggtg ttgtctatct cttacctatt ttgattaatc agttatctag
     9721 tttgattata tctagtcaaa ctatttatag tcgagtacaa gacttaatca tagacttatc
     9781 taattatcct gcgctccaga atttggatgt agaagctaca attcagcagt taaacttatc
     9841 ctatgttgat attcttcaaa atatcctaaa tagcgtatca aatagtgtgg ggagcgtctt
     9901 gtcagctctt atcagtactg ttttgatttt gattatgact ccagtttttt tggtttattt
     9961 cttattagat ggacataaat tcttgcccat gcttgaaaga acgattctaa agagggatcg
    10021 cttgcatatt gcaggcttat taaagaattt aaatgcgacg attgctcgct atattagtgg
    10081 agtttcgatt gacgcaatca ttataggttg tttggcttat attggctata gtattattgg
    10141 tttaaaatat gctttagttt ttgccatttt ttctggtgta gccaatttaa ttccttatgt
    10201 ggggccaagt attggtttga ttcctatgat catcgcaaat atattcactg atccccatag
    10261 actgctgatt gcagtgattt atatgcttgt tgttcagcag gtagatggca atatcttata
    10321 tcctcgaatc gtaggaagtg ttatgaaggt tcatccaatc acgattttag ttttactttt
    10381 gttgtcaagc aatatctatg gtgtagttgg aatgattgtc gcagtgccaa cctattctat
    10441 cttgaaagaa atttctaagt tcttatcccg tttgtatgaa aatcataaaa taatgaaaga
    10501 acgagaaaga gaattagcta agtaaaagtc aggagaaccc tgatttttct ttactggaag
    10561 tggcctttag attagaagac tgaaaataag ttaaagtctt aaactaattt tcacagctaa
    10621 gaatagtaga agttaatctg ataaaaatcg aaaaaaccag tggaattccg tgtcagggta
    10681 agttccactg gttttcatag tctattaaag ttcgaatgaa acctatttat agtatattga
    10741 aactagaata gtacacctct a
//
LOCUS       DAVLIK010000059        10726 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLIK010000059 DAVLIK010000000
VERSION     DAVLIK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.059"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..658
                     /locus_tag="VXE87_001807"
                     /pseudo
     CDS             1..658
                     /locus_tag="VXE87_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            558..1004
                     /locus_tag="VXE87_001808"
     CDS             558..1004
                     /locus_tag="VXE87_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0843307.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTRKPAHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1141..2445)
                     /gene="eno"
                     /locus_tag="VXE87_001809"
     CDS             complement(1141..2445)
                     /gene="eno"
                     /locus_tag="VXE87_001809"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0843308.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2609..3055
                     /locus_tag="VXE87_001810"
     CDS             2609..3055
                     /locus_tag="VXE87_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0843309.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3052..4167)
                     /locus_tag="VXE87_001811"
     CDS             complement(3052..4167)
                     /locus_tag="VXE87_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV0843310.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     VSGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGILDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4176..4505)
                     /locus_tag="VXE87_001812"
     CDS             complement(4176..4505)
                     /locus_tag="VXE87_001812"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV0843311.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4450..4821)
                     /locus_tag="VXE87_001813"
     CDS             complement(4450..4821)
                     /locus_tag="VXE87_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0843312.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4880..6313)
                     /gene="glgA"
                     /locus_tag="VXE87_001814"
     CDS             complement(4880..6313)
                     /gene="glgA"
                     /locus_tag="VXE87_001814"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0843313.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6310..7449)
                     /gene="glgD"
                     /locus_tag="VXE87_001815"
     CDS             complement(6310..7449)
                     /gene="glgD"
                     /locus_tag="VXE87_001815"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0843314.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLSFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7439..8581)
                     /locus_tag="VXE87_001816"
     CDS             complement(7439..8581)
                     /locus_tag="VXE87_001816"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0843315.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8571..10499)
                     /gene="glgB"
                     /locus_tag="VXE87_001817"
     CDS             complement(8571..10499)
                     /gene="glgB"
                     /locus_tag="VXE87_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0843316.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKNFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNPKGVENEK"
BASE COUNT         3268 a         2352 c         1902 g         3204 t
ORIGIN      
        1 ccagacgctt atttgactga aatagcttct gactttggct gtcatccaac taccatccac
       61 tatgcgctca aagctatggg ctacactcga aaaaaagaac cacacctact atgaacaaga
      121 cccagaaaaa gtagccttat ttcttaagaa ttttaatagt ttaaagcacc tagcacctgt
      181 ttagattgac gaaacaggat tcgatactta tttttatcga gaatatggtc gctcattaaa
      241 agatcagtta ataagaggca aagtatctgg aagaagatat cagaggattt ctttggttgc
      301 aggtctaaca aatggtgagt taatcgctcc aatgacttac gaagagacga tgacgagcga
      361 cttttttgaa gcttggtttc agaaatttct cttaccaaca ttaaccacac catcggttat
      421 tattatggat aatgcaagat tccatagaat ggggaagaat gtaagattcc atagaatggg
      481 gaatctagaa cttttatgcg aagagtttgg gcataaactt ttacctcttc ctccctactc
      541 gcctgagtac aatcctattg agaaaacatg ggctcatatc aaaaagcacc tcaaaaaggt
      601 attaccaagt tgcaatacct tttacgaggc tcttttgtct tgttcttgtt tcaattgact
      661 atataaattg tctaagcgaa acaaccgata agaattggca caaaagcgac cgtatttttg
      721 ttaccaatac aagaaaacca gctcatagtt ctatcttgag taagtctctc cagcgagcaa
      781 acgaacgcct taaaaaacca attcccaaac atctgtcccc tcacatcttc agacacacca
      841 ctattagcat cttatcagaa aataaaattc ctttaaaaac aatcacggac agggttggtc
      901 attccgactc tgaagtcact acttccatct acacccacgt cacaaagaac atgaaagatg
      961 aagcaatcaa tgtactggat aaagttatga aaaagatttt ttaaaagttt tgtccctttt
     1021 ttgtcctcta aatacaaaaa tagcccttcg gataaaatcc gaggggctag aaacgttgtt
     1081 aaatcaacgg ccgaactttt gaatttcatg gttcgggata aaatagttca ctgaactatt
     1141 ttatttttta aggttgtaga atgatttcaa tccacgatat tcagctactt caccaagttg
     1201 gtcttcgata cgaagcaatt ggttgtattt agcgatacgg tctgtacgtg aaagtgaacc
     1261 agtcttgatt tgtcctgcgt tagttgcaac tgcgatatca gcgattgttg aatcttcagt
     1321 ttcacctgaa cggtgtgata caacagcagt gtaaccagct tctttagcca tttcgatagc
     1381 ttcaaaagtt tcagtaagag taccgatttg gttaactttg ataaggattg agttagcagc
     1441 accttcttgg ataccacgtg caaggtagtc agtgtttgtt acgaagaagt cgtcaccaac
     1501 aagttgtact ttcttaccaa gacgttcagt aagagctttc caaccatccc agtcgttttc
     1561 atccatacca tcttcaatag tgatgattgg gtatttgtta accaattctt caaggtagtc
     1621 gatttgttct gcagatgtac gaacagcagc accttcacct tcaaatttag tgtagtcgta
     1681 aactttacgt tctttatcgt agaattctga tgaagcacag tcaaatccga taaatacgtc
     1741 tttacctggt acatatccag cagcttcaat cgcagcaagg atagtttcaa caccatcttc
     1801 agttccttcg aaacgaggag cgaatccacc ttcgtcacct acggcagttt ccaaaccacg
     1861 tgatttaagg attttcttaa gagcgtggaa gatttcagca ccgtaacgaa gggcttcttt
     1921 aaatgttggc gcaccaactg gcaagatcat gaactcttgg aaagcgattg gagcgtcaga
     1981 gtgagaacca ccgttgatga tgttcatcat tggagttgga agaactttag tgttgaatcc
     2041 accaaggtag ctgtaaagtg ggatttcaag gtagtcagca gcagcacgag ctacagcgat
     2101 agacacaccg aggattgcat tcgcacccaa tttacctttg ttaggagtac cgtcaagtgc
     2161 gatcatagca cggtcaatag cttgttgatc acgtacatcg tagccaatga tagcttcagc
     2221 aatgatgttg tttacgttgt caacagcttt ttgtgtacca agaccaccgt aacgagattt
     2281 gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta gaagctcctg atggaaccat
     2341 accacgtccg aaagcacctg attcagtgta aacttctact tcaagtgttg ggttaccgcg
     2401 tgagtctagg acttcgcgag cgtaaacatc agtaataatt gacatttttt actctcctta
     2461 tgagttaaat tttttacacc tctataatac cttaaaaccc ctcctttttc aagaaaaaac
     2521 gttatctttg tgcaactttt ccttaacttt ataaagtaat cgctttcttt tgtctgtttt
     2581 attctaactt ttatgatata ctgttttcat gacagattta tcaaaacaat tacttgaaaa
     2641 agctcatggt gggttaaaaa taaatccgga tgagcaaaga cgctatcttg gtacttttga
     2701 ggaaagagtt cttggatatg tagatattga cacagcaaat agccctcagt tagaaaaagg
     2761 ctttttattt attttagaaa accttcagga aaaagcagag ccactatttg tgaagatttc
     2821 accaactatc gaatttgata agcaagtttt ctacttaaaa gaagcaaaag aaactgatag
     2881 tcaagccacc atagtatctg aagagcatat tacttctcct ttcggcctgg ttattcatag
     2941 caatgcacca gttcaagtag aagaaaaaga ccttcgactt gcttttccaa aactttggga
     3001 agttaaaaag gaagaaccag ccaaaacatc cttatggaag aaatggttta gctaaatctt
     3061 gcacatattt aataagtgcc caatattggc agccgtgcgc tccagataga gactggcatt
     3121 tttcaaacta tcttctaaag gttcactttt ctccaaaata gaaaagacag cttggatatt
     3181 ttcaaatggt aggggaggta aatcttcagc aagactaccg caaatagcaa taacaggaac
     3241 tccaacaggg gttctttttg caacacctat aggcgctttc ccagcaaagc tttgactgtc
     3301 aagtattcct tctccaacaa caaccaagtc agcatctgaa actttcttat caaagttgat
     3361 taagtccaag caggtatcaa ttccagacac gatacttgcc tgagcaaagg cacacaaacc
     3421 accagcaagg cctccacctg ctcctgctcc tttaatttct aatgttgcag gtgagaattt
     3481 ttcataaaaa tcttggatcg cctgatctac gactgcaaac atagtcggat gtagaccttt
     3541 ttgattgcca aaagtgtaag tcgcaccttg atgaccacat aagggactca cgacatctgc
     3601 tagaatatga atttgaacac cttcaggaat tttatagcaa ttttctgttg aaacagaagc
     3661 taagtttaat aaggattgac cggaaacagg caagacattt ccatccctat cataaaattg
     3721 ataacctaaa ccagcagcaa tccccagtcc tccatcatta ctggccgtgc caccaacacc
     3781 gatataaata tctttaatcc ctttagaaat gagatggaga atcaactctc caataccaca
     3841 agtttggatt tgaagtggat ttcgtttctc tagcggaatt tttccaagac caaccaagtc
     3901 agctacttca aatagtgcca gttccccttt ttgaaaatag cgcatggctt ctttttgtcc
     3961 aaaagggtct gtcacttgga tccatttttc ttttaggtca agagaatgtc ggatagcatc
     4021 tacagtacct tctcccccat caccaacagg gcagaggaga cattctacat ctgctatcga
     4081 ttgttggaag cctcttttta ttgcttcagc tacctgttga gctgtcaagc tttccttaaa
     4141 cgaatccggt gcaattacaa tcttcatatt ttccctcatt ctaaacagtc aatcaaagga
     4201 agaacttcta aaaaatccct cttgtcaaca tgatgtggta tttctttttt gagcacttct
     4261 ttggcacaaa aggcgattcc taactccgcc gacttcaaca ttaatagatt attgacccca
     4321 tcaccgattg ccaccgttct ttctttagaa agttttagtt tctttctcca tttttccaga
     4381 gtttcttttt tgacctgggg acttataatt tgtccaacta attttcctgt taaaagacct
     4441 tctttgactt caagctggtt ggcagtgaaa taggcaatac caagggattt tgctaatctc
     4501 tccaactatt ggtgtaaatc caccagacac cagaccaact aggatgccat tcttttggag
     4561 aatagagatg aactctggga catttagcga tagatgaatt gagttgaaga cgttatcaaa
     4621 gaccaaaata ggaagacctt ccaacaagga cactcttttt cttaaactgc tttcaaagac
     4681 caactctcct cgcattgctc gacttgtaat ctgcgaaatt tccgcctcat gacctgcctc
     4741 tctccctaaa agatcaatca cttcttctag gattaaggtt ccatctacat ccaaaacaca
     4801 caagcctttt acttgagaca tcagttctcc tctctaaaca gcctaaaaat cgtatgaagt
     4861 catcatacga ttttatctat taattaacta aactatggta caagtcaagg tatgacttgc
     4921 aggctgtatc ccatgagaag tcactctcca tagcttgttt ttgtaggttt ctccaaatgt
     4981 ctggatggtt tctatacaag tccaatgctg tttggaaagt ccaatttaac caataaggag
     5041 atagattgtc aaagctaaag ccagtaccgc ttccttcgat tggattgaaa gcgcgaactg
     5101 tatctcgcaa gcctccaact tcatggacca atggcaaggt tccataacgc atagccatca
     5161 tttgagacaa gccacacggt tcaaaacgac ttggcatgag gaagaggtca caagcagcgt
     5221 agatttcctg agcaagtttg acatcaaaag tgatatttgt tgatagcttg tctgggtaaa
     5281 tctgagcaaa ccatgagaaa gctccttcaa aggctggatc gccagttccc aaaagaacaa
     5341 tctgaacatc ttcttgcaag atatggtgaa gactttcgac caccacatca aaaccttttt
     5401 gacgtgtcaa acgagaaaca attcccacca gtggaacgtc tgctctaaca ggcaagccaa
     5461 ctctttcttg caattttgcc ttatttttgg ctttcccaga caaatcttcc tgattgaaat
     5521 gatagtctaa aagagcatcc gtctgaggat tataaagatc agcatcaatc ccattcacga
     5581 taccagatac tttaccagac tccattttaa gaatctgatc caaattacat ccaaactgac
     5641 tagtcataat ttcatgagca tagctaggtg aaacggttga aacacggttc gcatagagaa
     5701 tacctgcctt catccagttc agacagttgt tccatcgaag ggtgccatca gcgtaacgtt
     5761 caaggccaac tccaaacaaa tcacccaaca ttccttctga aaattgtcct tggaattcta
     5821 aattatgaat ggttaaaact gtttcaatgt cctcataggc ttgaatccaa cggtattttt
     5881 ccttcaacaa gaaaggaatc atagctgtat ggtagtcatg aacatggaga agatcaggaa
     5941 taaagtcaat cctttccata gcctcaatgg cagccagttg gaaaaaggca aagcgttctc
     6001 cgtcatcaaa atcaccgtaa acatgaccac ggaagaaata atattgattg tcaataaagt
     6061 agaaggttac accatttaat actgttttct taattccaca atactgtctg cgccaaccaa
     6121 cgctcacctc aaaatgaagc acatcttcaa tctgatttcc aaatttagcc tctaccatat
     6181 catagtaggg taaaatcact gcaacttcgt gcccagcttt taccagtgat tttggaagag
     6241 cgccaatgac gtctcccaaa ccacctgttt ttgaaaaggg tgcaccctct gctgctacaa
     6301 ataaaatttt catgaatgaa tatcctctgt tactttagca cctttcttaa ccacaactgg
     6361 atgttctgca gttcctcgaa tcacaacacc aggctcaact tcaacccctt tgtccaagat
     6421 agcatattcg acctgagccc cttctccaat aacaacacga gggaagagca ggctatcttt
     6481 aaccaagcta tccttatgga catgaatatt acgtgataga acagaattag ctacttgacc
     6541 ttcaataata ctaccagagg caaactgaga agtgcttacc ttagatgtat tagcatagta
     6601 agttggctct tcgtttttga cctttgtata aatcttttgg tttggtgaga aaagagaata
     6661 gaatttttgt gattcaagca tatcgatatt cgcttgataa taagatttaa cagagtgaat
     6721 attggctaga tagcccgtgt actcgtaggc gaaagctccc tcttttacag ccaaatcccg
     6781 taaaacatag cgcaatttct ctggatgttc ttttttagct tcttcttcca agtgttcaat
     6841 caaccaaggt gtatcaacga caaagatatc tgtagacata ttgaacgttt cagctgttga
     6901 cttgctatca aagagtttat gagaaagaac atggtctgtt tcatctacat ccaagattgc
     6961 atttacttct gaaatatctt tcttagctag ttttttataa actacagtga taggctcttt
     7021 tgttgtacta tgtaggtgga aaacttggtt caaatcaatg ttaataagaa catcgcagtt
     7081 gagggcaacc gtttggtttg agccagaacg tttcaaataa gtaagaagct gttggtagta
     7141 ttcttttcca actgtactac tttctacacg ggtattgtaa attcctagat agtaatggct
     7201 aagaagggtt gataagcccc actcgcgtcc tgaacgaata tggtcaaata ctgagctgat
     7261 attatcctgc tggaaaatac caaagacact acgaacacct gcattagcaa ggcttgaaag
     7321 tgggaagtca atcaaacgat atttcccacc aaatgacaaa cttgctactg gacggtggtc
     7381 cgtcaatgtc gacatattgt gaaaaccaac tgtatttcct aaaatggcag aatatttatc
     7441 aatcttcatc tgttgctacc cccactactt cattatatcc tacaacttgt acttcatctg
     7501 ttccatcaat ttcgacaccg tcagaaataa tcgcaccttc accaataatg gcacgtttaa
     7561 tcttagctcc ttgaccaatg atagctccac tcatgataac tgaatcaagg acttccgctc
     7621 cttcgcgaac ttgcgcgcct gttgaaagga tagaatgttt aacagttcca tcaacgaaac
     7681 atccgtctac aactaatgag tcttccacat gagcatttgc cccgaggaag tttggtggtg
     7741 aaatcaagtt tcttgagtaa atcttccatt gacggttacg actatccaag gcattttctg
     7801 gagaaatata ctccatgttc gcttcccaaa gtgactcaat agtaccaaca tctttccaat
     7861 aaccactaaa ttcgtaagca taaacacttt cacctgactc aaggtaattt ggaatgacat
     7921 ttttaccaaa gtctgacatg ccaaccttgc tcttttcagc agcgactaac atattacgaa
     7981 ggcgttgcca atcaaaaatg tagattccca tagaagcttt tgtagattta ggttgagctg
     8041 gtttttcttc aaattcaaca atacgattgt tagcatctgt gttcatgata ccaaaacggc
     8101 ttgcttcttt aagagggacg tctaaaactg ctactgtcaa gctggcatta ttatccttat
     8161 gagactggag catatcatca tagtccattt tgtagatgtg gtccccagac aaaatcaaga
     8221 catactcagg attgacactg tcgatatagt cgatattttg gtaaatagcg tgactagttc
     8281 cctcaaacca acgatttcct tcacttgcag aataaggttg aagaatagag acacctgaat
     8341 taataccgtc tagtccccag cttgaaccat tcccaatatg gttgttgaga gcaagtggtt
     8401 gatactgtgt aacgacccca acattatgaa tccctgagtt ggcacagttt gatagggcaa
     8461 agtcaatgat acggtagcgc ccaccaaatt gcacagctgg ttttgcgatg ctttgagtga
     8521 gtttaccgag acgagttcct tgcccaccag caagaatcaa agctaacatt tcatttttca
     8581 ttttctactc cttttgggtt tttatttgtg acggttttag tagatttcaa gcgacgtttg
     8641 attttccata cacttgctcc catagccggt agggtaaagg ttaaggtctg ctcataatct
     8701 ttccatagtc cttcttgcgt ttgaacagtt tgattatgtt ctttccaaac gcctccccac
     8761 tcttccaact cagtattcca tacttcttcg taaattcctg caacgggtag tccgattgta
     8821 aaatttttcc gctcaacagg taccatgtta aagatacaga ctaacatttc tcccttttta
     8881 cccttacgaa taaaggaaag aacactctgg tctcgattat ccgcatcaat gatttcaata
     8941 ccatcatagc tggtatcgat ttcccacaga cagcgatgat ctttgtaaaa ctggtttagc
     9001 tgagaagtga aatacttcat cttagcattc attgggtctt ctaggttaga ccattccaac
     9061 tgttcttcag atttccattc taggaattga ccgtattcgc tacccatgaa gagcaatttc
     9121 ttaccagggt gacaaatttg gtacgtatag agattgcgca agcctgcgaa ttgattgtaa
     9181 cgatctcccc acatcttatg catcatactc ttcttgccat gaaccacttc atcgtgcgag
     9241 aatggcaaga gataattctc cttgaaaaca tacataaagc tgaaagtcac caggttaaag
     9301 tcatatttac gataaatcgg atcttcttcg tagaaacgga ggatatcatt catccagccc
     9361 atgttccatt tgtagtcaaa tcctagacca ccaatctctt tcattcccgt aatcttggtt
     9421 gcagacgaac tttcttctgc aatcatcatc acatctggat attctaactt aataacttca
     9481 ttcaagcgtt gaaggaaata ataaccttca tagttgagat ttccgccatc tttattaggt
     9541 gtccatggag catcatcata gtccaaatag agcatgttgc taacagcatc cacacgaata
     9601 ccatccaaat gatagacatc aatccaatgc ttaatgcaag aaattaagaa ggactggact
     9661 tcattttttc caaggtcaaa attaagggca ccccaaccat ggttatgagc cttattatgg
     9721 tcttggtatt caaaagtcgg tgtcccatca taataagcta aggcatcatc gttgatggta
     9781 aagtgacctg gtacccagtc cacaataacc ccaatattat gggtatgaca ctcctcgaca
     9841 aaatcttgaa actcctctgg tcggccataa gcatgctcta aagcgaagta acccataagc
     9901 tgataccccc aactcaagcc caaaggatgg gacatcaagg gcataaactc aatatgagta
     9961 tagttcattt caacgagata aggaatgagt tcatccttga gctgggcaaa actataagga
    10021 ctgccatcag aatttctttt ccatgatcca gcgtgaactt cataaatatt gacaggacgc
    10081 tcttcaaagc cccaacgttt tcttcgtgcc agccaaagtc catccttcca tttcttctca
    10141 ggaagctctg ttaagattgc ccctgttcct ggacgagcct catatctgac agcaaaaggg
    10201 tcaatcttca tcagttgatg accattttga cgtgtgacat gatatttgta aatatgccct
    10261 tcttgagcca tattggtaaa gacttcccag accccaaaat catttcttac cattggaatc
    10321 tgattttcaa tccagttggt aaaatcacca accaagtgaa cagcctgagc attaggtgcc
    10381 caaacacgga aggtatagcc atgctctcca tttagttctt ccctatgtgc tcctagataa
    10441 tgttggagat aaaaattttc acccgtcata aaggttttta atgcttctct attatccata
    10501 tactcccctt ctcctgtaag cgttttctat gcttttatta tactaccttt ttagagaaga
    10561 ttcaagtaaa ttactatact tctttaatta ttttgaaaat ctacaacaag ttcacttact
    10621 cgttcaattg taaatcaata ttttttcaaa aaattgcgaa aacgcctttc tttttctact
    10681 atagtgaaat gaaataaaac atgcgcaaat cgattaagga atttaa
//
LOCUS       DAVLIK010000060        10628 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLIK010000060 DAVLIK010000000
VERSION     DAVLIK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10628
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.060"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(131..1555)
                     /locus_tag="VXE87_001818"
     CDS             complement(131..1555)
                     /locus_tag="VXE87_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0843317.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2100..4379)
                     /gene="pulA"
                     /locus_tag="VXE87_001819"
     CDS             complement(2100..4379)
                     /gene="pulA"
                     /locus_tag="VXE87_001819"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0843318.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4491..6449)
                     /gene="ligA"
                     /locus_tag="VXE87_001820"
     CDS             complement(4491..6449)
                     /gene="ligA"
                     /locus_tag="VXE87_001820"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0843319.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRSLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6542..7720)
                     /locus_tag="VXE87_001821"
     CDS             complement(6542..7720)
                     /locus_tag="VXE87_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0843320.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVCLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFFPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSLSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7800..8663)
                     /locus_tag="VXE87_001822"
     CDS             complement(7800..8663)
                     /locus_tag="VXE87_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0843321.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8666..10567)
                     /locus_tag="VXE87_001823"
     CDS             complement(8666..10567)
                     /locus_tag="VXE87_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0843322.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVEEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3180 a         2347 c         1913 g         3188 t
ORIGIN      
        1 tttagaagta gagctgtact attctagttt caatatacta tagtaccaaa aagttcgtat
       61 tttttctata attattatta ttttatagca aaaaaataaa accaggaaaa caatttcctg
      121 gttttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc gcttcaatgc
      181 tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat gggaaattat
      241 ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt ttttcagcaa
      301 tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg aattcagatt
      361 cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt aaaacaggac
      421 caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa agcactggcc
      481 agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt tcttgtgcat
      541 cctcaatcaa gccccaaatg aagtcggctg aagcattatc aataacaggt gtaatatcag
      601 cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc aaagtagcta
      661 atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa cgttgtcctg
      721 agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct gcatcttcta
      781 gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata ccagctaaac
      841 gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg acttctttgt
      901 gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg aaaacacctg
      961 ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg gaaccttgtg
     1021 ttggtggctt aaacatgacc acattccctg caatcaaggc aggtgcaatt ttagaagcag
     1081 ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact ggttcacgac
     1141 ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc attgcttgtc
     1201 cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta cgcactactt
     1261 ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta ccaatttctt
     1321 ccttatcgcg ttctaaaata gctgctgttt tatgtaaata agccgcacgt tcaactgctg
     1381 ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca tcagcttcag
     1441 tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa taaatcgtaa
     1501 tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt gtcaaattct
     1561 tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaatc acaacccttt
     1621 ttgcaaaatt tttgagatta ttttcacaaa cttgattttt caaagtatac tcaataaaaa
     1681 taaaaaaaat ccactacgtc aaggcgaggc taatgtggtt tgaagaaatt ttcgaagagc
     1741 gtgaatgagt atcatctata gtaaaataaa aaaactgaac aatttggttg gggacagcca
     1801 aaccaatttc tcacaatgtt tcagaaacaa gggtgtgcta ctccaatttc agcctactat
     1861 aactgtcata gattgctgaa acaaagtcta ggtaaaagtc ttcataataa aaagacctcc
     1921 tatcaagtgt tcaaaaactt tgataggagg tcttgttttg tgaaaatatt tatcaaattt
     1981 tctatacaag tgagctgtta gccaggttct ttctattctt tcaatttcaa tgaatggatt
     2041 ttttactaat actcataact gggaatttgt ctgtgtaaaa atagcgagat agatggtatt
     2101 tataaaacac tcaagacagc tagactaata tcatttaaaa cattatcttc ttttgagcga
     2161 ctgttggtta ccaacatagc taaatttcct gcattttcaa attgataggg ttctgattta
     2221 gcattcacaa ccaccaagag gtgttctttg ccgtgaactt catagataag gtagccgcta
     2281 tgttcaatcg cagaatgcac aaagacatga tggtaaattt catcatagct agagtaagaa
     2341 aaggcaccag tttttgtctt caatcggatg acttgacgga taaactcaat actgtcttga
     2401 cgctcattaa tcaagttcca gttcacttgg ttcacactgt caggagcatt atagctattc
     2461 atcgcacgct ctctatcatc atgggtcaac tcaccatttt caccagtcgc aaccagtttg
     2521 gtacgaccaa attcttgacc gatttccata aaggccatcc cctgcatgag cagattcatg
     2581 gctgtggcag tttcgacctt gcgcatgatt tgctctgaac tttggtctgg atgaagggtt
     2641 gccaataaat cgtgaagatt gtaattgtca tgggcttcta catagttaag cacctgattt
     2701 ggatgtgtat agcttcctaa ttcacgactt cctaggattg ctttagctag aattggctct
     2761 gtcgcagcac cactgacaaa acctgacttg atagcaccat aaacttctcc ccctttgaca
     2821 gcatcgcgct gattgtcatt aaagaaacca atatttggca tctggtaggc attgtccttc
     2881 ttggccttat cataaggggc aagacctgtt cccatatccc atccttctcc atagaggata
     2941 atgttggagt cgatttcatc caagctttga cgaatcatct gcatggtctt gacatcatga
     3001 atccccatca agtcaaaacg gaagccgtca atattatatt cctgcaccca gtatagaaga
     3061 gaatcaatca tatacttgcg aaacatttcg tgttcactgg ctgtttcatt tccaacaccc
     3121 gttccattct ggaaggtacc atctggattc atacgataat agtaatcagg gactgttgtt
     3181 tggaatggtg catcaacaac tgagaaggta tggttataga ctacatccat aatgactcca
     3241 atacccgcat cgtgataagc ttgaaccatc accttcaaat cacgaatgac ctgagctgga
     3301 tcatctggat tagttgaaaa actagtttct ggcgcgttat agttttgtgg atcataaccc
     3361 cagttgtagg ttacatttcc atcctcatcg tattctttat gacggtctgc aattggttgc
     3421 aattgaacat aattgtagcc cagcttcttg atgtaatcaa aagcagttga ctggccgtat
     3481 tggttaactg ttccagcctg agcagcaccc aagaaagttc ctcgaagatg ttcatctaca
     3541 cccgatgtag gtgatttagt caaatcacga atatgcattt cacagataac tgccttacat
     3601 ggattttcca agcgccaagt agcctccgaa ccgtgcttaa cctcgaagtt ttcaacttgc
     3661 ttttctacat ggctcagaat agctgaacgt ttgccatcag ggctggtcgc gattgtataa
     3721 ggatcacgtg tcagtgtttg gtgatgaggg aattggactt gatactgata agccttacct
     3781 accaaatctt cctcaacatc caaactccag acaccgattg tattgtcctt atgattataa
     3841 gagtagctat tgcctctttt catctcaaaa gtcttccaaa cgggtgcatc attagcagct
     3901 gattcataaa cgacaacttg cacttctgtc gctgtaggtg accagaggga aaaatgagcc
     3961 tgattgtcct ctacacggca acccaattct ccttggtaac cccaatgatg gtcaaaacta
     4021 gcactgttaa tggccttatc aaaggcaaaa ggattttgat ttttatagaa aggactggca
     4081 atagcaggat tttcagagta ataaatccta tcatcgcctt ccaaaatcca gacctctgtt
     4141 aataggggat agtgattaaa acggatagaa tattctttac tagtttgacc tgtatgaacc
     4201 acaaaattca agctttctat aacatgtgaa cttgggtgtt caaagctaaa taaagctcca
     4261 aaataatctt ctttgtaggt tagcaaatca attcgttgat cctgactttt tacaaaggag
     4321 caagtgtcat attctccatt cttacgatgg taatgaatgc gcatagggta gttatacatt
     4381 ttttattttt cctttttact ttgtttctat ttcactaata aatttttgtc aatctcgtct
     4441 caattaacag acatagtcat attctctaaa ctctgttttt aaacgatcca ttacaaactt
     4501 tctagccatg cctcatctct gacctggata ccaagttctt gtgctttttg cagtttactt
     4561 ccagcgtctg cacctaccac gacgaggtcg gtctttttag aaacactacc tgtcactttg
     4621 gcacccagac tttcgagttt acttttagct tctgagcgct tgagtcgttc caattttcct
     4681 gtcaatacca cggtcaaacc tgacaaggcc gcatccgcta ctaccgtctg tcctttatag
     4741 tccagattga ccccagtttc tttcaattct ctgagcagaa tttcagagcc ttctgtcgca
     4801 aaataagtct gaagactttt ggcaatcacg ccacctagac tttcaatact agccacttcc
     4861 tctgaatctg cctgagacag attttcaatt gaatggaaat attgaagtaa aagctgacta
     4921 gccttgcttc cgacatgacg aattcccaaa ccaaataaga gcttctcggc agaattttcc
     4981 tttgatgctt ggatagcctg atacagttta gcagcggact tttccttaac cccctctaaa
     5041 aggaggaaat cctcttcttg caaacgataa atatccgcca catccttgac taaattagca
     5101 gcaaaaagct tctcaacaat agatggacca aggcctgtaa tattcatagc atcacgagaa
     5161 gcaaagtgaa tcaagccttc catgatttga gcagggcaac gcggattgat acaacgtagg
     5221 gccacttcat cttcaaagtg caacaagtca gagttacaac ttggacagtt tgtagggata
     5281 tctagttttt cttcagaaac ccgtttggac tctaccacac gtaaaacggc agggatgatg
     5341 tcaccagcct tatatacaat gaccgtatcg tcttttcgga tatctttttc agcaatataa
     5401 tctacattgt gcagggtcgc acggctaaca gtcgtaccgg caagttgtac tggtgttaga
     5461 ttagcagttg gagttacaac accggtacgg ccaactgtcc agtcaactga taagagttga
     5521 gcttcttttt cttcggcagg gaacttgtag gctactgccc actttggagc cttaactgta
     5581 aaaccaagtt cttcttgact tgctaggtcg ttgaccttga ttaccactcc atcaatatcg
     5641 taaggcagat tttcccgttc ctgtcctact tcttggataa aattccagat ttcatctatg
     5701 ttttcagcca agattcgctt aggattgacc acaaaaccta gttgttctag gtacttcaaa
     5761 cccttttctt ggctatcacg agttgaaggg ctggcttctt gatagagaaa cgttgcaaga
     5821 ctacgcttgg caactactgc tgtatccaac tgacgcagag ttcctgctgc cgcattacga
     5881 ggattagcaa attcaggctc tccattttct tggcgcactt ggttaacttg gtcaaaggaa
     5941 gcgcgtggca tgtaacattc cccacgaact gtgatatcta gttcttctgg caaagtcaaa
     6001 gggatgtcct taacacgctt gaggttttct gtgatatttt caccaattga accatctcca
     6061 cgtgttaccc cagcaaccaa aatccccttt tcataagtca gcgagataga taagccatcg
     6121 attttcagct cacaaatata ggtcggatga gccacttcct tacgaacacg cgcatcaaaa
     6181 gcatctagct cctcacgtga aaaagcatcc tgcaaactat aaagaggata ctgatgactg
     6241 tatttttcaa aaccatctaa aaccttgcca ccaacacgat gagtcggact gtctgctagc
     6301 acttgctctg gataagcagt ttctaactcg accaactcac ggtaaaggcg gtcatactca
     6361 ctgtctgaaa ccgagggatt atcgctggta tagtactcag tcgcatagcg attgagcaaa
     6421 gcgactaact cattcattct tttattcata agaccatttt accataaaac aagccctcct
     6481 cacaaacgag aagggcggaa aaaacactta gtttgaaatt atttttgaaa ctcaagcaac
     6541 cttatatcaa tttttcaaaa tgagttcgaa cataaataaa cgatatacaa gacaagatga
     6601 taacaccact tccaattatc aggaaagaag agagatgtac acttggcaag actgtcataa
     6661 atccttttgc aataggcata aatagaatag ctaaggtaaa aattgtactc agtactctcc
     6721 caagaaattc gctctcaacc ttggtttgta cttgagtaaa aaagtgaata ttaaaaatcg
     6781 tcataaacaa ttcacaaact aaatttccag aaagggaaag aaaagttgga agtggtaatc
     6841 ccatcataaa aactccgaca cctgtcaaag ccagtaaaat caaaagatta taaatattag
     6901 ctttaatttt actagctaga agagccccaa tgatggaacc aatagccccc atagttaaaa
     6961 tacttgcata ggctccttct gacccgtaaa gctgattcga aaagggaagt agaaattcaa
     7021 aagctgcaaa aaagaaatta acgctggaag ctaccagcaa aaggaagaaa atttcttgct
     7081 gatgccagat atagtgtaac ccatccttga tatctacaaa aatatctctc ccagtaaaag
     7141 cctttttctc ttgaactttt gcttcctctt ttggaaagaa agccactaga acaaaagcaa
     7201 tgaaaaaagt cagcgagtct agcagtagcg tcatatggag acttgcaaac tgtaaaacaa
     7261 ggaaggaaag aacaggagag ctaacaccta caacctgcaa aaccagctct aggcgagaat
     7321 tatagatcac aatctcatct ttctccacca cttcagttat gatagcttta ttggctgtgc
     7381 gagaaaaggc aaaagcaata gcctgcacaa tgttagcaac aatcaaagcg ccaatcatcc
     7441 agctatcatt ccttatgaaa gaaatagcca gacaaagaat cccacaaaca agatctgccg
     7501 tcattaaaat cttacgacga gaaaaacggt ctgaaataac tccgccaaag ggattgacga
     7561 gaatagatgt gacgagctca gaaatctgat acattcctaa aactgtctgt cctatagtcc
     7621 ccatagaagc caagcagaca ctatttccat aatcatagag catatttccc attttattga
     7681 tagccccacg gctaatcaac tgcactgcat agcgattcat attaaagctc ctctcaaatt
     7741 ttgaaactat tgtatcaaaa ccgaaaggag ctttttattt tttcccttat ttgggaaaat
     7801 taacttttga caaatttttc gtagtgttcc tgataatagg ctacttgctc tggaagacct
     7861 aacacatcaa aaatatgtat ggcctcttgc atctgcttac agccttcttt acactgtcct
     7921 ttttgatata aggcaaaacc ttttaaataa tggaaaacat tacgctcata aagcttaata
     7981 cctttgtcaa taatcttctc tgtataagcc tcaaaatagt tggcattata aaaagaagaa
     8041 tgctctaaac aatgctggta acaattgagg gccaaaatca acactaatct cttatggcga
     8101 ctaatctctt ggtaaaattc ctccctctcc ataacttctc taccaatccg agtgacatag
     8161 tctacatcgt agaaactata gaggttaccg aaaagaatca actcatacat ggtccattct
     8221 tctgttttga agagataatc tgctacctta tccaaatcat cctgcttcat atcataactc
     8281 gcatctcttt gacaaatcag accttgtagc aaaatccagt tcagctcaaa ataaagggaa
     8341 gtcgtcgaac tcttagactt ttcaagttgt tctctttgaa gcttttgaaa acctgcaata
     8401 tcgtttgaat agtaaagtgg gataatctgt gccatcatag acacatgttc atgattatga
     8461 aaattccttg ccttatccat gaaattttcg attgttacat gaatgttatc caaaatctca
     8521 aagaaacggg agactgccag gtcagactcc ccaagctcaa agcgagataa ctgagaggta
     8581 gagcaggatt cgcctgctgc ttcctttaaa gaataatttc cacttgttcg aaattcacga
     8641 aatacttttc caagatgttc catctttaca cctgatctga taattcttcc cactcaagca
     8701 tagcttcttc ctgacgatgg ctgattttgt ccagctcagc ctgtaattcc atgagtttgt
     8761 cggcatcgtt tgtttccaac atttgttcag aaatggcttg gctttgactt tctagctctt
     8821 caatttcagc ttctagactt tcgatttgtc gcatgagttt gcgaacttct ttttgacttt
     8881 ctttctgggc ctgatagtca ttgactggac ttgcttcctt tgcttgattg ctagttgaag
     8941 cttcctcagt ctgactcatt tctgctgttg ctttcttctc aacatagtag tcgtaatctc
     9001 caaggtagag agttgaacca ttctcagaca attccaaaac atgagttgcc acacgattga
     9061 taaagtaacg atcatgactg acaaaaagca aggtaccatc aaagtcaatc aaggcatttt
     9121 ctagcacttc cttactatca atatccaagt ggttggtcgg ctcatccaga atcaaaaagt
     9181 tattgttttc catagacaat ttagctaaaa gcaaacgagc tttttcgcca ccagatagca
     9241 tgccgactga ttttttaaca tcatctcctg agaaaaggaa ggctccaaga cggttgcgga
     9301 tttcaacttc tggtgtcagt ttgaaatcat tccagagttc atccagcacc gtattacttg
     9361 gtgtcagctt gctttgggtt tggtcatagt aaccaacctc aacattagcg ccaaagcgct
     9421 tttctccctt gataaacgga atttgatcca cgattgattt gataaaggtt gattttccga
     9481 taccattggg accaacgata gcaacagcat tcatcttacg aaggtctagg ttaatcggtt
     9541 gtgacaggac ttccccatca tagccaacag ccgcattttc aacagtcaaa acaacattgc
     9601 ccgacgtttt ttcagactgg aaggtcatgt tggctgcttt cttgccagct tccggcttgt
     9661 ccaaacgctc cattttttct agttgtttac ggcgagattg agcacgtttg gtcgttgaag
     9721 cacgaactag attgcgattg acaaagtctt ccagagcagc gatttccttc tgttgctttt
     9781 catagttttt tgcctcagta gctagctttt gctccttcaa ctcgacaaaa cgagagtaat
     9841 tccccacata gcgatccaag gaatgcttgg tcaaatctag cgtaattgtc gcaaccttgt
     9901 ccaagaaata acggtcgtgg ctgacgataa tgagggcacc gctatagttt accaagtaat
     9961 tctctagcca ggagatggtt tcaatatcca agtggttagt tggctcgtcc aagaccaaga
    10021 gattgggctt ttcaaggagc attttagcta gagccaaacg agtattttga ccacctgaaa
    10081 gttcagctat tttcatctgc cacatagact cgtcaaactt gaatccattc aaaatcgctc
    10141 gaatatcagc ttcataggta aagccgcctg cttggcgaaa attctcagat aagtggtcgt
    10201 aatctgacat cagtttatcc aattcatcgc cagacttttc acccatctcc aactccatct
    10261 gacgaagttg tttatctgtc cgacgtaagt catcaaagac atgaagcatt tcatcgtaga
    10321 tggtattttc agactcaaaa cggctatctt gggctaggta agacagagaa atatcttttt
    10381 tcttattgat ttctccgcta gttggctcct cttcttcaac taaaatcttc aaaagagtag
    10441 acttacctgc accatttttc ccaacaagag caatccgatc tcgttcatca acctgcaggt
    10501 tgatattatc gaaaagaacc tctcctgcaa aagaacgttc aattttatta gcttgtaaaa
    10561 taatcataag agtagtatag catgtttccc taaggcattc aagataatcg taagtctttt
    10621 agtacaac
//
LOCUS       DAVLIK010000061        10451 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLIK010000061 DAVLIK010000000
VERSION     DAVLIK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.061"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..191
                     /locus_tag="VXE87_001824"
     CDS             <1..191
                     /locus_tag="VXE87_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0843323.1"
                     /translation="GKEYENRTVSFAISSKGEKMKVENISYRVDHRKLFDNISFDTSS
                     SDVTLITGKNGTGKSTLL"
     gene            complement(557..1867)
                     /locus_tag="VXE87_001825"
     CDS             complement(557..1867)
                     /locus_tag="VXE87_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0843324.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2104..2976
                     /locus_tag="VXE87_001826"
     CDS             2104..2976
                     /locus_tag="VXE87_001826"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0843325.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3107..3953
                     /locus_tag="VXE87_001827"
                     /pseudo
     CDS             3107..3953
                     /locus_tag="VXE87_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            4156..5041
                     /locus_tag="VXE87_001828"
                     /pseudo
     CDS             4156..5041
                     /locus_tag="VXE87_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857688.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            5218..6225
                     /gene="gap"
                     /locus_tag="VXE87_001829"
     CDS             5218..6225
                     /gene="gap"
                     /locus_tag="VXE87_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0843326.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHNVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6293..7129)
                     /locus_tag="VXE87_001830"
     CDS             complement(6293..7129)
                     /locus_tag="VXE87_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0843327.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            7255..9450
                     /locus_tag="VXE87_001831"
     CDS             7255..9450
                     /locus_tag="VXE87_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0843328.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETKAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEASWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            9503..9655
                     /gene="rpmG"
                     /locus_tag="VXE87_001832"
     CDS             9503..9655
                     /gene="rpmG"
                     /locus_tag="VXE87_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0843329.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNLKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            9665..9841
                     /gene="secE"
                     /locus_tag="VXE87_001833"
     CDS             9665..9841
                     /gene="secE"
                     /locus_tag="VXE87_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0843330.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            9896..10432
                     /gene="nusG"
                     /locus_tag="VXE87_001834"
     CDS             9896..10432
                     /gene="nusG"
                     /locus_tag="VXE87_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0843331.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         3263 a         1817 c         2277 g         3094 t
ORIGIN      
        1 aggggaaaga gtatgaaaac agaactgttt cttttgctat tagttcaaaa ggagaaaaaa
       61 tgaaagtaga aaatatttcg tatagggtgg atcatcgtaa attgtttgat aatatttctt
      121 ttgatacttc gagttcagac gtgacattaa ttactggtaa aaatggtaca ggaaagtcaa
      181 ctttactata gtagattgaa actagaatag tacacatcta cttctaaaat attgttagaa
      241 atcgatttga ctatcctgat ctatttgtcc tgttcttatt tcatttcact atatctcaaa
      301 ttgagtatga cgaagtgcgc tcccatgtcc tgggaacgca ctttcttcat atttttcata
      361 ttcttgaatc catcgataaa gactattggg atgaattttt aaagttgaac taatcatttt
      421 tacaggatga gatttacagc agagagtttg aaggctttat caaaggtttt tcttggcata
      481 atgacttttc ctcgtttcca cttaattttg tgtctacttt attataccaa gtccaccctt
      541 aagttagata ataaatctaa cttaaggaag ctagaaggat gagaatccag gtggtcaaga
      601 gtcccaaact taagctgatg gggacaccca gaataatttg ctttttgaag gcaaggccac
      661 gttcctctat attgggaagt gagagttgaa tgagagaacc agctgatgaa aagggtgaga
      721 tattagtaga tagagcgcca ataacggtgg ctgttgtgag taagtgaata tcaatctgag
      781 gattttgagc actgatgata gcaatgatgg gaaagagggc tggagctaca acggataggg
      841 tggaactaaa gagtgacatc actccggcta tcacacaaaa gaacagaggt aaccagaaat
      901 gaggaatggt tgttgtcatg aggtgcccta tcagtgtgac taaacctgac ttgaccgcta
      961 gagacattag taagctcatg ccgcagagca tgataattgt agcccaggga accttagcta
     1021 aaatggcttc ttgcttccct aatttgagcc ttaaggcgag gcagaccatg agtattgaga
     1081 caaagccaat atcaaatgtt ttttgataag tagctatcca ggcgatgttt gggaaaatga
     1141 gatgcaacaa gggaaaaagc caaaccaaaa ccatgctgct gatcatgagc aaggtggttt
     1201 gtctttgaac cttgctgagg agtggtggtt ggtcaatagt caaggatgag tttgttcttc
     1261 ccttactata gtgactgtaa caggataata aaagcaagac gatgagtggg tagataatgc
     1321 tgacgataaa gatatgattg ccaagtgaaa aagcttgctc ttcccatccc atttgcttaa
     1381 acaggccttg aaagacaatg cctgagctac tggttatcaa attagcccct cctgaagctc
     1441 cccaattgac ggcttgagct ccaatcaaag ggtgtttgtc cgctttttga cagagggtaa
     1501 tcgctagagg acagcaaacg gccatagtag tgaaaaatcc agcacctaaa gcagacaaaa
     1561 gggttgccat caggtataaa atcatgtaga gggcgttagg gtgggtgcgt gtgcggtaga
     1621 gaatgtgttg agccaaaaca tcaagagtac cgttagttgt tgcaacgtta taaaagagag
     1681 agacgctaaa aatggtaaaa aagagtgagg ttggccaaaa atgaagaagt tctttggggc
     1741 ttaatcccat gagagtggtt gcgatgaggt aagaaaaagc aatagccagc aggccaatat
     1801 tgattttggt gcggtaacca attccaatgg ctagagcaat ggcgctaatc attattaaat
     1861 gaatcattga attgtccttt cagttagaat atggaaatag gttggcaatt ttggcgctca
     1921 aaagaccacc tgtttcctat tggtacttga ctattataca caaaaaaaat acaattgtct
     1981 tgacaattgt attgacactt gttagaatta aaaatgaggt attcaggctt gtgatttcct
     2041 atggaagtta atagtgattg cctctaatgc ttacaagtga tattaaaaat agaggaccta
     2101 gtgatgtcaa tcatttcaac tgatttaacc ccttttcaaa tagatgatac attgaaagca
     2161 gccttgcgag aagatgttca ttccgaagat tacagtacca atgccatttt tgatcatcat
     2221 ggccaagcca aggtgtcgct ttttgccaag gaagctggtg ttttagcggg gctaaccgtt
     2281 tttcaaaggg tttttaccct atttgatgcc gaggtgacct tccagaatcc tcatcaattt
     2341 aaggatgggg atcgtttgac tagtggcgat ttggttttag aaatcatagg ctcggtgaga
     2401 agtctcttaa catgtgaacg cgttgccttg aattttttac aacatttatc agggattgct
     2461 tcgatgacag ctgcttatgt agaagcctta ggcgatgatt gcattaaggt atttgatact
     2521 cgaaaaacta ctcctaattt acgtcttttt gagaaatatg ccgtgagagt tggcggtggc
     2581 tataatcatc gctttaattt atcagatgct atcctgctaa aagacaatca cattgcggca
     2641 gtaggtagtg ttcaaaaggc aattgctcaa gcgcgtgcct atgccccttt tgtgaaaatg
     2701 gtcgaggtgg aagtggaaag ccttgctgct gccgaagaag ctgcggcggc gggtgctgat
     2761 attatcatgt tggataatat gtcattggaa cagattgaac aggccattac cctaattgca
     2821 ggacgttctc ggattgaatg ttctggaaat attgatatga ccactattag ccgttttcgt
     2881 ggtttagcga ttgattacgt ctccagtggt agtttaaccc atagtgctaa gagtcttgat
     2941 ttttccatga aggggttaac ctaccttgat gtctaagttg taaaataaac taacttttta
     3001 aaggatgtct ttcctctaga acgagtttta tgtcagatag tttaaacgcc tcttcaaata
     3061 tagtaaaatg aaccaaaaat agtacacaat gtggtataat cttcttatgg catattcaat
     3121 agattttcgt aaaaaagttc tctcttattg tgagcgaaca ggtagtataa cagaagcatc
     3181 acacgttttc caaatctcac gtaataccat ttatggctgg ttaaagctaa aagagaaaac
     3241 aggagagcta aaccaccaag taaaaggaac aaaaccaaga aaagttgata gagatagact
     3301 taaaaactat cttactgaca atccagatgc ttatttgact gaaatagctt ctgactttgg
     3361 ctgtcatcca actaccatcc actatacgct caaagctatg ggctacactc gaaaaaaaag
     3421 aaccacacct actatgaaca agacccagaa aaagtagcct tatttcttaa gaatttaata
     3481 gtttaaagca cctagcacct gtttatattg atgaaacagg attcgatact tatttttatc
     3541 gagaatatgg tcgctcatta aaaggtcagt taagaagagg caaagtatct ggaagaagat
     3601 atcagaggat ttctttggtt gcaggtctaa caaatggtga gttaatcgct ccaatgactt
     3661 acgaagagat gatgacgagc gacttttttg aagcatggtt tcagaagttt ctcttaccaa
     3721 cattaaccac accatcggtt attattatgg ataatgcaag attccataga atgggtaagt
     3781 tagaactctt gtgtgaagag tttgggcata aacttttacc tcttcctccc tactcacctg
     3841 agtacaatcc tattgagaaa acatgggctc atatcaaaaa gcacctcaaa aaggtattac
     3901 caagttgcaa taccttttat gaggctcttt tgtcttgttc ttgtttcaat tgactatata
     3961 tcacggatac agttgggaaa gaagctatta aatatttgga gagtcctttt gggatgaaca
     4021 tgtcaaatat tactatagat gggcaagaaa agatgggcaa gaaatggatc tgagtcaaac
     4081 gatgcttctt atgctcaagt agtgagtctt tatgaggata caagtatctc tgttagtaat
     4141 aatgagacgg acaaagtgtt ggctggatcc ctctatactg atacaaatga acagggatta
     4201 acgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa tttgacagct
     4261 aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc cgaagctagt
     4321 aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga tgacatggag
     4381 gacagcaaca gtttcatgct gtcttatcaa atggaaacga ttttgaaaga ggctggattt
     4441 acgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac aaaagtagta
     4501 acagaagagt tacagaaaaa taagaagtat actgtgcttt ctcaacagag agttcttgat
     4561 attgtgatta cctttattcg tgttattcag ggattattga ttgtgctttc atcacaagct
     4621 attgtggtag cagcggttat gattggtatc attatttaca tcaatatcat gcagcgttcc
     4681 aaggaaatag gtgtcatgaa ggcagttggt tatcagaatc gtgatgtcaa aggaattttt
     4741 atttacgagg ctatctggat tgtaggcatc gccttgctgc tggcattttt ggttgcacaa
     4801 ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat cactaaagtt
     4861 tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt acttggttat
     4921 gtctcagcct acttctactt ggttatgtct cagcctactt ctacttggtt atgtctcagc
     4981 ctacttcccg gcgcgtaaga ttagtaaaat ggatcctgta gaatcgttac gctatgaata
     5041 ataagggatt ccttgattta cagtcttaaa aagaaactca cacagaaaaa caatggccat
     5101 acttgcaatt caactcaaat agttgtataa taggtttgtt gaaaggtgat ttgtagtgat
     5161 tcaagttact cttttcacaa taaaaatttc atgattttca taaggaggaa atcactaatg
     5221 gtagttaaag ttggtattaa cggtttcgga cgtatcggtc gtcttgcttt ccgtcgtatc
     5281 caaaacgtag aaggtgttga agttacacgc atcaacgacc ttacagatcc agttatgctt
     5341 gcacacttgt tgaaatacga cacaactcaa ggtcgtttcg acggtactgt tgaagttaaa
     5401 gaaggtggat ttgaagttaa cggtaaattc atcaaagttt ctgctgaacg tgatccagaa
     5461 caaatcgact gggctactga cggtgtagaa atcgttcttg aagctactgg tttctttgct
     5521 aagaaagaag cagctgaaaa acaccttaaa ggtggagcta aaaaagttgt tatcactgct
     5581 cctggtggaa acgacgttaa aacagttgta ttcaacacta accacaacgt tcttgacggt
     5641 actgaaacag ttatctcagg tgcttcatgt actacaaact gcttggctcc aatggctaaa
     5701 gctcttcaag acaactttgg tgttgttgaa ggattgatga ctactatcca cgcttacact
     5761 ggtgaccaaa tgatccttga cggaccacac cgtggtggtg accttcgccg tgctcgcgct
     5821 ggtgctgcaa acatcgttcc taactcaact ggtgctgcaa aagctatcgg tcttgtaatt
     5881 ccagaattga atggtaaact tgacggatct gcacaacgcg ttccaactcc aactggatca
     5941 gttactgaat tggtagcagt tcttgaaaag aacgttactg ttgatgaagt gaacgcagct
     6001 atgaaagcag cttcaaacga atcatacggt tacacagaag atccaatcgt atcttcagat
     6061 atcgtaggta tgtcttacgg ttcattgttt gacgcaactc aaactaaagt tcttgacgtt
     6121 gacggtaaac aattggttaa agttgtatca tggtacgaca acgaaatgtc atacactgca
     6181 caacttgttc gtactcttga atacttcgca aagattgcta aataattctt gagttgatag
     6241 aaagcaaggc tttgtggtct tgctttttta tatggaaaaa tggatgacac gatcatccat
     6301 tcttttttaa ttctttttca aatgtatttg aaagggtagt gaaagttagc ttctctaaag
     6361 taagtgggtg ggtaaaggaa agtcggaagg catgaagcat aagccggctt gtctttgatt
     6421 tactattata gagagggtct cccaggatag gaagattatg atgcgaaagg tgcacacgaa
     6481 tctgatgggt tcgccctgtc tttagcttgc aatgagccaa ggaagtcttg tttgagaatt
     6541 gctttaatct gcttacatgc gtttcagcat attgcccatt ttttgcatca actattcttt
     6601 ttctacgatc atggcgatca cgtccaattt tgtctctgaa aacaagttct tttctgttga
     6661 tatttccatc aactagagcc caatattctc tagaaatctc ttttttctcc aataagcgat
     6721 tgagaatggg caggataaaa ggatttttgg caaagagaac taagccactg gtttccatgt
     6781 ccagacgatg aacgacatag caggtttggc caacataggt actgacatgg ttaagaaggg
     6841 caatttcgtt tggttgatta ccatgcgttt tcatcccctc tggtttgttt acaataatca
     6901 agtgttgatc ttgataaact tcctgcacta agtctgggtt gccccaaggg atcgtctttt
     6961 gggaataatc ttcctcgtca aaagtcaact ggcaaacatc tccaggattt acgatttcct
     7021 tccagtggac ttcttcttga tttatcaaaa tatgtttctt gattctcaaa aaatgacgga
     7081 tttttctagg gatgaggagt tgttcctcaa gtaattgctt tactgtcatt tgaggtagag
     7141 aggcgggtaa tgtaaatgtg aattgcatac agatattgta acaaaaaaag ccctatttgg
     7201 ataggaaata gctaaattct tgtcttccta tgatgaagat gataaaataa acgcatgaaa
     7261 ttagataaat tatttgagaa atttctttct ctttttaaaa aagaaacaag tgaactagag
     7321 gactctgatt ctactatctt acgtcgctct cgtagtgatc gaaaaaaatt agcccaagta
     7381 ggtccgattc gaaaattctg gcgtcgttat catctaacaa agattatcct tatactaggt
     7441 ttgagtgcag gcttgctagt tggaatctat ttgtttgctg tagccaagtc gaccaatgtc
     7501 aatgatttgc aaaatgcctt gaaaactcgg actcttattt ttgaccgtga agaaaaagag
     7561 gctggtgcct tgtctggtca aaagggaacc tatgttgagc tgactgacat cagtaaaaac
     7621 ttgcagaatg ctgttattgc gacagaagac cgttctttct ataaaaatga cgggattaac
     7681 tatggccgtt ttttcttggc tattgtcact gctggacgtt caggtggtgg ctctaccatt
     7741 acccaacagc tggctaaaaa cgcctattta tcgcaggatc aaactgttga gagaaaagcg
     7801 aaagaatttt tccttgcctt agaattaagc aaaaaatata gtaaggagca aattctaacc
     7861 atgtacctta acaacgctta ttttggaaat ggtgtgtggg gtgtagaaga tgcgagtaag
     7921 aaatactttg gagtttctgc atcagaagtg agtctggatc aagctgcgac tctggcaggg
     7981 atgctcaagg ggccggaact gtataatccc ttgaattccg tagaagattc tactaatcgg
     8041 cgcgatactg tcttgcagaa tatggttgca gcaggatata ttgataaaaa ccaagaaacc
     8101 aaagctgctg aagttgatat gacttcgcaa ttgcacgata agtatgaagg aaaaatctca
     8161 gattaccgtt acccctctta ttttgatgcg gtggttaatg aagctgtttc caagtataat
     8221 ctaacagagg aagagattgt caataatggc taccgcattt acacagagct ggaccaaaac
     8281 taccaagcaa atatgcagat tgtttatgaa aacacatcgc tatttccgag ggcagaggat
     8341 ggaacgtttg ctcaatcagg aagtgtagcc ctcgaaccga aaacaggggg agttcgtgga
     8401 gttgtcggtc aagttgctga caatgataaa actggattcc ggaatttcaa ctatgcaacc
     8461 caatcaaagc gtagtcctgg ttctacaatt aagcctttag ttgtttatac gccagcagtt
     8521 gaagcaagct gggctttgaa taagcagttg gataaccata ccatgcagta tgacagctat
     8581 aaggttgata actatgcagg gatcaaaacg agtcgagaag ttcctatgta tcaagccttg
     8641 gcagaatcgc ttaatctacc tgctgttgcc actgttaatg atttgggtgt cgacaaggct
     8701 tttgaggcag gcgaaaaatt cggactcaac atggaaaagg tcgaccgtgt tcttggtgtc
     8761 gccttgggaa gcggtgttga aaccaaccct cttcaaatgg ctcaagcata cgccgccttt
     8821 gcaaatgaag gtttaatgcc tgaagctcat tttattagta gaattgaaaa tgctagtgga
     8881 caagttattg cgagtcataa aaattcacaa aaacgggtga ttgataagtc tgtagctgac
     8941 aagatgacca gtatgatgtt ggggactttc accaacggta ccggtattag ttcatcgcct
     9001 gcagactatg tcatggcagg gaaaactgga acaactgaag cagttttcaa tccggagtac
     9061 acaagtgacc agtgggtaat tggttatact ccggatgtag tgattagcca ctggcttggc
     9121 tttccgacca ctgatgaaaa ccactatcta gctggctcta cttcaaacgg tgcagctcat
     9181 gtctttagaa acattgccaa taccatttta ccttatacgc caggaagtac ctttacggtt
     9241 gaaaatgctt ataagcaaaa tggaattgca ccagccaata caaaaagaca agtacaaacc
     9301 aatgataata gccagacaga tgataatttg tctgatattc gagggcgtgc gcaaagtcta
     9361 gtagatgagg ctagccgggc tatctcagat gcgaagatta aggaaaaggc tcaaacaata
     9421 tgggattcga tagtcaatct atttcgctaa gatgcttgtc aaagcctagc tttcttgtta
     9481 taatggataa gatggaggcg ttatggcact aaaaaaagca agcctagctt gtgcggtttg
     9541 tggttcgaga aactattcaa tcaagatcag cggaaacctc aagcctacac gactagaagt
     9601 aaataaattt tgtaagcatt gtggcaagta cactacacac agagaaacga gataggagag
     9661 agcgatgcgt tttattggag atatttttag acttcttaaa gacacaacat ggccaactcg
     9721 caaggaaagc tggagagatt ttcgttctat catggaatac acagctttct ttgtagtaat
     9781 tatttacatt tttgaccagt tgattgtttc aggtttgatt cgatttatta acatttttta
     9841 gaagattagt ggagttaatt acactagaaa tcttctattt atgaaaggaa atatcatgga
     9901 tagttttgat aaagggtggt ttgttttaca aacttattct ggttatgaaa ataaggtgaa
     9961 agaaaatcta ttacaacgtg cacaaaccta caatatgttg gataatattc tacgcgttga
    10021 aattccaaca caaacagtgc aagttgaaaa aaatggaaag agaaaagaag tagaagaaaa
    10081 tcgctttcca ggttatgttc ttgtagaaat ggtcatgaca gatgaagctt ggtttgttgt
    10141 tcgaaacaca ccaaatgtta caggatttgt cggatcacac gggaacagat caaaaccaac
    10201 tccattattg gaacaagaaa ttcgcgacat tttggtatct atgggacaaa ctgttcaaga
    10261 atttgatttc gatgttgaga ttggtcaaac tgtacgtatt attgatggtg cttttgcaga
    10321 ctacactggt aagattacag aaattgataa taacaaagtg aaaatgatta tctctatgtt
    10381 tggtaatgac acagttgcag aagtaaatct aaaccaaatc gcagaattat aaccctgaga
    10441 gaggctggag c
//
LOCUS       DAVLIK010000062        10256 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLIK010000062 DAVLIK010000000
VERSION     DAVLIK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.062"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            117..3218
                     /locus_tag="VXE87_001835"
     CDS             117..3218
                     /locus_tag="VXE87_001835"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0843332.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGQSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3300..4307
                     /gene="pfkA"
                     /locus_tag="VXE87_001836"
     CDS             3300..4307
                     /gene="pfkA"
                     /locus_tag="VXE87_001836"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0843333.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4366..5871
                     /gene="pyk"
                     /locus_tag="VXE87_001837"
     CDS             4366..5871
                     /gene="pyk"
                     /locus_tag="VXE87_001837"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0843334.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6146..6394)
                     /locus_tag="VXE87_001838"
     CDS             complement(6146..6394)
                     /locus_tag="VXE87_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0843335.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDK"
     gene            complement(6561..6786)
                     /locus_tag="VXE87_001839"
                     /pseudo
     CDS             complement(6561..6786)
                     /locus_tag="VXE87_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7634..8506
                     /locus_tag="VXE87_001840"
     CDS             7634..8506
                     /locus_tag="VXE87_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0843336.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHVTSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8652..8996)
                     /locus_tag="VXE87_001841"
                     /pseudo
     CDS             complement(8652..8996)
                     /locus_tag="VXE87_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9139..9450
                     /locus_tag="VXE87_001842"
     CDS             9139..9450
                     /locus_tag="VXE87_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843337.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9454..10170
                     /locus_tag="VXE87_001843"
     CDS             9454..10170
                     /locus_tag="VXE87_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0843338.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
BASE COUNT         3199 a         1775 c         2170 g         3112 t
ORIGIN      
        1 caaaaataca aatgaataga aaataaatta gtaagctgat gaaatttttc tcaagagaag
       61 ccatttatag gtgaaaatgg tataatatag tgagaaggat agaggagaag tgtaaattga
      121 tcgcacaact agatacaaaa acagtctata gttttatgga aagcgtcatt tcgatcgaaa
      181 agtatgtgag agcagctaaa gaatacggct acactcattt ggctatgatg gatattgaca
      241 atctttatgg cgctttcgac tttctagaga ttacaaaaaa atacggcatt catcctttgc
      301 tagggcttga aatgacagtg tttgtagatg atcagggagt gaatttgcgc tttttagctc
      361 tatctagtgt gggctatcag cagttgatga agctttcgac agccaagatg cagggggaga
      421 aaacttggtc agtcctgtcc cagtacctgg aggatatcgc ggtcattgtg ccttattttg
      481 atagagttga gtcgttagaa ctaggctgtg attactatat aggggtttat ccagaaacac
      541 tagcaagcga atttcatcat cctatcttac ctctttatcg ggtcaacgct tttgaaagca
      601 gggatagaga agttcttcaa gttttaacag cgattaaaga aaatctaccg ctcagagaag
      661 ttcccttgcg ttcgagacaa gatgtcttta tatcagcaag ttctttagag aaactattcc
      721 aagagcgttt tccgcaagct ttggacaatt tagaaaagct tatttcaggc atttcttacg
      781 acttggatac tagtctgaaa ctgcctcgtt ttaatccagc tagaccagca gtagaggagt
      841 tgagagagcg tgctgaactg gggcttgttc agaaggggtt gactagtaaa gaatatcaag
      901 atagactaga ccaagaattg tctgttattc atgatatggg ctttgatgat tatttcttgg
      961 ttgtttggga tttgttgcgt tttggacaat cgaatggcta ttatatggga atgggaaggg
     1021 gttctgcagt aggcagtttg gtttcttatg ccttagacat cacggggatt gacccagtag
     1081 agaaaaatct gatttttgaa cgctttctta atcgtgaacg ctataccatg cctgatattg
     1141 atattgatat cccagatatt tatcgtccag attttatcag atatgttggt aataaatatg
     1201 gtagtaaaca tgcggcacaa atcgttactt tttcaacctt tggagccaag caagctcttc
     1261 gagatgtctt gaaacgcttt ggtgtgccag agtatgaatt atctgcaatt actaagaaaa
     1321 tcagttttcg tgacaatctt aagtcggcct atgagggcaa tctccagttt cgtcagcaaa
     1381 tcaatagtaa gttagaatac caaaaagctt ttgagattgc ttgcaagata gagggctatc
     1441 caaggcaaac ctctgtccat gcggctggtg ttgtaattag tgaccaagat ttaaccaact
     1501 acattcctct aaagtatggt gatgaaattc cactgactca gtatgatgct catggagttg
     1561 aggctagcgg acttttgaag atggactttc tgggactacg aaatttgacc tttgtccaga
     1621 agatgcaaga gttgcttgct gaaacagaag gtattcatct gaaaattgaa gaaatcgatt
     1681 tagaagacaa agaaacgtta gctttatttg cctctggtaa tacaaaaggt atctttcaat
     1741 ttgagcaacc aggtgccatt cgtctgctta agcgtgtgca accagtctgt tttgaagatg
     1801 tcgtcgcgac tacttctcta aatcgaccgg gtgctagtga ctatatcaat aattttgtgg
     1861 caagaaagca tgggcaggaa gaagtgactg ttctggatcc agtactggag gatattttgg
     1921 ctccaaccta cggcataatg ctctatcagg agcaggttat gcaggttgcc cagcgacttg
     1981 ccggatttag tcttgggaaa gccgatattt tgcgtcgggc tatggggaaa aaggatgcct
     2041 ctgccatgca tgagatgagg gcttccttta ttcaaggttc attagaagct ggtcatactg
     2101 tggaaaaagc agagcaggtc tttgatgtta tggagaagtt tgcaggttat ggttttaaca
     2161 ggtcacacgc ctatgcctac tcagccttgg ccttccagtt ggcttatttc aaaacgcatt
     2221 atccagccat tttttatcag gtcatgttaa attcttccaa cagtgattac ttaatagatg
     2281 cacttgaagc aggttttgaa gtagcctctc tatccatcaa caccattccc tatcacgata
     2341 aaattgccaa caaggccatc tatctaggtt tgaaatccat taaaggagtc agtaatgatt
     2401 tagctctctg gattattgaa aatagacctt attctaacat tgaagatttt atagctaaat
     2461 tacctgagaa ttatctgaaa cttcctctgc tagaaccttt ggtaaaagtt ggtcttttcg
     2521 attcatttga aaaaaatcgt caaaaagtat ttaataactt agctaatcta tttgaatttg
     2581 tgaaagagtt gggaagtttg tttggagatg ctatttatag ttggcaggaa tcggaagatt
     2641 ggacggaaca agaaaaattt tatatggaac aagagctttt agggataggt gtcagcaaac
     2701 atccactaca agctattgca agtaaggcta tttacccgat taccccaatc ggaaatttgt
     2761 cagaaaatag ctatgctatt atcttggttg aagttcagaa aataaaagtg attcgtacca
     2821 aaaagggtga aaatatggcc ttcttacagg cagatgatag taagaaaaaa ttggatgtca
     2881 ctctcttttc agacttatat cgtcaggttg gacaggaaat aaaagaggga gccttctact
     2941 atgtaaaagg aaaaatacaa tcacgtgatg gccgtctgca aatgattgca caagaaataa
     3001 gagaagcagt tgctgaacgc ttttggatac aggtgaaaaa tcatgaatcg gatcaagaaa
     3061 tttcacgcat tttagaacaa tttaaaggcc caatcccagt catcatccgg tatgaagagg
     3121 aacagaaaac catcgtttct ccccatcatt ttgtagctaa atccaatgaa ttagaggaga
     3181 aattgaatga aatcgttatg aaaacgattt atcgctaaaa atacggaaaa tagaagaatt
     3241 ttcaacgtaa atgtggtata atcagtaaga atgttaaaag aaaaaggagc ataaccaata
     3301 tgaaacgtat tgctgttttg actagtggtg gagacgcccc tggtatgaac gctgccatcc
     3361 gtgcagttgt tcgtcaagca atttcagaag gaatggaagt ttttggtatc tatgacggat
     3421 atgctggtat ggttgccggt gaaattcatc ccctagatgc agcttcagta ggggacatca
     3481 tttctcgtgg tggtactttc cttcactcag ctcgttaccc agagttcgct caacttgaag
     3541 ggcaacttaa agggattgag caattgaaaa aacacggaat tgaaggtgta gttgttatcg
     3601 gtggtgacgg atcttaccac ggcgctatgc gtttgactga acatggcttc ccagctattg
     3661 gtcttccagg tacaatcgat aacgatatcg ttggtactga ctttacaatc ggttttgaca
     3721 cagcggttac tactgccatg gacgctatcg ataagattcg tgatacatca tcaagtcacc
     3781 gtcgtacttt tgtaatcgaa gttatgggac gtaacgctgg tgatatcgct ctttgggctg
     3841 gtattgcaac tggtgctgat gaaatcatca tccctgaagc aggcttcaag atggaagata
     3901 tcgtagcaag catcaaagct ggttatgaat gtggtaaaaa acacaatatc atcgtcttag
     3961 ctgaaggtgt gatgtcagcg gctgaatttg gtcaaaaact taaagaagct ggagatacaa
     4021 gcgaccttcg tgtaacagaa cttggacata ttcaacgtgg tggttctcca actgcgcgtg
     4081 accgtgtttt ggcgtcacgt atgggtgcac atgctgttaa acttcttaaa gaaggtatcg
     4141 gtggtgttgc ggttggtatt cgtaacgaaa aaatggttga aaatccaatt cttggtactg
     4201 cagaagaagg ggcattgttt agccttactg cagaaggtaa gattgtggtt aacaacccac
     4261 acaaagccga tattgagcta tctagcttga ataagagctt gtcataattt acaatttagt
     4321 taataagacc aaaaaggtca tatatataaa ggagtcacaa aaatcatgaa caaacgtgta
     4381 aaaatcgttg caactttggg tcctgcggta gaaatccgtg gtggtaaaaa attcggtgag
     4441 gacggatact ggggtgaaaa acttgatgtt gaagcttcag ctaaaaacat tgctaaattg
     4501 attgaagctg gtgctaacac attccgattc aacttctcac acggcgacca ccaagaacaa
     4561 ggtgagcgta tggcaactgt taaacttgcg gaaaaaattg caggtaaaaa agttggtttc
     4621 cttcttgata caaaaggacc tgaaatccgt acagaattgt tcgaaggtga agctaaagaa
     4681 tattcataca aaactggtga aaaaattcgt gttgcaacta aacaaggaat caaatcaact
     4741 cgtgaagtga ttgcgttgaa cgttgctggt gctcttgata tctatgatga tgttgaagtt
     4801 ggtcgtcaag ttttggttga cgatggtaaa cttggtcttc gtgtggttgc taaagatgat
     4861 gcaactcgtg aatttgaagt tgaagttgaa aacgatggta tcatcgctaa acaaaaaggt
     4921 gtgaacatcc ctaacactaa aattcctttc ccagctcttg ctgaacgcga taacgacgat
     4981 atccgtttcg gtcttgaaca aggtatcaac ttcatcgcaa tttcattcgt acgtactgca
     5041 aaagatgtga acgaagttcg tgcaatctgt gaagaaactg gaaacggaca tgttcaattg
     5101 ttcgctaaaa tcgaaaacca acaaggtatc gataacttag acgaaatcat cgaagcagct
     5161 gatggtatta tgattgctcg tggtgatatg ggtatcgaag taccgttcga aatggttcca
     5221 gtttatcaaa aaatgattat caagaaagtc aatgctgcag gtaaagttgt tatcactgca
     5281 acaaacatgc ttgaaacaat gactgaaaaa ccacgtgcaa ctcgttcaga agtatcagac
     5341 gtattcaacg ctgttatcga cggaactgac gctacaatgc tgtcaggcga gtctgcaaac
     5401 ggtaaatacc cactcgagtc agtaactaca atggctacaa tcgacaagaa cgctcaagct
     5461 cttcttaatg aatacggacg tcttgattca gattcatttg agcgtaactc taagacagaa
     5521 gtaatggctt ctgctgttaa agatgctact agctcaatgg atatcaaatt ggttgtaact
     5581 cttactaaga caggtcatac tgcacgtttg atttctaaat accgtccaaa tgctgacatc
     5641 ttagcattga catttgacga attgacagaa cgtggcttga tgttgaactg gggtgttatc
     5701 ccaatgttga cagatgctcc atcttcaact gacgatatgt tcgaaatcgc tgaacgtaaa
     5761 gcggtagaag caggtctcgt tgagtcaggc gatgatatcg ttatcgttgc tggtgtgcca
     5821 gtaggagaag ctgttcgcac aaacacaatg cgtatccgca cagtacgtta agaaaaatat
     5881 aaaaacctat catatccagc tttctagcct gtatgatggg ctcttttttt gtccaggggg
     5941 caaaaagggg gcaaaacttt cataatggat tgatactctt cgaaaatcaa attcaaacca
     6001 cgtcagcgtc gccttaccgt actcaagtac agcttgcggc tagcttccta gtttgctctt
     6061 tgattttcat tgagtatgaa ataagatatg cacaaattga ttagaaagtc aaatgaattt
     6121 ctacaaatgt tttagcaatc gcaatctact tgtctagatt cgatctgata tattttcgat
     6181 ttaatgatat ggtatttaaa acctccaaag tagcttgctc cattctttta cttacgtgag
     6241 tgtagatgtt atttactgtt ttagcgtttt tgtgttccac tctaaccatt atagcattct
     6301 tctcagctag tgtactaagg agtgtgtgcc tgaaaatatg ggaactaagg ggctggttta
     6361 tcggtttctc tagtttagta tttgcctttt gcaaagtgat cttaaatgcc tttctctaaa
     6421 tttacatatc actattgttt aacaaaatct aatctacttt aggtcactta ttcttttttt
     6481 gaaatgtaga atgaactttt tcaaagtttt tcgaatcttt taaaatctgt ttgttttata
     6541 tcgccattct cccccctttt ttaattctcc ctatatagcc tgacaacttt cccgatggta
     6601 cgaatatggt tgctttcgtc taggtggatg tcggggtatt cgggattgag tttttttgag
     6661 gtagccttgg cggagtttct tgacatagtt agcgccgtct acttggaaga tgccgatggt
     6721 attatagtca atctgtgggg tattcttgat aaataggtag tcgctgtttc ttatctttgg
     6781 ctccatggac ttgctgacga cataagcgat tgggtcgtag tcgtctggga taatggaaac
     6841 tccataacta aatcgtcgtc ctgcatcgag cggctacctg cagagataaa ctacctaaca
     6901 cgagagtaag tagtctgtct gtagtcgtcc agtctgatga tttttacgat acttcgtttt
     6961 tctgatcata cagttgcctc tcggcatagg tcagaacttt accttgtctg ggtggtgccc
     7021 gttggtcgta gatagattgg atatcgctag gagaatcctt ttgaactgga ggaaagaggg
     7081 catcaatcaa gctactgaat actttaacta agtcaaatat agtatttttc ttagtagacc
     7141 taaccctttt ttcataattt ctaatggtgt ttttacttat acctatctta gtacccaatt
     7201 cttattgagt ccaaccatta ctagtctata ttgttttata gttgatttag tttggaatag
     7261 tacgctgtag ctgctaaaac atttctagga attaatttgc ctttcctaat agagttgttc
     7321 atatcttatt tcaatctact atatttttca cctctaacaa tcgcaatctc ttctttatcc
     7381 atgaataaaa acgatttcta tttttgtaag taaagcatca cacgaaatcc acgaaaatga
     7441 aaacctttgt tgtgttttcg taaaaaattt gttgacagag cacgaaacgc ctactataat
     7501 taaatcaagt ttaaggaaat aacaaaaaaa caaatcggag ggaaagacga tgaacacatt
     7561 aaatgagaaa gtaatcaata tctgtaaagc agtagttaaa gaaactttaa tccaagacat
     7621 ttaggagaaa gaaatgaaga aatcaagaaa attagccaca ttaggaatct gttcagcttt
     7681 gtttttaggc ttggctgctt gtcaacaaca acatgttact tctgagggga cgaatcaaag
     7741 gcaaagcagt tcagcgaaag ttccatggaa agcttcatac accaacctaa acaaccaggt
     7801 aagtacagaa gaggtcaaat ctctcttatc agctcacttg gatccaaata gtgttgatgc
     7861 attttttaat ctcgttaatg actataatac cattgtcggc tcaactggct tatcaggaga
     7921 tttcacttcc tttactcaca ccgaatacga tgttgagaaa atcagtcatc tctggaatca
     7981 aaagaagggc gatttcgttg ggaccaactg ccgtatcaat agttattgtc ttttgaaaaa
     8041 ttcagtcacc attccaaagc ttgaaaagaa tgaccaattg cttttcctag ataacgatgc
     8101 gattgataaa ggaaaggtct ttgattcaca agataaggaa gagtttgata ttctattttc
     8161 gagagttcca actgaggcaa ctacagatgt caaggttcac gctgaaaaga tggaaacatt
     8221 cttctcacaa tttcaattca atgaaaaagc tcgaatgctg tctgtagtct tgcacgacaa
     8281 tctggatggc gagtatctgt ttgtaggcca cgttggggtc ttagtacctg ctgatgacgg
     8341 tttcttattt gtagagaaat tgactttcga agagccctac caagcgatta aatttgctag
     8401 taaggaagat tgctacaagt atttgggcac caagtatgcg gattatacag gcgagggact
     8461 ggctaagcct tttatcatgg ataatgataa gtgggttaaa ctttaatagt gttatgatat
     8521 gacagtaatc ttaggatttt tatttctatt tttgatgact tggtgggtta tttcaatcgt
     8581 taatagccag aaaccacgca aaaatgaaac atttattggc tatatccaaa gatacgatat
     8641 tgatgggaat ggctatcaat cattaccgtg tcctcagaac tgagaggagt tcttgaaatc
     8701 gtaaaactac tttgaacaag agttacttca acccattggc tccgacggat taagttgctt
     8761 tcgtgaacac caaaatcagc cgcaatttct tcataagtgc ggtattctcg cacatattga
     8821 agagtggcca taagaaggtc ttctaggctt aatttaggtt ttcgtccccc ttttgtgtgt
     8881 ttaagttgat aagcagtttt taatacagct aacatctctt caaaagtggt gcgctgaaca
     8941 ccaacaagac atttaaatcg tgcatcagtt agttgcttac ttgcttcata attcatagaa
     9001 ctactatacc atattttgtt tcgcaggaag tctaatgcta aaatcttatc agtgagaaga
     9061 tttcttaaag tttattcttt gtagtttcat ctgtattagt atataattta acttagagaa
     9121 aataggagga ctaatcgaat ggaattaaaa gattttacag aaaaagaaca ggaaatgatt
     9181 aagaaaaggc ttacaatgtc taatattagt gacaaagaaa ctactgagaa gattctggcg
     9241 ctagtaccac aagacttgat taagcgaatc ccgttttttg tcagaaaaca tgctacaaca
     9301 cgtacgatta aacgcatttc aattgaacac cctgaactct acgctgtagc tcaaacaagt
     9361 ggtgagattc cagaaaaaga acgcgaagaa ttgcgtcaga ttatcacaac tatctttgaa
     9421 caaaagatga ataagcatag tattaagtag agaatgaaaa aatattttat tggcggtttg
     9481 ggaagcaatg cctatcatag caaggatttt cttcaagaac tagattcgca ggtctatttt
     9541 ctaaatccat atgaaaagca tcttcgagat gaaacagaat tgaaatcatg gtttaaaaat
     9601 gagattgtag aggaagaatc tatctgtctg ataggtcatt ctattggagg cgatttagct
     9661 cgttatttcg catcggaatt tgaagaagta aagaaactga ttcttttgga tggtggctat
     9721 ctagatttag ataagatttt acctttggat acagagttag aggaaactaa aaattatatc
     9781 aaatctcaaa ttatttcgga cttagatgtt cttacttcta aagaaaaatc tgaagcaaag
     9841 cattggtcag aaaatatgga gaaagctgta agacagtcct atcactggaa tgttgagtat
     9901 aatagatatg agttggctat aaattatgaa aatatagaag cgatactccg cctacggaga
     9961 aaaatacaag cttttaagag agaagtggga gataccttgt ttattagtcc tcgctatcct
    10021 aatgaagcta catggagaga ggaagcccta aaagaattgc cagactattt tgatactatt
    10081 tttttagaaa actttggcca tgagctttat actcaagcac ctaaagaaat cgctagtcta
    10141 atgaatgagt ggctcgctta ttttctatga gctacttgta ttgctggaaa tggtataaga
    10201 tgaaaatcta caagtcacta attttcatat aaccaaaaaa cgaacaggct cttttt
//
LOCUS       DAVLIK010000063        10087 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLIK010000063 DAVLIK010000000
VERSION     DAVLIK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10087
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.063"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            447..1808
                     /gene="trpE"
                     /locus_tag="VXE87_001844"
     CDS             447..1808
                     /gene="trpE"
                     /locus_tag="VXE87_001844"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0843339.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFYILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            1805..2371
                     /locus_tag="VXE87_001845"
     CDS             1805..2371
                     /locus_tag="VXE87_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0843340.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            2382..3386
                     /gene="trpD"
                     /locus_tag="VXE87_001846"
     CDS             2382..3386
                     /gene="trpD"
                     /locus_tag="VXE87_001846"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0843341.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            3383..4150
                     /gene="trpC"
                     /locus_tag="VXE87_001847"
     CDS             3383..4150
                     /gene="trpC"
                     /locus_tag="VXE87_001847"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0843342.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            4137..4736
                     /locus_tag="VXE87_001848"
     CDS             4137..4736
                     /locus_tag="VXE87_001848"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0843343.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEVAE
                     LAKLIPADVKKVGVFVSPSRAELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            4714..5937
                     /gene="trpB"
                     /locus_tag="VXE87_001849"
     CDS             4714..5937
                     /gene="trpB"
                     /locus_tag="VXE87_001849"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0843344.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGSPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            5930..6706
                     /locus_tag="VXE87_001850"
     CDS             5930..6706
                     /locus_tag="VXE87_001850"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0843345.1"
                     /translation="MPKTLTEKLNAIKVTGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(6678..6779)
                     /locus_tag="VXE87_001851"
                     /pseudo
     CDS             complement(6678..6779)
                     /locus_tag="VXE87_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            7008..7739
                     /locus_tag="VXE87_001852"
     CDS             7008..7739
                     /locus_tag="VXE87_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843346.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDENSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            7754..8905
                     /locus_tag="VXE87_001853"
     CDS             7754..8905
                     /locus_tag="VXE87_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0843347.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(8957..9616)
                     /locus_tag="VXE87_001854"
     CDS             complement(8957..9616)
                     /locus_tag="VXE87_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0843348.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEKSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            9686..>10087
                     /locus_tag="VXE87_001855"
     CDS             9686..>10087
                     /locus_tag="VXE87_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0843349.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQM"
BASE COUNT         3150 a         1841 c         2372 g         2724 t
ORIGIN      
        1 aaccatacct acgataaggc gacgttgacg cggtttgaag agattttcga agagtataaa
       61 ggtgtaccga gatgaacatc tcttcatcaa tgtctctggt cgtggaggca aggacctagc
      121 tgcgattgca gattactaga agctaaaaaa taatagatgg aaaaattaca gttctttctc
      181 tcacagagag cttgtggttg ctgaaaacaa gcagagaaag ctgtaaagtt gggttcatct
      241 gaaacgagag aagaaaacat cattctcaag ggagtgccct ttatcgcaca gcctgttaca
      301 ggagatatct gagacaggaa tgagagatag gagaaatcct ataattgagg tggcaccgcg
      361 aatttcgtcc tcacgcaagt tattttgcgt ggggattttt catacagtca ccacggacta
      421 gaagtagaac tgaaagggaa attacaatgg aacgaatcat tcatggagat gtcttatcac
      481 caatcttggc ttatatgcgc ttaaaggggc aacataaggt tattttagag agtattccga
      541 gagacaagga aacagctcgt ttttatatcc tagcctataa tccagttttt gagattaagt
      601 ttgaaaatgg ggttctctat caaaatggtc aagtgattga tcgggatccc ttggatttcc
      661 tttatgaagt gattcataag agtcagcacc actcagagct accttttggt ggtggagcca
      721 ttggttttgt gggttacgat atgatttcgc tttatgaaga aattggtcaa atccctgagg
      781 atacaattgg gacgccagac atgcatttct ttgtctatga gagctatatg gtctttgacc
      841 acaagaagga gaagatacat gtcatagagg atgcacttta tagtgagcgc agtcaagagg
      901 ccttggaaaa atccttgaac caagtgcttg aggaattacg cattcctgct ccaaatgaat
      961 ttgaagattt ggatctatct ccgttagact tcaaaccgca tatcgctcca cataagtttg
     1021 agggaatggt agaaacagct cgtgacttga ttcgtaacgg agatatgttc caatgtgtac
     1081 tcagccagcg tttttcagca gaagttactg gaaatccatt tgacttctac agaaatctcc
     1141 gcgtgactaa tccttctaat tacctttatt tctatgattt tggggattat caaatcatcg
     1201 gagctagtcc agaaagttta gtttctgtca aaaatggcat cgtgacaacc aatccgattg
     1261 cagggacgcg accaagaggg gctacggatg aagaagacaa gaccttggcg actgacctcc
     1321 tctctgatga gaaggaaaca gcagaacatc gaatgttggt agacttgggg cgtaacgata
     1381 ttggccgcat ctctgaaacg gccagtgtcc aagttactaa gtatatgaag gtggagctct
     1441 tccgctacgt catgcatttg accagcgtgg tcaaggggcg tttgcttcca gaactcacgg
     1501 ccatggatgc cttgaaagct acacttcctg ctggaaccgt ttctggagca ccaaagattc
     1561 gggcgatgag acgcatctat gaactggaaa cggaaaaacg gggcgtatat gcaggagcaa
     1621 tcggctactt gtctgcgacg ggtgatatgg atttggccat tgccatccga accatgattc
     1681 tcaaaaatca aagagcctat gtgcaggctg gggcagggat tgtctacgac tctatcgccc
     1741 aaaacgaata ccaagaaacc attaacaaag caaaatctat gactagaatt ggagaactaa
     1801 gaccatgatt ttattgattg acaactatga ttcttttacc tataacttgg cccaatacat
     1861 tgggaatttt gcagaagttc aggttctgag aaatgatgat tccaagctgt atgaagaagc
     1921 tgaaaaagca gatggtctgg ttttttctcc tggtcctggt tggccagttg atgctggaaa
     1981 gatggaagac atgattcgtg attttgcagg caagaagccg attcttggga tttgtttggg
     2041 ccaccaagcc attgcagaag tctttggtgg taagctaggt ttggctccaa aagtcatgca
     2101 tgggaaacag agcaatatca actttgaagc gccatctgtt ttgtatcaag gtattgagga
     2161 aggacgtgcg gtcatgcgtt atcacagtat tttgattgag gaaatgccag aagactttga
     2221 agtgacagct cgttcgactg atgaccaagc catcatgggg attcaacata aaaacctacc
     2281 gatttatggc ttccagtacc atccagagag cattggaacg ccagacggct tgtcttctat
     2341 tcggaatttt atcgagaagg ttgtaaagtg aggaaactag gatgaaagag attattgaaa
     2401 aactagcaaa atttgaaaat ttatcaggtg tggaaatgac ggatgtcatt gagcgtatcg
     2461 taactgggcg tgtaactgaa gcgcagattg cttctctcct cttagctctt aagatgaagg
     2521 gggaaacacc tgaagaacgc acagccattg cccaagtcat gagaggacat gcccagcata
     2581 ttccaactga gattcatgat gccatggaca actgtggtac aggtggggac aagtctttca
     2641 gttttaatat ttccacaact gcagcctttg tcttggctgg tggcggtatt cacatggcca
     2701 agcatggtaa ccgctcgatt tcttctaaat ctggttccgc agatgtcctc gaagccttgg
     2761 gaatcaatct tgacctcaaa ccagctgaac taggtaaggt ctttgataaa actggaatcg
     2821 tctttctctt cgctaaaaat atgcacccag ctatgaaata catcatgcca gctcgtttgg
     2881 aattgggaat tccaacgatt atgaacttga ctggtccact gattcatcca atggctttag
     2941 aaacacagct tcttggaatt agtcgtccag aactcctaga aagtacagct caggttttga
     3001 aaaatatggg tcgcaaacgt gccatcgtgg ttgctggacc agaagggttg gatgaagctg
     3061 gcttgaacgg aacaaccaag attgcacttc ttgaaaatgg cgaaatcagc ttgtcaagct
     3121 ttactccaga ggatttggga atggaaggct atgctatgga agatattcgt ggtgggaatg
     3181 ctcaggaaaa tgcagaaatt ttgcttagcg ttctgaaaaa cgaagcaagt ccattcttgg
     3241 aaacgacagt cttgaatgct ggtcttggtt tctatgctaa tggtaagatt gatagcatca
     3301 aggaaggagt tgccttggcc cgtcaagtga ttgctagagg caaggccctt gaaaaactca
     3361 gactgttaca ggagtaccaa aaatgagtca ggaattttta gcacgaatct tagagcagaa
     3421 ggtgcgtgag gtggagcaga tgaagctgga gcaaatccag cctctgcgcc agacctatcg
     3481 cttggcagag tttttgaaga atcatcagga ccgcttgcag gtaatcgctg aggtcaagaa
     3541 agctagccct agtttgggag atatcaatct cgatgtggat attgtgcaac aggcccagac
     3601 ttatgaagaa aacggagcag tgatgatttc ggtgttgaca gatgaggttt tctttaaagg
     3661 gcatttggat tatctacggg aaatttccag tcaggtagag attccgacgc tcaacaaaga
     3721 ctttatcatc gatgaaaagc aaatcatccg cgctcgcaat gcaggtgcga cagttatctt
     3781 gctcattgtg gcagccttgt ccgaagaacg cctcaaggaa ctgtatgact acgcgacaga
     3841 gcttggtctg gaagtcttag tggagactca caatctagct gaactagagg tagcccacag
     3901 acttggtgct gagattatcg gggtcaacaa ccgcaacttg actacctttg aggtcgactt
     3961 gcagaccagt gtagatttag ccccttactt tgaggaaggt cgctattaca tttctgaatc
     4021 tgccattttc acagggcagg atgcggaacg actagcccca tactttaacg gaattttggt
     4081 agggacagct cttatgcagg cagaaaatgt ggcccagaga atcaaggagt tgcagattga
     4141 caaaggttaa aatttgtgga ctatcgacca aagaagcggt ggaaacagcc gtttcagcag
     4201 gagccgacta tatcggtttt gtctttgcac ctagtaaaag acaggtaact ttagaagaag
     4261 tagctgagtt ggcaaagctt attcctgcag atgtcaaaaa ggttggtgta tttgtttcac
     4321 caagtcgggc agaactgctg gaagcgattg acaaagttgg cttggacttg gttcaagttc
     4381 acggtcaggt ggcagatgat ttatttgaga atttgccttg tgctagcatt caggctgtgc
     4441 aggtagatgg agagggtcat gtgcccaatt ctcaggcaga ctatctactc tttgatgccc
     4501 ctgtggctgg gagtggccag ccctttgatt ggggtcaact ggatacgact ggactagcac
     4561 agcccttctt tatcgcaggt ggccttaatg aagataatgt agtaaaagca attcaacact
     4621 ttactcccta tgcagtagat gtatcaagcg gagtggagac agatggacaa aaagatcatg
     4681 aaaagattag aagatttata gagagggtaa agaatggcat atcaagaacc aaataaagat
     4741 ggattttacg gaaaatttgg cggacgtttt gtcccagaaa cattgatgac agcagttttg
     4801 gagttggaga aggcctaccg tgaaagtcag gcagacccaa gtttccaaga ggaattaaac
     4861 cagcttttgc gccagtatgt gggacgtgaa actccccttt actacgcaaa aaacttgacc
     4921 cagcatatcg gcggagccaa gatttatctc aaacgggaag accttaacca tacaggagcc
     4981 cacaagatta acaatgcctt aggacaagtt tggcttgcca aacgcatggg taaaaagaaa
     5041 attatcgcag aaacgggtgc tggtcagcac ggtgtggcaa ctgcaactgc tgcggccctc
     5101 tttaacatgg aatgtaccat ctacatgggt gaggaagatg tcaaacgcca agccctcaat
     5161 gtcttccgta tggagctttt gggagctaag gtcgaggccg tgacagatgg ttcgcgcgtg
     5221 ctcaaggatg cggtcaatgc agcccttcgt tcatgggtgg ctaatatcga cgatacccac
     5281 tatatccttg gttctgcctt ggggcctcat ccatttccag aaatcgttcg tgacttccaa
     5341 agtgtcatcg gtcgagaggc taaacaacag taccgtgact tgacaggtcg agatctgcca
     5401 gatgccctag tagcctgtgt tggtggtggg tcgaatgcta tcgggctctt ccatcccttt
     5461 gtagaagatg agtcagtagc tatgtatgga actgaagcag cagggcttgg tgtggataca
     5521 gagcaccacg ctgctacctt gaccaagggt agtccgggtg ttcttcacgg ttctctcatg
     5581 gatgtgctcc aagatgccca tggtcaaatt cttgaagcct tctctatctc agcaggtttg
     5641 gactatcctg gtatcggtcc agagcattct cactaccacg atatcaaacg tgccagctat
     5701 gtccctgtga cagacgaaga agctttggaa ggatttcaac tcttgtctcg tgtggaaggg
     5761 attatcccag ccttggaatc tagccatgct atcgcttttg cggtgaaatt ggccaaagaa
     5821 cttggaccag aaaagtctat gattgtctgc ctatcaggtc gtggggacaa ggatgtggtt
     5881 caagtcaaag accgcttgga agcagatgca gcaaagaagg gagaagctca tgcctaagac
     5941 actaacagaa aaattgaatg ctataaaagt aactggaaaa ggaattttcg ttccttatat
     6001 catggctggt gaccacgaaa aaggtttgga cggtcttgct gaaacaattc actttttaga
     6061 agatttgggt gtctctgcta ttgaagtggg gattcccttt tcagaccctg ttgcagatgg
     6121 acctgttatc gaagaagctg gcttgcgcag tttagcccac gggacctcta cccaggcttt
     6181 agttgaaacc ttgaaaacca ttgaaacaga gattccactg gtcatcatga cctacttcaa
     6241 ccccctcttt cagtacggtg tggagaactt tgtcaaagat ctggctgata cagctgtgaa
     6301 gggcttgatt atcccagacc tgcctcatga acatgccaac tttgtagaac catttttggc
     6361 agatacagat atcgccttga ttcctttagt aagcttgacc acaggaattg agcgccagaa
     6421 agagttgatt gaaggggcgg agggattcgt ctatgccgtt gccatcaatg gggtgacagg
     6481 gaaatcaggc aattaccgtg cagatttgga caagcacttg gcgcaacttc atcaagtggc
     6541 cgacatccca gtcttgacag gttttggtgt atctagtcaa gccgatctgg aacgcttcaa
     6601 tgcggtgtca gatggtgtta tcgtcggttc aaaaatagta aaagctctcc accaaggaga
     6661 gccgattcag gattttatca gacaagcagt agcttaccaa aaataatcaa acaagtagca
     6721 agtaagagga aaggcacgaa aggaagtctt tcctttttct tttgcaggag aaaggtcagt
     6781 tttatagtga attgaatctg gaatattaca ctacggttcc taaaatattt tcagaaagcg
     6841 atttgaattt cccaataaat ttgttcagtt tttaattgat tttactatag aagatataat
     6901 tttctaaatt actctgacac agaactttaa gaaaaagcta attattgtag taatttcttt
     6961 aagaaaatga tataattcat taaaaagtat ttggaggagg aagaattatg ttgaatcagg
     7021 atctctttga ttcgcttgag gcacaaaaaa ttgtagatac tttgatgaaa gggcaaaaag
     7081 attatgtaga tgaacgtcta gaaaaaagag agacaatgat agtgtcgaat ggttatgcat
     7141 ggacgcgacc taatcatatt gatactgcat ttgcatcagc agatttgttt gagtataaat
     7201 tacaattagc aggacagact tggggatatt tagaatttga aacaaataca gaaaaatatg
     7261 ggaaagtatt gttaattata aagggtaaga agcgacttac gaaccaattt cctttggtac
     7321 aaaaaaataa gagtggctac ttatttgaat atgctcagat gaatacactt tatcttaatc
     7381 aacattcttc ctacaaaaat gatgaaaata gtcattcctt tccaattcag atggagttag
     7441 tttctgatga aatgattcaa gaaattgaac aagctactaa aaattcgaat atcgaaaaat
     7501 ttatgatttt aacttatgag gcggactcag aaaacaatat tatatctgta gatgttgtta
     7561 tgcctgatgc acgaactggt cagttacact tgattcaaga tttgtctgag tatattcaat
     7621 caagttcgta ccatttcgaa gaagctaaat atcaagatat tcctaatttt tcagaattat
     7681 cggaaacaga agattttgaa attattccaa gaatagaaaa acaagaaggt caaaagtagt
     7741 aaggagtatg taaatgttta atggtcgggt attgaaagaa ttacggctgt taaatggttt
     7801 aagtagagca gaattagctc agagaattaa tttaacggaa caagccattt ggcagtttga
     7861 gtccaacgaa acgaaaccta aattatcaac caaaatgcat ttggccaacc aatttcatgt
     7921 tgatttaact tattttgaac aggaagaaga gagcattcga tttgattctt ctgtaattgc
     7981 ctttagaaat gcagacctag caacacggaa aacaatagat attcaaacta tgtatttaca
     8041 taaggtagat agtttgattg attattttga aagttttgta attataccta atattataat
     8101 tcatgaccta agtaatgtag tgagtgaatc ttatcataag ggagaatcca ttgaggaatt
     8161 ggctctttat gccagggaaa aattaggtat ttcaaaagat aatcatgatt tgctttataa
     8221 attagaacgt tcaggcatct atatcgtgga acgattaatt aatggccaag ctgatgctta
     8281 tagcgcatgg tcaaaattgg gaagacctta tattgtgttg ggaacgaata aatcatctgt
     8341 acgtcgaaat tttgacttag ctcatgagct aggacatatt cttttacata aatataaaga
     8401 tatgaatgaa gatggcgatc gtttggagca agaagcaaat tattttgcat catgtttttt
     8461 attgccaaaa gaagagtttt tagtcaaatt tgaagagagg gttggcaagc gtgtcagcaa
     8521 tcctgatagt tatattttat tgaagtcgga tttgaatgtt tcgatacagg ctttagagta
     8581 tcgagctttt aagttaggat tattgactcc aaagcaacat tcttactttt atcgtcaaat
     8641 tgcgcaaaaa ggttacaaaa tgattgaacc tttggatgat caaatttttg ttaaaaaacc
     8701 aagcaaagta aagagtattc tggacgtcgt tttgagtaat catctagtca gtctagcgac
     8761 tataatgtct aaacaaagta ttcgtttaca gtttataagc gaaatatttt cagtcgaaat
     8821 gaaatttttt gatcagtatc aagaagatag aagaacagat cgatttgata acatcatccc
     8881 tttgtacaaa agaaataatt tataatttaa ctgtgaaata atttcatgaa ggacatatgg
     8941 cagaaattgg attttatcag acaagcagta gcttaccaaa aataatcaaa caagtagcaa
     9001 gtaagaggaa aggcacgaaa ggaagtcttt cctttttctt ttgcaggata aaggccagga
     9061 tacccgtcgc agaagcaaac tgaatcaaga tcagtaactc cgttacgcta aagacgagag
     9121 cacaagaagc taaaaagagg aaatctcctg cgcccatgcg gatatcgata aaatgagcca
     9181 aaattccaag agcaaggaag gagaccatga ccagattcca gccagaggaa gctattagga
     9241 ttaggtggaa agtcatccag accagtaagg gatattcctg atggtgaaag tcgtagatac
     9301 ccaaggtcaa accagcggtg attaggacga cttgccccaa ggaaagcaat tcccaagagt
     9361 aaagcagaaa gaggagtcct aagactaatt caaagagggc ataccagaca ggatagcgaa
     9421 ctttgcagta gcgacagcga aagcgattga agacctgtga gagaatcgga atcaaatcta
     9481 agggacgcaa gcgagtctga caggaatcgc agtgactggc tgaactgata atggatttct
     9541 ctggaaaacg gtcaatgacc aaaccaagaa aggaagcgag aatgctcccg acgagaaaaa
     9601 aataaaaatc aatcatactt atctattcgt aaaaaatggg agaaatagta taatggagaa
     9661 acatagataa gatggtgagg aaaagatgac aattcgtttt gaagaaaagg tgagtataga
     9721 aaacgctcaa tttgtatgcc agtggtccaa ctccctaggc aaatcctttc aagaacaatg
     9781 gatgggacca aggattcctt ttctactgac ccttcaagcc ttggaaggag tcttttcaat
     9841 ctttgatgaa caagagtttg tgggacttat ccagaaaatc aggctagaag acagcaatct
     9901 tcatatcggg agatttttta tcaaccccca gaaacaggag caagacttag gtagccaggc
     9961 tttaaggaaa tttgttagtt tggcctttga aaatgaagat atagatagta tttctctaaa
    10021 tgtcttcgag gcaaatcaaa gagctcagaa tctttaccaa aaagaaggat ttgaaatcgt
    10081 tcaaatg
//
LOCUS       DAVLIK010000064         9981 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLIK010000064 DAVLIK010000000
VERSION     DAVLIK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9981
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.064"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(124..840)
                     /locus_tag="VXE87_001856"
     CDS             complement(124..840)
                     /locus_tag="VXE87_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0843350.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            1188..2975
                     /locus_tag="VXE87_001857"
     CDS             1188..2975
                     /locus_tag="VXE87_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0843351.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            2972..3448
                     /locus_tag="VXE87_001858"
     CDS             2972..3448
                     /locus_tag="VXE87_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0843352.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            3476..4381
                     /locus_tag="VXE87_001859"
     CDS             3476..4381
                     /locus_tag="VXE87_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0843353.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            4368..5183
                     /locus_tag="VXE87_001860"
     CDS             4368..5183
                     /locus_tag="VXE87_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0843354.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            5190..5594
                     /locus_tag="VXE87_001861"
     CDS             5190..5594
                     /locus_tag="VXE87_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0843355.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            5847..7013
                     /locus_tag="VXE87_001862"
     CDS             5847..7013
                     /locus_tag="VXE87_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0843356.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            7129..8166
                     /locus_tag="VXE87_001863"
     CDS             7129..8166
                     /locus_tag="VXE87_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0843357.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            8374..9228
                     /locus_tag="VXE87_001864"
     CDS             8374..9228
                     /locus_tag="VXE87_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0843358.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            9378..9635
                     /locus_tag="VXE87_001865"
     CDS             9378..9635
                     /locus_tag="VXE87_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="HEV0843359.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDCDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(9677..>9981)
                     /locus_tag="VXE87_001866"
     CDS             complement(9677..>9981)
                     /locus_tag="VXE87_001866"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843360.1"
                     /translation="VVDGTDEVSSKHCFEVVDRTDEVSNHIYGKVKLTWFEEIFEEYK
                     SLHNKTHITKVLMNCTPKVRQKKSNFLGSIHSTPDTMRFFNFKDFLQLLLTHIKLF"
BASE COUNT         2860 a         1847 c         2226 g         3048 t
ORIGIN      
        1 tggttctatt tctataaaat attccacaaa ttatagaatc ttccaaaaat aggtaagcgc
       61 tacctttttg gtgtggtata ataagcatag aaaaagccca agcgattagc tcaggctttc
      121 ttcttagtga tcacggtcac atgagataaa tttaatcttg tagtaatcag atcgtttgta
      181 agtttcactg tattctaaaa cttggccagt tgattcgagt ttggtgattt tagtttgtag
      241 gacagtaggg aattgttcat cgactccgag gactgaagcc gcatgttctg gagttggaaa
      301 gactatttcg ttgatttctt caaagtgttc atcattcatg tgaatgtggt agtctaactt
      361 gaaacgatta tagatagaac tatagtattc aaggtttgga taatttgcgt tgatatattg
      421 ttctgggatg taggatgtat ggtagatata aacgacaccg tttgattcgc ggatacgttc
      481 aatcttgtag tagaattgat cgccgcgtag acccaatttt tccaagtaaa caagcttgtt
      541 tccgcgttca attgaaagaa cagttacctt atcatcttta gcattgaaga gttcaatatc
      601 tgaaaactct acaagcttgt gtttgcgcgc acgtgaaacg aaggttcctt ttccttgttg
      661 gcggacaata tagccatctt tggcaaggtc gtttaaggcg cgaacaactg tgatagagct
      721 gacatcgtac attgaaatga gttctgcttc agtgtaaaat ttatctccac tgctaaactg
      781 cccagagatg attttatttt ttaattcgtc ttttatgtat tgatatttgg gaattgccat
      841 atttttacct ctattttcct tctccataga aaattttacc ataaaagcga aaaaaatagt
      901 agtcttttga ataaaaaatt agaataatag tttgaaaaat taagcgatat agggattgct
      961 catattttat aaatgtattc tatacaaaat tattttaggt cctatattcc gaatttaaag
     1021 agcgtttgaa atgggtctaa aaatgtttga aactaattga atgtgtgtat aatagtaaaa
     1081 atgcagtaaa tatcccgaca atttctattg acaattcaaa cagattggtt tataattaat
     1141 ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg tagttttatg acacgatttg
     1201 agatacgaga tgatttctat ctcgatggaa aatcatttaa gattttatct ggtgccattc
     1261 attattttag ggttcctcca gaggattggt atcattcgct ctataacttg aaggctcttg
     1321 gttttaatac ggtagagact tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt
     1381 ttcattttga cggtgatctg gatttagaga aatttctcca aatagcgcag gatttgggtc
     1441 tctacgcaat tgtgcgtccg tctccattta tctgtgcgga atgggaattc ggtggcttac
     1501 cagcttggct cttgaccaag aacatgcgaa ttcgctcatc cgacccagca tatatcgagg
     1561 cagttggtcg ctactatgat cagttattgc caagactggt tcctcgtttg ttggacaatg
     1621 gtggcaatat tctcatgatg caggttgaaa atgagtatgg ttcttacgga gaagataagg
     1681 cttacctgag agcgattcga cagctaatgg aagagtgtgg cgtaacctgt cccctcttta
     1741 catcagatgg tccatggcga gctactctga aagctggaac cttaattgaa gaggacctct
     1801 ttgtaacagg aaactttggt tctaaggcac cttacaactt ttcgcagatg caggaattct
     1861 ttgatgaaca tggtaagaaa tggccactca tgtgtatgga gttctgggat ggttggttta
     1921 atcgttggaa agaaccgatt atcacacggg atcctaagga attggcagat gcagttcgag
     1981 aagttttgga acaaggctcc atcaatcttt acatgttcca cggtggtaca aactttggtt
     2041 tcatgaatgg ttgctcggct cgaggaactt tggacctgcc acaagttacg tcttatgatt
     2101 acgatgccct tctggatgaa gaaggaaatc caactgctaa atatcttgca gtcaagaaga
     2161 tgatggcaac acatttttca gagtatccgc agttggaacc actctacaaa gagagtatgg
     2221 agttggatgc tattccacta gttgaaaaag tttctttgtt tgaaacctta gatagcttgt
     2281 caagtcctgt agaaagtctc tatcctcaaa agatggagga gctgggacaa agttatggct
     2341 acctacttta tcgaacagaa acaaactggg atgcagaaga agaaagactt cgtatcattg
     2401 atggtcgaga tagggcccag ctgtatgtcg atggtcagtg ggttaaaact caatatcaga
     2461 cagagattgg ggaagatatt ttttatcaag gtaaaaagaa agggctatct aggttagata
     2521 tcttgataga aaatatgggg cgtgtcaact atgggcataa gttcttagcg gatacgcaac
     2581 gtaagggaat tcggacaggg gtctgtaagg atctgcattt cttactaaac tggaaacact
     2641 atccactccc actagacaat cctgagaaaa ttgatttttc aaaaggatgg actcaaggac
     2701 aaccagcctt ttacgcttat gactttacag tcgaagagcc aaaagatact tacctagact
     2761 tgtctgagtt tggtaagggg gttgcctttg tcaatgggca gaatctagga cgtttttgga
     2821 acgttggccc aactctctca ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc
     2881 gcatcattat ctttgaaaca gaaggtcaat ataaagaaga gattcattta actcgtaaac
     2941 ctacactaaa acatataaag ggggaaaact tatgacaatt gtaggatgcc gtattgatgg
     3001 acgtttgatc cacggacaag tagccaatct ttgggctgga aaactaaatg tttcacgcat
     3061 tatggttgta gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc
     3121 gacaccacca ggtgtgaaat tgagtatttt gccagttgag aaagctgcag ccaatattct
     3181 tgctggcaaa tacgatagcc aacgtctctt tatcgtggct cgtaaaccag accgcttcct
     3241 tggtttggta gaagcaggtg taccacttga aacccttaat gttgggaata tgtctcaaac
     3301 accagaaact cgttctatta cacgttctat caacgtagta gacaaggatg tggaagactt
     3361 ccacaaactg gcagaaaaag gtgttaaact tactgctcag atggttccaa atgatccaat
     3421 ttcagacttt ttgagcttat taaaatagga aaaaattttt taggaggtca ttgttatgat
     3481 acaatggtgg caaattttac ttctcacttt gtactcagct tatcaaatct gtgatgagtt
     3541 gacgatcgtt tcatctgcag gttcccctgt atttgctggt ttcattactg gtttaatcat
     3601 gggagatgtg actactggtt tacttatcgg tggtaacttg caactgttcg ttcttggggt
     3661 tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc
     3721 cttctctgtt tcacaaggaa ttgatgcacc gcttgcaatt actacaatcg ctgtaccagt
     3781 agcagctctc ttgacttact tcgacgttct tggtcgtatg actactacct tcttcgctca
     3841 ccgtgtggat gctgcaatcg aacgctttga ctataaaggt attgaacgca actacttgct
     3901 tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg
     3961 tggtgccttt gtacaatcag tagtagactt cgttgaagcc tacaaatggg ttgcagatgg
     4021 cttgacactc gcaggacgta tgcttccagg tcttggattt gcaatcttgc ttcgttacct
     4081 tccagttaaa cgtaaccttc actaccttgc tatgggattt ggtttgacag ctatgttgac
     4141 tgttctttac tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg taggtactct
     4201 tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat
     4261 tggtatttct atcgtaggta ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt
     4321 agctgtagca gcaccttcta caccatcaga aagtggggaa atcgaagatg acgaattcta
     4381 attacaaact tacaaaagaa gattttaatc aaatcaacaa acgtagcttg tttactttcc
     4441 aattaggttg gaactacgaa cgtatgcaag cttctggtta cctttacatg atcttgcctc
     4501 agttgcgtaa aatgtatggt gatggaactc ctgaattgaa agaaatgatg aaagttcata
     4561 ctcaattctt caatacttca ccattcttcc ataccattat cgctggtttt gaccttgcca
     4621 tggaagaaaa agatggtgta ggttcaaaag acgctgttaa cggtatcaag acaggtttga
     4681 tgggaccatt cgctcctctt ggggatacaa tctttggttc acttgtacct gctatcatgg
     4741 ggtcagtcgc agcaactatg gctatcgctg gccaaccttg ggggatcttc ctttggattg
     4801 cagttgcagt agcgtatgac atcttccgtt ggaaacagtt ggaatttgct tacaaagaag
     4861 gggttaacct tatcaacaac atgcaaagta ccttgacagc tttgattgac gctgcatctg
     4921 tacttggtgt cttcatgatg ggtgctcttg tagcaacagt gattaacttt gaaatttctt
     4981 acaagttgcc aatcggtgaa aagatgattg atttccaaga catcttgaac caaatcttcc
     5041 cacgtttgct tccagcaatc tttactgcct ttatcttctg gttgcttggt aaaaaaggta
     5101 tgaactctac taaagctatc ggtattatta tcgtacttgc tttggctctt tctgcccttg
     5161 gtcactttgc acttggaatg taattcctta tgactaaatc attaattttg gtgagccatg
     5221 gtcgcttctg tgaggagctt agaggtagca cagaaatgat tatgggccca caagacaaca
     5281 tttacacagt agctcttctt ccagaagatg gcccagaaga atttactgct aaatttgaag
     5341 ctgttattga aggattggat gatttcctag tctttgcgga tcttctcggt gggacacctt
     5401 gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat tgacctttac gcagggatga
     5461 atcttccaat ggtgattgaa tttatcaatg cgagccttac aggcgcagat gcggactaca
     5521 agagccgtgc tgcagaaagc attgtgaaag ttaatgacct gttagcgggc ttcgatgatg
     5581 acgaagatga ataatactct tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt
     5641 aggtatatgt tactgacttc gtcagtctta tccggcaacc tcaaagcggt gctttgagca
     5701 gcctgcggct agtttcctac agattttagt tggaactcga ttcaattcat gtgacaacgt
     5761 gaaaatcgtt agagcatttt atatagaata tacatgggaa tggagcttac tcccattccc
     5821 atatttaata gaaaaagagg aactcaatgc tacattatac aaaagaagac ttgctcgaat
     5881 tgggtgcaga aatcactacg cgtgaaatct accaacagcc tgatgtatgg agagaagctt
     5941 ttgaatttta tcaagcaaaa cgtgaagaaa ttgcagcctt tctacaagaa atcgctgata
     6001 aacatgacta tattaaggtt atcttgacag gtgctgggac ttctgcttat gtgggagata
     6061 ccttgctacc ttactttaag gaagtctatg acgaacgcaa atggaatttc aatgctattg
     6121 cgacaacaga tatcgttgcc aaaccagcaa cctatttgaa aaaagatgtg gcaactgtcc
     6181 ttgtgtcttt tgctcgtagt gggaactcgc ctgaaagtgt ggcgactgtt gatttggcca
     6241 aatccttggt ggatgagctt tatcaagtga cgattacttg tgcagcagat ggtaaattgg
     6301 ctcttcaagc tcacggtgat gaccgtaatc tcttgctctt gcaaccagct gtctctaatg
     6361 atgctggatt tgccatgact tctagcttta cgtctatgat gttgacagct ctcttggtct
     6421 ttgatcctac agaatttgct gttaagtctg aacgttttga agttgtatct agtcttgccc
     6481 gtaaagtttt agacaaggta gaagatgtca aagagctcgt tgatttagac tttaaccgtg
     6541 tcatctatct aggcgctggt cctttctttg gacttgctca tgaagctcag ctcaagattt
     6601 tggaattaac tgctggtcaa gttgcgacca tgtatgaaag cccagttggc ttccgtcacg
     6661 gtccaaaatc tcttatcaac gacaatacag ttgttttggt ctttggtaca acgacagcct
     6721 acactcgtaa gtacgacttg gacttggttc gtgaagttgc tggtgaccag attgctcgtc
     6781 gtgttgtgct tttgagtgat caagcttttg gtcttgaaaa tgtcaaagaa gtggtccttg
     6841 gttgtggcgg tgtcttgaat gatatttacc gtgtcttccc ttacatcgtt tatgcccaac
     6901 tctttgctct attgacttca ctcaaggtag aaaataaacc agatacaccg tctcctacag
     6961 gtacagtaaa ccgtgtagta caaggtgtca taattcacga atatcaaaag taagacagtg
     7021 tttatgaatt cttgacaaga ggatttgtaa attatcagat aaaccataga ttgtcagtac
     7081 gctttctatg gtttgtttgc ttgagagaaa tagtaaaagg agaacagaat gaaagcatac
     7141 acagagcgtg tatttggaaa tgttgagggc gaggatgtct tggcctatcg atttgagaca
     7201 gacggtggct accaacttga ggttatgact tatggcgcga ccatcttgcg ctatgtcgca
     7261 cctgacaagg ctggaaattt tgccaatgtt atcttgggat ttgatgactt tgatagttat
     7321 gtaggcaata gtcccaagca tggagcaagt gtaggtcctg tagcgggtcg tattgcaggt
     7381 gcgacctttg agctcaatgg taagacctat gaccttgagg ttaataatgc tagcaactgt
     7441 aatcacagtg gttcaactgg ttgggattcc agcttgtttg aagttgaaga agtaagcgat
     7501 catggcttga ctctctacac agagcgtaca gatgggacag gagggttccc tggaaatctc
     7561 aagatttgga tcagttatca cttggaagaa actggtgcct atgaaatcat ctacaaggta
     7621 acgaccgatc aggatacgct ggtcaatcca accaaccaca gctatttcaa cttgtctggt
     7681 gatttcacgc agacgattga ccgtcatgtc ttccaactaa acacagaggg catttactca
     7741 atcgctcctg acggtgttcc tgccaaaact ccagaagcca accgtgatgt ggtcaaacac
     7801 atctacaatg gtaccttgtt gaaggatatc tttgcagaag aagatgagca aatccagctg
     7861 gcatcaggtt tggatcaccc atttgccctt cctgcaggcc atgacaatgc tggattcctt
     7921 tatgaccaaa attcaggtcg cttcctgctt ttcaagacag aagctccttg ctttgtggtc
     7981 tacacagcaa actttgtgga tgaaagtgtc atcataggag gtcagccaat gctacagcac
     8041 aatgggattg ctcttgaagc gcaagcttta ccagatgcca ttcacagtga ccttaaaggc
     8101 caagtcattc ttaaagctgg tcaaaccttc accagtaaga cacgttatga acttgttgtg
     8161 aaataaaaaa agctggtcaa aaagtcttta aaattaaaat aacgcatatt gtcaggtgat
     8221 gaaaagtttg ataatatgcg ttttattatg aaatgattta ctttatctta tcctgaaatg
     8281 gtgttatttt tgagttatct ggcttgactt tcttgatgga aattatataa tagttgtaat
     8341 aacaataatt acaacgagaa aagaggacca tttatgacct atgaatacaa gagtcacatt
     8401 tatttggcag agacagtttt aaatgtaaag gatttggcca gtcaaacagc cttttatcag
     8461 caagttattg gtttagaaat cttatctcaa actgagacag agtccattct aggccttggt
     8521 ggaaaagtct tggtacagct gattcaagca caagagagcg gagaagtgag ggaacattat
     8581 ggtctttacc atttggccat tctcttgccc acacgcaagg ctttggctga tgtcttgaaa
     8641 cacctgacag atttgcaaat tcctcttgtc ggcggtgcag accatggtta cagtgaagct
     8701 atttacttgg aagatttgga gggaaatggc attgaactct atcgagataa gccagtttcc
     8761 acatggaata ttcgagaaga tggacgcatt atcggagtga cggaggctct tgcggcgcag
     8821 gacatttatg agttggggga aagagtagag ccctttatcc tggcagaagg tacaagaatg
     8881 gggcatattc atctttccgt caaggatagt cgaaagtcca gccagtttta tcaaaaggtg
     8941 ttagggctag agaataaatt cagtgtgcct ggcgctagtt ggattgcggc tggagattac
     9001 catcatcatt tagcagttaa cgaatgggga ggaaaaggtc tggcttcgcg taagcaaggc
     9061 ttaccaggtt tagcctacta tgtcatcgaa gtcgcacata aaaaagaact gttaacgatt
     9121 gcccaacgag cacaagaagt tgacgcacca atcaaatgga tgacatcgat ccaattggaa
     9181 atcacagact cagatggcat cgtgacccgt attcgtttag caaggtaaaa ttaggaattt
     9241 ttaataagtt ataagtattg ctagtttgct ttttgaacgg tctttggtaa cagaactgcg
     9301 tgagctggat gggtgagaat tttgacaaag aagctgatta gagatataat gaagaaaaat
     9361 cgagcaagga aaaagaaatg acaaattcaa agtatattac ttgtttgaaa cgttcagagg
     9421 gccagttgtg tgggattcaa aagatgattg aaggagattg tgactgtgct gatattgtga
     9481 cgcaactgac agcagtgaga tctagtgtag agcgcgtgat tgagatgata attaccgaaa
     9541 atcttactga atgtatcaat cagccactag atgattctga agctcaaaag gaacgcctag
     9601 aaaaggctat ccgatacttg attaaacgga aataaatgaa tgttttgaga cgatatgtgc
     9661 aaaggtctat taactattag aatagtttaa tgtgagtcaa aagaagttgt aaaaaatctt
     9721 taaaattaaa aaaacgcata gtatcaggtg ttgaatgtat tgaccccaaa aagttagatt
     9781 ttttctgtct aacttttggg gtgcagttca taagaacctt ggtaatatgc gttttattat
     9841 gtagagactt atactcttcg aaaatctctt caaaccacgt cagcttcacc ttgccgtaga
     9901 tatggttact gacttcgtca gttctatcca caacctcaaa acagtgtttt gagctgactt
     9961 cgtcagttcc atccacaacc t
//
LOCUS       DAVLIK010000065         9032 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLIK010000065 DAVLIK010000000
VERSION     DAVLIK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.065"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..188
                     /locus_tag="VXE87_001867"
     CDS             <1..188
                     /locus_tag="VXE87_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843361.1"
                     /translation="LTFLIELFTSYFNSLYFPLYSMKSKAQTRKLATGCSKHCFEVVD
                     KTDEVSSKYCFEVADGS"
     gene            complement(372..1220)
                     /gene="dprA"
                     /locus_tag="VXE87_001868"
     CDS             complement(372..1220)
                     /gene="dprA"
                     /locus_tag="VXE87_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0843362.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1316..2005)
                     /locus_tag="VXE87_001869"
     CDS             complement(1316..2005)
                     /locus_tag="VXE87_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0843363.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVCLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(2017..2895)
                     /locus_tag="VXE87_001870"
     CDS             complement(2017..2895)
                     /locus_tag="VXE87_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0843364.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2885..3754)
                     /gene="licA"
                     /locus_tag="VXE87_001871"
     CDS             complement(2885..3754)
                     /gene="licA"
                     /locus_tag="VXE87_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0843365.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            complement(3771..4793)
                     /locus_tag="VXE87_001872"
     CDS             complement(3771..4793)
                     /locus_tag="VXE87_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0843366.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4798..5505)
                     /locus_tag="VXE87_001873"
     CDS             complement(4798..5505)
                     /locus_tag="VXE87_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0843367.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIEKIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5841..7328
                     /gene="tacF"
                     /locus_tag="VXE87_001874"
     CDS             5841..7328
                     /gene="tacF"
                     /locus_tag="VXE87_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0843368.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSSISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7338..8141
                     /locus_tag="VXE87_001875"
     CDS             7338..8141
                     /locus_tag="VXE87_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0843369.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8143..8952
                     /locus_tag="VXE87_001876"
     CDS             8143..8952
                     /locus_tag="VXE87_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0843370.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2837 a         1811 c         1520 g         2864 t
ORIGIN      
        1 atttgacttt cctgatagag ttgttcacat cttatttcaa ttcactatac tttcccttat
       61 actcaatgaa aagcaaagcg caaactagga agctagccac aggttgctca aagcactgct
      121 ttgaggttgt agataagact gacgaagtca gctcaaaata ctgttttgag gttgcagatg
      181 gaagctgacg tggtttgaag agattttcga agagtattat atgagaaaaa tcctctactc
      241 tactaatcca cttagaaaaa acgcatatta tcaagtgtta aaaacttgct aatatgcgtt
      301 ttattatgga aatgttgggt tcattttctc ttaaaattga ttttttctta gaattctagc
      361 ttaggtcatt tttaaaattc aaattccgca agaacatctt gcccactggt gaccaatttt
      421 gctccttctt gaatcaaatg atggcaaccg tctgatagtc catctaaaat gctaccagga
      481 atagcaaaga catcgcgtcc ttcttccatt gctcgctcac acgtaatgag actacctgaa
      541 cgcatcttag cctctgctac aatcacacca cgacaaagtc cagcaatgat gcgattacgg
      601 gcaggaaaat gaaatttcag aggttgttcg ccaggtccat attcacttag aaccagatgg
      661 tcattgccga tgtagtcttg caagcgttta ttggctttag gataaaacac atccagtcct
      721 gttccaatca ctgcaatggt ttttccgcca ttctgaagag ctgccatatg agctgctgtg
      781 tcaatgccct tggccagacc actgacaata accagttcat tttccaagcc ttgaatgact
      841 ttttcaactg acttagctcc ctgtttgcta caagcacgac tgcccacgac cgctaccttc
      901 gggaatttca ggaggtcaag atttcccttg taaaataaaa gtacaggcgc atcatatatt
      961 tcactcaaat cccaaggata acagtcatct aaaatagaga aagatggaaa tttttgaaac
     1021 tctttcgaca aatgcgcatc gtctatctga aaataacgtt ccataaaaac ggctggatta
     1081 cggcaacctg atatatctgc aatatcaccc aacaaaagct cctgatcaac attttcaccg
     1141 tattctagca ctttcaaaat ctgttgattg gtcaaacctg atttttttaa cttatagatt
     1201 tcatagtttg tgattttcat aaataactcc atttcttttt ctactcatct atctattcgt
     1261 aaaagttcgt aaaaaatcaa aaaacatccg actattttgt cagatgttgg aatctttaat
     1321 tttcgttttt aagaatttct tctaatttac gatagtcttg gacactatcg atctcataaa
     1381 tgctattgcc ttctaattct tcaacataga catctagctc tttgatatta tccttaacca
     1441 tattgtccca atagagatca acaaattcac cacttgcata agccttgtcg ataaagctga
     1501 caatcttttc tgcagttgga gcatcccaga aggatacacc actaaggatg cgacctgcct
     1561 tgctatcaac aataatgtct tgaaccttgt agtcatctcc atagaccaag aaccattcgt
     1621 tggtacaatc ttcacgataa acactaaaat aagtcgaacg agtcaaatca ttgcggaaca
     1681 tatttttaaa gagatagtta tctgcatcaa taacatagct gttggccaat tcttctttta
     1741 caagatagag agagtaaaag ttattgtagt cagcgtattt atcattgaaa acgaggcaaa
     1801 caccgtattt ttcttttaaa taatcgaatt gttctttaag ataaccaacg atgatgatga
     1861 tgtcattgat tcctttttct ttgagaaact caatttggta ttcaatcaaa ggtttttgat
     1921 taacctgaac caaggcttta ggggtatttt cagtcatagg acgcaagcga gttcccaatc
     1981 ccgctgctaa gataatggct ttcacacgaa tctcctttat tctttaataa taatataaac
     2041 tccagcaatg acgacaagtg acgtcataat ggtcagcata tctaatgatg ttcccaagaa
     2101 aagagctgcg aacaagacag tccatactac atagctcacg ttcaagcctg tagccttggc
     2161 tggttgcaag cgattgatag cgatataata agccaaatag gaaatcatat caaaggctac
     2221 aaagacaatc atgagaccta gcaattgtcc attggctact gcaacaaatg actgatgaga
     2281 gaagagcaca atcacaagat aggacaagaa cgaagttact tgacggatta agagggcttc
     2341 gatttcactc aattcacttt ccatggcaaa agagctaaga acactctcac ttccccatgc
     2401 aatagcacaa accaaagcac aaagaatccc aatgtagaaa gaattaacct gttcaacctt
     2461 ataggtctgg gcaataatcc ctccaataat caagacaatc ccaaatacag tatttttcga
     2521 aatcttgtgc ttcaaaaaga agaaagccaa tagaactgaa atcgcagggt aaatagccga
     2581 tacagatgaa gctaaagaac ttccgatata cttaactgca taaagattgg cctgcatacc
     2641 gatagggcct gctagcaagg ctcctatgat aacactgaca ttgcgaatat ttaagaaaat
     2701 tgagaggcga actttccctt cttttaccaa gagaaaagct agtaagataa agatgctcaa
     2761 aaaatcatga gttgcagcca ccacaaaggg tgacaaatct gtaaaaatcg aaaagatata
     2821 agcactaacc gttagaccca agccccagaa aatacctgag agaaggccaa aaggaactcc
     2881 gtttttactt ttcatctgaa cctccataag aagccaaacc tttaatagct ctttggtaac
     2941 gattcacacc atagtcacca aaatcttcac cttgctcttc cttatagaca gtccatagac
     3001 tccaaatagt atcttgtaaa attttataaa tagcaatctt ttcatgagaa accggtgttt
     3061 ggtcactctc atagtgagat aagaaagttt cttcctcttg ggaagtgaat tcagactcta
     3121 aaaagagggc agccaaatcc cacattggat cattcattga tgaatattcc cagtcaatca
     3181 aataaagtcg tccttgaggt gattcgataa agttttcagg caccaaatcg atatgacaag
     3241 attttctgtc aacacctaag tcagccagtc ttttctctaa ggagaagact gcatttctaa
     3301 cagattcata gttggcataa ggaatttgtt cttcaatcaa ggattcgtat tttttgattt
     3361 cttcaaaagg agcaaattct cctcttaatt ccttagcaga cgtatgaata gtttgtaata
     3421 ttggagcaat tttgtcgaac ttggtcttga ttgacgttga atcaagcgta atcgcagatt
     3481 cgatatactc atttactttg ataccagctt caatatcaaa aagataattt tttacatcta
     3541 agcctaaatc ctttagtagt tcaagattgt acttttcatc ttgtcgattg ataagctttt
     3601 ctgtcccttt accaaagaat ttaacaatgt attgcttatt tgttgttttg gccaaatagt
     3661 tttgattggt cattccaccc agttgttcaa cactgaggac ttcctcttct tgactaagta
     3721 aggaagaaat tttttcttta atgattttct ccacaattaa cctccagtac ttatacttcc
     3781 cacttaaaca ctgttttaaa ggctgtgttt aaatcggttg caaagacacg atgaatatct
     3841 ttaatttctc ttacaggttc ttctagataa aggatatttt taagacgatt ggcaaatttc
     3901 ttgacttcca tcatttggat agcattttta aaatcaatgc gaccagaacg agatgaccca
     3961 accaaaatca agcccttttc taaggcatcg cgagtattga gattgacttt atattcgcta
     4021 actcccatca tgagaatcgt tccctgagga cgaatgtagc gaatcaagtc attaatagct
     4081 ggtccagtac catcaccacc acaacattca aaagcatggt caaaggccaa atcttcagga
     4141 atattatccg taatatagca ttctttggca aatgagaaga gttccaactt ttcccaatga
     4201 cgaccaataa ccacaatctc tgattctggc aaagtatagt tgataatatt ggcaaccaca
     4261 aaagctaaac ttccatctcc aataacggcg atccgctccc gcttgctatg agcaagagtc
     4321 aatagacgat tcatagcgtg catgcccaca ctgacaaact ctgtaatggc tgcaaccgta
     4381 tcttcaatag catcataagc caccacacga tctttaggga gagaaacaaa ctctctcata
     4441 aagccatcaa atccactaga caagaaatgg gtccctgtca tgtagttttc atagaattct
     4501 tcatcactct gcataggaga ctgattggga atcatgacaa ctttttgacc aacctcgtag
     4561 gttccggtcg ggtcagaaat gacggttcca catgactcgt gaatcattgc cattggaagc
     4621 tttttattca aaatcttggg atcacgtttt ccctgatagt aacgctgatc cgcatgacag
     4681 acagccatgt agttgggacg gataaggata tgattctctt ggtcaatagc ctcttcctga
     4741 tatttgacat tgataaactt aggcttagtt agttgataaa tttgattaat cattttacta
     4801 gtctttctca atcatacttt ttgcaatctt caaatctgtt acggttgtaa tcttcagatt
     4861 tgagtattca cctttggcca aggccacatc ttttcctttg atcacaaaga ttttacatgc
     4921 atctgtcaag atttccttct cttcatcaga aagagatcca taaaggtcca tgaagtcctt
     4981 gcaacggaat gtttgaggtg tttgtccttg ataaaggtga gcacgatttg gaatatctgt
     5041 aataaattga ccattggtac tttcaacgat agtatcaacc gcttctacta ctgtatccac
     5101 tgcgtcatga ttttgggcaa gttggatatt gtcctgaatc atgcgaagtg taataaatgg
     5161 acgaacagaa tcgtgggtaa caacgatatc ctctgaagta agcggacgat aagcatcaat
     5221 ggcttcaatg attttctcaa tacttgtatt gcggtcagca ccaccctttg taatgatgat
     5281 acgttcctta taaagaggaa gatatttatc tacaagatct tctgcatgag aaacccagtc
     5341 tccatgaaca ccaactacaa ttttttcaat acttggttcc aagacaaatt tttcaattgt
     5401 atgaatcaaa ataggtcgat cacctagctc taaaaattgt tttggcaagt tactgattcc
     5461 catgcgtgtg ccagttccac cggcaagaat tcctgcataa atcatctatt ttctcctttg
     5521 tcttactaaa aaaacttatt ctctctatta taccacaatc tagtcctatc ataaaagaaa
     5581 tactggtcct ccccttctag aataggagaa ttatgcagtt ctattattca aagaaactag
     5641 ttcatttcta gtaatgacta ggaattctgt agcaattact aataaatggc tgcgaaattt
     5701 tagagtcctt cagaataata tactttcctt aaagaaaact taaaatttaa gatttgaaac
     5761 ttcaaagtga ttacttgact tactgccctt catttcttat tagctaactt tatgatataa
     5821 tgaaaaacga ggtaaattga atgaaaagta taaaattaaa tgctctatct tacatgggaa
     5881 ttcgtgtctt gaatattatt tttcccatcc taactggaac ctatgtcgcg cgtgtcttgg
     5941 accgaactga ctatggttac ttcaactcag tcgacactat tttgtcattt ttcttgccct
     6001 ttgcaactta tggtgtctat aactacggtt taagggctat cagtaatgtc aaggataaca
     6061 aaaaagatct taacagaacc ttttctagtc ttttttattt gtgcatcgct tgtacgattt
     6121 tgaccactgc tgtctatatc ctagcctatc ctctcttctt tattgataat ccaatcgtca
     6181 aaaaggtcta ccttgttatg gggattcaac tcattgccca gattttttca attgaatggg
     6241 tcaatgaagc tctggaaaat tacagttttc tcttttacaa aactgccttc atccgtatcc
     6301 tgatgctggt ctctattttc ttatttgtta aaaatgaaca cgatattgtt gtctatacac
     6361 ttgtgatgag tttatcgacg ctgattaact acctgattag ttatttttgg attaaaagag
     6421 acatcaaact tgttaagatt cacctaagtg attttaaacc actctttctc cctctgacag
     6481 ccatgttagt ctttgccaat gccaatatgc tcttcacttt tttagatcgc ctcttcctcg
     6541 ttaaaacagg gattgatgtc aacgttagtt actataccat agctcagcga attgtgaccg
     6601 ttatagctgg ggttgtaaca ggtgcaattg gagtgagtgt gcctcgtctc agttactatc
     6661 tggggaaagg agacaaagaa gcctatgttt ctctggttaa tagaggtagt cgaatcttta
     6721 acttctttat cattccactg agttttggac tcatggtttt aggaccaaat gccatcctac
     6781 tttacggtag tgaaaaatat atcggaggcg gcatcttgac ctctctcttc gcttttcgta
     6841 cgattatcct ggccttagat accattcttg gttcccaaat tctctttacc aatggctatg
     6901 aaaaacgtat cacagtctat acagtctttg ctgggctact caatttgggc ttgaatagtc
     6961 tcctcttttt caaccatatc gtggttcctg aatactactt actgacaact atgttatcag
     7021 aggcttctct acttgttttc tatatcattt tcatccatag aaaacaactc atccacttgg
     7081 gacatatctt tagctatact gttcgatact ctctcttttc actttccttt gtagcaattt
     7141 atttcctgat taatttcgtg tatcctgtgg atatggtcat taatttgcca tttttgatta
     7201 atactggttt gattgtcttg ctatcatcta tctcttatat tagtctactt gtcttcacaa
     7261 aagatagcat tttctatgaa tttttaaacc atgtcctagc cttaaaaaat aaatttaaaa
     7321 aatcatagga gtttaaaatg aaacaactaa ccgttgaaga tgccaaacaa attgaattag
     7381 aaattttgga ttatattgat actctctgta aaaagcacaa tatcaactat attattaact
     7441 acggtactct gattggggcg gttcgacatg agggctttat cccttgggac gacgatattg
     7501 atttatccat gcctagagaa gactaccaac gatttattaa catttttcaa aaggaaaaaa
     7561 gcaagtatga actcctatcc ttagaaactg ataagaacta ctttaacaac tttatcaaga
     7621 taaccgacag tacgactaaa attattgata ctcgaaatac aaaaacctat gagtctggta
     7681 tctttatcga tattttccct atggatcgct ttgatgatcc taaggtcatt gatacttgtt
     7741 ataaactgga aagcttcaaa ctgctgtctt tcagtaaaca taaaaatatt gtctataagg
     7801 atagcctttt aaaagattgg atacgaacag ccttttggtt gctccttcga ccagtttctc
     7861 ctcgttattt tgcaaataaa atcgagaaag aaattcaaaa atatagtcgt gaaaatgggc
     7921 agtatatggc ttttatccct tcaaaattta aggaaaagga agtcttccca agtggtacct
     7981 ttgataaaac aatcgattta ccctttgaga atttaagcct tcctgcacct gaaaaatttg
     8041 atactatttt gacacaattt tatggagatt atatgaccct accaccagaa gaaaaacgct
     8101 tctacagtca tgaatttcac gcttataaat tggaggatta ggatgcaata tttagaaaaa
     8161 aaagaaatta aagaaattca actagccctg ctggactata ttgatgagac ttgtaagaaa
     8221 catgatattc cttattttct cagttatgga accatgcttg gagccatccg ccacaaaggt
     8281 atgattcctt gggatgatga tattgatatt tccctttatc gtgaggatta tgagcgttta
     8341 ctgaagatta ttgaagaaga aaatcaccct cgctacaagg ttctttccta cgatacatct
     8401 tcttggtact tccataattt cgcatcgatt ttggacactt ctactgttat agaagaccat
     8461 gttaagtaca agcgtcatga taccagcctt ttcatcgatg tcttcccaat tgatcgattt
     8521 acagacttga gcattgtcga caagagctat aagtatgtgg cccttcgtca actagcttat
     8581 atcaaaaaat cacgagcagt tcacggtgat agcaaactaa aagattttct tagattatgt
     8641 agctggtacg ctctccgatt tgtcaatcct cgctactttt acaagaaaat tgatcaacta
     8701 gtcaaaaatg ctgtaaccaa cattcctcaa tatgaaggag gagttgggat cggtaaggaa
     8761 gggatgaaag aaatcttccc agttgatacc tttaaagaac tgattttaac tgagtttgag
     8821 ggccgtatgt tgcctgttcc caaaaaatat gaccaatttt taacccagat gtatggcgat
     8881 tatatgacac caccatcaaa agaaatgcaa gagtggtata gtcatagcat taaagcttat
     8941 cgcaaaaact gattgagggg gattatacaa actactaaga tagaggttat tcaaaaacat
     9001 aattttagta gaaaatgaaa tacatattcc ca
//
LOCUS       DAVLIK010000066         8888 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLIK010000066 DAVLIK010000000
VERSION     DAVLIK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8888
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.066"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..829)
                     /locus_tag="VXE87_001877"
     CDS             complement(<1..829)
                     /locus_tag="VXE87_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843371.1"
                     /translation="MIELKIGKPSFGFLPYESHIEGILTGNNLNKIDYYLSMLDMEAI
                     CLQYGNKRIYDFFIGRNIQCNNIYREYSSRIDLSSEEALIPFLVDALAKGSFCYLSVD
                     TFCINKYISYKKEHIVHSPLVSGIDLDRNLIKISDFFDFTNYGIVWVPINEFIKGYFA
                     IQKVVEEGDIEETENWILKIEKINICKNKTEICDRMAINKVFKGYVLGSEEVKNSMDT
                     FSYINYRLANHKVFQKQSIVEQNLSVTGIKVYEYLKLYIEESIKEPQVLMRIKNLVLL
                     "
     gene            1059..1873
                     /locus_tag="VXE87_001878"
                     /pseudo
     CDS             1059..1873
                     /locus_tag="VXE87_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
     gene            2232..3185
                     /locus_tag="VXE87_001879"
     CDS             2232..3185
                     /locus_tag="VXE87_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV0843372.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASSNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            3506..3640
                     /locus_tag="VXE87_001880"
                     /pseudo
     CDS             3506..3640
                     /locus_tag="VXE87_001880"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(3878..5297)
                     /locus_tag="VXE87_001881"
                     /pseudo
     CDS             complement(3878..5297)
                     /locus_tag="VXE87_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5553..7403)
                     /locus_tag="VXE87_001882"
                     /pseudo
     CDS             complement(5553..7403)
                     /locus_tag="VXE87_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261804.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(7390..7755)
                     /locus_tag="VXE87_001883"
     CDS             complement(7390..7755)
                     /locus_tag="VXE87_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0843373.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIDKSHCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSY"
     gene            complement(7765..8124)
                     /locus_tag="VXE87_001884"
     CDS             complement(7765..8124)
                     /locus_tag="VXE87_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843374.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSSFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            complement(8560..8832)
                     /locus_tag="VXE87_001885"
     CDS             complement(8560..8832)
                     /locus_tag="VXE87_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843375.1"
                     /translation="MKKVDGYRLLNKPDHAVLLFPLTVIIFVLLGACFFKPHFHNSFR
                     GYYSKIDCGIAIQSTGLQIYGDTVFVDGAIYELNEVTMQILDNEKT"
BASE COUNT         2820 a         1695 c         1428 g         2945 t
ORIGIN      
        1 ttaataatac aagattttta attctcatca gaacttgagg ttctttaata ctttcttcaa
       61 tataaagttt caaatattca tatactttta ttcctgtcac actaagattt tgctctacta
      121 tactctgttt ctgaaaaacc ttatgattag ctaacctata atttatataa ctaaatgtat
      181 ccattgaatt cttcacttct tctgaaccca aaacatagcc tttaaaaact ttatttatcg
      241 ccattctatc acaaatttct gttttatttt tacatatatt tattttttct attttcagta
      301 tccagttttc tgtttcttca atatcacctt cttccaccac cttttgaatt gcaaaatatc
      361 ctttaatgaa ctcatttata ggaacccaaa caattccata atttgtaaaa tcaaaaaagt
      421 cagatatttt tatcaggttt ctatctaaat caattcctga aaccaaaggt gaatgcacaa
      481 tatgttcctt tttataacta atatacttat taatacagaa tgtatctact gataaataac
      541 aaaaagaacc tttagctaac gcatcaacca aaaaagggat taaagcttcc tcactagata
      601 aatctatacg tgacgaatac tctctgtata tattattaca ttgtatattt cttccaatga
      661 aaaaatcata aattctctta ttaccatatt gaagacatat cgcttccata tccagcatgg
      721 ataaataata atcaatttta tttaggttat ttcctgtaag aattccttca atatgtgatt
      781 catagggcaa aaagccaaag cttggttttc caatctttaa ttcaatcatt tttataaatc
      841 tcctaatata aatttacttt catcgaacta aactcaaatt gacataattt ctgtcatcat
      901 tcctgcttta attcacaact attcttatat tatgcaaaaa cttatacctg attaacgcaa
      961 taatataaat ttagagacta accaagatga attcgtcctt tttaacaatt tattcagtag
     1021 acttgttcgg taactgtaaa aagtgttata ctatttttat ggaaacagta tacgacaaag
     1081 cacaaaaact taactcaaaa aacttcaaac tattgattgg tgtcaaaaag gaaacctttc
     1141 aactcatgct agaacacctg aattcagcct atcagattca gcaccgaaaa ggtggacgtc
     1201 cacgtagtct gcccatggaa gaccagctca ttatgaccct ccgttacttg cgatattatc
     1261 ccactcagcg tctgctggcc tttgattttg gcgtcggtgt agctacggta aatgccatca
     1321 tcacttgggt ggaggataca cttcgtgcgt caggtagctt tgatttggac catttagaag
     1381 ccccgagtgc tgctgtggct attgacgtga ccgaaagtcc gattcagcgt ccaaaaaaaa
     1441 ccaaagcaaa aattattctg gtaaaaagaa acgacacacc ttaaaaactc aaattatgct
     1501 ggatttgacg acacataaag tctgtcaaat ggccttttct gacggacata cgcatgattt
     1561 tactctcttc aaagaaagta ttggacaaag tttgcctgaa acgacgcttg cctttgttga
     1621 cctaggttat ttaggcatct tgaaatttca tgagaatact ttcattcctg ctaaaaattc
     1681 caaaaatcgc cgcctgagtg aggatgataa gcagttaaat aaagagatgt cagcgatacg
     1741 aattgaaatt gaacatttta acgctaaatt caagaccttc caaatcatgt cagtccctta
     1801 tcgtaaccgc agaaaacgtt tcgagttacg ggcggaatta atttgtgcca tcatcaatta
     1861 tgaagtgaac tagattctga acaagtctag tataatttta ccacaaagta acatgatttg
     1921 caagcgattt caataataaa gatatatgat tatcctcagg aataaataaa tttgaaagtt
     1981 ctataatgaa gttagccacc ttaccttagt caagaattag atgtttcact atgtttgagt
     2041 aagttgatga tttcatttga taacaggttt gaaactgtta ggctaggtgc ccaaggctaa
     2101 tcatagcctt ggtttagctg aaaaaacagg ttcaagggtt cctgttgtca aatgaaatgt
     2161 gatttaaggt ataagaaaac acctctgtgc tatacttgtt gttcaccaca aacacaagga
     2221 aaggcacaga gatgcaagaa cattataccc caaaagggaa acatttgaca atagataacc
     2281 gtcgcttgat tgagcggtgg aagaatgaaa ataagtccaa tcgtgaaatt gcaggcttgt
     2341 taggaaaggc gcctcaaacg attcataatg aagtcaaaag aggtacaact ttacaacaag
     2401 tgagaaaagg gctatacaaa aaggtctatt ctgccgatta cgcacaaact gtttaccaat
     2461 tcaatcgaaa acggtcggtg aaaaagttaa ttttaacaaa ggaaatcaga gagaagatct
     2521 tacactatca taagcaaaaa ttttcgcctg aaatgatggt taacaagaag caagtgaaag
     2581 ttggtatttc aaccatctac tactggtttc ataatggtca tttaggattg acgaaggccg
     2641 acatgcttta tcccagaaaa aggaaaggtg tcaagaagca agctagttcg aactttaagc
     2701 cggcaggtaa atctatcgaa gaacgtcctg acgttattaa tcttcgcttg gaaaatggtc
     2761 attatgaaat tgataccgtc ctactgacta agataaaaaa ttattgcctg ttagtcttaa
     2821 ccgaccggcg gagcagacac caaattataa ggttaattcc aaataaaact gctgaatctg
     2881 tcaatcaggc gcttacgtta ctattagggg agcatcgtat tctgtccatt actgcagata
     2941 atggttcgga gttcaaacga ttgtctgagg tatttcctga ggaacatatc tactacgcac
     3001 atgcttactc ttcatgggag agaggttcaa atgaaaatca taatcgatta attcggagat
     3061 ggttacctaa aggaaccaag aaaacgactc cgaaagaagt agcttttatc gaaaattgga
     3121 ttaacaacta ccctaaaaaa tgcttggact acaagtcgcc aagtgaattt cttttgggtg
     3181 gctaacttca acttgaaatt tgggctttgt ctctatgcta aaggaatccg ctataaatac
     3241 aagtactata gccgtcggca ttcctcatta acacgaccca atttgattaa tcagtgtttt
     3301 caaacaaaag gtaaaaatga aatctggctg ggggatttaa cttatattcc gacaaaagca
     3361 ggtactcttt atttatcatt atatatatgt ttatagcaga aaaattgttg gttaggcaat
     3421 gggaaatcga atgcaagata agttggtaac gaatgttttc aatcaagctt atcatagaga
     3481 aaatctcaaa taagaactag tcggccatac cgatcaagga tctcaatata ctggagctag
     3541 atttcaagaa ctccttaaac agaaaagatg caagtctagc ctgagtcgaa aaggcaatcc
     3601 atatgataat gcacccatgg aatcctttta caaaacataa aaagagaact tgtcaatgat
     3661 gccaatttcg caactattga acgaaatctt taaatatatt gaaatctatt acaatcctaa
     3721 atatctccat tcggcattag ggtaccaata actaatagag tttgaaaaaa atagtcacta
     3781 atcatcgagt ccactgaaaa agtaagctct acagttcaac taaaatgaaa aaagagggat
     3841 ctatctcctg cttggataga ttcctctttg cttttcctta tttttggttt attagagtta
     3901 taatcctctt catattaacc acaaatatgg ttgtggcggc ttgtaactcc atgtttaaaa
     3961 gacctggtgc tctagctaca ttaagaccat gtctgttttc aagttccgca tttttggctt
     4021 ctatcttgta gcgatgtttg gccttttctt taaaataggg cgcttcctga aacctcttct
     4081 ggaaaatatg ttcatcgctc ttaaggggta tcaaataagt cttagactta gccccttctt
     4141 tataacagcc catatttgac agtgcttgat gtcaaaatag tgggtttcct gagccgtcct
     4201 tcttcctgtc ttttccttct ttagtgccat atgcccttct ggacaaacaa agagacctgc
     4261 gtccttgtta tagaaaaact catcttcctt cctacgaaag ccttttgaaa tagttggata
     4321 tggcctagcg actcaatgca cacgttcttt cttggtaaat tgcatattat ccttcccaga
     4381 gtaggcccta tctccaacaa tagcttcaat cgtcacgcca ttatccttag atttgtgata
     4441 gagttcttct aaaacaggac catcactttt ttcacccgat gtcaccacac aggcagtaat
     4501 aatccgttca tcggtcatgg caaaatgctc tttgtacccg taaaaggaac tatcggctga
     4561 cttatgtcca attcttgctt cttctttgac agaggattcc aagtgctcta agtcatcctc
     4621 tacagcttct ttaaggtaat tgaattttgt gagatagctg gtattccagt caattcgtca
     4681 tgcttctcaa ggactgatat taattcttgt gtatatctta attcagctac tagagtatct
     4741 tcctgaggct tactaggaaa ttctgccttg atatattccg aatactgata aatcgtttta
     4801 cgcaaggctt ttgagcgttc tcggaggact tcttgaggtt tcttgtgatt gtaatgaact
     4861 ttggtatgag tcgcatccac aatgagaatg ttacttttaa tcagaccgag ctctatcgca
     4921 atctgaacag atttagcgat gagcaaatca agtaatcgtt catctttgtt ccgaagtttt
     4981 cggaatttag tcaatgagga cggttcaata acaggagcta gaccaaggaa gtatttgaag
     5041 gtcataccag aaaaggagcg ctccaccaca tccacatcgg acaacttata gatgtctttt
     5101 aataagagat acttgaacat catgataagg agagagtagg aacgacatcc gaagtcaggt
     5161 tgataattct tttccagctc gtcataaata aaactaaaat cacagagttc cattagctgt
     5221 cgtaaaaaat gagttttggg aacaacaata tcacacagag tagaataggg actaacatcg
     5281 attatcaagc ataccatcac ctcatcttta gtataccatc atacgatgac tttttcagtg
     5341 gactccgaat tatcttaact cttgacaagt ccagtgatgc aatgatagag catagacaac
     5401 tttaatgatt tggggtcgaa gcgtaatcgt aaaataggta aaatcgtctt tgaatgcatt
     5461 tttattaatg tttgttttag aagttaaacc gatattggca accataaaca gaaaagatat
     5521 ccaaaaaaat ttgagtttgt cttcagtctg atttatattt cattcataat ttctttattg
     5581 atacactcat caaaaacctt aaataattgt ccaagctttc ttattgtttt ctcatactca
     5641 tcaagaacat taccaaattc ctgttgtaac ttcaaaagtt cttcattgac ttgttctaaa
     5701 gttgttgatt ctgtcatgtt caatttagaa aattcatgcc tagctagttt ttggctaccc
     5761 gaaccttcac tcttagaatt gataagtact tccgccatct tatttaaggt ggcaattttt
     5821 tcatttgttt gagtcagttt tatatctagc tctgctattt cggaaaccaa gttgtcttta
     5881 atgtcttggt atttcttatc tgtctcagtt aactcaatca agaggctaat ctcagaaatc
     5941 ttttcttgaa gtctttcaac agtcggtctt ctgtatggta ttactcgact atcgttggtt
     6001 agctgcctaa tcaaggttct ccctttgata tactgattct tatccgaatg ttctttgtta
     6061 tagacaaaat atgaggttgt ctcacgaatg tagactttat attttttctg attttcttct
     6121 tccataatat ccagttgata gttaggaatg aaaataagac cactctgatt tataccaaag
     6181 gacactttga tataaatccc ctcatcaact aacttctcaa tttggtgttc tgtaagtttt
     6241 acttcaaatt catgaacggc atctcgtttt tccttaaatg tctcaaaggc ttcctcaatt
     6301 tcttcagtag ataccttctc cttatctcgt tcttcttgaa aagcacggta ctgtgcctgt
     6361 agattttcta ttccttctga aacacctact tccttatttt taaaataatc ttgaaaaaaa
     6421 ttgacatcat ataatttctc atcacttatt tttttatgac tcagactgaa ttgctttcca
     6481 ttttcttcaa gtataaagat tacatttttt tgttttaagt caatggttag attcaattct
     6541 tttgattttg ttagtaaccc ttctaaagaa ttgacacagt tcaacaaaaa ttctaaacga
     6601 cttgcaatct cttgcttggc aaaatgcatt ctaaaaaaat cttcatcata taaatctcgt
     6661 ttactgagtt gacgtcctcg aattggtttt gtcattgccc gatccgtcat catgaatcga
     6721 ctatgcttct gactaaaatc aatctgaaca tgcaactgct ttgctttctc taaaaaatca
     6781 tcaaactatt tagattgctg catcaaaaaa taaagacgtt gtttcaattc aaacttatga
     6841 ctagattccc tatatttttt ataacctcga taagaataac gtttctcaat aatttttgca
     6901 ccagccattt tagaaatacg gtctgaaatc atacggaggt ttcgttccaa ggcatagttc
     6961 catatcaact ttttatctga attgcggtca atagcgttga ttaggatgtg attatgaaca
     7021 tgatctttgt ctgtgtgagt tgctacgata aacttaaaac gacctcctgt caattccatc
     7081 atggtctcat aaccaatgcg gttaatttct tcaggtgtca gattatcttc aggagaaaat
     7141 gattggatga gatgatgggc atgaatagtt tgttggtgtt tttcttgtcg gtcatttctg
     7201 gactcgtaca acttgtcgtt attagtaaag ttaacattgt acatttctac catttctgta
     7261 tggctaggaa aatctaagta attactcatg ccaaaatcag atactaattt tagattatct
     7321 gttttatctg gattgaggat atatttaatc aaacgcctac gatatttttt tccgtgcgtc
     7381 gcaaagtgtt tagtaactac catgaaactc cttcagtctt ttcacctcca cttgaaattc
     7441 tttgtccact tccttaatta actctccgac tcctttactc aattcttgta actgttcctg
     7501 agaaatcaga cggctttgat tgatagcacg cgcaatttga ttaatgttat ttccgatccg
     7561 tctcaattca aatactaact ggtcataggt atccgtatta atggtgacaa atgacatatt
     7621 gggattcagc aacactttcc tggcatagac tgaaaaattt tgacagtgac tcttatcgat
     7681 tcgctcattc aattgatgta attctgaatc tgttagaaat acttttttga gattggtacg
     7741 ataacgataa accatagtag cctcctatct catgtatttt tcacgaaacc cacgactgag
     7801 tgactgtact tgattgactt ccgcaatcaa ttcttgaacg caggtcaata agattgacac
     7861 gtgttcttga gtcacttggt gattctctct tgcgataatc aaaaccaaat gcacatctcg
     7921 actgatctgt tcaaactttt gagactgcca aagggaaaac cattctttgg cagctaactg
     7981 tttgtcatca gtcatcaaaa ttttatccct gacgaatgat gaaaagtgac gataattatc
     8041 aacctccatc attttttcaa tctgttttag ctcatctgcg gttagattta cctcttttcg
     8101 aatgtcacgg tactgttcag acatctcttt tcctcacttt catcctttct cggataaacc
     8161 ccgaccccgt gtgtcatacg ggaaatttct taaagtcctt gttcggtctt tgcgagctca
     8221 ggcattgtgg tcacaatacc caaaaaatca tatcgccagc taaccaaaac cttccagttt
     8281 tgacagctaa ccataagata acttggtggc ttcgccccca aacccccagt gaaaaattga
     8341 ggttttattt tcttaggaat gatattagga caacagggat gatttggaaa aggtatcaca
     8401 ttattgaaag gaaggtaaga aaaaagagag caaaagctct cataacaatc catttaaata
     8461 ctacagagta gttaaaaatt agtaactaat attttatata ataagaatct ttctctgtct
     8521 tattttttat aacaatacct tttttatcaa atgtacctat cacgtttttt cgttatctaa
     8581 tatctgcatt gtaacttcat tcaattcata tattgctccg tctacaaaaa ctgtatcacc
     8641 ataaatttgt agtccggtcg actgaattgc gataccacag tctattttac tgtaataacc
     8701 tctaaaacta ttatgaaaat gtggcttaaa aaaacaagca cctaataaaa caaatataat
     8761 taccgttaaa ggaaaaagta atacagcatg atcaggctta tttagtagtc tatatccatc
     8821 aacttttttc atagtaggaa gcttttttaa tataacagac ttatcactaa cataataatt
     8881 ttcttcta
//
LOCUS       DAVLIK010000067         8353 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLIK010000067 DAVLIK010000000
VERSION     DAVLIK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8353
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.067"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..3749)
                     /locus_tag="VXE87_001886"
     CDS             complement(<1..3749)
                     /locus_tag="VXE87_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0843376.1"
                     /translation="MDALTRRQFDRSMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKHIKQQGGIEAKIQAQIEATDKDFDQKVDKIKKDFNDQVELAKAKAEEVKRE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELAGASSLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEA
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQV
                     GGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVSDSPATGFDKAIRLTSSNARD
                     QIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISPIFTLKDENWTKL
                     SFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLATSSKEAPEDIEGQISTV
                     ESTFKQRANSLEAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLS
                     QAEFEVRAGSIHQEILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQD
                     ISKTGIWTTSTYTAAIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIP
                     GSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNES
                     KQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANSL
                     DAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSI
                     RQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVT
                     GQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGR"
     gene            complement(3754..4104)
                     /locus_tag="VXE87_001887"
     CDS             complement(3754..4104)
                     /locus_tag="VXE87_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843377.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGARTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            complement(4113..7706)
                     /locus_tag="VXE87_001888"
     CDS             complement(4113..7706)
                     /locus_tag="VXE87_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843378.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDRVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWDQLDFQTQQQ
                     IRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSIATIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLAYAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFAETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITLVIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIGNIFGNLGSWFGGRWNDSKNALAEANTWLGDKFKS
                     GRDKVNSAFEKVGSWFGDRWNDIKDGVKEADTWFGEKFESAKKKTQNPFQKIGSWFGD
                     RWKDMQDALKEIPNWFKNLFNDAMDNAKNIVKSGIDKLKSFFNFDWSLPKIKLPHFNI
                     SGSFSLMPPRIPSFSVDWYARGGVFNSPSIIGVGEAGQEAVMPLERNTGWISILAQKL
                     AERMPANNVPTGYSLPAGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
     gene            complement(7693..8043)
                     /locus_tag="VXE87_001889"
     CDS             complement(7693..8043)
                     /locus_tag="VXE87_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843379.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKTQERKEKIIDSYR
                     LSQMISNHVSLLLSNDAKIVEFWEYAPELFVEEQQAVELERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            complement(8082..8342)
                     /locus_tag="VXE87_001890"
     CDS             complement(8082..8342)
                     /locus_tag="VXE87_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843380.1"
                     /translation="MPEAGEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYV
                     DNGGDQTTFMTEVLMPLFEVSGFTPRGSKNKKTSKKKMTVVE"
BASE COUNT         2183 a         2073 c         1555 g         2542 t
ORIGIN      
        1 tttcgacctt ggactacatt ttcgtacttg atccaagcgc taaaagtaac tttttggtac
       61 aaccttgagc tgaaatctgg ttcaaggttg aacgttaaag tagagttgtt ctctagccta
      121 tagcattctt tttgacctgt gacgtggttt tcaggtaatt tttcaattac agctccaacc
      181 gtcttggatt ttatccatag attccggcct cccaccttca tttttgaaaa ttcttcacgc
      241 aatttcccag cttcagatac aactaaagtc ttatctgctt tatccttggt tgcgttcagg
      301 atttcctgac ggatagagcc agctcgcacc tcaaattcag cctgactcaa cttctgattt
      361 agtttgttct gcgtgtctgt ctcaagactc ttcacagatt gccggatatt ttcagcagtc
      421 acattgagtg agctgatatc ggctttggtt ctaaggcctt cagtcagacg gcttacacca
      481 gcgtcgagtg agttggctcg ttgtttgaag gtcgattcaa ctgttgaaat ctgaccttct
      541 atatcttcag gagcttctga ataagaagta tctacatcgc ttatttcaaa cttcggcatc
      601 caaatccaaa cggttccttc ctggttgaaa ttgaacaacc attcatttgt ggtctgcttg
      661 gattcgtttg tccaaccttt tggaatatgg acaacatatc gtttaatttc tgtcgacaat
      721 gtcacatttc cagttttata tccgatattc cctaatcgag atcttagcat tattccattt
      781 ttatttgcct tagcataaaa actaatggtt acatcttgat tagtcgtact tccgggaatt
      841 actttcccga attgacccag agctgggtaa gtaaccttgg gattccctcc atcacggcca
      901 gatggattca gacctataat tttaagagcc ttatgtccaa gatacttact ttcgctatcg
      961 atagcagccg tatatgtact cgttgtccaa attcctgttt ttgaaatatc ctgcttgaat
     1021 agtgagttca agaatagatt tcgaccggat gcctgcacac tcgcaatccg actagccagc
     1081 tcctcagctg tctgcgtgag ttctgacttg ctggctttat ccttggttgc gttcaggatt
     1141 tcctgatgga tagagccagc tcgcacctca aattcagcct gactcaactt ctgatttagc
     1201 ttgttctgcg tgtctgtctc aagactcttc acagattgcc ggatattctc agcagtcaca
     1261 ttgagtgagc tgatatccgc tttagttcta agcccttcag tcagacggct tacaccagct
     1321 tcgagcgagt tggcacgctg tttgaaggtc gattcaactg ttgaaatctg accttctata
     1381 tcttcaggag cttcttttga gcttgttgcc aaacttccgt cttccagctg gggcgcaaga
     1441 acatctaaat attctccgac ctcagcattt acgagataca catagccaat tgatgcgact
     1501 ccagccctat ttctagcgct agtaaacgat agctttgtcc aattttcatc ctttaatgta
     1561 aagatgggcg aaatacccga attatcattg acttgccaat aagtttgtag cttgaccttt
     1621 tgacctcttc tgcctttgac ccaacaagac atcgtgtatg tgccttgcga gatataaaat
     1681 ccatcttgag caatacctat ttggtctcta gcattgcttg aggtcaatcg tatcgcttta
     1741 tcaaagccag ttgctggact gtctgataca tcaatcgtct ttgccgtccc agcgcctgac
     1801 ggtctaaaag tacctgatgc ccacaatcct ctggctagca tcatgcgctt tgtaccccgg
     1861 atataattcc tacccccgac ctgcacactc gctatccgac tagccagctc ctcagctgtt
     1921 tgcgtgagtt ctgacttgct ggctttacca ttggccaagt tggtcagttc tgaaagtcta
     1981 cgagtcgtcg tctcctcata cgtcgcttgc gctgacttca cgccagccag ttcattttta
     2041 gtccggctaa gtgcttcaac ttgcttggca atctcagctt cagcctgtgc ttgcttcggt
     2101 cgaatatcgt ttgcgatagt tcgttttaga acatccaagt cacctgacaa agccgtctga
     2161 gcgctcgtag tctgcgactt aaacgcttca agtctagcga cagaatccag ctcaatccgc
     2221 ttagcttcct gagcgagtaa gctacttgcg ccagccagtt catttttagt ccggctaagt
     2281 gcttcaactt gcttggcaat ctcagcttca gcctgtgctt gcttcggtcg aatatcattc
     2341 gcgatagtcc gtttcagagc gtccaagtca cccgacagag ccgtttgtgc gctcgtagtc
     2401 tgcgacttaa acgcttcaag tctagcgaca gaatccagtc caatccgctt agcttcctgt
     2461 gcaagcaggg tacttgcgcc agcatttcgc aaagcttcct cagccttgcg cttagtttct
     2521 ttcaatggcc cgttgtcaaa gctattaaat cgctgattga tagtgtcaga cagttctctc
     2581 ttgacttctt ccgccttggc cttggcaagt tctacttgat cgttaaagtc ttttttgatt
     2641 ttgtcgacct tttggtcaaa atctttatct gttgcttcaa tctgcgcttg gattttcgct
     2701 tcaatgccac cttgttgctt aatatgcttg gtaatcgtac cctcgtaaga atactgagta
     2761 tcgtttccag ccttactatc tgcgctgata cgccctctca gaccaccttt aaaagtaaag
     2821 ctctgactta acacaggaac tttaaaggtc tctttcttat tggtctgaat ggttacccac
     2881 tgcccgacct caagcagtaa atgcccttgg tagttgagat tatacggata gtaagttagg
     2941 tttttcagtt tgtaatacag gtcatttaaa gcgctctggg tcatgaagac attgtccagt
     3001 tccaaagacc ggcccgtctt cataccgacc gtcagagact tcttgtccgt cttacaagtg
     3061 ataccagcta tctgatactc aatctcactc ttggtcaagc catgcaagaa gtaactgtca
     3121 gcgttgatcg tgatattgga ctcagtcaaa tcacggattt ccatcttgcc ttctctgttg
     3181 aagaaacaag acatcccaat catctgagtc atagcgctca gcatatccct aaaggaaagt
     3241 ttcttgccct caggaacttg ctcaatatga taacgcatcg cgctgattcc gaaatagtca
     3301 ttcgctaact caatgcctgt tttcaggcag atttcctgaa taacctctcg tacttcagct
     3361 gggaaatgca agtccgtcac gtactcacga ttgagcttaa acataccgtc cataagttca
     3421 agcgtggtag tgtttcggtt tcggtcaatc tcaatatcgt tgatgaagta ttcccccatc
     3481 ttgacccact ggtaggtatc cccaaccagt agaccaatct cagggtgcag ggtatccagc
     3541 ttattgaacg tggtaatgat actggtaaag gtaattttac cgctaccagc gcaggttcca
     3601 ccaggcttat aagtatcgcc cttgatgtag ccatactcaa aactagcctc tttgatatcc
     3661 cgtgaagcat attcaccaac acgaatagcc agcgtccttt ccttggcaaa catagatctg
     3721 tcaaattgtc gtctagttaa agcgtccatt ttcttacctc tctaccagat taaatttagc
     3781 gccagaccaa ggtttaaact tctcagtaaa ggtatagcta ggagctgtcc tagcaccgac
     3841 atagaaagtc tttgtgactt ggccatccat ggggtctgga taagatacct caaaaaattc
     3901 agatgataca gcatgtaaaa gctgacttat ttctccctga gtcatcatac cccattcaca
     3961 gtctagtttg cgtttggtcg tgatacggtc acgcaccatg tcgccattgg cattacgccc
     4021 tgtctctcca tcgatatctt gaataccgac ttgaaaagat ttgggaggct tcacagccac
     4081 cccattgatt gtcaattgtg ccatttaacc tcctaaatct tgagcaaggt ttgacctgct
     4141 cgttcatgtt ccttgttgat ttcttggata gctacccgtc cgaactcatg gcctgcgatt
     4201 tggataacga tgtcgccagc cggtaatgaa taacctgtag gtacattatt agcaggcatt
     4261 ctttcagcca gtttttgagc caagatagaa atccatcctg tattccgttc aagaggcatt
     4321 accgcttctt gaccagcttc tccgacccca atgatgctag gagagttgaa tacaccgcct
     4381 cgtgcatacc aatctacaga gaatgatgga attctaggag gcatcaagct gaagctacca
     4441 gatatattaa agtgagggag tttgattttt ggtaagctcc aatcaaagtt aaagaagctt
     4501 tttagtttat cgataccact tttaacgatg tttttagcat tatccattgc atcattaaac
     4561 agattcttga accagttggg gatttctttc aaggcatctt gcatatcttt ccatctatca
     4621 ccaaaccaag aaccgatttt ttggaaagga ttctgagttt tcttttttgc actctcaaat
     4681 ttctctccaa accatgtatc agcttctttc actccatctt tgatatcatt ccaacggtca
     4741 ccgaaccaag agccaacttt ttcaaaagct gagttcactt tatcccgacc tgacttgaac
     4801 ttatcaccaa gccaagtatt tgcttcggca agtgcgtttt tagaatcatt ccaacggcca
     4861 ccaaaccaag agcctaagtt gccaaatata tttccaatag cgtcccatgc ttgctggaat
     4921 ttctcgccaa accattgacc tatcggctca aagatttctt gtagtttcgt ccatagaccg
     4981 ctgaaaaatt cgccaatcgc ttgacaaata ccactgataa aatcacatag tccttgccat
     5041 gcagttttag caaactcaac aacagtgtcc caattttggt agagcaaaac accgatagca
     5101 attaaggctg caatagcagc aataactaag gttattggac ttgtcaaaac tgctaacgct
     5161 gcattaaaag cccatgttgc agctgtagcg actcctgctg caacagaatg tgcaaattcc
     5221 gccgcggttg ctaatcccat tttcgctgca tgagcagtcc atgctagagc tgatttacca
     5281 agttctaaag cagtttttcc tagctgtgca attgttttac ctgaattgac cacaaaatct
     5341 tttgcatata aggtgttcaa atagattgtt tcagcaaaac tgaccaactt atcaaatgtc
     5401 aatgctttaa tagcaagacc tagattctta attcctccaa caatcaaaga gaccttacta
     5461 cctaacaagc tgaatgctcc tgcaagtcct ccagcttgtt ctgcccatga taagaaatta
     5521 atcgtttgcc aagttgttat caaagctacg ataggttctt tgttttcttt acaccagtca
     5581 gaaaaaacgg tgaaaccatc tgccactaac ttaatagcat acgccaatag tcccaaagtg
     5641 gctaaaaggc cacctcctaa taaatctgaa attccttcaa tactaacacc gaatactcct
     5701 gataaaaact cagcaaaagg ttgccaggaa ttctcccaga gaatctgaat aatgtcaatt
     5761 agcccattaa aagcattagc aatagagtta atagcaggga ctacatgttc atcataaaca
     5821 cgacttaagc catcgccaaa tttgttaaca gacctttcaa tgctctcaaa tacaggcgca
     5881 acagtatcta ataaactttg gaagactgat gaaattttag gagcgcttgt cacaacgact
     5941 ttttcaaaac ctttaaacaa acttcctgct aatttactac caacttcaac aatggtagat
     6001 gtcaaactca acagagttga cacaatagcg ctaccgatac gaaccgcacc agttgaggta
     6061 atgacgtcgt agaaagcact agaaaagtcc tgagctatgt ttcctactgc ctcggaaagg
     6121 ttaccaacat tatcaaacaa agcgactagc gccctggtaa tgcgttcttt ttgccttcca
     6181 aggccatttg caatactttc ggcaaggaaa acaccgatac ctagcccgat agtagctatt
     6241 gagcctgtca cttgccctaa agcataagca attttctcag ccattcggtt aaaggcattc
     6301 acaacccttg ggtcagtggc gatttctccc attgtcttag ctatttggtc taaggcagtc
     6361 ttaatgcgtt ttataccttc tggtctaaat gctgcatcaa aacctttctt gaagaggtca
     6421 aacaaccctt tgagcttatc tccaagacca tcaaaaatgc tcttgaattt gttgtccatg
     6481 tcagtcaact cgacttctgg caagatgtct ttgaaaggtc cgccaccgcc tccctttcct
     6541 ttaccacctt tgccaccgcc tccagaaccg cctgcgtcgt catcttttgg tttttgcaag
     6601 atgttaatct catcaaatcc caaaagacct agcaactctt tagcagcttt cttagcgttt
     6661 ttggctgagt ctccaagatt gtcagcaagt cctcctgctg aatctccagc gtcgtctact
     6721 gcgtcagcaa ggtctcctgc tccgcctgca gcatccttca tggcgttacc catgtctcca
     6781 actgctccac caacaccatc tttcactgtt gctttcttgt tgaacatcaa agcaataaac
     6841 tcagcgagtt tagcagtaac gttcttcaaa accatagcaa aagagttcaa gacaggcata
     6901 atggcattga taatcggtaa catagagtta ccaaggttca atgctgcgtc cttcattagc
     6961 gacttaaaca ggctgatacg accatttaca gaattagaca aggtattccc atacttggct
     7021 gtagcttgct ccaggatagc cataaggcgg atttgttgct gggtttgaaa gtcgagttgg
     7081 tcccaacttt gaccatttga gaaacgttta aaagcttcag tggacttaat catagccaca
     7141 ttgacgttga ttcctaggtc ctcaattgct tcggtgttcc ctagtagacc tgagcgaatc
     7201 cgctccataa cgtctgtaat cgtgcgccct gaaccttcag caaccactgc cgatgtctgc
     7261 aacatcttag cagtataagc acttagcttg ttggtatctt tgataaaccc agaaaataag
     7321 tttgagtaga ccgcaccgta gttagtagcc tcacccacac ccatattcat agcgttggcg
     7381 ttatcgttaa cccattttaa gaaagattgc gaactctcgc ccatctgtcg cttgatttgg
     7441 ttcatagacg ctgacacttc aagagctgtc tgcgttgaat acatcccaac atcaagtaat
     7501 ttcttaccaa ggattgcaaa accagcgaac ttagccagct taccaaacgc actaccgatt
     7561 gagttcgact gttcacgaac tttggcagta gcatttttca ctcggtcaga tgttcctttg
     7621 acctgattct cgacttcttt catctttttc ctgaaaggcg ctatctcagc gtcaatcatg
     7681 actttcaatt catcaagagt tgccatttac ttcctccttc ctttttcgat tatgtctctc
     7741 tgcaaattca cgcatccgtt ccttatgcaa caaaagtgct tgtttctgtc gttccagttc
     7801 taccgcttgt tgttcttcta caaataactc aggcgcatac tcccagaact caacaatctt
     7861 agcgtcattg gacagtaata aagaaacgtg attggaaatc atctgcgaaa gtctgtatga
     7921 gtcaataatc ttctctttac gctcttgggt tttgacacgg ttgtagcttt caatcatttc
     7981 tctgatttca agcaccgtca aatcccaaaa atcaagaggc ttgcctccaa tgtccaaaaa
     8041 cataggataa agcctctcaa taatctgcgt tactgttaag attactcgac tactgtcatt
     8101 ttcttcttgg aagttttctt gttcttgctt cctcgtggag taaaacccga tacttcaaat
     8161 agtggcatta aaacctctgt catgaaagtt gtttggtctc ccccattgtc cacgtactca
     8221 tcgtatagat catagacatc ctcaagagaa tacccatgtt catactgctg caaggcgccg
     8281 tgaactaaca acaacataac tttcaaaggt ggcaaagtga actcttcgcc tgcttcaggc
     8341 atgaaaatct tca
//
LOCUS       DAVLIK010000068         7894 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLIK010000068 DAVLIK010000000
VERSION     DAVLIK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.068"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(169..4011)
                     /gene="spuA"
                     /locus_tag="VXE87_001891"
     CDS             complement(169..4011)
                     /gene="spuA"
                     /locus_tag="VXE87_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0843381.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATSPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVDAKKEDILKHSNITNHL
                     GNKVTITDVAIDETGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLREEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRKESVENSSKENISATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            4428..4841
                     /gene="rpsL"
                     /locus_tag="VXE87_001892"
     CDS             4428..4841
                     /gene="rpsL"
                     /locus_tag="VXE87_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0843382.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            4861..5331
                     /gene="rpsG"
                     /locus_tag="VXE87_001893"
     CDS             4861..5331
                     /gene="rpsG"
                     /locus_tag="VXE87_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0843383.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            5756..7837
                     /gene="fusA"
                     /locus_tag="VXE87_001894"
     CDS             5756..7837
                     /gene="fusA"
                     /locus_tag="VXE87_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0843384.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
BASE COUNT         2174 a         1584 c         1752 g         2384 t
ORIGIN      
        1 tttgaaaact tcaaaaaacg gatttttatc gccctgaata tcaaaaaaga aaggacaaaa
       61 tttgtccttt ctcaagctta gctttttttc aacccactac agttgacaaa gagccaatta
      121 atcccccgag ctataatgct tgggggattt ttctatagga gggctagctt agttctcttt
      181 tttatttttt agtaagaaac cgagaccaag gagcgcaagg aggctgattc ctgcaaatag
      241 gagtttgttt tcgtttttga ttcctgtatt tggaagttca gcttgtctat ctggggttgc
      301 agatatattt tccttgctag agttttctac cgattctttt cgaaccgctt cttttacaga
      361 tgatgcttgt gcttcttgtg ctggttgttc agcttgtgaa tcagctgtag cttggctagg
      421 tttattttcc gcatcagcta ctttggcatc tggtttagta gaatcaggtc tagcttctgg
      481 agctgggtct tgatgtgcag ggtgagaagc ttcattttga tgttcaggct tggaaggggt
      541 tgagtctggt ttctcttctg cagttgactc atggctagtt ccattttgag agactcgaag
      601 aacagtagct gtaagggcat tcaatttcaa gcctttttca gtccattcaa gtcctttcgg
      661 gttggcaatt ccgactgatc ctgcttggtt ttcatctgcc aaaacttccg catttcttag
      721 atgtgcaaag gcagttccca aattaaattc gcgagctttt tcatccgcat tgacaaagac
      781 tgcgtagata tcgccgtttg gagcagtgat ttggtagcca atcactacat cctctttttc
      841 cacaccattt tggcctggga cagtgatgag gtggacacgg tctttgatat cttggagact
      901 cttaagtcgg aaggcatctg tagattgacg aagggcaatc aaacctttca tatagtcacg
      961 gctcttgaca ttttcaggat aagctttacc atctgtagcc ttagtccagt caaacttgtt
     1021 gactgcgtcg ctagaatcgt aagaatcatg gatgaagtaa ggatagtcaa atgggttgcc
     1081 gtccttatca cgcaacaagt gagatttgtt tggaacctta tcctctgcta ctggagtctt
     1141 gtaggctggg tcacggaatt gtttagtacg tccatattcc tgaccggagt ggataaatgg
     1201 agttccttga gctgtcaaga ccatgagatt tccaagtcgt aaacgacggt ggatttcagc
     1261 atagttctca gccttgcttg ggtctttttt gatagactgg gcaatgatgt caaagagggt
     1321 caagttatca tgggctgcga tgtattggat gacatctcca gggctgtcag cttcaaagtt
     1381 agttggttga gcaatgagat ttttaaagat ggtgttgaca tcacgcttgc cacctgtgat
     1441 aaaggcaggt tgaccttcgt ttggataacc agatttgagg ttgttacgga tgtcatctga
     1501 aaagacagcg acagtatcgg tatgtttcat ccaatcttgg tcagcagctt tagtaggcat
     1561 gttttcatca ccggcatagg ttctccaacc ttcgcctaac atgattagat ttggattgag
     1621 ggcgcgtgca gccttgtaag cttcttcgat agaagcggcg tcatggtctc ccatcatatc
     1681 gaagcggaag ccatccactt tgtaggtatc aactaggtat ttgatagagt caactaggag
     1741 ccgtttggtc atatggtggg ttgtccccaa gcgtccacca ccaaagctag ttcgaggtgt
     1801 gccatcggca tccataaagt ggtagtagtt tggctctagg tcttcaaaga tatcgacttt
     1861 ggctgtgtgg ttataaacga catctaggat agctcccata ccacgtttgt ggatttcgtt
     1921 gatgaggttt ttaaattctg cgattcgttt ttctggattc ttaggatcgc ttgagtacat
     1981 accagtcaag gagaagtagt tttgagggtc atatccccag ttgtagttgc tgttgcttga
     2041 agcatagtca gacaagcgtt catggttttt caattcattg acaaagtagt aagacaagac
     2101 tggaaggagc tggatatggg ttacacccaa gtctttgaga tagtctagtt tttcaatgaa
     2161 ggcttcaaaa gtcccaaatg gtttggtcaa gtcttttgca atggcaggat ctgaagtgaa
     2221 gtcacgcaca tgagcttcgt agataacggc gtcttcacga gtcttgaaat tgtgaatctt
     2281 accataagtc aagtcttgag gtccgagttt agctggatct acaaaggcgg ctttagccac
     2341 tttatgggca tcgtcaatct tggcatcgtc gctattccaa gcagcaagag atttagcgta
     2401 aggatcgagt gcaagaacag ttttaccttg acgctcgatt tggtattgat aatagtagcc
     2461 agtgaaatct gtgattccga gtttgtttgt gctgtctaga gtttgtttcc aagttcctct
     2521 ttcccctttt tcgagagcga cagttccaac tactttgtca gggtcattct tgtcgtagac
     2581 aacaacagaa accttatcag cacttggtga ccaaagggtc aaatcaactt gttttccttc
     2641 ttctcttagg tcagctccca gtttgccatc atagctgtat gtctcatctt tcaggcgcca
     2701 gcttgttttg gtagtgaatt gatcggaatt gtagctaaca gtataaggat gttttgtgtc
     2761 agagaaatct ccgctgtagg tcactttctt accagtttca tcgattgcaa catcggtaat
     2821 agttaccttg tttcctaggt gattagtgat gttggagtgt ttgaggatat cttctttttt
     2881 agcatcgaca agtgttgaaa agctactttc aatgctagaa gtgcctacgt gttgggctcc
     2941 tgtcatacgg atatcatgga catagtatgg atttgtgtaa atcgattcat catcgtcttt
     3001 taggaaaatt tggctatgat ttttcaaatc tgtgaactta taattttctt tacggatttt
     3061 cacgtcgtct ccttgtttgc tctcatctag taataaaaat ccaaattctc ttgcggcttc
     3121 attaagagga atgtcgatat agcggccata tttgcctgta gccgtaaagt ctgttccgtc
     3181 aggccattga gcgctacttg gattttttac atctccccag taccagagag atttcttgtc
     3241 atagttgcca tctgtgcggt agtagttgac gcgaacagtt cctgcaggct gtggctcgta
     3301 agagaaaacc ttgtaatctt ggtctaacca agcttcgttc atttttggaa ctagtttttc
     3361 tacagattta tcgccggtta gattttttcc agctgtattg ttgatgagga agctaatttt
     3421 cttggcttgt tctcccttta atttgacatc taggtaatag ccgtagtcat ctttcttggc
     3481 atccttgaag gacaaagctc cgtttggcca gttttcagat ggtttttcaa catcgtccca
     3541 agtccatagt ccttgagcat ccttgttttc ttcaggaagt tttttgacat ggatacggaa
     3601 gtagttatct tcgatgggct cttctgcctt agtttcagtt gttactggac tagtagaagt
     3661 agttggctca cttgaacgat cttgtccagt ttgtggtgct ggatcggctg ggcttgtagc
     3721 aggtttttct tctgttttct ctagggaagc gtttgcattt ctaggtgaag aaatatcact
     3781 ttcgttctta ccagagccag ctgctgtatc agtaagaggt tgagcaaggg tggttgtatt
     3841 tctgttgttg ggttcgttag tggttggtgt actttcgtcg gatgagatag ttggtgtagc
     3901 catggcaagc aagacaaggc ttgcgccgat aaggacagaa ccagttccat ttttgaggga
     3961 acggatgctg tagaccattt ttttctcagt gtgagatggt gtttttctca taatgattct
     4021 ccaatcaata aatttctata tcagtatagc atgtagtaaa acaatatgca agcgttttct
     4081 ttgatttgtg aaaaaaattc ctacttttga gaagttttct gtactatttt atatatcagt
     4141 ataaatgacg gagataaaaa tgtcacataa gccaagccgt attattagga agatgatgtg
     4201 ttcccagcta tttttattca gaaattgatc tctaacatta ccaataaaaa tgaaaaatat
     4261 cttgacaagc aagggaaaat tttgttacaa taatagacgg tactttttac ttttggtctc
     4321 tcaagagtgt acagggacgt gctgacaaat gttgcaaaag tacacacaga tgatatctgt
     4381 caccaagtgt atcatcacca aaaataaaaa aacacaggag aatgtagatg cctacaatta
     4441 accaattggt tcgcaaaccg cgtaaatcaa aagtagaaaa atctaaatca ccagctttga
     4501 acgttggtta caatagtcat aaaaaagttc aaacaaacgt ttcttcacca caaaaacgtg
     4561 gtgttgcaac tcgtgttgga acaatgacac ctaaaaaacc taactcagcc cttcgtaaat
     4621 tcgctcgtgt acgtttgagc aaccttatcg aagttactgc ctacatccca ggtatcggac
     4681 acaacttgca agagcacagc gtggtgcttc ttcgcggtgg acgtgtaaaa gaccttccag
     4741 gggtacgtta ccatatcgtc cgtggtgcac ttgatactgc aggtgttaac gatcgtaaac
     4801 aaggccgttc taaatacggt actaaacgtc caaaagcata aggaaagggg ataaagagaa
     4861 atgagtcgta aaaatagagc tccaaaacgt gacgtattgc cagatccgct atacaattca
     4921 caactagtta ctcgtcttat caaccgcgtt atgcttgatg gtaaacgtgg tactgctgct
     4981 tcaatcgttt acggtgcttt tgagcaaatc aaagaagcta ctggcaacga tgcacttgaa
     5041 gtatttgaaa cagctatgga aaacatcatg cctgtacttg aagtacgtgc acgtcgtgtt
     5101 ggtggttcta actaccaagt cccagttgaa gttcgtccag aacgtcgtac aacacttgga
     5161 cttcgttggt tggtaacaat cgctcgtctt cgtggtgaac acacaatgca agaccgtctt
     5221 gcaaaagaaa tcttggatgc tgctaacaac actggtgcag cagttaagaa acgtgaagat
     5281 actcaccgta tggctgaagc taaccgtgca ttcgcacact tccgttggta agataggatg
     5341 cgaaagcgtt aagaaagtcc cagagaaaat agggaatcga agcaggttgc ggttgcaacc
     5401 aatgagattc atctttttct ccagactttt agcttgagct caactaaatc atgatgctag
     5461 gcacggtaag gatgcaaggt gaaaatagga aactgacgca gtattcaacg aatacaagga
     5521 gttttatctt tttcacgcag catcccgttc cagctcacat cggctaacta actttagcct
     5581 gggttcaaat tagctaaatc gattagtatt agctataact cagcttacca tctcgtaagt
     5641 tgaaaccaac aatagcatga aaacattgag aacgggtagg tcctgcctat ccgtttttat
     5701 taaaatcgtg ttataataga atagaaatca aaaataaata ggagaaacaa acctcatggc
     5761 acgcgaattt tcacttgaaa aaactcgtaa tatcggtatc atggctcacg tcgatgccgg
     5821 taaaacaaca actactgagc gtattcttta ctacactggt aaaatccaca aaatcggtga
     5881 aactcacgaa ggtgcgtcac aaatggactg gatggagcaa gagcaagaac gtggtatcac
     5941 gatcacatct gctgcgacaa cagctcaatg gaacaaccac cgcgtaaaca tcatcgacac
     6001 accaggacac gtggacttca caatcgaagt acaacgttct cttcgtgtat tggatggtgc
     6061 ggttaccgtt cttgactcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca
     6121 agcaactgag tacggagttc cacgtatcgt atttgccaac aaaatggaca aaatcggtgc
     6181 tgacttcctt tactctgtaa gcacacttca cgatcgtctt caagcaaatg cacacccaat
     6241 ccaattgcca atcggttctg aagatgactt ccgtggtatc attgacttga tcaagatgaa
     6301 agctgaaatc tatactaacg accttggtac ggatatcctt gaagaagaca tcccagctga
     6361 ataccttgac caagctcaag aataccgtga aaaattgatt gaagcagttg ctgaaactga
     6421 cgaagaattg atgatgaaat acctcgaagg tgaagaaatc actaacgaag aattgaaagc
     6481 tggtatccgt aaagcgacta tcaacgttga attcttccca gtattgtgtg gttcagcctt
     6541 caaaaacaaa ggtgttcaat tgatgcttga tgcggttatc gactaccttc caagtccact
     6601 tgacatccca gcaatcaaag gtattaaccc agatacagac gctgaagaaa ctcgtccagc
     6661 atctgacgaa gagccatttg cagctcttgc cttcaagatc atgactgacc cattcgtagg
     6721 tcgtttgaca ttcttccgtg tttactcagg tgttcttcaa tcaggttcat acgtattgaa
     6781 tacttctaaa ggtaaacgtg aacgtatcgg acgtatcctt caaatgcacg ctaacagccg
     6841 tcaagaaatc gacactgttt actcaggtga tatcgctgct gccgttggtt tgaaagatac
     6901 tacaactggt gactcattga cagatgaaaa atctaaaatc atccttgagt caatcaacgt
     6961 tccagaacca gttatccaat tgatggttga gccaaaatct aaagctgacc aagacaagat
     7021 gggtatcgcc cttcaaaaat tggctgaaga agatccaaca ttccgcgttg aaacaaacgt
     7081 tgaaactggt gaaacagtta tctcaggtat gggtgaactt caccttgacg tccttgttga
     7141 tcgtatgcgt cgtgagttca aagttgaagc gaacgtaggt gctcctcaag tatcttaccg
     7201 tgaaacattc cgcgcttcta ctcaagcacg tggattcttc aaacgtcagt ctggtggtaa
     7261 aggtcaattc ggtgatgtgt ggattgaatt tactccaaac gaagaaggta aaggattcga
     7321 attcgaaaac gcaatcgtcg gtggtgtggt tcctcgtgaa tttatcccag cggttgaaaa
     7381 aggtttggta gaatctatgg ctaacggtgt tcttgcaggt tacccaatgg ttgacgttaa
     7441 agctaagctt tatgatggtt catatcacga tgtcgactca tctgaaactg ccttcaagat
     7501 tgcggcttca ctttccctta aagaagctgc taaatcagca caaccagcta tccttgaacc
     7561 aatgatgctt gtaacaatca ctgttccaga agaaaacctt ggtgatgtta tgggtcacgt
     7621 aactgctcgt cgtggacgtg tagatggtat ggaagcacac ggtaacagcc aaatcgttcg
     7681 tgcttacgtt ccacttgctg aaatgttcgg ttacgcaaca gttcttcgtt ctgcatctca
     7741 aggacgtggt acattcatga tggtatttga ccactacgaa gatgtaccta agtcagtaca
     7801 agaagaaatt attaagaaaa ataaaggtga agactaatcc gtcctcactc tagaaggaag
     7861 tcacttagtg gcttcctttt gtctttagaa aata
//
LOCUS       DAVLIK010000069         7837 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLIK010000069 DAVLIK010000000
VERSION     DAVLIK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.069"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(204..500)
                     /locus_tag="VXE87_001895"
     CDS             complement(204..500)
                     /locus_tag="VXE87_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV0843385.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(1043..1936)
                     /locus_tag="VXE87_001896"
     CDS             complement(1043..1936)
                     /locus_tag="VXE87_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0843386.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(2690..2920)
                     /gene="blpU"
                     /locus_tag="VXE87_001897"
     CDS             complement(2690..2920)
                     /gene="blpU"
                     /locus_tag="VXE87_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0843387.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(3123..3413)
                     /locus_tag="VXE87_001898"
                     /pseudo
     CDS             complement(3123..3413)
                     /locus_tag="VXE87_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3459..3692)
                     /locus_tag="VXE87_001899"
     CDS             complement(3459..3692)
                     /locus_tag="VXE87_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0843388.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(3698..4690)
                     /gene="plsX"
                     /locus_tag="VXE87_001900"
     CDS             complement(3698..4690)
                     /gene="plsX"
                     /locus_tag="VXE87_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0843389.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPMRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTIDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(4687..5457)
                     /gene="recO"
                     /locus_tag="VXE87_001901"
     CDS             complement(4687..5457)
                     /gene="recO"
                     /locus_tag="VXE87_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0843390.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQNLTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(5454..6623)
                     /locus_tag="VXE87_001902"
     CDS             complement(5454..6623)
                     /locus_tag="VXE87_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0843391.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            6772..7782
                     /locus_tag="VXE87_001903"
     CDS             6772..7782
                     /locus_tag="VXE87_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV0843392.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
BASE COUNT         2291 a         1818 c         1241 g         2487 t
ORIGIN      
        1 ataggcagtt tcatattata acgattcaaa gtagcgtaat ctactaccaa aaaaagtaaa
       61 aataatttcc cttgaaaagg aagatagctt ttaaaataga ttgacaaact tatgataaca
      121 aaaaacaaaa gggttatccc aataaaatta agataaccta aaatactttc acattctttt
      181 ttagaaagta ttttcatcta gttctaccat agagctgctt tagcagcacc tttctttttc
      241 aatatataaa gaactgttgc tgcaataccc gaaccaatag aacctactcc tgtgattgca
      301 cctacaattg aaattactgc tgtaactgta ctataagcac taatcaaatt gactacagta
      361 gcagcagctt ttgtcgaaat tcctaatgtc ccagccaaca taggaaaaga aacaacacct
      421 aagcttaacc aactaatgac tgctaacatt gctgaaacaa taagaaattt attatgaaat
      481 tccattcttt tagatttcat tttagtgtac tccttttgta tattatgtat gttttattga
      541 gagttaattc gcacatgttg tattcctaac tctcttcaaa tgttcgtcta tattttatac
      601 tacttttatt aacatatcta taataaataa attactacta cattttccta gattatcaaa
      661 ttacttttat atcactaaga ctcaataaaa gataatgtct atttaacttt tatacgatta
      721 ctacctcctt tttagtttac acttcctaca tcataaataa acatactaaa ccctcacaat
      781 ctccaaataa ctcttctata tcattgaaaa ttgagtttca tcctctatac taatgtagga
      841 aacctattaa aacattcctt taatccaata taagaatacc ttgttccatt aatctctacc
      901 cgatattata gatagaacca aattcctata cttaaaagga caaataacgt tccaaccata
      961 ataaacctcc tttctttttg agaacgtttt ctttataggt ttagtgtagc aaaaacatga
     1021 aaaaaacaac atgacttaga agtcaggttg ttgggaaatc tatctgtttt tctgctaaaa
     1081 ttctctgaac taatacctga tcgtctagca attctgctag agaaatcgcc ttttcataga
     1141 aactttctgc ctctaaaata ttcttgtcta caaataaagc atattttgcc tttagcaaaa
     1201 atagatgagg tcggtaaaaa acatgtcttg ttttagcaat aattttctca aatgtttgaa
     1261 tatatatcag actatcttct gtctgaattt ggataaatag gctcagaaga actttttcca
     1321 tttgaactag gctagcctta tcttcatatt ctgaacatag caatactttt tgagctaact
     1381 cctcaaaatg ttctttatct tctaatccca tagcacaaca aaagaaatac aattcaataa
     1441 tcaacaaatc atttacagaa aaatatttct tttttaataa ctgctggaaa tattcttcca
     1501 ctaaccctaa accgtaggtc acatctgaac taccataaat atcaaaacga gcttgtgtca
     1561 catccacaat taactgctct tcctcaggca aattctcata atagttttca tatatttcct
     1621 caagtatagc ttcttttcgt tcgattcttc ccttatcagc gtaggtttga gaatgaatca
     1681 gctcatcttt gagttttagg aatccttttg gaatctctat aaccttaaca tccacaatat
     1741 tctgtaatga tactccaagt ttatccgcaa tcaataataa tttaggaagt gttgctaaag
     1801 cttgcccatt ttcaatacgt gctagctgac gaatcgtcaa ctctgattca tcaccacaaa
     1861 tatctatctg agtttttcca caagatcgcc taatagtttt gattttataa ccaatttcac
     1921 gtttcaactc atccatagta atactcctta agttgattac aaagatttct ttttcttcct
     1981 aattcttttg tcaatcatat ataaaacgat aagcgaaaac agcggtagaa caatataact
     2041 cttttcactc attatcagct gaaatcccag ggttgctagt atcttaaaga tgaaaatatt
     2101 catcaaaaat agaaaaacaa atactaaaaa atattttaaa accttcttca tttcttttct
     2161 tcaactttcc taatttctac acctatttta tcgaaaatat atataaaact ccaaataaac
     2221 acttcgactg cacttttttt ggcaaaaaat agacagaaca aacatcctac ctactaaaaa
     2281 tatgatatga aaggaaaatg attttttact gacaccctag gcaagcttgg gacaaataaa
     2341 tcattgatag caacatttac gacatcctat ttaaagttcc ttcaatttct aatgtccccg
     2401 ctatttctaa gccacctctg gtatgatcta ttcctagtca gaatagataa caccgttcta
     2461 aattacgatt catagttact ccttttttga ctcgttacta taagactcct atttacatgc
     2521 gcaaaataat tttgattcag attcatcatt tatagttttg attatttttt aacagatttt
     2581 tctgttttct tctccgaaga ctttaaaaat ttttttctaa ttaaatcatc catataagga
     2641 ccaaatatac caactactaa accaataata aaacttttaa aatccataat taccaccaac
     2701 atgtcgctgc ataggccaca cctccaagta tagctcctcc cacagcacca gttgctgcac
     2761 cttgccatgt tcttgtttta attcctagct gaagacctcg tgctgctcct cctccaacac
     2821 ctgctttggc aaaatctccc caattgcatc cgccaccttc aacgcaagca agcatctcag
     2881 tatccataat ttcaaattgt gacatcgttt ttgtattcat aacgaatacc tcttttttat
     2941 ttttaatatt tgtcttgtta caaacttgac aagtttagta taacagtatc tattaatttt
     3001 tttcatccaa atcttgaatt ggcatcgaaa cgtcttgaat tagctttttt gtttcaaaat
     3061 catctctatt tttaaaaaag atgttttcta atcacttttt tactattaga cttcctgcaa
     3121 aactagaatc ctagttcatg attgataata ccagcaatca aattcattcg taatccgaag
     3181 cgtttacgat gatttcgata ggttgttgaa aacattttaa acgtttttat tttggcaaag
     3241 atattctcaa ccttgcttct ctccttagat agcgcatgat tacaggcttt atcttcaact
     3301 gttagcggct tgagtttgct ggatttacgt ggagtttgtg cttgaggata tatcttcatg
     3361 agcccttgat aaccactgtc agccaagatt tttccagctt gtccgatatt tctcatttct
     3421 aaaaaccatc tacttccgtt gacttggaac tccgattgct attttccttg aatgatttta
     3481 accacatctc ctacgttttg gagttggtca atttcttcat cgctgatttc gatactaaat
     3541 tcatcttcca gagtcaagat aaactccatc aagtcaacag aatccgcatc caaatcgtct
     3601 ttcagactca aggattctgt cacgacaaag tcctctccct gtcgctcttg gataatggtc
     3661 acaatacggt caaaaatttc tttttctgtc atctctttta ttctcctgaa aattcacgcg
     3721 cagtctgggc aactacgtct gtttctagca tggtacgaat ctggcgaatc gtactataaa
     3781 cagccttggc atcgcttgag ccatgagtct tgacaacagg tgccttaaca ccaaacaaga
     3841 ccgctccacc aacatctgaa taattgagct gttttttcaa accactgagg ctgtccttga
     3901 gaaggagggc acctagtttc gctcgaagac caccacctgt aatagctgtc ttgagcaagc
     3961 ccatgattcc catagctgtc ccttcgatgg atttgagcac agcgtttccc gtgaaaccat
     4021 ctgccacaac aacatctgca acgccattca tcaaatcacg cgcttccacg tttccgataa
     4081 agttcaaact ttcatcagcc gccagtaatt cataagtttc cttacgaagc gggtcgccct
     4141 tgctactctc tgttccgttg ttgagcaaac caacacgtgg ttgcgcaatg ccacgaacat
     4201 tcttggcata gaaagaacct aggacagcgt attgatggag gtgctgggct gtattttctg
     4261 cattagcacc gaggtcaagc atgtcaaaac ctttcccatc tatagtcggc aatgttgaca
     4321 taagtccagg acggtcgata ttcttgatac gacccacgat gaagaatcct gctgccaaca
     4381 aggcacctgt attcccagcc gaaaggacag cgtctgcttc accatctttg acagccttgg
     4441 ctgccaatac catactggca tttttcttat tcctaatagc tctcataggt tcatcatccg
     4501 aatcaatctt ctcatccgta tggataatgc tgacgcgctc tgtcgctgtc agatattgct
     4561 tgattttagc ttcatctccg taaagttgaa cctcgatatc tgaaaagtca gatagggctt
     4621 gattgacacc ctcaacaatg gcctgaggtg cgtaatcgcc ccccatggca tctactgcga
     4681 tttttttcat ttcttttcct cttttagtaa ttgtccccag tctgctaggg aatcaataaa
     4741 tttctttgat tttaggtgaa tcccaacgta ctcttcatat aattgatcca taaattggcg
     4801 tagctcttgc ttgattccag gcttgagcga aatggtctcc aaagtctcaa aatcaatagc
     4861 ttgaaattga ttgagcagat aggggatatt gggattgaga tgacaacgtc tcttatcctc
     4921 atgataatgc tctggacaga ggcaggctcc atatttgaaa gaaaagtcaa aagcctgacc
     4981 aacccgatgg cagaagacac actcattaaa attgaggctg attccaaatc gagtcaaatt
     5041 ttgaatttca aaaatattgg tcaaaacctg ataatccaag cctgcttcca tcaactccaa
     5101 agtcttttgc aaaaaagcaa acaagggagc atcctgctga ttgtcctgca aactagcatc
     5161 tgcaagagct gccacatagg tcgcataggc catgacaaag aggtcactat taatcttggg
     5221 aaaagtcatg acctcatgat agtcttcgat gtaactgagt ccgtcatcat tgattcgcaa
     5281 gagaaatcgt gccagcacca agggctgaat aacaggcgcc agcttagact gaccagcgtg
     5341 tttgacaaaa aacatgcgtt tgccaacctg ctctgtaaaa attttgacga gcttgtcatc
     5401 ctcacgaaaa ttgcgattgt aaagcaccaa gccttgactc gtgatagact gaatcatgct
     5461 tctctcatgt actcctcaag tcgtttcatg gcttctttga tagtctccat gctggctgca
     5521 taagataggc ggacgtagcc ttccccgtaa cgtccaaagg ctgcaccagg gataaaggca
     5581 acggccttct tctgagcaaa atccttcaga aaagcaaagg agtcttgatt gtagcccgct
     5641 ggaattttag caaaaatata gaaggcaccg tctggtttga taatctcaaa accaagagca
     5701 gtcatttttt cgatgatata gtcccgacgt tggatatatt ccttcttcat gggctccgca
     5761 tcgtttttac cagccgtcaa ggcttctacc gcagcatgtt gcgccatggt atttgcggca
     5821 gtgaccaagt actggtgact cttgattaac tgggctgtga aggtcgcagg agcgaaaatc
     5881 agccccaaac gccaacctgt catggcatgc gatttagaca aaccattgat aataatagcc
     5941 tggtctctca acatcgttcc tagagacaca tgggcttcgc ctgtgtaggt caattctgag
     6001 taaacctcat cacagacaac aaaaatttcg tacttgcgta aaacagctgc caaggcctct
     6061 aactgctctc gactgtaggt aattcctgtc ggattggctg gatagttgag aataaccgcc
     6121 ttgagcttat caccctgctc caaaatggcc ttctccaaca tctcaggagt caagacaaaa
     6181 ccattttcag tcgtatcaat ctcaacaatt tctgccccaa ctaagttaac aatcggttca
     6241 tagcctggat aagcaggagc tggcaaaagt accttgtctc cctcttccaa aatagccgtc
     6301 aaagtcgcag ataaagcctc tgtcgctccg atagtgacca agatttcatt ttcaggagca
     6361 tagtccagtt ggtacttttc cttaacaaaa tcactggccg cctgacgtag agtcagcaga
     6421 ccactcatcc ctgtatagta ggattggttc tgatcaatcg ctcgcttggc cgcctccttg
     6481 acatggtctg gcgttgtaaa atcaggttcc cccaaggtca aacgcaagac cccaggaatc
     6541 tccgaaatag cctggtcaaa ctgacgaatc aacgaaactt gaattttatc taactgttta
     6601 ttaaagcgct tagttaagtc catagatacc tcctactttc aaaacgtatc tctattatac
     6661 tacaaaagcc ccccgaccgc aaaaatacat tagagaatag ctttccactt tctattttac
     6721 ttttcctgtt tataggtcta taatggtaat agattttatt tggaggtttt tatgtcattt
     6781 ctatcaaaaa atggagcagg tatcttggcc tgccttctca tttctatcgt atcttggtac
     6841 ttaggaggat tcttccctgt gattggcgcg cccgtttttg ccattttcat aggcatgctc
     6901 ctacatccct ttctctcgtc ctataaacaa ctggatgctg gtttgacctt tagttccaag
     6961 aagttgctcc aatatgccgt tgtcttgctt ggttttggtc tcaatatctc gcaggtcttc
     7021 gcagttggcc aatcttcact ccctgtcatc ctgtccacta tctcaatagc tctgattatt
     7081 gcctacctct tccagcgttt ctttgcactg gatacaaaac tggctacctt ggttggagta
     7141 ggttcttcta tctgtggggg ttctgccatt gcagcgacag cgcccgttat tgatgctaag
     7201 gaaaaggaag tagcccaagc catttccgtt atctttttct tcaatgtctt ggctgcgctc
     7261 atctttccaa ccctcggcac ctggcttcat ctatccaatg aaggcttcgc cctctttgca
     7321 gggactgcgg tcaacgacac ttcctctgta acggctgccg ccagcgcttg ggacagtctt
     7381 taccaaagca ataccctcga gtctgcaacc attgttaaac tcacacgtac tttggccatt
     7441 atccctatca cgctctttct atcctactgg caaagtcgcc aacaagaaaa caagcaaagc
     7501 ctacaactga aaaaagtctt cccacttttt atcctttact ttatccttgc atcgctccta
     7561 accacccttc tgacctctct cggtgtgtct agtagtttct ttacccctct caaacaactc
     7621 tctaaattcc tcattgtcat ggccatgagt gctatcggtc tcaaaaccaa tctggtcgct
     7681 atggtcaaat ccagtggaaa atccattctt cttggagcca tctgctggat tgccatcatc
     7741 ctcaccactc ttggtatgca gacccttatc ggcattttct aatactcttc gaaaatctct
     7801 tcaaaccacg tcaacgtcgc cttgccgtat atatgtt
//
LOCUS       DAVLIK010000070         7668 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLIK010000070 DAVLIK010000000
VERSION     DAVLIK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7668
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.070"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..2223
                     /locus_tag="VXE87_001904"
     CDS             <1..2223
                     /locus_tag="VXE87_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV0843393.1"
                     /translation="LLHDYSNIVDNVLTDLNSVQYDSNAIKKILDISDKVKNTELYLD
                     EQFVKTKANIKDTLSKLLSADAAIAENSNSIIDNYVIQKIKQNKEALLLGLTYLERWY
                     NFKYGETKAKDLVMYHLDFFGKSNSSALDNVIQLGKSGFNNLLAKNNVITYNVLLSKN
                     YGTESLFKALEGYRKVFLPTTSNNEWFKAQTKAYIVEEKSSIPEVSKKQSEQGTKYSI
                     GIYDRLTSPSWKYQSMVLPLLTLPEEKTVFMIANISTIGFGAYDRYRSKVHPKGDNLN
                     KFVEDNVREAAKRFRDHYDYWYKILEPENREKLYRSLLVYDAFKFGRDNTEDKVTYQA
                     DFETDHPAIKYFFGPAGNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNS
                     DREIYLGGYGRRSGLGPEFYAKGLLQAPDHPYDPTITINSVLKYDDSENSTRLQVADP
                     TQRFNSAEDLHNYMHNMFDLIYTLEILEGRAVAKLDYNAKNDLLRKIENKYKQDPDGN
                     SVYATNVVRRLTMDEVNKLNSFDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSA
                     LSGEKGTPGDLMGRRIAFELLAAKGYKEGMVPYISNQYEKDAKAAGSKIKSYGKEVGL
                     VTDKLVLEKVFNNRYSSWVEFKKAMYNERIAKFNNLISVSFNNPNVSWGRTNRITITS
                     IANLQNMINTAVNEDAEDFRAQLYPDTNSRVLKLKKAIYKAYLDQTNDFRRSIFENKK
                     "
     gene            2267..>7668
                     /locus_tag="VXE87_001905"
     CDS             2267..>7668
                     /locus_tag="VXE87_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0843394.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSIFLGSFLFALSVVGVSTYHYLDYS
                     TLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDR
                     TVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKG
                     EPEVQPVLPEAVVAEKGEPEVQPVLPEAVVTEKGEPEVQPALPEAVVTEKGEPEVHEK
                     PDYTQPIGANLVESEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEPISTVSEV
                     ASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVGEDGERQIVTSYEELHG
                     KKISESVETVTILKEMKPEIIVKGTKERPKEKTAPVLTLTKVTEDAMNRSANLNYELD
                     NKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDLFKDYKIATTMIYDRGQGS
                     ETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMYLKI
                     TSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKPHPK
                     EDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEGKHY
                     TIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVTGNV
                     LGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYVDAN
                     LIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLSHHG
                     YIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKEHHR
                     IKPISQSEADTKIMMLGITAQDFAVNEPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYR
                     NIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYA
                     DGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASVQLI
                     SPEVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADHQLN
                     SDEAAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLL
                     DFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDWFIH
                     AAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYNTMA
                     YSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRVPTP
                     VWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNPNNN
                     DQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSI
                     GHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHVEAD
                     AVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSSIND
                     LIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAF
                     RMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYH
                     DVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVFKAL
                     LKNTDGFFNPLFKKDI"
BASE COUNT         2804 a         1113 c         1543 g         2208 t
ORIGIN      
        1 ctattgcatg actacagtaa tattgtagat aatgttttaa ctgacttgaa ttctgtacaa
       61 tatgattcaa atgcaattaa gaaaatatta gatatctcag ataaagttaa aaatacggaa
      121 ttatacttag atgagcaatt tgttaaaaca aaagcaaata taaaagatac tttatcaaaa
      181 cttctgtcag cggatgcagc aatcgctgag aatagtaatt cgataattga taattatgtt
      241 attcagaaaa tcaaacagaa taaagaagct ttattgttag gattaacata cttagagcgt
      301 tggtacaatt ttaaatatgg tgaaacgaaa gcaaaagatt tagttatgta tcacttggat
      361 ttcttcggta aatctaatag ttctgcatta gataatgtta ttcaattagg taaatctgga
      421 tttaacaatt tactagcaaa aaataatgta attacttaca atgtattatt atctaaaaat
      481 tatggaactg aaagtttatt taaagcatta gaaggatata gaaaagtatt cttaccaaca
      541 acttctaaca atgagtggtt taaagctcaa actaaagcat atattgttga agaaaaatct
      601 tctattccag aagtaagtaa aaaacaatca gaacaaggaa ctaagtattc tataggaatt
      661 tatgatagat taactagtcc gtcatggaaa tatcaaagta tggtcttacc actattaact
      721 ttacctgaag aaaaaacagt atttatgata gcgaatattt caacaatagg atttggtgct
      781 tatgatagat atagaagtaa agtccatcct aaaggagata acttaaataa atttgtagaa
      841 gacaatgtaa gagaagctgc aaaaagattt agagatcatt atgattattg gtataaaata
      901 ttagagcctg agaatagaga gaaactttat agaagtttat tagtatacga tgcatttaaa
      961 tttggtcgag ataatactga agataaagta acttatcaag ctgattttga aactgatcat
     1021 ccagctataa aatacttctt tggacctgcg gggaataatg ttgttcataa tggacacgga
     1081 gcatatgcta ccggagatgc attctattat atggcatatc gtatgttgga taaagatgga
     1141 gctgtaacat atactcatga aatgacacat aactctgata gagaaattta tcttggagga
     1201 tatggaagaa gaagcggatt agggcctgag ttttatgcta agggcttatt acaagcacct
     1261 gaccacccat atgatccaac aataacaatt aactctgtgt tgaaatatga tgattcagaa
     1321 aattcaacaa gacttcaagt agctgatcca actcaacgat ttaatagtgc agaagaccta
     1381 cataattata tgcataatat gtttgattta atatatactc ttgaaatatt agaaggtcgt
     1441 gctgtagcta aattagatta taatgcgaaa aatgatttat taagaaaaat tgagaataaa
     1501 tataagcaag atccagatgg taattctgtt tatgcgacaa atgttgttcg cagattaacg
     1561 atggatgaag ttaataaatt aaattctttt gatagtttaa ttgaaaatga tattattact
     1621 agcagagggt acaaagacca agaatataag agaaatggtt attatacaat tgatttattt
     1681 tcaccgattt attcagctct tagtggagag aaagggactc ctggtgattt aatgggacgt
     1741 cgtatagcat tcgaattatt agctgcaaaa ggatataaag agggcatggt accttatatc
     1801 tcaaatcaat atgaaaaaga tgcaaaagct gcgggaagta agattaaatc ttatggtaaa
     1861 gaagtaggtt tagttacaga taaattagta cttgaaaagg tatttaataa tcgttactca
     1921 tcttgggtag aatttaaaaa agcaatgtat aatgagcgaa tagctaaatt taataatcta
     1981 ataagtgtta gctttaataa tccaaatgta agttggggaa gaactaatag aataacaata
     2041 actagcatag ccaaccttca aaatatgata aatacggctg tcaatgaaga tgctgaagat
     2101 tttagagcac aattataccc tgatacaaat agtagagttc ttaaactgaa aaaagcaata
     2161 tataaagcct atcttgacca aacaaatgat tttagaagat caatttttga gaataaaaaa
     2221 tagtgtttac tattaggaaa taaaaagtga atgtggagga ttagaattgt cattattaaa
     2281 aaaagataaa ttttccatta ggaaaataaa gggtattgtt ggttcgatat tcttggggag
     2341 ttttttattt gcactgtcag ttgttggtgt atcgacttat cattacttag attatagtac
     2401 tttgacacaa actgaacgtg atcaactcaa acaaggtaga cctgatgaat caaaagagtc
     2461 atatgctttg gtttatgaaa aagacgcatt accaaacaca ggaagttctc aatctattat
     2521 gactgtattg ggtttgttag ctatcgggag tcttattgtg attatcacaa aagataaaaa
     2581 gaggaaaaaa atagctacat ttttgattgt aggggcgaca ggtttagtta cactatcaac
     2641 tgcttcagca cttaatttga atgctaacat ccatgagtct ggacgtgatg gtgtgttgca
     2701 aatttctggt tacagatatg ttggttactt ggagcttgat gatagaactg tttcgtcggt
     2761 ttctccagca tcaactgttt ctccagttga gcaacccaaa gttgtgactg acaaaggcga
     2821 accagaagtt cagccagcgt taccagaagc agttgtaact ggaaaaggga aaactgaagt
     2881 acaaccgaca ttaccagaag ctgttgtgac tgaaaaaggg gaaccggaag tacaaccagt
     2941 gttaccagaa gctgttgtgg ctgaaaaagg ggaaccggaa gtacaaccag tgttaccaga
     3001 agctgttgtg actgaaaaag gggaaccaga agtacaacca gccttacccg aagcagttgt
     3061 aactgaaaaa ggcgaaccag aagttcatga gaagcctgac tatacgcaac caataggtgc
     3121 aaaccttgtt gagtctgaag ttcatgagaa actagcatac actgaacctg taggtacaac
     3181 aggagtagat gaaaatggaa acttgattga gccacctgtt aacgatattc cagagtatac
     3241 tgaaccaata tctacagttt cagaagttgc atcagaaaga gaagagttgc cttctttaca
     3301 taccgatatt cgtacagaga ctattcctaa aaccactata gaagaatctg atcctagcaa
     3361 atttataggc gataattctg ttaaacaagt tggtgaggat ggcgaacgtc aaattgttac
     3421 tagctatgaa gagttacatg gcaaaaaaat cagcgagtca gttgaaacag taacaatttt
     3481 gaaagaaatg aagcctgaaa ttattgtaaa aggtacaaaa gaaagaccaa aagaaaaaac
     3541 ggctcctgtt ttaaccttga ccaaagtaac agaagatgct atgaatcgtt ctgccaactt
     3601 aaattatgag cttgataata aagataatgc tgaaatatca agtattgtag ctgaaattaa
     3661 agatggtgat acagtagtta aaagggttga tttatctaaa gaaaaattaa ctgacgctgt
     3721 acaaaatttg gatttgttta aagattataa gattgcaaca acaatgattt atgatcgtgg
     3781 tcaaggttct gaaacgtcta aactggatga aagacctctg cgtttggagt tgaaaaaggt
     3841 cgaaattaaa aatatcgcat ctactaattt agtgaaggta aatgatgatg gtactgaaac
     3901 acctagtgat tttatgaatg aaaaaccttc agaagaagat gttaaaaaaa tgtacttaaa
     3961 aatcactagt cgcgataata aggtaactcg tttaactgta gactctattg aagaagtgac
     4021 tgaagaaggt caaaaacttt acaaaataac tgctgaagca caagatttga ttcaacacac
     4081 agacccaacg aaggttcgta ataagtatgt ttattatata gaaaaacccc atcctaaaga
     4141 agataatgtc tactataact ttaaagattt agtagatgct atgaatactg ataaaaatgg
     4201 tacatttaaa cttggtgcag atttgaatgc cactggtgtt ccaacaccta agaaatggta
     4261 tgttgacggc gactttagag gtacattgaa gagtgtagag gggaaacatt atactatcca
     4321 caacacggag cgtccgttat tccagaatat tattggtggt acagtaacca aagtaaatct
     4381 gggaaatgta aatatcaata tgccatgggc agaccgcatc gcaccgattg ctgacactat
     4441 taaaggtggc gctaaaattg aagatgtcaa agtgactggt aacgtattag gtagaaactg
     4501 ggtatctgga tttattgata agattgacaa ccaaggtaca ctcagaaatg tagcctttat
     4561 cggaaatgtg acatctgtag gtgatggtgg tcaattcttg accggtatcg ttggtgagaa
     4621 ctggaaagga ctagtcgaac gtgcgtatgt tgacgcaaat cttattggca agaaagccaa
     4681 ggctgctggt attgcttatt ggacacaaaa cagtggtgac aatcataaag ttggtgtcga
     4741 aggtgcagtc aagaaaggaa ttgtgaaggg taccattcag gtagaaagtc ctgttgaagt
     4801 cggcggtgct gttggacgtt tgagtcatca tggttatatc ggggaagtcg tatctatgat
     4861 gaaagttaag aagggtgaaa ttttttatgg ttctagtgat atgaatgatg acccatattg
     4921 ggtggcgaat aatgtacgag gaaattatgt agttaatggt gtgagtgaag gtacgatatc
     4981 ttatgctcgt gctaaagaac accatcgtat caaaccaatt tcacagtcag aagcagatac
     5041 taaaattatg atgttaggta ttacagcaca agattttgct gtcaacgaac ctgtggtcaa
     5101 tcgcttaaac cgtttaacca gaaaagaaga tgaatataag tcaacccaag actataaagt
     5161 agatcgagat ctggcttatc gtaatattga gaaacttcaa ccattttata acaaagaatg
     5221 gattgtcaac caaggtaaca aacttgcaga agattcaaac ttagctaaga aagaagtcct
     5281 ttctgttacg ggtatgaagg atggacagtt tgtaactgac ttatcagata ttgataagat
     5341 tatggttcac tatgctgatg gtactaaaga agaaatggac gtcactaaga atgctgattc
     5401 taaagtgaaa caagttcgtg aatataccat cgctggacaa aacgttgttt atacaccaaa
     5461 tatggttgag aaagaccgta accaattgat tcaagatatc aaagataagt tggcgtcagt
     5521 tcaattgatt tctcctgaag tacgtgcttt gatggatgca cgtaagaaac cagaagaaaa
     5581 tactgatgaa cgtaagaatg gttatattaa agacctttac ttagaagaaa gctttgctga
     5641 aacgaaagct aatcttgata aattggttaa atccttagtt gaaaatgcag atcatcaatt
     5701 aaatagtgac gaagcggcta tgaaagcact tgttaagaag gtggatgaaa ataaagctaa
     5761 aatcatgatg gctctgactt atctcaatcg ttactatgat atcaagtatg gggatatgac
     5821 tatcaagaac ttgatgatgt ttaaacctga tttctatggt aaatcagttg accttcttga
     5881 tttcttgatt cgaattggat caagtgagag aaatatcaaa ggtgacagaa ctttggatgc
     5941 ttatcgtgat atgattggtg gaactattgg taagtctgaa ttacatggat tcttagatta
     6001 caatatgcgt ctcttcacta acgatactga tttaaatgat tggttcatcc atgcagctaa
     6061 gaatgtatat gtatcagaac ctcaaacaac gaacccagat tttgttaata aacgacatcg
     6121 tgcatttgat ggtttgaaca acggtgttca taatcgtatg attctacctc tattaactct
     6181 taagaatgca catatgttct tgatttcaac ttacaataca atggcttata gttcttttga
     6241 gaaatatggt aagtatacag aagaagctag aaatgaattc aaaaaagaaa ttgataaggt
     6301 tgcacatgct caacaaacat acttagactt ctggtcacgt ttagcattgc caagcgtacg
     6361 tgaccaatta ctcaagagtg agaatagggt accaactcct gtgtgggata accaaaacta
     6421 tagtggtatt aaaggaataa accgtatggg ttatgatgag aagaaagtac caattgcgcc
     6481 aattcgtgag ttatatggtc caacttggaa attccataat accaactgga atatgggagc
     6541 tatggcatct attttcccaa atcctaataa caatgaccaa gtttatttca tgggaacaaa
     6601 tatgattagt ccgtttggta tttcagcctt tactcatgaa actacacacg ttaatgatag
     6661 aatgctttac ttcggtggtc atagacaccg tcaaggtaca gacgtcgaag cctatgctca
     6721 aggtatgcta caaactccgt caagtattgg tcaccaaggt gaatatggtg ctttaggttt
     6781 gaacatggct tatcatcgtg aaaatgatgg tgaccaatgg tataactatg accctgataa
     6841 gcttcaaact cgtgaagata tcgatcgata tatgaaaaac tataatgaag cactgatgat
     6901 gctagatcat gtagaagcag acgccgtact tccacaattg aatggtgata atagcaagtg
     6961 gttcaagaaa attgatagag aaatgcgcag aaatcttggg gatggtttga ataacttagt
     7021 agcaccgcac caatgggaca acgttcgtga cttaaatcaa gaagagagtt ctaagaaatt
     7081 atcaagtatt aacgatttga ttgataataa tttcatgacc aaacacggaa atccaggtaa
     7141 cggacgttat agaccagagg attttagacc aaactcagct tacgtaaatg tcaatatgat
     7201 ggcaggaatt tacggtggga atacgagtca aggtgctcct ggttcattat cgttcaaaca
     7261 taatgccttc cgtatgtggg gttattatgg atatgacaaa ggtttcacta gttatgtatc
     7321 tagcaaatat caaggtgaag ctgataaaca aaaccagggt agattaggtg atgatttcat
     7381 tatcaaaaaa gtttcaaaca accaattctc aaatcttgaa gattggaaga aatattggta
     7441 tcatgatgtg aaatccagag ctgaaaaagg attcacagag attacaattg atggacaaac
     7501 cattcacaac tataatgaac tgaaagactt attcgacaaa gctgtcacag aagacctcaa
     7561 gaaagctgga aactactcaa atactgagaa tttgaaatcc aaagtcttca aagctcttct
     7621 taaaaacaca gacggtttct ttaatccatt gttcaaaaaa gacattta
//
LOCUS       DAVLIK010000071         7328 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLIK010000071 DAVLIK010000000
VERSION     DAVLIK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.071"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..1382)
                     /locus_tag="VXE87_001906"
     CDS             complement(<1..1382)
                     /locus_tag="VXE87_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEV0843395.1"
                     /translation="MTNFVKFRKNNLTRRKGILSFVVAFTLLLTYLLTASRPVFAGGF
                     PNDAKGISGNGKYYSLGQIEKLYSNQSATYNNLTVITSDTHVNSDDFAFCLANGKKFP
                     SFTDKKPKGSYTLVRDIDKDQYTKLLKDNHRWSAIPDLNKAWDTFSRLSYMYLKDPTD
                     IVKRAWGTDLKTARTYFHQVIQYEIWRYTDGMRVSSDTNIYEYRALSPQQKAALEMIR
                     ADLYKFTVPYENLEYRFYKPDWVFGLGYQALATVRWKIEPATITVTKKWENVKEGAKK
                     PDVWIQLLKDGKPEGERKRIESDKGQTTFEIPNKDEINKYSVKEVDKEGRDWKHKDFT
                     AGQPVNKGNGHFEITNTKKEKPKIKVTFKKIAGDTNKDLAGAHLVLKKIFDDGNGLLI
                     KQWDTIGQPVDIDLDAGSYTLTEEKAPDGYMLAAPVSFYVEEDGQIILPKGEDLEAQN
                     DKTITMVDEK"
     gene            1480..1647
                     /locus_tag="VXE87_001907"
                     /pseudo
     CDS             1480..1647
                     /locus_tag="VXE87_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1627..2156)
                     /locus_tag="VXE87_001908"
                     /pseudo
     CDS             complement(1627..2156)
                     /locus_tag="VXE87_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833457.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
     gene            complement(2140..3603)
                     /locus_tag="VXE87_001909"
     CDS             complement(2140..3603)
                     /locus_tag="VXE87_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEV0843396.1"
                     /translation="MSNKISKNLAYNIGYQLIGIAFPLITSPYLSRILGAENLGIHSF
                     TISVALYFMMFMLLGIANYGNRTIATVKREGKEILSKTFWNIYYVQLLMSVLVTIAYL
                     IYLYFWVSSYKFIAILQLFLLLSNAVDITWLFYGLEDFKQIVFRNTLVKLLGLFLIFS
                     FVHESSDLWKYTLINGGVTLVGQLLLWGQLKGRLSWVKIQKKDLLSHIKPILVLFIPV
                     LAISIFSNMDKYMLGLMVGVKQVGFYDNANRIIDIPKALIAALEAVMLPRTSYLLAEG
                     QEEKSNYYIEVTILYAMMISSVLIFGIISVSDIFSLVFWGEEFLESGRLIAAMAPVFV
                     FSVPGNIIRTQYLIPRAKDKDYVLSLIIGALVNILLNCFLIKPFGAMGATISTVLAEF
                     VLYGVQFWTVRRDLDFKKYLKNGFIFYLFGMIMYLAIIAVKAHLQYNIINLVLLIVLG
                     GIVYTGFCCFYILISRNVHFEILREKIKRKIGYENIL"
     gene            complement(3596..4515)
                     /locus_tag="VXE87_001910"
                     /pseudo
     CDS             complement(3596..4515)
                     /locus_tag="VXE87_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729798.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
     gene            complement(4532..5488)
                     /locus_tag="VXE87_001911"
     CDS             complement(4532..5488)
                     /locus_tag="VXE87_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0843397.1"
                     /translation="MEDLVSIVVPVYNVEKYLKKSIESILNQTYDNLEVLLVDDGSTD
                     SSGEICDSFIKVDSRIRVFHKENGGLSDARNFGIEHMKGQYVSFIDGDDYISKDYVWK
                     LYHSLKNNNSEVSICSFSLVDETGEKIKDELLDSGEVSLSGQQILEKALTADGYRYVV
                     AWNKLYRSTLFEKLKFKKGMLYEDEFLNYPLFWDCKRVSIVEEPLYLYVQRKGSIIQS
                     NMTLEKIKMKDKMHTSRIEFYAEKKNSFLHQRSCQQYCNWIVTITVSHYNVLNVAFLK
                     YLQHQFRRIVKYTQNDDKKLIIQNILGYINIRLAAYVKSKVM"
     gene            complement(5503..6522)
                     /locus_tag="VXE87_001912"
     CDS             complement(5503..6522)
                     /locus_tag="VXE87_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0843398.1"
                     /translation="MIEVSIIIPIYNAEKTIKNCVDSALKQNLESLEVILVNDGSNDS
                     TSKILEQYGDNPQVMIFHQVNMGVSAARNVGLSYASGEYVFFLDSDDILDEGMLSKMY
                     QFAKSNKIDLLSCWHKEPSTTQYGGNDNSSASFIARTKEEIGNHFVDIFPRSACAKLF
                     LRRRIEENNIAFSTEMSLGEDMSFVCQYLMVSRSIAVIDGLYYTIQNVNPQSLSKRYV
                     SNIENSLLMQNQLWDQLLEVYPKIEENYYKQHMDFRFYLASLYVNNLFKFDSPYSSKE
                     KWDNIAQQLKKYRPFLDEKVSKEKKPKNMNEMVIFYLLKSKIPALIYSFYSFKEWWKK
                     KRLKN"
     gene            complement(6519..>7328)
                     /locus_tag="VXE87_001913"
     CDS             complement(6519..>7328)
                     /locus_tag="VXE87_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0843399.1"
                     /translation="TILVVFVGLFYIQRGSNVILFGRSLLDWDGFTLATSYGVRYTGF
                     LEYATLNGQLILFLLPLIRLFRFRFFTQTIIFAFLLEVLVLSKSRIAIVAMLIYIAFA
                     VVNEINSNNKWLIGIFCPIIPFMLFYNFEKIKQIFFQMFSSRSGSNATRFRVYEESLK
                     AINGMEMLLGAGVRIPSTVDILLGSHSMYISFIYRTGVLGSIIITVMFYYLFSKFLKC
                     DSSERLRSIGYILALSVFWLFEELDPHYWCLILFFSTISIFINNRKEEIVG"
BASE COUNT         2489 a         1377 c          918 g         2544 t
ORIGIN      
        1 atcttttcat ccaccatcgt gatggtctta tcattctgag cttctaaatc ctcacctttt
       61 ggtaggataa tttgtccatc ttcttccaca tagaaagata cgggtgcagc tagcatgtag
      121 ccatctggtg ctttttcttc tgttaatgta taggagcctg catccaggtc gatatcaaca
      181 ggctgtccaa ttgtatccca ttgttttatc agcaaaccat taccatcatc aaagattttc
      241 tttaagacaa gatgtgcgcc tgccaaatct ttatttgtgt cgcctgcaat ctttttaaat
      301 gtaactttta ttttaggttt ctctttttta gtattggtaa tttcaaagtg accatttcct
      361 ttgtttacag gttgacctgc tgtaaagtct ttatgtttcc aatcgcgacc ttctttatca
      421 acttctttta cagaatattt gttaatctca tccttatttg gaatttcaaa tgtagtctga
      481 cccttatctg actctatacg ttttcgttcc ccttcaggtt tgccatcttt gagcaattga
      541 atccaaacgt caggcttttt agctccttct tttacatttt cccatttttt agtaacagta
      601 atggtagctg gttcaatttt ccatctaact gttgctaaag cttgatatcc taaaccaaat
      661 acccaatctg gcttataaaa tctatattca agattttcat atgggactgt aaatttatat
      721 aagtcagcac gaatcatttc taaagcagct ttttgttggg gagaaagcgc tctgtattca
      781 tagatgtttg tatcactaga tactctcata ccatccgtat atctccatat ttcgtactgt
      841 ataacctgat gaaaataagt tcgagctgtt tttaaatcgg ttccccaggc tcttttaaca
      901 atatcagtag gatctttcaa atacatataa gataatcttg agaaagtatc ccatgcttta
      961 ttaagatctg gaattgctga ccatctatgg ttatctttta gtaacttagt atactggtcc
     1021 ttatcaatat ctctaaccaa ggtgtagctt cctttaggtt tcttatcagt aaatgatgga
     1081 aacttttttc cattcgctaa acaaaaggca aaatcatcag agttcacgtg tgtatcagat
     1141 gtaatcaccg tcaaattatt atacgttgcg gattgattag aatataattt ttcaatttgt
     1201 cctaaagaat aatatttacc gttccctgat attccttttg catcattcgg aaatccccct
     1261 gcaaatacgg gtcgcgacgc agtaagtaag taagtaagta agagcgtaaa cgctacaaca
     1321 aagctcaata ttcctttgcg tctagttaaa ttgttttttc taaatttaac aaaatttgtc
     1381 attatagatt ttttcacttt ttagttcccg cctttttctt attttgtatc aattttaaca
     1441 attatttttc tccttatgtt ctagttaatt ctttctgtaa actccaaaaa gattatcaac
     1501 gcccttcaac tacactattc taacgccaaa ctggaagcga ccaataatct catcaaacgg
     1561 atcaagcgca atgcctttgg ttttcgaaac tttgaaaact tcaaaaaacg gatttttatc
     1621 gctctgatat tctttaaaat ctggtagata cagaaagact actcgattta ataacaaaaa
     1681 atctatgggt gctgacgaat agtctgaaat cataatatca gccacaaaca ttaaatcctg
     1741 cggattagga taatctgtca cattaattaa tcttttatca gtattattaa aaaatgtatt
     1801 atctacattt ggatgaaaac gaatcaatac tttaactttt ctgttataat gttgtcaatc
     1861 catacctttg cggtgctcca ttcaaaaaaa gctccccaac ttccatacca tacttttcta
     1921 actccttttg gaacaaaagt actcatattt tccactaccc aaactaaatc aagattctca
     1981 tcttgtttta atagttcatc agcaatatac tttggattgt ctccatatcc tctaccacca
     2041 aagttatcaa atacaacttt tcttttattt agtggtaacc aatatttatt ggttaccact
     2101 aaataaaagg ggggaaatat taatctcttt aataataatt tataatatat tttcataacc
     2161 aatctttcgt ttaatttttt cccgtaatat ctcaaaatgt acgtttcttg atattaaaat
     2221 gtagaaacaa caaaagccag tatatactat tcctcccagc actataagga gaacaagatt
     2281 tattatatta tattgcaaat gagcttttac tgctataata gctaaataca taatcatacc
     2341 aaataggtaa aatataaaac cattctttaa atatttttta aagtctaaat ctcttctgac
     2401 tgtccaaaat tgcactccat acaagacaaa ttctgccaaa actgtactaa tcgtagcacc
     2461 catggctcca aaaggtttta ttaagaaaca gttcaataat atattaacta gagcacctat
     2521 tattagagac aacacataat ctttatcctt tgctctagga atcaaatact gtgttctaat
     2581 tatatttcct ggaacagaaa aaacaaaaac tggtgccata gcagcaatta atcttcctga
     2641 ttcaaggaat tcttctcccc aaaatacaag cgagaaaata tcagaaaccg atattatacc
     2701 aaatatcaat acactcgaaa tcatcatcgc ataaaggatt gtaacctcta tatagtaatt
     2761 acttttttcc tcctgacctt ctgctaataa ataagatgtt cgtggtaaca taacagcctc
     2821 taatgctgca attaatgctt taggaatatc gataatacga tttgcattat cataaaatcc
     2881 aacttgctta acaccaacca ttaaaccaag catatattta tccatattac taaagatact
     2941 gattgctaac acaggaatga aaagaactaa aattggtttg atatgagata gtaaatcctt
     3001 tttttgaatc ttcacccaag ataatctgcc ttttaattgt ccccataaca aaagttgccc
     3061 aactaaagtc actcctccgt ttattaaggt gtacttccat aaatctgagc tttcatgtac
     3121 aaacgaaaat attaaaaaca aaccaagaag tttaactaat gtatttctaa aaacaatttg
     3181 tttaaaatct tctaatccat aaaataacca agtaatatca actgcattcg ataataacaa
     3241 aaaaagttgt aaaatcgcaa tgaacttgta actcgacacc caaaaatata aataaatgag
     3301 atatgcgata gttactagaa ccgacattag caactggaca tagtagatat tccaaaacgt
     3361 ttttgataaa atctctttcc cttctcgttt aacggtcgct attgtcctat ttccataatt
     3421 tgcaattcca agtagcataa acatcataaa gtaaagtgct actgagatag taaaagaatg
     3481 aatacctaaa ttttcagcgc ctaatatccg tgataaataa ggagaagtta tcaaaggaaa
     3541 ggcaatacca attaattgat atcctatatt gtaggctaaa tttttactga ttttattact
     3601 catttttctc aactttcgaa aatactataa acttataaaa attgttaaca ccgatagaat
     3661 aatctatatg atgatttaat ttatgaaaca ccgatatctg ttttagctgt tcccaccttt
     3721 tttctgaaaa ttgattattt aactcaaaat taaacatatg aggagaatga ttgttaaaag
     3781 taaggacagc agaccattcg attgggtaca gctctgtagc tattgtaaag aatatatgaa
     3841 ataaaaaata attgcataaa ctattttttc tacgccaata ctcccagagt agttttctcg
     3901 catacagcaa tataggatga ttactatatg acgaaattaa ccaacttgat gctacaatgg
     3961 cttgagaatc ttttcttgat aaatccaaag atttatatac aaaaagtggc aactcaagat
     4021 ttgagaaatc tcctcctgta ttcaacactg ttacatctac ccataatcct ccataacgac
     4081 ataagagttc tacccgaagg atatctgaat agtgtgcacg agaaatcgaa ccctttttat
     4141 atttatcagt gatataatct ggtatatcta tatagtcact tatattttct tctgtcagta
     4201 cgataatctc tcttccaaga aaatgagttc tcattgattg aatacatgtt ctaattaact
     4261 ccggagggcg ttcttcgccc tgaaaccaac aaatccaaac tttattcgaa atgttcatat
     4321 catttttctg ttcactttca gtcaacgaaa tatggctaaa ttgtcgcttc atttttctat
     4381 aagcaatatc aatctcttgt tgaaaagcta tattttgatt gctgataata tatatcggaa
     4441 acattctatg aattttactt ttcaatttac taaaaaagag cgattgtcaa tagaagctaa
     4501 aattttttcc agcattattt ctccttacac cctacattac ttttgatttt acataagctg
     4561 ctaaacgaat atttatatag cctaaaatat tctgtataat cagtttctta tcatcgtttt
     4621 gtgtatattt aacaattctt ctaaactgat gttgcaaata ttttaaaaag gctacattca
     4681 aaacattgta atgactaacg gttattgtaa caatccagtt acaatactgt tgacacgaac
     4741 gttggtgtaa aaaggaattc tttttttctg cataaaattc aatacgcgat gtatgcattt
     4801 tatccttcat ctttattttt tctaaagtca tattactttg tataatgctt ccttttcgtt
     4861 gaacgtataa atataacggc tcctctacaa ttgataccct tttacagtcc caaaatagag
     4921 gatagttaag aaattcatcc tcatacaaca ttcctttttt aaattttaat ttttcaaata
     4981 aagttgaccg ataaagctta ttccaagcaa caacatagcg ataaccatct gctgttaacg
     5041 ctttttctaa tatttgttga ccagacaagg atacttcccc agaatctagt agctcatctt
     5101 ttatcttttc acccgtttca tcaaccaatg aaaaagaaca tatagacacc tctgaattat
     5161 tgttttttag agaatgatac aacttccaca cataatcctt agatatataa tcatcgccat
     5221 caataaacga tacatattgg cctttcatat gctctattcc aaaatttcga gcatccgata
     5281 aaccaccgtt ttctttatga aacactctta ttcttgaatc aactttaata aatgaatcgc
     5341 aaatttcccc actactatct gtactgccat catcgactaa tagaacctca aggttatcat
     5401 acgtttgatt caaaatactt tctattgatt tttttaaata tttttctaca ttatagaccg
     5461 gaacgacaat gcttactaaa tcttccataa ctgatttctc cttcaatttt ttaatcgctt
     5521 tttcttccac cattctttaa atgagtaaaa agaatagatt aacgcgggaa ttttagactt
     5581 cagtaaataa aaaatgacca tctcattcat atttttaggc ttcttttctt tgctcacttt
     5641 ctcatctaaa aatggtctat atttttttaa ttgttgtgca atattatccc atttttcttt
     5701 tgaggaatac ggagaatcaa atttaaataa attattcaca tataaactag caagataaaa
     5761 tctaaaatcc atatgttgct tgtagtagtt ctcctcaatt ttaggataaa cttctaataa
     5821 ttgatcccat aactgattct gcattaatag ggagttttcg atattactta catatcgctt
     5881 agataatgac tgtggattaa cattctgaat agtataatac agtccatcaa ttactgcaat
     5941 actccttgag accatcaagt attggcaaac gaatgacata tcttctccta gtgacatttc
     6001 agtcgaaaaa gcaatattgt tttcctcaat tcttctacga agaaataact tagcacaagc
     6061 acttctcgga aaaatatcca caaaatgatt tcctatttcc tcttttgttc gtgcaataaa
     6121 tgaagctgaa ctattatcat taccaccgta ttgtgttgta ctaggctctt tatgccaaca
     6181 agataaaaga tcaattttat tactttttgc aaactgatac attttagata gcataccttc
     6241 atctaatata tcatctgaat ctaaaaagaa cacatactct ccgcttgcat acgataatcc
     6301 tacgtttctg gcagcagata ctcccatgtt cacttgatgg aaaatcatca cttggggatt
     6361 atcaccatac tgttcaagaa tttttgatgt agaatcgtta gacccatcat tcaccaaaat
     6421 cacttcaaga gattctaaat tttgctttaa ggcactatca acacaatttt taatagtttt
     6481 ttcagcattg tatattggaa ttatgattga tacttctatc atccaactat ttcctctttt
     6541 ctattgttta tgaaaatact tattgttgaa aaaaataaaa ttaaacacca ataatgtgga
     6601 tctaactctt caaaaagcca aaatactgac aaagctagaa tatagccaat acttcttagt
     6661 ctctcagatg aatcacattt taaaaattta gaaaacagat aataaaacat tactgttatt
     6721 attatacttc ctaaaactcc tgtcctataa ataaaactta tatacataga atgtgacccc
     6781 aataatatat ctactgtaga gggaattctg acacctgcgc caagtaacat ttccattcca
     6841 ttaatagctt ttagggattc ctcatacact ctaaagcgtg tcgcattgct acccgatcta
     6901 gaactaaaca tttgaaaaaa aatctgttta attttttcaa aattgtaaaa taacataaaa
     6961 ggaataattg gacagaaaat tccaataagc catttattgt ttgaattaat ctcattgact
     7021 actgcaaatg ctatgtatat aagcattgca acaatcgcta ttctagattt gcttagtacc
     7081 aaaacctcta gaagaaaagc aaaaatgata gtttgtgtaa aaaatctaaa tctaaacaat
     7141 ctaattaacg gtaataaaaa aagaattaac tgaccattta aagttgcgta ttctaaaaaa
     7201 cctgtatatc ttacaccata actagtagct aatgtaaatc cgtcccagtc taacaaactt
     7261 cttccaaaca aaattacatt ggagcctctt tgtatataga ataaaccgac aaaaacaact
     7321 aagatagt
//
LOCUS       DAVLIK010000072         7267 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLIK010000072 DAVLIK010000000
VERSION     DAVLIK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.072"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            166..1425
                     /locus_tag="VXE87_001914"
     CDS             166..1425
                     /locus_tag="VXE87_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0843400.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1501..1636
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1675..2175
                     /locus_tag="VXE87_001915"
     CDS             1675..2175
                     /locus_tag="VXE87_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0843401.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2251..2619
                     /gene="rplL"
                     /locus_tag="VXE87_001916"
     CDS             2251..2619
                     /gene="rplL"
                     /locus_tag="VXE87_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0843402.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2806..2979
                     /locus_tag="VXE87_001917"
     CDS             2806..2979
                     /locus_tag="VXE87_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843403.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQS"
     gene            2976..3224
                     /locus_tag="VXE87_001918"
                     /pseudo
     CDS             2976..3224
                     /locus_tag="VXE87_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3238..3561
                     /locus_tag="VXE87_001919"
     CDS             3238..3561
                     /locus_tag="VXE87_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843404.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKQPINFANLLDSLIVSEYQMEPNLW
                     EVSHD"
     gene            3554..3934
                     /locus_tag="VXE87_001920"
     CDS             3554..3934
                     /locus_tag="VXE87_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0843405.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3947..4141
                     /locus_tag="VXE87_001921"
     CDS             3947..4141
                     /locus_tag="VXE87_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0843406.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIV"
     gene            4183..4770
                     /locus_tag="VXE87_001922"
     CDS             4183..4770
                     /locus_tag="VXE87_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0843407.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYCASLIS
                     FLWMYAQRKQAHKVNMKSRIKWIGIGLASLLIISLCFSLIHAQESTNQANLIGLQYQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            4972..5109
                     /locus_tag="VXE87_001923"
                     /pseudo
     CDS             4972..5109
                     /locus_tag="VXE87_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
     gene            5399..6802
                     /locus_tag="VXE87_001924"
     CDS             5399..6802
                     /locus_tag="VXE87_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV0843408.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQKLESALKQYNGP
                     YILSDKRWDEVPIYLRYGVFRPSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYLYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAASGFRSWRETFPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            6991..>7267
                     /locus_tag="VXE87_001925"
     CDS             6991..>7267
                     /locus_tag="VXE87_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0843409.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEY"
BASE COUNT         2410 a         1133 c         1501 g         2223 t
ORIGIN      
        1 tcaaaacatt gttttgaggt tgcagataga actgacgaag tcagctcaaa acactgtttt
       61 gaggttgcag atagaactga cgaagtcagt aaccacacct acggcaaagt gaatctgaag
      121 tggtttgaag agagtacaac ttgtctttta aaaaaggagt ctataatgaa agtctttcag
      181 catgtaaata tcgtgacttg tgatcaaaat ttccatgttt atcttgatgg aatcttagca
      241 gtcaaggatt ctcaaatcgt ctatgtcggt caagataagc cagcgttttt agaacaagct
      301 gagcagatta tagactatca gggagcttgg attatgcctg gtttggtcaa ttgtcacacc
      361 cattctgcaa tgacaggtct gagagggatc cgagatgaca gcaatctcca tgaatggctc
      421 aatgactata tctggccagc agaatctgag tttactcccg acatgactac caatgcggtc
      481 aaagaagccc tgacagagat gctccagtca ggaacaacaa cctttaacga tatgtataat
      541 cccaatggtg tggatatcca gcaaatttat caggtggtga aaacttccaa gatgcgttgt
      601 tatttttctc cgactctctt ttcttcagag acagaaacaa ctgctgagac tataagcaga
      661 actcgatcca tcatagacga aatcttaaaa tataaaaatc caaatttcaa ggttatggta
      721 gcacctcatt ctccgtatag ctgcagtaga gacttgctgg aagcgagttt ggaaatggca
      781 aaagagctaa atattccgct ccatgtccat gtggcggaga ccaaggagga gtcaggaatt
      841 atcctcaaac gatacggcaa acgccccctt gcttttcttg aagaactggg ttatttagat
      901 catccgtccg tatttgctca cggggtcgaa ttaaacgaga gagaaattga acgcttggca
      961 tcttctcaag tggctatcgc ccacaatcct atcagtaacc tcaaactggc atcaggaatt
     1021 gctccaatta tccagctcca aaaagcggga gtagcagtcg gaattgcgac tgactcggtt
     1081 gcttccaata acaatctaga tatgtttgag gaaggaagga ctgcagctct tcttcagaag
     1141 atgaaaagtg gggatgccag ccagtttcca atcgaaacag ctctcaaggt actgacaatc
     1201 gaaggggcta aggtccttgg aatggaaaat cagataggaa gtctggaagt cggcaagcaa
     1261 gcagattttc tggtcattca accacaaggg aaaattcatc tccaacctca ggaaaatatg
     1321 ctgtctcacc tggtttatgc agttaaatct agtgatgtag atgatgttta tatcgccgga
     1381 gaacaggttg ttaagcaagg tcaagtcctg acagtagaac tttaaaagaa aaatcacgaa
     1441 aaattttaaa aaaagtttgc aaaaatcttg cattcttttt ttgactatgc tatacttata
     1501 tacggtttaa aaaaactgcc taagacagta ggggagctcg actcataaat atcctaccga
     1561 ggacaagacg tatcatgtaa aaagaagcgt attgtacttt cgtgtctagg tttgggcgcg
     1621 tttttctttt tgaaaaattc cccaagcaaa ataattacgg aggtgaacac actaatgagt
     1681 gaagcaatta ttgctaaaaa agcggaacta gttgacgtag tagctgaaaa aatgaaagct
     1741 gctgcatcta tcgtcgttgt agacgctcgt ggtttgacag ttgagcaaga tacagttctt
     1801 cgtcgtgagc ttcgtggaag cgaagttgag tataaagtta ttaaaaactc aatcttgcgt
     1861 cgtgcagctg aaaaagctgg tcttgaagat cttgcatctg tatttgttgg accatctgca
     1921 gtagcatttt ctaatgaaga tgttatcgca ccagcgaaaa tcttgaacga cttttctaaa
     1981 aacgctgaag cacttgaaat taaaggtggt gcaatcgaag gcgctgtcgc atctaaagaa
     2041 gagattcttg cacttgcaac tcttccaaac cgcgaaggac ttctttctat gctcctttct
     2101 gtacttcaag cgccagtgcg caacgttgct cttgcagtca aagcggttgc agaaagcaaa
     2161 gaagacgcgg cttaatctta agctacacag cgtagcctag ctacgaaaaa aactattata
     2221 aaatttaaaa cttatttgga ggaaataaca atggcattga acattgaaaa cattattgct
     2281 gaaattaaag aagcttcaat ccttgaattg aacgaccttg taaaagctat cgaagaagaa
     2341 tttggtgtaa ctgcagctgc tcctgtagct gttgctgcag ctgatgcagc tgatgctggt
     2401 gctgctaaag attcattcga cgttgaattg acatctgcag gcgacaaaaa agttggcgtt
     2461 atcaaagttg tacgtgaaat cactggtctt ggtcttaaag aagctaaaga acttgttgac
     2521 ggtgcaccag cacttgttaa agaaggcgtt gcaactgcag aagctgaaga aatcaaagct
     2581 aaattggaag aagctggagc ttcagttact cttaaataat agagtatcgc aatttgattg
     2641 cggaatccct atttaccagt ctttgagagc gataagcgat tgatagaaac tgataaattg
     2701 atttgctttc ctgccaaaaa ttctttggca ggatttttgt tttaataaac tttcgggggt
     2761 agacactaga ttgtctaccc ctttttttgt gtttcggagg taattatgca aaaggaagga
     2821 cagtcatcac gtcaattcgt gaagagtcat ctcatgacta tcatgggagt tgatattgta
     2881 aaagcaactc agttagttga tgaaatggaa caagtaggtt taatccgatt tgatgaattt
     2941 ggaaatgttg gaattttagt cttggaggga caatcatgaa gcgtattacc gctagtcaat
     3001 atcagacatc agagcgttat tataagctcc ccaaactttt atttgagagt gaacggtata
     3061 agaatatgaa actggaggtt aaggtggttt actcagtttt aaaagatcgg ttggagttgt
     3121 ctttgagcaa aggttggatt gatgaggatg gggctattta tttgatttat tccaattcaa
     3181 atttgatggc acttttaggc tgttcaaagt caaaattact ctccatgtga gtttgaagtg
     3241 acatttttag atgattacca taaaaaacat aactacccac tattttacga atcctatctt
     3301 caaaacatta tggaattcct tgaaagtcag gatataaaga acggagctga tgcctttgta
     3361 gatgatcatc aaaatcttgt ttttgtttta tatggacaag gctatcgagc cgagggaaaa
     3421 gagggaatac ttacaaccca agtaactgta aaagcttatg atgaagacaa gcaaccgatt
     3481 aacttcgcaa atttattaga ttccttaatc gtctcagagt atcaaatgga accgaatctt
     3541 tgggaggtct cccatgattg atctctatct aagtaaaaat agccaaagaa atcaacttct
     3601 tttagacttc ttccaaaact atggcatcga ggtatcttgt cattcagttt ctgaaatgac
     3661 aaaggataaa ttaattgaga tgatgagcta ttcttcagat tgttttgagt ttttatctcc
     3721 caatttatta cgatttaaga accgtgacaa tttaagatta acggatttca ttgaaatgat
     3781 attaaaaaat cctgaactaa ccatcagact tcctcttgca gtttcaaata agagagttta
     3841 tccaaatcta aatttggagg aagctagagc tttattgcca agagatacga aacaattgat
     3901 ttacatggcg caaacacatt atttatctaa ctaaaggaga agcaatatgg ctgaacgatt
     3961 ttgggagaac ttgtccatta ttttggctga aagaaatatc agctggattg agctaaccag
     4021 aaaaatgttt gcgggagagt ttcactatcc aagtgaattg aatcgtttgt atcaaaagat
     4081 tcgtcactac aagatggaac aacgaatgcc tcaaagtcca tgggtagaaa ggattgtgta
     4141 ggtattagat ttagattatg aagatttatt tcggaggtaa ctatgaaaag aataattcca
     4201 gtttatatat tccaacaagt aaatgtccta ttggtatctc tatacttact gaaatttctt
     4261 tgtatcggtg agttaactat actacagatt ctatattgtg cgtcactcat ttctttttta
     4321 tggatgtatg cccaacgtaa acaagcgcat aaggtcaata tgaaatcaag gataaaatgg
     4381 attggtattg gattagccag tctactgatt ataagtctat gttttagtct aatccatgcg
     4441 caagaaagca cgaatcaagc aaacttaatt gggcttcaat atcaagttcc ttggttttca
     4501 tttttattgt tcttaatcaa tgcgagtatg gttgaagaat ttctgtatag agaaatttta
     4561 tggaacttgg ttagaaaatt agatattcga gttgctttga caagtgtttt atttgcctta
     4621 gcacatcatc caggaaccat tatagcttgg tgtttgtatg tatcgctggg gatgttttta
     4681 gggcttgtac gctacaaatt ggacttatgg ggcagtatgg ggttacattt ggtgtggaac
     4741 ctactagttt atagtttgct gcttttttaa aataggtaac ctgattttta ggtaacttct
     4801 aaaactaact tccagttttg ggagagagat ggaagttact ttgaaaagtt acggaaacat
     4861 tattttctat gtgacaacat tgtatcattg cttgcatttt actgctggag agagtataat
     4921 gaaggtggat aaagcactta atcccaaaaa tttaaatagg aggagttagc tatggcagaa
     4981 gaagtattaa atctttaatt agtatctgtt caagttgacg aaacagatga agttgatgga
     5041 atgcgattta gtacattcag tacaaaccgt tgcggtaact ggagtgcttt tagttgggaa
     5101 aattgttaat tcatttaaat tgtaaacttt agagattctc tggagttatg gatgtcgttc
     5161 caatatgtgc acgttggaat gttagtgctt atatgggggg aatccaaagg attctccctt
     5221 tttattttaa taagtctgtc tagctataga tatattaagt ttgatagaat ttcttggaga
     5281 ttttgttatg gattataatt tcaatttgga gcattctttc tttttcacta ataatgatta
     5341 tagtacagat actagcataa agtactaagt aagtctgcct tttaattggc acgaagtaat
     5401 gaataatgat gagtgggttt atcaataccc tattggaaaa tttgttgaaa gacaagggtg
     5461 gaaaatacac attagttcag agtataatag ttcacacgaa ttgttacaag atgtagcaaa
     5521 aatttgccat gaaatgcgaa ttccatttaa acatcttagt acagaagaca aatttatcat
     5581 gcgaaacggg aaattggtta gtcgaggatt ttctggtaaa tttattacat gttatccaaa
     5641 tcaaaatgaa ttagagtcgg ttttgcaaaa gttagaaagt gccttaaagc aatataatgg
     5701 gccatatatt ttaagcgata aacgttggga tgaagtacca atatatctga ggtatggtgt
     5761 gtttaggccg tcaagggatg atgaaaagaa ggttgctatt gatgaattaa ttgttggcga
     5821 tgaagttgtt aaagatgaac gtttaccagt atttaaaatt ccaaaaggta tagtgccccc
     5881 tgactttttg aataaatggc ttgacaagaa agataaaaaa cagggagact ttccctttat
     5941 tatagataat gcaattagat tttcaaacag tggtgggata tataatgcta gactaaaaga
     6001 agatgggaaa aaaataattt taaaagaggc tagaccgtat acaggtctag gatttgatgg
     6061 tacttattct tcagagagat tagcttcgga gtgcaaagca ctaaaaattc taaatgaatg
     6121 gagtgagatg cctaaaatat acttgtacgg taagatctgg gagcacacct tcttaggaat
     6181 tgaacatatg aagggcgttc cactaaatag atgggttacc aataattttc ctttatatga
     6241 agttgttgat aagaccaaag attatctatt gagagtttca aagatagtag aaaaactcat
     6301 cgatttaacg aataagtttc attctgaaaa tgtatatcat caagatttac atttaggaaa
     6361 tatcttggtt aaggatgaag atgagattag tataatagac tgggaacagg ctgtcttttc
     6421 gaatgatgaa aaagttgtac ataaagttgc agcctctggt tttagatcat ggcgagaaac
     6481 atttcccagt gagatagatt ggtatggtat tagacaaata gctcattatt tatacatgcc
     6541 actagtaact acatcagatt tgacatacaa ctatgtaagt caaaccagga tagaaggaaa
     6601 aaaactattt gagtctttgg gttatacaag agaacatata gattatgtag aaagtttatt
     6661 gtcatatcta gattctaaat gtccacagat tgagaatatt tccaggaaaa aagttttaaa
     6721 acccatgcat gagattagaa ctatcgagag tgagcaagat atacaagatt ttattataaa
     6781 agcctttctt ttagtgaact gataggtatt ttcttagcaa acgataaagt tttagggccg
     6841 atacaatcaa ttgcctattc attaaataag ataaatacaa ccaaagattt aaggaaaccg
     6901 tttttaaaat acttaagtgg agagaagaat tttatagacg ctgaacatga taataacgga
     6961 ctgtatactt catcaataga tgagatacac atgaaagatg ttgtatattc tattacacca
     7021 gaaaataaat taagtattga cttctcattt aagtcaccat ttagggtatt attaacagga
     7081 acttctggta gtgggaaaac aacgatttta aatttaatta atggttcttt aaagccacaa
     7141 aaaggttatg taaatttgtt atcacatggg aaaaagagtt cagattcaat accaacagtt
     7201 gatcagacac catatatttt tgacactact attcgtgaga acgtaacttt atttcaaaat
     7261 gaatatt
//
LOCUS       DAVLIK010000073         7164 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLIK010000073 DAVLIK010000000
VERSION     DAVLIK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.073"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..900)
                     /gene="phtA"
                     /locus_tag="VXE87_001926"
     CDS             complement(<1..900)
                     /gene="phtA"
                     /locus_tag="VXE87_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV0843410.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QYREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLS"
     gene            complement(1154..2887)
                     /gene="ptsP"
                     /locus_tag="VXE87_001927"
     CDS             complement(1154..2887)
                     /gene="ptsP"
                     /locus_tag="VXE87_001927"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0843411.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(2893..3156)
                     /locus_tag="VXE87_001928"
     CDS             complement(2893..3156)
                     /locus_tag="VXE87_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0843412.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            3507..3725
                     /gene="nrdH"
                     /locus_tag="VXE87_001929"
     CDS             3507..3725
                     /gene="nrdH"
                     /locus_tag="VXE87_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0843413.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            3806..5965
                     /gene="nrdE"
                     /locus_tag="VXE87_001930"
     CDS             3806..5965
                     /gene="nrdE"
                     /locus_tag="VXE87_001930"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0843414.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            6153..7115
                     /gene="nrdF"
                     /locus_tag="VXE87_001931"
     CDS             6153..7115
                     /gene="nrdF"
                     /locus_tag="VXE87_001931"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0843415.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNCGLD"
BASE COUNT         2078 a         1538 c         1335 g         2213 t
ORIGIN      
        1 actcaaaggc agtttgtaga gctgtttcaa gagactatca atgtcattac tttgacttgc
       61 ttgactgtta gtgttgctgt tgttgcttgt gttagtattt gtagttcctg gattgcttac
      121 agaaggtacc cagtttgttc ttgaagtgtt atcgctattt tgtcggcgat aggttcttga
      181 atttgacaga tttccccgac cagataggaa ggcttctgca gcagctaact cgctagctga
      241 taactcattc ttaggaatgt aatggtaatg gtcgccgtga ggaacgatat aagcatcacc
      301 agtatcctct atgatatcag aagcattaaa gatataacca tcatctgtag tatagcgtcc
      361 ttgcgaacgt gccaaggcaa cagctccatc gtttcttgga gtccctcctt cacgatactg
      421 actatgttct tgtttttgtc gattgatttc ctcttttgta cggacgttat ccgcgtgggc
      481 agcatcctta aggtaaacat agtattttcc atctaccttg ataacatatc cacccttgac
      541 ctcattaaca atatcctcat cttttagctt atagtttgga tctttcatga gtaattcttc
      601 actgaaaatc gcatcataag gaaccttacc attgtaataa tgatagtggt cgccatgtga
      661 agtgacatag ccttggtctg ttatcttgat gacgatttgc tcagcattga ttccttcacg
      721 cttgctaacc tcatcaggag tcaaattctc cgttttttgc gtcgcttgtt ttccatctat
      781 ataggaaaca cgattatttt ccttaaccgt tctagcttga tacagtccca actcgtaaga
      841 acaaacactt aaaatcaaag ctgccgcaga accaacaagg tatttcttat taattttcat
      901 cgaaactctc tttctatttg atatttctag ttgcaattca tttctaaatt gcagaaactc
      961 ctctctatta cttaactggt taatagttta ctcctaaatc tccaacttgt caagaatttt
     1021 atgaaccatt taagtatttt ttgttctgac cactactttt tcaaggttgg actttctata
     1081 aaaaagattt tcttgaaaat tctttttaaa atatcaaaaa aatccctgta actgagttgc
     1141 agggacttgt cgattaatca aaattaacgt attctttttg aagttcaaga acttcttcca
     1201 ttgttgagca ttctgtaagg gcacggtttg cgtactcttc catcttagct gtgtcgagtt
     1261 tcttcatcaa gctgcgtgta cgaagtacag atgttgctga catagagaac tcatccaagc
     1321 ccattccgac aagaagtgga acagcttgtt ggtcaccagc catctcacca cacataccag
     1381 cccatttacc ttcagcgtga gctgctttga tcacattgtt aatcaagcgt aggattgatg
     1441 ggttgtatgg ttggtaaagg tatgaaactt gttcgttcat acggtctgct gccattgtat
     1501 attggatcaa gtcgtttgta ccaattgaga agaagtcaac ttctttagca aattggtctg
     1561 caagcatagc cgctgcagga atctcaatca tgataccaac ttggatgtta tccgcaactg
     1621 caacaccttc agcaagaagg tttgcttttt cttcatcaaa gactgctttc gctgcacgga
     1681 attctttcaa gagcgcaacc attgggaaca tgatacgcaa ttgaccgtga acagacgcac
     1741 gaagaagagc acggatttgt gtgcggaaca tagcatctcc agtctcagag atagagatac
     1801 gaagagcacg gaatccaagg aatgggttca tttcgtgagg catatcgaag taaggaagtt
     1861 ccttatctcc accgatatcc attgtacgaa cgacaacagg tttaccgttc attccttcaa
     1921 gaacagcctt gtatgcttca tactgctcat cttcagttgg gaagtcttga gaatccatgt
     1981 acaagaactc tgtacggtaa agtccaacag cttctgcacc gttgttgtta acaccttcaa
     2041 cgtcttttgg agtaccaata ttggcagcca actcgaagtg tttaccgtca gcagtcactg
     2101 tttgagcatc tttcaaaagt gcccattcag ctttttgttt cgcataggct tcaccagctg
     2161 ctttaaattc tgccgcttgt tcatctgttg ggttgataat cacttctcca gtgatcccgt
     2221 taacagcaag gatgtcaccg tctttaacga tttcagtgat gttatttgta cctaatacag
     2281 cagcaatttc aagtgtacgt gccatgatag ctgagtggct tgtacgtcca ccaatgttgg
     2341 ttacaaaagc ttttacaaag tttttgtcca attgagctgt atctgaagga gtcaagtcat
     2401 gcgcaatcac aatcacttct tcattgatag aagctgggtt tggcaatttt ttaccaagaa
     2461 ggtttgccaa tacacgtttt gtcacgtcgc ggatatccgc tgcgcgttct tgcatgtatg
     2521 ggttgtcttc catgccttca aagatagtga taaacatatc tgtaacttct ttcagacctg
     2581 cttctgcatt cactttcttc gcacggatag tttccttgat ttggctgatc atttctgggt
     2641 cagcaagaac cattaagtga gcatcaaaaa cttgagctgc ttcttcaccg agcgtaccta
     2701 ctgctttctc gcgaataaca gaaagctcgt cttgtgatgc ctgtagagcg gcatcaaggc
     2761 gagcttcttc tgcgtttgta tcttcgactg taatagtctc aaatgacaaa tccggctgaa
     2821 cgagtagata tgcttttgca actgcaacac cgtcagatgc tgcgattcct ttaagcattt
     2881 ctgtcatttc ccttatgcca atccttcttt ttccattgtt tctgagattg cagcgatagc
     2941 gtcatctgca tctgcacctt cagctgagat agttacgtca gcaccttgac caacaccaag
     3001 actcataaca cccataattg atttaaggtt aactgattta cctttgtact caagagtgat
     3061 atctgaagca aatttgctag cagtttgtac caacaatgtt gctggacgtg cgtgaatacc
     3121 tgtttctgcc actacgtgga aatctttaga agccatagtt tgactctcct tttgttcttt
     3181 ctttttttga gttatatgtg ataaccctta caatttagta ttataccatc ttctaggatt
     3241 tttttcaagc attttctgga ttttccttca atttcctttc agataacttg ctgaaaatct
     3301 tctatcctag ataacaaaac acaggatata gtttcttcaa aaacaattta taggataatc
     3361 attgctattt cacaatacaa acactatata ttgtgtttat atataaaaac aacaaaagaa
     3421 caccactata tttagtttaa atcattgaca aaattttatt ttctgatata ctaagatagt
     3481 attaaatttt gaagaggagt tacacaatgg taaccgttta ttctaaaaac aattgtgtcc
     3541 aatgtaaaat gaccaagcgt ttcttggaca gtaataatgt ctcttatcgt gaaatcaatc
     3601 ttgatgagca acctgagtac gtcgatcaag ttaaagagct cggttttagc gcagctcctg
     3661 ttatccaaac accaactgaa gtcttttcag gtttccaacc aggaaaactg aaacaattag
     3721 cataatctta gtacatcatc cagaagaaac tgcttttagg gctaacttag aagcctttct
     3781 tttgtaatta gataagggaa attttatggg attaaaacat cttgaagacg tgacttactt
     3841 ccgtcttaat aacgaaatta accgtcctgt taatggacaa atcatgcttc ataaagataa
     3901 ggaagccttg gatgctttct ttaaagaaaa tgtagttcca aacactatgg tttttgattc
     3961 aatcaaagac aaaatcaatt acctcattga acacaactac atcgaaacag cctttatcaa
     4021 gaaataccgt ccagagttct tggaagaatt ggctcaattt atcaaagacc aaaacttcca
     4081 attcaagtca ttcatggcag cttataaatt ttacaatcaa tatgccttaa agactaatga
     4141 cggtgaatac tatcttgaaa atatggaaga ccgtgtcttc ttcaacgccc tttatttcgc
     4201 tgatgggaat gaagctgttg caatcgatat tgccaatgaa atcatccacc aacgctacca
     4261 acctgctact ccttccttct tgaatgctgg acgtgctcgt cgtggggagt tggtatcttg
     4321 tttcctaatc caagtgacgg atgatatgaa ctctatcggg cgttctatca actcagctct
     4381 tcaactttca cgtattggtg gtggtgtggg aattaccctc agcaaccttc gtgaagctgg
     4441 tgcacctatc aaaggctatg aaggagctgc ttcaggtgtc gttcctgtta tgaagctttt
     4501 tgaagacagc ttctcttact ccaaccaatt ggggcaacgt caaggtgccg gcgttgtcta
     4561 cctcaacgtc tttcacccag atatcatcgc tttcctttca actaagaaag aaaacgctga
     4621 tgaaaaagta cgtgtcaaga ctctatcact tggtgttgta gtacctgata aattctacga
     4681 attggctcgt aaaaatgaag aaatgtacct cttcagccct tactctgtag aaaaagaata
     4741 cggtgtgcca ttcaattaca tcgacattac tgaaaaatac gatgaattgg tcgcaaatcc
     4801 aaatattcgc aagacaaaaa tcaaggcgcg ggatttggaa actgaaatct ctaaattgca
     4861 acaagagtct ggctatcctt atgtagtcaa catcgatacg gctaaccgtg caaatcctgt
     4921 tgatggaaag attatcatga gtaacttgtg ttctgagatt cttcaagttc aagaaccaag
     4981 cttgatcaac gatgctcaag aattccttca aatgggaaca gatgtttcat gtaacctggg
     5041 ttcaaccaac gtggttaaca tgatgacttc acctgatttt ggtcgttcta tccgtgctat
     5101 ggttcgtgcc cttactttcg ttacagatag ttcacatatc gtagctgtac caacgattga
     5161 ccatggaaat agccaagccc acacctttgg tctcggtgcc atgggactgc acagctacct
     5221 tgcccaacaa ctcattgaat atggttcacc tgagtctgtt gaatttacaa gcatctactt
     5281 tatgcttatg aactactgga ccttggtaga gtcaaacaat attgcacgtg aacgtggtat
     5341 taccttccac aactttgaaa aatcagacta tgctaacgga agttactttg acaagtatgt
     5401 aactggtgaa tttgttccaa catcagaccg tgttaaagaa ctcttcaaaa atgtttttat
     5461 ccctggtgtt gctgattggg ctgaacttcg cgacaaggtt caagaagatg gtctttacca
     5521 ccaaaatcgc cttgctgtag cgccaaatgg ttctatcagc tatatcaacg acgtttctgc
     5581 ttctatccac ccgattacgc aacgtatcga agaacgccaa gagaagaaaa ttggtaaaat
     5641 ctactaccct gctgctggct tgtctacaga aaccattcct tactacactt ctgcctacga
     5701 tatggatatg cgtaaagtca tcgatgttta cgctgctgcg actgaacacg tggatcaagg
     5761 actttcactc accctcttca tgcgcagtga cattccaaaa ggcctttacg aatggaagag
     5821 ggaaaataaa caaacgacac gtgatttgtc catccttcgt aactatgcct ttaacaaggg
     5881 aatcaagtct atctactacg tccgtacctt tacagatgac ggtggagaag tcggcgccaa
     5941 ccaatgtgaa agctgtgtga tttagtttct agcatagaaa cattattttt ccctaagcag
     6001 cactgataaa atcaaatcta ctatgtcata atataattta tgtaacattt taaaagtcgg
     6061 gcttccgact ttttgtgcga tactcctata gaattatggt aaagtagaaa taattgtgag
     6121 ttcgcaatac taaacacaga aagagatttt aaatggaaac ttactacaaa gccattaact
     6181 ggaatgccat cgaagatgtc atcgacaaat caacttggga aaaactgacg gagcaatttt
     6241 ggctcgatac acgtattccc ttatcaaacg acttggatga ctggagaaag ctatctaaca
     6301 aagagaaaga cttggtcgga aaagtttttg gtggtttaac ccttcttgac actatgcaat
     6361 ctgaaactgg ggttcaagcc cttcgcgcag acatccgtac accacatgag gaagctgttt
     6421 tcaataacat ccaatttatg gaatctgtcc acgctaaatc ttactcatca atcttttcta
     6481 ccttgaatac taaggctgag attgaagaaa ttttcgaatg gaccaatacc aatccttacc
     6541 tacaaaagaa ggctgagatt gtcaacgaaa tctacctaaa cggcagccca cttgaaaaga
     6601 aagttgccag cgtcttcctc gaaaccttcc tcttctactc tggtttcttc actcccctct
     6661 actatctcgg taacaacaaa ctagccaacg ttgcagaaat cattaaattg attattcgtg
     6721 acgagtctgt tcacggaacc tacattggtt acaaattcca acttggtttc aatgaattgc
     6781 ctgaagaaga gcaagaaaaa ctcaaagaat ggatgtacga cctactctat actctttatg
     6841 aaaatgaaga aggctacaca gagagtcttt atgacggtgt tggttggact gaagaggtta
     6901 aaaccttcct tcgctacaat gccaataaag ctctcatgaa catgggacaa gatccacttt
     6961 tcccagattc agctgaagat gtcaacccaa tcgttatgaa cggtatttca acaggaactt
     7021 ccaaccatga cttcttctct caagtcggaa atggttacct tcttggcgaa gttgaagcca
     7081 tgcaagatga tgactacaac tgcggtttgg actaatactc ttcgaaaatc aaattcaaac
     7141 cacgtcagct tcgccttgcc gtac
//
LOCUS       DAVLIK010000074         7080 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLIK010000074 DAVLIK010000000
VERSION     DAVLIK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7080
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.074"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..2464)
                     /locus_tag="VXE87_001932"
     CDS             complement(<1..2464)
                     /locus_tag="VXE87_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0843416.1"
                     /translation="MDALTRRQFDRAMFAKNRTLAIRVGDYASQDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVLEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQISGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGVEAKVQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIVNDIRPKQAQAETEIAKQVEALSRTKNELAGASTLFAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEA
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELSSKIASVQA
                     SGRNLFLNSLFKQDISKTGIWTTSTYTAAIDSESKYLGHKALKIIGLNPSGRDGGNPK
                     VTYPALGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIK
                     RYVVHIPKGWTNESKQTTNEWLFNFNQEGTIWIWMPKFEISDVDTSYSEAPEDIEGQI
                     STVESNFKQRADSLEAGVSRLTE"
     gene            complement(2469..2819)
                     /locus_tag="VXE87_001933"
     CDS             complement(2469..2819)
                     /locus_tag="VXE87_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843417.1"
                     /translation="MAQLTINGVAVKPPKSFKVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            complement(2828..6433)
                     /locus_tag="VXE87_001934"
     CDS             complement(2828..6433)
                     /locus_tag="VXE87_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843418.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSIATIGLGIGVFLAESIANG
                     LGRQKERIIKALVALFDNIGNIAEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKDFEKVVVTNAPKISSIFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSNTFGISIETVADL
                     LGGIILEALKLLADTIKLVADGFTAFSDWCKENKEIISTIASVIGTLATVWQGIKFLS
                     WAEQAGGLAGAFELLSSKVSFIVSGIKNLGLALKALTFDKLVSFGETIYLNALYAKDF
                     VVNSGKTIAQLGKTALELGKSALAWTAHTAKMGLATAAEFAHSVAAGVATAATWAFNA
                     ALAVLTSPITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEF
                     FSGLWTKLQEIFEPIGQWFGEKFQQAWDAIVNIFTPIGSWFGQRWADVTSALANIGAW
                     FTDMFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGNMFTSAYNAVKNAFSS
                     IGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFRSAVNGVLGTIENVVNGFIGMINGVIG
                     MINKIPGVSLGGIGYVSLPRLARGGIVDSPTIAMIGEAGKEAVVPLENTGFIQTLGRV
                     VSSAVVNAMAGISPQGGFSGDGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
     gene            complement(6420..6770)
                     /locus_tag="VXE87_001935"
     CDS             complement(6420..6770)
                     /locus_tag="VXE87_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843419.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYI
                     LSRMITNHVSLLLSNDAKIVELWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            complement(6809..7069)
                     /locus_tag="VXE87_001936"
     CDS             complement(6809..7069)
                     /locus_tag="VXE87_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843420.1"
                     /translation="MPEAGEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYV
                     DNGGDQTTFMTEVLMPLFEVSGFTPRGSKDKKTSKKKMTVVE"
BASE COUNT         1881 a         1771 c         1318 g         2110 t
ORIGIN      
        1 cttcagtcag acggcttaca ccagcttcga gtgaatcagc acgctgttta aagttggatt
       61 caactgttga aatctgacct tctatatctt caggagcttc tgaataagaa gtatctacat
      121 cgcttatttc aaacttcggc atccaaatcc aaatggttcc ttcctggttg aaattgaaca
      181 accattcatt tgtggtctgc ttggattcgt ttgtccaacc ttttggaata tggacaacat
      241 atcgcttaat ttctgtcgac aatgtcacat ttccagtttt atatccgata ttccctaatc
      301 gagatcttag cattattcca tttttatttg ccttagcata aaaactaatg gttacatctt
      361 gattagtcgt acttccggga attactttcc cgaattgacc cagagctgga taagtaacct
      421 tgggattacc tccatcacga ccagatggat tcaaacctat aattttaaga gccttgtgtc
      481 caagatactt actttcgcta tcgatagcag ccgtatatgt actcgttgtc caaattcctg
      541 tttttgaaat atcctgcttg aatagtgagt tcaagaatag atttcgaccg gatgcctgca
      601 cactcgctat cttactagag agctcctcag ctgtctgcgt gagttctgac ttgctggctt
      661 taccattagc caagttggtc agttctgaca gtctacgagt cgtcgtctcc tcatacgtcg
      721 cttgcgctga cttcacgcca gccagttcat ttttagtccg gctaagtgct tcaacttgct
      781 tggcaatctc agcttcagcc tgtgcttgct tcggtcgaat atcgtttgcg atagttcgtt
      841 ttagaacatc caagtcacct gacagagccg tttgtgcgct cgtagtctgc gacttaaacg
      901 cttcaagtct agcgacagaa tccagctcaa tccgcttagc ttcctgtgca aacagggtac
      961 ttgcgccagc cagttcattc ttagtccggc taagtgcttc aacttgcttg gcaatctcag
     1021 tttcagcctg tgcttgcttc ggtcgaatat cattcacgat agtccgtttc agagcgtcca
     1081 agtcacccga cagagccgtt tgtgcgctcg tagtctgcga cttaaacgct tcaagtctag
     1141 cgacagaatc cagcccaatc cgcttagctt cctgtgcaag cagggtactt gcgccagcat
     1201 ttcgcaaagc ttcctcagcc ttgcgcttag cttctttcaa tggcccgttg tcaaagctat
     1261 taaagcgctg attgatagtg tcagacagtt ctctcttgac ttcttcagct ctggctttgg
     1321 ccagttctac ttgatcgtta aagtcttttt tgattttgtc gaccttttgg tcaaaatctt
     1381 tatctgctgc ttcaatctgc gcttggactt ttgcttcaac gccatcttgt tgctttatct
     1441 gcttggtaat cgttccctcg taagaatact gagtatcatt tccagcttta ctatctgcgc
     1501 tgatacgacc tctcagacca cctttgaaag taaagctctg acttaagaca ggaactttaa
     1561 aggtctcttt cttattggtc tgaatggtta cccactgccc aacctcaagc agtaaatgcc
     1621 cttggtagtt gagattatac ggatagtaag ttaggttttt cagtttgtaa tacaggtcat
     1681 ttaaagcact ctgggtcatg aagacattgt ccagttccaa agaccgacct gtcttcatac
     1741 cgaccgtcag agacttcttg tccgtcttac aagtgatacc agatatctga tactcaatct
     1801 cactcttggt caagccatgc aagaagtaac tgtcagcgtt gatcgtgata ttggactcag
     1861 tcaaatcacg gatttccatc ttgccttctc tgttgaagaa acaagacatc ccaatcatct
     1921 gagtcatagc gctcagcata tccctgaacg aaagtttctt accttcaaga acttgctcga
     1981 tatggtaacg catagcgctg attccgaaat agtcattcgc taactcaatg cctgttttca
     2041 ggcagatttc ctgaataacc tctcgtactt cagctgggaa atgcaagtcc gtcacgtact
     2101 cacgattgag cttaaacata ccgtccataa gttcaagcgt ggtagtgttt cggtttcggt
     2161 caatctcaat atcgttgatg aagtattccc ccatcttgac ccactggtag gtatccccaa
     2221 ccagtagacc aatctcaggg tgcagggtat ccagcttatt gaacgtggta atgatgctgg
     2281 taaaggtaat tttaccgcta ccagcgcagg ttccaccagg cttataagta tcgcccttaa
     2341 tgtagccata ctcaaagcta gcctctttga tatcctgtga agcataatct ccaacacgga
     2401 tagccagcgt cctgtttttg gcaaacatgg ctctgtcaaa ttgtcgtcta gttaaagcgt
     2461 ccattttctt acctctctac cagattaaat ttagcgccag accaaggttt aaacttctca
     2521 gtaaaggtat agctaggagc tgtcctatca ccgacataga aagtctttgt gacttggcca
     2581 tccatggggt ctggataaga cacctcaaaa aattcagatg atacagcatg taaaagctga
     2641 cttatttctc cctgagtcat cataccccat tcacagtcta gtttgcgttt ggtcgtgata
     2701 cggtcacgca ccatgtcgcc attggcatta cgccctgtct ctccatcgat atcttgaata
     2761 ccgactttaa aagatttggg aggcttcaca gccaccccat tgattgtcaa ttgtgccatt
     2821 taacctccta aatcttgagc aaggtttgac ctgctcgttc atgttccttg ttgatttctt
     2881 ggatagctac ccgtccgaac tcatggcctg cgatttgaat aacgatgtcg ccgtcaccag
     2941 aaaaaccacc ttgtggacta ataccagcca tggcatttac taccgcactg ctgacaactc
     3001 gcccaagggt ttggataaag cctgtatttt caagtggtac gaccgcttct ttaccagctt
     3061 caccaatcat ggcgattgtt gggctatcga cgataccacc acgggcaaga cgaggtaggc
     3121 tcacatatcc aataccacca agggatacgc caggtatttt gttaatcatg ccaataacac
     3181 cattgatcat gccgatgaag ccattgacta cattttcaat agtcccaaga acaccattga
     3241 ctgcacttct gaaagcccca cctacagcgc taccaacctt ttgtccagca ttgacaaata
     3301 tgctttgaac cgttgaccat acaccgctga agaagccacc aattgaacta aacgcgttct
     3361 tgactgcatt ataagcacta gtaaacatat tcccaaacca agaagataca ttcgcaagaa
     3421 cacttgtaac atctgcccat ctctcgccaa accataaacc tagtttgcta aagatgtttg
     3481 ttagaccagt ccatgctttt tggaacatgt cagtaaacca tgccccgata ttagccaagg
     3541 cactagtcac atccgcccaa cgttgtccaa accatgagcc gattggtgtg aagatattaa
     3601 cgatagcatc ccatgcttgc tggaacttct cgccaaacca ttgacctatt ggctcaaaga
     3661 tttcttgtag ttttgtccat agaccactga aaaattcgcc aatagctcga caaataccac
     3721 taataaaatc acatagtcct tgccatgcag ttttagcaaa ctcaacaaca gtgtcccagt
     3781 tttggtagag caagacacca atagcaatta aggctgcgat tgctgcaata atccatgtta
     3841 ttggacttgt caaaactgct aacgctgcat taaaagccca tgttgcagct gtagcgactc
     3901 ctgctgccac agaatgtgca aattccgccg cggttgctaa tcccattttc gctgtatgag
     3961 cagtccatgc tagagctgat ttaccaagtt ctaaagcagt tttccctagc tgtgcaattg
     4021 ttttacctga attgacaaca aaatcttttg catacaacgc attcaaatag atggtttctc
     4081 cgaagctgac caatttatca aatgtcaaag ctttcaaagc tagtccaaga tttttaattc
     4141 cgctaacaat aaaggaaacc ttactactta ataattcgaa tgcccctgca agtcctccag
     4201 cttgttcagc ccaagacaag aacttaattc cttgccacac ggttgcaagc gtaccaatca
     4261 cactagcgat tgtggagata atctctttat tttctttaca ccaatctgaa aaagcagtaa
     4321 aaccatcggc tactagcttg attgtatcag ctagtaactt caatgcctct agtatgatac
     4381 cgcctagtaa atcagcgacg gtttcaatac ttatgccgaa tgtgttagac aagaactctg
     4441 caaaaggttg ccaggaattc tcccagagaa tctgaataat gtcaattagc ccattaaaag
     4501 cattagcaat agagttaata gcaggggcta catgttcatc ataaacacga cttaagccat
     4561 cgccaaattt gttaacagac ctttcaatgc tctcaaatac aggcgcaaca gtatctaata
     4621 aactttggaa gattgatgaa attttaggag cgtttgtcac aacgactttt tcaaaatctt
     4681 taaacaaact tcctgctaat ttactaccaa cttcaacaat ggtagatgtc aaactcaaca
     4741 gagttgacac aatagcgcta ccgatacgaa ccgcaccagt tgaggtaatg acgtcgtaga
     4801 aagcactaga aaagtcctga gcgatgtttc ctactgcctc ggcaatgtta ccaatattat
     4861 caaacaaagc gactagcgcc ttgataatgc gttctttttg ccttccaagg ccattggcaa
     4921 tactttcggc aaggaaaaca ccgataccta gcccgatagt agctattgag cctgtcactt
     4981 gccctaaagc ataagcaatt ttctcagcca ttcggttaaa ggcattcaca acccttgggt
     5041 cagtggcgat ttctcccatt gtcttagcta tttggtctaa ggcagtctta atgcgtttta
     5101 taccttctgg tctaaatgct gcatcaaaac ctttcttgaa gaggtcaaac aaccctttga
     5161 gcttatctcc aagaccatca aaaatgctct tgaatttgtt gtccatgtcg gtcaactcga
     5221 cttctggcaa gatgtcttta aaaggtccgc caccgcctcc ctttccttta ccacctttgc
     5281 caccgcctcc agacccgcct gcgtcgtcat cttttggttt ttgcaagatg ttaatctcat
     5341 caaatcccaa aagacctagc aactctttag cggccttctt agcgtttttg gcggagtctc
     5401 caagattgtc agcaagtcct cctgctgaat ctccagcgtc gtctactgcg tcagcaaggt
     5461 ctcctgctcc gcctgcagca tccttcatgg cgttacccat gtctccaact gctccaccaa
     5521 caccatcttt cactgttgct ttcttgttga acatcaaagc gataaactca gcgagtttag
     5581 cagtaacgtt ctttaagacc atagcaaaag agttcaagac aggcataatg gcattgataa
     5641 tcggtaacat agagttacca aggttcaatg ctgcgtcctt cattagcgac ttaaacagac
     5701 tgatacgacc atttacagaa ttagacaagg tatctccata cttggctgta gcttgctcca
     5761 ggatagccat aagacggatt tgttgctggg tttggtagtc taattgttgc cagctttgtc
     5821 cgtttgcgaa cttcttaaaa gcttcagtgg acttaatcat agccacattg acgttgattc
     5881 ctaggtcctc aattgcttcg gtgttcccta gtagacctga gcgaatccgc tccataacgt
     5941 ctgtaatcgt gcgccctgaa ccttcagcaa ccactgccga tgtctgcaac atcttagcag
     6001 tataggcgct tagcttgttg gtatctttga taaatccaga aaataagttt gaatagactg
     6061 caccgtagtt ggtcgcctca cccactccca tattcatagc gttggcgtta tcgttaaccc
     6121 atttcaagaa agattgcgaa ctctcgccca tctgtcgctt gatttggttc atagacgctg
     6181 acacttcaag agctgtctgc gttgaataca ttccaacatc aagtaatttc ttaccaagga
     6241 ttgcaaaacc agcaaactta gccagcttac caaacgcact accgattgag ttcgactgtt
     6301 cacgaacttt ggcagtggca tttttcactt ggtcagatgt tcctttgacc tgattctcga
     6361 cttctttcat ctttttcctg aaaggcgcta tctcagcgtc aatcatgacc ttcaattcat
     6421 caagagttgc catttacttc ctccttcctt tttcgattat gtctctctgc aaaatcacgc
     6481 atccgttcct tatgcaacaa aagcgcttgt ctctgtcgtt cctgttctac tgcttgctgt
     6541 tcttctacaa acaactcagg cgcatattcc caaagctcaa caatcttagc gtcattggac
     6601 agtaataagg aaacatgatt agttatcatt cgcgaaagta tgtacgagtc aataatcttt
     6661 tctttacgct cttggatttt gacacggttg tagctttcta tcatttccct gatttcaagc
     6721 accgttaaat cccaaaaatc aagaggcttg cccccgatgt ctaaaaacat aggataaagc
     6781 ctctcaataa tctgcgttac cgttaagatt actcgactac tgtcattttc ttcttggaag
     6841 ttttcttgtc cttgcttcct cgtggagtaa aacccgatac ttcaaatagc ggcatcaaca
     6901 cctctgtcat gaatgtcgtt tggtctccgc cgttatccac gtattcatcg tataggtcgt
     6961 agacatcttc aaaggaatac ccatgttcat actgctgcaa ggctccatga actaacaaca
     7021 gcataacttt caaaggcggt aaagtgaact cttcgccagc ttcaggcatg aaaatcttta
//
LOCUS       DAVLIK010000075         6808 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLIK010000075 DAVLIK010000000
VERSION     DAVLIK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.075"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            214..483
                     /gene="blpJ"
                     /locus_tag="VXE87_001937"
     CDS             214..483
                     /gene="blpJ"
                     /locus_tag="VXE87_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV0843421.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            552..782
                     /gene="blpU"
                     /locus_tag="VXE87_001938"
     CDS             552..782
                     /gene="blpU"
                     /locus_tag="VXE87_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0843422.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            785..904
                     /locus_tag="VXE87_001939"
     CDS             785..904
                     /locus_tag="VXE87_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0843423.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            1201..1365
                     /locus_tag="VXE87_001940"
     CDS             1201..1365
                     /locus_tag="VXE87_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843424.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            1362..1766
                     /locus_tag="VXE87_001941"
     CDS             1362..1766
                     /locus_tag="VXE87_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0843425.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            1964..2768
                     /locus_tag="VXE87_001942"
                     /pseudo
     CDS             1964..2768
                     /locus_tag="VXE87_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            2918..3172
                     /gene="blpM"
                     /locus_tag="VXE87_001943"
     CDS             2918..3172
                     /gene="blpM"
                     /locus_tag="VXE87_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV0843426.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            3188..3391
                     /gene="blpN"
                     /locus_tag="VXE87_001944"
     CDS             3188..3391
                     /gene="blpN"
                     /locus_tag="VXE87_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV0843427.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            3635..3784
                     /gene="blpO"
                     /locus_tag="VXE87_001945"
     CDS             3635..3784
                     /gene="blpO"
                     /locus_tag="VXE87_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0843428.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            3888..4007
                     /locus_tag="VXE87_001946"
     CDS             3888..4007
                     /locus_tag="VXE87_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0843429.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            4793..5212
                     /locus_tag="VXE87_001947"
     CDS             4793..5212
                     /locus_tag="VXE87_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0843430.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKTNCLLNLTAVESDKVRS"
     gene            5227..5916
                     /locus_tag="VXE87_001948"
     CDS             5227..5916
                     /locus_tag="VXE87_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0843431.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFSGVMIWILVKTGHGYLFRIPRKKWLWYSILTVLVLVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            5958..6191
                     /locus_tag="VXE87_001949"
     CDS             5958..6191
                     /locus_tag="VXE87_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843432.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            6522..>6808
                     /locus_tag="VXE87_001950"
     CDS             6522..>6808
                     /locus_tag="VXE87_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843433.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPK"
BASE COUNT         2086 a         1002 c         1373 g         2347 t
ORIGIN      
        1 actttttatt gcaaggagaa taacgaaatt aagatatttt agatactcaa gattattgaa
       61 atcttagact aaaaaatagg tactgctacc tttaagaaga tagtagacgt gtatactttt
      121 ttaagaaaat caaaaagata ctataaaaaa tctatttgtt tattgaattt aagactttgg
      181 taacaaattg aaaataaaaa ggaggtattc atcatgaata caaaaatgtt gtcacagtta
      241 gaggttatgg atactgaaat gcttgcgaaa gttgaagggg ggtatagctc cactgattgt
      301 caaaatgcac tgattacagg agtcactacg ggaattataa ctggtggaac tggagcaggt
      361 ttggccactt taggagtagc tggacttgct ggtgcatttg ttggagcaca cattggtgca
      421 attgggggtg gattaacatg cttaggaggt atggttggtg ataaattggg actaagttgg
      481 taagacttat agtaaaatta tgaggattct attctgattt attttagttt tttaaaaaag
      541 gagtatttgt catggataca aaaatgatgt cacaattttc tgttatggat actgaaatgc
      601 ttgcttgcgt tgaaggtggc ggatgcaatt ggggagattt tgccaaagca ggtgttggag
      661 gagcagcagc aagaggtctt caactaggca ttaaaacagg aacatggcaa ggtgcagcaa
      721 ctggtgctgc gggtggagct atacttggag gtgtagccta tgcagcaaca tgttggtggt
      781 aattatggat tttaaaagtt ttattattgg tttagtagtt ggtatatttg gtccttatat
      841 ggataattta attagaaaaa tattttcaaa atttcccaaa aaggatacag atagtacccc
      901 ctaaaaaata aatttctccc ctgtatttgc tagcttaatt tacaggggag tttctttaat
      961 tttgtttcgc ctgtcaaaat gatatgtgat agcaggatga aaagtctgca aacaagttgg
     1021 tatcaataca atataaagag gaaagtatgt ttttcatgct tgctttttta atttttacaa
     1081 ttcaagaggt tttgatgacc atttatgatt tgagtgatcc aaggtcaaaa taagtgctat
     1141 actagcagtg taaatgttct tgctcaacta agataaatcg cacatttagg aggaaatctt
     1201 atgaagaaaa aaatactgat tattttcgtt ctgtatctaa tcatgtccat ctttctatat
     1261 ccgcttaggg agagtgcttg gtatcagcta ttttatacca tagcctatgt gattgcagtt
     1321 atgatctatt ttgctatcaa taaaaagaaa ggagaaaaga aatgaaaact tttcttgcta
     1381 aaaaacggaa catcttcctt gcgagattgt tcttaggtca gttgcccttg cttgtttcta
     1441 cttatctatt tctatctcgt cagtttttaa atttttccgt agttttccaa tttcttttag
     1501 tagttattaa cttggcttct attttggtta ctgtttatct cactagggaa atgaggataa
     1561 gagagtttga agatgatgat ttggttagtc ctagaaccaa tcaacttatg tttatcggct
     1621 tgacaggttt tatgtctatt atttgtttgt atagaggtat cacagcagga gaatcttatc
     1681 aacaactaat cgcttatatt ggcgctgttc tctgcttaat catcatgctt ctgctcatgt
     1741 ggggcttgaa gtattataaa aagtagagct taatgaagta taaaagaaaa gggtaagtgt
     1801 ttttgcaata cttacccttt tataatagat tccctgcgaa acaaaatatg gtatagtata
     1861 ttgaaactag aatagtacgc ctctacttct aaaacattgt tagaaatcga tttgactgtc
     1921 ctgatcgatt tatcctgttc ttatttcatt ttactatagt tctatgaatt atgaagcaag
     1981 taaacaacta actgatgcac gatttaagct ccttgttggt gttcagcgta ccacttttga
     2041 agagatgtta gctgtattaa aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa
     2101 acctaaatta agcctagaag accttcttat ggccactctt caatatgtgc gagaatatcg
     2161 aacttatgaa caaattgcgg ctgattttgg tatccacgaa agcaacttta tccgtcggag
     2221 ccggtgggtt gaagtaactc ttgttcaaag tggtgttacg atttcaagaa ctcttctcag
     2281 ttctgaggac acggtaatga ttgatgcgac ggaagtacaa atcaatcgcc ctaaaaaaag
     2341 aattagcgaa tgattctggt aaaaagaaat ttcacgctat gaaggctcag gcgattgtca
     2401 caagtcaagg gagaattatt tctttggata tcgctgtgaa ctatggtcat gatatgaagt
     2461 tgttcaaaat gagtcgcaga aatatcggac aagctggtaa aatcttggct gacagtggtt
     2521 attaaggact catgaagata tatcctcaag tacaaactcc acgtaaatcc agcaaactca
     2581 agccactaac agttgaagat aaagcctgta accatgcgct atctaaggat agaagcaagg
     2641 ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgat ttcaacaacc tatcgaaatc
     2701 atcgtaaacg cttcggatta cgaataaatt tgattgctgg tattatcaat catgaactag
     2761 gattctagtt ttgcaggaag tctaatgtaa tttttgcaat tcaagacgtt tcgatgacta
     2821 ttcaagatct ggatgaaaaa ttttaaaaaa cgatgatata ctaaacttgt caaagttaca
     2881 acaagacaaa aattaaaaat aaaaaagagt atttgtcatg gatacaaaaa ttatggaaca
     2941 atttcatgaa atggatataa ctatgttatc tagtattgaa ggaggcaaga ataattggca
     3001 aactaatgtc ttagaaggtg gtggtgctgc ttttggtggc tgggggctag gaacagctat
     3061 ttgtgctgcg agtggtgttg gagcaccatt tatgggagca tgtggataca taggagctaa
     3121 atttggtgtg gatctttggg caggagtaac aggggcaacg ggtggatttt aataaaagga
     3181 gacttgtatg aatacttatt gtaatataaa tgaaacaatg ctgagtgagg tttatggagg
     3241 taattccgga ggagcagctg tagttgctgc tttaggttgt gcagcgggtg gagtgaaata
     3301 tgggagactt ctaggaccat ggggcgctgc aataggagga attggaggag cagtggtttg
     3361 tggatattta gcctataccg ctacatcata aaaatgaaag ctaaatttta tgaaggctat
     3421 attctttatt attctcttcg cttttcaaac ctatcttatt tatctatcca taagtatctc
     3481 tgataaaaaa caaaagacta ttgaattaac atcattgaat tgttttgtca tattatttct
     3541 aatctacgat aaattaattt ttctctttat tgcctatgtt tttttgataa tttttatatt
     3601 aaacttgttc cgtaactgaa aagtgacata ctatatgaat acaaaaatga tgtcacaatt
     3661 ttctgttatg gataatgaaa tgcttgcttg cgttgaaggt ggagatattg attggggaag
     3721 aaaaattagt tgtgcagcag gggttgcata tggcgcaatt gatgggtgtg caacaacggt
     3781 ttgacatttc tattgggacc atttgctata ggaataggtg taactggtgc tgcaggtgga
     3841 gctatacttg gaggtgtagc ctatgtagca acatgttggt ggtaattatg gattttaaaa
     3901 gttttattat tggtttagta gttggtatat ttggtcctta tatggatgac ttaattagaa
     3961 aaatattttc aaaatcttcc aaaaaggata cggatagtac tctctaaaaa ataaatttct
     4021 cccctgtatt tgctagctta atttacaggg gagtttcttt aatattgttt cgcctgtcaa
     4081 aatgatatgt gatagcagga tgaaaagtct acaaacaagt tggtatcaat acaatataaa
     4141 gaggaaagta tgtttttaat gcttactttt taaatttttt aacaattcaa gatgtttcga
     4201 tgacaattca agatttggat gaaaaatttt aaaaaacaat gatatactaa acttgtcaaa
     4261 gttgcaacgg gtgctgctac attatgttaa aaatcgctct tgattgataa gctggatttg
     4321 ttaggaaagg agtaaataat tatggataag aaaaagatag tttcgactat aatatgtata
     4381 gtatttcttg tagtgtcagt agataatttt tttagagact taaccccgtt actgttcatt
     4441 ttaaatatta ttggcctgtc ttgcttttca gtgctaacat acattaacat aaaagagata
     4501 ctcttaaata taagtaaatg atgatttggt tagtcctaga accaatcaac ttatgtttat
     4561 cggcttggca gattttatgt ttgtcatttg tttgtataga ggtatttcag aaacagaatt
     4621 ctatcaacaa ctaatcgctt atataggtgt attctctgct tgtttatcac gcttctgctc
     4681 atgtggggct tgaagtatta taaaaagtag ctttctatcc ttttctgaca ggatatttga
     4741 gtagaaggct ctattaaatt gttagtgaaa taaatgaatg gaggtattta atatgaaata
     4801 cagattattt tttgttattt tcttgagtag tgtgttggat attcttttag ggacattttt
     4861 acaaatctct atcgtatcta ttgggtggct tgttctttac agtggtttgt ttgaagtagg
     4921 agttttcctt cttgctaata aaggggtggc ggtaaaaatc aaggaagtag atattcgaaa
     4981 tcgctttaaa tttatttttg gaaaaacctt atggtttcaa attcttttgc tcatcttttt
     5041 gataatcaaa ctttatcttg gtttggatgc gaggttgatt ttattctatg gacatatttt
     5101 cattgtcttt aatgccttaa tgtatctatt atctagtagt caggttagcc ttaaaaaaac
     5161 aaactgtctt cttaatctta cagcagtaga gtctgacaag gtgagatcat agtagggagg
     5221 atttctatga aaaagtatca acttctattc aaaataagtg cagtcttctc ttacttattt
     5281 ttcgtatttg gtctttctca gctgacgctt atcgtccaaa attattggca attttcttcc
     5341 cagattggta atttcgtctg gattcaaaat atcttgagtt tactatttag cggagtcatg
     5401 atttggattc tggttaagac aggccatggt tatctctttc gcattccaag aaaaaaatgg
     5461 ctttggtatt cgattttgac agtattagtg ctagtgctcc agatctcttt taacgttcag
     5521 acagctaaac atgttcagtc aactgctgaa ggttgggctg tattgatcgg ttatagtggg
     5581 accaactttg ctgagctagg tatctatata actttgttct ttctgactcc acttatggaa
     5641 gagctaatct atagaggatt actgcaacac gcctttttta agcattcgag atttggcctt
     5701 gatttgcttc ttccgtcaat tttatttgct cttcctcatt tttcaagcct gcctagtttg
     5761 ttagatatct tcatctttgc aacatctggc atcatctttg ctagtttgac ccgctatacc
     5821 aagagcattt atccttccta tgcggtgcat gtgatcaata atattttcgc aacattacca
     5881 tttttgctga cttttttaca tagggtcttg gggtaaaaaa acaaaaggct tgcttttcag
     5941 ccatagagga gattatcatg tataaacact tatttttcct agattccaaa actttagatc
     6001 ggttgacacc ctatattcta gtcttggctt ctgacaccat tgcttttaat gtttttgtgc
     6061 taacctttgt atctgcggtg gtttttaatt tcctaaattc catgctagct ttaatggcta
     6121 tattcatagg ggctggctat gtggtcggat tttggttact aatactcaat gaaaatcaaa
     6181 gagcaaacta ggaaactagc cgcaggctgt acttgagtac ggcaaggcga cgttgacgtg
     6241 gtttgaattt gattttcgaa gagtataaaa tggtttgttt tggaaaggct agaactaaag
     6301 aatgacgcgt aggaagtctg tttggtgagg aggatagttt tatggagttt tttgatcccc
     6361 aattattcac cccaaatcta aaaaccatcc agaatccttg ccttagctta gatcctggat
     6421 ggtttctttt ttcacccaat gggtgttttt tactagacaa aaaagagttt cccctttatg
     6481 gtataagtgt agaaaaaaac acaaaaagaa aggaaactca catgaacagt ttaccaaatc
     6541 atcacttcca aaacaagtct ttttaccaac tatctttcga tggaggtcat ttaacccagt
     6601 atggtggtct tatctttttt caggaacttt tttcccagct gaaactaaaa gagcggattt
     6661 ctaagtattt agtaacgaat gaccaacgcc gctactgtcg ttattcggat tcagatatcc
     6721 ttgtccagtt cctctttcaa ctgttaacag gttatggaac ggactatgct tgtaaagaat
     6781 tgtcagctga tgcctacttt ccaaaatt
//
LOCUS       DAVLIK010000076         6426 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLIK010000076 DAVLIK010000000
VERSION     DAVLIK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.076"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            196..1962
                     /gene="patB"
                     /locus_tag="VXE87_001951"
     CDS             196..1962
                     /gene="patB"
                     /locus_tag="VXE87_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0843434.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2101..2790
                     /locus_tag="VXE87_001952"
     CDS             2101..2790
                     /locus_tag="VXE87_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0843435.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            2794..2973
                     /locus_tag="VXE87_001953"
     CDS             2794..2973
                     /locus_tag="VXE87_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843436.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            2960..4309
                     /locus_tag="VXE87_001954"
     CDS             2960..4309
                     /locus_tag="VXE87_001954"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0843437.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4433..5893
                     /locus_tag="VXE87_001955"
     CDS             4433..5893
                     /locus_tag="VXE87_001955"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0843438.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            5907..6338
                     /locus_tag="VXE87_001956"
     CDS             5907..6338
                     /locus_tag="VXE87_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0843439.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
BASE COUNT         2030 a         1221 c         1382 g         1793 t
ORIGIN      
        1 tttcattaca cgagataaaa cgtctatgcg ttatcaaact cattaccaat taaaacaaaa
       61 agctgtggtt agatcctttc ggaaattgtc aagcgattgg aggaaatgaa ctaatccaca
      121 gcggcttatt ccaagtatac cacttgggct ttggcagtag ctaactgcgc taaatataat
      181 ataaggagga gtaaaatgaa gacagttcaa tttttttggc attattttaa ggtctacaag
      241 ttctcatttg tagttgtcat cctgatgatt gttctggcga cttttgccca agccctcttt
      301 ccagtctttt ctggacaagc ggtgacgcag ctagccaatt tagttcaagc ttatcaaaat
      361 ggcaatccag aacttgtatg gcaaagccta tcaggaatca tggtcaatct tggcctgctg
      421 gttttggttc tatttatctc tagtgtaata tacatgtgtc tcatgacgcg cgtgattgca
      481 gaatcgacca acgagatgcg caaaggcctc tttggtaagc ttgctcagtt gacggtttct
      541 ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt ttaccagtga tttggataat
      601 atcctccaag cctttaacga aagcttgatt caggtcatga gcaatattgt tttatacatt
      661 ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg ctctcatcac cattgccagc
      721 accccattgg ctttccttat gctgattttc atcgtgaaaa tggcacgcaa atacaccaac
      781 ctccagcaga aagaggtagg gaagctcaac gcctatatgg atgagagcat ctcaggccaa
      841 aaagccgtga ttgtgcaagg aattcaagag gatatgatgg caggatttct tgaacaaaat
      901 gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct caggaattct tttccctgtc
      961 atgaatggga tgagcctgat taatacagcc atcgtcatct ttgctggttc ggctgtactt
     1021 ttgaatgata agtctattga aacaagtaca gccctaggtt tgattgttat gtttgcacaa
     1081 ttttcacagc agtactacca gcctattatc caagttgcag cgagttgggg aagccttcag
     1141 ttggccttta ctggagctga acgaattcag gaaatgtttg atgcagagga ggaaatccga
     1201 cctgaaaagg ctccaacctt cactaagttg caagaaagtg ttgaaatcag tcatatcgat
     1261 ttttcatact tgcctgataa acctattttg aaagatgtca gcatttctgc ccctaaaggc
     1321 cagatgacag cagttgttgg gccgacaggt tcaggaaaaa cgactattat gaacctcatc
     1381 aatcgctttt atgatgttga tgctggtggt atttattttg atggtaaaga cattcgtggc
     1441 tatgacttag atagtcttag aagcaaggtg ggaattgtat tgcaagattc ggtcttgttt
     1501 agcggaacga ttagagacaa tatccgattt ggtgtgccag atgctagtca ggaaatggtt
     1561 gaggtagcag caaaagcaac ccacattcac gactatatcg aaagtttgcc tgataagtac
     1621 gatactctta ttgatgatga ccagagcatc ttttcaacag ggcagaagca attgatttca
     1681 atcgctcgaa ccctgatgac agatccagaa gttctcattc tcgatgaagc aacttcaaac
     1741 gtagatacgg tgacagaaag caagattcag catgccatgg aggtggttgt agcaggtaga
     1801 actagtttcg tcattgccca ccgcttgaaa accattctca atgcagatca gattattgtc
     1861 cttaaagatg gagaagtcat tgaacgtggt aaccaccatg aacttttgaa gctaggtggc
     1921 ttttattcag aactctatca caatcaattt gttttcgaat aagaaagaag ttgtcctatg
     1981 tgggcagctt tttcttgtcc ataaaaaatg tttatcacag ccttaaaaaa aacatattag
     2041 acgaaagtca ttttgagtga tatgatagga ctatcgttag tattcgaaag gagaggcatc
     2101 atggctagaa cggttgtagg agttgctgca aatctatgtc ccgtagacgc agaaggcaaa
     2161 atcattcatt catctgtatc ttgtagattc gcagagatca ttcgtcaagt cggtggtctc
     2221 cctttagtca ttcctgttgg tgatgagtca gttgtacgtg attatgtgga aatgattgac
     2281 aaactcattt tgacaggagg ccaaaatgtt catcctcagt tttatggaga gaaaaagacc
     2341 gtcgaaagcg atgattacaa tctggtccgt gacgaatttg aattggcact cttgaaggaa
     2401 gcgcttcgtc agaataaacc aattatggca atctgtcgcg gtgtccaact tgtcaatgtt
     2461 gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact ggcaaggact acctttcggg
     2521 acatctcact ctattgaaac agtagaagga agcgtggtgg ctaagctatt tgggaaagaa
     2581 agtcaggtca actcagtcca tcgtcaaagc attaaagatt tggcacctaa tttccgtgta
     2641 actgctattg attcaagaga ccaaactatt gaagcgattg agtctatcga cgagcaccgc
     2701 attatcggtt tacagtggca tccagagttt ctggttaatg aagaagatgg caatttagaa
     2761 ttatttgagt atttattgaa tgaactgtaa cgattggaac atctggtcgt tctttctttt
     2821 attttttcaa aatttttaga atgtggcatt ttacgcaaac gtttgaattc tgataaaaat
     2881 tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta agcgttatga tagaaaagaa
     2941 gaaatattgg aggaagaaca tgtcacatat taaatttgat tattcaaaag ttttagacaa
     3001 atttgttgca ccacatgaag tggaatacat gcaatcacaa gtaacagcag cagatgaatt
     3061 gatccgtaaa ggaactggtg ctggtagcga cttcttggga tggttggacc ttcctgaaaa
     3121 atacgaccgc gaagaatttg accgcatctt gaaagctgct gagcaaatca agtcagacag
     3181 cgatgttttg gttgtgatcg gtattggtgg atcttacctt ggtgcaaaag cagcaatcga
     3241 cttcttgaat caccattttg ctaacttgca aacaaaagaa gaacgcaaag ctccacaaat
     3301 cctttacgca ggaaactcaa tctcatctac ttaccttgct gacttggtag agtatgttgc
     3361 agacaaagac ttctcagtaa acgtaatttc taaatcaggt acaacaactg aaccagcgat
     3421 tgctttccgt gtctttaaag aactcttggt taagaaatac ggtcaagaag aagctaacaa
     3481 acgtatctat gcaacaactg accgccaaaa gggtgctgtt aaggttgaag cagacgctaa
     3541 cggttgggga acatttgttg ttccagatga tatcggtgga cgcttctcag tattgacagc
     3601 cgttggtttg cttccaatcg cagcatcagg agctgacatc aaagctctta tggaaggtgc
     3661 gaatgcagct cgcaaagact acacttcaga caaaatctct gaaaacgaag cttaccaata
     3721 cgcagtcgtt cgtaacatcc tttatcgtaa aggctatgca actgagatct tggtaaacta
     3781 tgagccatca cttcaatact tctcagaatg gtggaaacaa ttggctggtg aatcagaagg
     3841 aaaagaccaa aaaggtatct acccaacttc agccaacttc tcaactgact tgcactcact
     3901 tggtcaattt atccaagaag gaactcgtat catgtttgaa acagttgtcc gtgttgacaa
     3961 acctcgtaaa aacgtgctta ttcctacttt ggaagaagac cttgacggac ttggttacct
     4021 tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact gacggtgttc ttcttgccca
     4081 cacagatggt gatgtaccaa acatgtatgt gactcttcca gagcaagacg ctttcactct
     4141 tggttacact atctacttct tcgaattggc aattgccctt tcaggttact tgaatgctat
     4201 caacccattt gaccaaccag gtgttgaagc ttataaacgt aacatgtttg cccttcttgg
     4261 aaaaccagga tttgaagaat tgagcaaaga acttaacgca cgtctataat agaagaaaag
     4321 agtggtttgc ccactctttt tactctcttt atccatagaa attggactca gccaagactt
     4381 gtgatataat atagaaagca aaaaggcaga cgcctagata ataggagaaa ctatgtcaaa
     4441 agatatccgc gtacgttacg caccaagtcc aacaggacta ctacacatcg gaaatgcccg
     4501 tacagcattg tttaactact tgtatgcgcg ccatcatggt ggaacatttc tcatccgtat
     4561 cgaagatact gaccgtaaac gccatgtcga ggatggtgaa cgttcacaac ttgaaaacct
     4621 tcgctggtta ggcatggatt gggatgaaag tccagaatca catgagaatt atcgccagtc
     4681 tgagcgtttg gacttgtatc aaaaatacat tgaccaacta ttagctgaag gaaaagccta
     4741 taaatcttac gttacagaag aagagttggc agctgaacgt gaacgtcaag aagtagctgg
     4801 cgaaacacca cgctacatca atgaatacct tggtatgagt gaagaagaaa aagcggctta
     4861 tatcgcagaa cgtgaagcag ctggtatcat accaacagtt cgtttggctg tcaatgagtc
     4921 aggtatctac aagtggcatg atatggtcaa aggtgatatc gaatttgaag gtggcaatat
     4981 cggcggtgac tgggttatcc aaaagaaaga cggttaccca acttacaact ttgccgttgt
     5041 tatcgatgac cacgatatgc aaatctctca tgttatccgt ggagatgacc atattgctaa
     5101 tacaccaaaa cagcttatgg tctatgaagc tcttggttgg gaagctccag agtttggtca
     5161 catgaccttg attatcaact ctgagactgg taagaagtta tctaaacgtg atactaatac
     5221 acttcaattt atcgaagatt accgaaagaa aggttacctt ccagaagcag tctttaactt
     5281 tattgctctt cttggttgga acccaggtgg tgaagatgag attttctctc gtgaagaact
     5341 cattaaactt tttgatgaaa accgcctcag caagtcacca gcagcctttg atcagaaaaa
     5401 attagactgg atgagcaatg attatatcaa gaatgcagac cttgaaacca tctttgaaat
     5461 ggcaaaacca ttcttagagg aagcaggccg tttgactgac aaggctgaaa aattagttga
     5521 gctctataaa ccacaaatga aatcagtaga tgagattatc ccattgacag atcttttctt
     5581 ctcagatttc ccagaattga cagaagcaga gcgcgaagtc atgacgggtg aaacagttcc
     5641 aacagttctt gaagcattca aagcaaaact tgaagcgatg acagatgatg aatttgtgac
     5701 agaaaatatc ttcccacaaa ttaaagcagt ccaaaaagaa acaggtatta aagggaaaaa
     5761 tcttttcatg cctattcgta tcgcagtttc aggcgaaatg catgggccag aattaccaga
     5821 tacaattttc ttgcttggac gtgaaaaatc aattcagcat atcgaaaaca ttctaaaaga
     5881 aatctctaaa taaagaggat acaataatgg acatctggga aaagatgtac gaagaagcac
     5941 agaaactata caatccacat gaagtatcag actttgttta tgccaatcat gttgtagctg
     6001 cagtagaagc aggagatgga caaatattta caggattctg tatggaggga acctgtggtg
     6061 ttttccatct ctgcgcagaa cgggcgaccc tcttcaatat gtaccaattt tcaggacaaa
     6121 ctaaggttaa gaaagtatta gcctttcgag acaaaccacc ttatggtgga agttcagcca
     6181 tgccttgcgg tgcttgtaga gaattccttt tagagcttaa tgctgaaaat aaagatgcag
     6241 aattcatgat ggactataat ataagaaaaa cagttaaagt cgcagaacta atcccttatt
     6301 ggtggggaga agaacgtgct tctaagttta atgagtgata gaagagtcag tataattctg
     6361 gctcttttta ctataagttg aaaaaataaa aaaaattaga aaaagtagtt gacaaaattt
     6421 gaaaag
//
LOCUS       DAVLIK010000077         6416 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLIK010000077 DAVLIK010000000
VERSION     DAVLIK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.077"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(93..389)
                     /locus_tag="VXE87_001957"
     CDS             complement(93..389)
                     /locus_tag="VXE87_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0843440.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(379..540)
                     /locus_tag="VXE87_001958"
     CDS             complement(379..540)
                     /locus_tag="VXE87_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0843441.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            610..1374
                     /locus_tag="VXE87_001959"
     CDS             610..1374
                     /locus_tag="VXE87_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0843442.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(1614..1766)
                     /locus_tag="VXE87_001960"
     CDS             complement(1614..1766)
                     /locus_tag="VXE87_001960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843443.1"
                     /translation="MKIKASIRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NISTAR"
     gene            1984..3363
                     /locus_tag="VXE87_001961"
     CDS             1984..3363
                     /locus_tag="VXE87_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0843444.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3377..4042
                     /locus_tag="VXE87_001962"
     CDS             3377..4042
                     /locus_tag="VXE87_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0843445.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4177..4251
                     /locus_tag="VXE87_001963"
                     /pseudo
     CDS             4177..4251
                     /locus_tag="VXE87_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4397..4936
                     /locus_tag="VXE87_001964"
     CDS             4397..4936
                     /locus_tag="VXE87_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0843446.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            5036..5413
                     /locus_tag="VXE87_001965"
     CDS             5036..5413
                     /locus_tag="VXE87_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0843447.1"
                     /translation="MIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLDLSQVSHPKMRE
                     YLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPKVFQAIRKTMLSRLTKH
                     SVLPDRKLSNVVYQITKSVYGFN"
     gene            5529..>6416
                     /gene="pavB"
                     /locus_tag="VXE87_001966"
     CDS             5529..>6416
                     /gene="pavB"
                     /locus_tag="VXE87_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0843448.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLV"
BASE COUNT         1733 a         1224 c         1485 g         1974 t
ORIGIN      
        1 gcctgcggct aacttcctag tttgcacttt aattttcatt gagtattact tcatcttctc
       61 atgaaattga gtttttgccc agctcctctt gattattcta cttgaccggg ccaagcattc
      121 ataccacctt ctacgttggt aacggtgagg ccttgggagc tgagaaattg gcaggtagat
      181 gcagagcgga ctcctccttg acaaatgaca tagtattcat ggtcaggttt gagttctttg
      241 tagccttgct ctaaggtact taatggaaga tttttggcac ctggtgcatg tcctgcttgg
      301 aattcatgtg cttcacggac atcgataagt tctagatttt cattttggta ttttccataa
      361 aagtcagcca tgctgatact agtttccata ttctactcct tctgggttaa ccattttgta
      421 tagtgaataa gcgccgtcaa ggttttgggc ggtaaatcct gcttgcttga ggataggctc
      481 tgcgatatag ctgcgcaaac cactgtggca gctgacgatg taggcttgtt ttttgtccag
      541 ttcatcagct tcctccttga cactttgtca gtttttgata caatagtaca aaattagagg
      601 aggcaggcta tgattcagaa acatgcgatt cctattttag agtttgatga caatcctcag
      661 gcggttatca tgcccaatca cgaggggctg gacttgcagt tgccaaagaa gtgtgtttat
      721 gcatttttag gtgaggagat tgaccgctat gcaagggaag taggggcgga ttgtgtcggc
      781 gaattcgttt ctgctaccaa gacctatcca gtctatgtca tcaactacaa gggtgaggag
      841 gtctgtctgg ctcaggctcc tgttggctcc gctccagcag cccagtttat ggattggttg
      901 attggctatg gtgtggagca gattatctct actgggacct gtggtgtcct agctgatata
      961 gaggaaaatg cctttctagt ccctgttcgc gctttgcgag atgagggagc cagttaccac
     1021 tatgtggcac cttgtcgtta tatggaaatg cagccagagg ctattgctgc tattgaggaa
     1081 gttttggaag acagagggat tccttatgaa gaagtcatga cctggacgac agacggtttt
     1141 taccgagaaa cggctgaaaa ggtggcttat cgtaaggaag aaggctgtgc tgttgtggag
     1201 atggagtgtt ctgctcttgc ggcagtagct caattgcgtg gggttctctg gggtgaattg
     1261 ttgttcacag cagattctct agcggacttg gaccagtacg acagtcgtga ctggggctcg
     1321 gaagctttta ataaggcgct agaactgagt ttagcaagtg ttcaccacct ttagttgtac
     1381 tggcaaagga tttgttttat cataaaatgt ctagctcata cttttcaaaa atatgtttaa
     1441 acgaggtcac cttcctcttg tcctaggcat gttgaggttg ggaaaaatct ttaaaatcag
     1501 aaaaacgtat catatcaggt gatgaaaact ttgatactat gcgttttatg ttggtaagat
     1561 ttagagtgag atgaaatgat actcttcgaa aatcttttca aaccaggtca gcttcacctt
     1621 gccgtagata tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgttttgag
     1681 ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgtgactagc
     1741 tttctaatcg atgccttgat tttcattgcc tataatcaaa aagagaaatt ttctcctgaa
     1801 aagcatatag agtagctggc gttaaaagct cctgtcttgc ttttttgacc tatagtcaca
     1861 tctatcaagt attgttcttg cctaagctat caataaaaag gtggcatttt ttaggcttgg
     1921 tgttagtgaa ttttgcctta tcctatctaa gtcatttcga gctttttatg gtacaatgga
     1981 aacatgttat tcaaattatc taaggaaaaa atagagctag gcttatctcg tttatcgcca
     2041 gcccgtcgta tttttttgag ttttgccttg gtcattttac taggctctct tcttttgagc
     2101 ttgccctttg tccaagttga aagctcacga gcgacttatt ttgatcatct tttcactgct
     2161 gtctctgcag tctgtgtgac aggtctctca acccttccag tagctcacac ctataatatc
     2221 tggggccaaa taatctgttt gctcttgatt cagatcggtg gtctagggct catgactttt
     2281 attggggttt tctatatcca gagcaagcaa aagcttagtc ttcgtagccg tgcaactatt
     2341 caggatagtt ttagttatgg agaaactcga tctttgagaa agtttgtcta ttctattttt
     2401 ctcacgacct ttttggttga gagcttggga gctattttgc ttagttttcg ccttattcct
     2461 caacttggct ggggacgtgg tctttttagt tccatttttc tagcgatctc agccttctgt
     2521 aatgccggtt ttgataattt agggagcacc agtttatttg cttttcagac cgatttactg
     2581 gtcaatctgg tgattgcagg cttgattatt acaggcggcc ttggttttat ggtctggttt
     2641 gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc tgcactttca tacgaagctt
     2701 gtactattat tgactatagg tttgttgtta tttggaacag caactactct ctttcttgag
     2761 tggaacaatg ctggaacgat tggcaatctc cctgttgccg ataaggtttt agttagcttt
     2821 tttcaaacag tgacgatgcg aacagctggc ttttctacga tagattatac tcaggctcat
     2881 cctgtgactc ttttgattta tatcttacag atgtttctag gtggggcacc tggaggaaca
     2941 gctgggggac tcaagattac gacatttttt gtcctcttgg tctttgcacg aagtgagctt
     3001 ctaggcttgc ctcatgccaa tgttgcgaga cgaacgatcg cgccgcgaac ggttcaaaaa
     3061 tcctttagtg tctttattat ctttttgatg agcttcttga taggattgat tctgctaggg
     3121 ataacagcca aaggcaatcc tccctttatc cacctcgtat ttgaaaccat ttcagctctt
     3181 agtacagttg gtgtaacggc aaatctgact cctgaccttg ggaaattggc tctcagtgtt
     3241 atcatgccac ttatgtttat gggacgaatt ggtcccttga ccttgtttgt tagcttggca
     3301 gattaccatc cagaaaagaa agatatgatt cactatatga aagcagatat tagtattggt
     3361 taagaaagga aagagcatgt cagatcgtac gattggaatt ttgggcttgg gaatttttgg
     3421 gagcagtgtc ctagctgccc tagccaagca ggatatgaat attatcgcta ttgatgacca
     3481 cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt ggagtgattg gtgacatcac
     3541 agatgaagaa ttattgagat cagcagggat tgatacctgc gataccgttg tagtcgcgac
     3601 aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac tgtaagagtt tgggggtacc
     3661 gactgttatt gctaaggtca aaagtcagac cgctaagaaa gtgctagaaa agattggagc
     3721 tgactcggtt atctcgccag agtatgaaat ggggcagtct ctagcacaga ccattctttt
     3781 ccataatagt gttgatgtct ttcagttgga taaaaatgtg tctatcgtgg agatgaaaat
     3841 tcctcagtct tgggcaggtc aaagtctgag taaattagac ctccgtggca aatacaatct
     3901 gaatattttg ggtttccgag agcaggaaaa ttccccattg gatgttgaat ttggaccaga
     3961 tgacctcttg aaagcagata cctatatttt ggcagtcatc aacaaccagt atttggatac
     4021 cctagtagca ttgaattcgt aaagagggat gacccctctt ttttgatgcc caagatggca
     4081 aatagagaca gaagcccctt gtcttctagt aaaagttctt caaaggctgg actttatggt
     4141 aaaatagaaa gaagtgacaa gagagagtaa tactcaatga aaatcaaaga tcaaactagg
     4201 aaactagcta cgggctgctc aaaacagtgt tttgaggttg tggatagaac tgacgaagtc
     4261 agctcaaaac actgttttga ggttgcagat agaactgacg aagtcagtaa catctatacg
     4321 gcaaggcgac gttgacgcgg tttgaagaga ttttcgaaga gtataagaaa aaatcagtcc
     4381 cctaaaggag cagattatga agttattgtc tatcgccatt tctagctata atgcagcagc
     4441 ctatcttcat tactgtgtgg agtcgctagt gattggtggt gagcaagttg ggattttgat
     4501 tatcaatgac gggtctcagg atcagactca ggaaatcgct gagtgtttag ctagcaagta
     4561 tcctaatatc gttagagcca tctatcagga aaataaaggc catggcggtg cggtcaatcg
     4621 tggcttggca gaggcttctg ggcgctattt taaagtagtt gacagtgatg actgggtgga
     4681 tcctcgtgcc tacttgaaaa ttcttgaaac cttgcaggaa cttgagagca aaggtcaaga
     4741 ggtggatgtc tttgtgacca attttgtcta tgaaaaggaa gggcagtctc gtaagaagag
     4801 tatgagttac gattcagtct tgcctgttcg gcagattttt ggctgggacc aggtcggaaa
     4861 tttctccaaa ggccagtata tcatgatgca ctcgctgatt tatcggacag atttgttgcg
     4921 tgctagccag ttctaactgc ctgaacatac tttttatgtc gataatctct ttgtctttac
     4981 gccccttcag caggtcaaga ccaggtacta tctgcctgtc gatttctatc gttatttgat
     5041 tgggcgtgag gaccagtctg tcaatgagca agtgatgatt aagtgcattg accagcaact
     5101 caaggtcaat cgactcttgg tagaccagct tgatttgtcc caagtgagtc atcctaaaat
     5161 gcgagaatat ctgctgaatc atattgaaat cacgacggtg atttccagta ccctgctcaa
     5221 ccgatctgaa acagcggagc atctggcaaa aaaacgccaa ttgtggacct atattcagca
     5281 ggaaaatcca aaagtctttc aggctattcg taagaccatg ttgagccgtt tgaccaaaca
     5341 ttctgtcttg ccagatcgca aactgtccaa tgtcgtctat caaatcacca aatctgttta
     5401 tggatttaat taatataagt gttttataag agggatttaa gaaaaatttt aactttttct
     5461 tagtcctttt taatttcagg agattatact agagtcatca aataaagaaa gactctaagg
     5521 agaatcctat gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca
     5581 gtgtcggtgt tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa
     5641 gttctgtacg tgccgatggg ctcaatccga ccccaggtca agtcttacct gaagagacat
     5701 cgggaacgaa agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga
     5761 aacctgaggg cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag
     5821 tgagcgagga aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc
     5881 aagaaaatcc agagctaaca gatgccttaa aagaaactgt agatacagct gatgtggatg
     5941 ggacacaagc aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa
     6001 atacaaaaga cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc
     6061 ctttcactgc cggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt
     6121 taactcgtct attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta
     6181 aaaatcctgc tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag
     6241 acttaaatgg caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta
     6301 atggtactca aacttataaa gctactgtta aagtttacgg aaataaagac ggtaaagctg
     6361 acttgactaa tctagttgct actaaaaatg tagacatcaa catcaatgga ttagtt
//
LOCUS       DAVLIK010000078         6071 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLIK010000078 DAVLIK010000000
VERSION     DAVLIK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.078"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            382..1577
                     /locus_tag="VXE87_001967"
                     /pseudo
     CDS             382..1577
                     /locus_tag="VXE87_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(1956..2741)
                     /locus_tag="VXE87_001968"
                     /pseudo
     CDS             complement(1956..2741)
                     /locus_tag="VXE87_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(2743..3562)
                     /locus_tag="VXE87_001969"
                     /pseudo
     CDS             complement(2743..3562)
                     /locus_tag="VXE87_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
     gene            complement(3564..4556)
                     /locus_tag="VXE87_001970"
     CDS             complement(3564..4556)
                     /locus_tag="VXE87_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0843449.1"
                     /translation="MKMITVEHLQKNFVKTIKEPGLKGAFRSFFHPKRQVFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQENRQGYVKDIGVV
                     FGQRTQLWWDLALQETYSVLKEIYDVPDAVFQKRMDFLNEVLDLKEFIQDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLG
                     DIEQLCDRIFMIDKGREIFDGTVNQLKKTFGKMKTLSFELHPGQDYIVSHFEGLSDIY
                     VTRQELSLDIQYDSSQYQTADIIQQTLSDFTIRDLKMTDANIEDIIRRFYRKEL"
     gene            complement(5573..6070)
                     /locus_tag="VXE87_001971"
     CDS             complement(5573..6070)
                     /locus_tag="VXE87_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HEV0843450.1"
                     /translation="MTEFPIEFFNKSDAGFQHMIKTYDQMINQKQSKLGYKKFFKLLL
                     SHPKDESLLFHCSMGKDRTGIASLFLLYILGVDMNDIFHDYLLSNKYLINVRKENIEY
                     VNNHSGNVILMHNLLSLSSAKEEYINRVLNVLDKEYGGILRYINTELGISSQEIEELK
                     DRYLF"
BASE COUNT         2150 a         1165 c          938 g         1818 t
ORIGIN      
        1 aagttactaa aaaaagattt tggaataaac tttttcatag cgataaaagc accgtacaag
       61 ctaggaaaat aataagtaat cgcccaatct gaccttctcc agaacttgat tattcgtcaa
      121 tcactacagt tgacaaacat actaagatta gtagtgagga aatctccaac gggagagagt
      181 actcattact ttttctttgt gttaaaatag tggtgtcttg ttaagtcata gagctctcta
      241 tggtgctaga cgtcgcttga caaactggca agaaacctgt tttaggaaga attttatcaa
      301 agtatgtggg atactagacg tcgagtattg gaaataaaat cactaaaaca aggagtcatt
      361 caagacaaag gggtaaacat gatgcggaca gttttcagaa tggatgtgag taaggcaagc
      421 tcagaagtcg ctattcttgt gaatggtgaa aaggttcatg gctataccat gcccaatgat
      481 gccatcggat ttagtcgtct tctagaggat ttgaaatagg taaatacacc tgagattatc
      541 ttcgaggcac aggggtctat tctcgtcttc aggcctttct ggaggacaat agctatgctt
      601 atatacggct aaatccttta aaactaagaa gcaactagac agtttgcgag tccgtaaaac
      661 caatcagatt gacgctgaaa agctagcttc gtcacaattc atccttaacc gcaaaccaac
      721 ttatgttcaa gaagaagtct atcaaaattt gcgtgacctc agtcgattct atcagaatct
      781 gacagaagac atcgttagga ctaagaatag cctgcacaag gtgcttcaaa ttgcctttcc
      841 agaaataaag aaccttctct ctactcctac aggggaacaa tattggaacc tcgtgaccat
      901 ctttccaacc aagcattgga ggctgaaatt atcagtagtt gagctaaaag aagccatcgt
      961 aattcaactt ctaaacggat ttctgagaac agagttggac gattggctga aaagttgagc
     1021 gagctggccg aacagtccta tcttgccatt tcaaaaacct ctcccatgac agaagaggtt
     1081 aagtatcatg cacaggaact gttgagactg acaaaccgca aggatcagga cttagcacaa
     1141 atgattgaat tggctgaacc attacctgaa tacgagattc tgctctctat tcctggtatc
     1201 gcagaaacaa cagctacaag cattattggc gaattggaga cattcgtcgc tttcagtctg
     1261 ccaaccaaat caatgccttt atcagtattg acctcagaca ctatgaatct ggcaatttcc
     1321 tagctcaaga acatatcacc aagcgtggaa atccttacgc gagaaaaatt ctctataagt
     1381 gcgtccacaa tattgcttca gctagtcata ccaatccttg tcatatcgcg gacttttatg
     1441 agaaacgaaa aagacaatcg cagacgactt caaccaagcc atatacgatt gtctctatac
     1501 atcgcctcat ccggacaatg tattacctca taacgcataa caaactttac gactacactt
     1561 taacccaaag tcattaaagt catctatgtc ctatcattgt aacaccttat tttttaatac
     1621 cagataagtg tcttttaagt gtgcccaaat ttcaaaaaac agctcgcaat tatcttctaa
     1681 acattccttt gatactcatt cagaaaacct tttgagctag aatatcgtat gtcccttaac
     1741 aaatggtatg tataaaagag ctaaaaaacc actcatgata tgaacgagtg gttatgactg
     1801 aaatattaca tacctttgta tcatttttgc acaatggtca aatttcttgt ttgaaaaact
     1861 acagtaagcc taatcaaagc tctcaatgta tcattaaaac ttccttccaa agaataggaa
     1921 gttctatcaa aattcttaat tagattttac ttcttctaag accctgcgct ctcatatgca
     1981 tccaaacctt tgttccataa ttttaatgat aaggtaaaaa atattaatga gataaggatc
     2041 aatccaccaa tattgaacaa tccatccttg tctttcaaga aatagctagc tgggtaatag
     2101 gctgtaaaag caaaaggaat gataaaacta atcaaccaac gtaaaaacga atggtaaatc
     2161 gcaatcgggt attttgcaaa atcattaaac atgtaaaaaa tataaattat tgccccagat
     2221 tgtttagtcc aaaaagcaat actagctgtt acaattttta aagaggtata aattaaggtt
     2281 gcaaagggaa tactgattaa aaagagaaaa acctttgccc aagtccaagt aagactagtt
     2341 attgtcatta acagcaataa gacgcctact aacaattctc caagagcatc aatttgaaac
     2401 gtttctacta aaatatgaaa caaagggcta atgggtctag tcaaatactt atcaaattct
     2461 cctttacgaa ttaaatgttg tcctaaagct cacagattat caaaaaagag atggtcaatt
     2521 cccttaggaa tgagagaaaa accataaata aaagcaacct gatgaaaact ccagccatca
     2581 agtaagggaa tatgttgaaa caaaatattt agaaacagca tgtttaaccc ttgtgtcaaa
     2641 aagacaccca caacaccaac taaaaaatca gccttatact ccataatctg tttaagatat
     2701 tgtcggataa aaatcaggtg catgcgttga tatttcttca ttctaacctc cttgaatagt
     2761 tatataattc tgtacgcact tccaaatcag ttgggataag gcaatcataa taaacagcca
     2821 gaataattgt agcgagagcg cctgaatcat ttgactcatg ctatactttt ctataataac
     2881 catcaccggg gtatagatta aagaagaaaa tggcaaaaaa gataatagtt cggcaataat
     2941 ttttggaaaa aatgtcagag gaaccaaact tccagataaa aaggcaacta aagaattttt
     3001 caaaagattt gatccccata agtttttaaa cacaaaagct gaaaaaccaa agcaaatatt
     3061 gaaaaaaaaa attaatcaaa aaagctaaga ttaagctaag aaggtaaact gtggttatta
     3121 aaacaatttg taagaaggac tcacctgata agagctttag acctgcaatc agaattacaa
     3181 atggtagacc aacactaaca aaaactagcc atctagaccc aatttctgtg aaaagataag
     3241 acattgcaaa atgaactgga cgaagcagtc gcataataat agagccatcc tttacttccc
     3301 atccaatcat aaaagaacta tctgattttg tcagtagatt cgtcacaaaa ctcatgatga
     3361 tatataaggt catatcagat aaagtaaaac cttgaatgag agactggtga gatgaatcaa
     3421 acacagcttt ccacaagtaa aatgctacaa aggcccccat cacatcccca atgcgataaa
     3481 gaaaaaaatt gacacgatac gtgattaatt cttggattcc agcgctaaca aaaggcttat
     3541 agcgtttcca taatttagtc atcctaaagc tcctttcgat agaagcgacg aataatatct
     3601 tcaatattcg catccgtcat ctttaaatca cggatcgtaa aatcagacaa agtttgttga
     3661 ataatgtcag ccgtttgata ctgcgagctg tcgtactgaa tatcaagtga caattcctgt
     3721 ctcgtcacat agatatcaga aagtccttca aaatgagaga caatataatc ctgcccagga
     3781 tgtagttcaa aagagagagt cttcatcttc ccgaaagtct ttttcagttg attcacagtt
     3841 ccatcaaaga tttctcggcc cttatcaatc ataaaaatac gatcacataa ctgttcaata
     3901 tcacctaaat cgtgggtcgt taaaagtatg gtcgtctctt cttcttgatt aatctgtgta
     3961 atggcacgtc gaatattatc cttgaccgaa acatctaaac caatagtagg ctcatctagg
     4021 aaaagaactt tcggattatg caataaggag gccgcaatat ccgccctcat acgttgacct
     4081 agagatagag ttctgacagg atcttgaata aattccttca aatctaaaac ttcatttaga
     4141 aaatccatgc gtttttgaaa gaccgcatca ggaacatcat aaatttcctt taaaaccgag
     4201 taagtctcct gcaaagccaa atcccaccaa agttgagttc gctgcccaaa aactacacca
     4261 atatctttaa catagccttg acggttctct tgaggaatct ttccattgat acgacaaaaa
     4321 cctgatgttg gtttcaaaat ccccgtcaac atcttgatag ttgttgattt ccccgctcca
     4381 tttgcgccaa taaagcctaa aatttgtcct ttgggcacct caaatgataa atctttaaca
     4441 gcttcaaaga cttgtctctt gggatgaaaa aaagagcgaa aagctccctt taagccaggt
     4501 tcctttattg ttttcacaaa atttttctga agatgctcta ctgttatcat ttttataaat
     4561 cactcctttc gtttcactca agttataata tcaacaaaaa ttgtagcata ctacagtaaa
     4621 gttaagaaaa tttaccatca ttacaaacca tatgaaaaaa gctactaaaa ctatgccatc
     4681 ttgtatttta tctgtaagta agctaaatta ctcaagtaca aagaattatg acgaagaaca
     4741 tataaattta taattggata aactatagat ttcagcaaac gaagttatcc caatataaaa
     4801 atactttaat aactgaagat attgacagga agatattaaa ttcctcatta ctatccttta
     4861 ctatgcagta taattttaat atcatttacc tacttccaag atgctgaaaa atactaagtc
     4921 acactattat gatgttatta tttccatttt tattttaaca gatgagtcaa ttctttcaac
     4981 taccccctcc cttataacta tattcatgaa gtattcttga taataaacct catttaactt
     5041 ctcaaagtag tcagcttctg caactgctat tatctcataa cagattgatt tggtttcaat
     5101 aaatggaagc tagaagcctt gtcagctacc ctgcacagtt ggtgtttttt catttttctc
     5161 ttcaaaaaaa ttggtcggaa gttataataa aaaggtgatg tgtttgtggt gagttgaatt
     5221 aagagacaaa ctcactttgt cttaactttt aaattgccta acaaaaatac ggagattatt
     5281 ctctaagctt taactgcaac attatgtctc tacaaccaac gataagtcca gaaatctacc
     5341 caaataacca aacaacctac atttgttgaa ctttgatgac aagtaggaaa ttttacattt
     5401 gataaacact attttgtacg cattttgcac ataatttaac gtgctttcca tcaatttagt
     5461 taaggactta catagaaaac aatccgtttt tgcttatgtt aaattagtag aattagacaa
     5521 aaacaaaacc gccgttcgca ctgttatata ttcattttta gtacttacta ttctaaaaaa
     5581 gatatctatc tttcaattcc tcaatttctt gactacttat tcctagttct gtattaatat
     5641 atctaagtat tcctccatat tctttatcaa ggacattcaa tactcgatta atatattctt
     5701 cttttgctga actgagtgaa agtaaattat gcatcaatat tacattccca ctatggttat
     5761 ttacatattc aatattttct tttctcacat ttattaaata cttgttagat agtaagtaat
     5821 catgaaaaat atcgttcata tctactccca atatataaag caagaacaag ctagctattc
     5881 ctgttcgatc cttccccatt gaacaatgaa acaaaagaga ttcatctttt ggatgactta
     5941 gtaataattt aaagaatttc ttgtaaccaa gtttactctg tttttgattg atcatttgat
     6001 cataagtttt tatcatatgt tgaaaacctg catctgattt gttaaaaaat tctattggga
     6061 attctgtcaa c
//
LOCUS       DAVLIK010000079         6039 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLIK010000079 DAVLIK010000000
VERSION     DAVLIK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.079"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            285..1730
                     /gene="cps4A"
                     /locus_tag="VXE87_001972"
     CDS             285..1730
                     /gene="cps4A"
                     /locus_tag="VXE87_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV0843451.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIIDSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1732..2463
                     /locus_tag="VXE87_001973"
     CDS             1732..2463
                     /locus_tag="VXE87_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV0843452.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLIESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKHVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            2472..3164
                     /gene="cpsC"
                     /locus_tag="VXE87_001974"
     CDS             2472..3164
                     /gene="cpsC"
                     /locus_tag="VXE87_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV0843453.1"
                     /translation="MKEQNTLEIDVLQLSRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRDQGEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGMSGTSVIVFLLEFLNTRVKRPEDIENTLQMT
                     LLGVVPNLSKLK"
     gene            3174..3857
                     /gene="cps4D"
                     /locus_tag="VXE87_001975"
     CDS             3174..3857
                     /gene="cps4D"
                     /locus_tag="VXE87_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4D"
                     /protein_id="HEV0843454.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SYGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPVGIVI
                     DAVIITQKCDASILVTATGEANKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     ASYGNYGKK"
     gene            3873..5240
                     /locus_tag="VXE87_001976"
     CDS             3873..5240
                     /locus_tag="VXE87_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0843455.1"
                     /translation="MDKKGLEIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNKFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNPKNSKKILLLTVTENIEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVDLPGESYDIGEIISKFETMG
                     IDVTVNLNAFNKNLGRNKQIHEIVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     RGGMFKMDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RNGAK"
     gene            5244..5693
                     /locus_tag="VXE87_001977"
     CDS             5244..5693
                     /locus_tag="VXE87_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--LPS N-acetylglucosamine
                     transferase"
                     /protein_id="HEV0843456.1"
                     /translation="MKVCLVGSSGGHLTHLYLLKPFWKDRERFWVTFDKEDARSILEN
                     EIFYPCYYPTNRNLKNLIKNTILAFKILRKERPDIIVSSGAAVAVPFFYLGKIFGAKT
                     VYIEVFDRIDAPTMTGKLVYPVTDRFIVQWEEMKKVYPKAINLGGIF"
     gene            5693..>6039
                     /locus_tag="VXE87_001978"
     CDS             5693..>6039
                     /locus_tag="VXE87_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug MFS transporter"
                     /protein_id="HEV0843457.1"
                     /translation="MIFVTVGTHEQQFNRLIKEVDRLKGEGFIQDDVFIQTGYSNYVP
                     KFCKWEKVISYEKMNQLIKESDIIITHGGPATFMAVIAKGKNPIIVPRLKKFGEHVND
                     HQMQFVKITKEIY"
BASE COUNT         1986 a          892 c         1233 g         1928 t
ORIGIN      
        1 taggtgcttt aaactattaa aattcttaag aaataaggct actttttctg ggtcttgttc
       61 ataattagat tgaaactaga atagtacact tctgcttcta aaacattgtt agaaatcgat
      121 ttgactgtcc tgatcgattt gtcatgttct tatttcattt tactatattt ttgtttcgcg
      181 ggaagtctac taagatactt aaagatgcag atagtaaaaa aaatgtagac attaccgtaa
      241 aaaagtgata taattgtacg atgttcaagg tataggtgtt aatcatgagt agacgtttta
      301 aaaaatcacg ttcacagaaa gtgaagcgaa gtgttaatat cgttttgctg actatttatt
      361 tattgttagt ttgtttttta ttgttcttaa tctttaagta caatatcctt gcttttagat
      421 atcttaacct agtggtaact gcgttagtcc tactagttgc cttggtaggg ctactcttga
      481 ttatctataa aaaagctgaa aagtttacta tttttctgtt ggtgttctct atccttgtca
      541 gctctgtgtc gctctttgca gtacagcagt ttgttggact gaccaatcgt ttaaatgcga
      601 cttctaatta ctcagaatat tcaatcagtg tcgctgtttt agcagatagt gatatcgaaa
      661 atgttacgca actgacgagt gtgacagcac cgactgggac tgataatgaa aatattcaaa
      721 aactactagc tgatattaag tcaagtcaga ataccgattt gacggtcgac cagagttcgt
      781 cttacttggc agcttacaag agtttgattg caggggagac taaggccatt gtcttaaata
      841 gtgtctttga aaatatcatc gagtcagagt atccagacta cgcatcgaag ataaaaaaga
      901 tttataccaa gggattcact aaaaaagtag aagctcctaa gacgtctaag aatcagtctt
      961 tcaatatcta tgttagtgga attgacacct atggtcctat tagttcggtg tcgcgatcag
     1021 atgtcaatat cctgatgact gtcaatcgag ataccaagaa aatcctcttg accacaacgc
     1081 cacgtgatgc ctatgtacca atagcagatg gtggaaataa tcaaaaagat aaattaaccc
     1141 atgcgggcat ttatggagtt gattcgtcca ttcacacctt agaaaatctc tatggagtgg
     1201 atatcaatta ctatgtgcga ttgaacttca cttctttctt gaaaatgatt gacttattgg
     1261 gaggggtaga tgttcataat gatcaagagt tttcagctct acatgggaag ttccatttcc
     1321 cagtagggaa tgtccatcta gactctgagc aggctctagg ttttgtacgt gaacgctact
     1381 cactagccga tggagaccgt gaccgtggtc gcaaccaaca aaaggtgatt gtggctatcc
     1441 ttcaaaaatt aacgtcaacc gaagcactga aaaattatag tacgatcatt gatagcttgc
     1501 aagattctat ccaaacaaat atgccacttg agactatgat aaatttggtc aatgctcagt
     1561 tagaaagtgg agggaattat aaagtaaatt ctcaagattt aaaaggtaca ggtcggacgg
     1621 atcttccttc ttatgcaatg ccagacagta acctctatgt gatggaaata gatgatagta
     1681 gtttagctgt agttaaagca gctatacagg atgtgatgga gggtagatga aatgatagac
     1741 atccattcgc atatcgtttt tgatgtagat gacggtccca agtcaagaga ggaaagcaag
     1801 gctctcttga tagaatccta caggcagggg gtgcgaacca ttgtctctac ctctcaccgt
     1861 cgcaagggca tgtttgaaac tccggaagag aagatagcag aaaactttct tcaggttcgg
     1921 gaaattgcaa aagaagtagc agatgattta gtcattgctt atggcgcaga gatatactat
     1981 actctggatg ctctagaaaa gctagaaaaa aaagaaattc ctacccttaa tgatagtcgt
     2041 tatgccttga ttgagtttag catgcatact tcctatcgtc agattcatac gggattgagc
     2101 aatattttga tgttgggaat cacgccagta attgctcata ttgaacgtta tgatgcttta
     2161 gagaataacg aaaaacatgt tcgtgaactg attgatatgg ggtgctatac tcagataaat
     2221 agttatcatg tttcaaaacc taagttcttt ggtgaaaaat ataaattcat gaaaaagaga
     2281 gctcggtatt ttttggaacg tgatttagtt catgtagttg caagtgacat gcacaattta
     2341 gacagtagac ctccatatat gcaacaggca tatgatatca ttgctaagaa atatggagcg
     2401 aaaaaagcga aagaactttt tgtagataat cccagaaaaa ttataatgga tcaattaatt
     2461 taggagaaaa tatgaaggaa caaaacactt tggaaatcga tgtattgcaa ctatccagag
     2521 ctttatggaa aagaaagtta gtcattttat tagtggcaat tataacttct tcagttgctt
     2581 ttgcctacag tacttttgtt atcaaacctg agtttactag tacgactcgg atttatgtag
     2641 ttaaccgtga tcagggagag aagtctggtt taaccaatca agacttgcag gcaggatcat
     2701 acttggttaa agactatcgt gaaattatcc tatcgcagga tgttttggag gaagttgttt
     2761 ctgatttgaa actagatttg acgccaaaag gtttggctaa taaaattaaa gtaacagtac
     2821 cagttgatac ccgtattgtc tctgtttcag ttaatgatcg agttcctgaa gaggcaagcc
     2881 gtatcgctaa ctctttgaga gaagtagctg ctcaaaaaat tatcagtatt actcgtgttt
     2941 ctgatgtgac aacactggag gaggcaagac cggcgatatc accgtcttcg ccaaatatta
     3001 aacgcaatac actaattggt tttttggcag ggatgagtgg aactagtgtt atagtttttc
     3061 ttcttgaatt tttgaacact cgtgtgaaac gtccggaaga tatcgaaaat acactgcaga
     3121 tgacactttt gggagttgta ccaaacttga gtaagttgaa ataggagaga ggaatgccga
     3181 cattagaaat agcacaaaaa aaactggagt tcattaagaa ggcagaagaa tattacaatg
     3241 ccttgtgtac aaatatacag ttgagcggag ataaactaaa agtaatttcc gttacttctg
     3301 ttaaccctgg ggaaggaaaa acaactactt ccgtaaatat agcaaggtcg tttgcgcgtg
     3361 caggctataa aactcttttg atcgatggcg atactcgaaa ttcagttata tcaggagttt
     3421 ttaaatcgcg tgaaaaaatt acagggctaa cagaattttt atctgggaca gctgatttat
     3481 cttacggttt atgtgataca aatattgaaa atttatttgt agttcaatcg ggatctgtat
     3541 caccaaaccc tacagccttg ttacaaagta aaaattttaa tgatatgatt gaaacattgc
     3601 gtaaatattt tgattatatc attgttgata caccacctgt tggaattgtt attgatgcgg
     3661 taattatcac tcaaaagtgt gatgcgtcca tcttggtaac agcaacaggt gaggcgaata
     3721 aacgtgatgt ccaaaaagcg aaacaacaat tagaacaaac agggaaactg ttcctaggag
     3781 ttgttttaaa taaattggat atctcggttg ataagtatgg agtttacgct tcctatggaa
     3841 attatggtaa aaaataactt aggaaagatt ttatggataa aaaaggattg gaaatttttc
     3901 tggcagtatt acagagtatt attgtcattt tattggttta ttttcttagc tttgttagag
     3961 agacagaact tgaacgttct tcgatggtta tactatacct tctccacttt tttgtattct
     4021 attttagttc ctatggtaac aaatttttta aaagagggta cctagttgag tttaatagta
     4081 ctataagata tatttttttc tttgcaatag ctataagtgt attaaacttt tttatagcgg
     4141 aacggtttag tatctctaga agaggaatgg tatacttctt aactttagaa ggaatatcct
     4201 tatacttgtt aaatttctta gtaaagaaat attggaagca tgtgtttttt aatccaaaaa
     4261 atagcaagaa aattttactg ttaacagtaa cggaaaatat agaaaaagtt cttgataaat
     4321 tgctagaatc tgatgaactt tcatggaaac tggtagcagt aagtgttttg gataaatctg
     4381 attttcaaca tgataaaata cctgtaattg aaaaggaaaa aattattgaa tttgcaacgc
     4441 atgaagttgt ggatgaggtg tttgtcgatc ttccaggaga gagctatgat attggagaaa
     4501 ttatctctaa gtttgagaca atggggatag atgtaactgt aaatcttaat gcatttaata
     4561 agaatttggg tcgtaataaa caaattcatg agatagtagg attgaatgta gtcactttct
     4621 ctacaaattt ttataaaact agtcatgtga tttcaaagag aattctcgat atttgtggtg
     4681 ccactattgg ccttattctt tttgctatag ctagtctagt tttagttcca ttgattcgta
     4741 aagatggcgg accagctatt tttgctcaaa ctcgtatagg gaaaaatggt cgacatttta
     4801 ccttttataa attccgttcg atgcggatcg atgctgaagc tatcaaagaa cagttgatgg
     4861 atcaaaatac gatgcgaggt ggtatgttta agatggacaa tgatcctcgt gttacaaaaa
     4921 ttggtcgctt tattcgtaaa accagtttag atgagttacc ccagttttgg aatgtcttta
     4981 taggagatat gagtttggtg ggaacacgtc cacctacagt agacgagtat gatcagtata
     5041 ctccagaaca gaaacgtcga ctcagcttta aacctggtat tacaggttta tggcaggtta
     5101 gcggccgtag taaaataacc gattttgacg atgttgtaaa attagatgtg gcttatattg
     5161 ataattggac aatctggaaa gatattgaaa ttttgcttaa aactgttaaa gttgtattta
     5221 tgagaaatgg agcgaagtaa gggatgaaag tatgtctagt tggatctagt ggaggtcatt
     5281 taactcattt gtatttatta aaacctttct ggaaagatag agaaagattt tgggtgactt
     5341 ttgataaaga agatgcaaga agtattttag aaaatgaaat attttatcca tgttattatc
     5401 ctactaatcg taatctaaaa aatcttatta aaaatacgat tcttgctttc aaaattttga
     5461 gaaaggaacg ccctgatatt atcgtctcat caggggcagc tgtagcagtt cctttctttt
     5521 atctagggaa aatatttggt gctaagacag tctatataga agtatttgat agaattgatg
     5581 ctccgacaat gactgggaaa cttgtttatc cagtaactga caggtttatt gtacaatggg
     5641 aagaaatgaa aaaagtatat ccgaaagcaa tcaatctcgg agggattttc taatgatttt
     5701 tgtgacagta ggtactcatg aacaacagtt taatcgactt ataaaagagg ttgatagatt
     5761 aaaaggtgag ggatttattc aggatgatgt ttttattcaa acaggatact ctaattatgt
     5821 tccaaaattt tgtaaatggg aaaaagtaat atcttatgaa aaaatgaatc aattgattaa
     5881 ggaatcagat attatcatta cccatggcgg tccagctacg tttatggcag ttattgctaa
     5941 aggtaaaaat ccaataattg ttccgcggct aaaaaaattt ggtgagcatg taaatgatca
     6001 ccagatgcaa tttgtaaaaa taacgaaaga aatatacaa
//
LOCUS       DAVLIK010000080         6026 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLIK010000080 DAVLIK010000000
VERSION     DAVLIK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.080"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            160..468
                     /locus_tag="VXE87_001979"
                     /pseudo
     CDS             160..468
                     /locus_tag="VXE87_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            632..1291
                     /locus_tag="VXE87_001980"
     CDS             632..1291
                     /locus_tag="VXE87_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0843458.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1316..2383
                     /locus_tag="VXE87_001981"
     CDS             1316..2383
                     /locus_tag="VXE87_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0843459.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            2487..3497
                     /locus_tag="VXE87_001982"
     CDS             2487..3497
                     /locus_tag="VXE87_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843460.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFIIPSDVL
                     QF"
     gene            3509..5200
                     /locus_tag="VXE87_001983"
     CDS             3509..5200
                     /locus_tag="VXE87_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0843461.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5203..5913
                     /locus_tag="VXE87_001984"
     CDS             5203..5913
                     /locus_tag="VXE87_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0843462.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2019 a          835 c         1154 g         2018 t
ORIGIN      
        1 tactatatta tcgcttacca atatttgcta aactttcaga aaaaaagttg gagtatatga
       61 tgctaggtga ctgcgtcatg ttagtaaacg aaatggaaat aactgatcat agagtagata
      121 acttatttga aaaagggaaa aatgagataa aagattcaag tagtagattt agcaatagga
      181 catataaaag ctttagaaaa agtatctgaa aaaacagatg tttatatcta taacctaggc
      241 tcgggagaag gcactagtgt attacaactt gtaaatacat ttgaaagtgt taataagatc
      301 cctattcctt ataaaatagt tccaagacgt tcaggagacg ttgcaactta ttatgcaaat
      361 gcagacaaag catataagga attaaattgg aggacaacaa aatcgattga agacatgtgt
      421 agagatacat ggaattggca atcaaaaaat cccaatggct ataattgatg atactgtcta
      481 tatgagtgct gtattttgga aaaattactt aaccttttaa tgaaagataa attaaaaaaa
      541 atgtttgaca gcgcttgaca aaggaaacgg tttcattgta taatgtaaac acaatgacac
      601 cgatgtcaaa tataaaaaag aaggtcttta tatgaaaaac ttaacaaaaa ttaagttcaa
      661 agaaaatggg gaatttaatc atttccctgg gaatacagtt gtagcaaatc tttatactaa
      721 acaagatttg atggaagttg ttgatattat tcaatcacgt tatagagaat taccatttat
      781 cgataagttt actttaactc caaggaattc tattcacatg actgtaattg aattgttgtg
      841 ccatgaaaat cgtgaaacgg agttttggag cagtaatctt cctctagata cacctttaca
      901 ggaaatacat gattactttg ctaaacaact tgaaattttt ccattgttgg atgaagaaat
      961 tcatatgcgt ataactgaaa tgggaaaaca aaacatacta gttgaacctg cagatgaagc
     1021 ttctgcaaag agattagaag aaattcgtac ttatgtctca gaaaaagcag gtgtttgttt
     1081 ccctaatcat gatagatatc aattccatat ttcaattggg tatcttcgga ttcctctaac
     1141 cgaagaggag gaagaagagt ttactaaagt cagagcagaa ttaactgaaa ttttattaga
     1201 gaagattcca actattactg taaaccgtat tgactatact gtatttgaag atatgagaca
     1261 atttgttcca tatcacgaaa aatttaaata aaataataaa aaaggagaac ttatcatgaa
     1321 aaaaatgaaa gtttggtcta ctgtacttgc aacgggagtt gctcttacta cacttgctgc
     1381 ttgctctgga ggttcaaatt ctacgactgc ttcttcatct gaagaaaaag ctgataaaag
     1441 tcaagaatta gttatctatt cgaactcagt ctcaaatggt cgtggtgatt ggttaactgc
     1501 taaagcaaaa gaagctggtt ttaatataaa aatggttgat atcgctggcg ctcaattagc
     1561 agaccgtgtt attgctgaga agaataatgc agttgcagat atggtatttg gaattggtgc
     1621 tgttgattca aataaaatta gagatcaaaa attactagta cagtacaagc ctaaatggtt
     1681 agataaaatt gatcaatctt tatcagataa agataattat tataatcctg tgattgttca
     1741 accattagtt ttaattgggg cgcctgatgt aaaagaaatg cctaaagatt ggactgaatt
     1801 aggtagtaag tataaaggta aatattcaat ttatggtctt caaggtggta caggacgggc
     1861 aattctagca agtatcttag ttcgttacct tgatgaaaaa ggagatttag gcgtatcaga
     1921 aaaaggatgg gaagttgcaa aagaatactt tgcaaatgcc tatactcttc aaaaaggtga
     1981 aagctcagtt gttaaagcgt tagataaaga aagcccaatt caatacggta tgatctgggg
     2041 ttctggagcg ttaattggac aaaaagaaca aaatgttgaa ttcaaagtta tgactcctga
     2101 gattggtgta ccatttgtaa ctgaacaaac tatggtttta agcactagta aaaaacaagc
     2161 gttagctaaa gaatttattg attggtttgg tcaatcagaa attcaagtag aatatagtaa
     2221 aaaatttgga tctattcctg ccaataaaga tgccctaaaa gagttacctg aagatacgaa
     2281 aaaatttgtt gatcaagtga aaccacaaaa tattgactgg gaagctgttg gaaagcattt
     2341 ggatgaatgg gtagaaaaag ctgaattaga atacgtaaaa taagaaataa gagttatttt
     2401 ttatgtccaa gtctctctat tatttctaaa tttaaggaag aaataaagag aggcttttgg
     2461 ttttagtaat agagggagtt agtgagatga ttaaatttga taatattcaa attaaatatg
     2521 gtgattttgt tgcaattgat aatctgaatt tagatataca tgaaggggaa ttctttacat
     2581 ttcttgggcc ttcaggatgt ggtaaatcaa ctactttgag agcattggta ggttttttag
     2641 atccatcatc aggaagtatt gaagttaatg gaacagatgt cactcatttg gaacctgaaa
     2701 agcgtggaat tggtattgta tttcaatctt atgcgctatt tccaactatg actgtttttg
     2761 ataatattgc atttggttta aaagttaaga aggtagctcc agatgttatt aaagctaaag
     2821 tatcagcagt ggcagcaaaa attaagatct ctgatcaaca gttacagcgt aatgtatcag
     2881 aattatctgg gggtcaacaa caaagggtag cattggctcg tgctctggtt cttgaaccta
     2941 aaattctttg tctagatgaa ccattgtcaa accttgacgc aaaattacgt gtagatttga
     3001 gaaaagagtt gaaaagactt caaaaagagt taggtattac tactttatat gttactcatg
     3061 atcaagagga agccttgact ttatctgata gaattgcagt ctttaacaat ggatacatcg
     3121 aacaggtcgg tacaccagta gagatttatc ataattctca aactgaattt gtatgtgatt
     3181 ttattggaga tattaatgtt ttgaccgatg aaacagtcca cgaagtatta ttgaaaaata
     3241 caagcgtttt cttagaggat aaaaaaggat acattcgatt agagaaagtt cgattcaatc
     3301 gtgaaactga acaagatttt attctaaaag ggacaattat tgatgttgag ttttctggag
     3361 ttacaattca ctatacaata aaagtttctg aaagtcagat tcttaatgta acaagtattg
     3421 atagtcaggc tgctattaga tctgtcggag aaagtgtgga attatttatc ataccatcag
     3481 acgttctgca attttaagga ggtgcagtat gcgtcataaa ttaaatttaa aagattggct
     3541 tattcgttta gggttaatct ggttcttagt aacatttatt atttatccaa actttgatct
     3601 agtagtgaat gtatttgtaa aaggaggaga attttccctt gatgctgtac atcgtgttct
     3661 aaaatctcag agggcacttc agagtattat gaacagtttt aagttagcat tttcactcat
     3721 tattacagtt aatgtcgtag gtattctttg tgttctattt acagagtact ttgatattaa
     3781 aggtgctaaa attttaaaat taggttatat gacctcttta atttatggag gagtggtttt
     3841 agcgactgga tataaatttg tctatggtcc ttatggattg attacaaaat ttttacaaaa
     3901 tgttatccct tctttagact ctaactggtt tattgggtat ggtgcagtct tattcattat
     3961 gacattttca ggaactgcta atcatacatt gtttttaaca aatacaattc gaagcgttga
     4021 ctatcacact attgaggctg ctcgaaatat gggagcaaaa ccatttactg ttttccgaaa
     4081 agtagtgtta ccaaccttaa ttccaactct atttgcactt actattatgg tttttcttag
     4141 tggtttatct gcagtagcag cacccatgat tgttggtggt aaagaatttc aaactataaa
     4201 tccaatgatt attacatttg cagggatggg gaattctcgt gatttagctg ccttacttgc
     4261 aattatttta ggtattgcaa ctacaatttt gcttactatc atgaataaga tagaaaaagg
     4321 tggaaattat atttctatct ctaagactaa agcgcctctt aaaaaacaaa aaattgcgtc
     4381 taagccttgg aatatcattg ctcacattgt agcatatgga ttgttcacag ttttcatgct
     4441 tccactaatt tttatagtat tatactcatt tacagatcca gttgcaattc aaacaggtaa
     4501 cttaacatta tcaaacttta ctttagaaaa ttatcgctta ttctttagta atagtgcggc
     4561 attctctcca ttcttggtca gctttattta ttctattatt gctgcgacaa cagcaacaat
     4621 tctcgcagtt gtatttgctc gtgttgtcag aaaacataaa tctcgttttg atttcttatt
     4681 tgaatatggt gctctacttc cttggttact accaagtaca cttttagcag taagtttatt
     4741 atttactttt aatcagccac aatttcttgt tttgaatcag attttggtag gtagtttggt
     4801 aattctactt attgcatata tagttgtaaa aatcccattt tcttatagaa tggtacgtgc
     4861 tattttattt agtgttgatg atgagatgga agatgcagca agaagtatgg gtgcttcacc
     4921 tttttatact atgatgaagg ttatcattcc atttatttta ccggttgttc tctctgttat
     4981 tgctttaaac tttaactctt tattaactga cttcgactta tctgtattcc tttaccatcc
     5041 cctagctcaa ccattaggta ttacgattcg atctgcaggt gatgaaacag caacatctaa
     5101 tgcacaagct ctggtatttg tttatacaat tgttctgatg attatttctg gaacggtatt
     5161 atacttcaca caaagaccgg ggcgtaaagt aaggaaataa tcatgacagc cactagtctt
     5221 gggttatcaa atattgaaat agttgtcagg attgttttat cagtagtcat tggtagtata
     5281 attggtttag agagagggag caaatcccag cctgcaggca tccgaactta tagtattgtt
     5341 tgtctagctg catgtttgat tatgatgacg aatgaatacg tatcttataa atttgggaca
     5401 ggagatccta cacgattagg agctcaagtt atatcaggtg tgggttttct aggcgctgga
     5461 acgattctta ttacagataa aaagaaaatt acaggtctga caactgcagc aggcatttgg
     5521 gcttcggcag gaattggatt agctattgga gtaggttttt atgagggagc tcttttagta
     5581 gccatttctg tttggggtgt gatatccatg ttccaaccac taaaaaaata tctgcaaaat
     5641 cgttctaaaa tgattgaatt gtatatagtg gttaaatcta cagaagccta taatcgtgta
     5701 ttggtttatt gtgcagaaaa tggtatcaga atgaccgatt caagaacagc gtttggagat
     5761 gttaattctg acagaattga atactttgat gttccggaca aaaaaatagc gtcatttatt
     5821 actctggaat tatcaggtag atttgaacat cttcggctga tggaagaaat tgctaatatt
     5881 gtaggtgtta tttatgtcga agaaattagc tgaaatttag taaacaaagg gacagatgtt
     5941 tttgtccttt tgctttttag atgttttaat catctaattt ttgagtagat ttttgctcag
     6001 aggtttttat gaaagattat aaaatc
//
LOCUS       DAVLIK010000081         6004 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLIK010000081 DAVLIK010000000
VERSION     DAVLIK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.081"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            69..311
                     /locus_tag="VXE87_001985"
     CDS             69..311
                     /locus_tag="VXE87_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0843463.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            313..567
                     /locus_tag="VXE87_001986"
     CDS             313..567
                     /locus_tag="VXE87_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0843464.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            614..1309
                     /locus_tag="VXE87_001987"
     CDS             614..1309
                     /locus_tag="VXE87_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEV0843465.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(1646..2632)
                     /locus_tag="VXE87_001988"
     CDS             complement(1646..2632)
                     /locus_tag="VXE87_001988"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0843466.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2826..5294
                     /gene="gyrA"
                     /locus_tag="VXE87_001989"
     CDS             2826..5294
                     /gene="gyrA"
                     /locus_tag="VXE87_001989"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0843467.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5294..>6004
                     /gene="srtA"
                     /locus_tag="VXE87_001990"
     CDS             5294..>6004
                     /gene="srtA"
                     /locus_tag="VXE87_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0843468.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWNAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILT"
BASE COUNT         1892 a          995 c         1310 g         1807 t
ORIGIN      
        1 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
       61 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
      121 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
      181 ccctagaaga tgaatacgat gctcgtgtgg cagatttagc ctatcaagag tatttagaag
      241 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
      301 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
      361 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaagac
      421 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
      481 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
      541 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacagta tagaaagtaa
      601 ggagagtaaa aatttgaaga aaaaatggtt ttttgcagat tattatgaca caacaattat
      661 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgactgattt
      721 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
      781 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
      841 tttattgacc attctccctt taaatgctat ttttacagtg tttcgattag gacgtatctt
      901 ccgcttagca aggctgacaa aattactgaa actgactcgt ttacttagaa taattggact
      961 tacaggtaaa ctagaaagaa aaattagtag attcttacga acaaatggat tgatttatat
     1021 cttgtatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
     1081 aaaatccttc tcagatagtc tttggtgggc tcttgtgaca gtaactactg ttggttatgg
     1141 tgatattgtt ccagtttccc tttttgggaa atggctagca gttttactga tgcttgtcgg
     1201 tattggaaca atagggatgc taacaagtgc tttgacgaac ttttttgtaa aggataatcc
     1261 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagctaaa gaatattaat
     1321 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
     1381 aatatcataa aggtgagaca aaataaaact tgattcgagg agaaatcaag taagtcttga
     1441 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
     1501 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
     1561 tgatggggtg ctatttcaac ttcaacctac tataatacag aaaaaaacaa ctccctgatg
     1621 attcaaggag ttgtctatag ttaaattagt ttttagaagc ttcttggaat tctggatttt
     1681 tccatgcttc gtcaataata gcttgcaatt ctttagcaga tgcttgcatt ttttgagttt
     1741 ctgcatcgtt caatggaatg tttactggac gaacgatacc atgtgcacca acaacagctg
     1801 gttgaccgat aaagacattc tcaactccgt attgaccttc ttggaatact gaaagtggaa
     1861 gtactgcgtt ttcatcgtca aggattgctt tagtgatacg agcaagggct actgcgatac
     1921 cgtagtatgt tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga acaccttcga
     1981 acaattcaat caattcagct tcttgaacat tttgagtgtc tttaaggaat tcttcaaggt
     2041 ttacaccagc gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg tgttcaccca
     2101 tgatgtaggc gtgcactgaa cgagcatcca catccaattt ttcagcaagt gcttgacgga
     2161 aacgagctga gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg aaaccagaga
     2221 atttccaagt tgagtaagtc aaaacgtcaa ctgggttagc agcaacaagg aagatacctt
     2281 tgaaaccaga ttcaacaact tgagttacga ttgatttgtt gatagcaagg tttttaccta
     2341 caaggtcaag acgagtttca cctggttttt gaggtgcacc tgcagtgatc acaacaaggt
     2401 cagcgtctgc acagtcagag tattgagctg catagatttt tttaggtgaa gtgaaggcaa
     2461 gggcgtgact aaggtcaagc gcatcaccaa cagctttttc atgcaattgt ggaatttcga
     2521 taattccaag ctcttgtgca attccttggt taacaagtgc aaaagcgtaa gatgaaccta
     2581 cagcaccatc accgacaagg ataacttttt tgtgttgttt agttgaagtc attgttttaa
     2641 acatctcctt aattttatta ggggattttc cctagacaac ttcattctat cacttttaaa
     2701 aaactttgtc acgaatatgc cttatagttc tcgatgtaaa cgttttagtg gtttagaggc
     2761 tgaaatagat gggaatttat ggtataatgt tgttacttac taattgtgaa atgaggcatt
     2821 tattaatgca ggataaaaat ttagtgaatg tcaatctgac aaaggagatg aaggcaagtt
     2881 ttatcgacta cgccatgagt gttatcgtag cgcgagctct tcctgatgtt cgagatggct
     2941 taaaacctgt tcaccgtcgc attctctacg gaatgaatga attgggtgtg accccagaca
     3001 aaccccataa aaaatctgct cgtattacag gggatgtcat gggtaaatat cacccacacg
     3061 gggattcctc tatttatgaa gccatggtcc gtatggctca atggtggagc taccgttaca
     3121 tgcttgtaga tggtcatggg aattttggtt ccatggatgg agatagtgct gccgctcaac
     3181 gttataccga ggcacgtatg agcaagattg ctctggaaat gcttcgtgat atcaacaaaa
     3241 atacagttga tttcgttgat aactatgatg ccaatgaacg ggaacccttg gtcttgccag
     3301 cgcgttttcc aaaccttttg gttaatggag caactggtat cgcggttggg atggcaacca
     3361 atattccacc tcataatctg ggtgaaacca ttgatgcagt gaagttggtc atggataatc
     3421 ctgaagtgac taccaaggac ttgatggaag tcttgcctgg accagatttt ccaactggtg
     3481 ctcttgtcat ggggaaatca ggtatccata aggcttatga aacaggtaaa ggttcgattg
     3541 tcctacgttc tcgtacagag attgaaacga ctaagactgg tcgtgagcgc atcgttgtaa
     3601 cagaatttcc ttacatggtc aataaaacca aggtgcatga gcatattgtt cgcttggttc
     3661 aggaaaaacg cattgagggt atcacagcag tacgtgatga gtcaaaccgt gaaggtgttc
     3721 gatttgttat tgaagtcaag cgcgacgcct cagccaatgt tattctcaat aacctcttca
     3781 aaatgaccca aatgcaaacc aattttggtt tcaatatgct cgctatccaa aatggtatac
     3841 cgaaaatttt gtctcttcgt cagattttgg atgcttatat cgagcaccaa aaagaagtgg
     3901 ttgttcgtcg tacacgtttt gataaggaaa aagcggaagc gcgcgctcat atcttagaag
     3961 gtctcttgat tgcgctagac catatcgacg aagtgattcg tatcatccgt gctagtgaaa
     4021 cggatgcgga agctcaagct gagttgatga gcaagtttaa gctttctgaa cgtcaaagtc
     4081 aagctatcct tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat aagattcaat
     4141 ctgagtatga tgacctcttg gctctgattg cggatttagc agatattctt gctaagcctg
     4201 aacgtgtttc tcaaattatc aaagacgaat tggatgaagt taaacgtaaa ttttctgata
     4261 aacgccgtac agagttgatg gttggacaga tcttgagtct cgaggatgag gacttgattg
     4321 aagaatcgga tgtcttgatt accctttcta acagaggcta cattaagcgt ttggatcagg
     4381 acgagttcac tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga gtgaaagatg
     4441 atgactttgt tcgtgagtta gtgtcaacta gcacacatga tcatctgctc ttcttcacaa
     4501 acaagggacg tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt cggactgcca
     4561 aagggctacc agtagtcaat ctcttgaaat tggatgaaga cgaaagtatt cagacggtta
     4621 tcaatgttga gtctgatcgc agtgatgatg cttatctctt ctttacaacc cgtcacggta
     4681 ttgtgaagag aactagtgtt aaggagtttg ccaatattcg tcaaaatggt ctcaaagcgc
     4741 tgaatttaaa ggatgaagat gagttaatca atgtcttgtt ggcagaagga gatatggata
     4801 ttatcattgg taccaagttt ggttatgcag ttcgctttaa tcaatcagcc gttcgtggta
     4861 tgagccgtat cgccactggt gtgaaaggtg ttaaccttcg tgaaggagac acagttgttg
     4921 gtgccagctt gattactgat caagatgagg ttcttattat cacagaaaaa ggatatggta
     4981 agcgtacagt cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga atgcagacag
     5041 ctaaaattac cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa ggggatgagg
     5101 atttgatgat tatcactgat acaggtgtca tgattcgaac caatcttgcc aatatttcac
     5161 aaacaggacg tgcaactatg ggagttaaag taatgcgcct ggatcaagat gctcagatag
     5221 tgactttcac aacggttgcg gtggcagaaa aagaagaagt tgggacagaa aacgaaacag
     5281 aaggtgaagc ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa aaaatctgct
     5341 gacaaatatc ctagcaggat ttctgatatt actgtcactg gctttgattt ttaatactca
     5401 aattcgaaat attttcatag tctggaatac caataagtat caagttagcc aggtatcaaa
     5461 agaaaaatta gaagaaaatc aggatacaga aggcaatttt gactttgatt ctgtcaaagc
     5521 tatctcttcg gaagctgttc taacttctca atggaatgct caaaaattac cagttattgg
     5581 gggaattgca attcctgaat tggaaatgaa tttgccgatt tttaaaggac ttgataatgt
     5641 taatctcttc tacggagctg gtacaatgaa acgcgagcaa gtaatgggag aaggaaatta
     5701 tagtctagct agtcaccata tctttggtgt tgataatgct aataaaatgt tattttctcc
     5761 tttagataat gctaaaaatg gcatgaagat ttatctaacc gataaaaata aagtttatac
     5821 ttatgaaata cgtgaagtca aacgtgtgac accggatcgt gttgatgaag ttgatgatag
     5881 agatggggtc aatgaaatca cattagtaac ctgtgaagac cttgctgcta cagaacgtat
     5941 tattgtcaaa ggtgatttga aagaaacaaa agattattca caaacatctg atgaaatcct
     6001 aaca
//
LOCUS       DAVLIK010000082         5911 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLIK010000082 DAVLIK010000000
VERSION     DAVLIK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5911
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.082"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            114..509
                     /locus_tag="VXE87_001991"
     CDS             114..509
                     /locus_tag="VXE87_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0843469.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            520..891
                     /locus_tag="VXE87_001992"
     CDS             520..891
                     /locus_tag="VXE87_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0843470.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            901..3144
                     /locus_tag="VXE87_001993"
     CDS             901..3144
                     /locus_tag="VXE87_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0843471.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRVNGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            3351..5126
                     /gene="spxB"
                     /locus_tag="VXE87_001994"
     CDS             3351..5126
                     /gene="spxB"
                     /locus_tag="VXE87_001994"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0843472.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            5237..5584
                     /locus_tag="VXE87_001995"
     CDS             5237..5584
                     /locus_tag="VXE87_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0843473.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(5701..>5911)
                     /locus_tag="VXE87_001996"
     CDS             complement(5701..>5911)
                     /locus_tag="VXE87_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843474.1"
                     /translation="FAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRTLEDVINQLQDV
                     IQGLEKEVIKSIVNRRWTRMLFESR"
BASE COUNT         1749 a         1101 c         1347 g         1714 t
ORIGIN      
        1 atgattaaaa ttctattttt cgaagaaaat attatttcta taattgacaa atgtagattt
       61 taagagtata ctgatgagtg taattgacaa atgtagattt tggaggtatg gtaatgcaga
      121 tttcagatgc agaatggcag gtcatgaaga ttatttggat gcagggggag cagaccagta
      181 cggatttgat tagggttttg gcagagcgat ttgattggtc caagtccacg gttcagacac
      241 ttttggctcg gctggttgag aaagagtgtt tgactcggaa aaaagaaggc aagtcctttg
      301 tttattcagc ccttttaact ctagaccaaa gtcgggattt acttgtccaa gatatcaaag
      361 acaaggtttg ttcccgtagg attaggaatt tgttggctga cttgattgta gaatgtgaat
      421 ttactcagac tgacttggaa gacttggaag ctgtgatttc agagaagaaa tcaagtgctg
      481 taacagaagt aagatgtaat tgtatgtaaa ggagacgtca tgttaaatag tattgtaacc
      541 attatttgta ttgcccttat cgcgtttatc ttgttttggt ttttcaaaaa gcctgaaaaa
      601 tctggacaaa aagcccagca aaaaaacgga taccaagaga ttcgagtgga agtcatggga
      661 ggctatactc ctgagttgat tgtcctcaag aaatcagtgc cagcacgcat tgtctttgac
      721 cgcaaggatc cttcaccatg tctggatcaa attgtttttc cagattttgg tgtacatacg
      781 aacctgccaa tgggggaaga gtatgtagtg gaaatcacgc ctgagcaggc tggagagttt
      841 ggctttgctt gtggtatgaa catgatgcac ggcaagatga ttgtagagta ggtggagact
      901 atgacagaaa ttgtgaaagc aagcttagaa aatggcattc aaaaaatccg tatccgagct
      961 gaaaaaggct atcatccagc ccatatccag cttcaaaagg gaattccagc tgagattacc
     1021 tttcatcgtg ctactccttc aaactgttat aaggaaattc tgtttgaaga agaaggtatc
     1081 ttggaaccaa tcggcgtaga tgaggagaaa gtcattcgtt ttacacctca agaattaggg
     1141 cgacatgaat tttcttgtgg catgaagatg caaaagggaa gctatatagt cgttgagaag
     1201 actcgaaaat ctctatctct cctgcaacgt ttttggatta ctagtatctt tactgtgcct
     1261 cttgtgattc tcatgattgg gatgttggca ggtagcatta gtcatcaagt catgcattgg
     1321 ggaacctttt tagcaacaac gcctattatg ttagttgcag gtaagccata tatccagagt
     1381 gcttgggcca gttttaaaaa gcacaatgcc aacatggata ccttggttgc gctgggaact
     1441 ctagtggctt atttctatag cctagttgct ctctttgctg gtctccctgt ttacttcgaa
     1501 agtgctggat ttatcctctt tttcgttctt ttgggagcag tttttgagga aaaaatgaga
     1561 aaaaatacgt cccaagctgt ggagaaatta ctggacttgc aagctaaaac cgcagaagtc
     1621 ttgagtgatg atagttatgt ccaagttcct ttggaacaag tcaaggtagg cgacctgatt
     1681 cgagtgcgtc ccggtgaaaa gattgctgtt gatggtgtcg tagtagaagg tgtctctagt
     1741 attgacgaat ccatggtgac aggtgagagt ctgcctgtgg acaagacagt tggagatact
     1801 gtcattggct caaccatcaa tcatagtgga acgcttgtct ttagagcaga aaaagttggc
     1861 tcagagactg ttttggctca gattgtggat tttgtgaaga aagctcagac aagtcgtgcg
     1921 ccgattcagg acttgacgga taagatttca gggatttttg tcccagtagt tgtcatttta
     1981 ggaatcatga ccttttgggt ttggttcgtc ttgctcaggg atagtgtggt cgtgcttgga
     2041 gctagctttg tgtcctctct tctctacgga gtggcggttt tgattatcgc ctgtccttgt
     2101 gccttgggac ttgcaacacc gacagccctt atggtgggga caggacgtag tgccaagatg
     2161 ggggttctcc tcaaaaatgg aactgtctta caggaaatcc agaaagttca aactcttgtc
     2221 tttgataaga ccgggacttt gacggaaggg aaacctgtgg taacagatat catcggcgac
     2281 gaagtagaag tgtttggatt ggcagcctcc ttggaagatg cttctcaaca cccactggct
     2341 gaggctatcg ttaagcgagc gagtgaagct ggacttgagt ttcaaactgt tgaaaatttt
     2401 caggccttgc acgggaaagg tgtttcaggg cgagtcaatg gaaaacaagt tttacttgga
     2461 aatgctaaaa tgctggatgg catggatatt tctaatactt atcaagataa actagaagaa
     2521 ctagaaaaag aagctaagac agttgtgttt ttagctgttg acaatgaaat caaaggcttg
     2581 cttgctttgc aagatattcc taaggaaaat gctaagctag ccatcagtca gctaaaaaaa
     2641 cgtggtctcc gaacagtcat gctgacagga gacaatgctg gtgtggcgcg tgctattgca
     2701 gatcaaatcg gaattgaaga ggtcattgca ggcgtcttgc cagaagaaaa agcccatgaa
     2761 atccataaac tgcaagcggc tggcaaagta gcctttgttg gggacggtat caatgacgct
     2821 cctgccctta gtgtagcaga tgtgggaatt gctatgggtg ctggaacaga tatcgccatc
     2881 gagtcagcag atttggtgtt gacaaccaat aatcttttag gagtggttcg tgcctttgat
     2941 atgagtaaga aaacctttca tcgaattcta ctcaatcttt tctgggcttt tatctacaat
     3001 gttgtcggaa ttccgattgc agcaggagtc ttttcaggtg ttggactggc tctcaaccca
     3061 gaattggcag gtctagccat ggcctttagt tctgtatctg ttctgaccag ttcccttctg
     3121 ttaaatttta gtaaaataga ctaaaagtaa tgactagatt tctttgttat aaaacagaaa
     3181 tgacaacact ttcaaaactg tattagaata gagaatagag agttttgagc agatttttag
     3241 aaaagtcagc ataaatatga tacagtggaa tagtaaaaat ttggagaacg tttccaattc
     3301 tatgtaatcg tattctccaa gtttaaaaaa attgaaggag agttatcatt atgactcaag
     3361 ggaaaattac tgcatctgca gcaatgctta acgtattgaa aacatggggc gtagatacaa
     3421 tctacggtat cccatcagga acactcagct cattgatgga tgctttggct gaagacaaag
     3481 atatccgttt cttacaagtt cgccacgaag agacaggtgc tcttgcagcg gttatgcaag
     3541 ctaaattcgg cggctcaatc ggggttgcag ttggttcagg tggtccaggt gcgactcact
     3601 tgattaacgg tgtttacgat gcagctatgg ataacactcc attcctagcg atccttggat
     3661 cacgtccagt taacgaattg aacatggatg ctttccaaga gcttaatcaa aacccaatgt
     3721 acaacggtat cgctgtttac aacaaacgtg tagcttacgc tgagcaattg ccaaaagtaa
     3781 ttgacgaagc ctgccgtgct gcagtttcta aaaaaggtcc agctgttgtt gaaattccag
     3841 taaacttcgg tttccaagaa atcgatgaaa actcatacta cggttcaggt tcatacgaac
     3901 gctcattcat cgctcctgct ttgaacgaag ttgaaatcga caaagctgtt gaaatcttga
     3961 acaatgctga acgcccagtt atctatgctg gatttggtgg tgttaaagct ggtgaagtga
     4021 ttactgaatt gtcacgtaaa atcaaagcac caatcatcac aactggtaaa aactttgaag
     4081 ctttcgaatg gaactatgaa ggtttgacag gttctgctta ccgtgttggt tggaaaccag
     4141 ccaacgaagt ggtctttgaa gcagacacag ttcttttcct tggttcaaac ttcccattcg
     4201 ctgaagttta cgaagcattc aagaacactg aaaaatttat ccaagtcgat atcgaccctt
     4261 acaaacttgg taaacgtcat gctcttgacg cttcaatcct tggtgatgct ggtcaagcag
     4321 ctaaagctat ccttgacaaa gtaaacccag ttgaatcaac tccatggtgg cgtgcaaacg
     4381 ttaagaacaa ccaaaactgg cgtgattaca tgaacaaact cgaaggtaaa actgagggtg
     4441 aattgcaatt gtatcaagtt tacaatgcaa tcaacaaaca tgctgatcaa gacgctatct
     4501 actcaatcga cgtaggtaac actactcaaa catctactcg tcaccttcac atgacaccta
     4561 agaacatgtg gcgtacatct ccactctttg cgacaatggg tattgccctt cctggtggta
     4621 tcgctgctaa gaaagacaat ccagatcgcc aagtatggaa catcatgggt gacggagcat
     4681 tcaacatgtg ctacccagac gttatcacaa acgttcaata cgaccttcca gttatcaacc
     4741 ttgtcttctc aaatgctgag tacggcttca tcaagaacaa atacgaagat acaaacaaac
     4801 acttgtttgg tgtagacttc acaaacgctg actacgctaa aattgcggaa gctcaaggag
     4861 ctgttggatt cacagttgac cgtatcgaag acatcgatgc agttgttgca gaagctgtta
     4921 aattgaacaa agaaggtaaa actgttgtca tcgatgctcg catcactcaa caccgtccac
     4981 ttccagtaga agtacttgaa ttggatccaa aacttcactc agaagaagct atcaaagcct
     5041 tcaaggaaaa atacgaggca gaagaactcg taccattccg tctcttcttg gaagaagaag
     5101 gattgcaatc acgcgcaatt aaataattcc tctcgccgaa aatcaaatat gaaacttgta
     5161 gactttattc tttgattttc atagagcaga actttaaaag atcggagcaa tccggtcttt
     5221 ttatggagga gagtaaatga atttaaatca attagatatt atcgtttcaa atgttcccca
     5281 agtctgtgct gacttggagc atatcttgga taaaaaggca gattatgctg atgatggttt
     5341 tgctcagttt acgattggta gtcactgcct tatgttgtca caaaatcatt tggttccttt
     5401 ggaaaacttt cagtcaggaa tcattattca tatcgaggtt gaggatgtag accagaacta
     5461 caaacggttg aacgagcttg gtataaaggt tttacacgga ccaactgtaa ccgattgggg
     5521 aacagagtcc ttattagttc aaggacctgc tggtctagtg cttgattttt atcgtatgaa
     5581 ataggtcgcg tagtcatttg acgttaacct tagctatttt taaaatagaa attgagaata
     5641 tgaactattg aaagatcgga gcaatccggt ctttttatat aaagaaattg catataatac
     5701 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     5761 cttctccagt ccttgtatga catcttgaag ttgattaatg acatcttcca aagttcgaaa
     5821 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
     5881 ctctggtgtg tatggaggaa taaatgcaaa g
//
LOCUS       DAVLIK010000083         5537 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLIK010000083 DAVLIK010000000
VERSION     DAVLIK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.083"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            159..1019
                     /locus_tag="VXE87_001997"
     CDS             159..1019
                     /locus_tag="VXE87_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEV0843475.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLDKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NVMYMPIIKTIEELDFVLSFEGINTVAVELVFQDLENPIISKKIIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     IKENYHVQKL"
     gene            1003..2064
                     /locus_tag="VXE87_001998"
     CDS             1003..2064
                     /locus_tag="VXE87_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0843476.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNDLKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            2081..3085
                     /locus_tag="VXE87_001999"
     CDS             2081..3085
                     /locus_tag="VXE87_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843477.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSATQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIKEKVTMYINPRDIMQF
                     "
     gene            3097..4791
                     /locus_tag="VXE87_002000"
     CDS             3097..4791
                     /locus_tag="VXE87_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0843478.1"
                     /translation="MRKSLNWKDCLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            4793..5494
                     /locus_tag="VXE87_002001"
     CDS             4793..5494
                     /locus_tag="VXE87_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0843479.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNRLLIYLNTSGIKILEIQNGIGNLDEERQLNKIKSTKVSCYLSLKLNENFEHLKLME
                     EMHNIAGVIYVEEIR"
BASE COUNT         1911 a          761 c          999 g         1866 t
ORIGIN      
        1 acattttata tttaacaatt atttaaaata ataaaattat aacattataa cattatataa
       61 attattttaa aaaataatga aacgttccaa cttatctatt gacacgttcc aagaaatcgg
      121 atacaatgta attaacaata aagataggag aaaataattt gaatccatta aaagaatgct
      181 atgaaaaaaa cggtatacta attgcagcac accgtggtac aaacggagga aatatattac
      241 aaaacacatc aaaagcctat ttgaattcca tacgccataa cgcagatatg tttgaggttg
      301 atgtaattcg ttcaaaagat ggagaatttt ttgcatttca cgatgggcaa gaacctttag
      361 tatttggtga aaaaattgat attagaactt tgagttctga agagatccaa agaaaggaat
      421 gttttaattc actgaatgaa cccatattac aaaagattga aaaaatttct gatgtattaa
      481 aaaattttga gggacagtct ttaataaata tagatagaag ttggttttac tgggatacct
      541 tcctagataa gttaaaaaca tatccatctt tgaatcaagt tcttttaaaa tcacctgtaa
      601 aaaaagaatt attggaaatg cttagagact ctggtttgaa tgttatgtat atgccaatta
      661 tcaaaacaat tgaagagtta gattttgttc tctcatttga aggaataaat acagtagctg
      721 tcgaacttgt attccaagat ttagaaaatc caatcataag taagaaaata attgatgatt
      781 tacatgaaaa aggattactt atttgggtta atgctttaac cttaagtgat tcaattattc
      841 tttcggctaa gattgatgat gatacagcta ttgctcatga tggcgaatct tgggggaaat
      901 tggtttcaat aggatttgat attattcaaa cagattggcc attattactt tatcaatatc
      961 tagttgaaaa aaataaaaaa ataaaaataa aggagaacta tcatgttcaa aaactttaaa
     1021 aagattgcat tcacttcttc actaatttta cttgctgctt gctcaaacaa tgcttcaaat
     1081 acaaatcagt ctactgatga aggaagtgtt gataaatctc aagaaattgt aatctataca
     1141 aattcggctt ctaatggacg tgcagattgg ttacaaacta aagcatcaga gcaaggatac
     1201 aatcttcgtt tggtagatat ttcaggtgga gaactagctg accgtttgat tgcagaaaag
     1261 aataatgctg tggctgatat ggtaattgga ttaaataaat tagaatttaa ccgtattaaa
     1321 gctgaaaaac ttcttgtaaa atactcacca aaatgggctg atgaagtaga tagctctttg
     1381 ggagattctg aagggtatta ttcaccaatt gtaaatcaac cattagtttt aattggtaat
     1441 aaagatgcta aaatgccatc cgactggaca gattttactg attcatctta taaaggtaaa
     1501 tatggtattt caaaattaag tacaggtaca tctaagaaca tctttgcaag tattgtttcg
     1561 agatataaag atgaaaaagg tgagttagga atatctgatg aaggttggaa agttgcaaaa
     1621 gcttacctta aaaatgcaca cgtttatgca gaaggtgaag actatatctc ttcaattatg
     1681 gataataata atgatctaaa atatagtatg atgtggggat ctggtgttct acaaaatcaa
     1741 aaagaacgtg aatataaatt ccaagtaatg tcaccaaaag ttggtgttcc ttatgtaact
     1801 gaacaagttg ggattttaaa tacaagtaag aagcaagcat tattaaaaga atttgtagat
     1861 tggtttggct cttcagaact tcaaaaagaa tggtctgata aatttggttc aattccagct
     1921 aataaaaaag ctctagagca agcaaaagat gaactcaaac agtttgctaa tagtgttaaa
     1981 ccacaagaac ttgactggga gtttatcggg aaaaacatcg attcttggat tgaaaaagca
     2041 cagcttgaat ttgttgaaca ataatagtta ggattaagtg atgattacat ttaaggatat
     2101 tcaaattaag tataatgatt ttattgccat cgataatctc aatttaacaa tcaatgaggg
     2161 agagtttttc acatttttag gaccaagtgg ttgtgggaaa tcaacaactc ttcgtgcact
     2221 agttggattt ttggagcctt cacaggggca aatactagtt gataatcaag atattacgaa
     2281 tttagatccg gaaaaacgcg aaattggtat tgtgtttcaa agttatgcat tattcccaac
     2341 aatgactgtt tttgataata ttgcttttgg tctaaaagtt aaaaaagttt ctcctgaaat
     2401 tattaaagct aaagttcatg aaattgcgaa aaaaattaat atctcagacg agcaactaaa
     2461 ccgaaatatt tctgaattat cagggggaca acaacagcgt gtagctttag cacgtgcatt
     2521 agtattagaa ccaaaaattc tttgtttgga tgaaccgtta tcaaacctag atgccaaact
     2581 acgagtttcg ttgagaaaag aattgaaacg attgcaaaaa gaactaggaa tcactactct
     2641 ttatgtcaca catgatcaag aagaagcatt aacattatca gataggattg ctgtgtttaa
     2701 taatggattt attgagcaag ttggcacgcc gtatgatatt tataatcaat ccgcaactca
     2761 atttgtctgt gattttattg gctcaatcaa taaaattagc caagaagttc ttaaaaaatt
     2821 acaaggcgag aataaatact ttaaagaaac tgaaggatac atacgcttag agcgtgttaa
     2881 gttagagaaa acttcacctc aagatttatc tataacaggg gtaattagtg atattgagtt
     2941 taatggtgta cttattaagt ataaagtaga cttgtcgaat agtgaaagta ttcatattat
     3001 cgaaaagaat gatggactat cacgtcatat aatcaaagaa aaagtcacta tgtacattaa
     3061 tccgcgtgat ataatgcaat tttaaggaga ttgtgcatga gaaagagtct aaactggaaa
     3121 gattgtctca taagattagg agttttatgg ctaatctttg ccctgattat ttatccaaat
     3181 attgaacttt tgtctggagt gttttataaa aatggttcat ttactctaga ggcattcaat
     3241 aagattatac actctcagag agcgatgagt agtatattta atagctttat tttggcgatt
     3301 tcaatggtct ttactgtaaa tattgttggg acattgattg ttctactcac agagtactgg
     3361 gatattaggg gttcaaaaat acttaaatta ggttatatga gctctctagt atatggagga
     3421 attgtattag cgacaggata taaatttgtt tatggcgcta atggtcttgt aactaaaacg
     3481 ctctcaagta taattccagg tcttgcccct aactggtttc aaggatttgg tgcagtattg
     3541 tttattatga catttgcttg tacctcaaat cacataatgt ttttaacaaa tgcagttcgt
     3601 agtgttgatt atcatacaat tgaggcagct aaaaatatgg gtgcaagtcc tttaaaagtt
     3661 ttctttagtg tggtttttcc aacttttaaa cctacgttat ttgccttaac catcttaact
     3721 tttttgacag gtctttcagc agtttctgct cctttgatag taggggggaa agattttcaa
     3781 actattaacc cattgattat cagtttcgct aaaactacaa gttcgagaga tttagcagct
     3841 ttactagcta tcatgttagg tttagcaact attctattat tgacactttt gaatcatgtc
     3901 gaaaaaggag gtaattatgt atctgtttcg aaaaccaagg ctagtattaa gaagcagata
     3961 atttcttctc cattatggaa tactcttgct cacattgttg cgtatgtatt gtttgcaatc
     4021 tatatgttac caatagtttt gataattcta tactcgttta cagactcgtt gacgatcaag
     4081 acgggaactt tagatctatc taaatttacg ttagcgaact atgctaattt atttacagat
     4141 gctcaatcat ttcgtcctta cctagtcagc gttgtttatg caattttagc tgcggtaatt
     4201 gctacaatta tagcaatagt aatttcacgt attgtacata aaaacaagag taagttcgat
     4261 aaattctttg agtatggtgc actgatacca tggatattgc caggtacatt gattgcacta
     4321 ggattaatgt tcacttataa tatacctcat ttaatactat ttaatttagt tttagtagga
     4381 acagtaatta ttttacttat tgcatatact attcaaaaat taccattttc ttatagaatg
     4441 attcgggctg tatttttcag tatagataat gatatggaag aagctgcacg tagtatgggt
     4501 gcatctagtt tctacactat ggtgcgagtt attataccgt atattttacc agtcgtatta
     4561 tcagtagttg tgttaaactt taattcttta ttatctgact atgacttatc tgtattcttg
     4621 taccatccac ttttccaacc attgggaatc gttattaaac agtctactga tgaaacagca
     4681 actttaaatg cacaggcaat gatgtttgtt tattctgtaa ttttaatgat tatgtctagt
     4741 gcagctcttt atttatcaag cctattccaa ggtaaacgag gtaagagata atatgaatct
     4801 ttcatacgaa ctgagtattt gggaaatact tcttaggtgc tttttagcga ttcttttcgg
     4861 tggcattgtt ggctatgagc gaggagtcaa aaaccaagca gcagggatta gaacctactt
     4921 actagtttgt ttgggaactt gtgttgtaat gatgacaaat cagttcatca ctagtcgtta
     4981 tggtagcggt gatcctagtc gaatgggagc ccaagtaatt agtggcttgg gtttcctagg
     5041 ggcaggaaca atcatggtaa ctaatcaaaa agttaaaggt ttaacaacag cagctggatt
     5101 atggtcttca gcaactattg gtttagctat aggcattggt ttttatgaag gtgctatttt
     5161 agccggagtt gtactcatag cagttttaac tctatttact cctcttaaag attatttaaa
     5221 ctcgaaaact aaaattgctg attactactt ggtttttagt tctttagaag gttataatcg
     5281 tttacttata tatttaaata catcgggtat taagatttta gaaattcaaa atggtatagg
     5341 aaatcttgat gaagaacgtc aattaaataa aattaagtca acaaaagtgt cctgctattt
     5401 atcattaaaa ttaaacgaaa actttgaaca tttaaaatta atggaagaaa tgcataatat
     5461 tgctggtgtt atttatgttg aagagattag gtaagggtga ctttgtctaa ttttttctat
     5521 atttctaatc ggagaaa
//
LOCUS       DAVLIK010000084         5514 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLIK010000084 DAVLIK010000000
VERSION     DAVLIK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5514
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.084"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            32..289
                     /locus_tag="VXE87_002002"
     CDS             32..289
                     /locus_tag="VXE87_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0843480.1"
                     /translation="MDIRKKIIELCIKINPHLEDHYFYDYEKMIDDLDFDSLTITQLV
                     IDIEEQFDIMLPPQKISMSEMETFGKIVDLVHKCITSKESR"
     gene            286..1476
                     /locus_tag="VXE87_002003"
     CDS             286..1476
                     /locus_tag="VXE87_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843481.1"
                     /translation="MMPQITQFLNNIKNNNEYYSNIINDATVLDDIPILNKNDIRLNP
                     DSIISECYSKKDLIHETTNGTTDYHPLDLYKTPQERVDLNFSLWKERRKFISASNIKS
                     VKIAVFYYSHDSLMNHDGSLKKVSGLIQVPMNRADDNQYIADLKYLIEEEIKWLIGPV
                     SIFLKYAKICKKYCIKFNVEYCECTSEYVPEVYRKEIEDVFKCKFLMQYSCHELWGIA
                     FTNSLEMYNVLKPLDNSIVEGLLRKEFTSKKLYSPVVTSLTLKAMPFIKYLLTDLVYF
                     DNGYIIPFGFRYTDMVKLKTDTIHCSIFDNLFGTLPFKFEPLEQYQIIYDAQNSEIVV
                     NVLNLEVTQGDIVCSVLKEYIKEHYKSSIKVSLRNCSKFFRDNLTGKMRGIINKENIN
                     NEIW"
     gene            1492..2997
                     /locus_tag="VXE87_002004"
     CDS             1492..2997
                     /locus_tag="VXE87_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEV0843482.1"
                     /translation="MDNENEISKFFLSSENVKDMKTIANDILNMGLDFKLSEKVSQKK
                     MKEHDDLNFLSLEESIDNLPQLLEEFREKVIPYCTNFSSPNFMGFPDSGNSLGGLSGS
                     LLSDLLQQNLINASFCAPVATIMEINVIQWLRKVLGYSTSDVHNIMEVGGIVTYGGTG
                     SNSTAMLLARENKDGNTLELGVRNPRNYKVIVPKGIGHYSIASSLKWLGLGNNIIEVP
                     TENYRYNLKKLREALINHSNEIMAVVAYAGDSRTMTIDNLSEVADLVKTLTPNVWLHC
                     DACHGFSLAFSKKYKDRIKGIEKFDSISTDPHKVLGIPYCISVLLVKTPQSLNLIHSQ
                     SDLIMNENLALGQTTPFLGSKSWISLKLWLVAKHLGSEKIGAMVDKRIELTNYLQDLI
                     LKSSKLILLNRTDINSVMFMYIGDKHQEVSLSSVQNINNINKSIYDRLKDEGIYYLHQ
                     FPIIDNTETIYRGFELCPLRFMSGNPNLTIEELQKMVIEVENLGDRFVGES"
     gene            3001..4473
                     /locus_tag="VXE87_002005"
     CDS             3001..4473
                     /locus_tag="VXE87_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl--CoA ligase"
                     /protein_id="HEV0843483.1"
                     /translation="MSKELYNKFILTKEAGNIIYDGIEFGRDEIDRRILEISKILTAD
                     IVNLSQEAVAISCNKKINFFFLFLVVNCCDGVVMPVYARTPENKLQHICERYDINYMV
                     SDHEINLVGYSLIYHGSVFSEEYFIYECNKSFPKHEELKGIELLMLSSGTTGVSKAIS
                     LSLDNILSNTRSIQKYIIPTREDRCLIIKEITHSSSLISELINSLLSKNSVLLSDLIP
                     TVSSLGYLISTYGVTILYAIPDFLLFMNSIKFINNYRQLLGKLRLVQVVGAFCPPNYI
                     TDFHKNWPKIDLFNGYGLTEASPRVAVLGGEELYANPRCVGYPISGVGVHIDTSSNNT
                     QEGEICVTGPNIMVEYYLNEELTSKIKIGGMLRTGDIGYFDDKNRLYILGRKDNRYIK
                     SGKNIFPEEIESVVRKLPFISEVIVYPKIESGRLISILEYTICNDEEKDLNQEASEII
                     KLCKDNLEDYKIPDQYRKVKNIPHTSTGKVKRDRNNYYNE"
     gene            4466..>5514
                     /locus_tag="VXE87_002006"
     CDS             4466..>5514
                     /locus_tag="VXE87_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEV0843484.1"
                     /translation="MNELCKKYVYQLQNELNQYCDNLEGIHVIAYGSNGSNDLSISSD
                     FDVCLIVNDDSFVAMNQRLICDFTKLFHFQENLPIDKDIPLSNKLIYLSSEVELFLDN
                     PPFISDSKKVKIEDIKKTKNFLTSRTMKQRLLLNILTTDSTVLFGDEDYVNNLKYRAW
                     EDIEKIIERAYNIKLTTKNENEFLNLLYQNPVSKASGEYYLGYKKEKRNVVKHLERNV
                     HRLAILNEKKVEDIIDLSENVNRLLLKDYSFLFPSETIKKMISTYPEKKSCSIKEVLS
                     SKLTIASNNFLITNGSLEGMNIIIANLVQNNIGYLTPTFWGYGDSAKRYNKSVISAPL
                     SDIYNYNVTEIDKIS"
BASE COUNT         2072 a          661 c          974 g         1807 t
ORIGIN      
        1 ccaaattaca aactttgaga aaggtaaaaa tatggatatt agaaaaaaaa ttattgaatt
       61 atgcattaag attaatccgc atttagaaga tcattatttt tatgattatg aaaaaatgat
      121 tgatgattta gattttgatt ctctgacaat cacgcaatta gttatagata ttgaagaaca
      181 atttgacata atgcttcccc cacaaaaaat ttctatgtca gaaatggaaa cgtttggaaa
      241 aattgttgac ttggtacata aatgtatcac gagcaaggag agtagatgat gcctcaaatc
      301 acacaatttt taaataatat aaaaaacaac aatgaatatt attcaaacat cattaatgat
      361 gccacagttt tagatgatat tccaattttg aataagaatg atattagatt aaacccagat
      421 tctattattt cagaatgtta cagcaaaaaa gatcttatac atgaaacaac taatggcacg
      481 acagattatc atccattgga tttatacaag actcctcaag aaagagttga cttgaacttt
      541 tcactttgga aagaaagaag aaaatttatt agtgcttcta atattaagtc tgttaagata
      601 gcagtttttt attacagtca tgattcatta atgaatcatg atggcagtct gaaaaaagta
      661 tcgggattga ttcaagttcc aatgaatagg gctgacgata atcaatatat tgcggattta
      721 aaatatctta ttgaggaaga aataaaatgg ctgattggtc cggtttcgat attcttgaaa
      781 tatgcaaaga tttgtaaaaa atattgtatt aaatttaatg ttgaatattg tgaatgtact
      841 agtgagtatg tccctgaagt atatagaaag gaaatagaag atgtatttaa atgtaaattt
      901 ttaatgcaat atagctgtca tgagttatgg ggaattgcat ttacaaattc attagaaatg
      961 tataatgtac ttaaaccatt agataattct atagttgaag gtctgctgag aaaagaattt
     1021 acttctaaaa aattatatag tccagttgtt acttcactaa ctctaaaggc aatgccattt
     1081 ataaaatatt tacttactga tttggtttac tttgataatg ggtatattat cccgtttggc
     1141 tttagataca cagacatggt aaaactaaaa acagatacca tccattgttc aatatttgat
     1201 aatttatttg gaacattacc atttaaattt gaacctttag aacagtatca gattatctac
     1261 gatgctcaaa attcagagat tgtggttaat gttctaaatt tagaagtgac acaaggtgat
     1321 attgtttgct cggttttaaa agaatatatc aaagaacact acaaaagttc aataaaagtt
     1381 tctcttcgaa attgttcaaa attttttaga gataatctga caggaaaaat gcgtgggata
     1441 ataaataaag agaatataaa taatgaaatt tggtaggagg caaactcata catggataat
     1501 gaaaacgaaa tttcaaagtt ttttctgagt tcagaaaatg taaaagatat gaaaactatc
     1561 gcaaatgaca ttttaaatat ggggttggat tttaaattaa gcgaaaaagt ttctcagaaa
     1621 aaaatgaaag aacacgatga tttaaatttt ctcagcttag aagagagtat agacaatctt
     1681 ccgcaacttt tggaagaatt cagggaaaaa gtaattcctt actgtacaaa tttttcttcc
     1741 cctaatttta tgggttttcc tgactcagga aattcattag gcggtctttc aggtagtttg
     1801 cttagtgatt tattacagca aaatttgatt aatgcatctt tttgcgctcc cgttgctact
     1861 attatggaaa taaatgtaat ccagtggtta cgaaaagttt taggatattc cacttctgat
     1921 gttcataata ttatggaagt aggcggcatc gttacctatg gtggtacagg aagtaattct
     1981 acagctatgc ttttagcaag agaaaataaa gatggaaata ctcttgaatt aggcgtaaga
     2041 aaccccagaa actataaggt aattgtgcca aaaggaattg gtcattatag tatcgcatca
     2101 agtttaaagt ggctgggatt ggggaataat attattgaag ttcctacaga aaattatcgc
     2161 tataacttga agaaacttag ggaagcacta atcaaccatt ctaatgaaat aatggcagtg
     2221 gttgcatatg ctggagatag tagaacaatg actattgata atctatctga agtagcagat
     2281 ttggtaaaga cacttacccc aaatgtttgg ttacactgtg atgcttgtca cggattttca
     2341 ttagcttttt ctaaaaagta taaagatagg ataaaaggaa ttgaaaaatt tgatagtatt
     2401 tcgacagatc cgcataaagt tttaggaatt ccttattgca taagtgtttt gttagtgaaa
     2461 acacctcaat cgcttaatct aattcactct caatcagatt tgattatgaa tgaaaacttg
     2521 gcccttgggc aaacgactcc atttttggga agtaaaagtt ggatatctct aaaattgtgg
     2581 ttagtagcta aacatttagg atcagagaaa ataggagcga tggtagacaa gagaatagag
     2641 ttaacgaatt atttgcaaga tctaatactt aagagttcta agttaatatt attaaatagg
     2701 acagatatta attcagttat gttcatgtat ataggtgata aacatcaaga agtaagctta
     2761 tcatcagtac agaatataaa taacattaat aagagtattt atgacagact aaaagatgaa
     2821 ggaatatact acctacatca atttccaata atagataata cagaaaccat atacagaggg
     2881 tttgaattat gtccattacg atttatgtct ggaaatccta atttaacaat tgaagaacta
     2941 caaaaaatgg ttatagaagt agaaaatcta ggggatagat ttgtaggaga gagttaaaaa
     3001 atgagtaaag agctctataa taaatttatt ttgacaaagg aagctggaaa tataatatat
     3061 gacggcattg aatttggcag ggatgaaatt gataggagaa ttctcgaaat ttctaaaata
     3121 cttactgcag atattgtcaa cttatcacaa gaagcagttg ctataagttg taataaaaaa
     3181 ataaactttt tctttctttt tctggtagtt aattgttgtg atggtgttgt tatgccagtg
     3241 tatgctagaa cgccagaaaa taaattacaa catatctgtg aaaggtatga cataaactat
     3301 atggtttctg accatgaaat taatttggta gggtatagtt taatatatca tgggagtgtt
     3361 ttttcagaag agtattttat atacgagtgt aataaatcat ttccgaaaca tgaggagttg
     3421 aaggggattg aattgttaat gctctcttca ggtactacag gagtttcaaa agcgattagt
     3481 ttatcgcttg ataatatttt atctaatact agaagcattc aaaaatatat tattcctact
     3541 agagaagata ggtgtctcat aataaaagaa atcacacact cgtcgtcatt gatatcagaa
     3601 ttaataaata gtttgttatc aaaaaattca gtgttgttaa gcgatttaat tccgaccgtt
     3661 agttcattag ggtatttaat aagtacatac ggtgtgacta ttttatacgc tatacctgat
     3721 tttctattgt ttatgaactc tattaaattt ataaataatt atagacaatt gttagggaaa
     3781 ttaagattag tacaggttgt aggtgcattt tgtcctccaa attatataac agattttcat
     3841 aaaaactggc caaaaattga tttatttaat ggttatggtt taacagaggc ctctcctaga
     3901 gttgctgtat taggaggaga agaattatat gcaaatccta ggtgtgtagg ttatccaatt
     3961 tcaggagttg gtgtgcatat tgatacaagt agcaacaaca cccaagaggg agaaatttgt
     4021 gttactggtc ctaatattat ggttgaatat tacttgaacg aagagcttac ttctaaaata
     4081 aaaattggag gtatgttaag gactggagac attggttact ttgatgataa aaacaggtta
     4141 tatattttag gcagaaaaga caataggtat ataaaatcag gaaaaaatat atttccggaa
     4201 gaaatagaat ctgtagtaag aaaattacct tttatatccg aagtaatagt ttatcctaaa
     4261 atagaatctg ggagattaat atctattctt gaatatacta tttgcaatga tgaagagaaa
     4321 gatttgaatc aagaagcaag tgaaataata aaattatgca aagataatct agaagattat
     4381 aaaatccctg atcaatatag gaaggttaaa aatatcccgc acacttctac agggaaagta
     4441 aaacgtgata ggaataatta ttataatgaa tgagctatgt aaaaaatatg tttatcaatt
     4501 acaaaacgaa ctaaatcagt attgtgataa tctggaggga atccatgtta ttgcttacgg
     4561 ttcaaatggt agtaatgatt tgtctatttc atctgatttt gatgtttgtc ttattgttaa
     4621 cgatgattca tttgttgcta tgaatcagcg gttgatatgt gactttacaa agttatttca
     4681 ttttcaagaa aatttaccga tagataagga tattcctttg agcaacaaac ttatttatct
     4741 aagcagtgag gttgaattat ttttggataa tccgccgttc atatcagatt ctaagaaagt
     4801 taagattgaa gatattaaaa aaacgaagaa ctttttaact tcaagaacta tgaaacaacg
     4861 tctcttacta aatattttga ctacagattc tacagtttta tttggtgatg aagattatgt
     4921 taataatctg aaatataggg catgggagga cattgaaaaa ataattgaaa gagcgtataa
     4981 tattaaatta acgaccaaaa atgaaaatga attcttaaat ttactatatc aaaacccagt
     5041 atcgaaagca agtggagagt attatttagg atataaaaaa gaaaaaagga atgttgttaa
     5101 acatttagaa aggaatgttc accgattagc aattttgaac gagaaaaagg tggaagatat
     5161 aattgattta tctgaaaacg tcaataggtt actcttgaaa gattactcat ttttatttcc
     5221 ttctgaaact ataaaaaaaa tgataagcac atatccagaa aaaaaatcat gcagtattaa
     5281 agaagttttg tcttctaaat taacaatagc cagtaacaat ttcttgatta caaacggttc
     5341 tttagagggt atgaatatta taattgcgaa cttggttcaa aataatatag gatatttaac
     5401 ccctactttt tggggatatg gggattctgc aaaaaggtat aataaatcag tgatttcggc
     5461 acctttgtca gatatttata attataatgt tacagaaata gataaaattt ctaa
//
LOCUS       DAVLIK010000085         5204 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLIK010000085 DAVLIK010000000
VERSION     DAVLIK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5204
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.085"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(56..964)
                     /locus_tag="VXE87_002007"
     CDS             complement(56..964)
                     /locus_tag="VXE87_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0843485.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            1028..1297
                     /locus_tag="VXE87_002008"
     CDS             1028..1297
                     /locus_tag="VXE87_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0843486.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            1297..1677
                     /locus_tag="VXE87_002009"
     CDS             1297..1677
                     /locus_tag="VXE87_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0843487.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            1766..1993
                     /locus_tag="VXE87_002010"
     CDS             1766..1993
                     /locus_tag="VXE87_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843488.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(2033..2758)
                     /locus_tag="VXE87_002011"
     CDS             complement(2033..2758)
                     /locus_tag="VXE87_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV0843489.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            2920..4761
                     /gene="typA"
                     /locus_tag="VXE87_002012"
     CDS             2920..4761
                     /gene="typA"
                     /locus_tag="VXE87_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0843490.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            4781..5035
                     /locus_tag="VXE87_002013"
     CDS             4781..5035
                     /locus_tag="VXE87_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0843491.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT         1532 a          960 c         1152 g         1560 t
ORIGIN      
        1 aaaaagaacc aatgtgcagg ttgttgctag cctacatatt ggttcttatc atttctcaac
       61 tatcaaactg aacttcttct agtagatagt caataaagcg ttcgcccatc ttagataggc
      121 tggttttctc atgctggata tagaccagct caatcgggtc atcaatatcc agtgggatag
      181 aaacgatatt gtctccgttt aggttgctgt tcaaaatccc tgtcgcaatg gtataaccat
      241 ccaaaccaat caagagatta aagagggtgg cacggtcact gaccacaatg gatttcttgt
      301 ggtgttcttg agaaagaatc tcttctgaaa agtagaagga gttgtgcgtc ccttggtcat
      361 agctgaggta agggaaattc tccaaatcag acagtttcac cttgtctttc tttgccagag
      421 ggttggtctt gctgacaaag atatgcggtt gcgctgtgaa gagatggtgg gctagcaggt
      481 gattgtcatc cagcatcttg gttaaaacat cacggttgta actgtttaag aagaggaccc
      541 cgacctcact gcggaagttc ttgacgtcgt cgataatctc ccaagtccga gtttcacgaa
      601 ggaagagttc gtatttctcc atatcgcttt tcttgagcaa agagacaaag gcattgacca
      661 caaaggcata gtgttgagac gaaacgctaa agagttcgcg gtgggcaaca ggatttttat
      721 agcgttcctc cagaagctgg gtctgctcga caacctgacg ggcataagag agaaactcca
      781 tcccatcacg ggtcaaggta atacccttgg gattgcggat aaagatttca atgcccattt
      841 cattttccaa atctcgcact gcattggaga gactgggctg agtgataaag agttgcttgg
      901 ctgcctcatt catagagcca gtttcgacga ttttgataat ataatgtaat tgttgaattc
      961 tcatgttttt attgtaccac acttgcctta gaatcgccaa agaagatagg aaaataagga
     1021 gcattgtgtg agtctcttct tgaaaaaaac acaaaatttt gctagaatga gtcttatgaa
     1081 aacattctat gatgtgcagc aattcctcaa acgatttggt attattgttt acatgggaaa
     1141 acgcttatat gatattgaac tgatgaagtt ggaactatct cggatttacg atgcagggtt
     1201 gatggataaa ttagactatc tagaggcaga agcagttctt cgcagagagc acaaggtaga
     1261 attggattat attgagaaaa atggagaaaa gaactaatgg ttacttggat tttgtgggca
     1321 cttatactag caatgttggc gtggatgggc tttaactatc ttcgtattcg tcgtgcggct
     1381 aaaattgtgg acaatgagga gtttgaagcc ttgattcgta cgggtcaatt gattgatttg
     1441 cgcgacccag cagaattcca cagaaaacat atccttggtg cacgcaatat tccttcaagt
     1501 cagttgaaaa ctagtcttgc agcccttcgt aaagataaac ctgtccttct ctacgagaac
     1561 caacgtgcgc aacgagttac aaatgcagct ctttacttga aaaaacaagg tttttctgag
     1621 atttatatcc tttcttatgg cttggattct tggaaaggga aagtgaagac tagctaacct
     1681 tatttccaaa ttagtcgaat gataggatga agctattgtt ttatagtata attaatttgt
     1741 ataaaattta aggagttctt agaacataaa agaaaagaag aaaaatccac tttttgtggg
     1801 tatcttgtcg attattcttg gtttgttatt tccaattgta ggcctgattt tgggtatcat
     1861 aggattggtc ttggctattt cataccaaaa agagtcacaa ttagactata aaatagaaaa
     1921 gattcttaat atcttaggaa ttgtgatttc tgtagttaac tggattgtag caatcgcctt
     1981 aatttttcgg taaataaaag aaaaaagctt tagttttaaa gcttttttta ttttatcgac
     2041 tcatctctaa atagttttta atgatttgta actctttttg gttcaaaggg cggtagttac
     2101 cttctgctaa atctgggttc aatgtgaagt ccccaaattg gattctcttg aggctagtta
     2161 ccttaacacc aaccgagagg aacattttct tgatttgatg aaattttcct tctgaaatgg
     2221 tgatagaggc ttgactgagg gaaggacttg cagatagaat ctctagtttt gcgggtttac
     2281 agacagtacc atctaaaaag acaattccct tttgaaaggc ttggatatgg tcaggtgtta
     2341 gaagtccatt aacctcaact tgataagtct tatcgacatg atattgggga tggaggagtt
     2401 ggaagcccaa gggaccgtta tcggtcaaga gaaggagtcc tgttgtatct cggtccagtc
     2461 ggccgacggc atagagcttg tcagactgga tgtcagatgg aagcaggtcc atgacggtcg
     2521 gaagttcctt gtctttgttg gctgtaacga caccagcagg tttatgaagc ataagatagg
     2581 tgtgttcata gccttgaatg attcgatcct gaaaaaggag ttcttgtagt cctgtatcga
     2641 tattttgagc tagggagcgg gctgggcaac catcgactag aatttcccct ctgaggagtg
     2701 cttgcttcat ggcctttcgg ctaacttttt cttgggctaa taaattatct aaacgcatac
     2761 tgtgcctatc ttatcataag tcgcttgctt tgaaaaggct tgacgtgaaa agaaaagcgg
     2821 agtgaaaaca tttacacttg cttgagttat gttatttatt tgaaattatg gtataatcgt
     2881 tcagttagaa aataaatttt gaatattata gaggaaatca tgacaaaatt aagagaagat
     2941 atccgtaaca ttgcgattat cgcccacgtt gaccacggta aaacaaccct ggttgacgaa
     3001 ttattgaaac aatcagaaac gcttgatgca cgtactgaat tggcagagcg tgctatggac
     3061 tcaaacgata tcgaaaaaga gcgtgggatt accatccttg ctaaaaatac tgccgttgct
     3121 tacaacggaa ctcgtatcaa cattatggac acaccaggac acgcggactt cggtggagaa
     3181 gttgagcgta tcatgaaaat ggttgacggt gttgtcttgg tcgtagatgc ctatgaagga
     3241 accatgccac aaactcgttt cgtattgaaa aaagccttgg aacaagacct tgtcccaatc
     3301 gtggttgtta acaaaatcga taagccatca gctcgtccag cagaagtagt ggatgaagtc
     3361 ttggaacttt tcatcgagct tggtgcagat gacgaccagc ttgatttccc agtggtttat
     3421 gcttcagcga tcaacggaac ttcttcattg tcagatgatc cagctgacca agaagcgact
     3481 atggcaccaa tctttgacac gattatcgac catatcccag ctccagtaga taactcagat
     3541 gagcctttgc agttccaagt gtcacttttg gactacaatg actttgttgg acgtatcggt
     3601 atcggtcgtg tcttccgtgg tacagttaag gttggggacc aggttaccct ttctaaactt
     3661 gacggtacaa ctaaaaactt ccgtgttaca aaactcttcg gtttctttgg tttggaacgt
     3721 cgtgaaatcc aagaagccaa agcgggtgac ttgattgccg tttcaggtat ggaagacatc
     3781 tttgtcggtg aaaccatcac tccgacagat gcagtagaag ctcttccaat cctacacatc
     3841 gatgagccaa ctcttcaaat gactttcttg gtcaacaact caccatttgc tggtaaagaa
     3901 ggtaaatggg taacttctcg taaggtggaa gaacgcttgc aggcagaatt gcaaacagac
     3961 gtttcccttc gtgttgaccc aactgattca ccagataaat ggactgtttc aggacgtgga
     4021 gaattgcact tgtcaatcct tatcgaaaca atgcgtcgtg agggctatga acttcaagta
     4081 tctcgtccag aagttatcgt aaaagaaatc gacggtgtta aatgtgaacc atttgaacgt
     4141 gtacaaatcg acactccaga agaataccaa gggtctgtta tccaaagcct ttctgaacgt
     4201 aaaggtgaaa tgttggatat gatttcaact ggtaatggtc aaactcgttt ggtcttcctt
     4261 gttccagcgc gtggtttgat tggatactca actgagttct tgtcaatgac tcgtggttac
     4321 ggtatcatga accatacctt cgaccaatac ttgccattga ttccagggga aattggtgga
     4381 cgtcaccgtg gtgcccttgt ttctatcgat gctggtaagg ctacaactta ctcaatcatg
     4441 tctatcgaag aacgtggtac gatctttgtc aacccaggta ctgaggttta tgaaggaatg
     4501 atcatcggtg aaaactctcg tgaaaatgac ttgacagtta acatcacgaa ggcaaaacaa
     4561 atgaccaacg ttcgttcagc tactaaggac caaacagctg ttatcaagac gcctcgtatc
     4621 ttgacacttg aagagtctct tgagttcttg aacgacgatg agtacatgga agtaacgcct
     4681 gagtctatcc gtttgcgtaa acaaatcctt aacaaagcag agcgtgagaa agctaacaag
     4741 aagaaaaaat cagctgaata agagctagaa agagagaaag atggtctatt tagtcctagg
     4801 aattttactg ctcctactct atgtatttgc gacaccagaa agcattaaag ggactgtcaa
     4861 tatcgtcgct atggtatgta ttttagtggc actcttgatt ttattggttc tatcttttct
     4921 gaaaattttt caattaccaa cagaaatatt cctagcaata gccatgttga tcctagctta
     4981 ctttagtgtt agagacatca cactcatgcc agtcaaaaaa agtaaaagaa gataaaaaga
     5041 gagttttggc tctctttttt gctaggaatt ttacaagatt gcaatttatt tttgagttat
     5101 caccatctct tttgtttgga taatatgaat gggaaaaact tgaataaaat tctttaatgg
     5161 catctatttt atatttggtt agtactggtt gcatattatt ttga
//
LOCUS       DAVLIK010000086         5051 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLIK010000086 DAVLIK010000000
VERSION     DAVLIK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5051
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.086"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..278
                     /locus_tag="VXE87_002014"
     CDS             <1..278
                     /locus_tag="VXE87_002014"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEV0843492.1"
                     /translation="AEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFD
                     LKNGSLHELYEKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            280..489
                     /locus_tag="VXE87_002015"
     CDS             280..489
                     /locus_tag="VXE87_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843493.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            486..899
                     /locus_tag="VXE87_002016"
     CDS             486..899
                     /locus_tag="VXE87_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0843494.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLLASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIYYLST"
     gene            942..1229
                     /locus_tag="VXE87_002017"
     CDS             942..1229
                     /locus_tag="VXE87_002017"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843495.1"
                     /translation="MNKYKKLIELIENNGLEIQSKKCYDPQSAWHGEELWIVDKKKQN
                     KIFDLSGNGYCFHDAKVEEAIEEVEKYLLLKKMDTFDDFKKWVEKNAKPKK"
     gene            1370..1582
                     /locus_tag="VXE87_002018"
     CDS             1370..1582
                     /locus_tag="VXE87_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843496.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDL
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            1752..2336
                     /locus_tag="VXE87_002019"
     CDS             1752..2336
                     /locus_tag="VXE87_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0843497.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            2343..3188
                     /locus_tag="VXE87_002020"
     CDS             2343..3188
                     /locus_tag="VXE87_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV0843498.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            3200..3382
                     /locus_tag="VXE87_002021"
     CDS             3200..3382
                     /locus_tag="VXE87_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV0843499.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            3372..3560
                     /locus_tag="VXE87_002022"
     CDS             3372..3560
                     /locus_tag="VXE87_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843500.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            3562..3873
                     /locus_tag="VXE87_002023"
     CDS             3562..3873
                     /locus_tag="VXE87_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0843501.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            3854..4192
                     /locus_tag="VXE87_002024"
     CDS             3854..4192
                     /locus_tag="VXE87_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843502.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCINSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            4167..4682
                     /locus_tag="VXE87_002025"
     CDS             4167..4682
                     /locus_tag="VXE87_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0843503.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNAAIKVVQADAR
                     RLVPVNDGELITSIKTRAKMDGDRAIGEVYTNLKYAPYVEFGTGPKGQASHSGISPEV
                     SVTYKSHPWYVHEDQINVGSYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIQ"
     gene            4679..5047
                     /locus_tag="VXE87_002026"
     CDS             4679..5047
                     /locus_tag="VXE87_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843504.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDKEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
BASE COUNT         1738 a          822 c         1165 g         1326 t
ORIGIN      
        1 tcgcagaagg ttataaaatt gtaaaagtaa aaaacacttg gctagtagat ggaccataca
       61 aaggtgtgaa tacagtcgtt gaaaaagatg gtatcaactt tgaaatgcag tatcatactc
      121 aggaaagttt cgacttaaaa aatggttcat tacatgaact ctatgagaag tatcgtgata
      181 cgaatacatc tgatctagaa cgcatgaaat tatttaagga aatgcttgat ttaagcaatg
      241 ggcttgagat tcctaaaaat atagagaggg tgaagtgata tgaaagatat taaatactac
      301 cgcacaacga cgaacaatgc tcaagtactt cgtttgattg atggtgtcat gcaagttttt
      361 gacattgaaa aaaagtgggt taatagcatg gattggttta ataaaatctt ttttaatgac
      421 tttacggatt ttgaagaaat ttcagaaaat gatgcattta cttatattga caggatggta
      481 gcggcatgat tgatattgcc ttggctatcg ctaaaaaagc acatgcaggg caggtagata
      541 aagcgggtgt tgattacata cagcatcctc tctatgtggc cagtcaagtc aacactgaac
      601 aagaaaaagc tgtcgctctt ttacatgatg tgattgagga tagcgatata actgctgccg
      661 atttattggc gtctggtttg tcaaatgaag ttgttacagc ggtacaaatt ttgacaaaga
      721 aaaaaggtca aagttatcaa gaatatcttg ggaaagtaaa atcaaataat ttagcaagag
      781 ttgtaaaact tgcagatttg aaacataact cagatttatc acgtttgaaa tctgttacca
      841 atacagacta cgagcgtgtt aaaaaatata aaaatgcaat ttattactta agcacctaga
      901 gaaatctaag tgcttttttc gtgctcagaa aggagaatct gatgaataag tacaaaaagt
      961 tgatagaatt gattgaaaat aacggtcttg agatacaatc taagaaatgt tatgatccac
     1021 agagtgcttg gcatggtgag gagttatgga ttgttgataa gaaaaaacaa aataaaattt
     1081 ttgatttatc aggtaacggt tactgttttc atgacgctaa agttgaggaa gccattgaag
     1141 aagttgagaa gtatctatta ttgaaaaaga tggatacgtt tgatgatttc aaaaaatggg
     1201 tggaaaagaa tgctaagcct aaaaaatgat gcttagaaag gagtaaagac atgtttatat
     1261 gggattgggt atcaatcgcc tttgggtggt tggtattttt gttgttaata tttattatta
     1321 tggccgtaat cagcggaata attaaaggtg taaagaaagg aacagaaaaa tggaagaatg
     1381 gaaagaaaga tttaaaaaag aatactacga attgaaagaa cgattccaga agttagatat
     1441 gatgattggg aaatacgaaa aagggcaact agagtttgaa tctaaatgtc cgattgattt
     1501 gttaaaaggt cagcgttcaa ccatgtggaa ttatttaaga attctagaac aacgtgcaaa
     1561 aattgaagaa attaaactat aaaaattaac cgcatcgaaa tcgaggcggt tttcttatgc
     1621 tctaaccgta tggaatcccg tacggttttt atattgtcca aactgtgccg atgacattaa
     1681 aagctgtact gttccgtcgc cggacgtaaa acgagattat cgagtggcga cgtaatcgct
     1741 ggaggacaat tatgtcagaa gaaatcaatg caactgtatc tactgaatca actgagactg
     1801 tcgacactca aggaaatgtt gattcagtgc aggaagaaaa gcacgaacga actttcactc
     1861 gtgctgaaat cggtaagatg ctatctgccg aacgctctaa atgggaagct gagcaagaag
     1921 ccaaggaaaa cgaagctaag aaacttgcca agatgaacgc tgacgagaaa caaaaatatc
     1981 agttggatca gcgtgagcaa gaactagctg accgtgagaa ggctattgct cgcaaggaat
     2041 tgaccgcaga agctaaagca atgctaagtg aacgtgactt acctgttgag ttagtaaatg
     2101 tagttgattt gacaagcgca gagacggtat cgcagtctgt cgctgtattg cagaaatcat
     2161 gggagcaagc cgtgcaaaaa ggcgttcaag aaaaactaaa aggcggagct ccaatgaaac
     2221 aagcgccagt cgatagtgac ggtatcacaa aagaagaatt tgctcgtatg ggttatcaga
     2281 gtcgaaatga gctctatcaa aagaacccag agctttataa gaaattgaaa ggataataga
     2341 aaatgacagc aggacaaact aaattagcca ctatggttaa tccagaagta atggcggata
     2401 tggtagccgc taaattacct aaattgatta aatttacacc gctagcgtat gtagagacaa
     2461 agcttgaagg tcaaccaggt agcactttaa cagtgccagc atgggagtat gcaggagacg
     2521 ctactgaaat tgaagaaggc caagcaatta cgccagacca attgactact aaaaagacta
     2581 ctatgaccat caaaaaagca ggtaaaggtt atgaaattac cgatgagtct cttttgtcag
     2641 gtcttggtga cccactaggt caagcgactt accagcttgg tttagctatt gccaacaaga
     2701 tcgataatga tttggtagcg gtagctaaaa ctgcaacaca acatattaca gaaactccaa
     2761 caactcttga ggcaatcgat aaagctctag atatctttga ggacgaagaa gatgcacagt
     2821 atgttgctat catcaaccct aaagatgcta ctaagctaaa aactgcagta gcaaaagaat
     2881 ggattaaagg ttcagagctt ggagcaaata tggttgtttc tggaaccttc ggtgaagttg
     2941 atggtgtgca aatcgtgcgc tctaaaaaag ttgatgaagg taaaggcttc cttgttaaag
     3001 tgtcaccaag tcaaactcag acagacgacg ctaacaaata tggagctttt gttatcttgc
     3061 ttaaacgtga tgtggctatc gaaacagacc gcgatatctt gaagaagact accgtaatca
     3121 caggtgatga acactacggc gtttaccttt acgaccctac acgagttgta aaattcggtg
     3181 gcgcgtaaga ggtgacgata tgagtttatt gctacgacgt cattatattc aagaagagca
     3241 ggttaaccag tattctgatt tagagaataa aactctagaa gagttgaagg atctagcgaa
     3301 agaagcaggt gtagcaggcg cttataagtt gacaaaagcc gaaattgtag aagttttgga
     3361 ggaactaaaa agtgaaattt aaaatcaaac aagatttcta tgattgggaa tcaaatgtga
     3421 aacgactggc aggagaggaa cttgagatta ctgaggagcg ctatgctgag ctggctgaca
     3481 atattgccag caacggtgtc actatctcag acgttcttga gaaaatcctc cctgaacctg
     3541 agttcttaga agaggattga tatgtctata gagttgctga agaaattaac aggcgaagaa
     3601 gatactcagc ttctcatgtt gctccaaacg agggctacaa atcttatctt gtcagagact
     3661 aatcgcacat ctttgacacc tgctttaagt cttttgatac ctgaggttgc tatcgagctc
     3721 cacaaccgct caggagcgga aggagagcat tctagaaccg agggtggtat agcagtagtc
     3781 tacggagaaa acggcctatc tacgggtctt ctacagcgaa tacgcatgca caggctagca
     3841 agggtggcag gtcatgtttt tgaagcagag tagactgaaa ccctatccaa tgcgacggtt
     3901 tgaaaagact gtcactgagg aaggtgtcgc gaaagaaggg tatgccaagg aagctgagac
     3961 agtccgcctt gaattgtggc cagctagtag caagctacaa tctgaattgt atggcgagcg
     4021 tgtcaatgat attttgaacg caaatgccaa caagtcagct actatcaaag taaaagatgg
     4081 tgtgtgtatc aatagtcaga cggaagtgac tcatagggtt atttctaaaa aggtctacac
     4141 acatcatcaa gttttggagt tagagcgtgt cagggctact aggggcagat aggcttatag
     4201 ctaaatgtag acggttagct agtaaaaaaa ctggcgagga tatcgtctta cgtgcggtac
     4261 acaatgctgc tataaaagtt gtccaagctg atgcaagaag actcgtacca gtgaatgatg
     4321 gagaacttat aactagtatc aaaaccagag caaaaatgga cggagatagg gctataggcg
     4381 aagtttacac caaccttaaa tacgctcctt acgttgagtt tggaacggga cctaagggtc
     4441 aggctagcca ttctggtatc tctccagagg tcagcgtgac ttacaagtct catccttggt
     4501 atgtgcatga agaccaaatc aatgtaggat cttaccactt tcaaaagatt ggggagtttt
     4561 acaagatgta tggtcaacct gctcagcctt atctttatcc agctttgaga gacaatcaag
     4621 agcgtgtgtc taagaatatt tcgaattatg tccgtagaaa gataagagaa caaatacaat
     4681 gatcaatatc aagcctgtta tttataaaga attgcaaaag gttgcagata atgtgaccga
     4741 tacttatcct agcgattggg agactttccc agtcgttatt tttttagaag aacaaaacaa
     4801 gccaggtgat tggtttgacg acaaggaaca aaaatcctct atccgctata aggtggatat
     4861 ttttgatgat accagcacta gtgagttagc tgttaaaatc aatcagattt ttgagtcttt
     4921 aggtttgcga agaaccgact gccaagacgt gccagacccg tctcatttga gacataaggt
     4981 catgcgtttt gaaggtgtcg ttgacttaga ttcagagctt gtttttcaat ttagaatgga
     5041 gaattaaaat a
//
LOCUS       DAVLIK010000087         5015 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLIK010000087 DAVLIK010000000
VERSION     DAVLIK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5015
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.087"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..526
                     /locus_tag="VXE87_002027"
     CDS             <1..526
                     /locus_tag="VXE87_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0843505.1"
                     /translation="EDYCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTR
                     KAQGRHLEQEGNIKHALIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQT
                     LMESLSDDDYDFAFDEALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYE
                     CYSPLNNLELDDFE"
     gene            complement(693..764)
                     /locus_tag="VXE87_002028"
     tRNA            complement(693..764)
                     /locus_tag="VXE87_002028"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(729..731),aa:Arg,seq:cct)
     gene            complement(806..1153)
                     /gene="rplS"
                     /locus_tag="VXE87_002029"
     CDS             complement(806..1153)
                     /gene="rplS"
                     /locus_tag="VXE87_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0843506.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1272..1601)
                     /gene="crcB"
                     /locus_tag="VXE87_002030"
     CDS             complement(1272..1601)
                     /gene="crcB"
                     /locus_tag="VXE87_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0843507.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1595..1969)
                     /gene="crcB"
                     /locus_tag="VXE87_002031"
     CDS             complement(1595..1969)
                     /gene="crcB"
                     /locus_tag="VXE87_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0843508.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(1966..2232)
                     /locus_tag="VXE87_002032"
     CDS             complement(1966..2232)
                     /locus_tag="VXE87_002032"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0843509.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMRLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2348..2791)
                     /locus_tag="VXE87_002033"
     CDS             complement(2348..2791)
                     /locus_tag="VXE87_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0843510.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2895..3830
                     /locus_tag="VXE87_002034"
     CDS             2895..3830
                     /locus_tag="VXE87_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0843511.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3884..4168
                     /locus_tag="VXE87_002035"
     CDS             3884..4168
                     /locus_tag="VXE87_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0843512.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4225..4443)
                     /locus_tag="VXE87_002036"
     CDS             complement(4225..4443)
                     /locus_tag="VXE87_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843513.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREVFKKMNSTWTINESMVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(4440..5015)
                     /locus_tag="VXE87_002037"
                     /pseudo
     CDS             complement(4440..5015)
                     /locus_tag="VXE87_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1592 a         1067 c          873 g         1483 t
ORIGIN      
        1 ggaagattat tgtaaagaaa aaaacaatat ctcttttaaa gcaacttttg gtgatataaa
       61 atggagtctc ttaaataaac aagctcatag gaatactgta tcaggagatt ttggatgctt
      121 atctaacaca cgaaaggctc agggaagaca tttggaacaa gaaggtaata ttaaacatgc
      181 tttaatatat tacatagaat ctttgataat tactatttca ggattagaaa acaatttttc
      241 agccactgat tatccagtat attatcccga ttcgatacct gactactcac taaaacatat
      301 tcaaacatta atggaatcat tatctgatga cgattatgat tttgcttttg atgaagcatt
      361 atttcgcttc tcaattttga atgcaaatca ttttttatct aaggaagata ttgactattt
      421 aagagttaat ttacctcgtt ccactgctga agaaataaac aattacttaa agaaatatga
      481 atgttatagt cctttaaata atttagaact tgacgatttt gaataaattg actatacaaa
      541 catttatata ctcgatatag tctcaatttt atctgatgat tgcccaaatt tttcaataat
      601 aaaacgcata atattatgga gacaatcccc tatattatgc gttcttttaa tatcaaagac
      661 tttttgacaa acttctttga tatctaatta catgccccct gcaggaatcg aacctgcaac
      721 tactccttag gagggagttg ttatatccat tgaactaagg gagctagata aaaactctgc
      781 tgaaaagcag agttttttag tcgaattaac gacggatttc tttgatacga gctgccttac
      841 cttgaagagc acgcaagtag tacaatttcg cacgacgtac tttaccgtaa cgaacaactt
      901 cgattttttc aacacgtgga gtgtggattg ggaagatacg ctcaacacct acaccgttag
      961 agattttacg aactgtgtag ttttctgaga ttccagcacc tttacgtgcg ataacaacac
     1021 cttcaaaaat ctggatacgt tcacggttac cttcgacaac tttcgcgtgt acacgaacag
     1081 tgtcaccagg acggaatgat gggatatctg tacgaagttg accttcagtc aagctttgga
     1141 ttaatggatt cattttattc tcctatcttt gtcaatcttg aggaaacttc ctcagcggat
     1201 aaactgtatt cttgtgcgtc cattacacac aagatacagt ttaccaaatt ttcacaaaaa
     1261 agtaaagaaa tttatagcaa aattcctaaa aaaatcgcaa ccaaaccacc tatgtaagtc
     1321 aaagtcaggt aagaataaaa gaccttctta tcacttagca gtctttgaag ttcgtcattc
     1381 aaggtcgaaa aagttgttaa accgccacaa aatcctgttg ctagaatagc atatacttcc
     1441 ttagactcta catgattgta gaatactcca attaaaaaac aacctaaaag attagctatg
     1501 agcgttccga gtggcaattt agaagcttga ttatagcgag aaaagaaata ccgtacgagt
     1561 gctccgaaac cacaagcaat tgcaagatag acaattacca tttcttcctc cctagaaaat
     1621 aagctaagag taggcctcca ccgatgctca aaagcaaata caggactaaa ctaaaataac
     1681 gccctgtatc aagcagcttc acagtatcaa gcattaggct ggaaaaagtt gttaaacctc
     1741 cgcaaaaacc cgtccccagt gctaaaatca agcccttact agtcccctta tagaccagat
     1801 agcccttgac aagaaaaatc aagcagaaaa ttcccagata gttgacaaag agagtgcccc
     1861 aaggaaagtc tggactggct ggtaaccagg tggaaactag atatcggaca agtccgccca
     1921 acatagcagc tagaaaaatt cctagcggat aaaattgttc ttttttcatt tgatattttg
     1981 atcctgataa tcacgcgaac gtttgagtat gtccgaaaaa gtcgctacaa tagtctcctg
     2041 atagcgcttg tcctctacac gactcccaac cttttcaaaa ataacttctt ctctcttagt
     2101 atctaaaatc ggtttacctg aagctttctt ataagcaacc accccctcaa ctaaacgcat
     2161 tcgttcttct aacagtttga caatttggtc gtcgatttga tcgatttctt gacgaataat
     2221 atctaaatcc atacagtctc ctcctttatt tgaattattg tatcaaaaag ccatcaatta
     2281 ggctagtaaa atcccaactc tcgataagaa aaatgcactg attgattaca tcagcgcact
     2341 tttatgctta tcctacttta gcagccaatt cttctgcgaa ttgttccaag cgttcaatat
     2401 cttcttcctc ggcagaaaga tcaactttaa cacactctga acctttttct gctcctgttg
     2461 acacaaagac acggtcaaaa tcatcaacag ccttacagaa ttcatcgtag aaggtatctc
     2521 ctgagccgac cactccatag attttgccat tcaagttgag atctgctagg tcttcgtaga
     2581 agtccatcat ctcatctggc aattcaccat caccataagt ataggtcgca acgatagcga
     2641 tgtctgcttc caagaagtct gaagcgtcaa cagttgtaca ttcatcaaca tcaacatcca
     2701 agcccaagtc acgtaatttg tctgctacaa tatctgcaat ttcttcggta ttaccggtca
     2761 tactggcaaa tacaattttt gctaatgcca tatcgtcctc ctcaatttat ctttctccat
     2821 tatatcacat ctttttcatt ttaaaaataa aaattcttgt gctacaatga aatgagaaag
     2881 aattgaggtt atttatggag atttgccaac aaattttaga aaaaattaaa gaatacgaca
     2941 ccattatcat tcatcgtcat atgaaaccag accctgatgc cttgggaagt caggtgggat
     3001 tgaaagcctt gctggaacat catttcccag aaaaaaccat caaagccgtc ggttttgatg
     3061 aaccaactct tacttggatg gctgagatgg atcttgttga agatagagcc taccaaggcg
     3121 cacttgtcat cgtctgtgat acagctaata ctgctcgtat cgatgataag cgctatagtc
     3181 aaggtgattt tctcattaag attgaccacc atccaaatga tgatgtatac ggtgacctgt
     3241 cttgggtcga tactagttca agtagcgcta gcgagatgat taccctattt gcccaaacaa
     3301 cccaactagc cttggcagat cgcgatgctg agttgctctt tgcaggaatt gtcggtgata
     3361 caggtcgctt cctctaccct tctaccactg cacggactct tcgcctggct gcttatttga
     3421 gagaacataa ctttgacttt gcggctctca ctcgcaaaat ggacactatg agctacaaaa
     3481 ttgctaaact gcaaggctac atctacgacc atctggaagt ggatgaaaat ggtgctgctc
     3541 gcgttatcct gagtcaagaa gtcttgaaac aatacaatgt aaccgatgct gaaactgcag
     3601 ccattgtcgg tgcacctgga cgcattgaca gagtgagtct ctggggaatt tttgtcgaac
     3661 aggctgatgg ccactaccgc gttcgcttac gcagtaaaat ccatcctatc aatgaaatcg
     3721 ccaaggagca tgatggtgga ggccaccctc tagcaagtgg tgctaattcc tatagcctag
     3781 aagaaaacga aatcatctac caaaagttaa aaaacttgct taaaaactga taaaatactt
     3841 gccaaacttt tcagaatctg atagactagt atggtaacaa tctatggctc gcaaagagac
     3901 catggcagaa aggaaatatt gcaaaatgaa aaaagatatc catccagaat atcgcccagt
     3961 tgtcttcatg gacacaacta ctggttacca attccttagc ggttcaacaa aacgctctaa
     4021 cgaaacagtt gagttcgaag gcgaaactta cccattgatc cgtgtggaaa tttcatcaga
     4081 ctcacaccca ttctacactg gacgtcaaaa gttcactcaa gcagatggac gcgtggatcg
     4141 tttcaacaaa aaatacggtc tcaaataatg ataagagaac agtttcggct gttctttttt
     4201 gtttcttgaa atcaactgct gttttcatgt tccagactca tctgtaggtt cggtttccat
     4261 gctactaggc aggaaggaaa tagctgtttc aacacgtcca taatgagctg tactattgtc
     4321 acgaaccata ctttcattga tggtccaagt ggaattcatt ttcttaaaaa cttctcggac
     4381 tttttccaaa tctttggagg caatggcctg ctctaaggtt tcaaaacgag gacttatact
     4441 catctgcttt caaaaagcat tctagtccat ctccgattaa cgatggactt tatcacctcc
     4501 ttctccagtc cttgtataac atcttggagt tgattcatga catcttccaa agtttaaaag
     4561 gctttattct taaatccacg tttacgaatc tctttccaca cttgttcaat ggggttcatc
     4621 tctggtgtgt atggaggaat aaatgcaaag ccaatattag tcggaatctt taaggtactt
     4681 gatttatgcc atatagcatt gtccataacg agtaaaagga taagcttgtg aaagctcttc
     4741 taaaaaggcg ttcatccaca ctccttttta taagcctgaa ataaggcatc aattgtaaca
     4801 aattctcctg cctctgtagc cttcaaatga cgggcaagaa aggctttctc ttcctcaact
     4861 gtcatatatg catggttacg accaccacgt gtttcttgaa ggagagagtc gagtccgaac
     4921 tcctcatatt tttttacatt tcgctaaatc gttgtttgat tacagtctaa aagctctata
     4981 atctctttat aagatttgcc catcagacga aatat
//
LOCUS       DAVLIK010000088         4975 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLIK010000088 DAVLIK010000000
VERSION     DAVLIK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4975
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.088"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            293..1579
                     /locus_tag="VXE87_002038"
     CDS             293..1579
                     /locus_tag="VXE87_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0843514.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            1594..1905
                     /locus_tag="VXE87_002039"
     CDS             1594..1905
                     /locus_tag="VXE87_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843515.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            2165..2893
                     /locus_tag="VXE87_002040"
                     /pseudo
     CDS             2165..2893
                     /locus_tag="VXE87_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            3329..4120
                     /locus_tag="VXE87_002041"
     CDS             3329..4120
                     /locus_tag="VXE87_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843516.1"
                     /translation="MNFALNKGEIVGLAGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQEIFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSEFFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            4136..4864
                     /locus_tag="VXE87_002042"
     CDS             4136..4864
                     /locus_tag="VXE87_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0843517.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLGFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
BASE COUNT         1596 a          779 c          979 g         1621 t
ORIGIN      
        1 ctagactgta tcaatccttt tccattatag gagcaacaga gtgggagtag tcatctaagg
       61 actaatttat gtatttttac gagtcagtat ctttggatac tggtttttac ttttctagac
      121 tttttgacta cttgttaaaa ctgggataat tttcgactgt ttaacagtta ttatgcaaag
      181 tctaaaagat tagaattgtc aaaacaatcc gtctaggctt gattttatcc tttatttact
      241 ataaaatgag aaggaaaaat gtcaaacttt tatattgcaa ataggagaaa tcatgacaaa
      301 aacattaaaa cgtcctgagg ttttatcacc tgcaggaact ttagagaagc taaaggtagc
      361 tgttcagtat ggagcagatg ctgtctttat cggtggtcag gcctatggtc ttcgtagccg
      421 tgcgggaaac tttactttcg aacagatgga agaaggcgtg cagtttgcgg ccaagtatgg
      481 tgccaaggtc tatgtagcgg ctaatatggt tatgcacgaa ggaaatgaag ctggtgctgg
      541 tgagtggttc cgtaaactgc gtgatatcgg gattgcagca gttatcgtat ctgacccagc
      601 cttgattatg attgcagcga ctgaagcacc aggtcttgaa atccaccttt ctacccaagc
      661 cagtgccact aactatgaaa cccttgagtt ctggaaagag ctaggcttga ctcgtgtcgt
      721 tttagcgcgt gaggtttcaa tggaagaatt agctgaaatc cgcaaacgta cagatgttga
      781 aattgaagcc tttgtccatg gagctatgtg tatttcatac tctggacgtt gtactctttc
      841 aaaccacatg agtatgcgtg atgccaaccg tggtggatgt tctcagtcat gccgttggaa
      901 atacgacctt tacgatatgc catttgggaa agaacgtaag agtttgcagg gtgagattcc
      961 agaagaattt tcaatgtcag ccgttgacat gtctatgatt gaccacattc cagatatgat
     1021 tgaaaatggt gtggacagtc taaaaatcga aggacgtatg aagtctattc actacgtatc
     1081 aacagtaacc aactgctaca aggcggctgt ggatgcctat cttgaaagtc ctgaaaagtt
     1141 tgaagctatc aaacaagact tggtggacga gatgtggaag gttgcccaac gtgaactggc
     1201 tacaggattt tactatggta caccatctga aaatgagcag ttgtttggtg ctcgccgtaa
     1261 aattcctgag tacaagtttg tcgctgaagt ggtttcttat gatgatgcgg cacaaacagc
     1321 aaccattcgt caacgaaacg tcattaacga aggggaccaa gttgagtttt atggtccagg
     1381 tttccgtcat tttgaaacct atattgaaga tttgcatgat gccaaaggca ataaaatcga
     1441 ccgcgctcca aatccaatgg aactattgac tattaaagtc ccacaacccg ttcaatcagg
     1501 agacatggtt cgtgcattaa aagaaggact catcaatctt tataaggaag atggaaccag
     1561 cgtcacagtt cgagcttaag aaaggaaaag gaaatgatag aggcacaggg tttcttagtg
     1621 gataagcaaa caagatgcat tcattaccat agcaagctgg atattattgc tttacaatgc
     1681 tatgattgta aaaagtatta tgcttgttat cggtgtcatg attcattaga aaatcaccct
     1741 tttgagcctt atcccttatc tttgatacag gataagccta ttttatgtgg tgtttgtcta
     1801 aaactattaa catataagca atataaagaa agcttaagtt gcctcttttg tttttctcgc
     1861 tttaatccag gttgccaaaa tcataaggaa cgctatttta aatagcaaat catctagttt
     1921 tgaagtagga gaaaactcaa ttccaagaga aaatgaagta aatcttccca caataaaacg
     1981 cataatatca agattgttca atacctgata ctatgcgttt ttaagatttt aaagactttt
     2041 ttcctagccc ctttttactt tatctggtat tttgactact tgttaaaact ggggtaattt
     2101 tcgactgttt aacagttatt atgcaaagtc taaaaggtta gaattgtcaa aacaatccgt
     2161 ctagagtatg cgtgatgcca accgtggtgg atgttctcag tcatgccgtt ggaagtacga
     2221 cctttacgat atgccatttg ggaaagaacg taagagtttg cagggtgaga ttccagaaga
     2281 attttcaatg tcagccgttg atatgtctat gattgaccat atctcagata tgattgaaaa
     2341 tggtgtggac agtctaaaaa tcgaaggacg tatggagtct attcactatg tatcaacagt
     2401 aaccaactgc tacaaggcgg ctgtggatgc ctatcttgaa agtcctgaaa agtttgaagc
     2461 tatcaaacaa gacttggtgg acgagatgtg gaaggttgcc caacgtgaac tggctacagg
     2521 attttactat ggtacaccat ctgaaaatga gcagttgttt ggtgctcgtc gtaaaatccc
     2581 tgagtacaag tttgtcgctg aagtggtttc ttatgatgat gcggcacaaa cagcaactat
     2641 tcgtcaacga aacgtcatta acgaagggga ccaagttgag ttttatggtc caggtttccg
     2701 tcattttgaa acctatattg aagatttgca tgatgccaaa ggcaataaaa tcgaccgcgc
     2761 tccaaatcca atggaactat tgactattaa agtcccacaa cctgttcaag ctggagacat
     2821 ggttcgagct cttaaagagg ggcttatcaa tctttataag gaagatggaa ccagcgtcac
     2881 agttcgtgct taatgtagtt gtttagtttt aaaaaattat gcaaagctcc atatacaaca
     2941 cttaaacgag attaaagaat ggcgaaatcc cttgatgcgc aagagattag ctgtcctttt
     3001 ttatttttta agtgataaag tcggagctta ggtattaaag cctatcaaat taaacaaaga
     3061 agcgatgtct tagatatttt gaaaaaaatt aataagcaga aaactctcta ttattttgtt
     3121 gtagagagtt ttttgttaat aaaattttac aaaatgacat ttatatattg cattaagtta
     3181 gatatatgat ataatattgt taaaaagagg tgcaactttt taaactcaat aagaatcaaa
     3241 gagcaaacca tgaatattaa tggaggaata aaaaatgtaa gttataaatg taagtaagca
     3301 ttatggttat tcaatcattc tcaaagatat aaattttgca cttaacaagg gtgaaattgt
     3361 tggtctagca gggagaaatg gagttggtaa gagtacgttg atgaaaattc ttgttcagaa
     3421 taatcaaccg acttcaggta atattataag cagtgataat gttgggtatt taatcgaaga
     3481 accaaaatta tttttatcta aaacaggttt agagaattta aaatatttgt caaatttata
     3541 tggtgttgac tacaatcaag aaatatttag aagtttgatc caagagttag atttgactca
     3601 gtctattaat aaaaaagtaa agacctattc tttgggtaca aaacaaaaat tagctttgct
     3661 tctaactctc gttacggaac ctgatatatt gattttagat gaaccgacta atggtttaga
     3721 tattgaatca tcacaaatag ttttagcggt tctaaaaaat ttagctttac atgaaaatgt
     3781 gggaatttta atatcgagtc ataaattaga agacattgaa gaaatttgtg agagagttct
     3841 tttcttggag aacgggcttt tgacatttca aaaagtagga aaagatagtc ataatttctt
     3901 gtttgagata gctttttcat cagctacaga tagagacatt ttcattacca aacaagaatt
     3961 tggggatatt gttcaggaag agggactgag aattactatg tctgggaata ttcaaagtag
     4021 tgagtttttt aaatttttta acgaaaactc tattaaagta gttgattttg aaactaaaaa
     4081 agagacgctt aaagatattt acttaaatcg ttcaaaataa aggaaggtta taatcatgaa
     4141 attaaataaa ttgaattttc ttaaggaaaa tataagaaat ttatattcat caggcgtaat
     4201 atatctcagt ttgcttatct cgtttatacc gccgatattg cttacattct ttattctaaa
     4261 gactcaaggg acatcgcttg gtattaagca tatttcaaac ttttatgcta tgctcggtat
     4321 gttaatggct gttatacatg ctaatcgagt cattagtaga gatttttccc acaatacggt
     4381 aagtttgttt tataatcaac agaagaatcg gatgatttac gtcttgtcta attttctata
     4441 tgccatctca gtttccatta tttatgcttt gaatggcatt gtgttactag tcatcgtaag
     4501 taaattgggt attccaggtg atttaggatt agattttata gtagctattg tagtcaatac
     4561 aattttgtta gtcctgtttt attttctatt atcctacatt ttctatttat acaaattgaa
     4621 aagtggcttg ggatttggta ttttagtagc tttactactc tttatcccta atatattaaa
     4681 tacgatgatg atgaatacta gtaatgattt gtttatcaaa gcaattgaac ttcttccttt
     4741 ttattcttta cctgtatttg tggcttcaaa tacgatgtct attagtcagt atcttgtggt
     4801 aatcactaca atcattttat tgtacttttt cactctcaag aaaagcaaga agtattcatt
     4861 ttagtttcat ttagtattat tttgcatacc taaaatacaa taaaaaaatc agtcatcttg
     4921 gtatgctcct gctttcacta ttcaacacgt ttttgactta tactaggctc atttc
//
LOCUS       DAVLIK010000089         4846 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLIK010000089 DAVLIK010000000
VERSION     DAVLIK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.089"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(177..1592)
                     /locus_tag="VXE87_002043"
     CDS             complement(177..1592)
                     /locus_tag="VXE87_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0843518.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1605..3443)
                     /locus_tag="VXE87_002044"
     CDS             complement(1605..3443)
                     /locus_tag="VXE87_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0843519.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     MKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3461..4300)
                     /locus_tag="VXE87_002045"
     CDS             complement(3461..4300)
                     /locus_tag="VXE87_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0843520.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4600..4782)
                     /locus_tag="VXE87_002046"
     CDS             complement(4600..4782)
                     /locus_tag="VXE87_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0843521.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
BASE COUNT         1624 a          938 c          635 g         1649 t
ORIGIN      
        1 ataacccatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
       61 attaatcccc ctataaaata aagaggttta gaatttgatg tcttccaaac ctctttattt
      121 catatttaat gagatgttgc cttaaccgtg ataatatcta atcatcaata aacaaactat
      181 ttgaataagg attctccatt tgattcaatc actcctttat accaagtaaa ggacattttc
      241 ttatatcgat tgaatgtgcc atttccatca tcatttcgat caacataaat gagaccgtac
      301 cttttagaaa gttgtgcagt ggacatagaa acgcagtcaa tacatcccca agatgtatag
      361 cccataattt caacaccatc ctgtagagct tcagcaactt gcaataaatg ttctttcata
      421 tactgaattc tataatcatc ttggacggtt aagttattaa gttcatcttt tattagttga
      481 tctttagcac ctaatccatt ttctactata aataatggga tttgataacg gtcataatat
      541 ctatttaaaa ttatacgtag tccaattgga tcaatttgcc atccccactc tgaagactct
      601 aaataaggat ttactaaacc accaataata ttcccttctc ctgaattata ctgtgttgga
      661 agagcagatt gagtcacact catgtaatag ctaaaggata aaaaatctac ggtataattt
      721 tttaataact ctgcatcttc agctgcaaac tctatgttaa tgtcatgttc cttaaaatat
      781 ctttttgcat aattcggata ataacctcta acatgcacat ctgaaaatag ataatttaga
      841 ttctcatact catgagtcgc ccatacatct tttggatttg gagtcattgg ataagctggc
      901 atagctaata ccatacaccc caccttaaac tctgaattaa tctcacgagc aatttttgta
      961 accaaacttg aggcgactaa ttcatgatgt atagcttgat ataattcttg tttcgaaaga
     1021 ttctccttag gtatatctat tcctccacta gtaaatggta attccaaaac agagtttact
     1081 tcgttaaatg taagccaata tttaacttta tctttatacc tttctaaaac tgttcgagca
     1141 aatttttcat aaaaatgaat cattctccta tcaacccatc catgatattt tcttgctaaa
     1201 tataatggag tctcatagtg tgaaagagtt acaagtggct ctatcccgtg agcatgtagt
     1261 tcatcaaaca attcatcata atatttcaaa ccagcttcgt taggttcttc ttcatctcct
     1321 tttggaaaaa ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc catttcagaa
     1381 aacaaggata tatcttcctt atatttatga taaaaatcaa tacctatcaa ttttaagtta
     1441 tcttctgtag gattttctgt tgcttctcct aatccacctt tgggtaacac atcctgaact
     1501 gataagccct taccatcttc attatatgct ccctctactt gattagctgc aacagctcca
     1561 ccccaaagaa aatcatctgg aaaaatggtc ataactttcc tccattataa tattaccagt
     1621 aattccttag aatgctcgat tgtctgatta ttaggtaata ctaatacatc tagaaaatca
     1681 ttggtattcg ttacaattac tggtgtaact gtttcgtagc ctttagtctt gattaaattc
     1741 aagtccattt caaaaatcaa ctgatttttg aaaactctgt ctccttcttc tacatgacta
     1801 ataaaacctt gaccttttag ctcaacagta tctaatccaa tatgaattag taactcaaca
     1861 ccctcatcac tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt aattttccca
     1921 tcaaatggtg cataaacctt accttcactt gggataatcg ctactccgtc tccaattagt
     1981 ttatctgaaa atgttttatc ctggacatcg cttaacggaa tgatttctcc tgatatagga
     2041 gaaaatatca tttttttatt tgaaactcca gctttaactt ctaaattact agaactctct
     2101 tcttcatcga ttccaaatat ataagctaat acaaaggtaa taacaaccga aatgaccgcc
     2161 acaattaaag catttacaat atttgatggt acatcagaat aaataaattg aggcaacgct
     2221 atcaaagatg ggacagcaaa tagatacgct ttaacactag taagacctgc aaataatccc
     2281 gctaatccac caccaatcat agctgcataa agcggttttt tatattttaa agtcacacca
     2341 tataatgcag gttcggtaat tcctgcaagt aaggctgaga aacctgctgc aaaagcaatt
     2401 tgttttgtat tattattttt actctttaat gcaacagcca tcgaagcagc cccttgagct
     2461 aagtttgacc ctaacattgc tggaagaatt aatacgtctg gagtagcaat agatgccgcc
     2521 aaaaaaatag gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg cataatagca
     2581 ccaagaatag ctaatgtaag ccatccagct acaccataca tttgcccaac tagatttgat
     2641 aatccttcac caacaattac tccaataggt ccgactacaa ctaaggcaat acagcttgat
     2701 actaataata ctagcgtagg ttgcaaaaaa ctcttagtaa cagctggtgt taatttagca
     2761 atcatttttt caatatattt catcaaccaa accataataa gaattggaac gactgacgaa
     2821 ccataactag ctggtgtcac aggtacacca aataaactaa gaggattccc tgattgcacc
     2881 atttgaacaa aatttggatg gagaagtaca cctgctacag acatagctaa tgtagatgtt
     2941 acttttaatt tttgtgatgc agaataagct aataacagcg gtaagaaata atatggcgca
     3001 tccccaaaaa atgtcaaaaa agcaatagtc tgagaatctg attgcaatat accaagcatt
     3061 ggtaaaataa ttaccaagac tttcagcata cctcccccta acattgctgg aatgattgga
     3121 gtcatggaac cagcgatata ctcaatgatt ctttctaaaa tattcccttt gtgcccttga
     3181 acaactgaat cggattcaaa attgccaagt ttaacgaatt ctttataata attagctaca
     3241 tcattaccaa gtataatttg atattgtcca ttctttttca taatacctat tacacctggt
     3301 atcttcttca tatcatcatc attgactaaa ttttcatctt ttaattctaa tcttaaacgt
     3361 gttacacaat gggtaactct attgacattt ttttcacctc caattacatc gaggattttt
     3421 tgtaccttat ctttataact catggtattc tcctattcta ttaatctaaa ttttttgtta
     3481 agcgacgaat atgagccatc aaataaacta attcactaga agtcagcaaa taattgtact
     3541 cagtttgtat aaacattgcc acctgttcac cacattcata ttctctagga tatttatttt
     3601 tcattaatgc taacaagtct tcatcatcat cgtcacaata agttgtattt tcaaccaagc
     3661 gatgggcaaa taattttata tgagttatga atctataata atcaatagaa tcttggttaa
     3721 actcagtaca atagaaatct tgaatgattt tctcaattcc cataattatt tcagtgattt
     3781 tatacgactc ttgaaaatta ttttctaaat tagcattaac aaaatgtagc gctatgaatg
     3841 cagcttcgtc aattggaagt tcaataccta actctttttt tattatttgt aaagcccttt
     3901 tcccaagttc aaattcttct ttataatatt tcgatatttc ccagcgtagg ggattcgaaa
     3961 taataatccc ttctttataa cgttctatgc tcgaagaaat atgatccgtt aaattaatat
     4021 agataatttc atcaaaatta ttacccaatg ttattttacc taggttaatt attttttcgg
     4081 tgatgtacac caactccaaa ggaacgttaa taaacatctc tgtaaaacgg gtcatattat
     4141 ctctattttt gagaaaaaaa cttttctcaa tatcaattgg atttacttta tctccagttt
     4201 ttcttccaaa agctatgccc cttccaaaaa gaagaatatc gatatctttt ttactttgcg
     4261 caattacggc attgtggttt agtattcgtt ttatgatcat aaaatttccc ttttaaaata
     4321 aaaggaacct acttaaaaac atcaagaaac ttcttccgat gtgattaaat aggttcctgc
     4381 tcacttgtat tagtgataac atccttttat ttcaattttt aatggtgaca tgaagcttaa
     4441 ataattaata actctgtaac cattttcatt ttatgatatt tcaatctatt tgtcaagtac
     4501 ttgtagaaat ttttttattt tgtgtgattc gaatgtgata atggcaacag tctcactaaa
     4561 gaaatgaaaa tcatacatag aaatttttaa aaattttctc tatcgtaaac ctgccactag
     4621 ttcagaagct atactagctg attccaaacg taatatggtc atctcatcta ccttccctaa
     4681 taatggcatt gcaccatacc aaacaatagt cttattcacc aaaagaatag gcgttactat
     4741 ttttgattga gtaaaagaca ctttaatttt ctggctcttc aactgtgaac tacaccccaa
     4801 aagttagaca gaaaaaatct aacttttggg gtgttttatt atgaaa
//
LOCUS       DAVLIK010000090         4322 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLIK010000090 DAVLIK010000000
VERSION     DAVLIK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.090"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..792)
                     /locus_tag="VXE87_002047"
     CDS             complement(<1..792)
                     /locus_tag="VXE87_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843522.1"
                     /translation="MKEFYKKRFALTDRGARNLSKATLASFFVYCINMPPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVKGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNL"
     gene            complement(776..2530)
                     /locus_tag="VXE87_002048"
     CDS             complement(776..2530)
                     /locus_tag="VXE87_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843523.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     TLLALTIIGGLILGAMMGEQEFMKIYQEALSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            2690..3682
                     /locus_tag="VXE87_002049"
     CDS             2690..3682
                     /locus_tag="VXE87_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0843524.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIREEVVQNSTYSMADYVSIYTSYIVSANGEKFSPYQTLTANSL
                     CTFDFDNIRDDFLFLLHENSYYLCVSIGFKRELLEKHLSSININPESFYGALLQTNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELSIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT         1477 a          702 c          625 g         1518 t
ORIGIN      
        1 tagatttacg ccgacaaata tcacaacagc aagagatata aagctaaata ttgaagatat
       61 agacaaagtt aaaattgtag ttacttccgc ctttaagtgt actctctcac tatcttccat
      121 ttttttatat aagtcatctt taatatcctt cgataaatta tatgctttaa tctccatttg
      181 catttcgata ttttcttgaa agctttctga gttttttctt aagacatcat aatatctatt
      241 ctgtccctta acctgatatt ttttagataa aggtataaat ataaagctta aaatagatgg
      301 aataattaca gctaaaccca tcttgacatt gcccgctagc atcattacag atattaatgg
      361 gaaaaacagt accatgccgc ccacctttgg tattgagtgg ctcattgcat gctctatgcc
      421 ttcaatatca gccatgattg tttgtgaaat gtcggaaatg tcatgtttag aaaagtaaga
      481 tagaggtaat tttgataaat tctccgctgt ccttattctt aaatctgcac tttcttgata
      541 ggttgtgtta tataatttat cgtattcgat agaaagcaaa atatacattg ctatcaaagt
      601 caaaactgag aatactatat aaaagccatt gcttttgccc atattttcca aaacttcctg
      661 agcaaaaatc ataagtaata tggcaggagg catgtttata caataaacga aaaatgaagc
      721 cagtgttgct ttacttaaat ttcttgctcc tctatctgta agagcaaatc tttttttata
      781 aaactctttc atttgaaacc ctccattcat tcgcactgtt aaacatctct tgcaggctct
      841 tataccttgt atcttttgac attaattctt tgtcagaccc tctttctata atttttccac
      901 tatccataac aataatttca tcaaggtctt taattgtaga tagcctgtgt gcaatcatga
      961 taactgtttt atccttcata agatttttga aagctttttg caactcaaac tcgttatctg
     1021 ggtcaataga tgctgatgct tcatccataa taataatttt ggaatccttt aaaattgctc
     1081 tagcaattgc aattctttgt ttttctccac cggataaata aacacctttt gaccctatga
     1141 ttgtattttc tctttctggg aatttgtcta atattaaatc gcatcctgct aattttaagg
     1201 ctctcataac gtcatctttc gtcgcatctt tattagctaa agctacatta tcataaatgc
     1261 tcttcttgaa taattttgaa tcttgaaaaa caaaggaaat ggctttaatt aaggcttcgt
     1321 cagaatattc acttattgct atcccgccta tctttatgct tcctttatta acattgtaaa
     1381 aacctgatat aagttttgct actgttgatt tgcctgatcc agatgaaccg acaagtgcgt
     1441 aggactttcc ttcttctaaa ttaaaggata aattttcaat gacagcttta tcattataag
     1501 caaagctaac attctcaaat tctatattat agtttttaaa attattgaca ttaccatgca
     1561 ctaatttgtc tttttgcata tcttcgtaaa gcgcctctaa agtatctact gcataatttc
     1621 cttgagaaat atacatggag taccacatca ttctcatgaa tgaaacaaag agaactcctg
     1681 ataaaaataa aatcatgata agctcaagta aaatcacctt tgcgctagct aagctagtca
     1741 taaaataaac tataggaata attaaaattg caatcagtcc aaaaaataac cattgataca
     1801 aaacataagg ccttttacaa gatagggaat aatcataagc atactttgag taatctttta
     1861 tcgccttata aaagctttta aaagactcta catttgcttt aaatattttt acaacctgca
     1921 ttcctctaac gtactcgaca gtctcagcac ttagtttaga tagagcttct tggtatatct
     1981 tcataaattc ttgctcgccc atcatcgccc ctaaaattaa gccgccaatt atagtaagag
     2041 caagcaaagt tataccaacc cttatactta ctataaagcc tagtacaagg acaagtatag
     2101 gtgtgactat tgcctgagag ctatctggaa tcatgtgagc taccacctga tgagtttgtg
     2161 ctgcattatc atctatgatc tttcttattt gaccagatgg atttaagtca aagaacctaa
     2221 aacttgcttt ttccagacca tcgattcccc tttttcttaa atttgtttca agcctaaatc
     2281 ccaagatatg tgaaaacatt cctgagacaa aataaaatat cgctccactt gttagtgtaa
     2341 taacagattt taatgctata ctctctgcac cggataagtt tgaattaatt attaacttat
     2401 ctagaaattt gtagattaaa taatatccat atactgtaag tgcagcagat atagcagaaa
     2461 aaattatggc caaaacccca agatatttct tatcttggac ataagcaaat agttttttgt
     2521 aaatcttcat aagcatatct cctttcttta atatcccttt tagatataaa ttcgcttaat
     2581 tgataatatc tatcattgct tttctattat acatctgtta taattactaa tacaatagtt
     2641 ttgaattaat aaggctaatt ggaatattgt ctaaaaggga tagtgtgtta tgtcatatta
     2701 tgattttgta aaagattata tgaaagtaga tgaatgtaaa aacaatgaga agtattcaag
     2761 tgcaggtcat acattttgtt ggaaaaaaga gaattcaact tatgcagaag gcctatattg
     2821 gttttatgaa ggaggcagct tcattatcga tatacatgat ttttatatca gagaagaagt
     2881 agttcaaaac agtacctata gtatggcaga ttatgtttca atatacacaa gctacatagt
     2941 cagcgcaaat ggagaaaagt ttagtcctta tcaaacactt actgcaaact cattatgtac
     3001 ttttgacttt gacaatataa gagatgactt cctattttta ttacacgaga attcatatta
     3061 tctttgtgtt tctattggat ttaaaagaga acttttggaa aaacatctat catctattaa
     3121 cattaatcca gaatcatttt atggggcttt acttcaaact aatcaaatta tacttacaaa
     3181 ggccttagaa agagtggcaa tggaaatatt aaattgtaag atggacgctc ctgccgctga
     3241 ttttttcttt aaagcaaagg caaatgaatg gataagtata gtaattgaca catacttaaa
     3301 tagaaaaaaa tataaaattg aaattgatga tgataaagca cttgaagatg tagcaagatt
     3361 cttagatgat cattttgcaa cgaatgtaaa tcaaggcacg cttgaaaaaa tatctaaaat
     3421 gagtggtact aaattaaaaa atttatttaa ggaaaaatat tgtcaaagca ttacagagta
     3481 cactcaaaga aaaagaatga atgtagctga aactcttctt ttaaacactg aactatctat
     3541 aaaagagata gcagaatctg ttggatattc atctgccagc aaattttcta tctattataa
     3601 aagatacaag ggaaaacttc caagtgaagt ccgtaattta gcttgcaaac atcacaattt
     3661 taaatgcgat tattgtgatt aaagtaattt tttacaagcc atgtttttat atgaatttaa
     3721 gtgtatatgt gcatatatag tctgaataaa tttgatttga aaaatggata aaaaaataaa
     3781 ggcagtccga agaccgccaa tatttatctc tctgcacctt tactatggtc tttcttattt
     3841 gacttagatt tgtcatctgt cttaaagctt tttatttgcc ctaatatgga ctttttatcc
     3901 ttgtcttgac tctttacttg ttcttttgct tttaagagct tagaagacaa aaagagatat
     3961 tatattaaaa caatatttct ccggtactgg gactgggacg ggactaaaaa tctgaaaacg
     4021 tcctataatt aggtggattt agtgatatta taaaaaatag aatctagtat tttgaatggt
     4081 tttggatata ttgtacgttt ggaaaagaag aatgggagta attttaaact aacaaaaaat
     4141 gctttgaaat cagtgtttca gagcattttt gttctttctg taaataattt gcaaactata
     4201 gtaactgttg acttttactt aaccattttt cgattgtaag ttcaaaatgg tcaactacta
     4261 ttatattttc agggatcgta tcaaaatcaa ataataaatt atctgaatga gtttttataa
     4321 ct
//
LOCUS       DAVLIK010000091         4053 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLIK010000091 DAVLIK010000000
VERSION     DAVLIK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.091"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(112..387)
                     /locus_tag="VXE87_002050"
     CDS             complement(112..387)
                     /locus_tag="VXE87_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0843525.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VXE87_002051"
     CDS             complement(494..1333)
                     /locus_tag="VXE87_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0843526.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VXE87_002052"
     CDS             1475..2323
                     /locus_tag="VXE87_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0843527.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VXE87_002053"
     CDS             complement(2416..3333)
                     /locus_tag="VXE87_002053"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0843528.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVEQLKADEEVTRNWS"
     gene            3771..3976
                     /locus_tag="VXE87_002054"
                     /pseudo
     CDS             3771..3976
                     /locus_tag="VXE87_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT         1259 a          817 c          652 g         1325 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgca cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacagggg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat
     1681 ttttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggcgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg tagtgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgttc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattgt acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatctgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgct tatgtatgaa aaagcaatgc aactaactcc tgagaacttt aaattactaa
     3601 ttggtgccga aaaggtagaa tttagaatcg aggtacacct atggctgtaa aatttacaaa
     3661 atgagacaac ttgggcaaga tgtttgaaga atttcctaaa ctccctgatt tgaagcaagt
     3721 cactttccct gatgacaaag aaaaaagcca aaacagcaaa gaaaaactag atgactgctt
     3781 tccaacaact cccatctagt gtgcttcaga ctaggctatt tttctctcca tctgttagct
     3841 tggattctca gaccgtttca gctaaagaat atcttttccc ttatcagaag gaacggctca
     3901 aaccattcag acaagtgaag ggacgacaag ccaatatttg aaaccagata gcagttctta
     3961 tagtcaattg aaataaaatc tgaagaaatc gagtaggaaa ctcatatcaa tttttaacag
     4021 tgttctattc cagattcata ctcaatgaaa att
//
LOCUS       DAVLIK010000092         3868 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLIK010000092 DAVLIK010000000
VERSION     DAVLIK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.092"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..2717
                     /locus_tag="VXE87_002055"
     rRNA            <1..2717
                     /locus_tag="VXE87_002055"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            2794..2909
                     /gene="rrf"
                     /locus_tag="VXE87_002056"
     rRNA            2794..2909
                     /gene="rrf"
                     /locus_tag="VXE87_002056"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            2914..2986
                     /locus_tag="VXE87_002057"
     tRNA            2914..2986
                     /locus_tag="VXE87_002057"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2947..2949,aa:Val,seq:tac)
     gene            2989..3061
                     /locus_tag="VXE87_002058"
     tRNA            2989..3061
                     /locus_tag="VXE87_002058"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3022..3024,aa:Asp,seq:gtc)
     gene            3086..3158
                     /locus_tag="VXE87_002059"
     tRNA            3086..3158
                     /locus_tag="VXE87_002059"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3119..3121,aa:Lys,seq:ttt)
     gene            3164..3245
                     /locus_tag="VXE87_002060"
     tRNA            3164..3245
                     /locus_tag="VXE87_002060"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3198..3200,aa:Leu,seq:tag)
     gene            3264..3336
                     /locus_tag="VXE87_002061"
     tRNA            3264..3336
                     /locus_tag="VXE87_002061"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3297..3299,aa:Thr,seq:tgt)
     gene            3359..3430
                     /locus_tag="VXE87_002062"
     tRNA            3359..3430
                     /locus_tag="VXE87_002062"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3391..3393,aa:Gly,seq:gcc)
     gene            3438..3523
                     /locus_tag="VXE87_002063"
     tRNA            3438..3523
                     /locus_tag="VXE87_002063"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3472..3474,aa:Leu,seq:taa)
     gene            3533..3606
                     /locus_tag="VXE87_002064"
     tRNA            3533..3606
                     /locus_tag="VXE87_002064"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3567..3569,aa:Arg,seq:acg)
     gene            3622..3695
                     /locus_tag="VXE87_002065"
     tRNA            3622..3695
                     /locus_tag="VXE87_002065"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3656..3658,aa:Pro,seq:tgg)
     gene            3701..3774
                     /locus_tag="VXE87_002066"
     tRNA            3701..3774
                     /locus_tag="VXE87_002066"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3735..3737,aa:Met,seq:cat)
     gene            3788..3861
                     /locus_tag="VXE87_002067"
     tRNA            3788..3861
                     /locus_tag="VXE87_002067"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3822..3824,aa:Ile,seq:cat)
BASE COUNT         1038 a          803 c         1132 g          895 t
ORIGIN      
        1 aactgaaaca tctaagtagc tgcaggaaga gaaagcaaaa gcgattgcct tagtagcggc
       61 gagcgaaacg gcaggagggc aaaccgaaga gtttactctt cggggttgta ggactgcaat
      121 gtggactcaa agattataga agaatgattt gggaagatca gccaaagaga gtaatagcct
      181 cgtatttaaa atagtctttg tacttagcag tatcctgagt acggcgggac acgtgaaatc
      241 ccgtcggaat ctgggaggac catctcccaa ccctaaatac tccctagtga ccgatagtga
      301 accagtaccg tgagggaaag gtgaaaagca ccccgggagg ggagtgaaat agaacctgaa
      361 accgtgtgcc tacaacaagt tcgagcccgt taatgggtga gagcgtgcct tttgtagaat
      421 gaaccggcga gttacgttat gatgcgaggt taagttgaag agacggagcc gtagggaaac
      481 cgagtctgaa tagggcgcct tagtatcatg acgtagaccc gaaaccatgt gacctaccca
      541 tgagcaggtt gaaggtgcgg taagacgcac tggaggaccg aaccagggca cgttgaaaag
      601 tgcttggatg acttgtgggt agcggagaaa ttccaaacga acttggagat agctggttct
      661 ctccgaaata gctttagggc tagcgtcgac attagagatt cttggaggta gagcactgtt
      721 tgggtgaggg gtccatcccg gattaccaat ctcagataaa ctccgaatgc caatgaatta
      781 tggtcggcag tcagactgcg agtgctaaga tccgtagtcg aaagggaaac agcccagacc
      841 accagctaag gtcccaaaat aattgttaag tggaaaagga tgtggggttg cacagacaac
      901 taggatgtta gcttagaagc agctattcat tcaaagagtg cgtaatagct cactagtcga
      961 gtgaccctgc gccgaaaatg taccggggct aaaacaattt accgaagctg tggatacctt
     1021 tataggtatg gtaggagagc gttctatgtg tgatgaaggt ataccgtgag gagtgctgga
     1081 acgcatagaa gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc
     1141 gtaagactaa ggtttccagg ggaaggctcg tccgccctgg gttagtcggg acctaaggag
     1201 agaccgaaag gtgtatccga tggacaacag gttgatattc ctgtactaga gtatgtagtg
     1261 atggagggac gcagtaggct aactaaagca gacgattgga agagtctgtc taagcagtga
     1321 ggtgtgaatt gagtcaaatg cttaattcta taacattgag ctgtgatggg gagcgaagtt
     1381 tagtagcgaa gttagtgacg tcacactgcc aagaaaagct tctagcgttt aaacatactc
     1441 tacccgtacc gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg agcgagagaa
     1501 ctctcgttaa ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg tgctgacttt
     1561 aagtcagccg cagtgaatag gcccaagcaa ctgtttatca aaaacacagc tctctgctaa
     1621 atcgtaagat gatgtatagg gggtgacgcc tgcccggtgc tggaaggtta agaggagtgc
     1681 ttagcgtaag cgaaggtatg aattgaagcc ccagtaaacg gcggccgtaa ctataacggt
     1741 cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg cgtaatgatt
     1801 tgggcactgt ctcaacgaga gactcggtga aattttagta cctgtgaaga tgcaggttac
     1861 ccgcgacagg acggaaagac cccatggagc tttactgcag tttgatattg agtgtctgta
     1921 ccacatgtac aggataggta ggagtctaag agatcgggac gccagtttcg aaggagacgc
     1981 tgttgggata ctacccttgt gttatggcca ctctaaccca gataggtgat ccctatcgga
     2041 gacagtgtct gacgggcagt ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc
     2101 ccaaaggttc cctcagaatg gttggaaatc attcgcagag tgtaaaggta taagggagct
     2161 tgactgcgag agctacaact cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc
     2221 cgtatggaag ggccatcgct caacggataa aagctaccct ggggataaca ggcttatctc
     2281 ccccaagagt tcacatcgac ggggaggttt ggcacctcga tgtcggctcg tcgcatcctg
     2341 gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggcac gcgagctggg
     2401 ttcagaacgt cgtgagacag ttcggtccct atccgtcgcg ggcgtaggaa atttgagagg
     2461 atctgctcct agtacgagag gaccagagtg gacttaccgc tggtgtacca gttgtcttgc
     2521 caaaggcatc gctgggtagc tatgtaggga agggataaac gctgaaagca tctaagtgtg
     2581 aaacccacct caagatgaga tttcccatga ttatatatca gtaagagccc tgagagatga
     2641 tcaggtagat aggttagaag tggaagtgtg gcgacacatg tagcggacta atactaatag
     2701 ctcgaggact tatccaaagt aactgagaat atgaaagcga acggttttct tgatttgaat
     2761 agatattcaa ttttgagtag gtattactca gagttaagtg acgatagcct aggagataca
     2821 cctgtaccca tgccgaacac agaagttaag ccctagaacg ccggaagtag ttgggggttg
     2881 ccccctgtga gatagggaag tcgcttagct ttagggagtt tagctcagct gggagagcat
     2941 ctgccttaca agcagagggt cagcggttcg atcccgttaa ctcccaaagg tcccgtagtg
     3001 tagcggttat cacgtcgccc tgtcacggcg aagatcgcgg gttcgattcc cgtcgggacc
     3061 gtttaaggta acgcaagtta ttttagactc gttagctcag ttggtagagc aattgacttt
     3121 taatcaatgg gtcactggtt cgagcccagt acgggtcata tatgcgggtt tggcggaatt
     3181 ggcagacgca ccagatttag gatctggcgc ttaacggcgt gggggttcaa gtcccttaac
     3241 ccgcattaag atataacaaa tgagccggct tagctcagtt ggtagagcat ctgatttgta
     3301 atcagagggt cgcgtgttca agtcatgtag ccggcatttt tagatagaag aaaacagtgc
     3361 gaacgtagtt cagtggtaga acaccacctt gccaaggtgg gggtcgcggg ttcgaatccc
     3421 gtcgttcgct tagagaggcc ggggtggcgg aactggcaga cgcacaggac ttaaaatcct
     3481 gcgattggta acgatcgtac cggttcgatt ccggtcctcg gcataatatg gagcaccctt
     3541 agctcaactg gatagagtac ctgactacga atcaggcggt tagaggttcg actcctctag
     3601 ggtgcatttt tctatttaac tcgggaagta gctcagcttg gtagagtact tggtttggga
     3661 ccaaggtgtc gcaggttcga atcctgtctt cccgattcat ggcggtgtag ctcagctggc
     3721 tagagcgtcc ggttcatacc cgggaggtcg ggggttcgat ccccttcgcc gctataatga
     3781 tcttgtcgga cctttagctc agctggttag agctctcggc tcataaccga gtggtcgtag
     3841 gttcaagtcc tacaaggtcc atttgaat
//
LOCUS       DAVLIK010000093         3771 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLIK010000093 DAVLIK010000000
VERSION     DAVLIK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3771
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.093"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            158..385
                     /locus_tag="VXE87_002068"
     CDS             158..385
                     /locus_tag="VXE87_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843529.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            673..3570
                     /gene="nanA"
                     /locus_tag="VXE87_002069"
     CDS             673..3570
                     /gene="nanA"
                     /locus_tag="VXE87_002069"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0843530.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSS
                     DTKEDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGNPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1295 a          634 c          848 g          994 t
ORIGIN      
        1 gttttaaaaa taaggtataa taaatttact aacacttata aaaagtgata gaatctatct
       61 ttatgtatat ttaaagatag attgctgtaa aaatagtagt agctatgcga aataacagat
      121 agagagaagg gattgaagct tagaaaaggg gaataatatg atatttaagg cattcaagac
      181 aaaaaagcag agaaaaagac aagttgaact acttttgaca gtttttttcg acagttttct
      241 gattgattta tttcttcact tatttgggat tgtccccttt aagctggata agattctgat
      301 tgtgagcttg attatatttc ccattatttc tacaagtatt tatgcttatg aaaagctatt
      361 tgaaaaagtg ttcgataagg attgagcagg aagtatggtg taaatagcat aggctgatgt
      421 ccatcatttg cttataaaga gatattttag tttaattgca gcggtgccct ggtagataaa
      481 ctagattggc aggagtctga ttggagaaag gagaggggaa aattggcacc aatttgagat
      541 agtttgttta gttcattttt gtcatttaaa tgaactgtag taaaagaaag ttaataaaag
      601 acaaactaag tgcattttct ggagtaaatg tcttatttca gaaatcggga tatagatata
      661 gagaggatca gtatgaatcg gagtgttcaa gaacgtaagt gtcgttatag cattaggaaa
      721 ctatcggtag gagcggtttc tatgattgta ggagcagtgg tatttggaac gtctcctgtt
      781 ttagctcaag aaggggcaag tgagcaacct ctggcaaatg aaactcaact ttcgggggag
      841 agctcaaccc taactgatac agaaaagagc cagccttctt cagagactga actttctggc
      901 aataagcaag aacaagaaag gaaagataag caagaagaaa aaattccaag agattactat
      961 gcacgagatt tggaaaatgt cgaaacagtg atagaaaaag aagatgttga aaccaatgct
     1021 tcaaatggtc agagagttga tttatcaagt gaactagata aactaaagaa acttgaaaac
     1081 gcaacagttc acatggagtt taagccagat gcatcagctc cacgctttta caatctcttc
     1141 tctgtatcca gtgacaccaa ggaagatgag tacttcacta tggcagttta caataatact
     1201 gctactctag aggggcgtgg ttcggatggg aaacagtttt acaataatta caacgatgca
     1261 cccttaaaag ttaaaccagg tcagtggaat tctgtgactt tcacagttga aaaaccgaca
     1321 gcagaactac ctaaaggccg agtgcgcctc tacgtaaacg gggtattatc tcgaacaagt
     1381 ctgagatctg gcaatttcat taaagatatg ccagatgtaa cgcatgtgca aatcggagca
     1441 accaagcgtg ccaacaatac ggtttggggg tcaaatctac agattcggaa tctcactgtg
     1501 tataatcgtg ctttaacacc agaagaggta caaaaacgta gtcaactttt taaacgctca
     1561 gatttagaaa aaaaactacc tgaaggagcg gctttaacag agaaaacgga catattcgaa
     1621 agcgggcgta acggtaaccc aaataaagat ggaatcaaga gttatcgtat tccagcactt
     1681 ctcaagacag ataaaggaac tttgatcgca ggtgcagatg aacgccgtct ccattcgagt
     1741 gactggggtg atatcggtat ggtcatcaga cgtagtgaag ataatggtaa aacttggggt
     1801 gaccgagtaa ccattaccaa cttacgtgac aatccaaaag cttctgaccc atcgatcggt
     1861 tcaccagtga atatcgatat ggtgttggtt caagatcctg aaaccaaacg aatcttttct
     1921 atctatgaca tgttcccaga agggaaggga atctttggaa tgtcttcaca aaaagaagaa
     1981 gcctacaaaa aaatcgatgg aaaaacctat caaatcctct atcgtgaagg agaaaaggga
     2041 gcttatacca ttcgagaaaa tggtactgtc tatacaccag atggtaaggc gacagactat
     2101 cgcgttgttg tagatcctgt taaaccagcc tatagcgaca agggtgatct atacaagggt
     2161 gaccaattac taggcaatat ctacttcaca acaaacaaaa cttctccatt tagaattgcc
     2221 aaggatagct atctatggat gtcctacagt gatgacgacg ggaagacatg gtcagcgcct
     2281 caagatatta ctccgatggt caaagccgat tggatgaaat tcttgggtgt aggtcctgga
     2341 acaggaattg tacttcggaa tgggcctcac aagggacgga ttttgatacc ggtttatacg
     2401 actaataatg tatctcactt aaatggctcg caatcttctc gtgtcatcta ttcagatgat
     2461 catggaaaaa cttggcatgc tggagaagcg gtcaacgata accgtcaggt agacggtcaa
     2521 aagatccact cttctacgat gaacaataaa cgtgcgcaaa atacagaatc aacggtggta
     2581 caactaaaca atggagatgt taaactcttt atgcgtggtt tgactggaga tcttcaggtt
     2641 gctacaagta aagacggagg agtgacttgg gagaaggata tcaaacgtta tccacaggtt
     2701 aaagatgtct atgttcaaat gtctgctatc catacgatgc acgaaggaaa agaatacatc
     2761 atcctcagta atgcaggtgg accgaaacgt gaaaatggga tggtccactt agcacgtgtc
     2821 gaagaaaatg gtgagttgac ttggctcaaa cacaatccaa ttcaaaaagg agagtttgcc
     2881 tataattcgc tccaagaatt aggaaatggg gagtatggca tcttgtatga acatactgaa
     2941 aaaggacaaa atgcctatac cctatcattt agaaaattta attgggaatt tttgagcaaa
     3001 gatctgattt ctcctaccga agcgaaagtg aagcgaacta gagagatggg caaaggagag
     3061 atgggcaaag gagttattgg cttggagttt gactcagaag tattggtcaa caaggctcca
     3121 acccttcaat tggcaaatgg taaaacagcg actttcctaa cccagtatga tagcaaaacc
     3181 ttgttgtttg cagtagataa ggaagatatc ggacaggaaa ttattggtat agctaaagga
     3241 agcatcgaaa gtatgcataa tcttcctgta aatctagcag gtgccagagt tcctggcgga
     3301 gtaaatggta gcaaagcagc ggtgcatgaa gttccagaat ttacaggggg agttaatggt
     3361 acagagccag ctgttcatga aatcgcagag tataagggat ctgattcgct tgtaactctt
     3421 actacaaaag aagattatac ttacaaagct cctcttgctc agcaggcact tcctgaaaca
     3481 ggaaacaagg agagtgacct cctagcttca ctaggactaa cagctttctt ccttggtctg
     3541 tttacgctag ggaaaaagag agaacaataa gagaagaatt ctaaacattt gattttgtaa
     3601 aaatagaagg agatagcagg ttttcaagcc tgctatcttt ttttgatgac attcaagctg
     3661 atacgaaatc ataagaggtc tgaaactact ttcagagtag tctgttctat aaaatatagt
     3721 agattgaaat aagatgtgaa caactctatc aggaaagtca aattaattta t
//
LOCUS       DAVLIK010000094         3716 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLIK010000094 DAVLIK010000000
VERSION     DAVLIK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.094"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            18..191
                     /locus_tag="VXE87_002070"
     CDS             18..191
                     /locus_tag="VXE87_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843531.1"
                     /translation="MDKAKIGITNVEFSGTGGIESATVKLELNIYGADTFSAIELLPK
                     ILTDIHSLSYEVD"
     gene            458..982
                     /locus_tag="VXE87_002071"
     CDS             458..982
                     /locus_tag="VXE87_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0843532.1"
                     /translation="MSEEINATVSIESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            1005..2030
                     /locus_tag="VXE87_002072"
     CDS             1005..2030
                     /locus_tag="VXE87_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEV0843533.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFSAALGNVSDNVTMGKEAGANNAYNAILDVSEKLDEL
                     GITKERLLFVTPKFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKKSAQGKTVNRAKAWKTGTAYKEGDTVTHEDKVYVAIKDITSSTNAPGSDSANW
                     KEKTGKK"
     gene            2040..2228
                     /locus_tag="VXE87_002073"
     CDS             2040..2228
                     /locus_tag="VXE87_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843534.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
     gene            2230..2541
                     /locus_tag="VXE87_002074"
     CDS             2230..2541
                     /locus_tag="VXE87_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0843535.1"
                     /translation="MSIELLKKLTGEEDTQLLMLFQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            2522..2860
                     /locus_tag="VXE87_002075"
     CDS             2522..2860
                     /locus_tag="VXE87_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843536.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            2835..3350
                     /locus_tag="VXE87_002076"
     CDS             2835..3350
                     /locus_tag="VXE87_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0843537.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELIISIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            3347..3715
                     /locus_tag="VXE87_002077"
     CDS             3347..3715
                     /locus_tag="VXE87_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843538.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
BASE COUNT         1241 a          655 c          861 g          959 t
ORIGIN      
        1 cccagaaagg attgaaaatg gataaagcaa aaattgggat aactaacgta gaattttcag
       61 gaacaggcgg aattgaatca gcgacagtga aattagagtt aaatatttat ggggcggata
      121 cgttcagcgc gattgagtta ctacctaaaa tattaaccga cattcattca ttatcgtatg
      181 aagttgattg attgtgacat taaaaggagt aagatatgtt tatatgggat tgggtatcaa
      241 tcgctttcgg gtggttggta tttttgtttt tgatgctgat tatcatagca tttgtaaaaa
      301 aagtgattga agaaaataca aaataatcta accgtatgga atcccgtacg gtttttatat
      361 tgtccaaact gtgccgatga cattaaaagc tgcactgttc cgtcgccgga cgtaaagcga
      421 gattatcgag tggcgacgta atcgctggag gacaattatg tcagaagaaa tcaatgcaac
      481 tgtatctatt gaatcaactg agactgtcga cactcaagga aatgttgatt cagtgcagga
      541 agaaaagcac gaacgaactt tcactcgtgc tgaaatcggt aagatgctat ctgccgagcg
      601 ctctaaatgg gaagctgagc aagaagccaa ggaaaacgaa gctaagaagc ttgctaagat
      661 gaacgctgat gaaaaacaga aatatcagtt ggatcagcgt gagcaagaac tagctgaccg
      721 tgaaaaggct attgctcgta aggaattgac cgcagaggct aaagcaatgc taagtgaacg
      781 tgacttacct gttgagttag taaatgtagt cgatttgaca aacgcagaga cggtatctga
      841 atctatcacc tctatccaaa aagcatggga agagtcagtt cagaagggag tctctgaacg
      901 tatgaaaggt agtgcaccta tcaaaaatgc acaaacagtc cagcaagaag tcacggaaaa
      961 atggcgtaaa gacttcttgt aataaaagaa aagaggaaaa ataaatggca tttgaagaat
     1021 taaacacagc agaatcacgc aagaaacatc ttgggattat tgaggatgta cttgcagtaa
     1081 attcatattc aacaccactt gtgacatcaa gcgatgcagt aaccttgcaa ggtcgctctt
     1141 ttacagtagc aactggtaac acaacagagt tgaaagacta caaacgtaac aaagacaacg
     1201 aatttgatca cgttgaagtt gaagaaaagg tttataccct tgatgaagaa aaatactggg
     1261 gtcgtttcgt agatcaattg gacgaacgtg actctaatgg tcaagtgaat atcaattatg
     1321 ttattgcccg tcaagcggca gaagtagtag ctccatatct tgatgaacta cgttttagtg
     1381 cagcgcttgg taatgttagc gacaacgtta ctatgggcaa agaagcagga gcgaacaacg
     1441 catacaacgc aattcttgat gtttctgaga aacttgatga gcttggaatt acaaaagagc
     1501 gcttgctttt tgtaacacct aaattctaca aagcgatcaa gtctgaaatc gttcgtctac
     1561 cacatggtga cgcagataag aaagtccttg gaaaaggata tgttggtgaa ttggatgatt
     1621 acacagtcta taaagttcct tctaaattct tgaaaggtgt taatgccctt gctactgctc
     1681 caggtgttgt tacatctcca gtacaagtag acaatactaa gtacaacgat aacattccag
     1741 gtcgatttgg tgaattggta gagcaattac tttacactgg tgcatttgtg cttgaacact
     1801 tcaaaaaata catcatcaca attgcagatt ctaagcctgc tgctaaaaaa tcagcccaag
     1861 gcaagacagt gaaccgtgct aaagcgtgga agactggaac agcctataaa gaaggtgata
     1921 cagtaacgca tgaagataaa gtctatgttg ctatcaaaga catcactagc tcaaccaatg
     1981 caccaggctc tgactcagct aactggaaag aaaaaactgg taagaaatag gtcttagtta
     2041 tgaaatttaa aatcaaacaa gatttctatg attgggaatc aaatgtgaaa cgactggcag
     2101 gagaggaact tgagattact gaggagcgct atgctgagct ggctgacaat attgccagca
     2161 acggtgtcgc tatctcagat gttcttgaga aaatcctccc tgaacctgag ttcttagaag
     2221 aggattgata tgtctataga gttgctgaag aaattaacag gcgaagaaga tactcagctt
     2281 ctcatgttgt tccaaacaag ggctacaaat cttatcttgt cagagactaa tcgcacatct
     2341 ttgacacctg ctttaagtct tttaatacct gaggttgcta tcgagctcca caaccgctca
     2401 ggagcggaag gagagcgttc tagaaccgaa ggtggtatag cagtagtcta cggagaaaat
     2461 ggcctgtcta cgggtcttct acagcgaata cgcatgcaca ggctagcaag ggtggcaggt
     2521 catgtttttg aagcagagta gactgaaacc ttatccaatg cgacggtttg aaaagactgt
     2581 cactgaggaa ggtgtcgcga aagaagggta tgccaaggaa gctgagacag tccgccttga
     2641 attgtggcca gctagtagca agttacaatc tgaattgtat ggcgagcgtg tcaatgatat
     2701 tttgaacgca aatgccaaca agtcagctac tatcaaagtg aaagatggtg tgtgtatcga
     2761 tagccagaca gaagtgactc acagggttat ttctaaaaag gtctacacac atcatcaagt
     2821 tttggagtta gagcgtgtca gggctactag gggcagatag gcttatagct aaatgtagac
     2881 gattggctag taaaaaaact ggcgaggata tcgtcttacg tgcggtacac aatgctacta
     2941 taaaggttgt ccaagcagat gcaagaagac tcgcaccagc gagagatgga gagcttataa
     3001 ttagtatcaa aactagagca aaaatggacg gagataaggc tataggcgaa gtttacacca
     3061 accttaaata cgctccttac gttgagtttg gaacaggacc aataggacaa gctaaccatt
     3121 cgggtatctc tccagaggtc agcgtgactt acaagtctaa tccttggtat gtgcatgaag
     3181 accaaataaa tgtaggaccg taccactttc aaaagattgg ggagttctac aagatgtatg
     3241 gtcaacctgc ccagccttat ctttatccag ctttgagaga caatcaagag cgtgtgtcta
     3301 agaatatttc gaattatgtc cgtagaaaga taagagaaca aataaaatga ttaatatcaa
     3361 gcctgttatt tataaagaat tgcaaaaggt tgcagataat gtgaccgata cttatcctag
     3421 cgattgggag actttcccag tcgttatttt tttagaagaa caaaacaagc cgggtgattg
     3481 gtttgatgac caggaacaaa aatcatctat ccgctataag gtggatatct ttgatgatac
     3541 cagcactagt gagttagctg ttaaaatcaa tcagattttt gagtctttag gtttgcgaag
     3601 aactgactgc caagacgtgc cagacccgtc tcatttgaga cataaggtca tgcgttttga
     3661 aggtgtcgtt gatttagact cagagcttgt ttttcaattt agaatggaga attaaa
//
LOCUS       DAVLIK010000095         3640 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLIK010000095 DAVLIK010000000
VERSION     DAVLIK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3640
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.095"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(232..525)
                     /gene="rpmA"
                     /locus_tag="VXE87_002078"
     CDS             complement(232..525)
                     /gene="rpmA"
                     /locus_tag="VXE87_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0843539.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(542..886)
                     /locus_tag="VXE87_002079"
     CDS             complement(542..886)
                     /locus_tag="VXE87_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0843540.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(902..1216)
                     /gene="rplU"
                     /locus_tag="VXE87_002080"
     CDS             complement(902..1216)
                     /gene="rplU"
                     /locus_tag="VXE87_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0843541.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(1252..1339)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(1398..2033)
                     /locus_tag="VXE87_002081"
     CDS             complement(1398..2033)
                     /locus_tag="VXE87_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0843542.1"
                     /translation="MTFCAGYVDAYTFIVRGNILVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLSMLFASWQKKVKEKASF"
     gene            2504..2803
                     /locus_tag="VXE87_002082"
     CDS             2504..2803
                     /locus_tag="VXE87_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0843543.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            3022..3640
                     /locus_tag="VXE87_002083"
                     /pseudo
     CDS             3022..3640
                     /locus_tag="VXE87_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1188 a          742 c          626 g         1084 t
ORIGIN      
        1 aagtgcaaac taggaagtta gccgcaggct gtacttgagt acggcaaggt gaaactgacg
       61 tggtttgaat ttgattttcg aagagtatca atccactata catattaaaa gtatggatat
      121 caaaacaaaa aaacaggctc tccgaaaact cggaaagcct tattttaagc tgtttctagc
      181 ttcctcacct ttacatttca aggttcggga taaaaggttc aatggacctt tttatttagc
      241 gattgggtaa acagaaactt gttttttatc gcgtccttta cgttcaaagc gtactacgcc
      301 ttcaacttta gcgaacaaag tatcgtctcc accacgacca acgtttacac ctggatagat
      361 gtgtgtacca cgttgacggt aaaggattga tccacctgtt acagtttgtc cgtcagctgc
      421 tttagctcca agacgtttcg cttgtgaatc acgtccgttt gatgtagaac ctccaccttt
      481 tttgtgggcg aaaagttgca agttgttaag agtcattttt aacataatgt tttcctccgt
      541 gttagttttc tgtgataact ctggtttgga cgaactcaga agagttctcc gataagtttg
      601 ccatacctaa gaaaaatgat tcaaagaata actgggtcat ttctctctgg tgtgaaggaa
      661 gatcttttgg tatttcaacc atcagatagc caccttcatc ttcgtttaat tctaggattg
      721 gttcatagcc tgcaaatttc tcaatagaat tgataaagtt aatggcaagc gtagaaaccg
      781 atgcacacac gacatctaag ccgtattcgc cactctcggc gtgtccagta atttccgcac
      841 tcctcagctc gccatcttcg gctctctcaa agactgcctg tatcatgtgt tctccttaaa
      901 attaagcgtt gattgcgttg atgacaactt ttgtatatgg ttgacggtga ccttgtttac
      961 ggtggctacc ttttttaggt ttgtacttgt aagtaaccac tttcttttgt tttccttgtt
     1021 tttcaacagt tccaactaca gtagctccag caacaagtgg agttccgaca acagtgtttt
     1081 caccaccaac aagaacaact tcgttaaaag taacttcttg accagcttca acgttcaatt
     1141 tttcaacgta aactgcttga ccaacttcaa ctttaacttg ttttccgcca gttttgataa
     1201 ttgcgtatgt gctcattatg cacctcctat gatttttatg ggtttccccg attttttgtg
     1261 aagactcgcc tagcatcgtg ggacgaacca cttaaacttg aataatcaag caacgatgtt
     1321 cgtgcggttg cacaggatcg tgcatagtca actcttcaag tatagcatat ctcctatttt
     1381 cttacaagta ataacaccta aaatgaagct ttttctttta cttttttctg ccaagaggca
     1441 aaaagcatgc tgaggtaaaa aacgctcatc ataataggaa caccaagaat ggtcttttca
     1501 tgatagaaaa tcgtcaaata ggctgaaaag acaacgccaa ggacaaaact actaagcagg
     1561 ctaacaaata tgaatccttc acgcaaaaaa ggagtgtgct tggttcggaa ataatctcca
     1621 aaagccagca tggtccgttt gatattccct gtcataaaag cgttattata ggcaataccc
     1681 gacacttctc caaaagcagt tgtcaccagt cccatacaga aggccaaggg cggcactaga
     1741 tagatattat ctacagtttg tggcacaaaa ccaataatta ttgataggat tgctaaagga
     1801 atcaaggaca gaatagattt tttcacaatt ctcaattttt ccttataaat cgttaataaa
     1861 aagactccca tcataaacgc tattaaggtt aaaagcttat ccctaatatc cgaaacatta
     1921 ttttgtatga gctctaccga aagaaagaca acatttccag cttgtccagc tacaaggata
     1981 ttcccgcgaa caataaaagt gtaagcatcc acatatccag cacaaaacgt caaaaaagtg
     2041 ctaacctttt agactgacgt gatatttttc ttataggtaa taacctcatt ttccctccca
     2101 ttgtattttc tcttagaaat attgtaccat tttctttcta aaaaatcgta ggctaccatt
     2161 tagattttac tattagcata aaaataataa tagacaacta tttatccaaa aatagataga
     2221 ggtaacatgt ttgcaaacaa agcatacgaa cctttagtaa aatcatttcc atgaaactag
     2281 aatagagccc ctcttagcaa aaatcattat tttaatttat ttctaatcac tccttgacat
     2341 aaataactct caccaataaa agactatgtc ttaaaaaaat ggtataataa aatcaatact
     2401 tgggcttgat ggctatgcta ctaataacaa ttaggagaga aaatcaggca cttgttaaca
     2461 acaaggatta tccccttgag atgaaaggaa ctttagaaat cttatgatga acatgcaaaa
     2521 catgatgcgt caagcacaaa aacttcaaaa acaaatggaa caaagccaag ctgaacttgc
     2581 tgctatgcaa tttgttggca aatctgctca agatcttgtc caagcaacct taactggcga
     2641 taagaaagtt gtcagcattg atttcaatcc agctgtcgtt gacccagaag accttgagac
     2701 tctttctgat atgaccgttc aagccatcaa ctctgctctt gaacaaatcg atgaaactac
     2761 taagaaaaaa ctgggtgctt tcgctgggaa attgccattc taaaaacaag gagctagaac
     2821 aatgcttgtc gataacaaag gctaagaaag gtgcaaaaat tataaaaaac gcatagtatc
     2881 aagcaaccta aaactttggg ctctataata tttgtagtgg gtaaatcccc tatagatatt
     2941 atggagccta ttttgtgtag aaaaaaagtc ccatatgacc tataatgaaa agcgacaaaa
     3001 caactcatta gaaagaatca tatggaacaa ttacatttta tcacaaaatt actagacatt
     3061 aaagacccta atatccagat tttagacatc atcaataagg atacacacaa ggaaatcatc
     3121 gccaaactgg actatgaagc tccatcttgc cctgagtgcg gaagtcaaat gaagaaatat
     3181 gactttcaaa aaccttctaa aattccttat cttgaaacaa ctggtatgcc tactagaatt
     3241 ctccttagaa agcgtcgttt caagtgctat cattgttcta aaatgatggt tgctgaaact
     3301 tctatcgtca agaagaatca tcaaatccct cgtatcatca accaaaagat tgctcaaaag
     3361 ttaattgaaa agaattctat gaccgatatt gcccatcagc tggccatctc aacttcaact
     3421 gttattcgta agctcaatga ttttcacttt aaacatgatt tttcgcgtct tcctgagatt
     3481 atgtcttggg acgttgaaac agtccgggga gtgactgttt caatcgggag atggagatga
     3541 gcttcattgc gcaagatttt aacaatctca atatcatcac tgttcttgag ggaagaacac
     3601 aagctatcat tcgaaatcac tttcttcgct acgatagagc
//
LOCUS       DAVLIK010000096         3536 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLIK010000096 DAVLIK010000000
VERSION     DAVLIK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.096"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..885
                     /locus_tag="VXE87_002084"
     CDS             <1..885
                     /locus_tag="VXE87_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0843544.1"
                     /translation="LAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDY
                     SLKKFDIDLKDVEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYD
                     YDKGQILIDGKDIKEISTESLFNKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRA
                     AKLANCTDFIEKMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASL
                     DVNNEKKIQESLNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKS
                     KIYKNLIEKTKMAEEFIY"
     gene            896..1480
                     /locus_tag="VXE87_002085"
     CDS             896..1480
                     /locus_tag="VXE87_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0843545.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            1480..2175
                     /locus_tag="VXE87_002086"
     CDS             1480..2175
                     /locus_tag="VXE87_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0843546.1"
                     /translation="MPTFSSNAPFNPNPISKILVIFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            2163..3527
                     /locus_tag="VXE87_002087"
     CDS             2163..3527
                     /locus_tag="VXE87_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843547.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGKIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         1305 a          440 c          674 g         1117 t
ORIGIN      
        1 ctagctgcta tgaagataaa agactcttta gatgcatcta aagagggctt gatggaaata
       61 ttttatttat cgcccaaaat agaaagatta aaagaaattc aaaatcaaga tttacaagaa
      121 ggcgatgact atagtttaaa aaaatttgat attgatctaa aagatgttga gtttgcctac
      181 aataaagacg caaaagtttt aaatggtgta agttttaaag ctaagcaggg agaggtcact
      241 gctttggtag gtgcaagtgg ctgcggtaaa acaactatct tgaaacttat atcaagactt
      301 tatgattatg acaagggaca aatcttaatc gatggcaaag atataaaaga aatatcaaca
      361 gaatctcttt ttaataaggt ctctatagtt ttccaagatg tggttctctt taatcaaagc
      421 attatggaaa atattagaat cggaaagcaa gatgcaagtg acgaagaggt taaaagagca
      481 gcaaaacttg caaattgcac agattttata gaaaaaatgg ataaaggttt cgatacagtt
      541 attggtgaga acggagctga gctatcagga ggagaaagac aaagattatc aatagccaga
      601 gccttcttaa aagatgcgcc gatattgatc ttagatgaga taacagcaag ccttgatgtt
      661 aacaacgaga aaaagattca agagtcttta aataatttag ttaaagataa aactgttgta
      721 atcatttcac atagaatgaa atccatagaa aatgcagaca agatagtagt tcttcaaaac
      781 ggaagagtag aaagcgaagg taagcatgaa gagcttttac aaaaatcaaa aatttacaaa
      841 aatttaatag aaaagacaaa aatggcagaa gaatttattt attaggagga ctacaatgga
      901 taataaaaaa ttaaaagtaa aagatttagt aagcatcggt gtttttggcg taatttattt
      961 tgccttcatg tttggagttg gtatgatggg cttgattcca atattgttct taatataccc
     1021 gacagtatta gccatagttg caggaactgt tgttatgtta tttatggcta aggttcaaaa
     1081 gccatgggca ctatttatat ttggtatgat atcaccactt gtgatgtttg cagctggtca
     1141 tacctacgta gttgtggttt tatcacttat agtaatgata atagcagaat taattagaaa
     1201 gattggtaat tataattcat ttaaatacaa tatgctttct tatgcaatct tcagcacatg
     1261 gatatgtagc tctttaatgc aaatgctttt agcaaaagaa aaatatatgg agtggtcttt
     1321 gatgacgatg ggaaaagatt atgttgatgt attagaaaag ttaataactt atcctcatat
     1381 ggctttagta gccttaggtg ctttcttagg aggaattctt ggagcatata taggcaaggc
     1441 tctattgaaa aaacactttg aaaaagcagg cattgtataa tgcctacttt ttcttcaaat
     1501 gctcccttta atcccaatcc gatctctaag atattagtca tatttatcac aggcttaact
     1561 gttatgcata gcataaacat ccgttttgag ctggcaattg tttgtcttat tggtattttg
     1621 ctttatttga atggatacaa aaaaacactt ttcaaatgga ttatattgtg tgggatactt
     1681 tactccttgc ctaattttat ggtgctatct gaattaaacc ctatagttaa gatgtttttg
     1741 agtataccta ttgttattag aatgtttatt ttaccattta tggcagcaag ctttatgata
     1801 aagacctcgg atgtaggcgc aataatttca tcgatggata agcttaagat ttcaaagaat
     1861 gtatccatac ctattgcggt tatgtttaga ttcttcccat cttttaagga ggagaagaaa
     1921 aacatcaaaa tggctatgag agtaagaggg ataaatttta aaaacccagt caaatatctt
     1981 gaatatgttt ctgtgccact actcattata tcatctaata tatcagatga cattgcaaaa
     2041 gcggcagaaa caaaggcaat agaaaatcca attgccaaga ccagatacat tcgcgtaaag
     2101 atacagctaa ttgattttgt ttatgtttta gcggttgctg gacttattgt gggaggctta
     2161 atatggttga aataaaaaat ttaagtcttg attatggtga agagcatata ttagatgata
     2221 tatcactatc catagccgag ggagagtgcg tgctatttac aggaaaaagt ggaaatggta
     2281 agtcatcttt aataaattca atcaatggac tagctgtaag gtatgataac gcaaagacaa
     2341 agggcaaaat aattattgat ggtaagaata taaaaaattt ggaactttat caaatctcaa
     2401 tgcttgtttc aactgttttt caaaatccta agacatattt ttttaatgtc aatacgacat
     2461 tagaattatt attttatttg gaaaatatcg gtcttgcaag agaagagatg gacaggcgtt
     2521 tgaaggatat gcttgagata ttcccgataa aaaatctttt gaacagaaat atatttaatc
     2581 tatccggcgg tgaaaaacaa attctttgca ttgcagcttc ttatatagca ggtacaaaga
     2641 ttatagttat ggatgagcct tcatcgaatt tagatattaa aagcataagt gttttggcaa
     2701 agatgctaaa gatattaaaa gagaaaggca taagcataat tgttgcagag catagaattt
     2761 attatttgat ggacatagtt gaccgtgtat ttttaataga taaaggaaag cttaaaaaaa
     2821 cttatactag aagtgaattt ttaaagctag ataaaaatga attaaatgct ttaagtttaa
     2881 gagataaaga attaagtaaa ttaaaagttc cttatttaaa agaaggtgga gagtatcaga
     2941 taaaaaatct tagctacaaa tttactgatg atgagtgttt aagcttaaaa gatatttcgt
     3001 tcaagcttgg gaaaatttat ggcataatag gatccaacgg acgaggaaaa tcaacgcttt
     3061 taagatgttt aataggtctt gagaaaaaat caaaagaaga aatttatttt aagggagaga
     3121 agctatctaa aaaagaaaga ctcaaaaact cttcacttgt tatgcaagat gtaaatcatc
     3181 aattattcac agatgaagta ttcaacgagc ttagattagg agtaaagaat tttgatgaag
     3241 aaaaggcgaa aatcatctta aaagatttag gcctggacga atttattgaa aggcatccga
     3301 tgagtttatc aggagggcaa aagcaaaggc ttgcaatagc atctgttatg tgcaagaatt
     3361 ctccatttgt cttttttgac gaaccttcaa gtggtatgga ttattccaat atgataaaaa
     3421 tatctgaact gattaataag tataaaacca tggataaaat aatttttatt gtttcccatg
     3481 atatagaatt tttaaatgaa gtggcagatg aaatttttga attgtaaaat agagtc
//
LOCUS       DAVLIK010000097         3344 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLIK010000097 DAVLIK010000000
VERSION     DAVLIK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.097"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(181..714)
                     /locus_tag="VXE87_002088"
     CDS             complement(181..714)
                     /locus_tag="VXE87_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0843548.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(803..1579)
                     /gene="recX"
                     /locus_tag="VXE87_002089"
     CDS             complement(803..1579)
                     /gene="recX"
                     /locus_tag="VXE87_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0843549.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1617..2972
                     /gene="rlmD"
                     /locus_tag="VXE87_002090"
     CDS             1617..2972
                     /gene="rlmD"
                     /locus_tag="VXE87_002090"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0843550.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            3034..3105
                     /locus_tag="VXE87_002091"
     tRNA            3034..3105
                     /locus_tag="VXE87_002091"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3067..3069,aa:Glu,seq:ttc)
BASE COUNT         1085 a          591 c          623 g         1045 t
ORIGIN      
        1 aagacattaa aaaataacag tatatctatt tgttttatat attttacgaa ttttgcataa
       61 atctctttct agtaatgtgt tgtaactctg ctataataga tttattcctt tttgtgttta
      121 cacaatttat tttatactac caaaaaaagg tcaggatttt gttcctgacc tttgacaact
      181 ttaccgattc tttagttcta catagcgctt gtaccaaatg tttacatagg cttctgagaa
      241 aggaccacgt ccattgttaa tccaatcaac aagaattttg acatgttctt ttaaaatata
      301 gtccaagtca tcagaataat tcattttgcg tttgtgacgc tcgtactctt caacgtccaa
      361 gagacgtttt tccccatctg taaaaatttt aacatccaaa tcgtaatcaa tatacttcag
      421 tgcttcttca tccagatagt aggggctagc catattgcaa tagtaagaag ttccattatc
      481 acgaatcatg gcaatgatat taaaccaata tttcttgtga aagtaaacaa tagccggttc
      541 tcgagtgacc caacgacgac catcactttc ggtaacaagt gtatgatcgt tgacaccaat
      601 aatggcgttt tctgttgttt ttagtaccat ggtgtcccgc caagttcggt ggagactccc
      661 atcatgctta taactttgaa ttgtaataaa gtcgccttct tttggaagct tcataactaa
      721 ccaactttct acaatttata agtttatcat ttactattgt accataaaat tacctaaaat
      781 ctgtgaattt cacttggaaa tattaaagat attctctaag agcgcttgct atatccgaaa
      841 aatcgtagcc ctttcgtgct aaaacttgag ttaaacgctg cttcagttcg tatccttcat
      901 actttcgagc atacttagta tattgcttat caagttcctt gaagatgagt tcttgagtcg
      961 tttcttggtc aacttggcta tctaagtcgt caaaggcaat tttagcatca gaataagaga
     1021 agcccttgtt agtcaagttc tggataatct tatcttgcag ggcacgagct ggaagttttc
     1081 cctcatattt tttcaatagt ttattggcta cacgttgagc aacttccgaa aaatcaaaat
     1141 cattcaagat ttcttctata gtagattttg aaattccttt ttgtgctaat ttctgagtca
     1201 gtacataagg tcccttgtct cctgaaagtt gattggcatt gatgatagca taagcgtact
     1261 gaccatcatt aatccactta tcttctttaa gattagcaat aacttgagaa acgatgtttt
     1321 tatcaatatc gtattttttc agatattctc tgacttcttt ttcagtgcgt gctttaaagg
     1381 ataagtggta gagggccaga ttcttaccat aagaaaattg agcaaagtct tgaatctctt
     1441 tcaattcctc ttcgcttatc accttatctc tcgataacat aaaacgaaca attgtatctt
     1501 cggtgatata gcatttgtcg ccattatcaa gctccatcag atagagtctt tttttctttt
     1561 caagttttgt gattttcata gctctattat aactcaaaat gtgataagat aggggtatga
     1621 atctgaaagt gaaacaaaaa ataccattaa aaatcaagcg catgggaatt aacggtgagg
     1681 gaatcggctt ttaccaaaaa acattagtct ttgtaccagg agctctcaaa ggcgaagata
     1741 tctattgtca gattacttct attagacgca actttgttga agcaaaatta ctgaaggtca
     1801 acaagaagtc taaatttcga attgtgccat cttgtactat ttataatgaa tgcggaggct
     1861 gccaaatcat gcacctgcat tatgataagc agctggagtt caagacggac ttacttcatc
     1921 aagcgctgaa aaaatttgct cctgcaggat atgaaaatta tgaaattcgt ccaactattg
     1981 gaatgcagga accaaaatat tacagagcta agttacaatt tcagacccga aaatttaaaa
     2041 atcaggtcaa ggcgggctta tatgcacaaa actctcacta tttagtagag ttgaaagact
     2101 gcctggtaca agataaggaa acccaagtga ttgctaatcg cttagcagaa ttacttactt
     2161 atcaccagat tccaatcacg gatgagagaa aagttctagg tgtccgtact attatggtcc
     2221 gacgcgcgag aaagaccgga caggttcaga ttattattgt tacaaaccgc cagcttaatt
     2281 taactcaatt ggtaaaagag ttggttaaag atttcccaga agttgtgaca gtagctgtta
     2341 atacaaatac agctaaaacc agtgagatat atggtgaaaa gacagagatt atctgggggc
     2401 aagagagtat tcaagaaggt gtactcaatt atgaattttc actatcccct cgagcttttt
     2461 atcaactaaa tcctgagcaa acagaagtcc tctatagcga agcagtaaaa gcgctggatg
     2521 ttgataaaga agaccatttg attgacgctt attgtggagt tggaacgatt ggatttgcct
     2581 ttgcaaagaa agtaaaaaca ctcagaggta tggatattat tccagaagct attgaagatg
     2641 ccaagcgaaa tgctaaaaga atgggatttg acaatactca ttatgaagct ggaacggcag
     2701 aagagattat tcctcgttgg tacaaggaag gctaccgagc agatgctttg attgttgacc
     2761 caccacgtac aggtctggat gataagttat tagatactat tcttacttat gtaccagaaa
     2821 aaatggttta tatttcttgt aatgtttcga ccttggctcg tgatttggta cgcttagtag
     2881 aagtctatga tcttcattat atccagtcgg tcgatatgtt cccacataca gctcgaactg
     2941 aagctgttgt aaaattaata aaaaaagttt aaaaaaggtg ttgacaaaac ataaaaaggc
     3001 tgtataatag taagagttga aaataacaac tcaggtccgt tggtcaaggg gttaagacac
     3061 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatggta tgttgcgtca
     3121 ggagcacttg atgaaaaaaa gtttaaaaaa acttaaaaat cttcaaaaaa gtgttgacaa
     3181 gtgaaagtgg ctgtgatata ctaatatagt tgtcgcttga gagaagcaag tgacaaagac
     3241 ctttgaaaac tgaacaagac gaaccaatgt gcagggcgct acaacgtaag ttgtagtact
     3301 gaacaatgaa aaaaacaata aatctgtcag tgacagaaat gagt
//
LOCUS       DAVLIK010000098         3319 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLIK010000098 DAVLIK010000000
VERSION     DAVLIK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3319
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.098"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(448..1215)
                     /locus_tag="VXE87_002092"
     CDS             complement(448..1215)
                     /locus_tag="VXE87_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA helicase"
                     /protein_id="HEV0843551.1"
                     /translation="MDNKRLIHAVAGSGKTTKIIETIDPQKRNLILTYTETNQNTIRA
                     KLIEKFGYIPESTFIFGVFESLYSFCLVPYLGKRPKGINFDYKTQGKFDKTAIDNTGR
                     IVQNQLSKSLLRGSLIYKRKEIRFDNSYLDRIDKFFDCIYVDECQDFESDDFDWLLSL
                     SNLNAEVFLFGDYYQKTFSTSRRGNKGKRIHSSFENWLKVISDSGYEIDLSSLSKSYR
                     CPKIVCDFIVDNLAIEILSQREEKLSSQITLIDSQKK"
     gene            complement(1197..2786)
                     /locus_tag="VXE87_002093"
     CDS             complement(1197..2786)
                     /locus_tag="VXE87_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014334739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0843552.1"
                     /translation="MISRIILQNFKRYQNVDFTCNSEVNIFVGENGAGKSTLLYGIGL
                     VLSGSHSQIERSSLSSIINQEAILEFMGTRDINQLPEVFIEIYFDELSTEISSNFNIE
                     GKHNSQKIKAFGLSLKIIPNQDYIAEITSVLNDSKWTVFPFEFYRVEFLTFSGKTYSS
                     YNKPYKFLHSMINTSLIDTQQEIQKRIHEVYLDNISAENRAKVNHQYRINSFNFLKTL
                     RKDELLKENASEFQLHFDESENSFRNSVSAVKNGVDIKNLGQGEKVLLGVENAYSHLK
                     ETVKILLIEEPENHLSFQNLQKLVRMLSSNTGVQVFIGTHSNMIASRLGVDNLLFLDN
                     GQISKLKGLKKDTVRFFKKSTNQNLLNFSLGKKIILVEGNAEYILVEKFFEILHSKKP
                     EEFNVSIISVDGLSFERYLEIATNFTDKKVVVITDNDGDYESKVQSKYSSYQQFQNIK
                     VSSDLDNDNRTFEICIYNCNSDLLESSGLTKSNDLLEYMLREKAEFALRLLEQMETDN
                     IREKFIIPNYIKEAIEWIIKD"
BASE COUNT         1140 a          577 c          398 g         1204 t
ORIGIN      
        1 ataacttatc cttacacccc aatgcaacaa gacttgtgga atattactga taaagcaaat
       61 aagaattgga atctccaaaa aaattgatat aatatactgc catttcattg gtctttttat
      121 aaataaaatt ttaactattc tcatattctc tcctaatttg atatttccct tacatcatct
      181 tcctatattt ttctatatcg gattgcttta caaaatataa gttccccctc gtacgtgtac
      241 acgcaacgta aaatttactt ttggtttgtg aagaaagttc attcaagaga tcagctgcga
      301 ataatttgta tgatgttgga tttaatacta cacaaacatt gtcatattca gagcctttac
      361 tatcccccca attctgactc ttgcattcat aatcataaga tttttgataa aaaagtttca
      421 taatattgtc atctgtcatt attgattcta ttttttctgt gaatcgataa gagtaatttg
      481 ggaagatagc ttttcttctc gctgtgataa aatttcaata gctaaattat caacaataaa
      541 gtcacaaact attttgggac aacgataact ttttgacaaa ctcgataaat caatttcata
      601 tcctgaatca gaaataactt ttaaccaatt ctcaaaactc gaatggatcc tttttccttt
      661 attacctcgc cttgaagtac taaaggtttt ttgataataa tctccaaata aaaatacttc
      721 tgcattaaga ttacttaaac ttaaaagcca atcaaaatca tctgactcaa aatcctgaca
      781 ctcatctaca taaatacaat caaaaaattt atcaattcta tccaaatatg aattatcaaa
      841 tctaatttct ttcctcttat agattaatga accccttaat agagatttag aaagttgatt
      901 ctgaacaatt cttccagtat tatctatagc agtcttatca aattttcctt gagttttata
      961 atcaaaattt attccttttg gtcgtttccc taaatatggc actaagcaaa aactataaag
     1021 agactcaaaa acaccaaaaa taaaagtaga ctcaggaatg tagccaaatt tttcaatcaa
     1081 ctttgctctg attgtattct ggttcgtctc tgtatacgta aggataagat ttcttttttg
     1141 aggatcgatg gtttcaatta ttttagttgt tttgccactt ccagcaacag catgaatcaa
     1201 tcttttatta tccattcaat cgcctcttta atataattgg gtataataaa tttttccctt
     1261 atattatcag tttccatttg ttctagtaat ctcagtgcaa attcagcctt ttccctgagc
     1321 atgtattcta ataaatcatt agatttggtt aatcctgaag actctaataa atccgagtta
     1381 caattataaa tgcatatctc aaatgttcga ttatcattat ctaaatcaga agaaactttt
     1441 atattctgga attgttgata agaactatat tttgactgta ctttactttc gtaatcacca
     1501 tcattatccg tgataactac tactttttta tcagtaaagt tagttgcaat ttctaaatac
     1561 ctctcaaaac ttaatccatc tacagaaata attgatacat taaattcttc aggctttttg
     1621 gagtggagta tttcgaaaaa cttctctact aaaatatact cagcattccc ctcaacaaga
     1681 attatcttct tacctagaga gaagttcaat aaattttgat tagtagattt cttgaaaaat
     1741 cttacagtat cttttttcaa acctttaagt ttagatatct gaccattatc taaaaaaaga
     1801 agattgtcta cacccaatct tgaagcaatc atatttgaat gagtcccaat aaaaacttga
     1861 acacctgtat ttgagcttag cattctaacc aatttctgga ggttttggaa gctcaaatga
     1921 ttctcaggtt cctcaataag tagtatttta accgtttcct tgagatgact gtatgcattt
     1981 tcaacaccta ataatacctt ttctccttgc cctaaatttt ttatatctac accatttttt
     2041 acagctgata ctgaatttct aaatgaattt tctgattcgt caaaatgaag ttggaattct
     2101 gaagcattct ccttcaacag ttcatccttc cttaaagtct ttaaaaaatt aaatgaattt
     2161 atcctgtatt gatgattaac ttttgctcta ttctcagctg atatattatc caaatatacc
     2221 tcatgaatac gtttttgaat ttcttgttgt gtatcaataa gacttgtatt tatcattgaa
     2281 tgtagaaact tatatggttt gttgtaagag gaataggttt tccctgaaaa tgtcaaaaat
     2341 tcaactctat aaaactcaaa tggaaagact gtccatttac tatcatttaa gacagaagta
     2401 atttcagcta tataatcttg attgggaatt atttttaatg aaagtccaaa agctttgatt
     2461 ttttgagagt tatgtttccc ttcaatattg aagttagagg aaatttcagt acttaattca
     2521 tcaaaataaa tctcaatgaa gacctcaggg agctgattta tatcccttgt acccataaat
     2581 tctaaaatcg cttcttgatt aatgatacta gacaaactac ttctttcaat ttgactgtga
     2641 ctaccactca gcactaaacc aattccgtat aatagagttg atttcccagc accgttctcc
     2701 ccaacaaaaa tattaacttc agaattacaa gtaaaatcaa cattctgata acgtttaaag
     2761 ttttgtaata ttattcttga tatcatacag actacctaaa cctcgcatat tagtttgaat
     2821 agttatctat taatattata tcacataaat ggtgttaatt tttcaaaatt gtaattacag
     2881 ataagatgaa tattgcttta ttcttgcatc ttaaaaagat tttgacataa ttgttgcata
     2941 ataaagcaat aggagcttta gcttatattt tctagtattc gtcttaaaga acaccaaata
     3001 gataaacact attcctaatc tgagctatct aatctattaa aaatcaatag aacttcatac
     3061 aacaagtggt aaagtagtaa atccgttcca gatcaaaaaa ctcattctgc tcttgcaaga
     3121 acacttgatg ttccaacaac atattttgaa tcagtataca agattatgat cccctatctt
     3181 cagctctctt caaaaaatta agattctgat gctgaaaaaa gaagaatcct tgattttatg
     3241 agtctagtaa atagtgaata cccaattgat gaaagtttta attatcaaaa ctatatttca
     3301 aatgcagaaa ttccagcaa
//
LOCUS       DAVLIK010000099         3243 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLIK010000099 DAVLIK010000000
VERSION     DAVLIK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.099"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(191..802)
                     /gene="rpsD"
                     /locus_tag="VXE87_002094"
     CDS             complement(191..802)
                     /gene="rpsD"
                     /locus_tag="VXE87_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0843553.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(997..2049)
                     /locus_tag="VXE87_002095"
     CDS             complement(997..2049)
                     /locus_tag="VXE87_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0843554.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2046..2744)
                     /locus_tag="VXE87_002096"
     CDS             complement(2046..2744)
                     /locus_tag="VXE87_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0843555.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2911..>3243)
                     /locus_tag="VXE87_002097"
     CDS             complement(2911..>3243)
                     /locus_tag="VXE87_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0843556.1"
                     /translation="INVKETSDTANGSLSPSNSGSSVTPMNHNHAPGTTDSVPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT          908 a          729 c          622 g          984 t
ORIGIN      
        1 ttgaatatgc cataaaagga ttataccaca ttgtgtacta tttttggttc attttactat
       61 atcactttgg actatatcgg tctagttatg tctcaacgat tatagctgga tactaagaga
      121 aatcaaaaaa gcactaaggg agaacgtccc aaagtgctta atatcaaagc ctatcttatt
      181 caataaaata ttacaacatt ttgttgtaga attcaacgac aagtgcttcg ttgatttctg
      241 ggttgatttc gtcgcgttct ggcaagcgag tcaatgaacc ttccaacttt tcagcgtcga
      301 atgatacgaa tgctggacgt ccaagagtag cttctactgc ttcaaggatt gctggaactt
      361 tcaatgattt ttcacgaact gagattactt gacctggagt tacgcggtat gatgggatat
      421 caacgcgttt cccgtcaaca aggatgtgac cgtggtttac gaattgacga gcttgacgac
      481 gagtagtcgc gagaccaaga cggtaaacaa cgttatccaa acgacgttcc aaaagaagca
      541 taaagttgaa acctaggatt ccgcctttga tttttgtagc ttgtacgaac aagttacgga
      601 attgtttttc acctacaccg taagtgaaac gaagtttttg tttttcagcc aattgcaaac
      661 catattctga caatttagaa cggttgtttg gtccgtgttg tcctggtacg tagttacgac
      721 gtgccaattc tttacctgta cctgtaagtg aaaggccaag gcgacgagct tgtttccaag
      781 atggtcctgt ataacgtgac atatgaatgt cctcctgata taaataatat ttcggtggaa
      841 atagtcactt agaaagccct gattcgtgca gatgcccttc gcctaaacag ccaaggttac
      901 ttgtcataag acacctgttg acgagcttca tgctttcctg ctgatatttc acacaaaatc
      961 cattttacca tgaatagctg gatttgtaaa ggggttttag gctttatttt cactaccaga
     1021 gagattgaga acgagggtaa aggtacttcc tagaccgtac tggctgctga ctgtgatttc
     1081 cccacccaat tgatgggcca attcacgcgc aatcgcaagt cctaatccat gaccacctgt
     1141 cttcatgtta cgcgaagttt cgacacgata aaggcgtttg aaaatatttt ccaaatcctc
     1201 tggggcaatg ccctgccctt catcggtcac actgattgaa agctggccct tctccagctt
     1261 agtcaccact tccagcttgg ttcctggagc agaatattta aaagcgttat cgaccagatt
     1321 caccaagata cgagaaagct tagcataatc tccctcaatc cgggcagact ctgggattac
     1381 ctgcaagtgg acatctcttc tctcctgctc aatcaaaaac tgaaattcac tcatgcactc
     1441 aattaagagc ttgtccagaa aaatactgtc tttactggta gtttccacct gatttctagc
     1501 tgtgtttagg gtcaaaaaat tcaactcctc aaccagttta ttgagcctct ccgtctggcg
     1561 tccaatggtt gctagataat gagcttgctc cgactccttg ataatcccat ccaaaatccc
     1621 ttctaccgtc gcttggatcg aagtgatagg ggtcttaata tcatgcgaca actgagcaat
     1681 catcaagccc ttttctcgtt cgctttcttc caaggaatca aagcttacct gcaaatcatg
     1741 ggacatctca ttaaaagttt gccctaattg ctgaaattct acaggacctt gaacctccaa
     1801 atttgaagga aaatccttgg ccgctacccg cttggcatgc tccttgagtt tgcccaacga
     1861 cgtaaagact ggcaatagga gaaagagact aatcccagca ccgacaaggc tggcaacgat
     1921 ggtcatccca agcaaaaagt aaatctcgcc tttcgcaatc agcatttttt gaacagccca
     1981 aaaaacaacc aaaatggtta agagggttga aataatatat ccaaccaaaa tataactttt
     2041 tagtttcatg tttgtcctct cggtttctct atcttatatc ccaaccccca aactgtctta
     2101 atagtgggag tttggtcact actatatttt gccagctcct gtcgaagagc atggatatgc
     2161 acattcaagg tattggtgtc atccacgtag tcttctttcc agatcttttc atagaggtct
     2221 gtcttggaga aaactcgctc tggattgcta gctaaaatcc acagcaattc aaatgattta
     2281 acagttaaat ccagcatttc ttctcctatt tgaacttcat gactactatg attcattttt
     2341 agattgccaa gggaaatcag ctctgtttcg cccccacgat gaaggcggcg caaaatattg
     2401 tggacacgca aaaccagctc acgtgggcta aaaggcttag caataaaatc atctgctccc
     2461 aagctcaggc cgtaaatctt gtcctgttca ctggtcttag cagtaataaa taggaaaggc
     2521 tgctctggtg ataagtattg aacctcactg attaaatcat aaccatccat ccgaggcatc
     2581 atgacatctg tgataatcaa atcaatcggt tttttcttga acagctctag cgcttccagt
     2641 ccatcatggg ctaccaagac ctgataacct gcctgaatta agtatctctg atgaatatct
     2701 gtgatttcta cctcgtcgtc aacgagtaaa attgtctttc ccatctgtct ctcctttgat
     2761 aaaaacagtg ctatactgct ttaagtataa cactattttt attgttttac gatgatttta
     2821 atctgctatt gaaagaaagt cctgattgct gattgagttg ttaaactaat cttagtcagc
     2881 ccactatcca tcatttattt ccttagctga ttagttttct tcttttttgt ttttcaaacc
     2941 tagaccaccg agtaaacctg caagcgcaag cccaaggaaa ccaatacttg ccattgatgt
     3001 ttgagtctca ccagtatttg gtagcatagc tttatcctct gacatcatcg tatcagacat
     3061 cttgttagca gaagcagcca tgttttcacc tgccatcgtg ttggtagaac ttgtcatggt
     3121 gtcagcaggc acgctatctg tagtacctgg agcatgattg tgattcatcg gagtcacgct
     3181 agaaccagag ttagaaggtg ataatgaacc atttgctgtg tctgatgttt ctttaacatt
     3241 tat
//
LOCUS       DAVLIK010000100         3174 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLIK010000100 DAVLIK010000000
VERSION     DAVLIK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3174
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.100"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..803
                     /locus_tag="VXE87_002098"
                     /pseudo
     CDS             1..803
                     /locus_tag="VXE87_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            851..1273
                     /locus_tag="VXE87_002099"
                     /pseudo
     CDS             851..1273
                     /locus_tag="VXE87_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1485..1877)
                     /gene="rpsI"
                     /locus_tag="VXE87_002100"
     CDS             complement(1485..1877)
                     /gene="rpsI"
                     /locus_tag="VXE87_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0843557.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(1896..2342)
                     /gene="rplM"
                     /locus_tag="VXE87_002101"
     CDS             complement(1896..2342)
                     /gene="rplM"
                     /locus_tag="VXE87_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0843558.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            2699..3016
                     /locus_tag="VXE87_002102"
     CDS             2699..3016
                     /locus_tag="VXE87_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0843559.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
BASE COUNT         1011 a          613 c          580 g          970 t
ORIGIN      
        1 tcttcttcta aaagccatta aactagctcg ttcgacctac tactatcact tgaaacagct
       61 agacaaaaca gataaggacc aagagcttaa agctgaaatt caatccattt ttatcgaaca
      121 caagggaaat tatggttatc gtcggattta tttagaacta agaaatcgtg gttatctggt
      181 aaatcataaa agagttcaag gcttgatgaa agtactcaat ttacaagcta aaatgcgaca
      241 gaaacgaaaa tattcttctc ataaaggaga cgttggtaag aaagcagaga atctcattca
      301 aggccaattt gaaggctcta aaacaatgga aaagtgctac acagatgtga cagaatttgc
      361 cattccagcc agtactcaaa agctttactt atcaccagtt ttagatggct ttaacagtga
      421 aattatcgcc tataatcttt caacttcacc caacttagaa caagtacaaa caatgttgga
      481 acaggcattc aaagagaagc actatgagaa tacgattctc catagtgacc aaggctggca
      541 ataccaacac gattcttatc atcggttcct agagagtaag ggaattcaag catccatgtc
      601 acgtaagggc aacagcccag acaacggtat gatggagtcc ttctttggga ttctgaaatc
      661 ggaaatgttt taagtcgttt cagtcgctta agcaattgga acaagctatt gtagactata
      721 ttgattacta caacaataag aaaattaaga taaaactaaa aggacttagt cctgtgcaat
      781 acagaactaa atccttcgga taaattaatt gtctaacttt ttgggggcag tacataagaa
      841 ccttggtaat atgcgtttta ttatggcaac atttcccatt ttctctattt ctaatgactt
      901 acttcaactc cttacctctt ggaaagaaca acaaagatat gaactagcaa agtttggcat
      961 cctcagtaat ccagaacaat ttgtttttac atatatcgac acaaaaggaa acatcaacaa
     1021 gcctttacat gccgactatc tgaacaataa aatgaaaagc attagaaagc gacataaaga
     1081 actgacacac gctacacctc acaaattacg ccatacaggc gcaactctag ctaaataagc
     1141 aggaatgagc ttagaagcca tttctgaagc actaacgcat agcgatacag gcacaactca
     1201 aatttatgtc aacacctcta atgtagttcc tatgacagta ggtgaatttg ctttaaagtc
     1261 tctaaaacaa taaggtatag tagattgaaa ctagaatagt acacctctac ttctaaaaca
     1321 ttgttagaat tcgatttgac tgtcctgatc gatttgtcct attcttattt catttcgcta
     1381 taaaaataag gtaaactttg agataaactt ttcaaaaaaa cacgaaaaaa gcacccataa
     1441 ggtaaacttt tgagtgcttt gaaacgttga tataatcgta ttgattaacg tttactaaat
     1501 tgtgatgctt tacgagcttt cttaagacct ggtttcttac gttcaacttt acgtgagtca
     1561 cgtgtaagaa gtcctgcgcg tttcaatgaa tcgcggaagt ctgggtctac ttgaagaagg
     1621 gcacgagcga taccgtgacg gatagctcct gattgaccag cgtatccacc acctacaacg
     1681 ttaacgaaaa cgtcgtatga acctacagtt gaagtaactg cgaatggttg gttgatgaca
     1741 agacgaaggt cagcgtgtgg gatgtactct tcaacatctt ttttgttaac agtgatttta
     1801 ccagttcctg gaacaaggcg aacgcgtgca acagcgtttt tacgacgtcc agtacctgca
     1861 tattgtgctt gtgacatact ttattgttcc tttccttaga taagtcctga aatgtcaaga
     1921 acttctggtt gttgtgcagc gtgagtgtgc tcagctccaa caaatacttt caacttcata
     1981 ccttgagcgc gtccaagtgt attgtgtgga agcatacctt taactgattt ctcaatcaaa
     2041 cgtactgcat ttttagaacg aagttcacct gcagagattt gtttcaatcc acctgggtgg
     2101 tttgagtgag tgtagtagat tttatcagtt gcttttttac cagtcaattt aactttttca
     2161 gcattgataa caatcacgaa gtcacctgta tcagtgtgtg gtgtaaatgt tggtttgttt
     2221 tttccgcgaa gtacgctagc aactactgca gaaagacgtc caagtggtac atcagttgcg
     2281 tcaactacgt accatttacg ttcaacttgg cctggtttag ccataaatgt tgttttgttc
     2341 atgatttctc ctatatatag ttcgattttt gtttacggtg atgggtgttc cttcccatcg
     2401 aaaagtattt ggaaggttcc ggggcctttc aaatggggta aacaataccg cctactatca
     2461 taccaaattt cacccctaaa agtcaataga tatgaaaaat atttttcggt aacttctcaa
     2521 agtaactgaa agttatataa tcaagttaat ttgggaattt acctattaac ttcggtagat
     2581 ttttgagaat ttttttcctt ctttttcctt gtagttaaaa tccttttcaa aaaatcacct
     2641 tttcttgatt tttaatccta tttgctgtat gataagggaa aagaaagggg acagagatat
     2701 ggcttttacc aatacccaca tgcgatctgc tagttttggc attgttacca gcttgcctga
     2761 tgacatcatt gactcttttt ggtatattat cgaccatttc ttaaaaaatg tctttgaatt
     2821 ggaagaagaa ctcgagtttc aattgcttaa taaccaagga aagattacct tccacttttc
     2881 aagtcaacac ctccctacag ccattgattt tgactttaac catcctttcg accctcgtta
     2941 tcccccaaga gtactggttt tagacatgga cggtagagaa actatcctcc tcccagaaga
     3001 aaatgaccta ttttaatact taatgaaaat caaagagcaa actaggaagc tagccgcaag
     3061 ctgtacttga gtacggtaag gcgacgctga cgtggtttga agagattttc gaagagtata
     3121 aaaactctag ccttcagttg caagtaactg aaaactagag tttttctatt tttt
//
LOCUS       DAVLIK010000101         3139 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLIK010000101 DAVLIK010000000
VERSION     DAVLIK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3139
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.101"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(1..650)
                     /locus_tag="VXE87_002103"
                     /pseudo
     CDS             complement(1..650)
                     /locus_tag="VXE87_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1101..1793
                     /locus_tag="VXE87_002104"
                     /pseudo
     CDS             1101..1793
                     /locus_tag="VXE87_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(2027..2323)
                     /locus_tag="VXE87_002105"
     CDS             complement(2027..2323)
                     /locus_tag="VXE87_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000941983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843560.1"
                     /translation="MLQSPYAIDTINLKKDFLEKPIDIEKFKAFLEKEEIPLAIAWQG
                     DSLHFYTKDRSILDNHLDHLLEKMVNDPEKLSDFSMDKSLDDAIDEAKSQITFK"
     gene            complement(2336..2479)
                     /locus_tag="VXE87_002106"
     CDS             complement(2336..2479)
                     /locus_tag="VXE87_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000093669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843561.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKGLLKILEWSRRQALEQDSAYK
                     IGV"
     gene            complement(2481..2769)
                     /locus_tag="VXE87_002107"
                     /pseudo
     CDS             complement(2481..2769)
                     /locus_tag="VXE87_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          992 a          606 c          538 g         1003 t
ORIGIN      
        1 ggttataggc tttatcttca gctattagcg gcttgagttt gctggattta cgtggagttt
       61 gtgcttgagg atatatcttc atgagccctt gataaccact gtcagccaag attttaccag
      121 cttgtccgat atttctgcga ctcattttga acaacttcat atcatgacaa tagttcacag
      181 tgatatccaa agaaacaatt ctcccttgac ttgtgacaat cgcttgagtc ttcatagcgt
      241 gaaatttctt tttaccagaa taattcgcta attctttttt taggtcgatt gatttttact
      301 tccgtcgcat caatcattac cgtgtcctca gaactgagag gagttcttga aatcgtaaca
      361 ccacctttga acaagagtta cttcaaccca ttggctccga cggattaagt tgctttcgtg
      421 aataccaaga tcagccgcaa tttgttcata agttcgatat tctcgcacat attgaagagt
      481 ggccataaga aggtcttcta ggcttaattt aggttttcgt ccaccttttg cgtgtttaag
      541 ttgataagct gttttaatac agctaacatc tcttcaaaag tcgtgcgttg aacaccaaca
      601 agacgcttaa atcgtgcatc ggttagttgt ttacttgctt catcattcat agaactatta
      661 taccatattt tgtttcgcag gaagtctatt gaaaaatctc cagactggag aactcacgga
      721 tagttcctaa tctggagatt tcttatttgc acttttcttg tacaacttta gtccatggta
      781 aataagcctc taaaacctct ttgtttacga gagtttcctc gtttggaaga cattctagaa
      841 gataggatag atatttctcg ctatttatac cagactaaaa tcaaaaagca ttatataata
      901 gtgatatgaa atcaactaaa gaagaaatcc aagccatcaa aacactttta aaagactctc
      961 gtacagctaa atatcataaa tgccttcaaa tcgttctata gtaaaacgaa acaagaacag
     1021 ggcaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac
     1081 tattctagtt tcaatctact atatttcgtc tgatgggcaa atcttataaa gagattatag
     1141 aacttttaga ctgtaatcaa acaacgattt agcgaaatgt aaaaaatatg aggagttcgg
     1201 actcgactct ctctttcaag aaacacgtgg tggtcgtaac catcatatat gacagttgag
     1261 gaagagaaag cctttcttgc ccgtcatttg aaggctacag aggcaggaga atttgttaca
     1321 attgatgcct tatttcaggc ttataaaaag gagttaggtc gttcctacac acgtgatgcc
     1381 ttctatcaac tgttgaagtg ccatggttgg cgaaatatta cgccacgtcc agaacatcct
     1441 aagaaagcag acgctcaaac cattgtcgcg tctaaaaata aaatctcaat tcaagaagac
     1501 aagaaagcgc tttaaaatca gtagacgttt tcgtaaggtt cgcttgatgt accaagatga
     1561 ggctggtttc agtagaatca gtaaactggg atcttgttgg tctccaatag gagtaggttc
     1621 acatgtccat agtcactata tacgagaatt tcgctattgt tatggagctg ttgatgccca
     1681 tattggaaga tgtcatgaat caacttcaag atgtcataca aggactggag aaggaggtga
     1741 taaagtccat cgttaatcgg agatggacta gaatgctttt tgaaaacaga tgagtattag
     1801 aaataaatga aaagtcaata tcaaaacaat cagaatcttg atgatgctaa attcaaaaaa
     1861 actacataat aattttaata agggtaagtc gtaccaagaa accccaccaa gataaaaact
     1921 tagtggggtt tggcggggaa tataattatt ctcccaatta ttatcgcctt tatattatct
     1981 caactctcat taaacaagag ttccgcaatc aaattgcgat actctattat ttaaaggtaa
     2041 tttgggattt agcctcatca attgcatcgt ctaatgactt atccatggaa aaatcagata
     2101 atttctcagg atcattcacc attttttcta acagatggtc taaatgattg tctagaatcg
     2161 aacggtcttt cgtgtagaaa tgcagagaat ccccttgcca agcgatggct aaaggaatct
     2221 cttctttttc taaaaaagct ttaaatttct ctatatcaat tggtttttct aaaaaatctt
     2281 ttttcagatt aatcgtatca atcgcatagg gagattgtag caattcttct aatttctaca
     2341 cccctatctt ataggcggaa tcctgttcta aagcctgacg tctagaccat tctagtatct
     2401 ttaaaagacc ttttacagta aataaaagac tacgctcagc atattgaact gccattcgtt
     2461 cctgttgttc agaggacatc tcagacctcc ttcttaacaa atagcagctt tccttcttta
     2521 taacgataag ctatcaattt ctgacgttgc ttaatcgact tgacaacctg cagtagatct
     2581 ctcgaataag gttctcgaag agtaacttct actgctttcc catcaaagat accaacacgt
     2641 ttaaactcaa tgtagtcttt tttgagatgt cctaagccca taccaaaagg aaagtgatga
     2701 atcaattgga tggtacaacc aacctttatt tcccatttgt ttcaaatcat acaagtttac
     2761 taccttcatg attaactcct ttatctagtt tgtcgcatcg tttgagtctg gaaacgataa
     2821 actccgtgtc tgttagaaaa ttctcacaca cgtcttgtgc cagttgccct tcacaggaaa
     2881 atactctcag tccctactta cacaggcacg ctaatcaaga cggagtggat tcaattttca
     2941 aagaacaggt agctttatta tagaattgaa gatttaatac ttcttctgcc atagctagct
     3001 cctcctattt aaatttttgg gattaagtac tttatccacc ctcattatat tctctccacc
     3061 agtaaaatgc aagcacttat acaaaataga tttaactatt ttatatagcg aaaacttaca
     3121 aatttttaag aaataattt
//
LOCUS       DAVLIK010000102         3080 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLIK010000102 DAVLIK010000000
VERSION     DAVLIK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3080
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.102"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..1509
                     /gene="rlrA"
                     /locus_tag="VXE87_002108"
     CDS             <1..1509
                     /gene="rlrA"
                     /locus_tag="VXE87_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HEV0843562.1"
                     /translation="KRITDKITILNILLDIRSIELDELSTLTSLQSKSLLSILQELQE
                     TFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQSFNEFTQ
                     KEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFGIEIYDLN
                     DGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFPESKEFEK
                     LKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWNQEKKTHT
                     IQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVPYYNYYEH
                     YGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLPAIPIFII
                     LNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTKEYLPYVK
                     KQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYLL"
     gene            1774..3036
                     /locus_tag="VXE87_002109"
     CDS             1774..3036
                     /locus_tag="VXE87_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0843563.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGAFPSLIRLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFIRYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGY
                     RNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         1017 a          646 c          476 g          941 t
ORIGIN      
        1 aaaagaatta cagataaaat taccatttta aatatattat tggatattcg gtctattgaa
       61 ctagatgaac tgtctacttt aacttcatta caatctaaaa gtctcctaag cattttgcag
      121 gaattacaag aaacattcga ggaagagttg acatttaatt tagatacgca acaagttcaa
      181 ttaatcgaac accattctca tcaaacgaat tattacttcc atcagcttta taaccaatca
      241 actattttaa aaatactccg cttctttcta ctacaaggta atcaaagctt taacgaattt
      301 acacaaaaag agtatatttc catcgcaaca ggctaccgcg tacgacaaaa gtgtggcttg
      361 ttactacgtt cagtaggttt ggaccttgtg aaaaatcaag tagttggtcc tgaatatcgc
      421 attcgttttt taattgcact cctccagttt cattttggta ttgagattta tgatttgaat
      481 gatggaagta tggattgggt cacacatatg attgtgcagt ctaattctca actcagtcat
      541 gaactgttag aaatcacacc tgacgagtat gttcatttta gcatactagt ggcactcact
      601 tggaaacgtc gggaatttcc acttgagttc cctgagtcca aagagtttga aaaattaaaa
      661 aacctcttta tgtatccgat tttgatggaa cattgccaaa cttacttaga gccacatgcc
      721 aacatgactt ttactcagga agaactggat tatatctttt tggtttattg ttctgctaat
      781 tcttcgtttt ccaaggacaa atggaatcaa gaaaaaaaga ctcatactat tcaactgatt
      841 cttcagcata caagaggaaa gcatctacta tccaagttca agaatatctt aggaaatgac
      901 atttcgaatt ctctttcttt tttaacagca ctgactttct taacaagaac gtttttgttt
      961 ggtttacaaa atctagttcc ctattataat tattacgaac attatgggat tgaaagcgac
     1021 aagccactgt atcatatttc gaaagcaatt gttcaagagt ggatgactga gcagaagatt
     1081 gaaggagtta tcgaccagca tcggctgtac cttttctcac tctacttgac agaaaccatc
     1141 ttttcctcac tacctgctat cccgattttt atcattttaa ataatcaagc agatgtaaac
     1201 ttaataaagt ccattatttt acggaatttt actgacaaag ttgcctctgt tacaggatac
     1261 aatattctaa ttagtcctcc tccttcagag gagcatttga cagagccatt gattattatt
     1321 acaacgaaag aatacctgcc ttacgttaaa aagcagtatc ccaaagggaa acatcacttt
     1381 ttgacgattg ccttagattt gcatgttagc caacagcgtc tcatctatca gacaattgta
     1441 gatatccgaa aagaggcttt tgacaaacgg gtcgcaatga ttgctaaaaa ggctcactat
     1501 ttgttataag ttcatcgtac tgtctacaca caaaaagggg cttcctaagc catctctatt
     1561 cttatcccca tatttcccag ttttgggtaa atctgaacag aaaaacactt ctgctctcta
     1621 gtttctgcta gtgaacaaaa gtgttttttc tggctctata atttctgtag tgggtaaatc
     1681 ccactgtgga gattataggg ctttttgagt atcaaaaaag tcccataaga cttataatga
     1741 aaagcgccta aacaactcat tagaaagtat cttatggaac acatcaatca taccacatta
     1801 ctcatcggaa taaaagacaa aaacatcacc ttaaataaag ccattcagca cgatacccat
     1861 atcgaagtct tcgctacact tgattatcac ccacctaaat gtaaacactg taaaggaaaa
     1921 caaatcaaat acgacttcca aaagccttct aaaatccctt ttatcgagat tggtgctttc
     1981 cctagcctca ttcgtttgaa aaagagacga tttcaatgca agtcctgtcg gaaagtcact
     2041 gtagctgaaa caactctcgt tcagaaaaat tgccaaatct cggaaatggt gagacagaaa
     2101 attgcccaac tcctactcaa cagagaggct cttacacata tcgcttctaa attagccatc
     2161 tctacctcta cctctaccgt ctatcgtaag ctcaagcaat ttcatttcca agaggattac
     2221 accactttgc ctgaaatcct ctcctgggat gaattctcct accagaaggg gaaattggct
     2281 ttcattgctc aggatttcaa cactaagaaa atcatgacca ttcttgataa cagacgtcaa
     2341 acaaccatcc gaaatcattt cttcaagtac tcgaaagaag ctagaaaaaa agttaaagtc
     2401 gtcactgttg atatgtctgg aagttatatc cctctcatta agaaattatt tcccaatgct
     2461 aaaattgttc tcgatcgttt ccacattgtc caacacatga gcagggctct taatcagact
     2521 agaatcaaca tcatgaagca atttgatgat aaatctctgg aatacagagc tcttaaatat
     2581 tactggaaat ttatcctaaa agatagtcgg aaactctctc ttaagccttt ctatgctaga
     2641 actttcagag agaccttaac tcctagggag tgtctgaaga aaatctttac tctagtacct
     2701 gaacttaaag attactatga cctgtatcaa ctactcctat ttcatctaca agagaagaat
     2761 actgaccagt tttggggctt aattcaagac acgttacctc atctcaaccg cacctttaaa
     2821 accactttga gcacatttat tcgctataaa aactacatca ctaacgccat tgaattgcct
     2881 tattctaacg ctaaacttga ggccactaac aaactcatca aagacatcaa gcgcaatgcc
     2941 tttggttatc ggaactttga aaacttcaaa aaacggattt tcatcgctct gaacatcaaa
     3001 aaagaaagga caaaatttgt cctttctcga gcttagcttt tcttcaaccc actacagttg
     3061 acaaagagcc ctttttatta
//
LOCUS       DAVLIK010000103         2764 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLIK010000103 DAVLIK010000000
VERSION     DAVLIK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.103"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..393)
                     /locus_tag="VXE87_002110"
     CDS             complement(<1..393)
                     /locus_tag="VXE87_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843564.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCIGDFPHDFFDTYLDHVAKYAYEQ"
     gene            complement(407..1120)
                     /locus_tag="VXE87_002111"
     CDS             complement(407..1120)
                     /locus_tag="VXE87_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0843565.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1579..1953)
                     /locus_tag="VXE87_002112"
     CDS             complement(1579..1953)
                     /locus_tag="VXE87_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV0843566.1"
                     /translation="MESIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGGIG
                     TSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNAAA
                     LLQAGAELSVIQTQLAELEINK"
     gene            complement(2372..>2764)
                     /locus_tag="VXE87_002113"
     CDS             complement(2372..>2764)
                     /locus_tag="VXE87_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0843567.1"
                     /translation="DHVQRNKNDQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKENK"
BASE COUNT          844 a          540 c          439 g          941 t
ORIGIN      
        1 ttgttcgtag gcatattttg ctacatgatc taggtatgta tcaaaaaagt catgaggaaa
       61 atctcctata cagccattac gattcatatt gaggctatat tttcgattag taagataatt
      121 cggaaatata tttcctatta ctctaagatt atctacttgt gaatcccttc tcccaatata
      181 atccccttct ttgactaatg atggagattt ccaagtaaaa attaaatcgc cagagaaatt
      241 tttcttatca aaaaacttaa aaagagattg ataaatacta tttgctaatt gacaagtgtc
      301 agatgtaaat tcataattaa cagcttcatt aaaatcaact tcagacattt caatgtactc
      361 ttcaatagta atattagctt tttttgtagt cattagctaa tctcctttaa aatgtgatct
      421 tttcaagaat atttttatct aaacaatcca gcaagtcttg gtaagaatag acttcgtaag
      481 tcggctgggc ttgtgtgtga ttttcgaggt gatgaggatt ataccagata gtgtcaatcc
      541 ccgcattatt gccaccttga atgtcggcgg ttagagaatc tccaatcatc agcgtctttt
      601 ctttactaaa tccagcaatt tgctggccaa tcttttcata aaagagagca tccggctttt
      661 gagtttgcaa ctgttctgag ataaagactt gattgaaata aggtactaga ccagattgag
      721 ccaaacgtcc tgtctgaatg gcagtaatgc catttgtcgc agcatacaag tcataatcac
      781 gctcaatgag gctgtccaag agatcatgag cgcccgatag tgtttgtccc tgctgagcga
      841 gataaaattg gtaacgctgg gcaagaaaac taccgtcttt ttcctgtcca aaatgagaaa
      901 ataaacgaga aaagcgcgtg ttaaccagct cttgtttact gattttcttc agctccaagt
      961 ctttccagag agccttgttc ataggaacgt aataatcttt ataagcctga atatccgcaa
     1021 ctccttcttc ttttagaagt tgggtcaaag ccacatcctc agcagcatca aaatcaagaa
     1081 gagtgtggtc gaggtcgaag agtagaaatt tgtagaacaa tttgaggttt tcctttctga
     1141 aaattcatta agaacattat atcataaagc acctcataca attaactaat ttaatcactt
     1201 aaaaaaaatt cgaacacttt ctatacaact gacagctcaa atctttcaga atagaacaat
     1261 actaactatc gaacaccccg tcttcataaa tacatatgta attctaggcc tagaattcct
     1321 ataaactaaa tgctttcata ctcttccaag taattgattg ccttaaattt taatttttga
     1381 aggattctaa agctagaata gccccatcac aatcagtttt gattgattca caatttagaa
     1441 acactatagt ttcactcctg ttaaaataaa aaggaactgc ataaagcaat ccctttctga
     1501 ttttgaaatc atttacttaa cattttatag ttgagataat caatagctta cctataaaaa
     1561 gagttatagt aaaattcctt atttattgat ttcaagctcc gctaactgtg tttgaataac
     1621 tgacagttct gcaccagcct gaagaagagc agctgcatta taggcacctt ctacaattgg
     1681 aaccctgttg atgatgatac ttttatcact gaaatcagtc accattttta agttcatttt
     1741 agcagaacct aggtcaaaaa aggcaagtaa agtatctgct ggattttcgg aaacaaccct
     1801 atctacttga tcaaaactcg ttccaattcc tccgccctcg gttcctccta cataagtaat
     1861 cggaacatct ttagctactt tactaatcag ttcaacaaca ccttctgcaa tgtgtttgga
     1921 atgtgaaacg ataacaagac caatactttc catcaaacca ccccagtttc taaaatagca
     1981 gtaaatagta atcctgatga gaatgatcca ggatcgatat gtccaaaaaa ccacatgctc
     2041 ctaagacaag agccaacaga ctggccatca ataatagtat tgttcttttt tatcattact
     2101 ccttaactag tgtttaactg attaattagc cagtaaatag tttaccttta tttacactat
     2161 ctgttaagat atagtaaaat gaaataagaa caggacagtc aaatcgattt ctaacaatgt
     2221 tttagaagta gaggtatact attctaattt caatctacta tattttgcac attttcataa
     2281 aaaaatgaga actagaactc acattctgct ctcatttttc gttttcccgt tctcctatcc
     2341 tgtttttagg agttagaaaa tgctgctacc tttacttatt ctcctttaat aaagccaata
     2401 gtttttcagc ttctgccata atagtattgt tgtcctgggt gccaaatagt aaattatttt
     2461 ttaatcctgt gagagtctct ttggcattgg acttgataat tggatcctgg atttttccaa
     2521 gtaaatcttc agcctctctc agtttttctt caaccttttc agtctcgacc tgaggttctt
     2581 ctgattcctc tggtgattct tcttctggtt cctctgttgg ttttggagac tctggtttct
     2641 cgctttgcgg tttctcttct cgaggggttt cttcctcagg tttttctgtc tgaggtttct
     2701 cctcgcttgg tttttccgtt tgattggtat cagcttgatc atttttgttt ctttgaacat
     2761 ggtc
//
LOCUS       DAVLIK010000104         2716 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLIK010000104 DAVLIK010000000
VERSION     DAVLIK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.104"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            22..726
                     /locus_tag="VXE87_002114"
     CDS             22..726
                     /locus_tag="VXE87_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0843568.1"
                     /translation="MGIKNSRGKYISFLDDDDEYMPDRILKLMACFKKSRMKNLALVY
                     SYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAGTSFWLCKKEVLELINGFEKIDSHQ
                     DGVVLLKLLAQGYQIDIVREFLVNYYAHSKENGITGVTQKTINADEEYYNYCRKYFNL
                     LSFNERILVTKKYYSLNIKRLLLIGDKCKALKVIKKAREEKIFNEFPFLEYMLLYHFG
                     FFYCIYDNYVQLKFRK"
     gene            736..2352
                     /locus_tag="VXE87_002115"
     CDS             736..2352
                     /locus_tag="VXE87_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843569.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKRIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          974 a          314 c          501 g          927 t
ORIGIN      
        1 ggtgcaacta atgccagaaa cataggtatc aaaaattcta gaggtaagta tatatcattt
       61 ttagacgatg atgatgaata tatgccagat cgaattttaa agttgatggc ttgttttaaa
      121 aagagtagaa tgaagaattt agctttagtt tatagttatg gaataataat ttatccaaat
      181 ggtacacgag aagaggagaa gaccgatttt gttggaaatc ccttgtttgt tcaaatggtt
      241 cacaatatag caggtacgtc attttggttg tgtaaaaaag aggtgctaga attaattaat
      301 ggttttgaga aaatagattc acatcaggac ggtgttgttt tattaaaact acttgctcaa
      361 ggataccaaa ttgatatagt gcgagaattc ttggtgaatt actacgctca cagtaaagaa
      421 aacggtatca ctggagtgac acaaaaaaca attaatgcag atgaagaata ttataattac
      481 tgtaggaaat attttaattt attgagtttc aacgagagaa tattggttac aaagaaatat
      541 tattctttaa acataaagcg gttactatta ataggagaca aatgcaaggc tttaaaagta
      601 atcaagaagg caagagaaga aaaaattttt aacgaatttc cttttttgga atatatgtta
      661 ttatatcatt ttggtttttt ctattgtata tatgacaact atgttcaatt aaaatttaga
      721 aagtgagaaa ctattgtgta tactattata aaatcaaata taaaaaaatt tagtttatta
      781 acgatattta ttgttgctgg tcaattattg ctaatttatg cagcaactat taatgctctg
      841 gtgttgaatg aattaattgc gatgaattta gagcggtttt tgaaattgtc aatctaccaa
      901 atgattgtct ggtgtgggat aatattcctt gactgggtag tgaaaaatta tcaggttgaa
      961 gtgatccaag agtttaatct agagattcga aatagagttg ccacagacat ctctaactct
     1021 acctatcaag aatttcatag taaatcatca ggaacatatc tttcgtggct aaataatgat
     1081 gttcagactt taaatgatca ggcttttaaa caactttttt tagtaataaa aggaatttct
     1141 ggtactatat ttgcagttgt gactcttaat cactatcatt ggtcattgac tgtagccacc
     1201 ttgttttcat taatgattat gctacttgta ccaaaaatct ttgcatcgaa aatgcgagaa
     1261 gttagtctaa atttaactaa ccaaaatgaa gcttttttaa aatctagtga gactatattg
     1321 aatggatttg atgtgttagc gtccttgaat cttttatatg tattgcctaa gaaaattaaa
     1381 gaagcaggaa ttttattaaa gatggttata caaagaaaga caactgtaga aacgttagca
     1441 ggcgctatta gcttctttct caatattttt tttcagatat ctctcgtttt tttaacaggc
     1501 tatcttgcaa taaaaggaat agtgaaaatt ggtactattg aagcaatagg agcactaaca
     1561 ggtgttattt ttacagcgct aggtgaatta ggaggtcaat tatcctctat tattggtacg
     1621 aagcctattt ttttaaaatt gtattcaatt aatccaattg agtcaaataa aatgaatgat
     1681 atcgaaccaa atgaggtgaa tagagatttt ccgttatatg aagcaaaaaa tatttgctat
     1741 aagtatggag ataaagaaat attaaaaaac ttaaattttt gttttcaacg taatgaaaag
     1801 tatttaattt taggtgaaag tggaagcggg aaatctacat tattaaaatt attgaatggc
     1861 tttttgagag attatagtgg agaattgcga ttctgcgggg atgatataaa aaaaacctcc
     1921 tatttaaata tggtttcgaa tgttctatat gtagatcaaa aagcttattt gtttgaaggt
     1981 acgattagag ataatatttt attggaagaa aattatactg atgaagaaat actacagtct
     2041 ttagagcaag ttggtttgag tgtaaaagat tttcctaata acattttaga ttattatgtt
     2101 ggtgatgatg ggagattact atcaggaggg cagaaacaaa aaattacttt agctagaggg
     2161 ctaattagaa ataagagaat agtattaatt gacgagggaa cttctgctat cgataggaga
     2221 acttcgttag cgattgaacg taagatatta gatagagagg atttgactgt cattattgtt
     2281 acccatgctc cgcatccgga acttaaacaa tattttacta agatatatca atttccaaag
     2341 gattttattt aagaatatag gggagggaaa catgagattc tattgtgaag cttatgaggt
     2401 aattactgaa gagaaaaaag tatcattttt tatgtagatg aaaaaccctt aaggtatctg
     2461 ttatttgact atatatttct actagttcta gctaaaaaaa aatatcccaa tcttatgaac
     2521 tgcaccccaa aagttagatt tattctgtct aacttttggg gtgcagttca ttttgcatag
     2581 ttttggcatt catcctagat atccatataa aatgtctgag attgttgaaa tgtctaaaaa
     2641 aatatcagat ctaaacgata aaaaagaatt tcacaaaaag aactgtgagt tgaggtttca
     2701 agatagtgtt cttgat
//
LOCUS       DAVLIK010000105         2623 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLIK010000105 DAVLIK010000000
VERSION     DAVLIK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2623
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.105"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            239..2563
                     /gene="pflB"
                     /locus_tag="VXE87_002116"
     CDS             239..2563
                     /gene="pflB"
                     /locus_tag="VXE87_002116"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0843570.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT          833 a          544 c          511 g          735 t
ORIGIN      
        1 ttcgatttcc attgagtgtt actgcttatt ttcttttatt ataccctttt ttctgaaaaa
       61 aagaaaaaag gactttattt tttcaaaaat ataatacagt ttgaaataaa atatagactg
      121 ttttagaaaa gaaagtgtaa aaatagggaa ttttcacttg ttaaaatcgg ttactatatg
      181 gtatacttgt cttatgaatg taacagatga ctgttactag aaaaaagagg acattaatat
      241 ggttgttaag acagttgttg aagcacaaga tatttttgac aaagcttggg aaggcttcaa
      301 aggcgtagat tggaaagaaa aagcaagtgt atcacgattt gtacaagcta actacacacc
      361 ttatgatgga gacgaaagct tccttgcagg accaacagag cgttcacttc acatcaagaa
      421 aattgtagaa gaaactaaag cacactacga agaaactcgt ttcccaatgg acactcgtcc
      481 aacatctatc gctgatatcc ctgctggatt tatcgacaaa gaaaatgaag ttatcttcgg
      541 tatccaaaac gatgaactct tcaaattgaa cttcatgcca aaaggtggta tccgtatggc
      601 tgaaactact ttgaaagaaa atggatacga accagaccca gctgttcacg aaatcttcac
      661 taaatatgta acaacagtta acgacggtat tttccgtgcc tacacttcaa atattcgtcg
      721 cgctcgtcac gcacacactg taactggtct tccagatgca tactcacgcg gacgtatcat
      781 cggtgtttac gcacgtcttg ctctttacgg tgcagactac ttgatgcaag aaaaagtaaa
      841 tgactggaat gcaatcaaag aaatcgatga agaaacaatc cgtcttcgtg aagaagtaaa
      901 ccttcaatac caagcattgc aacaagttgt tcgcctgggt gacctttacg gggttgatgt
      961 tcgcaaacca gcgatgaacg tgaaagaagc aatccaatgg gttaacattg ctttcatggc
     1021 tgtctgccgt gtgattaacg gtgctgctac atctctaggt cgtgtaccaa tcgtattgga
     1081 catctttgca gaacgtgacc ttgctcgtgg tacatttact gaatcagaaa tccaagaatt
     1141 cgttgatgat ttcgttatga aacttcgtac agttaaattt gctcgtacaa aagcttatga
     1201 ccaattgtac tcaggtgacc caacctttat cacaacttct atggctggta tgggtaacga
     1261 cggtcgtcac cgtgttacta agatggacta ccgtttcttg aacactcttg acaacatcgg
     1321 taactcacca gaaccaaact tgacagttct ttggactgac aaattgccat acaacttccg
     1381 tcgctactgt atgcacatga gccacaaaca ctcttctatc caatacgaag gtgtaacaac
     1441 aatggctaaa gacggatatg gtgaaatgag ctgtatctca tgctgtgtgt ctccacttga
     1501 tccagaaaat gaagaacaac gccacaacat ccagtacttc ggtgctcgtg taaacgttct
     1561 taaagccctt cttactggtt tgaatggtgg ttacgacgat gttcacaaag actacaaagt
     1621 atttgatatc gaaccaatcc gtgacgaagt tcttgaattt gaatcagtta aagcgaactt
     1681 tgaaaaatct cttgactggt tgactgacac ttacgtagat gccttgaaca tcatccacta
     1741 catgactgat aggtacaact acgaagctgt tcaaatggcc ttcttgccaa ctaaacaacg
     1801 tgccaacatg ggattcggta tctgtggatt tgctaacact gttgatacat tgtcagctat
     1861 caaatacgct acagttaaac caatccgtga cgaagatggc tacatctacg attacgaaac
     1921 aatcggtgac tacccacgct ggggtgaaga tgacccacgt tcaaacgaat tggcagaatg
     1981 gttgatcgaa gcttacacaa ctcgtctacg tagccacaaa ctatacaaag acgcagaagc
     2041 tacagtatca cttttgacaa tcacatctaa cgttgcttac tctaaacaaa ctggtaactc
     2101 accagttcac aaaggtgtat acctcaacga agatggttct gtgaacttgt ctaaacttga
     2161 attcttctca ccaggtgcta acccatctaa caaagctaaa ggtggttggt tgcaaaactt
     2221 gaactcactt tctagccttg actttagtta tgcagctgac ggtatctcat tgactacaca
     2281 agtatcacct cgcgctcttg gtaagactcg tgatgaacaa gttgataact tggtaacaat
     2341 ccttgatggt tacttcgaaa acggtggaca acacgttaac ttgaacgtta tggacttgaa
     2401 cgatgtttac gaaaaaatca tgtcaggtga agacgttatc gtacgtatct ctggatactg
     2461 tgtaaatact aaatacctca ctccagaaca aaaaactgaa ttgacacaac gtgtcttcca
     2521 cgaagttctt tcaatggatg acgccttgga tgcattgagc taatcaagtt cttgaataat
     2581 aaaggctctt tgtcaactgt agtgggttga agtcagctaa gct
//
LOCUS       DAVLIK010000106         2561 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLIK010000106 DAVLIK010000000
VERSION     DAVLIK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2561
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.106"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            389..1393
                     /locus_tag="VXE87_002117"
     CDS             389..1393
                     /locus_tag="VXE87_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEV0843571.1"
                     /translation="MNASFRGSASFIRDNVLVTAAHVVYDRDSRTEADSVYVIPAATP
                     NENPVGKIKVKEVRYLKEFQNTASNELTTYDLAVLILEEPIGAQLGTLGLPNNLGNLS
                     GTGATITGYPAVNSAKQMYTDSKDIVKDTGDFLMYQIDTLGGASGAGVYDSSFRLIGV
                     HVSGSSAGQMNSAVKLNEKALSFIYSVIQGHSIDGWKLISGTWYYYKNSTKQTGWQKI
                     NDTWYYLDASGKMRTDWEKVNGKWYYFESSGSMATGWKYVRGNWYYLDNKNGDMKTGW
                     YKDGSTWYYLDPTNGNMKKGWIKVGGNWYYLNSSGAMVTGSQTIDGKVYNFASSGEWI
                     "
     gene            1412..2392
                     /locus_tag="VXE87_002118"
     CDS             1412..2392
                     /locus_tag="VXE87_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0843572.1"
                     /translation="MKLLKKTMQVGLTAFFFGLLATNTVFADTTGGQFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGNKGEMVVGWQYLEIPGTGYRDNLLDNQPVNEIGLQHKW
                     YYFGQDGSLQEYVGWKELDAKDSLNVGKEYGEPFEGPEVLKYANYYFDKDHSLKTGWF
                     YDQSNWYYLAKTGYLGKDYLGGERRAGWIYDGSSWYYLDTTTAAMQTGWQYLGNNWYY
                     LRSSGAMATGWMKDASTWYYLDGQNGDMKTGWAYVGNSWYYLRSSGAMSTGWMKDGST
                     WYYLNASNGDMKTGWFQVNGKWYYAYGSGALAVNTTVGGYYVNYNGEWVK"
BASE COUNT          866 a          326 c          556 g          813 t
ORIGIN      
        1 gaagatgcta tattttctca attaatatat tgaaaagtat agaatggtat gctataatca
       61 cattaggagg ataaaaataa tgaagaaaaa tttttataaa aaattgggta tttcaattat
      121 tgcgagtact ttattggcta gccagttgtc gacagtatct gctttgactg ttatttctag
      181 tacaggtgaa gaatatgagg taagtgaaac attacaagag agtccaggaa ctaataattt
      241 ttcacttccc gatatttcac cgacttatgg taaatattat acaaatcagt cagaagtcat
      301 tattggcaac aatgatttag ttaagattgg gaatacttta cagtatcctt attctacatc
      361 agcttacgta aaagcagaat ttaatagtat gaatgctagt tttagaggca gtgctagttt
      421 cataagagat aatgttttgg ttacagcagc tcatgttgtt tatgatcgtg attctagaac
      481 agaggcggat tctgtatatg ttatccctgc ggctactccg aacgaaaatc ctgtaggaaa
      541 aataaaggta aaagaagttc gttatctaaa agaatttcaa aacacagctt caaatgagct
      601 tactacgtat gatttagcag ttttgatttt ggaagaacca attggcgctc aattaggtac
      661 actaggtctt ccgaataatc tagggaatct ttcaggtaca ggggctacta ttactggata
      721 tcctgctgta aatagtgcta agcaaatgta tactgactct aaggatattg taaaagatac
      781 tggagatttt ctaatgtatc aaatagatac tctaggaggt gctagtggag ctggcgtata
      841 tgacagcagt tttagattga ttggtgttca tgtgtctggt agttctgctg gacagatgaa
      901 ttctgctgtt aagttaaatg aaaaggcttt atcatttatc tactctgtta ttcaaggaca
      961 ttctattgat ggttggaaat tgattagtgg tacatggtac tattataaga acagtactaa
     1021 acaaacaggt tggcagaaaa taaatgatac ttggtactat ctagatgctt caggtaagat
     1081 gcgtacagat tgggaaaaag taaatggaaa atggtattac tttgaatcat ctggttcgat
     1141 ggcaacaggt tggaaatatg tacgaggcaa ctggtattac ttagataata aaaatggtga
     1201 tatgaagact ggttggtata aagatggttc aacatggtac tatctagatc ctactaatgg
     1261 aaacatgaaa aaaggttgga taaaagtagg aggaaactgg tattatctaa attcaagtgg
     1321 agcaatggtt acaggtagcc aaactatcga tggtaaagtt tataatttcg cttcatctgg
     1381 tgagtggatc taatattgga ggggtatata aatgaaactt ttgaaaaaaa ctatgcaagt
     1441 tggactaaca gcatttttct ttggtttgtt agctacaaat acagtatttg cagataccac
     1501 aggtggccaa tttgttgata aggacaatag aaaatattat gtaaaagatg atcataaagc
     1561 aatctattgg cataaaatag acggaaaaac ttactatttt ggtaataaag gagaaatggt
     1621 agttggatgg caatacttag aaattcctgg aacaggttat cgtgataatt tattagataa
     1681 ccaaccagtt aatgaaatag gccttcaaca caagtggtac tattttggac aagatggaag
     1741 tctccaagaa tatgttggtt ggaaggaatt agatgctaag gattcattaa atgttggcaa
     1801 agagtatggt gaaccatttg aaggtcctga agttcttaaa tatgcaaatt attactttga
     1861 taaagatcat tctttaaaga caggttggtt ttatgatcaa tccaactggt actacttagc
     1921 aaaaacaggt tatttaggaa aagactatct tggtggtgaa agacgtgcag gttggatata
     1981 tgacggttca agctggtatt atctagatac aacaactgct gcaatgcaaa caggatggca
     2041 atatctaggt aataactggt attatctccg ttcatcaggt gctatggcaa ctggttggat
     2101 gaaagatgct tcaacttggt attatctaga tggtcaaaat ggtgatatga agacaggttg
     2161 ggcttatgtt ggcaacagtt ggtactacct tcgttcatca ggtgcaatgt ctactggttg
     2221 gatgaaagat ggttcaactt ggtactacct aaatgcaagt aatggagata tgaagacagg
     2281 ctggttccaa gtcaatggta aatggtacta tgcctatggt tcaggtgctt tagctgttaa
     2341 taccacagta ggtggttatt acgtaaacta caacggtgaa tgggttaagt aatgaaggct
     2401 aatgttaaac tatagttgat acttaacata gtaaaagaga gaatcagagt gtgattctct
     2461 cttttgtaat ttaaaatgat tttaagaaag tttttatatg tgtttgaaaa attgtataat
     2521 ctatgtgatg gattaaattt ctacaagttt tatagagtca a
//
LOCUS       DAVLIK010000107         2541 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLIK010000107 DAVLIK010000000
VERSION     DAVLIK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.107"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            66..768
                     /locus_tag="VXE87_002119"
                     /pseudo
     CDS             66..768
                     /locus_tag="VXE87_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(915..1760)
                     /locus_tag="VXE87_002120"
     CDS             complement(915..1760)
                     /locus_tag="VXE87_002120"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0843573.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            2016..>2541
                     /locus_tag="VXE87_002121"
     CDS             2016..>2541
                     /locus_tag="VXE87_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843574.1"
                     /translation="MLYVGIDVAKNKHDVTALNVQGKTVLKPLTFSNNKAGFELLDLS
                     FRQLNQDCLIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLD
                     IIFPELDKIVGKHSEYTYQLLTRYPNPQKRLEARFDKLIEIKRLTASKIQDILSIAPR
                     SIGTTSPAREFEIIE"
BASE COUNT          842 a          525 c          494 g          680 t
ORIGIN      
        1 tgaggttgca gatagagctg acgtggtttg aagagatttt cgaagagtat aaaaaggtgc
       61 taggcatgtt gatttttcct ttgttaaatg atttgtcaag aaaaatcatc catattgaca
      121 tggatgcctt ttttgctgca gtggaaatca gggataatcc taaactcaga ggaaaacctg
      181 tcattattgg aagcgaccct cggcaaacag gtggacgggg agtcgtttct acctgtagtt
      241 atgaggcaag agcttttggt gtccattctg ccatgagttc caaggaagct tatgaacgtt
      301 gtccccaggc tgtctttatc tcagggaatt atgagaaata caagtctgtg ggactccaga
      361 ttcgagctat ttttaagcgc tatacagatt ggtagactag gctatgatct gtatcgaaag
      421 gctcgtggca ttcacaactc tccagtcaaa tccaatcgca tccgtaaatc aatcggcaag
      481 gagaaaacct acgggaagat tctccgtgct gaggaagata tcaaaaaaga gctgactctt
      541 ctatcagaaa aagtcgctct caatctacat caacaagaaa aagctggaaa aattgtcatt
      601 ttgaaaatcc gctacgagga cttttcaact cttaccaaac gaaaaagtct tgctcaaaaa
      661 acacaagatg ctagtcagat aagccaaata gccctgcaac tctatgaaga attaagcgag
      721 aaagaaagag gtgtccgcct attggggatt accctgactg gattttaaag ctcaatgaaa
      781 atcaaagagc aaactaggaa gctagccgca ggctgctcaa aacactgttt tgaggttgca
      841 gataaagctg acgcggtttg aagagatttt ctaagagtat aaaaccttga agagttgccc
      901 cttcaaggtt tttcttatac aaataaacgg acaaaactgt aaagtagcaa aacactacca
      961 agcacgatac ggtatttacc aaaaagggtg aagtcgtgtt ttttcacata gctggtcaag
     1021 aagcgaatag ccaccatgct gaccgcaaaa gctactccca tcgcgaccaa gagcaaaaac
     1081 aattgcccaa agctcaagag ttctccggct ttcacaaatt tgaaaatctt taaggcacta
     1141 gctccaaaca taacaggaat cccaagatag aaggtaaatt ctgtcacaac tgaacgactg
     1201 gttccattta acaaaccacc gacaatcgtt gcacctgaac ggctagtccc tggtaaaaga
     1261 gcaagaactt ggaagagtcc gatatagaaa gcggtcgtat aaggaagctt gtccaactct
     1321 gttacacttg gctcgatagc acgcgcttta ttgcgctttt ccaaatagat gaaggcaacc
     1381 ccgtagataa tcaacatgag agcaactgaa accatgttat ggaagtgggt atcaaaccaa
     1441 tcatcaaatt taaagacacc aagtaaaggc aaagtggcaa tcaagacctt caaccatagt
     1501 ctccaagtct tacgaacttc ctgtttgtcc ttagtcggtt taaaaggatt gagcttgtta
     1561 aaataaatca ccataactgc taaaatagca ccaagctgaa ttacgacatt aaacatggac
     1621 ataaaggctt cattttgatt ttggtattgg ataaactcct ctgctaaaat caagtgacct
     1681 gtactggaaa tcggcaacca ttccgtaatt ccttcaacaa tcccgaagaa gatagatttt
     1741 aaaatttcaa taagatacat agatttctcc ttatattata tttaacgcag ttagctactg
     1801 ccaaagccca agtggtatac ttggaataag ccactgtgga ttagttcatt tcctccaatc
     1861 gcttgacgat ttccgaaagg gtctaaccac agctttttgt ttcaattggt aatgagtttg
     1921 ataacgcata gacgttttat ctcgtctaag gtaacaaggc aaaaagttcg tggataacca
     1981 agtagacttg aaatactata tctggaggta ctcccatgct ttatgtgggc attgatgtcg
     2041 ctaaaaataa acacgatgtt acagccttga atgttcaagg aaaaactgtt cttaaaccac
     2101 tcactttttc aaataataaa gctggttttg aactcttaga tctgtctttt cgacagctca
     2161 accaagactg tctcatcgct cttaaacttc tttctgaccc caatcgtgaa caatttcaac
     2221 acgataatcg gcaagtagaa ctaaaaatac tggctagaca tattcatcgt ctcaagaaaa
     2281 aacagtctga ttggaaagta caatacactc gttgtcttga tatcatcttt cctgagttgg
     2341 ataaaatcgt tggaaagcat tcagaatata cctaccaact cttgacacgc taccctaatc
     2401 ctcagaaaag gcttgaggca agatttgata agctgataga aattaagcga ttgaccgctt
     2461 ctaaaattca ggatatcctc tcaatcgcac ctcgttctat cggaacaaca tctcctgctc
     2521 gtgaattcga aatcatcgaa a
//
LOCUS       DAVLIK010000108         2533 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLIK010000108 DAVLIK010000000
VERSION     DAVLIK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2533
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.108"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..629
                     /locus_tag="VXE87_002122"
     CDS             <1..629
                     /locus_tag="VXE87_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843575.1"
                     /translation="RVFRELDSIWEIFISLKYFFESENSLDVDNISEFCGIAYGGIEI
                     PLVAHLFKEKNEISFLFQNSHYSTQEVEVKRFRDSRRNDSKSILLMDDNILTGRAMKN
                     AAQKLSYRKYSVQFFHVRRLGLNRLSQVIQENSMNELQRYLTGIYKGGIFPAPYSKIK
                     FGTNIAKQYLDELQIFTLSGDEILRLLYKNGLFSEESEVKVVRGNLYE"
     gene            626..1261
                     /locus_tag="VXE87_002123"
     CDS             626..1261
                     /locus_tag="VXE87_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase"
                     /protein_id="HEV0843576.1"
                     /translation="MTFPISEWKRNEEFDFFNKMDVPYLSMSSRIEVTQAINFHKKHS
                     ISLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTSEDKLNFSSFTMGD
                     NLIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVSTPMNLSKIDTVPRI
                     TWGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKINEYFQKK"
     gene            1329..>2533
                     /locus_tag="VXE87_002124"
     CDS             1329..>2533
                     /locus_tag="VXE87_002124"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0843577.1"
                     /translation="MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYV
                     SGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIV
                     QELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAIL
                     DPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTK
                     RYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNIT
                     DFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSN
                     NWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRT
                     LKFIEKYFES"
BASE COUNT          912 a          330 c          467 g          824 t
ORIGIN      
        1 ctcgtgtttt tagggaatta gattctatct gggaaatttt tatttcttta aagtatttct
       61 ttgaaagtga aaattcattg gatgtagata atattagtga attttgtggg atagcttatg
      121 gcgggataga aattcccttg gttgcgcacc tatttaaaga aaaaaatgaa atatcatttt
      181 tatttcaaaa tagccactac agtactcaag aagttgaagt aaaaaggttc agggacagtc
      241 ggagaaatga ttcgaaaagt atcttattaa tggatgataa tattttgaca ggaagggcta
      301 tgaaaaatgc tgctcagaaa ttatcatacc gaaaatattc agtccaattc tttcatgtca
      361 ggaggcttgg cctaaataga ttatcacaag ttattcaaga aaattcaatg aatgaattgc
      421 agaggtattt aacaggaata tataaaggag ggatttttcc tgcaccgtat tcaaaaatta
      481 aattcggtac taatattgct aaacaatatt tagatgaatt acaaattttt actctatctg
      541 gagatgaaat cttaagacta ctttataaga atggcttgtt ctcagaagag agtgaagtga
      601 aagtggtaag ggggaattta tacgaatgac atttcctata tcagagtgga aaaggaatga
      661 agaatttgac tttttcaata aaatggatgt tccttattta tctatgagtt cacgaataga
      721 agtaacgcag gctatcaatt ttcataaaaa acattcgata tcactttatg ccataatatc
      781 gtggtgtgtt atgagtgcaa taaattctat tccagaatta ctaatggata ccgacggaaa
      841 gattgtctgg caatacaatc aaagaggttg ttctttcact acccttacat cggaagataa
      901 gcttaatttt tcttcattta cgatgggaga taatttaatt gaatttgttt ctgcgttcaa
      961 cataaataaa cagaaggcag aagaagggca aaaaccaaat attgacaaga ataacattgc
     1021 ttatctttct tgtgttccat ggattgattt tttacatgta agcactccta tgaatctttc
     1081 aaaaattgat acagttcctc gaataacgtg gggaaaagtt attcaagaga accaaagata
     1141 tttttgtaca gtgaatttac aaattaatca tggaatggga gatggattac acgtatctaa
     1201 tttttttgtg ttattgcaaa ggtttgtaaa taaaataaat gaatattttc aaaaaaagta
     1261 atgattgaaa agatattgca tttaaataat gttataataa aaataaagaa tttaaggaga
     1321 aatacaatat gtcaattttt attggaggag catggccata tgcaaacggt tcgttacata
     1381 ttggtcacgc ggcagcgctt ttaccggggg atattcttgc aagatactat cgtcagaagg
     1441 gagaggaagt tttatatgtt tctggaagtg attgtaatgg aacccctatt tctatcagag
     1501 ctaaaaaaga aaataagtct gtgaaagaaa ttgctgattt ttatcataag gaatttaaag
     1561 aaacttttga aaaattaggt tttacatatg acttgtactc gcgaacagat tctccactac
     1621 atcatgagat agtacaagaa ttatttttgc aattatacga gaagaaattt ttgtatacaa
     1681 aaaaaattaa acaactctat tgtacatttg ataatcaatt cttacctgat aggttcgttg
     1741 aaggaaaatg cccgaattgt ggaacccatt caagaggaga tcaatgtgat aattgctcag
     1801 caattttaga tcctatagat ttagttgata aaagatgttc tatttgttcc aatgaaccag
     1861 aagttcgtga gacagaacac ttttattatg tttttagtga gtttcaaaat ttgttagaga
     1921 cttacttaaa tgatgctgaa gaaacagtga gatggcgaaa aaatgcaata aatctaacta
     1981 aaaggtattt acgggaaggt ttacctgatc gagctgttac tcgtgatcta ccaaatggga
     2041 ttccagttcc cattgatggt tttagagata aaaaaatata tgtctggttt gaagcggtag
     2101 caggttacta cacagcaagt gttgattggg cgcaaaaact tcaaaataat attactgatt
     2161 tttggaacaa tcggacaaag tcatattatg ttcatggaaa agataacatc ccatttcata
     2221 ctattatttg gccggcaata ctctcaggtt tagaaataga gcctcttcca gagtatatta
     2281 tttctagtga atatttaacg ttagaaaaca aaaaaatatc aacaagtaat aattgggcta
     2341 tatggcttaa cgatatcata aaaaaatatg atgctgattc aatccgatac ttcctaacaa
     2401 taaatgctcc tgagatgaaa gatgcaaatt tttcttggag agaatttatt tatagtcata
     2461 actcagaatt attaggatcg tacggtaatt ttatcaatag gactctaaag tttattgaaa
     2521 agtattttga atc
//
LOCUS       DAVLIK010000109         2218 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLIK010000109 DAVLIK010000000
VERSION     DAVLIK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2218
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.109"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            72..2099
                     /locus_tag="VXE87_002125"
     CDS             72..2099
                     /locus_tag="VXE87_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0843578.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQLLSLYPTLKNFAKYD
                     CIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLFYIHLDYRILALNTAE
                     NLESGNSSIVPVKDGKQILTNQLFDGECDDIYLLTVHSPMNKALEILSEKYKQISGKN
                     IKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQEITSFRQTKSINQNI
                     SKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQ
                     EFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRERLAQSRMNLAVLPQV
                     LTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSPLFDGLNVSAQFEFAT
                     ATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILLTSLGGFLPSKYVMQN
                     RMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELIESVKHRYG"
BASE COUNT          792 a          270 c          366 g          790 t
ORIGIN      
        1 aagcatttca aattaaagag cgtaaagaga tctcaaatat actaaaagat ctcttaaact
       61 agaggttaat tatggttaca ataaaagata ttgcaagagt gtctggagtc tcacatggga
      121 cagtttcaaa cgttttaaat aaaaaaggta atgtctcagc agctaaaata aagttagtag
      181 aagagactgc gaaaaaattg ggttataata tgaattctca agctcagttt cttcgaaaag
      241 gcgcttctag taaatgtttt ttcttgttat ttaataatgc acgcaaaaag tatgctgagt
      301 attttgcaga aattgatcag ttatctttag atgtagaata tgtttactta cataaattct
      361 cagagattaa aaataagata tctgcaattt taagtgaaaa tcctcaattt atagtttgct
      421 taggtttttc tccaaaaaga ttcgttgata ttgaagataa tattccgatt tttgaagtag
      481 atacatatca atctaataaa actttatctt cctttgatag tgataaaata tttgagattg
      541 tacttgagtt ggttcggact gaaaagctat ctaatttata ttttatttca cttactaatg
      601 aaaaagaaca ttctttattt gaatatttga ctcaaaaaat aaaaaactca actcatatac
      661 aagtgcaaga acgtttacaa ttgttgtctc tatatcctac tctaaaaaac tttgcaaagt
      721 atgattgtat atttgttgat gatgaagatt tgatgcacac gctattagac ttatttgatt
      781 ggtttactat aattgataga ccaaaaatat gtttgatagg ttcacgtgtt tggttcgaaa
      841 aaagaaatct tttttatata catttagatt atagaatatt ggcactcaat actgccgaaa
      901 atttagaaag tggaaatagt tcaattgtac cagttaaaga tggcaaacaa attttaacta
      961 atcaattatt tgatggagaa tgtgatgata tttatttact tactgtccat tcaccaatga
     1021 ataaagcctt agaaatttta tcagaaaagt ataaacaaat ttctgggaaa aatattaaaa
     1081 ttatcgagaa aagatatgat gaacttttgg agatgattga gtctggcgat gtttcatcca
     1141 gttttgatat gattagaatg gatatggctt ggcttccaac atttgggaaa aagtattttc
     1201 aagagattac aagctttaga caaacaaaaa gtattaatca aaatatttct aagtcggtgt
     1261 ctcgagagta tatgtatatt gatcagaagc aatatacttt tccattggat gttagtagtc
     1321 agattttagt atatagaaaa gacttatttg aagattcatt tttacaaaga cgatactttg
     1381 aaaaaacaaa aagaaaatta actgtaccaa aaagttatca agagtttgat gagttaagtg
     1441 aattttttac attaacagaa aatccatttt cacctacact ttatggccat agtttagctt
     1501 taagttcttc agtgagagca gcatgtgaat ttattcctcg gtttcgtgag agattagcac
     1561 aatctagaat gaatcttgct gtacttcctc aggttttaac tgagtatgag aaaagttatc
     1621 agtttaccga aaaatcattt aattcttcgt ggaacgattt cgttacgaac ttaaacagtg
     1681 gtaaaacttc aatggaaata attttttcaa attatactag tccattattt gatggtctca
     1741 atgtttctgc tcagtttgag tttgcaactg ccactatacc tggtaatact cctgtgatag
     1801 gtggtggctc aattggaatt tctaaatatt caaatagagt ggaagaatgt ctaaacttta
     1861 ttaattggtt atattctgaa gagatttcta ttttactaac atctctgggt ggttttttac
     1921 catcaaagta tgtcatgcaa aataggatgt tacaatttca atacccatgg ttatctagtt
     1981 tagaagatac atttagtatt gggagtagaa caaaatggta cggctttaat actgatttta
     2041 gatttgagca gatgttaggg caagagttaa tagaaagtgt gaagcataga tatggataaa
     2101 ttaatactaa atttttatta ctagtttatt tattattgtt taaaattaaa gattcaagta
     2161 aacaccaatt atatttaaaa ttattatttt gacatttttc tattgcaaag ttatttta
//
LOCUS       DAVLIK010000110         2184 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLIK010000110 DAVLIK010000000
VERSION     DAVLIK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2184
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.110"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            43..915
                     /locus_tag="VXE87_002126"
     CDS             43..915
                     /locus_tag="VXE87_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0843579.1"
                     /translation="MIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQT
                     MLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKD
                     GFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLI
                     VSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPI
                     ACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSP
                     YLIYLLIKMNRRNI"
     gene            915..1709
                     /locus_tag="VXE87_002127"
     CDS             915..1709
                     /locus_tag="VXE87_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843580.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHINS"
BASE COUNT          810 a          332 c          360 g          682 t
ORIGIN      
        1 ttcattttac ttatcggaga tgaaagttat tctttttcaa ctttgattaa agtcttaaat
       61 agtgaaactg ttcctggagc tagtttttcg attatggaaa ttagattacc aaaattatta
      121 gcaggaatta tagctggctg gtcttttgga ttggcaggat ttatctttca aactatgtta
      181 agaaatcctc ttgcaagtcc tgatataatc ggtgtcacaa gttcttcatc tattgcagcg
      241 gtcttttgca tattggtatt aaaaacaaat agtttaacta ctggaattat ttcaataact
      301 tgtggactaa catcatcttt aatattattt ttactagcta aaaaagatgg tttttcagca
      361 gcaagactga taatattagg tattggtttt caagctgtca caagagcagg cacctcattt
      421 ttattgttga aagtagcaag atatgaatta caagaagtta tgagatggct cagtggctct
      481 ttatctttta caaagttaga tgacatacct cttgttctaa tagtaagtat tattgctact
      541 atattagttt tattttttaa taaaagacta gaaattattg aacttggtga agaaatagca
      601 atcggacttg gagcaaatcc cgagctttca aggcttgttt taattttttg cgctgtatct
      661 ttaactgctt tttctacttc aattacagga ccaatagctt gtatatcttt tttagctggt
      721 cccatagcct taaatattgg caagaaaaga agcccaatat tagctggatt ggttggaatt
      781 ttactagttt tgttatcaga catattctct caaaatattt taccagctag atatccagta
      841 ggtgttgtaa ctggcttgtt aggttcacca tacttaatat acttactaat aaaaatgaac
      901 aggagaaata tataatgaaa ggtctgtggt caaataatct tacctgcggt tatgatgaaa
      961 aaataatctt ggaaaatata aatataaaaa tacctgaaga aaaaatatca gttattattg
     1021 ggtcaaatgg ttgtgggaaa tcaacactca ttaaaacctt gtctcgactt ataaagccat
     1081 tagagggaga agtattgctt gataataaat caattaattc ttataaagaa aaagatttag
     1141 caaaacacat agctatatta cctcaatctc caataatccc tgaatcaata acagtagctg
     1201 atcttgtaag ccgtggtcgt ttcccctaca gaaagccttt taagagtctt ggaaaagatg
     1261 accttgaaat aataaacaga tcaatggtta aggccaatgt tgaagatcta gcaaataacc
     1321 tagttgaaga actttctggg ggtcaaaggc aaagagtatg gatagctcta gccctagccc
     1381 aagatacaag tatcctactt ttagatgagc caactactta cttggatatc tcatatcaaa
     1441 tagaactatt agacctcttg actgatctaa accaaaaata taagacaacc atttgcatga
     1501 ttttgcacga tataaatcta acagcaagat acgctgatta cctatttgca attaaagaag
     1561 gtaaacttgt tgcagaggga aagcctgaag atatactaaa tgataaacta gttaaagata
     1621 tctttaatct tgaagcaaaa attatacgtg accctatttc caattcgcct ctaatgattc
     1681 ctattggcaa gcaccatatt aactcttaat aattgaatat tggaattcat ttaaaagtcg
     1741 caaattttga actgaccctc aaaagttagg ccaaaaaact aactaaagga ggtcagtttt
     1801 ttaatggcaa atacagcaca gaatttaaga taaaattagt aaaagaatat catgaatgaa
     1861 aaataggata tagagaataa cagcaatatt aaaaagatca ggactgataa taaacaaaaa
     1921 gaaagtacaa cgactagttc aaaagctaaa acttcaagta aaaagttatt caagaaaatc
     1981 tagaaaatac tcatcctaca aaggacaggt aggaaaaata tcagacaaca aaataaaaag
     2041 aaatatttat taccgaaaaa aaggggaaat cgagttaagt accaacaggc tcatctattc
     2101 caaaaagata tttactcgat ggaaaaactc ctagaattag tgctacaaat attgacaatg
     2161 gtatcttagg ttactacgaa gata
//
LOCUS       DAVLIK010000111         2143 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLIK010000111 DAVLIK010000000
VERSION     DAVLIK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2143
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.111"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            52..1077
                     /locus_tag="VXE87_002128"
     CDS             52..1077
                     /locus_tag="VXE87_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0843581.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1067..2074
                     /locus_tag="VXE87_002129"
     CDS             1067..2074
                     /locus_tag="VXE87_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0843582.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
BASE COUNT          761 a          301 c          375 g          706 t
ORIGIN      
        1 atgataatta ttatcgatac aatagacttg aaatatgttt aaggagtttt tatgaaaaac
       61 aaattttttc taatagctat tttagctatg tgtatagttt ttagcgcttg ttcttctaat
      121 tctgttaaaa atgaagaaaa tacttctaaa gagcatgcgc ctgataaaat agttttagat
      181 catgctttcg gtcaaactat attagataaa aaacctgaaa gagttgcaac tattgcttgg
      241 ggaaatcatg atgtagcatt agctttagga atagttcctg ttggattttc aaaagcaaat
      301 tacggtgtaa gtgctgataa aggagtttta ccatggacag aagaaaaaat caaagaacta
      361 aatggtaaag ctaacctatt tgacgatttg gatggactta actttgaagc aatatcaaat
      421 tctaaaccag atgttatctt agcaggttat tctggtataa ctaaagaaga ttatgacact
      481 ctatcaaaaa ttgctcctgt agcagcatac aaatctaaac cttggcaaac tttatggaga
      541 gatatgatta aaattgattc aaaagcctta ggtatggaaa aagaaggtga tgagttaatc
      601 aaaaatactg aagctcgtat atccaaagaa ttagaaaaac atccagaaat caaaggaaaa
      661 atcaaaggaa aaaaagtatt atttactatg attaatgctg cagatacatc aaaattctgg
      721 atttatacta gcaaagatcc aagagcaaat tatttaacag atttaggtct agttttccct
      781 gaatcattaa aagaatttga gagtgaagat agttttgcaa aggaaatttc tgcagaagaa
      841 gcaaataaga taaatgatgc tgatgtaatc ataacttatg gtgatgataa aactcttgaa
      901 gctttacaaa aagatcctct tttaggtaaa ataaatgcaa ttaaaaatgg tgccgttgct
      961 gtaattccag ataatacacc gttagcagcc tcatgcactc caacaccact ttcaataaac
     1021 tatactattg aagaatacct aaatctttta ggaaatgcat gcaaaaatgc gaaataaaaa
     1081 acaaataaac ctaggcataa tttttgtaat ctgcctaggt cttcttatta caatattttt
     1141 gtcattaaag cttggaacaa aagaaattaa tatcagagat tttttagcag cttttggaat
     1201 gggcaataca aatgatgatt ttattaaatc aattatatat aaaagaatac ctagaactat
     1261 ttttgcaatt ttagcaggtt ctagtcttgc cataagcggt gtattgatgc aatcagttac
     1321 tagaaaccca atagctgatc caggtatact cggtataaac acaggagcaa gtcttagtgt
     1381 agtaattggt ctttcttttt taggaatttc atcaagcata agccatataa gttttgcaat
     1441 cattggtggc ttagtaagtg caatttttgt atacgcgatt gctgtaagcg gaaaagcagg
     1501 ccttacccct ataaaacttg ccttatcagg aacttgtgtt agtatggctt taagcagttt
     1561 tgtaagtttt ttaattttac cgaataataa cgtcttagac aaatttagat tttggcaaat
     1621 aggtagcctt ggagcagcta cattatcttc tatatctaca ctactacctt ttataatttt
     1681 aggtcacttg atagctatat ttatttcatc agatttaaac gctttagcta tgggtgatga
     1741 aatggctgtt ggtcttggag ttaatgttaa taggataaga tcacttgcaa taattgcaag
     1801 tgtgctttta tgttcaagta ttactgcaat tggtggacct attggcttcg taggtcttat
     1861 agttcctcac ttttgtggct tatttataag caaagatata cgcacaatga ccatttcttc
     1921 atcttttata ggtgcagagc tcttgcttat atgtgatata atcggccgta tgttaggtaa
     1981 accaggtgaa attgaagtag ggataattac tgcaataatc gggggtccag tacttattta
     2041 tgtaactatg aaaaatagag gggttaataa ctaatgcaaa atttaattat aggtattcaa
     2101 aaaagaaaaa atagaataac actattttcc tcactatttt tat
//
LOCUS       DAVLIK010000112         2108 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLIK010000112 DAVLIK010000000
VERSION     DAVLIK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2108
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.112"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            24..1793
                     /locus_tag="VXE87_002130"
     CDS             24..1793
                     /locus_tag="VXE87_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HEV0843583.1"
                     /translation="MANNRQIETLGVSYLTTFINRHSLLQTYFGSNDKTPVWDGEIHV
                     LKTSSEKRSEIFGKVPVQIKATRQQKNKLKSFSLDISDLELYSKSGGVVLFVVWLSED
                     GDLRNIYYKSLPPLSIKKLIKKSNLKNKTTSSKKLSVQIHELDEQKLYPMLVDFITNS
                     RKQYSFINVDGISVEDISDDSNLKFYYYGQEKGEIFNYQEENDLFIYYKNPLTGIEVP
                     LENTIKVVETYEETDLIITIGNTIFQNVKRHRFPDGSVQLHFGEGFKMSFDVKKKQFT
                     FNYTRPNMLSKAIKCTQAFQELGKFGYCKLNGNIIELDEQSILDITSRDLETEIEELV
                     QISNFMENMRIQKEVDLTYFDKQSLRNLNILNLGLILKNKVALNYNESKLLHLRIANI
                     HIITLYDFETDNIGTMIDIFTETPWCRRGEGEDSSYISIFEVLEPNDWLKIDNCDFDS
                     VISSYQRLVDNGLKFEDANNTIIKIVIAADKAEDVSRSELLLNWAQCLSDWNLKYSKN
                     CEMAIINDLQIKSRVRKLNSKEMEILSNILVNSNDNYELCFGSSVLLKSKPQADLFWN
                     KLDNETKESYKEFPIYTLYMKLL"
     gene            1822..2106
                     /locus_tag="VXE87_002131"
     CDS             1822..2106
                     /locus_tag="VXE87_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843584.1"
                     /translation="MEIKKVMYYNTVPQFLKPKLNYFARDFLNDYSVQIEDIEAGSNF
                     EVDVEYEGNLEVYFVKFMFRKKGGGMFSGNSENELDIYCNNELSATVILE"
BASE COUNT          803 a          259 c          366 g          680 t
ORIGIN      
        1 gagttattta tcgaggttag aatttggcaa ataatagaca aattgagaca ttaggtgttt
       61 cctatctgac aacattcata aatagacata gtttacttca gacttatttt ggtagtaatg
      121 ataaaactcc agtctgggat ggtgagattc atgttcttaa aacttctagt gagaaaagaa
      181 gtgaaatatt tggtaaagtg cctgttcaaa ttaaagctac aaggcaacag aagaataaat
      241 tgaaatcctt ctcgttggac ataagtgatt tagaattata ttcaaaaagt ggtggtgtag
      301 ttttattcgt agtttggtta agcgaggatg gtgatttaag aaatatctac tataaatcat
      361 tacctcctct ttctataaag aagctgatta aaaaaagtaa tttaaaaaat aaaacaacaa
      421 gcagtaagaa actttctgta cagattcatg aattagacga acaaaaactg taccctatgc
      481 tagtcgattt tataacaaat agtcgtaagc aatatagctt cataaatgtt gatggtattt
      541 cagttgaaga tatctctgat gatagtaacc ttaaattcta ttattatggt caagaaaaag
      601 gagagatctt taactatcag gaagaaaatg atctcttcat ttattataaa aatcctttaa
      661 ctggtattga agtaccactt gaaaatacaa taaaggttgt cgaaacttac gaggaaacag
      721 atctaattat tacaataggg aatactattt ttcaaaatgt aaaaaggcat agattccctg
      781 atgggagtgt acaactccat tttggtgaag gttttaaaat gtcatttgat gttaagaaga
      841 aacaattcac atttaactac acaagaccta atatgttatc aaaagccata aagtgcactc
      901 aggcatttca agaactagga aaattcggat attgcaagct caatggtaat ataatagaac
      961 tagatgaaca gtcaatattg gatattactt cacgtgattt agagactgag atagaggaat
     1021 tggtacagat ttcaaacttc atggaaaata tgaggataca aaaagaggtt gatctaactt
     1081 actttgataa acaatctcta agaaatctaa atattctcaa tttaggcctt attctaaaga
     1141 ataaagttgc cttaaattat aatgaatcaa aattacttca cctaagaatt gctaatatcc
     1201 acattattac cttatatgac tttgagacag ataatattgg aactatgata gacattttta
     1261 ctgaaactcc ttggtgtagg agaggtgaag gtgaagattc gtcctacatt tcaatctttg
     1321 aagttttaga accaaatgac tggctaaaaa tagataattg tgattttgat tcggttatct
     1381 cctcttacca aagattagtt gataatggct tgaaatttga agatgctaac aacactatta
     1441 taaaaatagt tattgctgct gataaggcag aagatgtttc cagaagtgag ttattgctta
     1501 attgggcaca atgtctttct gactggaact taaaatactc aaaaaattgt gagatggcta
     1561 taataaatga ccttcaaata aaatctagag ttcgtaaatt aaacagcaaa gaaatggaga
     1621 ttctgagtaa cattttagta aatagtaatg ataactatga actttgtttc ggttcatcag
     1681 tgttattaaa atcgaaacca caagctgatt tgttctggaa taaacttgat aatgagacaa
     1741 aagaaagcta taaagaattt cctatttata ctttgtatat gaaattattg taaaattaaa
     1801 agaggctgga agaaaaaata tatggaaata aagaaagtaa tgtattacaa tacagtgcca
     1861 caatttttaa aacctaaatt aaattatttt gcaagagatt ttctaaatga ttattctgtt
     1921 cagatagaag acattgaagc aggttctaat tttgaagttg atgtagagta tgaaggcaat
     1981 ttagaagttt attttgtcaa atttatgttt agaaaaaaag gtggtggaat gtttagtggt
     2041 aattctgaaa atgaattaga tatttactgc aataacgaac tctctgcaac tgtaattttg
     2101 gaataata
//
LOCUS       DAVLIK010000113         2088 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLIK010000113 DAVLIK010000000
VERSION     DAVLIK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.113"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            122..862
                     /locus_tag="VXE87_002132"
     CDS             122..862
                     /locus_tag="VXE87_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0843585.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            865..>2088
                     /locus_tag="VXE87_002133"
     CDS             865..>2088
                     /locus_tag="VXE87_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843586.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPSIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIIALIYY
                     SLEDILIDDMNLLGLI"
BASE COUNT          684 a          266 c          379 g          759 t
ORIGIN      
        1 atttaggtat ttcatttatt gaagtttcac atcattatga cttaaatgac aagagataca
       61 ctgatatata taaattggaa aatggaacac ttttcaaaat taagtgattg gaggcaagaa
      121 tatggataaa gattatatat taaaagtgaa agggctgtat catcaatttt tactaggaaa
      181 taataaaacg ttgcaagtgc tgaaaaatgt ttctctttct gcttcgagag gagaatttat
      241 aagtattcta ggaattagtg gttctggaaa gtcaacttta ttaaaatgta tttctagttt
      301 gcttgaacca acaagtgggg aagtaatttt aaatggaatc aacccctata aaatcagaaa
      361 tgcaaaattg tcaagtataa gacgtaacga agtatctttt atatttcaag catacaattt
      421 aataccttcc ctgccggtaa tagaaaatat agcacttcct ttgcgattat cacaaaaaaa
      481 attaactatt aaaaatgtag aaaacttact caaaagaatg aagtttaatg ctggcttaaa
      541 cgattttgtt ggaactctgt ctggtggaga acaacagaag gttgctatag ctagagcggt
      601 tattgctgat agtgatataa tatttgctga tgagccaact ggggctttag acagcgtttc
      661 tcgtgaagta atttttgaat tattgagaga gttagtaggg gcgggtaagt gtgtaattat
      721 ggtaacgcac gatatagaat tggcctcgaa aactgatcgt gcattaatat tgaaagatgg
      781 aaaaattttc aaagaacttc atagacctag cggggaagag ttgtataaaa tcttagaggt
      841 acaatcaact acggaggaat agagatgctc agattagttt actatcaatt tttacataat
      901 aagaaacaat ggttaggcgt ttcaccagta atttttgttt cgagtttagt tatgggattg
      961 gctgttaatg gggtaattaa tgttgagaat aattcgcaag tatttgtcgg acttccagat
     1021 cctaaaccaa tttttatgtt tccgatagta ttcggaggag taacattatt ctttgtgctc
     1081 tctaacataa taaatatgtt ggttgaaatt tttagagatg attacgaact tctggaggtg
     1141 ttgggagcaa gtctccttca actatcattt cttgtggggg gacagatttt tatcatttcc
     1201 tcgattatta gttttattgc atatctatgc tctatatttg ttacgtcaaa ttattattat
     1261 tttttacaat actttttcgg ggaaaatata ttacctgata tccaatttca aacgagtgct
     1321 gttggatgta tcattacagt agtgttgatt tcatttttag cctttctaag tggttgcttt
     1381 tatacgttca agaagattag aaataggaag agttctaaaa taaggcatgt tctttcaata
     1441 gtaaaaagaa tactgctatt ggctggtttt agtgttatct ggttgctttc tttgcaacaa
     1501 attttccaag atagcacaat tttagcgaag gcccagataa tattcaatat tgtaatctta
     1561 gatattgtga ttatttatca attatctcct tctatacagt catgttttat caaactactt
     1621 tctataatta tatttagaaa taattttatg ttcattgttt cgaagtggaa tttactatat
     1681 cgtaagcctt atataaaatc tatcagtgct gcaattacag gagctatatt actaatttct
     1741 agttttcaaa tgatttctca gaatatacta tctcaatttc aagatgacag tgatttagag
     1801 ctaaaagtgg catttattgt ctatgtagga gcaccaattt tgatagtact tgcaaatatt
     1861 atttcaattg catttttgtc atcgcatcaa gaaaggattg agattcagca atttgaaatt
     1921 ttaggaactt ctaattacca gatggttaag attaaagttg gtgaggctat atttttgaca
     1981 tttgttactt cattaattgc atttttactt aacattaaaa ttattgcttt aatatactac
     2041 tctttagagg atattttaat agatgatatg aatcttttgg ggttaata
//
LOCUS       DAVLIK010000114         1976 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLIK010000114 DAVLIK010000000
VERSION     DAVLIK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1976
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.114"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            140..581
                     /locus_tag="VXE87_002134"
                     /pseudo
     CDS             140..581
                     /locus_tag="VXE87_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            746..1045
                     /locus_tag="VXE87_002135"
     CDS             746..1045
                     /locus_tag="VXE87_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0843587.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1306..1629
                     /gene="tnpB"
                     /locus_tag="VXE87_002136"
                     /pseudo
     CDS             1306..1629
                     /gene="tnpB"
                     /locus_tag="VXE87_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1766..>1976)
                     /locus_tag="VXE87_002137"
     CDS             complement(1766..>1976)
                     /locus_tag="VXE87_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843588.1"
                     /translation="FAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRTLEDVMNQLQDV
                     IQGLEKEVIKSIVNRRWTRMLFESR"
BASE COUNT          655 a          389 c          339 g          593 t
ORIGIN      
        1 tatactacct gttcgctcac aataagagag aactttttta cgaaaatcta ttgaatatgc
       61 cataagaaga ttataccaca ttgtgtacta tttttggttc atttcactat aataataacg
      121 atactagata atgaggaaaa tgcaatggca aacccaactt tcggagaaaa aagcgaatac
      181 agactatatt gctcgctatg gcgtatatgc agttatccct aatcctgaac aaaaacaaat
      241 tgttcttgtt caagaaccaa atggtgcttg gttcctacca tgtggagaaa ttgaagcagg
      301 tgaaaatcat caggaagccc taaagcgtga gttgattgaa gagcttggtt tcacagcaga
      361 aattggtacc tattacggac aagctgacga atatttctat tctcgtcatc gtgataccta
      421 ctactccaat cctgcctacc tctatgaagc aactcctaaa gccactagaa aactttaatc
      481 atattgcctg gttccctatt gacgaggcta tcaaaaacct taaacgtggt agccataaat
      541 gggccattga atcttggaaa aaacagcata agattgacta atactcttcg aaaataaaat
      601 tcaaaccacg tcagcgtcgc cttaccgtac tcaagtatag cctgcggcta gcttcctagt
      661 ttgctctttt attttcattg agtataaatc aagcgacttt attcaaaaag tgctataata
      721 gaattagaaa atcggaggaa atattatgaa gcttatcaat acgacaaact cacactcgca
      781 acttgtaaaa agtcagctag aaagtaccga tgcaaccctt gttgaggttt attctgcagg
      841 gaatacagat gttattttta cccaagctcc gcttcactat gaaatcctca tctcaaacaa
      901 acaccgtgct attcgtgagc ctgaaatcga aaccattcaa gaatttttct tgaaacgtaa
      961 aattgataag acctctgttg atgaagccaa tatcaagaca ctctactcag agaaattaat
     1021 tggaatttca atcccaatca agtaagaaaa ttgagtaaaa actcgatttg agagaaagtc
     1081 caataagtct ttccataaca aaacgcatag taacaagagt ttctacaccc actattatac
     1141 gtttttatca ttttgaaatc tgctgctaat caatgaagaa gcaaagatca aactaggcag
     1201 ctagttacaa gttacgtaag cgcgtcataa caaggtatct atcctaattc cccaacttcc
     1261 agtatactag ataaaaaata attatcagag gaaaagtatt gtactatgat gattctacta
     1321 agtgatttag gtcaagttca ccttgtttgt ggcaagacag atatgaggca gggaatagac
     1381 tcattagcct atgtagttaa aacccacttt gaattggatc ctttctcagg tcaagttttt
     1441 ctcttttgtg gtggacgtaa agaccgcttt aaagcccttt actgggatgg tcaaggattt
     1501 tggctactat ataaacgctt tgagaacgga aaactgactt gaccaagtac agaaaaggat
     1561 gtcaaagctc tcgcacctga acaagtagat tggcttatga agggcttttc tatcactcca
     1621 aaaatatagt agattgaaac tagaatagta cacctctgct tctaaaacat tgttagaaat
     1681 cgatttgtcc tgttcttatt tcattttact ataaatccat cagaaagtcg tgatttctat
     1741 tgaaatgagg actttctttt tatactcatc tgctttcaaa aagcattcta gtccatctcc
     1801 gattaacgat ggactttatc acctccttct ccagtccttg tatgacatct tggagttgat
     1861 tcatgacatc ttccaaagtt cgaaaggcct tattcttaaa tccacgttta cgaatctctt
     1921 tccacacttg ttcaatgggg ttcatctctg gtgtgtatgg aggaataaat gcaaag
//
LOCUS       DAVLIK010000115         1927 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLIK010000115 DAVLIK010000000
VERSION     DAVLIK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1927
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.115"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..142)
                     /locus_tag="VXE87_002138"
     rRNA            complement(<1..142)
                     /locus_tag="VXE87_002138"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            complement(267..339)
                     /locus_tag="VXE87_002139"
     tRNA            complement(267..339)
                     /locus_tag="VXE87_002139"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(304..306),aa:Ala,seq:tgc)
     gene            complement(391..>1927)
                     /locus_tag="VXE87_002140"
     rRNA            complement(391..>1927)
                     /locus_tag="VXE87_002140"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          426 a          585 c          409 g          507 t
ORIGIN      
        1 ggtactacct gttgggttcc cccattcgga aatccctgga tcatcgctta cttacagcta
       61 cccaaggcat atcgtcgttt gtcacgtcct tcgtcggctc ctagtgccaa ggcatccacc
      121 gtgcgccctt attaacttaa ccttattttc tgacctttca gtcataaact cttattaata
      181 ctacagcgtt ttcggtttat tttcttgtta ctatttgata tagatattca attttcaatg
      241 tgcattactt ggtgatctct caccaatgga gcctagcggg atcgaaccgc tgacctcctg
      301 cgtgcaaagc aggcgctctc ccagctgagc taaggcccca caagacctct caagactaaa
      361 caagaccaat gcgcagttcc ttatccttag aaaggaggtg atccagccgc accttccgat
      421 acggctacct tgttacgact tcaccccaat catctatccc accttaggcg gctggctcct
      481 tacggttacc tcaccgactt cgggtgttac aaactctcgt ggtgtgacgg gcggtgtgta
      541 caaggcccgg gaacgtattc accgcggcgt gctgatccgc gattactagc gattccgact
      601 tcatgtaggc gagttgcagc ctacaatccg aactgagact ggctttaaga gattagcttg
      661 ccgtcaccgg cttgcgactc gttgtaccag ccattgtagc acgtgtgtag cccaggtcat
      721 aaggggcatg atgatttgac gtcatcccca ccttcctccg gtttattacc ggcagtctcg
      781 ctagagtgcc caactaaatg atggcaacta acaatagggg ttgcgctcgt tgcgggactt
      841 aacccaacat ctcacgacac gagctgacga caaccatgca ccacctgtca cctctgtccc
      901 gaaggaaagc tctatctcta gagcggtcag agggatgtca agacctggta aggttcttcg
      961 cgttgcttcg aattaaacca catgctccac cgcttgtgcg ggcccccgtc aattcctttg
     1021 agtttcaacc ttgcggtcgt actccccagg cggagtgctt aatgcgttag ctacggcact
     1081 aaaccccgga aagggtctaa cacctagcac tcatcgttta cagcgtggac taccagggta
     1141 tctaatcctg tttgctcccc acgctttcga gcctcagcgt cagttacaag ccagagagcc
     1201 gctttcgcca ccggtgttcc tccatatatc tacgcatttc accgctacac atggaattcc
     1261 actctcccct cttgcactca agttaaacag tttccaaagc ctactatggt taagccacag
     1321 cctttaactt cagacttatc taaccgcctg cgctcgcttt acgcccaata aatccggaca
     1381 acgctcggga cctacgtatt accgcggctg ctggcacgta gttagccgtc cctttctggt
     1441 aagataccgt cacagtgtga actttccact ctcacactca ttcttctctt acaacagagc
     1501 tttacgatcc gaaaaccttc ttcactcacg cggcgttgct cggtcagact tccgtccatt
     1561 gccgaagatt ccctactgct gcctcccgta ggagtctggg ccgtgtctca gtcccagtgt
     1621 ggccgatcac cctctcaggt cggctatgta tcgtcgcctt ggtgagccgt taccccacca
     1681 actagctaat acaacgcagg tccatctggt agtgatgcaa gtgcaccttt taagcaaatg
     1741 tcatgcaaca tccactctta tgcggtatta gctatcgttt ccaatagtta tcccccgcta
     1801 ccaggcaggt tacctacgcg ttactcaccc gttcgcaact catccagaga agcaagctcc
     1861 tccttcagcg ttctacttgc atgtattagg cacgccgcca gcgttcgtcc tgagccagga
     1921 tcaaact
//
LOCUS       DAVLIK010000116         1860 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLIK010000116 DAVLIK010000000
VERSION     DAVLIK010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.116"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..988)
                     /locus_tag="VXE87_002141"
     CDS             complement(<1..988)
                     /locus_tag="VXE87_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV0843589.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPFGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNLSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELL"
     gene            complement(1001..1750)
                     /locus_tag="VXE87_002142"
     CDS             complement(1001..1750)
                     /locus_tag="VXE87_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0843590.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCSDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          645 a          339 c          210 g          666 t
ORIGIN      
        1 tcaatagttc attaattata cttaaaatag ctgactcttt gtaattatct gaattatatt
       61 tcatccccaa tttatatatt cctactatct ttggctttcg ttccaatatt tgtttaacta
      121 tgaactgttt tctatttgtg tttgaaatat caatcgcttc tatcactggg gcatttattt
      181 ctataaattc tttttttaat tgtttagtat ctttgggaag acaatatcct ccaaatccaa
      241 aagaaagatt attataaaaa tttccaattc ttggatctaa acaaacacct tttattacaa
      301 cttcagcatt taaacttctc ctctcagcaa aagaatctag ttcattaaaa aaagcaacac
      361 ggagagctaa gaatgtgtta gaaaaaagct taattgcttc tgcttcagta ggagaaacta
      421 acataacatt tttaatattg gcagtactat gagtactaat cgaaaggaac aactctgcaa
      481 tttttcttcc ttcaactgtc tcatctccaa caactatgcg acttggatat aaattatcat
      541 atatagaaca accttctctc aaaaattcag ggacaaaaat gatatttttt gtatcaaaca
      601 gcctttttaa tttgtttgaa aagccgaacg gaactgttga ctttaaaata atctttccat
      661 taggttttac cctcagaatc ttcgataccg tttgttcgat ttcatatgta ttaaaactac
      721 caattttctc atcataatct gtcggaagcg caataatata ataatcaata ttatttttaa
      781 tttcagaaaa tgtatcaaaa aaagtaatat ttaagttatt ctcgcaaaaa aacttcataa
      841 gctcttcatt tttagatgga agaatgccct tttttaaatt atttattttt acagaatcta
      901 tatcatatgc aacaacttta tatttagatg caaatagtaa cgcgtaggcc agcccaacat
      961 gccccaaacc aattactgct atattcataa aactacttcc ttatttctta atccaaaatc
     1021 taatagaata agctgcccca ttccttaaat acaactcttt aatattgttt aaaagttttt
     1081 caactgattt ccagattatc aaaatctgag atttatagca caatattgat gatattctat
     1141 caatataatg tttttcatca agttcctctt gatacatttt taattcttta gtttttccca
     1201 tataactaac catactacta tcacttacat atgggaagtc ctcataatat attactttat
     1261 aacgcataaa ttcaagcgcc cttccaatac tattcacaaa aacatgatca acatggtcac
     1321 caagtgaaag cggacaatat acgacacatt tatcgtctaa atgcattaac agctctttta
     1381 tgatatcatt ctttaatgtg tcctcatttt ttaattcact atagatatga cggtatagaa
     1441 aattgccatt tctatctttc ctatagagac attcatagta cgataagtgt ctaaaatcac
     1501 attgtagacg ttcacaagct aacctgtctt ctttcttcct ttcttcaatc ggatatttcc
     1561 caaggttaca caacttatga aattgcttag cagagggctg tagctgttgg ctcaaagggt
     1621 aaccagaaaa tatagtaata acaagtacaa tttctccttc tgaagttaat tttgaaatat
     1681 aatcactaca ggaaaaaatt gcgtcatcta aatgtggaga taaaaagata tacttagtat
     1741 tgttactcat aaccattccc tctacaattt atctaaaaac tcactaagtg tctgattaaa
     1801 ttccacatca tcaaaaaaat tcaccttatt cttaataatg aatatttcgt taaataaaca
//
LOCUS       DAVLIK010000117         1762 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLIK010000117 DAVLIK010000000
VERSION     DAVLIK010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.117"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            46..1386
                     /locus_tag="VXE87_002143"
     CDS             46..1386
                     /locus_tag="VXE87_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0843591.1"
                     /translation="MGDHAILNHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKY
                     NNTADSDIDELLTAFDGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPE
                     NTFMVYDDSIERKPLFAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQN
                     EQVTPHNLGQIPIIEYRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLY
                     GTQLADTPEDAKVAMKILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYT
                     FSHVPNLTDENFAGNTSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQ
                     IALESHSIVPQFSRGLPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEE
                     EKKKNMEDMPMFNKDNTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            1295..>1762
                     /locus_tag="VXE87_002144"
     CDS             1295..>1762
                     /locus_tag="VXE87_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEV0843592.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTG"
BASE COUNT          574 a          334 c          412 g          442 t
ORIGIN      
        1 cataacactg aaagctcacg cttgaagaat ttaaaaagct actacatggg tgatcatgct
       61 attttaaatc acaagagacg caacgtgaac gcaccgaatt acaagacggt agctaatcat
      121 gccaaggata tcgcagacac ggctacaggc tattttatgg gcaatcctat taagtataac
      181 aatactgctg acagtgatat cgatgaacta cttacagcct ttgatggtgc tgagattgac
      241 caagtagatg ctcagaatgc tttgaacatg gctatctatg gtcgtgctta cgagtacatc
      301 tatgctaaag agggtatgac tgagttggat tcaactagta ttgatccaga aaataccttc
      361 atggtctacg atgatagtat tgagcggaag cctttgtttg cggtctatta ctatgaagta
      421 aaagacgata cgaaagacac taccaagtac caggctgagg tctttaccga aaatctgcac
      481 tatcacatgg tgctgagaag tacagattca ggaacaactc agaatgagca ggtaacccct
      541 cacaaccttg ggcaaatccc aattatcgaa tatcgcaaca atcactttgc gatcggtgac
      601 tatgagcaac aaattagctt gatagacgct tataattcct tgatggggaa tcgtgtcaat
      661 gataaggaac aggctgtaga gtctatcctt gtcttgtatg gcacgcagtt agcagacact
      721 ccagaagacg ctaaggtagc gatgaagatt ctttctgaag aaggtctttt ggaattaccg
      781 ggcgatagtg caagagctga gttcttgaag aacacgttgg acgaaagtgc tactgaaatc
      841 ttgcgtacag ctcttaaaga ggacatctac acatttagcc atgtgcctaa tttgactgat
      901 gagaatttcg cagggaatac atcaggcgta gccatggaat ttaagctgat gggccttgag
      961 atgattacta agaccaagga agcgaactat aagcgaggat tgcgtcagcg tattgcgatt
     1021 tttgctcatt acttgggtat gaaacagatt gcactagagt ctcattcaat cgttccacaa
     1081 ttcagtcgtg gtttgcctaa gaacttgtta gaaatctctc agatcgtgaa caaccttgaa
     1141 ggtaaagtga cgaatagaca gcttatttct ctcttgccgt ttgtggaaga ccctgacgct
     1201 gaactggaag ccttggaaga agaaaaaaag aagaacatgg aagacatgcc gatgttcaac
     1261 aaagacaaca cgaaacccga agacgaggta gaggatgaag aatcaggagt attgggcgaa
     1321 gaggaaagcc aatctgattt accagcagat ggacaaggcc gaaaagcagg cagaccagtt
     1381 cgataaggtc tatcaggaag ccaagactta cttggataag gaagtcaata agatttttga
     1441 taagttccaa cgtgattatg gtctaagtca ggtagaagct agacaagtct tgaagaacat
     1501 gaaagacaag aaaaatctga atgaacttcg taaagtgctt gaagcaagac cgaatgatcc
     1561 aaatattcaa agactactgg ctgacttaga tagtccggct tattctttcc gtatgaagcg
     1621 tctagaacgt ttgagtgatg atttagaccg tatgcgtgaa tctatctatc attcagaaaa
     1681 gacaggctca gacgcctttt atagcgacct gatgaaggat agttactaca aggctacctt
     1741 tgacctgcag cagcagacag ga
//
LOCUS       DAVLIK010000118         1762 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLIK010000118 DAVLIK010000000
VERSION     DAVLIK010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.118"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..468)
                     /locus_tag="VXE87_002145"
     CDS             complement(<1..468)
                     /locus_tag="VXE87_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEV0843593.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTG"
     gene            complement(377..1717)
                     /locus_tag="VXE87_002146"
     CDS             complement(377..1717)
                     /locus_tag="VXE87_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0843594.1"
                     /translation="MGEHAILEHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKY
                     NNTAEGDIDELLTAFDGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPE
                     NTFMVYDDSIERKPLFAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQS
                     EEATPHNLGQIPIIEYRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLY
                     GTQLADTPEDAKVAMKILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYT
                     FSHVPNLTDENFAGNTSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQ
                     IALESHSIVPQFSRGLPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEE
                     EKKKNMEDMPMFNKDNTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
BASE COUNT          441 a          421 c          334 g          566 t
ORIGIN      
        1 tcctgtctgc tgctgcaggt caaaggtagc cttgtagtaa ctatccttca tcaggtcgct
       61 ataaaaggcg tctgagcctg tcttttctga atgatagata gattcacgca tacggtctaa
      121 atcatcactc aaacgttcta gacgcttcat acggaaagaa taagccggac tatctaagtc
      181 agccagtagt ctttggatat ttggatcatt cggtctcgct tcaagtactt tacgaagttc
      241 attcagattt ttcttgtctt tcatgttctt caagacttgt ctagcttcta cctgacttag
      301 accataatca cgttggaact tatcaaaaat cttattgact tccttatcca agtaagtctt
      361 ggcttcctga tagaccttat cgaactggtc tgcctgcttt tcggccttgt ccatctgctg
      421 gtaaatcaga ttggctttcc tcttcgccca atactcctga ttcttcatcc tctacctcgt
      481 cttcgggttt cgtgttgtct ttgttgaaca tcggcatgtc ttccatgttc ttctttttct
      541 cttcttccaa ggcttccagc tcagcgtcag ggtcttccac aaacggcaag agagaaataa
      601 gctgtctatt ggtcactttg ccttccaaat tgttcacaat ctgagagatt tctaacaagt
      661 tcttaggcaa accacgactg aattgtggaa cgattgaatg agactctaaa gcaatctgct
      721 tcatgcctaa gtaatgagca aaaatcgcaa tacgctgacg caatcctcgc ttatagttcg
      781 cttccttggt cttagtaatc atctcaaggc ccatcagctt aaattccatg gctacgcctg
      841 atgtattccc tgcgaaattc tcatcagtca aattaggcac atggctaaat gtgtagatgt
      901 cctctttaag agctgtacgc aagatttcag tagcactttc gtccagcgta ttcttcaaga
      961 actcagccct tgcactatcg cccggcaatt ccaaaagacc ttcttcagaa agaatcttca
     1021 ttgctacctt agcgtcttct ggagtgtctg ctaactgcgt gccatacaag acaaggatag
     1081 actctacagc ctgttcctta tcattgacac gattccccat caaggaatta taagcgtcta
     1141 tcaagctaat ttgttgctca tagtcaccga tcgcaaagtg attgttgcga tattcgataa
     1201 ttgggatttg accaaggttg tgaggtgttg cctcctcgct ctgagttgtt cctgaatctg
     1261 tacttctcag caccatgtga tagtgcagat tttcggtaaa gacctcagcc tggtgcttgg
     1321 tagtgtcttt cgtatcgtct tttacttcat agtaatagac cgcaaacaaa ggcttccgct
     1381 caatactatc atcgtagacc atgaaagtat tctccggatc aatactagtt gaatccaact
     1441 cagccatacc ctctttagca tagatgtact cgtaagcacg accatagata gccatgttca
     1501 aagcattctg agcatctact tggtcaatct cagcgccatc aaaggctgta agtagttcat
     1561 cgatatcacc ttcagcagtg ttattgtact tgataggatt gcccataaaa tagcccgtag
     1621 ctgtatctgc aatatccttg gcatgattag ctaccgtctt gtaattgggt gcgttcacat
     1681 tgcgtctctt gtgttctaag atagcatgct cacccaaata gtagctttta agcttcttca
     1741 aatgtgagct ttcagtgtta tg
//
LOCUS       DAVLIK010000119         1669 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLIK010000119 DAVLIK010000000
VERSION     DAVLIK010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.119"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            13..1014
                     /locus_tag="VXE87_002147"
     CDS             13..1014
                     /locus_tag="VXE87_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0843595.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    1226..1455
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT          559 a          223 c          336 g          551 t
ORIGIN      
        1 tagaggactg aaatgaaaaa tataaatggg aaaaaggtaa ctatttatga tattgcacgt
       61 ttatcaggtt tttctccaaa aacagtttca cgagttatta atggtggagt aaatgttaaa
      121 gaagaaactt atcaagcgat tcaaaaagtt atagaggaat tgtcgtatat tccaaatgcg
      181 tatgcaaaaa atttaactaa aaaagaagct ataaatatat tgatttctgt aaaaaaaatc
      241 gactcttttc ctttaatttg gtttcatacg ctgttagata aagtgttacg gacgtgtaaa
      301 gaatttggtg ttaatgctat agttgagtac tttggagagg aggatacaat tagtaattcg
      361 attatatcaa gcacaggtag cctagtagat ggtgttattg ttttttatga aagtgtagat
      421 gatatcagaa ttcagtattt aaagaagaac catatgcctt ttcttgtttt cggtgaatct
      481 caaacgtctg gagtagtcta tgtatctaat aataattttc aagctactta tgatatgatg
      541 aaagctgtaa ctgaagaaaa atttaaaaat atgtggttgc ttatgggagg agaatctcat
      601 gttaataagg atcgtgaaag aggtgtgcgt tcttttctga atgataaaaa ttactttatg
      661 gatttaaaag tcatttatgg attatctaca attgattcag tttattctta tgcaatgcag
      721 cacttgacta cccaaaatta tccggacatt atttttgttt caggagatga aaaggttcag
      781 ggcttgattc gtgcgtgcta tgagaaagga attcttattc cagatgatat ttctattatt
      841 ggatttgata atattcctat ttctcagtat tatactccag ctttgtctac aattgctccc
      901 aattatgtta aattggctaa agaaatgata gaaggtgttt tagcaattat taaaggggaa
      961 agtgtcacat ctgttgaagt ttctcctaaa tttgttagga gacagagttt ctagtattgt
     1021 ttaattcttg aaaatcctag tggaaaagat ggagtgttct aaaataagtt ctgtttagcc
     1081 tccattcagt ttctattgag ttggatccaa tttctaacaa gtgggacatg ttcatgttcg
     1141 atctaaggaa gacatggtca cattcgaatg atattttcaa aaaaatcgta aaaaagtctt
     1201 gacaaagaaa aaacaaagta ttaaaataag ttcaacaaat cagaaaagta actatttttg
     1261 atcttcaggg agcctgtggt ggttgtgaat aggtggttgg aagtagtgaa agtgggctga
     1321 ttttgaaaat gaatttgaaa taatgaaaat tcggtgcgca caccttacag tgcagcttgt
     1381 tgttaaacaa ggcagagatg taaagggata gtccctttat aattgaggtg gcaccgcgtt
     1441 accaacgccc tcacacggaa gtatattctg tgtgtgggct tttttctatc cgtcgtttgg
     1501 tttatctttt attagggcct taagtcgctt tgatgaactt gagttctatc tacagctcct
     1561 tgcctactac taaaagcaaa caaaaaggct ggactaatac gaaaaaagct agtaatactc
     1621 aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaaa
//
LOCUS       DAVLIK010000120         1637 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLIK010000120 DAVLIK010000000
VERSION     DAVLIK010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.120"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..>1637
                     /locus_tag="VXE87_002148"
     CDS             <1..>1637
                     /locus_tag="VXE87_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843596.1"
                     /translation="LSAIQEYVNKNGQRQEALQRYTREESTRQATAVRELVNRDFVGK
                     VTYQEDVKGINQRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQI
                     SGLSNRLTSSEQGATTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRIS
                     DQVSANKANADSQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVARM
                     ALTNQLFQVEVGKYSVSGPNLIKNSDFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMR
                     LSNATKNENFLYSHRFNLERNTDYVLNFRGFNNSALASYDVYILGRRAGESDGFTIVK
                     KVVSSKKLSTSRCEDVSVTFNSGEMDNAYIRFDNNGSSSGTADLYITEVDLYKGYKPR
                     TWQPHPEDVVADANKKLEATQTKMTLLTGSWAVQNINSAGDIISGINLGANGHNRFVG
                     KLTHITGETLIDRAVIKSAMVDKLKTGNFEAGSVTTTILEAEAVTAEKLKVDNALIKK
                     LTANDAFIDQLTSKRIFSTKVESVISSSTFLEAYQGR"
BASE COUNT          552 a          296 c          360 g          429 t
ORIGIN      
        1 ttatcagcta ttcaggaata tgtaaataaa aacggtcagc gacaggaagc cctacagcgc
       61 tatactcgtg aggagagcac gagacaagcg acagcagtcc gtgagctggt caatcgtgat
      121 ttcgttggta aggttactta tcaagaagat gttaagggta tcaatcagag gattgaagct
      181 gttaaaacta gtgcgaataa agacatcgct agtcaaatcg ctagctatcg tcaatctgta
      241 gatggtaagt tcacggatat ttcaagtcag ataactactt ataagcaaga tgtgggcggt
      301 caaatcagtg gtctatcaaa tagacttaca agcagtgagc aaggagccac tactcagatt
      361 tcaaatattt caaatcggat aaacagtaat aaacaaggca cagataatca gatttcaaat
      421 ttaaagactc aggtcgctac aaacaaggat aatgctgaac gacaaatggg tagaatatct
      481 gatcaggttt ctgcaaacaa agcgaatgct gatagtcaat ttgcgaatgt gaccaatcaa
      541 ctagcgcgaa aagtagagac tactgacttc cagcgtgtta aggaaaccag taaactttac
      601 gagcggattt tgggcaatac tgaaaatgga attgcggata aggttgctcg catggctctg
      661 accaatcaac tgtttcaggt tgaggttggg aaatatagtg taagcggccc taacctcatt
      721 aagaatagtg attttaaaaa tgctacgaat gaatggggct caactcaaaa tttaggaaga
      781 ttggttaagc atagctttta tcacaacggg cagaaagacc ttatgcgttt aagtaatgca
      841 actaaaaacg aaaacttttt gtatagtcac cgttttaatc ttgaacgaaa tactgactat
      901 gtactgaatt ttagaggatt taacaacagt gctctcgcaa gctatgatgt ttatattttg
      961 ggacgaagag caggcgagag cgatggattc acaatcgtta agaaagttgt tagcagcaag
     1021 aaactatcta cctctagatg cgaagatgtc tcagtaactt ttaattccgg agaaatggat
     1081 aatgcttaca ttcgttttga taacaatggc tcatcatcag gaacagctga tttgtatatt
     1141 acagaagttg acttgtacaa aggttataaa cctagaacat ggcaaccaca tccagaagat
     1201 gtggtcgcag atgcgaataa gaagcttgaa gccacgcaaa caaaaatgac tctactaact
     1261 ggctcatggg cagttcaaaa catcaactcg gctggagata tcatctctgg aatcaatctt
     1321 ggcgccaatg gacataaccg ctttgttggg aaattgaccc acatcactgg agagaccctg
     1381 attgacagag cagtcatcaa gtctgccatg gttgataagt tgaaaacggg caattttgaa
     1441 gctggttcgg tcacgactac gatattagaa gctgaagcgg taactgctga gaagttgaaa
     1501 gttgacaatg cgcttattaa aaaattaact gcaaatgatg cttttattga ccaactgaca
     1561 tctaaacgta tcttctctac taaggttgag tccgtcattt ctagttcaac cttcctagaa
     1621 gcctatcaag gtcgaat
//
LOCUS       DAVLIK010000121         1581 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLIK010000121 DAVLIK010000000
VERSION     DAVLIK010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1581
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.121"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            173..>1581
                     /gene="pcpA"
                     /locus_tag="VXE87_002149"
     CDS             173..>1581
                     /gene="pcpA"
                     /locus_tag="VXE87_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0843597.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNDGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKG"
BASE COUNT          621 a          212 c          250 g          498 t
ORIGIN      
        1 tttccttgac ttaaaattta aaaatgatat actgtgttta tagagagatg acaatttata
       61 aaatgtacta ctctattcta ctagataatg attgaataaa actttttata acaacggcta
      121 gcaaagttat aattttatat ctattagaaa ataaatatgt aaggaaattt aaatgaaaaa
      181 aactacaata ttatcattaa ctacagctgc ggttatttta gcagcatatg tccctaatga
      241 accaatccta gcagatactc ctagttcgga agtaatcaaa gagactaaag ttggaagtat
      301 tattcaacaa aataatatca aatataaggt tctaactgta gaaggtaaca taggaactgt
      361 tcaagtgggt aatggagtta ctcctgtaga gtttgaagct ggtcaagatg gaaaaccatt
      421 cacgattcct acaaaaatca cagtaggtga taaagtattt accgttactg aagtagctag
      481 tcaagctttt agttattatc cagatgaaac aggtagaatt gtctactatc ctagctctat
      541 tactatccca tcaagcataa aaaaaataca aaaaaaaggc ttccatggaa gtaaagctaa
      601 aactattatt tttgacaaag gcagtcagct ggagaaaatt gaagatagag cttttgattt
      661 ttctgaatta gaagagattg aattgcctgc atctctagaa tatattggaa caagtgcatt
      721 ttcttttagt caaaaattga aaaagctaac cttttcctca agttcaaaat tagaattaat
      781 atcacatgag gcttttgcta atttatcaaa tttagagaaa ctaacattac caaaatcggt
      841 taaaacatta ggaagtaatc tatttagact cactactagc ttaaaacatg ttgatgttga
      901 agaaggaaat gaatcgtttg cctcagttga tggtgttttg ttttcaaaag ataaaactca
      961 attaatttat tatccaagtc aaaaaaatga cgaaagttat aaaacgccta aggagacaaa
     1021 agaacttgca tcatattcgt ttaataaaaa ttcttacttg aaaaaactcg aattgaatga
     1081 tggtttagaa aaaatcggta cttttgcatt tgcagatgcg attaaacttg aagaaattag
     1141 cttaccaaat agtttagaaa ctattgaacg tttagccttt tacggtaatt tagaattaaa
     1201 agaacttata ttaccagata atgttaaaaa ttttggtaaa cacgttatga acggtttacc
     1261 aaaattaaaa agtttaacaa ttggtaataa tatcaactca ttgccgtcct tcttcctaag
     1321 tggcgtctta gattcattaa aggaaattca tattaagaat aaaagtacag agttttctgt
     1381 gaaaaaagat acatttgcaa ttcctgaaac tgttaagttc tatgtaacat cagaacatat
     1441 aaaagatgtt cttaaatcaa atttatctac tagtaatgat atcattgttg aaaaagtaga
     1501 taatataaaa caagaaactg atgtagctaa acctaaaaag aattctaatc agggagtagt
     1561 tggttgggtt aaagacaaag g
//
LOCUS       DAVLIK010000122         1568 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLIK010000122 DAVLIK010000000
VERSION     DAVLIK010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1568
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.122"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..>1568
                     /locus_tag="VXE87_002150"
     CDS             <1..>1568
                     /locus_tag="VXE87_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate binding domain-containing protein"
                     /protein_id="HEV0843598.1"
                     /translation="LSAIQEYVNKDGQRQEALQRYTREESTRQATAVRELVNRDFVGK
                     ATYQEDVKGINQRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQI
                     SGLSNRLTSSEQGTTTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRIS
                     DQVSANKANADSQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVARM
                     ALTNQLFQVEVAKNASNGQNLLQGTKDFSGGWKNKGANWKKHAEKYKGVDVLFKNNSW
                     NGVGQEIDAKIGEVYTFSLWMKSDWKNDTVNFYVNRNGSVEKGWGVPSETSVAITSEW
                     KRYSFTFKITVDGFIFPRVERLNQNTNLYIAGLKLEKGSYATPYTEAPEDTDEAIRSV
                     QSQLTGSWAVQNINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVDK
                     LKTANFEAGSVTTTILEAEAVTAEKLKVDNALIRKLTANDAFIDQLISKRIFSTKVES
                     VISSSTFLEAYQGR"
BASE COUNT          526 a          291 c          355 g          396 t
ORIGIN      
        1 ttatcagcta ttcaggaata tgtaaataaa gacggtcagc gacaggaagc cctacagcgc
       61 tatactcgtg aggagagcac gagacaagcg acagcagtcc gtgagctggt caatcgtgat
      121 ttcgttggta aggctactta tcaagaagat gttaagggta tcaatcagag gattgaagct
      181 gttaaaacta gtgcgaataa agacatcgct agtcaaatcg ctagctatcg tcaatctgta
      241 gatggtaagt tcacggatat ttcaagtcag ataactactt ataagcaaga tgtgggcggt
      301 caaatcagtg gtctatcaaa tagacttaca agcagtgagc aaggaaccac tactcagatt
      361 tcaaatattt caaatcggat aaacagtaat aagcaaggca cagataatca gatttcaaat
      421 ttaaagactc aggtcgctac aaacaaggat aatgctgaac gacaaatggg tagaatatct
      481 gatcaggttt ctgcaaacaa agcgaatgct gatagtcaat ttgcgaatgt gaccaatcaa
      541 ctagcgcgaa aagtagagac tactgacttc cagcgtgtta aggaaaccag taaactttac
      601 gagcggattt tgggcaatac tgaaaatgga attgcggata aggttgctcg catggctctg
      661 accaatcaac tgtttcaggt tgaggtggct aaaaatgcca gcaatggtca aaatttgttg
      721 caaggcacaa aagacttctc agggggttgg aaaaacaagg gtgcaaattg gaaaaagcac
      781 gctgaaaaat acaaaggtgt tgatgtccta tttaaaaata attcgtggaa tggcgttgga
      841 caagagattg atgcaaaaat tggtgaagtc tatacattca gcttatggat gaagagcgac
      901 tggaagaatg atacagtaaa tttctatgta aatagaaatg gatctgttga gaaaggttgg
      961 ggtgttccat ctgaaacatc ggtcgctata acaagtgaat ggaaacgtta ctcatttacc
     1021 ttcaaaatta ctgtggacgg cttcatcttt cctcgtgtag aacgacttaa tcaaaataca
     1081 aatctatata ttgcaggtct taaacttgaa aaaggatcgt atgcaacacc gtacaccgaa
     1141 gctcctgaag acacggacga agcgattcgc tctgttcaaa gccaactaac tggctcatgg
     1201 gcagttcaaa acatcaactc ggctggagat atcatctctg gaatcaatct tggcgccaat
     1261 ggacataacc gcttcgttgg gaaattgacc cacatcactg gagagaccct gattgacaga
     1321 gcagtcatca agtctgccat ggttgataag ctcaaaacgg ccaattttga agctggttcg
     1381 gtcacgacta cgatattaga agctgaagcg gtaactgctg agaagttgaa agttgacaat
     1441 gcgcttatta gaaaattaac tgcaaatgat gcttttattg accaactgat atctaaacgt
     1501 atcttctcta ctaaggttga gtccgtcatt tctagctcaa ccttcctaga agcctatcaa
     1561 ggccgaat
//
LOCUS       DAVLIK010000123         1528 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLIK010000123 DAVLIK010000000
VERSION     DAVLIK010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.123"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            29..1375
                     /gene="gdhA"
                     /locus_tag="VXE87_002151"
     CDS             29..1375
                     /gene="gdhA"
                     /locus_tag="VXE87_002151"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0843599.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEMMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHGGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVDQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          464 a          294 c          324 g          446 t
ORIGIN      
        1 taaaatatga caataaaagg agaacgatat gacatctgct aaagaatata tccaaagcgt
       61 gtttgaaact gtgaaagctc gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga
      121 atttttcaac actttagaac ctgtatttga aaaacaccct gagtatatcg aagaaaatat
      181 cttggcacgt attactgagc ctgagcgcgt ggtttctttc cgtgttcctt gggttgaccg
      241 tgatggaaaa attcaagtaa accgtggtta ccgtgttcaa ttcaactcag ctgttggacc
      301 atacaaaggt ggacttcgtt tccacccaac tgtaaaccaa ggaatcttga aattcctcgg
      361 atttgaacaa atctttaaaa atgtcttgac tggacttcct atcggtggag gtaaaggtgg
      421 atcagacttc gatcctaaag gtaaaacaga tgctgaaatg atgcgcttct gccaaagctt
      481 catgactgaa ttgcaaaaac acatcggacc atcacttgac gtacctgctg gtgatatcgg
      541 tgttggtgga cgtgaaattg gttaccttta cggtcaatac aaacgtctta accaatttga
      601 tgctggtgtc ttgactggta aacctcttgg atttggtggt agcttgattc gtccagaagc
      661 aactggttac ggtttggttt actatactga agaaatgctc aaagctaacg gtaacagctt
      721 tgctggtaag aaagtcgtta tttcaggttc aggtaacgtt gctcaatatg ctcttcaaaa
      781 agcaactgaa ctcggtgcaa ctgttatttc tgtttctgac tcaaatggtt atgtcatcga
      841 tgaaaatggt atcgacttcg atcttttggt tgatgttaaa gaaaaacgtc gtgctcgttt
      901 gactgagtat gcagctgaaa aagcaactgc tacttatcat ggaggttctg tatggactta
      961 cgctggtaac tatgatatcg ctcttccatg tgcgactcaa aacgaaatca acggtgaagc
     1021 agctaaacgt ttggttgatc aaggcgttat ctgtgtatct gaaggtgcca acatgccaag
     1081 cgaccttgat gccatcaaag tttacaaaga aaatggtatc ttctacggac ctgccaaagc
     1141 tgccaacgct ggtggtgtag ccgtttcagc ccttgaaatg agccaaaaca gtcttcgcct
     1201 ctcatggact cgtgaagaag ttgatggccg tctcaaagac atcatgacaa acatcttcaa
     1261 cacagctaaa acgacttcag aaacatacgg tcttgataaa gactaccttg caggagctaa
     1321 cattgctgcc tttgaaaatg tagcaaacgc tatgattgca caaggtattg tttaagattt
     1381 atttactcaa tcctcaatca ctacgattgg ggatttttag ttgagttaga cagttgggaa
     1441 attctaatta aatgaaataa aaactgaaca aatttattgc ggaattcaaa ccaatttcta
     1501 acatatttct agaaattaat ttgacttt
//
LOCUS       DAVLIK010000124         1520 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLIK010000124 DAVLIK010000000
VERSION     DAVLIK010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.124"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(16..174)
                     /locus_tag="VXE87_002152"
     CDS             complement(16..174)
                     /locus_tag="VXE87_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0843600.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLSWT
                     KVVQEKCK"
     gene            complement(246..695)
                     /locus_tag="VXE87_002153"
     CDS             complement(246..695)
                     /locus_tag="VXE87_002153"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843601.1"
                     /translation="MVNCEQLEAYRQLEEAALVGCWAHVRRKFFEVPPKQADKSSLGA
                     KGLAYCDQLFSLERDWEALPADERLQKRQEHLQPLLEDFFAWCRRQSVLSGSKLGRAI
                     EYSLKYEETFKTILKDGHLVLSNNLAERAIKSLVMGRSKRVQWTLLA"
     gene            complement(768..1358)
                     /locus_tag="VXE87_002154"
                     /pseudo
     CDS             complement(768..1358)
                     /locus_tag="VXE87_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1282..1476)
                     /locus_tag="VXE87_002155"
     CDS             complement(1282..1476)
                     /locus_tag="VXE87_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843602.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
BASE COUNT          410 a          337 c          287 g          486 t
ORIGIN      
        1 taatctggag atttcttatt tgcacttttc ttgtacaact ttagtccacg ataaataggc
       61 ctctaaaacc tctttgttta cgagagtttc ctcgtttgga agacattcta gaagatagga
      121 tagatatttc tcactattta gttgatgacg tttagctgtt tccaataagc tcataataat
      181 agctcttgct ttagctcctt caaaaacttt gagaaaacaa ccaccctcgc ttttttaaac
      241 tgagcttagg ctaaaagagt ccactggact cttttactcc gtcccataac caatgattta
      301 atggcgcgtt cagctagatt attggaaagg accagatgtc cgtcttttaa aatggtctta
      361 aaggtttctt catacttgag gctgtattca attgcccttc ctagttttga acccgataaa
      421 actgactgac gacggcacca agcaaagaag tcttccagta ggggttggag atgttcttga
      481 cgtttctgta gtcgttcatc agctggcaaa gcctcccagt ctctttccaa ggaaaataac
      541 tgatcacaat aagctaaacc tttagctcct aaggatgatt tatctgcttg cttggggggc
      601 acttcaaaaa acttccttct cacatgcgcc caacatccaa caagtgcagc ttcttccagt
      661 tgacgataag cttctagctg ttcgcagttt accaagctta gcgtcgcctt actcctaaac
      721 tttggactgc tatcgcatag gcagaactag aggactaaag tcctaagtta ctgccgcaac
      781 atgtcacaat gaacatagcc agaataatct cctaggaatt cttgtactac taaaccactc
      841 cgacgctgat catggtggta cagcgtgatt gcttgattct cagctttccc agacaaaaaa
      901 gtccaatagt aagtcaactg actatcactc tctagaaccc gataagaggt ttcatccgca
      961 tgaagtaagg gcttgagtca atagtctcgt tataaagggg ctttaggaat aggagctttc
     1021 acgattttat cactcggatt tttatcactg catgcttggc atttgtaagc gtgttggata
     1081 tgatctatgc gttttaattg cgcaggaata aagaccaatt cttgtccttg aagactccct
     1141 ccaatctctt ttagatctcc ctgacaatca gggcaaatcc tctcttctac ttgatgatga
     1201 acttcttctg aatcaaattg ggcaagaaga gcttggcgtt tccctttaga tttcttacgt
     1261 ttgtaggtaa tttcctctgt ttcaactggg aacatctcca tcttcctcag atggagactc
     1321 ttcctcaaaa aggttgagtt gtccagaggg gcaaacactt ttctcagagg attttccata
     1381 gagcttttga gtcagataag ccacttgttc acgaagaagg gcaagttcat tggtgagact
     1441 atcaattgta gcactctgtt gttgaatgat tttcaatctt cttccatgag cttccctctc
     1501 tgttttctaa ctttattata
//
LOCUS       DAVLIK010000125         1465 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLIK010000125 DAVLIK010000000
VERSION     DAVLIK010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.125"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            139..1317
                     /locus_tag="VXE87_002156"
     CDS             139..1317
                     /locus_tag="VXE87_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0843603.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT          543 a          261 c          209 g          452 t
ORIGIN      
        1 ttgattattt tttattatca atatataata aaaagagacc agtaagtaat gaaaagctta
       61 aaaagattaa catctacatt tatccatagc aaaaaatcat aggattttaa gaatctgaca
      121 actaggaaga aaactaatat gaccttatct aagaaacaat tacaactaag agctaaaata
      181 ctggaaacag tttacacatt aggtcccatt tcacgaattg aaatcgctac taaaacagga
      241 ataacacctg caacaactag cagtatcaca aatgatctga ttaaagaaaa tattctctta
      301 gaacttggtg aagacgaaca cgatacaagc gtagggagaa aaaaaatcct gctagacatt
      361 caagctaaac gattttacta cattggttgt gaactatctg aaaaacattt cacttttgct
      421 ttaggagata atctaggaaa tatcttaaag gaagagaaag aaattgttac taaacagtta
      481 atccaagaaa agggaaatca actcattaac cagacactaa agcaattctt aaataactgc
      541 tctgattatg aaatagaagc aattggaatc gcgctacctg gtcgctattt agataattat
      601 aaaataacaa caaacaatcc tttatggcaa catatcgact tagaaatgat tcaatcccac
      661 tttgataagc ctttgttttt ctctaacaat gttaactgta tggctatagg taaacgccta
      721 tttagtcgcc aacagaatga ccctaatttt gcttattttc attttgctag aggtatgcac
      781 tgttcttata tctacgacgg aaacatttat gggaaaggaa atctaatgat tggagaaata
      841 gggcatacag ttgtttcatc tgagggagaa gaatgtagct gcgggcgcaa gggatgctta
      901 caaacttttg ctggagaatc ttggttaatc aaaaaatcaa aaattctata tcatcaatct
      961 ccctattctc tacttcctag tttagtcaaa aatgccgatg atattgatat ccaagttatt
     1021 ttaaccgctt atcaattagg tgacactgga ataatcacac ttatccatca agccttactc
     1081 tatcttagtc aaaccatttt aaatatcagt atgatgattg actctcaaaa aatctaccta
     1141 catagtcctt tactaacaaa tcaacacatc atccaaaaac tatatagtga aatgaactac
     1201 aaacccaaac tgctctataa tcgcctacct gaagtcatta ttgaacctta caatgatttt
     1261 acagccgcac actcagctat tgcactttgt ttgtatcata caattctaca ttcttaattt
     1321 tctattacat ttaataaata ggctaaaaag agggagtata tcataaaaag cgaataaacc
     1381 tgttttctga aaatcagaat tctgttttgt tcgctttctt tatatttgga attatactcc
     1441 tatctcccct ttttcataat gtata
//
LOCUS       DAVLIK010000126         1374 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLIK010000126 DAVLIK010000000
VERSION     DAVLIK010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.126"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..190
                     /locus_tag="VXE87_002157"
     CDS             <1..190
                     /locus_tag="VXE87_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0843604.1"
                     /translation="LKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTVLPDIKIKLP
                     IDSRGTPDWNYMERYRDR"
     gene            156..470
                     /locus_tag="VXE87_002158"
     CDS             156..470
                     /locus_tag="VXE87_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843605.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1154..1315
                     /locus_tag="VXE87_002159"
     CDS             1154..1315
                     /locus_tag="VXE87_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843606.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
BASE COUNT          586 a          168 c          243 g          377 t
ORIGIN      
        1 attaaaaaat aaagaattga ataaagaagt agcattctat ttaacttcaa ttattaggca
       61 agctttaaaa aatactgaat ataaagatca aatatctagc acagtattgc cagatatcaa
      121 aattaaatta ccgatagaca gtagaggtac tccagattgg aattacatgg aaagatatag
      181 agatagataa agagagagag ggagagatag ataaaaagtc cacccccatt ttttatggag
      241 aattcaaaaa tgtaaggtta agcaaagaag aatataaaaa tctaaaagaa aaattaaact
      301 cacacacaga tataatgata aataaactat ccagatacat ggaaagcagt ggtaagacct
      361 atcaaaacca ctatgtgaca atcttaaaat ggtatgaaga agataaagac aaactaagac
      421 agaaaggttt aaataaaaaa atgaattatg atgtaggaga atctttatag ataaaaagag
      481 gtggaaaggc actattaaag actttaagtc taaaaaggta tcaaagtatg ccagagataa
      541 aaaaatataa atatgacact ttaaaggcga ttagaaaatt aaagaaatgc tagaagactt
      601 ttagatgaca gttaccaaga gggtctaatt ttcactgcta cttatgcagt gggaatttga
      661 cctttttata taagcaaatt ctatttcaaa attggttacc aagaaagact tcttttcact
      721 gttaagtata agagggtaat ttatagaatt ttattacatt aagataaata ttttctgatg
      781 gtcaaatttt aaaaagatta ataactctcg ataaattttg aaccttaaca attgaataga
      841 ccaagacaag acgttaatta tttttggagc gtaataacct atccgtcaag atctttcggc
      901 tgaataattc ggcaaaaaaa gttctgctaa gtaaaaagaa agtgagcgat aagtaagagt
      961 ttgaatatag ggagggatac cctatccgct atgaagaaaa tgaggataat gatacttcta
     1021 aggttgaagc cggctcatcc ggaatagagg cggaggtgag attcctatgt tgctaatcca
     1081 aagcacttgt caatgtcaaa aaacttaatt aaacaaataa ttattagata taaaacttta
     1141 gaggaggtat atattggaca atgactggaa tggattggct gatttaatag caaatctgat
     1201 tgcaaaatat gctggtgctt tagatttaga taatctaccc gatccaacgc cagcaaaaaa
     1261 tcaagagatg aaaaatagtt ttgacatggc aaaaacacaa attgagacgg actaataaaa
     1321 gtgttataat atacttgaaa tgatagtcca aacttaaatt aaaaaaatta tata
//
LOCUS       DAVLIK010000127         1346 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLIK010000127 DAVLIK010000000
VERSION     DAVLIK010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.127"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..>1346
                     /locus_tag="VXE87_002160"
     CDS             <1..>1346
                     /locus_tag="VXE87_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NACHT domain-containing protein"
                     /protein_id="HEV0843607.1"
                     /translation="LYDFYEHVYLDDNNSDLIETSNTELIFEKTSNVILTGTGGIGKS
                     MLVKHIFINQVQQATSIPIFIELKSLNESDFSENELVDFIYQEVQNHHLNLEKKYFKA
                     TLEAGRYTIIFDGLDEVNPSKRSWLDKEIKEFVTLYNSNRYVLSSRPSEEFIGWNQFA
                     EYEIKKLNREQALSLIDKLNYDEKVKRRFYRELKDHLYDTHESFASIPLLLTIMLMTY
                     EAGASIPNNLTDFYNQAFYTLYQRHDASKSGYKRELKAKLTPEEFRNILAYIGLKTFF
                     EGKVDFDRTTLDEIITKYCFKNNLELKTNDIVYDATHSACMMLQEGVSLKFSHRSFQE
                     YFAAVGVNQLDDKLQKQILIKWSEADRNNIVAHKTFMNALFKIQKERTYKNLCIPIIE
                     RMDEKYSRMGDITEKIVTCFNYFICRKDSRENKLELHFLLTKEVHFYFSLQFLIFA"
BASE COUNT          510 a          168 c          220 g          448 t
ORIGIN      
        1 tttatatgat ttctatgagc atgtttattt agatgataat aattcagatt taatagaaac
       61 ctctaacaca gaattgattt ttgaaaaaac atctaacgtt attttgacag gaacgggtgg
      121 gattggtaaa tcaatgcttg taaagcatat ttttatcaat caagtacaac aagctacatc
      181 aattccaatt tttattgaat taaaatcact taatgaatct gatttctcag aaaatgaatt
      241 agttgatttt atttaccaag aggttcaaaa tcatcattta aatttagaaa agaaatattt
      301 taaagcgaca ttagaggctg gaagatatac aataattttt gatggtttag atgaggttaa
      361 tccttcaaaa cgttcttggt tggacaaaga aattaaagaa tttgtaacgt tatacaatag
      421 caatagatat gttttgtcgt caagaccgtc tgaggaattt attggttgga atcagtttgc
      481 tgagtatgag ataaaaaaat taaatagaga gcaagcgtta tccttaattg ataagttgaa
      541 ttatgatgag aaagtaaaaa ggcgtttcta cagagaatta aaggatcatt tatatgatac
      601 tcatgaatct tttgcttcta tcccactcct attaacaatt atgttaatga cttacgaagc
      661 tggtgcttct attccaaata atttaactga tttttataat caggcctttt atacattgta
      721 ccaaagacat gatgcatcta aatcaggata caaaagagaa ctaaaagcaa aattaactcc
      781 tgaagaattt cgaaatatat tagcctacat tggtttaaaa acattctttg aaggaaaagt
      841 agatttcgat agaactacac ttgatgaaat aattactaaa tattgtttta aaaataacct
      901 tgaattaaag acgaatgata tagtttatga tgcgactcat agtgcttgta tgatgcttca
      961 agaaggcgtt agtttaaaat tctctcaccg ttcattccaa gaatactttg ctgcagtagg
     1021 tgttaatcag ctagatgata aactccaaaa acagatacta attaagtggt ctgaagcaga
     1081 taggaataat attgtagcac ataaaacttt tatgaatgca ctttttaaaa tacagaaaga
     1141 aaggacttac aaaaatttat gtattccaat catagaaaga atggatgaaa agtatagcag
     1201 aatgggggat atcacagaga aaattgttac gtgtttcaat tactttatct gtagaaaaga
     1261 tagtagagaa aacaaattag aattgcactt tttactaaca aaggaagttc acttttattt
     1321 tagcttgcaa tttttaatat ttgcta
//
LOCUS       DAVLIK010000128         1255 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLIK010000128 DAVLIK010000000
VERSION     DAVLIK010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.128"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..977
                     /locus_tag="VXE87_002161"
                     /pseudo
     CDS             1..977
                     /locus_tag="VXE87_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1132..>1255)
                     /locus_tag="VXE87_002162"
     CDS             complement(1132..>1255)
                     /locus_tag="VXE87_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002203452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0843608.1"
                     /translation="ADKDKQDKLPNTGETTGTYLSILGMITAVFASLLYRSKKK"
BASE COUNT          399 a          257 c          206 g          393 t
ORIGIN      
        1 caaatccctc gtatcatcaa ccaaaagatt gctcaaaagt taattgaaaa gatttctatg
       61 accgatattg cccatcagct ttccatctca acttcaactg tcattcgaaa gctcaatgac
      121 ttccactttg agtgtaattt tagaaatctg cctgagatta tgtcttggga cgttgaaaca
      181 gtccggggag tgactgtttc aatcgggaga tggagatgag ctttattgcg caagattttg
      241 aaaagctcga tatcatcact gttcttgagg gaagaacaca agctatcatt cgaaatcact
      301 ttcttaaata tgatagagcc gtccgatgtc gcgtcaaaat tattactatg gatatgttta
      361 gtccttacta tgacttagct agacaacttt tcccgtgtgc taaaatcgtg ttggatcgct
      421 ttcacattgt acaacatctt agccgtgcta tgagtcgtat gcgtgttcaa atcatgaatc
      481 agtttcatcg aaaatcccat gaatacaagg ctatcaagcg ctactggaag ctcatacaac
      541 aggatagccg taaactgagt gataagcgat tttatcgtcc tacttttcgt atgcatttaa
      601 ccaataaaga gattttagac aagcttttga gctattcaca agacttgaaa catcactatc
      661 agctctatca actcttgctg tttcactttc agaataagga accagagaaa tttttcggac
      721 tcattgagga caatctaaag caggttcatc ctctttttca gactgtcttt aaaacctttc
      781 taaaggacaa agagaaaatc gtcaacgccc ttcaactaca ctattctaat gccaaactgg
      841 aagcgaccaa taatctcatc aaacttatca aacgaaacgc ctttggattt cggaactttg
      901 aaaacttcaa aaaaaggatt tttatcgctc tgaatatcaa aaaagaaagg acgaaatttg
      961 tcctttctca agcttagctt ttcttcaacc cactacagtt gacaaagagc cgattttatt
     1021 cgctttttat atttaaggtt agacttttgt ccctctttgt cgttaacaaa aatacaaaaa
     1081 tcgtcctcaa aaactttaat gtagctcaca aattggagag aatagcaaaa actatttttt
     1141 cttactacgg tacaataggc ttgcaaaaac tgcagtaatc ataccaagta ttgacaaata
     1201 agttcctgtt gtttctcctg tatttggcaa cttatcttgc ttatctttat cagca
//
LOCUS       DAVLIK010000129         1186 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLIK010000129 DAVLIK010000000
VERSION     DAVLIK010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1186
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.129"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..>1186
                     /gene="phtD"
                     /locus_tag="VXE87_002163"
     CDS             <1..>1186
                     /gene="phtD"
                     /locus_tag="VXE87_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0843609.1"
                     /translation="LIFDPAQITSRTARGVAVPHGNHYHFIPYSQMSELEERIARIIP
                     LRYRSNHWVPDSRPEQPSPQSTPEPSPSPQSAPNPQPAPSNPIDEKLVKEAVRKVGDG
                     YVFEKNGVSRYIPAKNLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAY
                     DLLARIHQDLLDNKGRQVDFEALDNLLERLKDVPSDKVKLVDDILAFLAPIRHPERLG
                     KPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDS
                     LSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNL
                     QYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERP
                     HS"
BASE COUNT          379 a          262 c          246 g          299 t
ORIGIN      
        1 gccttatttt cgacccagcg caaatcacaa gtcgaaccgc cagaggtgta gctgtccctc
       61 atggtaacca ttaccacttt atcccttact ctcaaatgtc tgaattggaa gaacgaattg
      121 ctcgtattat tccccttcgt tatcgttcaa accattgggt accagattca agaccagaac
      181 aaccaagtcc acaatcgact ccagaaccta gtccaagtcc gcaatctgca ccaaatcctc
      241 aaccagctcc aagcaatcca attgatgaga aattggtcaa agaagctgtt cgaaaagtag
      301 gcgatggtta tgtctttgag aagaatggag tttctcgtta tatcccagcc aagaatcttt
      361 cagcagaaac agcagcaggc attgatagca aactggccaa gcaggaaagt ttatctcata
      421 agctaggagc taagaaaact gacctcccat ctagtgatcg agaattttac aataaggctt
      481 atgacttact agcaagaatt caccaagatt tacttgataa taaaggtcga caagttgatt
      541 ttgaggcttt ggataacctg ttggaacgac tcaaggatgt cccaagtgat aaagtcaagt
      601 tagtggatga tattcttgcc ttcttagctc cgattcgtca tccagaacgt ttaggaaaac
      661 caaatgcgca aattacctac actgatgatg agattcaagt agccaagttg gcaggcaagt
      721 acacaacaga agacggttat atctttgatc ctcgtgatat aaccagtgat gagggggatg
      781 cctatgtaac tccacatatg acccatagcc actggattaa aaaagatagt ttgtctgaag
      841 ctgagagagc ggcagcccag gcttatgcta aagagaaagg tttgacccct ccttcgacag
      901 accatcagga ttcaggaaat actgaggcaa aaggagcaga agctatctac aaccgcgtga
      961 aagcagctaa gaaggtgcca cttgatcgta tgccttacaa tcttcaatat actgtagaag
     1021 tcaaaaacgg tagtttaatc atacctcatt atgaccatta ccataacatc aaatttgagt
     1081 ggtttgacga aggcctttat gaggcaccta aggggtatac tcttgaggat cttttggcga
     1141 ctgtcaagta ctatgtcgaa catccaaacg aacgtccgca ttcaga
//
LOCUS       DAVLIK010000130         1134 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLIK010000130 DAVLIK010000000
VERSION     DAVLIK010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.130"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(1..362)
                     /locus_tag="VXE87_002164"
                     /pseudo
     CDS             complement(1..362)
                     /locus_tag="VXE87_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            complement(455..592)
                     /locus_tag="VXE87_002165"
     CDS             complement(455..592)
                     /locus_tag="VXE87_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843610.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEVLNIRLEVK
                     N"
     gene            850..969
                     /locus_tag="VXE87_002166"
     CDS             850..969
                     /locus_tag="VXE87_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0843611.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT          371 a          185 c          179 g          399 t
ORIGIN      
        1 agtaaagtat ccaaaacaat aaatgctgta ctagctatca aatactcttt aagttctcta
       61 actacagcaa tattttttag atatggtcta actgttgaaa ataagacact attctgcgaa
      121 actaattttc tagcacggga aggcgcttgt tcaggtgaaa gatattgtag atttttgtag
      181 ttgattatgt tcttttttct atcaatacta gacgtatcta tatacctaaa ggatttctct
      241 ggcttatttt gcccaaaatt ccaataaatt gattttatcc tcacccactc ccaagtatca
      301 ggaatatcat aaggaacatc aatttcttga gtacttccat cagcaaactt cccataatgt
      361 ttcttatgtg cttcaagtat ataaaaaggc gtaaaaatac gcctatagat aatggggttg
      421 aaataggttt attgttgatg agattgtaga taattcaatt ttttacttcc aatcgaatat
      481 tcaaaacctc caccttttct gcctgtaatt gttcatcata aaattcaata tcttcaggat
      541 tttccccttg gcaacctcgg cagaaatatt cttccgctcg atcaggattc aaaaatcgac
      601 aagcacaaac aaaacagtcg ccatcatcat ttattgagat aatatagtag attgaaataa
      661 gatgtaaaca aatcgattag gaaagttaaa ttagtttcta gaaattttta gcagatgtag
      721 tgtactattc tagtctcaat ttactatggc ttcaaatata tctttcgaaa aaatatttac
      781 agatgtgtaa ttttgaagct tgcaaaagtt agtaaacttg tagatttcga tttgaagtaa
      841 cttgttttct tgcccgatat tgtttttgaa attgaatttt tccatagtga ctccttgatt
      901 ttcttctaca cgtctgatga taaatctaat tcgcaaaaga gtcaagagga tttttcgaaa
      961 aataaatagc gaccgaaatc gctattttaa gggttatagg tatttgatgg cttagactgc
     1021 tgtgtgactg tttacccaca ggcaatcttt cttggctcta taatatttgt agtgggtaaa
     1081 tccactatag atattatgga gcctatttta ttgtagaaaa aaagtcccat aaga
//
LOCUS       DAVLIK010000131         1054 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLIK010000131 DAVLIK010000000
VERSION     DAVLIK010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.131"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            128..574
                     /locus_tag="VXE87_002167"
                     /pseudo
     CDS             128..574
                     /locus_tag="VXE87_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            587..757
                     /locus_tag="VXE87_002168"
     CDS             587..757
                     /locus_tag="VXE87_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843612.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT          385 a          128 c          200 g          341 t
ORIGIN      
        1 aaaaatacca tcaggattat ataagattga tacaggaaaa gttttatttg atggtataaa
       61 tattaatcaa atagataaaa aaatattaag tcaaaattta ggagtagttc cacaggattc
      121 atttttattg aaccgaagta ttcttgataa tataacttta aagcacgaag ttacttcaca
      181 aaagatatag gaagtttgta aagcagttca aatctatgat gaaatcatgg ctatgccgat
      241 gaaatttaat actatcatct cagagatggg gtcaaatatt tcaggtgggc aaaggcaacg
      301 gatagcactg gcacgtgcat taataaataa tcctagtatt gtaattttag atgaagcaac
      361 tagtgcttta gacactatta atgaggaaag aataacaaag tatataaaaa gtcagggctg
      421 tactcacata attgtaactc atagattgtc aacgattaag gatgcggata ttatttttgt
      481 aatgaaaggt ggtaagattg ttgagtcagg aaatcataag tacttaatgg atcttggtgg
      541 agagtactac agcttatata caaaaaggaa atgaggtgta aagaaaatga agaaagaaaa
      601 tgaatatgta attttaacaa cagcctcact aggggtgatg attggaatag tgtttgcaat
      661 ttttttagat tttccagttg aatatggtat ttctttaggc ttgttgaatg gaatagtatt
      721 gggttcgctg attgtttaca aaaacaataa gaattaagca taattttttg ctgtaaacta
      781 aggagtagag atggctatag ttgaaattat aaatctaaca aaaagcttta aagatattga
      841 agttattcat aacacttaaa taatagagca actacagtag tagcttaaaa acatgattaa
      901 atcgctattc ttaggagtag cggtttttct ttttgtttaa tactctttga aaatctcttc
      961 aaaccacgtc agctttgcct tgccgtactc aagtacagcc tgcgactcgc ttcctagttt
     1021 gctttttgat tttcattgag tataaaaagg gtta
//
LOCUS       DAVLIK010000132         1054 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLIK010000132 DAVLIK010000000
VERSION     DAVLIK010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.132"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..867
                     /locus_tag="VXE87_002169"
                     /pseudo
     CDS             1..867
                     /locus_tag="VXE87_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            860..>1054
                     /locus_tag="VXE87_002170"
     CDS             860..>1054
                     /locus_tag="VXE87_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0843613.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNH"
BASE COUNT          397 a           95 c          206 g          356 t
ORIGIN      
        1 actcaactaa ttatttttta tatatgttaa aaaaacttga caagaatgga tttggaaagg
       61 ttaagacagt gataacatgc catggatggg ttgaatataa cttaaaaaag aaattcttga
      121 cttattttga tttttggaca tattctatgg gagatgcttt tatttgtgta tctgaaacta
      181 tgaaaaaaag attggagagt ataataaaaa aataagaaga tagttgcaat aaataacgga
      241 attaatgtat caaatagcga tttaaatgta gtaggtgttc aagactttaa aaaagaattt
      301 tgtattccaa ataacaaaaa aatcatttgt tatgttggaa ggttggatcc agaaaaaagg
      361 ccggatagat tccttgaatt tgcagaaaaa ttatttttag tcagagaaga tgtgattttt
      421 attatggctg gaaatggtag tatgtgggct gctttgaaag aaaaaatttg ccatttgaaa
      481 tgtagagata atttcaggtt acttggtgaa atctatccag ctactatagt ttaccaaata
      541 tcggatttat tgtatattcc ttctgataca gaaggaatac ctatgtgtgt tttagagtca
      601 atgtcacaag gaactccggt tttagctagt aatattggcg ggttaagtga aattattgaa
      661 catagggttg atggattttt atttgagaag gaagatgttg agggagtgtg tgcttgtgct
      721 aattttttac tcaatgattc tgagtatttg aaatatatag gtgagaatag taaatcaaaa
      781 ataagaaaac atttttctgt gcaaaaaatg tttgtagaaa ccatgagagt atatgatgaa
      841 ttattagaga agagtagtca tggataggaa tatagatcaa gaattagtaa gtattataat
      901 accaacacat aataggtatg aatctctgat tagagctgtg aaaagttgtt tacatcaaag
      961 ttataaaaat atcgaagtta taattattga tgataattat agtaatgtaa atttaagaaa
     1021 taaaattatc catcaatttg gctataccaa tcat
//
LOCUS       DAVLIK010000133         1053 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLIK010000133 DAVLIK010000000
VERSION     DAVLIK010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.133"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..559
                     /locus_tag="VXE87_002171"
     CDS             <1..559
                     /locus_tag="VXE87_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0843614.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(507..1052)
                     /locus_tag="VXE87_002172"
     CDS             complement(507..1052)
                     /locus_tag="VXE87_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0843615.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          379 a          167 c          153 g          354 t
ORIGIN      
        1 gaataaagac gaaacaacct cttatcctat atatgaaatc ccagaagcat ggagatatat
       61 taaatttgct agcctagtta acttcagaat aggaaaaact cctccacgca gtgaagctac
      121 tttttgggga actgaaatac cttgggtatc tatatcagat atgcctatat ctggttatgt
      181 aactaatacg agagaatcta tttctaaatt agcattaaaa tcaaagaaaa tagacatttc
      241 acctaaagga actttattaa tgagttttaa attatctatt ggaaaagttg ccatattgga
      301 tattcctgcc actcataatg aagccattat atcgatattc ccctatgcta ataaagaaaa
      361 tattatcaga gattacttaa tgatattttt gccacttatc tctactttag gtgattcaaa
      421 agatgctatc aaagggaaaa cattaaatag taccagtatc tccgaattat taatccctat
      481 ttctaatcat gaagagatga aaagaatcat ttccaaagtt gatttacttt ttcaaaaagt
      541 ttctcaactt tttgagtaat aagttcctgt tcctcaaaag gagctaacgg aattaatagc
      601 tcgcttagtg tagttttagg aatattatat aaagcttgac ctgatagttt agttattgct
      661 ttcaattgtt tataaaataa cggagaggac aagttaaata atagaaattt tgaaataatc
      721 tctgaacttt cgaatggtgt taattggaaa ataaatccac cagccacaac accatcatag
      781 tctttatcga ttcttgcaaa ctttccaata tgttctaaag aggttgatac aggtgttatt
      841 agctgattat gttttaaata aacttgctca gaggagatga attgtgtatc aatgtagtaa
      901 tcgttatcca acagagaaaa ttctaaaggc ttaatattac caccacgtat aattctaaca
      961 cctttattat taatgcttaa atcgcccttc ttgtaagaaa gacctgtatt cattgaaaaa
     1021 atatctttta tttttataac aacccaattc ata
//
LOCUS       DAVLIK010000134         1025 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLIK010000134 DAVLIK010000000
VERSION     DAVLIK010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1025
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.134"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            112..294
                     /locus_tag="VXE87_002173"
     CDS             112..294
                     /locus_tag="VXE87_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0843616.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLCFNEKFGTENT"
     gene            304..669
                     /locus_tag="VXE87_002174"
     CDS             304..669
                     /locus_tag="VXE87_002174"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0843617.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            666..>1025
                     /locus_tag="VXE87_002175"
     CDS             666..>1025
                     /locus_tag="VXE87_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0843618.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKG"
BASE COUNT          423 a          124 c          174 g          304 t
ORIGIN      
        1 ttatttataa caagaggata gaaatgaccg aattagaaag aaaaaatcga aaaattagct
       61 aagaaatatt ctgataactt aaacatcaaa gttcaagaga gagttcgtga aatggcaaat
      121 gataataaga gccattattt gatatacaga gttttaggta tttcatttga agaaggagaa
      181 aatatcgatt tgtatcaaaa taaaggtcgt tttttataca aatatgctgg ttcattttta
      241 gaagaagctg cagtactatg ctttaacgaa aaatttggta cagaaaatac ttaaaaagtt
      301 aacattccta attctgaaag tacaaaacct aagacttttg aaattgattg tttagtcgga
      361 gaaaaacacg catacgaaat aaaatggtgg gatgcaacta cagatggaga ccatataact
      421 aaagaacaca ctagaataaa agttattcat aacaaaggat atataccaat tcggttaatg
      481 ttctactatc caaatagaac tcaagctata aaaattcagc aaactttaga aacattgtat
      541 aacggtattg gagggaaata ttattatgga gattctgcct gggaacattt aagagcagtg
      601 accggtattg atttacttag tattctaaca gatattgcaa ataaaaaaac aggggtaaaa
      661 tcaaaatgac agtattaaaa ggagataact tagaaatatt aaaaactatt gaatcctcaa
      721 gtattgattt aatctatatg gaccctcctt tctttacaca gaaaacccaa aaattatcta
      781 ataacaaaaa tattatgtat tcattcgaag atacgtggac ttcgattgag gattacaaag
      841 aatttttgtc tgtaagatta gaagaatgca aaagagtgct aaaaaatagt ggcagtattt
      901 tcgttcattg tgataaaatt gcaaatcatc atattagatt aattttagat aatatctttg
      961 gagcagatat gtttcaaagc gaaattatat ggaactataa acggtggtct aattcaaaaa
     1021 aggga
//
LOCUS       DAVLIK010000135          983 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVLIK010000135 DAVLIK010000000
VERSION     DAVLIK010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.135"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(110..983)
                     /locus_tag="VXE87_002176"
                     /pseudo
     CDS             complement(110..983)
                     /locus_tag="VXE87_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          274 a          195 c          154 g          360 t
ORIGIN      
        1 aaaaataagc tccataatat ctatagggga tttacccact acaaatatta tagagccaaa
       61 aaataaaacg ccagttctgt actgcacccc aaacagttag acaattaatt tatccgaagg
      121 atttagttct gtattgcaca gggctaagtc cttttagttt taccttaatt ctcttgttgt
      181 tgtaataatc aatatagtct ataatagctt gttccaattg attaagtgat ttaaatgttt
      241 tctcatagcc ataaaacatt tccgatttca gaatcccaaa gaaggactcc accatagtgc
      301 ttctctgtga atgcctgttc caacattgtt tgtacttgtt ctaaattaga cgaacaagaa
      361 agattaaaag caataatttc gctgttaaag ccatctaaaa ctggtgataa gtaaagcttt
      421 tgagtacttg ctggaatggc aaattcagtc acatctgtgt agcacttttc cattgtttta
      481 gagccttcaa attggccttg aatgagattc tctgccttct taccaacgtc tcctttatga
      541 gaagaatatt ttcgtttctg tcgcatttta gcttgtaaat tgagtacttt catcaagcct
      601 tgaactcttt tatgatttac cagataacca cgatttctta gttctaaatg aacccgacga
      661 taaccataat ttcccttgtg ttcgataaaa atggattgaa tttcagcttt aagctcttgg
      721 tccttatctg ttttgtctag ctgtttcaag tgatagtagt aggtccaacg agctagttta
      781 atggctttta gaagaagatc taacgaaaac tcagtcatta attcttgaac aatttctgtc
      841 tttcttcttt ctctttttcc tccttcaatc ggagttctct taactttttt aggatggcat
      901 tctccgctct caggtactca ttttctgctt gaagacgttc taattctgtc ctctcttcag
      961 gtctcttttt tggcttacgt ccc
//
LOCUS       DAVLIK010000136          970 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVLIK010000136 DAVLIK010000000
VERSION     DAVLIK010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..970
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.136"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..>970
                     /locus_tag="VXE87_002177"
     CDS             <1..>970
                     /locus_tag="VXE87_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV0843619.1"
                     /translation="YDAPSCPDCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFK
                     CYHCSKMMVAETPLVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLN
                     DFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRY
                     DRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQF
                     ERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHY
                     QIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEK"
BASE COUNT          305 a          208 c          158 g          299 t
ORIGIN      
        1 actacgacgc cccatcttgc cctgattgtg gaagtctaat gaagaaatat gactttcaaa
       61 aaccgtctaa gatcccttac ctcgaaacaa ctggtatgcc ttctagaatt ctccttagaa
      121 aacgccgttt caagtgctat cactgttcaa aaatgatggt tgctgagact cccctggtaa
      181 agaaaaatca ccaaatccct cgtatcatca accaaaaaat tgctcaaaag ttaattgaaa
      241 aaatttctat gactgatatt gcccatcagc tggccatttc aacttcaact gtcattcgca
      301 agctcaatga ctttcacttt gagcatgatt tttctcggct tccaaagatt atgtcttggg
      361 atgagtatgc cttcactaag ggaaagatga gtttcattgc gcaagatttt gataatctta
      421 atattatcac tgttcttgaa ggcagaacac aagctgtcat ccgaaatcac tttcttcgct
      481 acgatagagc cgttcgttgt caagtgaaaa tcattacgat ggatatgttt agtccttact
      541 atgacttggc taaacagctt tttccgtgtg ctaaaatcgt tctagatcgt ttccatatta
      601 tccaacatct cagccgtgcc atgagtcgtt ttcgtgttca aattatgaat cagtttgaac
      661 gaaaatctca tgaatacaag gctatcaagc gttactggaa actcatccaa caggatagtc
      721 gtaaattgag cgataaacgt ttttatcgcc ctacttttcg catgcactta acaaataaag
      781 aaattcttga caagatttta agctattcag aagacttgaa acaccactat cagatctatc
      841 aactcttact ttttcacttt cagaacaaag accctgagaa atttttcgga ctcattgagg
      901 acaatctgaa gcaggttcat cctatttttc agactgtctt taaaaccttt ctaaagaaca
      961 aagagaaaat
//
LOCUS       DAVLIK010000137          963 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVLIK010000137 DAVLIK010000000
VERSION     DAVLIK010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.137"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..480
                     /locus_tag="VXE87_002178"
     CDS             <1..480
                     /locus_tag="VXE87_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0843620.1"
                     /translation="ISKSLCAPGLRIGYICANEKIVKKLEKKVIPFNVSNINQCIAEK
                     ILENFPLSLSICSDIESSFRQLDLFMEKYTTQKSEKACGFRLYQLKAKYDGNKIIDIL
                     TERGFLIRNISASYPELGENWIRISNGTLSEIKDLMHIMKDIFEDFDDKASDSYDKG"
     gene            523..>963
                     /locus_tag="VXE87_002179"
     CDS             523..>963
                     /locus_tag="VXE87_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843621.1"
                     /translation="MKLSSDLNILIRQLSYFIKDKEMLQQKIFGNFLDRFEEAYEQHF
                     FDIFDSLTGGIKISDVDWILGEEKLIKFLGRKNKNGQYLYVLPTNDGYLLRGSETYYH
                     YLSNVPYDYFKLIDKNIFIDGLKSTQNFLTEFIQYINSENSLTLK"
BASE COUNT          366 a          109 c          170 g          318 t
ORIGIN      
        1 atatcgaagt cactatgtgc tcctggatta agaataggct atatatgtgc taacgaaaaa
       61 attgtaaaaa aattagaaaa aaaagtaatt cctttcaatg tttctaatat caatcaatgt
      121 atagctgaaa aaatattaga aaattttccg ctctctctaa gtatatgttc agacattgag
      181 tcttcattta gacaattaga tttatttatg gagaaataca ctactcaaaa gtctgaaaag
      241 gcgtgtggtt tcaggttata ccagttgaaa gcaaaatatg atggtaataa aataatagat
      301 atactaacgg aaagaggttt tttgataaga aatataagtg cttcatatcc tgaattgggt
      361 gaaaattgga taaggattag taatggcacg ttatcagaga ttaaagattt gatgcacata
      421 atgaaagata tctttgaaga ttttgatgac aaagccagtg atagttatga caaggggtag
      481 gtgttgaaaa taaaagatag tgcggagatt ttgaataata atatgaaatt aagtagtgac
      541 ttaaatattt taataaggca actctcttat tttataaaag acaaggaaat gttgcaacaa
      601 aagatttttg gtaatttctt agatagattt gaagaggctt atgagcagca cttttttgat
      661 atttttgatt cacttactgg gggaattaag attagtgatg ttgattggat tttaggtgaa
      721 gaaaagttga ttaaatttct tgggagaaaa aataaaaatg gtcaatacct ctacgtactt
      781 ccaacaaatg acggctattt actcagaggt tctgaaacat actaccatta tttatcgaat
      841 gtaccatatg attattttaa actcattgac aaaaatatat ttatcgatgg cttgaaatct
      901 acacaaaatt ttttaacgga attcatccaa tatataaatt cagaaaactc tttgactctt
      961 aaa
//
LOCUS       DAVLIK010000138          963 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVLIK010000138 DAVLIK010000000
VERSION     DAVLIK010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.138"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            81..560
                     /locus_tag="VXE87_002180"
     CDS             81..560
                     /locus_tag="VXE87_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0843622.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            654..725
                     /locus_tag="VXE87_002181"
     tRNA            654..725
                     /locus_tag="VXE87_002181"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:687..689,aa:Glu,seq:ttc)
BASE COUNT          371 a          133 c          222 g          237 t
ORIGIN      
        1 gagctaaagg gaacagaatg gagaaaatgg aacaaatgtg ttttctaatc tgttagactg
       61 tatctagaaa ggggaaaatt atgattaaag aattgtatga agaagtccaa gggactgtgt
      121 ataagtgtag aaatgaatat taccttcatt tatgggaatt gtcggattgg gagcaagaag
      181 gcatgctctg cttacatgaa ttgattagta gagaagaagg actggtagac gatattccac
      241 gtttaaggaa atatttcaag accaagtttc gaaatcgaat tttagactat atccgtaaac
      301 aggaaagtca gaagcgtaga tacgataaag aaccctatga agaagtgggt gagatcagtc
      361 atcgtataag tgaggggggt ctctggctag atgattatta tctctttcat gaaacactaa
      421 gagattatag aaacaaacaa agtaaagaga aacaagaaga actagaacgc gtcttaagca
      481 atgaacgatt tcgagggcgt caaagagtat taagagactt acgcattgtg tttaaggagt
      541 ttactatccg tacccactag taagtcatgc aaaaaaaatg aaaaaaatta gaaaaagtag
      601 ttgacaaagt ttgaaaagac tgtataatag taagagttga aaataacaac tcaggtccgt
      661 tggtcaaggg gttaagacac cgccttttca cggcggtaac acgggttcga atcccgtacg
      721 gactatggta tgttgcgtca ggaccacttg atgaaaaaaa gtttaaaaaa acttaaaaat
      781 cttcaaaaaa gtgttgacaa gcgaaagcag ttgtgatata ctaatatagt tgtcgcttga
      841 gagaagcaag tgacaaagac ctttgaaaac tgaacaagac gaaccaatgt gcagggcgct
      901 acaacataag ttgtagtact gaacaatgaa aaaacaataa atctgtcagt gacagaaatg
      961 agt
//
LOCUS       DAVLIK010000139          872 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVLIK010000139 DAVLIK010000000
VERSION     DAVLIK010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..872
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.139"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..234
                     /locus_tag="VXE87_002182"
     CDS             <1..234
                     /locus_tag="VXE87_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0843623.1"
                     /translation="KINRLRMVAFDFIENKKHEEIGLIAQEAETIVPKIVSRDPENPD
                     GYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            231..347
                     /locus_tag="VXE87_002183"
     CDS             231..347
                     /locus_tag="VXE87_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HEV0843624.1"
                     /translation="MNNNMLTNIALKAIQELALENRKRTHRLENLENEHRTA"
     gene            328..531
                     /locus_tag="VXE87_002184"
     CDS             328..531
                     /locus_tag="VXE87_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843625.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMITSNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            534..>872
                     /locus_tag="VXE87_002185"
     CDS             534..>872
                     /locus_tag="VXE87_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843626.1"
                     /translation="MAETNQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVK"
BASE COUNT          330 a          159 c          174 g          209 t
ORIGIN      
        1 aaaatcaaca gattaagaat ggttgcattt gatttcatcg aaaataaaaa acatgaggag
       61 attggtctaa tagctcaaga ggctgaaacc atcgttccaa aaattgtctc acgagatcct
      121 gagaatccag atggctatct gcatatcgac tataccgctt tagttcctta cttaatcaag
      181 gctattcaag aattaaatca aaaaatagaa aaaatggaga aaacaatagc atgaataaca
      241 acatgttgac caatatcgca cttaaagcaa ttcaggagct tgctcttgaa aatagaaaac
      301 gaacacacag attggagaac ttagaaaatg aacacagaac agcttaacca agccttacaa
      361 atgacaattc gtgaaatgtc aacaacttca acagattcga tgattacaag taatttcttg
      421 agtattcagt tgaatgagca aagggaagag aatcaaagac ttcaagcacg agtggatgag
      481 ctggaagctc tgcttgatga acaaactaaa ccagcagaca aaggagaata gacatggcag
      541 aaacaaatca aaacacagat aacttactag accttacaaa aatcacagaa ccatttgatc
      601 ttgcgagtgc tttgcgctac atgaaagaaa atggagagtt cattcgttgc aagaatgtaa
      661 gcgatgactt ctatatgtat cgtgatgttc aaaaacgtcc tgtgatcgta aatggccgtc
      721 gccaactcaa ggatgttgaa accgtttggg cgttcaacca gtggggtggt acaatcgcaa
      781 caatcaacgt agccgttctg ttgaatcatg aattctatat catgaaattt gatgcagagg
      841 gcaatcctga ctggacggat ccaacggtaa aa
//
LOCUS       DAVLIK010000140          872 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVLIK010000140 DAVLIK010000000
VERSION     DAVLIK010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..872
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.140"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..234
                     /locus_tag="VXE87_002186"
     CDS             <1..234
                     /locus_tag="VXE87_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0843627.1"
                     /translation="KINRLRMVAFDFIESKKHEEIGLIAQEAETIVPRIVSRDPENPD
                     GYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            328..531
                     /locus_tag="VXE87_002187"
     CDS             328..531
                     /locus_tag="VXE87_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843628.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            534..>872
                     /locus_tag="VXE87_002188"
     CDS             534..>872
                     /locus_tag="VXE87_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843629.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVK"
BASE COUNT          332 a          156 c          174 g          210 t
ORIGIN      
        1 aaaatcaaca gattaagaat ggttgcattt gatttcatcg aaagtaagaa acatgaggag
       61 attggtctaa tagctcaaga ggctgaaacc atcgttccaa gaattgtctc acgagatcct
      121 gagaatccag atggctatct acatatcgac tataccgctt tagttcctta cttaatcaag
      181 gctattcaag aattaaatca aaaaatagaa aaaatggaga aaacaatagc atgaataaca
      241 acatgttgac caatatcgca cttaaagcaa tttaagagct tgctcttgaa aatagaaaac
      301 gaacacacag attggagaac ttagaaaatg aacacagaac agcttaacca agccttacaa
      361 atgacaatta gtgaaatgtc aacaacttca acaaattcga tgattacaag taatatcttg
      421 agtattcagt tgaatgagca aagggaagag aatcaaagac ttcaagcacg agtggatgag
      481 ctggaagctc tgcttgatga acaaactaaa ccagcagaca aaggagaata gacatggcag
      541 aaacaattca aaacacagat aacttactag accttacaaa aatcacagaa ccatttgatc
      601 ttgcgagcgc tttgcgctac atgaaagaaa atggagagtt cattcgttgc aagaatgtaa
      661 gcgatgactt ctatatgtat cgtgatgttc aaaaacgtcc tgtgatcgta aatggccgtc
      721 gccaattaaa ggatgttgaa accgtttggg cgttcaacca gtggggtggt acaatcgcaa
      781 caatcaacgt agccgttctg ttgaatcatg aattctatat catgaaattt gatgcagagg
      841 gcaatcctga ctggacggat ccaacggtaa aa
//
LOCUS       DAVLIK010000141          848 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVLIK010000141 DAVLIK010000000
VERSION     DAVLIK010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.141"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(220..848)
                     /locus_tag="VXE87_002189"
                     /pseudo
     CDS             complement(220..848)
                     /locus_tag="VXE87_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795721.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
BASE COUNT          208 a          205 c          149 g          286 t
ORIGIN      
        1 atactcttct gtaaaagtat cggaatcgaa aatagttgtg taccttaagg cgtcattaat
       61 cttactcacg gcttttgaca aacttatatt ttcaactagg ctatctgcaa taattttacg
      121 tgataacgac tcaactgttt tcttcctaaa ttcaagacct gccaatttgt tttctcctgc
      181 gatacgttgc atatcacttg taatttttgg ctcaactcct gaaattttgg acaatagttg
      241 ttcgctataa aatttcgcct tggcttctct tgtatcttga ttatacacct tttccccgtc
      301 tttcgcaaca tacttgctat accactcttt ataagtcata tcggcaggca cgtactcaac
      361 tttacctgtc tctggattcc ttgctctgcg cttcaacttg ctgtagtctg cgtcctcatc
      421 gtatccgaca gtagtagacc tacaccaagg gtgcataggc ggacaattga caccagggac
      481 agccttatcc ctatcataga cctgattgtc atgctcctga caaatccgtg atgtacgctt
      541 gtctaagacg gccacaaaga tatacttttc tatgtctgct tcttcatagc tgagtagttc
      601 catttggtta tgaaaaaagg ctgattctgt ccgaaccaaa cgtcttgcat cgttctgacc
      661 tacattgaac ctctcagcaa ttgcttgtgc agtttctcgt gtatctcggc ctgtcatgag
      721 gctcataagt agttcatctt ttatgctaga agtaagcttc cccgtattct tccagatgtc
      781 tgtagagtag gtacttccgt cacctaccca actgaaagac tgtagatgtt taatctcgct
      841 ctcaggaa
//
LOCUS       DAVLIK010000142          754 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVLIK010000142 DAVLIK010000000
VERSION     DAVLIK010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.142"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..278
                     /locus_tag="VXE87_002190"
     CDS             <1..278
                     /locus_tag="VXE87_002190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEV0843630.1"
                     /translation="AEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFD
                     LKNGSLHELYEKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            280..489
                     /locus_tag="VXE87_002191"
     CDS             280..489
                     /locus_tag="VXE87_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0843631.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSIDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            486..>754
                     /locus_tag="VXE87_002192"
     CDS             486..>754
                     /locus_tag="VXE87_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0843632.1"
                     /translation="MIDIALAIAKKAHAGQVDKADVDYIQHPLYVASQVKTEQEKAVA
                     LLHDVIEDSDITAADLLASGLSNEVVTAVQILTKKKGQSYQEYLG"
BASE COUNT          268 a          100 c          164 g          222 t
ORIGIN      
        1 tcgcagaagg ttataaaatt gtaaaagtaa aaaacacttg gttagtagat ggaccataca
       61 aaggtgtgaa tacagtcgtt gaaaaagatg gtatcaactt tgaaatgcag tatcatactc
      121 aggaaagttt cgacttaaaa aatggttcat tacatgaact ctatgagaag tatcgtgata
      181 cgaatacatc tgatctagaa cgcatgaaat tatttaagga aatgcttgat ttaagcaatg
      241 ggcttgagat tcctaaaaat atagagaggg tgaagtgatg tgaaagatat taaatactac
      301 cgcacaacga cgaacaatgc tcaagtactt cgtttgattg atggtgtcat gcaagttttt
      361 gacattgaaa aaaagtgggt taatagcata gattggttta ataaaatctt ttttaatgac
      421 tttacggatt ttgaagaaat ttcagaaaat gatgcattta cttatattga caggatggta
      481 gcggcatgat tgatattgct ttggctatcg ctaaaaaagc acatgcaggg caggtagata
      541 aagcggatgt tgattacata cagcatcctc tctatgtggc cagtcaagtc aaaactgaac
      601 aagaaaaagc tgtcgctctt ttacatgatg tgattgagga tagcgatata actgctgccg
      661 atttattggc gtctggtttg tcaaatgaag ttgttacagc ggtacaaatt ttgacaaaga
      721 aaaaaggtca aagttatcaa gaatatcttg ggaa
//
LOCUS       DAVLIK010000143          692 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVLIK010000143 DAVLIK010000000
VERSION     DAVLIK010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.143"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            220..438
                     /locus_tag="VXE87_002193"
     CDS             220..438
                     /locus_tag="VXE87_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0843633.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
BASE COUNT          302 a           79 c          121 g          190 t
ORIGIN      
        1 cgatagaaat taaaaactct atcgtctttt ttatactcaa aattaggagg taaaaatggt
       61 aaggataaga ggtcccactt aaaacaattt atggcaaaat aaggacggaa taacacaaca
      121 aattctctaa aacaaatcac taaatcaatg taagattgaa tgaaatcaat atttatgcta
      181 taattaaata aatctaatga agaaaaaaag agggatatta tggcacttaa ctataaacca
      241 ttatggatac agttagcaaa aaaaggacta aagaaaacag atgtaatagc tatggcagga
      301 cttacaacaa atgttatggc acaaatggga aaggataaac caattacatt taagaattta
      361 gaaagaatat gtaaggcttt atcttgcact cctaatgata ttattagttt tgaagataat
      421 tttagtgacg aggaatagaa aatgacttta aggacagaag atcaagttag ggattatgca
      481 agagaagtat aggctttaat gaagttgaag aaaacatcaa tcaaggtact ggtcaaataa
      541 ctacttttaa tcaattaggc ttcaagggat attcagataa gccagatggt tggtatttac
      601 ctaaaaatat gaatgatgta gcaataatcc ttgaaacaaa atcagaagaa agagatatta
      661 gcaaacaaat ttttattgat gagttaatga aa
//
LOCUS       DAVLIK010000144          668 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVLIK010000144 DAVLIK010000000
VERSION     DAVLIK010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..668
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.144"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            83..445
                     /locus_tag="VXE87_002194"
     CDS             83..445
                     /locus_tag="VXE87_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0843634.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          223 a           83 c          121 g          241 t
ORIGIN      
        1 atctacaacc tcaaaacagt gttttgagca acctgaggct agtttcctag tttgctcttt
       61 ggttttcatt gagtataaca gattgttaga agttggttta aatttcctaa tcagtttgtt
      121 cacatttacc ttcgatatat tatatcccat agttaaggtt ggtcatacag atgattatag
      181 tcatggagcc gtaaaactta gtgtttcttt agttgacaaa gatgccatga aaaaaatatc
      241 tgtaactgta ataggatatt ttgaaataaa tatagatgaa aatatcaccg atattctata
      301 cgtaaatggt actgctattc tttatcatta tttacgttct attgtttcaa tagtttcggc
      361 aattgatagc agtgaagcaa tgttgctacc taccattaat gttttagagt tactagataa
      421 atctcaacct tttgaagaag aataatttat tagctcacta aattgagggt aaggaaaagt
      481 aaaatcagta agaaaaatgt cttgcattat acagcaacct tttgggaatg agtagatgga
      541 ttgaataaaa ttttattaag agtggatgat ttatctgtag attattattg gacagttagt
      601 cttgaagtag tctaagaatt aggttataat cagtagaatc cttgctaata atgaggaggt
      661 tagtttat
//
LOCUS       DAVLIK010000145          608 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVLIK010000145 DAVLIK010000000
VERSION     DAVLIK010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.145"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..447
                     /locus_tag="VXE87_002195"
                     /pseudo
     CDS             1..447
                     /locus_tag="VXE87_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          214 a          103 c          114 g          177 t
ORIGIN      
        1 aactatctta ctgacaatcc agacgcttat ttgactgaaa tagcttctga atttggctgt
       61 catccaacta ccatccacta tgcgctcaaa gcgatgggct acactcgaaa aaaagaacca
      121 cacctactat gaacaagacc cagaaaagta gccttatttc ttaagaattt taatagttta
      181 aagcacctag cacctgttta gattgatgaa acaggattcg atacttattt ttatcgagaa
      241 tatggtcgct cattaaaagg tcagttaaga agaggcaaag tatctggaag aagatatcag
      301 agaatttctt tggttgcagg tctaacaaat ggtgagttaa tcgctccaat aacttacgaa
      361 gagacgatga cgagcgactt ttttgaagct tggtttcaga aatttctctt accaacatta
      421 aacacaccat cggttattat agtaaaataa aataagaata ggataaatcg atcaggacag
      481 taaaatcgaa ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatctac
      541 tatattatgg ataatgcaag attccataga atggggaagc tagaactttt atgcggagag
      601 tttgggca
//
LOCUS       DAVLIK010000146          608 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVLIK010000146 DAVLIK010000000
VERSION     DAVLIK010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.146"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..>608
                     /locus_tag="VXE87_002196"
     CDS             <1..>608
                     /locus_tag="VXE87_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV0843635.1"
                     /translation="SRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHF
                     TTYGKQEGVAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLE
                     RFNQLLFRMDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTIL
                     PHSAYSETLYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTN"
BASE COUNT          164 a          149 c          111 g          184 t
ORIGIN      
        1 tcccgttttc tttccagaac tgacgaggaa acagtccata gtttgcgatg cctcaacctt
       61 gaattggtcg aattcttttt acagtttcac cagctaaacc aactcattgt agatatcgat
      121 tctacccatt tcacaactta tggcaagcaa gaaggtgttg cttataacgc ccactatcgt
      181 gctcatggct atcatcctct ttatgctttc gaggggaaga caggttattg tttcaatgcc
      241 cagcttcgtc ctggtaatcg ttattgttct gaagaggcag acagctttat cacacctgtt
      301 ttagaacggt ttaatcaact tctctttcga atggatagtg gctttgcgac cccaaaatta
      361 tacgatttaa ttgaaaaaac agggcaatac tacctcataa aactcaagaa aaatactgtt
      421 ctgagccgtc ttggagacct ttccctccct tgcccacagg atgaggactt aaccatcttg
      481 ccccactccg cctactcaga aactctctat caagcaggat cttggtcgca caagcgtcgt
      541 gtctgccagt tctctgaacg aaaagaagga aacttgttct acgatgttat ttctctcgtt
      601 acaaatat
//
LOCUS       DAVLIK010000147          484 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVLIK010000147 DAVLIK010000000
VERSION     DAVLIK010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.147"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            1..393
                     /locus_tag="VXE87_002197"
     CDS             1..393
                     /locus_tag="VXE87_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0843636.1"
                     /translation="MAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADTVKKYEFG
                     IGDAGELEYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVTFEGQVSVKLG
                     GGGVNAVIEFTLKIALQSELTFVDGIGG"
BASE COUNT          156 a           85 c          117 g          126 t
ORIGIN      
        1 ttggccttta gtgaaacgaa aggcaattat cagaatcttg tagggcttaa ggaagtacct
       61 gaatttggta tcgagcccga aaaagtagaa aatactactc ttgcagatac ggtgaagaag
      121 tacgagtttg gtatcgggga cgcaggagaa cttgagtaca agttcgctta taataattca
      181 agcgcaacag ctccttaccg tgtattacgt aaggcagcag atggcaagaa aaaactctac
      241 tttgaacaaa cctacccaga cggtactaag gtcacttttg aaggtcaagt atccgttaaa
      301 ctgggcggtg gcggcgttaa tgccgttatc gagttcacac ttaagattgc attgcagtct
      361 gaattgacat tcgttgatgg aattggaggt taattaaatg gcgttaaaat acacaacttg
      421 gaaagttact gacgaaaaag agttgaagct acgtttgaca tctcatcaag ctgcaactgt
      481 ggaa
//
LOCUS       DAVLIK010000148          471 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.148, whole genome shotgun sequence.
ACCESSION   DAVLIK010000148 DAVLIK010000000
VERSION     DAVLIK010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.148"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..244
                     /locus_tag="VXE87_002198"
     CDS             <1..244
                     /locus_tag="VXE87_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV0843637.1"
                     /translation="IDKAETCVNDLMAEFNSVITTVTGIENRLGAVILAEIRNIHAFD
                     NPAQLQAFAGLDSSIYQSGQIDLAGRMVKRGSPHLR"
BASE COUNT          143 a           98 c           94 g          136 t
ORIGIN      
        1 cattgacaag gcggaaacat gtgtcaatga cttgatggct gagttcaact cggtcatcac
       61 gacggttact gggattgaga atcgtttagg ggcggtcatt ttagccgaga ttcgaaatat
      121 tcatgccttt gataatcctg ctcaattaca agctttcgct ggactggatt cttctattta
      181 tcagtcaggt cagattgatt tagctggaag aatggtcaaa cggggttccc ctcatctgcg
      241 gtaggtactc atacaagctg ccaaagcatg ccctcgcttt tcacctgctt ttaagaccta
      301 tcttaagact aagttagaac aaggaaaaca ttacaatgta gccatcatcc accttgcaaa
      361 aaaacttatc cgaaccctgt tttatatcct aaaaaagagc tgccatttga cgaacaaaaa
      421 gtgatgtaat ttctgaaatt aacacaggat tacctttgaa aaaatggact t
//
LOCUS       DAVLIK010000149          428 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.149, whole genome shotgun sequence.
ACCESSION   DAVLIK010000149 DAVLIK010000000
VERSION     DAVLIK010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.149"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            complement(<1..>428)
                     /locus_tag="VXE87_002199"
     CDS             complement(<1..>428)
                     /locus_tag="VXE87_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0843638.1"
                     /translation="FDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANWGNNWNYAGP
                     KAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIELGSKDVLG
                     DGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENIT"
BASE COUNT          117 a          128 c           67 g          116 t
ORIGIN      
        1 tctgtgatgt tctcttttaa gcgtctgtct gatttttgtt ccatccaata cttcacgcta
       61 ccgctaccga cctgattcca ccaaacaacc gcattccttc cgcctttggg attccaacca
      121 tcaccaagca catctttact tccaagttcg ataccatttg aaaacacagg agaacgagaa
      181 aaagtagtat tcccatagaa gtttgctctc gatgaattcg aaaaatccac ttgatcataa
      241 aaaccgactt cattcctaca gtacattttc ccatcagtat tgacgttcca tgctttaggt
      301 ccggcatagt tccaattatt tccccagttc gcccagaagg ctgtccggac tccatgcccg
      361 gcaccattcc ccataccaac agagaactga ttgacacctg aaatccagcg accgccaccc
      421 tggtcaaa
//
LOCUS       DAVLIK010000150          427 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.150, whole genome shotgun sequence.
ACCESSION   DAVLIK010000150 DAVLIK010000000
VERSION     DAVLIK010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.150"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..354
                     /locus_tag="VXE87_002200"
     CDS             <1..354
                     /locus_tag="VXE87_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEV0843639.1"
                     /translation="KDKGYHRSQIIADSAESRLIEELRSEHGISRIKESRKGKDSIMA
                     GVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKEGNWLNKPEDKNNHLMDALRYSLQCI
                     EGGKATVRRRSDYGL"
BASE COUNT          148 a           73 c          103 g          103 t
ORIGIN      
        1 aaggacaaag gttatcatcg ctcacaaatc attgctgata gcgcagagtc acggctgatt
       61 gaagagctca ggtcagaaca tggcatatct agaataaaag agagtcggaa aggtaaggat
      121 agtattatgg caggcgtatc caaattgcaa ggatacgcta tttatgtgca tccagattgt
      181 aaaaacatca tggatgaatt ttatagttac tgctaccagc gagataaaga aggcaactgg
      241 ttgaataaac cagaggataa aaacaaccac ttgatggacg ctttgcgtta cagccttcaa
      301 tgtatcgaag gtggaaaagc aaccgtccgc agacgttctg attatggtct atagagagga
      361 aagacatgta ccaatattta acctatccac gggatggata tgatgagggt tctttgaaga
      421 aagacct
//
LOCUS       DAVLIK010000151          414 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.151, whole genome shotgun sequence.
ACCESSION   DAVLIK010000151 DAVLIK010000000
VERSION     DAVLIK010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.151"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..>414
                     /locus_tag="VXE87_002201"
     CDS             <1..>414
                     /locus_tag="VXE87_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0843640.1"
                     /translation="YLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQIPRII
                     NQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYAFTKG
                     KMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRA"
BASE COUNT          127 a           82 c           68 g          137 t
ORIGIN      
        1 ttatcttgaa acgactggta tgcctactag aattctcctt agaaagcgtc gattcaagtg
       61 ttatcactgt tcaaaaatga tggtcgctga aacttctatc gtcaagaaga atcaccaaat
      121 ccctcgtatt atcaaccaaa aaattgcgca aaagttaatt gaaaagattt ctatgaccga
      181 tattgcccat cagctttcca tctcaacttc aactgttatt cgtaagctca atgattttca
      241 ctttaaacat gatttttctt gtcttcctga gattatgtct tgggatgagt atgcttttac
      301 aaagggaaag atgagtttca ttgcgcaaga ttttgataat cttaatatta tcactgttct
      361 tgaaggcaga acacaagctg tcatccgaaa tcactttctt cgctacgata gagc
//
LOCUS       DAVLIK010000152          407 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060761
            SAMN33606616-rid17950053.denovo.152, whole genome shotgun sequence.
ACCESSION   DAVLIK010000152 DAVLIK010000000
VERSION     DAVLIK010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606616
            Sequence Read Archive: SRR23725931
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721808.1
            Genome Coverage       :: 272x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:32:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,160
            Genes (coding)                    :: 2,013
            CDSs (with protein)               :: 2,013
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 65 of 147
            Pseudo Genes (incomplete)         :: 61 of 147
            Pseudo Genes (internal stop)      :: 52 of 147
            Pseudo Genes (multiple problems)  :: 27 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606616-rid17950053.denovo.152"
                     /strain="AUSMDU00060761"
                     /serotype="14"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST156"
     gene            <1..>407
                     /locus_tag="VXE87_002202"
     CDS             <1..>407
                     /locus_tag="VXE87_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HEV0843641.1"
                     /translation="TKEKPTKPSGKLATTVEVDGTKADAQKELELSVATDKVTKTVKD
                     TVVYENLLAGETYKLTGQLMKITADKEEEVATKETTFVADASGNGTTSLEFEDVSLEA
                     GVKYVVYETAESEKEIDFKEGKEKHKVEHKDKD"
BASE COUNT          169 a           68 c           98 g           72 t
ORIGIN      
        1 acgaaagaaa aaccaacaaa accatcaggt aagcttgcga caactgtaga agttgacgga
       61 acaaaagctg atgcacagaa agagcttgag ttgtcagttg caacagataa agttacgaag
      121 acagtaaaag atactgttgt gtacgaaaat ctgttagctg gcgaaaccta caaactaaca
      181 ggtcagttga tgaagattac agctgacaaa gaagaggaag tagcaacgaa agaaacaact
      241 ttcgtcgcag atgcctcagg caacggtaca accagcctag agtttgaaga tgtgagcctt
      301 gaagcaggcg ttaagtatgt agtatatgaa actgcagaga gcgaaaaaga aattgacttc
      361 aaagaaggca aagaaaagca caaggtagaa cacaaagaca aagatga
//
